Table A2. Summary of Studies Assessing Retinally Induced
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12 Retina Gabriele K
299 12 Retina Gabriele K. Lang and Gerhard K. Lang 12.1 Basic Knowledge The retina is the innermost of three successive layers of the globe. It comprises two parts: ❖ A photoreceptive part (pars optica retinae), comprising the first nine of the 10 layers listed below. ❖ A nonreceptive part (pars caeca retinae) forming the epithelium of the cil- iary body and iris. The pars optica retinae merges with the pars ceca retinae at the ora serrata. Embryology: The retina develops from a diverticulum of the forebrain (proen- cephalon). Optic vesicles develop which then invaginate to form a double- walled bowl, the optic cup. The outer wall becomes the pigment epithelium, and the inner wall later differentiates into the nine layers of the retina. The retina remains linked to the forebrain throughout life through a structure known as the retinohypothalamic tract. Thickness of the retina (Fig. 12.1) Layers of the retina: Moving inward along the path of incident light, the individual layers of the retina are as follows (Fig. 12.2): 1. Inner limiting membrane (glial cell fibers separating the retina from the vitreous body). 2. Layer of optic nerve fibers (axons of the third neuron). 3. Layer of ganglion cells (cell nuclei of the multipolar ganglion cells of the third neuron; “data acquisition system”). 4. Inner plexiform layer (synapses between the axons of the second neuron and dendrites of the third neuron). 5. Inner nuclear layer (cell nuclei of the bipolar nerve cells of the second neuron, horizontal cells, and amacrine cells). 6. Outer plexiform layer (synapses between the axons of the first neuron and dendrites of the second neuron). -
Localisation of Visual Hallucinations
BRITISH MEDICAL JOURNAL 16 JULY 1977 147 of hypothermia; the duration of cardiac arrest; and the disturbances of sleep or consciousness.4 Hallucinations may be promptness and correctness of treatment. Peterson's pessi- evoked by sensory deprivation, but other factors are usually mistic report from California,8 in which all 15 near-drowned present; thus the "black-patch" delirium that may follow children who had fits, fixed dilated pupils, flaccidity, and loss cataract extraction in the elderly probably results from sensory Br Med J: first published as 10.1136/bmj.2.6080.147 on 16 July 1977. Downloaded from of pain sensation suffered severe anoxic encephalopathy, deprivation and mild senile brain changes and is more frequent may be explained by the high water temperatures there. In when hearing is also impaired.5 warm water the protective effect of hypothermia against brain Hallucinations may be due to focal lesions. Past experiences, damage would be missing. In contrast was the case described the quality of eidetic imagery, and psychodynamic "actors in Trondheim, Norway,9 in which a 5-year-old fell through influence the content of organic hallucinosis,6 and it would be ice in fresh water with an outside temperature of 10° below unwise to lean too heavily on the occurrence and nature of zero centigrade. He was in the water for 22 minutes and was hallucinosis in localising intracranial lesions. Visual hallucina- brought out apparently dead, with widely dilated pupils and tions are a relatively infrequent accompaniment oflesions ofthe bluish white skin. He was warmed up (the method was not calcarine cortex (Brodmann's area 17), which has few thalamo- described) and-despite the risks noted above-was given cortical connections; yet they may occur as a false-localising external cardiac massage without suffering ventricular symptom of frontal or subtentorial lesions. -
Visual Perception in Migraine: a Narrative Review
vision Review Visual Perception in Migraine: A Narrative Review Nouchine Hadjikhani 1,2,* and Maurice Vincent 3 1 Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA 2 Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, 41119 Gothenburg, Sweden 3 Eli Lilly and Company, Indianapolis, IN 46285, USA; [email protected] * Correspondence: [email protected]; Tel.: +1-617-724-5625 Abstract: Migraine, the most frequent neurological ailment, affects visual processing during and between attacks. Most visual disturbances associated with migraine can be explained by increased neural hyperexcitability, as suggested by clinical, physiological and neuroimaging evidence. Here, we review how simple (e.g., patterns, color) visual functions can be affected in patients with migraine, describe the different complex manifestations of the so-called Alice in Wonderland Syndrome, and discuss how visual stimuli can trigger migraine attacks. We also reinforce the importance of a thorough, proactive examination of visual function in people with migraine. Keywords: migraine aura; vision; Alice in Wonderland Syndrome 1. Introduction Vision consumes a substantial portion of brain processing in humans. Migraine, the most frequent neurological ailment, affects vision more than any other cerebral function, both during and between attacks. Visual experiences in patients with migraine vary vastly in nature, extent and intensity, suggesting that migraine affects the central nervous system (CNS) anatomically and functionally in many different ways, thereby disrupting Citation: Hadjikhani, N.; Vincent, M. several components of visual processing. Migraine visual symptoms are simple (positive or Visual Perception in Migraine: A Narrative Review. Vision 2021, 5, 20. negative), or complex, which involve larger and more elaborate vision disturbances, such https://doi.org/10.3390/vision5020020 as the perception of fortification spectra and other illusions [1]. -
The Visual Performance and Metamorphopsia of Patients with Macular Holes
CLINICAL SCIENCES The Visual Performance and Metamorphopsia of Patients With Macular Holes Yoshihiro Saito, MD; Yoshiko Hirata, MD; Atsushi Hayashi, MD; Takashi Fujikado, MD; Masahito Ohji, MD; Yasuo Tano, MD Background: Most patients attain better visual acuity divided the subjective changes into 2 types of metamor- with the elimination of metamorphopsia after success- phopsia; of the 54 eyes, pincushion distortion (bowed ful closure of a macular hole (MH) by vitrectomy. toward the center) was found in 33 (61%), and unpat- terned distortion (no specific pattern) was found in 21 Objective: To determine the presurgical visual func- (39%). Pincushion distortion was significantly associ- tion of eyes with an MH. ated with an MH of shorter duration (#6 months) (P = .03) and an early stage (stage 2) of MH formation Methods: We examined 54 eyes of 51 patients with an (P = .02). A scotoma was hard to detect, and patients had idiopathic MH using the Amsler chart. We evaluated difficulty describing their scotomata and distortions. In the types of subjective metamorphopsia and compared the montage test, patients with early MHs chose por- them with the clinical factors associated with MHs. In a traits modified with a pincushion type of distortion. prospective study, we performed a montage test on a separate group of 16 patients with unilateral idiopathic Conclusions: We found concentric pincushion meta- MHs. The patients were asked to choose, while viewing morphopsia without subjective scotomata, which we sug- with their better eye, the computer-modified picture gest arises from an eccentric displacement of the photo- that best matched the unmodified image seen by the eye receptors. -
Cataract Surgery and Diplopia
…AFTER CATARACT SURGERY Lionel Kowal RVEEH Melbourne חננו מאתך דעה בינה והשכל DISTORTION Everything in my talk is distorted by selection bias I don‟t do cataract surgery. I don‟t see the numerous happy pts that you produce I see a small Array of pts with imperfect outcomes that may /not be due to the cataract surgery DIPLOPIA AFTER CATARACT SURGERY ‘Old’ reasons ‘New’ reasons : Normal or near- normal muscle function: usually ≥1 ‘minor’ stresses on sensory & motor fusion Inf Rectus contracture after -- Anisometropia: Monovision & -caine damage Aniseikonia Other muscles damaged by -caine Metamorphopsia 2ary to macular disease Incidental 4ths and occult Minor acquired motility changes Graves‟ Ophthalmopathy of the elderly: Sagging eye uncovered by cataract surgery muscles Old, Rare & largely forgotten Other sensory issues: Big Amblyopia: fixation switch difference in contrast between Hiemann Bielschowsky images, large field defects. „OLD‟ REASONS : -CAINE TOXICITY IS IT A PERI- OR RETRO- BULBAR? If you add an EMG monitor to your injecting needle, whether you think you are doing a Retro- or Peri- Bulbar, you are IN the inf rectus ~ ½ of the time* *Elsas, Scott „OLD‟ REASONS : -CAINE TOXICITY CAN BE ANY MUSCLE, USU IR, ESP. LIR Day 1: LIR paresis : left hyper, restricted L depression, diplopia : everyone anxious ≤1% Day 7-10: diplopia goes : everyone happy Week 2+: LIR fibrosis begins - diplopia returns : left hypo, vertical & torsional diplopia, restricted L elevation: everyone upset 0.1-0.2% Hardly ever gets better Spontaneous recovery from inferior rectus contracture (consecutive hypotropia) following local anesthetic injury. Sutherland S, Kowal L. Binocul Vis Strabismus Q. -
Care of the Patient with Accommodative and Vergence Dysfunction
OPTOMETRIC CLINICAL PRACTICE GUIDELINE Care of the Patient with Accommodative and Vergence Dysfunction OPTOMETRY: THE PRIMARY EYE CARE PROFESSION Doctors of optometry are independent primary health care providers who examine, diagnose, treat, and manage diseases and disorders of the visual system, the eye, and associated structures as well as diagnose related systemic conditions. Optometrists provide more than two-thirds of the primary eye care services in the United States. They are more widely distributed geographically than other eye care providers and are readily accessible for the delivery of eye and vision care services. There are approximately 36,000 full-time-equivalent doctors of optometry currently in practice in the United States. Optometrists practice in more than 6,500 communities across the United States, serving as the sole primary eye care providers in more than 3,500 communities. The mission of the profession of optometry is to fulfill the vision and eye care needs of the public through clinical care, research, and education, all of which enhance the quality of life. OPTOMETRIC CLINICAL PRACTICE GUIDELINE CARE OF THE PATIENT WITH ACCOMMODATIVE AND VERGENCE DYSFUNCTION Reference Guide for Clinicians Prepared by the American Optometric Association Consensus Panel on Care of the Patient with Accommodative and Vergence Dysfunction: Jeffrey S. Cooper, M.S., O.D., Principal Author Carole R. Burns, O.D. Susan A. Cotter, O.D. Kent M. Daum, O.D., Ph.D. John R. Griffin, M.S., O.D. Mitchell M. Scheiman, O.D. Revised by: Jeffrey S. Cooper, M.S., O.D. December 2010 Reviewed by the AOA Clinical Guidelines Coordinating Committee: David A. -
Refractive Errors
Refractive Errors - Epidemiology & Risk Factors (("refractive errors/epidemiology"[MAJR:noexp]) OR ("refractive errors/ethnology"[MAJR:noexp]) OR (hyperopia/epidemiology[MAJR:noexp]) OR (hyperopia/ethnology[MAJR:noexp]) OR (myopia/epidemiology[MAJR:noexp]) OR (myopia/ethnology[MAJR:noexp]) OR (astigmatism/epidemiology[MAJR:noexp]) OR (astigmatism/ethnology[MAJR:noexp]) OR (presbyopia/epidemiology[MAJR:noexp]) OR (presbyopia/ethnology[MAJR:noexp])) ((Refractive Errors[MAJR:noexp]) OR (Hyperopia[MAJR:noexp]) OR (Myopia[MAJR:noexp]) OR (Astigmatism[MAJR:noexp]) OR (Presbyopia[MAJR:noexp])) AND (Prevalence[MeSH Terms) ((Refractive Errors[MAJR:noexp]) OR (Hyperopia[MAJR:noexp]) OR (Myopia[MAJR:noexp]) OR (Astigmatism[MAJR:noexp]) OR (Presbyopia[MAJR:noexp])) AND (Risk Factors[MeSH Terms]) (("myopia/epidemiology"[MeSH Terms]) OR (("myopia"[MeSH Terms]) AND ("risk factors"[MeSH Terms]))) AND ((reading[tiab]) OR (near work[tiab]) OR (nearwork[tiab]) OR (cylinder power[tiab]) OR (optical power[tiab]) OR (accommodation[tiab])) (refractive error*[tiab] OR hyperopia[tiab] OR myopia[tiab] OR astigmatism[tiab] OR presbyopia[tiab]) AND (epidemiolog*[tiab] OR ethnolog*[tiab] OR prevalen*[tiab] OR risk factor*[tiab]) (myopia[tiab]) AND (reading[tiab] OR nearwork[tiab] OR near work[tiab]) Diagnosis – Reproducibility of Results ("refractive errors/diagnosis"[MAJR]) AND ("reproducibility of results"[MeSH Terms]) (refractive error*[tiab] OR hyperopia[tiab] OR myopia[tiab] OR astigmatism[tiab] OR presbyopia[tiab]) AND (diagnos*[tiab] OR reproducib*[tiab]) -
Handbook of EEG INTERPRETATION This Page Intentionally Left Blank Handbook of EEG INTERPRETATION
Handbook of EEG INTERPRETATION This page intentionally left blank Handbook of EEG INTERPRETATION William O. Tatum, IV, DO Section Chief, Department of Neurology, Tampa General Hospital Clinical Professor, Department of Neurology, University of South Florida Tampa, Florida Aatif M. Husain, MD Associate Professor, Department of Medicine (Neurology), Duke University Medical Center Director, Neurodiagnostic Center, Veterans Affairs Medical Center Durham, North Carolina Selim R. Benbadis, MD Director, Comprehensive Epilepsy Program, Tampa General Hospital Professor, Departments of Neurology and Neurosurgery, University of South Florida Tampa, Florida Peter W. Kaplan, MB, FRCP Director, Epilepsy and EEG, Johns Hopkins Bayview Medical Center Professor, Department of Neurology, Johns Hopkins University School of Medicine Baltimore, Maryland Acquisitions Editor: R. Craig Percy Developmental Editor: Richard Johnson Cover Designer: Steve Pisano Indexer: Joann Woy Compositor: Patricia Wallenburg Printer: Victor Graphics Visit our website at www.demosmedpub.com © 2008 Demos Medical Publishing, LLC. All rights reserved. This book is pro- tected by copyright. No part of it may be reproduced, stored in a retrieval sys- tem, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Library of Congress Cataloging-in-Publication Data Handbook of EEG interpretation / William O. Tatum IV ... [et al.]. p. ; cm. Includes bibliographical references and index. ISBN-13: 978-1-933864-11-2 (pbk. : alk. paper) ISBN-10: 1-933864-11-7 (pbk. : alk. paper) 1. Electroencephalography—Handbooks, manuals, etc. I. Tatum, William O. [DNLM: 1. Electroencephalography—methods—Handbooks. WL 39 H23657 2007] RC386.6.E43H36 2007 616.8'047547—dc22 2007022376 Medicine is an ever-changing science undergoing continual development. -
Association of British Dispensing Opticians Heads You Win, Tails
Agenda Heads You Win, Tails You Lose • The correction of ametropia • Magnification, retinal image size, visual Association of British The Optical Advantages and acuity Disadvantages of Spectacle Dispensing Opticians • Field of view Lenses and Contact lenses • Accommodation and convergence 2014 Conference Andrew Keirl • Binocular vision and anisometropia Kenilworth Optometrist and Dispensing Optician • Presbyopia. 1 2 3 Spectacle lenses Contact lenses Introduction • Refractive errors that can be corrected • Refractive errors that can be corrected using • Patients often change from a spectacle to a using spectacle lenses: contact lenses: contact lens correction and vice versa – myopia – myopia • Both modes of correction are usually effective – hypermetropia in producing in-focus retinal images – hypermetropia • apparent size of the eyes and surround in both cases • There are of course some differences – astigmatism – astigmatism between modes, most of which are • not so good with irregular corneas • better for irregular corneas associated with the position of the correction. – presbyopia – presbyopia • Some binocular vision problems are • Binocular vision problems are difficult to manage using contact lenses. easily managed using spectacle lenses. 4 5 6 The correction of ametropia using Effectivity contact lenses • A distance correction will form an image • Hydrogel contact lenses at the far point of the eye – when a hydrogel contact lens is fitted to an eye, The Correction of Ametropia the lens “drapes” to fit the cornea • Due to the vertex distance this far point – this implies that the tear lens formed between the will lie at slightly different distances from contact lens and the cornea should have zero the two types of correcting lens power and the ametropia is corrected by the BVP of the contact lens – the powers of the spectacle lens and the – not always the case but usually assumed in contact lens required to correct a particular practice eye will therefore be different. -
Vitreomacular Traction Syndrome
RETINA HEALTH SERIES | Facts from the ASRS The Foundation American Society of Retina Specialists Committed to improving the quality of life of all people with retinal disease. Vitreomacular Traction Syndrome SYMPTOMS IN DETAIL The vitreous humor is a transparent, gel-like material that fills the space within the eye between the lens and The most common symptoms the retina. The vitreous is encapsulated in a thin shell experienced by patients with VMT syndrome are: called the vitreous cortex, and the cortex in young, healthy • Decreased sharpness of vision eyes is usually sealed to the retina. • Photopsia, when a person sees flashes of light in the eye As the eye ages, or in certain pathologic conditions, the vitreous cortex can • Micropsia, when objects appear pull away from the retina, leading to a condition known as posterior vitreous smaller than their actual size detachment (PVD). This detachment usually occurs as part of the normal • Metamorphopsia, when vision aging process. is distorted to make a grid of There are instances where a PVD is incomplete, leaving the vitreous straight lines appear wavy partially attached to the retina, and causing tractional (pulling) forces that or blank can cause anatomical damage. The resulting condition is called vitreomacular Some of these symptoms can be traction (VMT) syndrome. mild and develop slowly; however, VMT syndrome can lead to different maculopathies or disorders in the chronic tractional effects can macular area (at the center of the retina), such as full- or partial-thickness lead to continued visual loss macular holes, epiretinal membranes, and cystoid macular edema. These if left untreated. -
SHAW-Lens-Book.Pdf
THE LATEST ADVANCEMENT IN BINOCULAR VISION Aniseikonia WITH OPHTHALMIC Solved LENSES. EXPLORING ITS IMPACT ON PATIENT COMFORT AND VISION GET IT WORKING FOR YOU OD 03 Table of Contents “Majority of patients have a wow experience and said it’s the best lens they’ve ever worn.” Shaw Lens Inc. Clinical trials and research indicate that A Shajani, OD, BC Solving aniseikonia is the single most important thing ........................................4 spectacle-induced aniseikonia is a principal cause Why is dynamic aniseikonia so important? .....................................................5 of patient discomfort with eyeglasses. There are Symptoms ...............................................................................................6 Binocular Lens Design ..................................................................................7 no norms for tolerance to aniseikonia. This book Differentiate your practice ............................................................................9 Love at First Sight Guarantee ......................................................................11 contains real-life case summaries that demonstrate When to use the SHAW lens ......................................................................12 how solving aniseikonia can dramatically improve Case Summaries SHAW lens NO PATCH amblyopia treatment .........................................13 a patient’s experience with glasses. Amblyopia – Straight-eye amblyopia with monocular hyperopia .............................14 Amblyopia – Adult refractive -
Localizing and Lateralizing Value of Epileptic Symptoms in Temporal Lobe Epilepsy
Localizing and Lateralizing Value of Epileptic Symptoms in Temporal Lobe Epilepsy Jean-Marc Saint-Hilaire and Mary Anne Lee ABSTRACT: The symptoms and signs associated with all stages of a temporal lobe seizure may be helpful in determining both the localization and lateralization of seizure onset. Auras, when present, may be very suggestive of temporal lobe onset and may further localize to a mesiobasal or lateral temporal lobe site of onset. During the ictus, automatisms and motor phenomena may be highly indicative of temporal lobe seizure activity and may even help lateralize the discharge. In the post-ictal period, motor paresis and aphasia are helpful in lateralization. Video E.E.G. data has provided extensive information on the utility of ictal symptomatology in seizure localization. Thus, the seizure semiology provides important adjunctive information in evaluating patients for epilepsy surgery and should be concordant with information obtained from ictal EEG, neuroimaging and neuropsychology. RÉSUMÉ: La valeur des symptômes épileptiques pour la localisation et la latéralisation dans l'épilepsie temporale. Les symptômes et les signes associés à tous les stades d'une crise temporale peuvent aider à déterminer la localisation et la latéralisation du site de déclenchement de la crise. L'aura, quand elle est présente, peut être très suggestive d'un début temporal et peut localiser de façon plus précise le site de déclenchement de la crise. Pendant la crise, les automatismes et les phénomènes moteurs peuvent être hautement indicateurs d'une activité ictale temporale et peuvent même aider à latéraliser la décharge. Dans la période post-ictale, la parésie motrice et l'aphasie peuvent aider à la latéralisation.