8th Meeting of France Chairs Thursday, 5th June 10.25–10.40 Ľudmila Okruhlicová (Slovakia) - New EU Members Opening ceremony Modulation of connexin-43 with omega-3 fatty acids in the Venue: Manggha Centre, 26 Konopnickiej aorta of hypertensive and hypertriglyceridemic rats 16th JMRC Symposium Stefan Chłopicki () 10.40–11.20 Coffee Break 17.00–17.10 Welcome adresses th th Ramaroson Andriantsitohaina (France) 5 - 7 June, Kraków, Poland 17.10–17.45 Opening Lecture Endothelial inflammation (part two) Guy Vassort (France) Introduction Chairs: Andrzej Szczeklik (Poland), Marie Novaková Venue: Polish Academy of Arts Scientific Programme Committee Bohuslav Ošťádal (Czech Republic) (Czech Republic) and Sciences (PAU), 17 Sławkowska The past, the present and the future of experimental research Ramaroson Andriantsitohaina (France) on myocardial infarction 11.20–11.45 Claude Delcayre (France) 17.45–18.15 Concertino Aldosterone effects on coronary function Stefan Chłopicki (Poland) 18.15–21.00 Get–Together–Party 11.45–12.00 Frédéric Jaisser (France) (Poland) Role of endothelin in blood pressure increase induced by Friday, 6th June targeted MR overexpression in the endothelium Aleksander Koj (Poland) Venue: PAU, 17 Sławkowska 12.00–12.25 Francisco Perez Vizcaino (Spain) Jack McGiff (USA) Flavonoids and endothelial dysfunction 12.25–12.50 Stefan Chłopicki (Poland) Endothelial inflammation (part one) Marie Nováková (Czech Republic) 1-Methylnicotinamide in vascular protection Chairs: Bohuslav Ošťádal (Czech Republic) 12.50–13.05 Agnieszka Jaźwa (Poland) Zoltán Papp (Hungary) Barbara Malinowska (Poland) AAV-mediated VEGF165 and FGF-4 gene transfer for the Táňa Ravingerová (Slovakia) treatment of hind limb ischemia 08.30–08.55 François Mach () Andrzej Szczeklik (Poland) Pharmacology of endocannabinoid system in atherosclerosis 13.05 - 14.30 Lunch Adam Szewczyk (Poland) 08.55–9.10 Attila Tóth (Hungary) Transactivation of arachidonic acid pathway by anandamide 14.30–16.30 Poster Session part one Guy Vassort (France) affects microvascular autoregulation 9.10–9.35 Charlotte Lawson (UK) Endothelial Inflammation (part three) ICAM-1 signalling in endothelial cells Chairs: Táňa Ravingerová (Slovakia), Włodzimierz Organising Committee Buczko (Poland) 9.35–10.00 Andreas Daiber (Germany) Nitrate tolerance as a model of vascular dysfunction: 16.30–16.55 Zsolt Bagi (Hungary) Roles for mitochondrial aldehyde dehydrogenase and New Frontiers Maria Chechlińska Coronary microvascular adaptation in metabolic syndrome mitochondrial oxidative stress in Cardiovascular Research Dominika Piszczek 16.55–17.10 Joanna Soin (Poland) 10.00–10.25 Ramaroson Andriantsitohaina (France) Overexpression of CD39/nucleoside triphosphate Microparticles and vascular inflammation diphosphohydrolase-1 prevents restenosis after angioplasty? 17.10–17.35 Ulf Simonsen (Denmark) 08.55–09.10 Reinis Vilskersts (Latvia) 12.45–13.10 Tomáš Šimůnek (Czech Republic) Main Organiser: Endothelial cell signalling transduction and nitric oxide- Metabolic, vascular and cardioprotective effects of Anthracycline-induced cardiotoxicity: Studies of the role of mediated vasodilatation mildronate in experimental model of type 2 diabetic oxidative stress and free cellular iron 17.35–18.00 Oľga Pecháňová (Slovakia) Goto-Kakizaki rats 13.10–13.25 Jan Neckář (Czech Republic) Soluble epoxide hydrolase inhibitor improves cardiac Mechanisms of L-NAME-induced hypertension: peripheral 09.10–09.35 Sean Davidson (UK) ischemic tolerance in Ren-2 transgenic rats and central regulations Myocardial mitochondria in ischaemia and 18.00–18.15 Krystyna Pawlak (Poland) reperfusion injury 13.25–14.45 Lunch Kynurenine and its metabolites are associated with 09.35–09.50 Rostyslav Stoika (Ukraine) oxidative stress markers and prevalence of cardiovascular Differential effects of alkaloids towards mitochondria 14.45–16.45 Poster Session part two disease in end-stage renal disease patients 09.50–10.05 Vilma Borutaite (Lithuania) Co-organiser: 18.15–18.30 Attila Ziegelhöffer (Slovakia) The redox state of cytochrome c regulates ischemia- Closing lecture Quo vadis oxidative stress? Could we be still really sure that induced apoptosis in perfused heart Chairs: Ramaroson Andriantsitohaina (France) we are always dealing with the same phenomenon? 10.05–10.30 Renée Ventura-Clapier (France) Stefan Chłopicki (Poland) Mitochondrial dysfunction in heart failure 16.45–17.15 Randy Spraque (USA) Venue: Pugets’ Palace, 13 Starowiślna Do erythrocytes contribute to the vascular disease of 20.00–20.30 Evening Lecture 10.30–11.15 Coffee Break diabetes? Andrzej Szczeklik (Poland) Introduction 17.15–17.35 Closing notes, poster prize Main Sponsor: John C. McGiff (USA) Myocardial contractility from normal to failure Philosophy of medical experiments Chairs: Zoltán Papp (Hungary), Olivier Cazorla 20.30–22.30 Dinner (France) Venue: Historical Museum, 35 Market Square 19.30–20.00 Evening lecture 11.15–11.40 Luc Hittinger (France) Saturday, 7th June Giuseppe Nistico (Italy) How to progress in the understanding of diastolic Sponsors: Venue: PAU, 17 Sławkowska From magic to experimental heart failure 20.00–21.00 Glass–of–Wine Reception 11.40–12.05 Attila Borbély (Hungary) Mitochondria and cardiovascular pathology Molecular determinants of diastolic heart failure (co-organised with Mito-NET) 12.05–12.20 Lara Khouzami (France)

Chairs: Adam Szewczyk (Poland), Józef Dulak (Poland) Benefits of N-acetylcysteine treatment in heart failing Lectures - 20 min. plus 5 min. discussion, Polska Akademia Umiejętności (PAU) LMNAH222P/H222P mouse reply on harmful Short presentation - 10 min. plus 5 min. discussion, 08.30–08.55 Fabio di Lisa (Italy) processes blunting and protective response preservation Poster sessions will be held at the PAU’s interior yard in 12.20–12.45 Frank Lezoualc’h (France) Mitochondria and vascular pathology Epac – from hypertrophy to failure the venue. www.jmrc.org.pl