Author’s Accepted Manuscript

Evaluation of the p53 and Thioredoxin reductase in sperm from asthenozoospermic males in comparison to normozoospermic males

Mohmmad-nabi Moradi, Karimi, Khodadadi, Iraj Amiri, Manoochehr Karami, Massoud Saidijam, Akram Vatannejad, Heidar Tavilani www.elsevier.com

PII: S0891-5849(17)31290-X DOI: https://doi.org/10.1016/j.freeradbiomed.2017.12.038 Reference: FRB13573 To appear in: Free Radical Biology and Medicine Received date: 1 December 2017 Revised date: 26 December 2017 Accepted date: 29 December 2017 Cite this article as: Mohmmad-nabi Moradi, Jamshid Karimi, Iraj Khodadadi, Iraj Amiri, Manoochehr Karami, Massoud Saidijam, Akram Vatannejad and Heidar Tavilani, Evaluation of the p53 and Thioredoxin reductase in sperm from asthenozoospermic males in comparison to normozoospermic males, Free Radical Biology and Medicine, https://doi.org/10.1016/j.freeradbiomed.2017.12.038 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Evaluation of the p53 and Thioredoxin reductase in sperm from asthenozoospermic males in comparison to normozoospermic males Mohmmad-nabi Moradi1, Jamshid Karimi1, Iraj Khodadadi1, Iraj Amiri2, Manoochehr

Karami3, Massoud Saidijam4, Akram Vatannejad5,6, Heidar Tavilani7*

1Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan,

Iran

2Endometrium and Endometriosis Research Center, Hamadan University of Medical

Sciences, Hamadan,

3Modeling of Non-Communicable Diseases Research Center, Department of Biostatistics and

Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan,

Iran

4Research Center for Molecular Medicine, Hamadan University of Medical Sciences,

Hamadan, Iran

5Department of Biochemistry, School of Medicine, Tehran, University of Medical Science

Tehran Iran

6Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and

Dietetics, Tehran University of Medical Sciences, Tehran, Iran

7Urology & Nephrology Research Center, Hamadan University of Medical Sciences,

Hamadan, Iran.

Correspondence: Heidar Tavilani, Urology & Nephrology Research Center, Hamadan

University of Medical Sciences, Shaheed Fahmideh Ave., Hamadan, Iran, Tel: +98-

8138380462, Fax: +98-8138380208, E-mail: [email protected], [email protected]