A Toolkit for Working with Justifications for Entailments in OWL Ontologies
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A Logical Framework for Modularity of Ontologies∗
A Logical Framework for Modularity of Ontologies∗ Bernardo Cuenca Grau, Ian Horrocks, Yevgeny Kazakov and Ulrike Sattler The University of Manchester School of Computer Science Manchester, M13 9PL, UK {bcg, horrocks, ykazakov, sattler }@cs.man.ac.uk Abstract ontology itself by possibly reusing the meaning of external symbols. Hence by merging an ontology with external on- Modularity is a key requirement for collaborative tologies we import the meaning of its external symbols to de- ontology engineering and for distributed ontology fine the meaning of its local symbols. reuse on the Web. Modern ontology languages, To make this idea work, we need to impose certain con- such as OWL, are logic-based, and thus a useful straints on the usage of the external signature: in particular, notion of modularity needs to take the semantics of merging ontologies should be “safe” in the sense that they ontologies and their implications into account. We do not produce unexpected results such as new inconsisten- propose a logic-based notion of modularity that al- cies or subsumptions between imported symbols. To achieve lows the modeler to specify the external signature this kind of safety, we use the notion of conservative exten- of their ontology, whose symbols are assumed to sions to define modularity of ontologies, and then prove that be defined in some other ontology. We define two a property of some ontologies, called locality, can be used restrictions on the usage of the external signature, to achieve modularity. More precisely, we define two no- a syntactic and a slightly less restrictive, seman- tions of locality for SHIQ TBoxes: (i) a tractable syntac- tic one, each of which is decidable and guarantees tic one which can be used to provide guidance in ontology a certain kind of “black-box” behavior, which en- editing tools, and (ii) a more general semantic one which can ables the controlled merging of ontologies. -
Understanding Semantic Aware Grid Middleware for E-Science
Computing and Informatics, Vol. 27, 2008, 93–118 UNDERSTANDING SEMANTIC AWARE GRID MIDDLEWARE FOR E-SCIENCE Pinar Alper, Carole Goble School of Computer Science, University of Manchester, Manchester, UK e-mail: penpecip, carole @cs.man.ac.uk { } Oscar Corcho School of Computer Science, University of Manchester, Manchester, UK & Facultad de Inform´atica, Universidad Polit´ecnica de Madrid Boadilla del Monte, ES e-mail: [email protected] Revised manuscript received 11 January 2007 Abstract. In this paper we analyze several semantic-aware Grid middleware ser- vices used in e-Science applications. We describe them according to a common analysis framework, so as to find their commonalities and their distinguishing fea- tures. As a result of this analysis we categorize these services into three groups: information services, data access services and decision support services. We make comparisons and provide additional conclusions that are useful to understand bet- ter how these services have been developed and deployed, and how similar ser- vices would be developed in the future, mainly in the context of e-Science applica- tions. Keywords: Semantic grid, middleware, e-science 1 INTRODUCTION The Science 2020 report [40] stresses the importance of understanding and manag- ing the semantics of data used in scientific applications as one of the key enablers of 94 P. Alper, C. Goble, O. Corcho future e-Science. This involves aspects like understanding metadata, ensuring data quality and accuracy, dealing with data provenance (where and how it was pro- duced), etc. The report also stresses the fact that metadata is not simply for human consumption, but primarily used by tools that perform data integration and exploit web services and workflows that transform the data, compute new derived data, etc. -
Deciding Semantic Matching of Stateless Services∗
Deciding Semantic Matching of Stateless Services∗ Duncan Hull†, Evgeny Zolin†, Andrey Bovykin‡, Ian Horrocks†, Ulrike Sattler†, and Robert Stevens† School of Computer Science, Department of Computer Science, † ‡ University of Manchester, UK University of Liverpool, UK Abstract specifying automated reasoning algorithms for such stateful service descriptions is basically impossible in the presence We present a novel approach to describe and reason about stateless information processing services. It can of any expressive ontology (Baader et al. 2005). Stateless- be seen as an extension of standard descriptions which ness implies that we do not need to formulate pre- and post- makes explicit the relationship between inputs and out- conditions since our services do not change the world. puts and takes into account OWL ontologies to fix the The question we are interested in here is how to help the meaning of the terms used in a service description. This biologist to find a service he or she is looking for, i.e., a allows us to define a notion of matching between ser- service that works with inputs and outputs the biologist can vices which yields high precision and recall for service provide/accept, and that provides the required functionality. location. We explain why matching is decidable, and The growing number of publicly available biomedical web provide biomedical example services to illustrate the utility of our approach. services, 3000 as of February 2006, required better match- ing techniques to locate services. Thus, we are concerned with the question of how to describe a service request Q Introduction and service advertisements Si such that the notion of a ser- Understanding the data generated from genome sequenc- vice S matching the request Q can be defined in a “useful” ing projects like the Human Genome Project is recognised way. -
Description Logics Emerge from Ivory Towers Deborah L
Description Logics Emerge from Ivory Towers Deborah L. McGuinness Stanford University, Stanford, CA, 94305 [email protected] Abstract: Description logic (DL) has existed as a field for a few decades yet somewhat recently have appeared to transform from an area of academic interest to an area of broad interest. This paper provides a brief historical perspective of description logic developments that have impacted their usability beyond just in universities and research labs and provides one perspective on the topic. Description logics (previously called terminological logics and KL-ONE-like systems) started with a motivation of providing a formal foundation for semantic networks. The first implemented DL system – KL-ONE – grew out of Brachman’s thesis [Brachman, 1977]. This work was influenced by the work on frame systems but was focused on providing a foundation for building term meanings in a semantically meaningful and unambiguous manner. It rejected the notion of maintaining an ever growing (seemingly adhoc) vocabulary of link and node names seen in semantic networks and instead embraced the notion of a fixed set of domain-independent “epistemological primitives” that could be used to construct complex, structured object descriptions. It included constructs such as “defines-an-attribute-of” as a built-in construct and expected terms like “has-employee” to be higher-level terms built up from the epistemological primitives. Higher level terms such as “has-employee” and “has-part-time-employee” could be related automatically based on term definitions instead of requiring a user to place links between them. In its original incarnation, this led to maintaining the motivation of semantic networks of providing broad expressive capabilities (since people wanted to be able to represent natural language applications) coupled with the motivation of providing a foundation of building blocks that could be used in a principled and well-defined manner. -
Open PHACTS: Semantic Interoperability for Drug Discovery
REVIEWS Drug Discovery Today Volume 17, Numbers 21/22 November 2012 Reviews KEYNOTE REVIEW Open PHACTS: semantic interoperability for drug discovery 1 2 3 Antony J. Williams Antony J. Williams , Lee Harland , Paul Groth , graduated with a PhD in 4 5,6 chemistry as an NMR Stephen Pettifer , Christine Chichester , spectroscopist. Antony 7 6,7 8 Williams is currently VP, Egon L. Willighagen , Chris T. Evelo , Niklas Blomberg , Strategic development for 9 4 6 ChemSpider at the Royal Gerhard Ecker , Carole Goble and Barend Mons Society of Chemistry. He has written chapters for many 1 Royal Society of Chemistry, ChemSpider, US Office, 904 Tamaras Circle, Wake Forest, NC 27587, USA books and authored >140 2 Connected Discovery Ltd., 27 Old Gloucester Street, London, WC1N 3AX, UK peer reviewed papers and 3 book chapters on NMR, predictive ADME methods, VU University Amsterdam, Room T-365, De Boelelaan 1081a, 1081 HV Amsterdam, The Netherlands 4 internet-based tools, crowdsourcing and database School of Computer Science, The University of Manchester, Oxford Road, Manchester M13 9PL, UK 5 curation. He is an active blogger and participant in the Swiss Institute of Bioinformatics, CMU, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland Internet chemistry network as @ChemConnector. 6 Netherlands Bioinformatics Center, P. O. Box 9101, 6500 HB Nijmegen, and Leiden University Medical Center, The Netherlands Lee Harland 7 is the Founder & Chief Department of Bioinformatics – BiGCaT, Maastricht University, The Netherlands 8 Technical Officer of Respiratory & Inflammation iMed, AstraZeneca R&D Mo¨lndal, S-431 83 Mo¨lndal, Sweden 9 ConnectedDiscovery, a University of Vienna, Department of Medicinal Chemistry, Althanstraße 14, 1090 Wien, Austria company established to promote and manage precompetitive collaboration Open PHACTS is a public–private partnership between academia, within the life science industry. -
Ontology-Based Methods for Analyzing Life Science Data
Habilitation a` Diriger des Recherches pr´esent´ee par Olivier Dameron Ontology-based methods for analyzing life science data Soutenue publiquement le 11 janvier 2016 devant le jury compos´ede Anita Burgun Professeur, Universit´eRen´eDescartes Paris Examinatrice Marie-Dominique Devignes Charg´eede recherches CNRS, LORIA Nancy Examinatrice Michel Dumontier Associate professor, Stanford University USA Rapporteur Christine Froidevaux Professeur, Universit´eParis Sud Rapporteure Fabien Gandon Directeur de recherches, Inria Sophia-Antipolis Rapporteur Anne Siegel Directrice de recherches CNRS, IRISA Rennes Examinatrice Alexandre Termier Professeur, Universit´ede Rennes 1 Examinateur 2 Contents 1 Introduction 9 1.1 Context ......................................... 10 1.2 Challenges . 11 1.3 Summary of the contributions . 14 1.4 Organization of the manuscript . 18 2 Reasoning based on hierarchies 21 2.1 Principle......................................... 21 2.1.1 RDF for describing data . 21 2.1.2 RDFS for describing types . 24 2.1.3 RDFS entailments . 26 2.1.4 Typical uses of RDFS entailments in life science . 26 2.1.5 Synthesis . 30 2.2 Case study: integrating diseases and pathways . 31 2.2.1 Context . 31 2.2.2 Objective . 32 2.2.3 Linking pathways and diseases using GO, KO and SNOMED-CT . 32 2.2.4 Querying associated diseases and pathways . 33 2.3 Methodology: Web services composition . 39 2.3.1 Context . 39 2.3.2 Objective . 40 2.3.3 Semantic compatibility of services parameters . 40 2.3.4 Algorithm for pairing services parameters . 40 2.4 Application: ontology-based query expansion with GO2PUB . 43 2.4.1 Context . 43 2.4.2 Objective . -
The Fourth Paradigm
ABOUT THE FOURTH PARADIGM This book presents the first broad look at the rapidly emerging field of data- THE FOUR intensive science, with the goal of influencing the worldwide scientific and com- puting research communities and inspiring the next generation of scientists. Increasingly, scientific breakthroughs will be powered by advanced computing capabilities that help researchers manipulate and explore massive datasets. The speed at which any given scientific discipline advances will depend on how well its researchers collaborate with one another, and with technologists, in areas of eScience such as databases, workflow management, visualization, and cloud- computing technologies. This collection of essays expands on the vision of pio- T neering computer scientist Jim Gray for a new, fourth paradigm of discovery based H PARADIGM on data-intensive science and offers insights into how it can be fully realized. “The impact of Jim Gray’s thinking is continuing to get people to think in a new way about how data and software are redefining what it means to do science.” —Bill GaTES “I often tell people working in eScience that they aren’t in this field because they are visionaries or super-intelligent—it’s because they care about science The and they are alive now. It is about technology changing the world, and science taking advantage of it, to do more and do better.” —RhyS FRANCIS, AUSTRALIAN eRESEARCH INFRASTRUCTURE COUNCIL F OURTH “One of the greatest challenges for 21st-century science is how we respond to this new era of data-intensive -
Description Logics
Description Logics Franz Baader1, Ian Horrocks2, and Ulrike Sattler2 1 Institut f¨urTheoretische Informatik, TU Dresden, Germany [email protected] 2 Department of Computer Science, University of Manchester, UK {horrocks,sattler}@cs.man.ac.uk Summary. In this chapter, we explain what description logics are and why they make good ontology languages. In particular, we introduce the description logic SHIQ, which has formed the basis of several well-known ontology languages, in- cluding OWL. We argue that, without the last decade of basic research in description logics, this family of knowledge representation languages could not have played such an important rˆolein this context. Description logic reasoning can be used both during the design phase, in order to improve the quality of ontologies, and in the deployment phase, in order to exploit the rich structure of ontologies and ontology based information. We discuss the extensions to SHIQ that are required for languages such as OWL and, finally, we sketch how novel reasoning services can support building DL knowledge bases. 1 Introduction The aim of this section is to give a brief introduction to description logics, and to argue why they are well-suited as ontology languages. In the remainder of the chapter we will put some flesh on this skeleton by providing more technical details with respect to the theory of description logics, and their relationship to state of the art ontology languages. More detail on these and other matters related to description logics can be found in [6]. Ontologies There have been many attempts to define what constitutes an ontology, per- haps the best known (at least amongst computer scientists) being due to Gruber: “an ontology is an explicit specification of a conceptualisation” [47].3 In this context, a conceptualisation means an abstract model of some aspect of the world, taking the form of a definition of the properties of important 3 This was later elaborated to “a formal specification of a shared conceptualisation” [21]. -
Proceedings of the 11Th International Workshop on Ontology
Proceedings of the 11th International Workshop on Ontology Matching (OM-2016) Pavel Shvaiko, Jérôme Euzenat, Ernesto Jiménez-Ruiz, Michelle Cheatham, Oktie Hassanzadeh, Ryutaro Ichise To cite this version: Pavel Shvaiko, Jérôme Euzenat, Ernesto Jiménez-Ruiz, Michelle Cheatham, Oktie Hassanzadeh, et al.. Proceedings of the 11th International Workshop on Ontology Matching (OM-2016). Ontology matching workshop, Kobe, Japan. No commercial editor., pp.1-252, 2016. hal-01421835 HAL Id: hal-01421835 https://hal.inria.fr/hal-01421835 Submitted on 15 Jul 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Ontology Matching OM-2016 Proceedings of the ISWC Workshop Introduction Ontology matching1 is a key interoperability enabler for the semantic web, as well as a useful tactic in some classical data integration tasks dealing with the semantic hetero- geneity problem. It takes ontologies as input and determines as output an alignment, that is, a set of correspondences between the semantically related entities of those on- tologies. These correspondences can be used for various tasks, such as ontology merg- ing, data translation, query answering or navigation on the web of data. Thus, matching ontologies enables the knowledge and data expressed in the matched ontologies to in- teroperate. -
Justification Oriented Proofs In
Justification Oriented Proofs in OWL Matthew Horridge, Bijan Parsia, and Ulrike Sattler School of Computer Science, The University of Manchester Abstract. Justifications — that is, minimal entailing subsets of an on- tology — are currently the dominant form of explanation provided by ontology engineering environments, especially those focused on the Web Ontology Language (OWL). Despite this, there are naturally occurring justifications that can be very difficult to understand. In essence, justifi- cations are merely the premises of a proof and, as such, do not articulate the (often non-obvious) reasoning which connect those premises with the conclusion. This paper presents justification oriented proofs as a poten- tial solution to this problem. 1 Introduction and Motivation Modern ontology development environments such as Prot´eg´e-4, the NeOn Toolkit, Swoop, and Top Braid Composer, allow users to request explanations for entail- ments (inferences) that they encounter when editing or browsing ontologies. In- deed, the provision of explanation generating functionality is generally seen as being a vital component in such tools. Over the last few years, justifications have become the dominant form of explanation in these tools. This paper examines justifications as a kind of explanation and highlights some problems with them. It then presents justification lemmatisation as a non-standard reasoning service, which can be used to augment a justification with intermediate inference steps, and gives rise to a structure known as a justification oriented proof. Ultimately, a justification oriented proof could be used as an input into some presentation de- vice to help a person step though a justification that is otherwise too difficult for them to understand. -
Curriculum Vitae
Curriculum vitae Thomas Andreas Meyer 25 August 2019 Address Room 312, Computer Science Building University of Cape Town University Avenue, Rondebosch Tel: +27 12 650 5519 e-mail: [email protected] WWW: http://cs.uct.ac.za/~tmeyer Biographical information Date of birth: 14 January 1964, Randburg, South Africa. Marital status: Married to Louise Leenen. We have two children. Citizenship: Australian and South African. Qualifications 1. PhD (Computer Science), University of South Africa, Pretoria, South Africa, 1999. 2. MSc (Computer Science), Rand Afrikaans University (now the University of Johan- nesburg), Johannesburg, South Africa, 1986. 3. BSc Honours (Computer Science) with distinction, Rand Afrikaans University (now the University of Johannesburg), Johannesburg, South Africa, 1985. 4. BSc (Computer Science, Mathematical Statistics), Rand Afrikaans University (now the University of Johannesburg), Johannesburg, South Africa, 1984. 1 Employment and positions held 1. July 2015 to date: Professor, Department of Computer Science, University of Cape Town, Cape Town, South Africa. 2. July 2015 to June 2020: Director, Centre for Artificial Intelligence Research (CAIR), CSIR, Pretoria, South Africa. 3. July 2015 to June 2020: UCT-CSIR Chair in Artificial Intelligence, University of Cape Town, Cape Town, South Africa. 4. August 2011 to June 2015: Chief Scientist, CSIR Meraka Institute, Pretoria, South Africa. 5. May 2011 to June 2015: Director of the UKZN/CSIR Meraka Centre for Artificial Intelligence Research, CSIR and University of KwaZulu-Natal, South Africa. 6. August 2007 to July 2011: Principal Researcher, CSIR Meraka Institute, Pretoria, South Africa. 7. August 2007 to June 2015: Research Group Leader of the Knowledge Representation and Reasoning group (KRR) at the CSIR Meraka Institute, Pretoria, South Africa. -
Data Curation+Process Curation^Data Integration+Science
BRIEFINGS IN BIOINFORMATICS. VOL 9. NO 6. 506^517 doi:10.1093/bib/bbn034 Advance Access publication December 6, 2008 Data curation 1 process curation^data integration 1 science Carole Goble, Robert Stevens, Duncan Hull, Katy Wolstencroft and Rodrigo Lopez Submitted: 16th May 2008; Received (in revised form): 25th July 2008 Abstract In bioinformatics, we are familiar with the idea of curated data as a prerequisite for data integration. We neglect, often to our cost, the curation and cataloguing of the processes that we use to integrate and analyse our data. Downloaded from https://academic.oup.com/bib/article/9/6/506/223646 by guest on 27 September 2021 Programmatic access to services, for data and processes, means that compositions of services can be made that represent the in silico experiments or processes that bioinformaticians perform. Data integration through workflows depends on being able to know what services exist and where to find those services. The large number of services and the operations they perform, their arbitrary naming and lack of documentation, however, mean that they can be difficult to use. The workflows themselves are composite processes that could be pooled and reused but only if they too can be found and understood. Thus appropriate curation, including semantic mark-up, would enable processes to be found, maintained and consequently used more easily.This broader view on semantic annotation is vital for full data integration that is necessary for the modern scientific analyses in biology.This article will brief the community on the current state of the art and the current challenges for process curation, both within and without the Life Sciences.