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Longevity Studies in Genomeutwin
Longevity Studies in GenomEUtwin Axel Skytthe1, Nancy L. Pedersen3, Jaakko Kaprio4, Maria Antonietta Stazi5, Jacob v.B. Hjelmborg1, Ivan Iachine2, James W. Vaupel1, and Kaare Christensen1 1 The Danish Twin Registry, Epidemiology Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark 2 The Department of Statistics, Institute of Public Health, University of Southern Denmark, Odense, Denmark 3 The Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden 4 The Finnish Twin Cohort Study, University of Helsinki, Finland 5 The Italian Twin Registry, Instituto Superiore di Sanità, Roma, Italia revious twin studies have indicated that approximately 25% A large ongoing research effort is underway to identify Pof the variation in life span can be attributed to genetic the genetic, environmental, and behavioral determinants of factors and recent studies have also suggested a moderate extreme survival by comparing centenarians with younger clustering of extreme longevity within families. Here we discuss various definitions of extreme longevity and some ana- cohorts (association studies). However, such studies suffer lytical approaches with special attention to the challenges due from the lack of an appropriate comparison group as to censored data. Lexis diagrams are provided for the Danish, cohort specific characteristics may confound the compari- Dutch, Finnish, Italian, Norwegian, and Swedish Twin registries son between the centenarians and younger cohorts. To date, hereby outlining possibilities for longevity studies within only one common polymorphism, namely Apo-E e2 GenomEUtwin. We extend previous analyses of lifespan for [ARG158CYS] of the ApoE e2/e3/e4 polymorphism, has the Danish 1870–1900 twin cohorts to include the new consistently been shown to be associated with survival until 1901–1910 cohorts, which are consistent with the previous extreme ages (Gerdes et al., 2000). -
2005 Living to 100 and Beyond Monograph: IDL, the International
IDL, the International Database on Longevity Jean-Marie Robine Amandine Cournil University of Montpellier, France Jutta Gampe Max Planck Institute for Demographic Research, Rostock, Germany James W. Vaupel Max Planck Institute for Demographic Research, Rostock, Germany Presented at The Living to 100 and Beyond Symposium Sponsored by the Society of Actuaries Orlando, Fla. January 12–14, 2005 Copyright 2005 by the Society of Actuaries. All rights reserved by the Society of Actuaries. Permission is granted to make brief excerpts for a published review. Permission is also granted to make limited numbers of copies of items in this monograph for personal, internal, classroom or other instructional use, on condition that the foregoing copyright notice is used so as to give reasonable notice of the Society's copyright. This consent for free limited copying without prior consent of the Society does not extend to making copies for general distribution, for advertising or promotional purposes, for inclusion in new collective works or for resale. 1 Abstract Since the first symposium, "Living to 100 and Beyond: Survival at Advanced Ages," held in 2002, a collaborative effort has been made to assemble an international database on longevity, gathering validated longevity records for people having reached at least their 110th birthday. More than 15 countries, including the United States of America, Canada and Japan, along with European countries, have been participating in this "supercentenarian" project. Collaboration with national statistical offices or health departments has allowed the investigators to obtain complete lists of alleged supercentenarians in most countries. Different validation processes were then undertaken by the participating teams. -
The Documentary Handbook
The Documentary Handbook The Documentary Handbook takes a thematic approach to documentary, including chapters on the many myriad forms we watch today – from the cinematic releases of Michael Moore to low-budget internet efforts like Video Nation, from ‘shock docs’ to reality television. The Documentary Handbook is a critical introduction to the documentary film, its theory and changing practices. The book charts the evolution of the documentary from screen art to core television genre, its metamorphosis into many different types of factual TV programmes and its current emergence in forms of new media. It analyses those pathways and the transformation of means of production through economic, technical and editorial changes. The Documentary Handbook explains the documentary process, skills and job specifica- tions for everyone from industry entrants to senior personnel, and shows how the industrial evolution of television has relocated the powers and principles of decision-making. Through the use of professional ‘expert briefings’ it gives practical pointers about programme- making, from researching, developing and pitching programme ideas to their production and delivery through a fast-evolving multi-platform universe. Peter Lee-Wright is a documentary filmmaker with 30 years’ experience working for the BBC and Channel 4. He is currently Senior Lecturer in Media and Communications at Goldsmiths, University of London. His most recent writing includes critical overviews of sports documentary and trade union documentary in Encyclopedia of the Documentary Film (2005) and analysis of the changes taking place in multimedia news, notably in New Media, Old News (edited by Natalie Fenton, 2009). Media Practice Edited by James Curran, Goldsmiths, University of London The Media Practice handbooks are comprehensive resource books for students of media and journalism, and for anyone planning a career as a media professional. -
FRANKFURT 2020 CORNERSTONE, EBURY, PENGUIN GENERAL, PENGUIN PRESS PENGUIN RIGHTS DEPARTMENT Cornerstone | Ebury | Penguin General | Penguin Press
TRANSLATION RIGHTS GUIDE FRANKFURT 2020 CORNERSTONE, EBURY, PENGUIN GENERAL, PENGUIN PRESS PENGUIN RIGHTS DEPARTMENT Cornerstone | Ebury | Penguin General | Penguin Press Chantal Noel, Group Rights Director Email: [email protected] Sarah Scarlett, Adult Rights Director USA & Canada (Ebury & Transworld) Email: [email protected] Amelia Evans, Rights Director USA & Canada (Cornerstone, Penguin Press & Penguin General) Email: [email protected] Monique Corless, Head of Translation Germany, France & Netherlands Email: mcorless @penguinrandomhouse.co.uk Ann Katrin Ziser, Senior Rights Manager Spain, Portugal, Brazil, Italy & China Email: [email protected] Elizabeth Brandon, Rights Manager Norway, Sweden, Denmark, Finland, Iceland, Japan, Korea, Taiwan & Poland Email: [email protected] Catherine Turner, Senior Rights Executive Greece, Turkey, Russia, Romania, Hungary, Czech Republic & Slovakia Email: [email protected] Annamika Singh, Rights Executive Ukraine, Estonia, Lithuania, Latvia, Bulgaria, Serbia, Macedonia, Albania, Malaysia, Indonesia, Vietnam, Thailand, Slovenia, Croatia, Arab World, Israel Large print, Audio & Hardcover Reprint Email: [email protected] Laura Milford, Rights Assistant Montenegro, Georgia, Armenia, Azerbaijan, Mongolia, Bosnia & Herzegovina Email: [email protected] Ralista Chorbadzhiyska, Rights Assistant 2nd Serial Email: [email protected] CONTENTS FICTION 11 SOCIAL SCIENCES -
IDL, the International Database on Longevity Jean-Marie Robine
IDL, the International Database on Longevity Jean-Marie Robine*, Jutta Gampe**, Amandine Cournil* and James Vaupel** *Health and Demography, INSERM, Montpellier, France, <[email protected]>; **Max Planck, Institute for Demographic Research, Rostock, Germany Abstract: Since the first symposium, “Living to 100 and Beyond: Survival at Advanced Ages” held in 2002, a collaborative effort has been made to assemble an international database on longevity, gathering validated longevity records for people having reached at least their 110th birthday. More than 15 countries, including the United States of America, Canada and Japan, along with European countries, have been participating in this Supercentenarian project. Collaboration with national statistical offices or health departments has allowed the investigators to obtain complete lists of alleged supercentenarians in most countries. Different validation processes are then undertaken by the participating teams. By March 2004, more than 500 validated records had been gathered. This paper first evaluates the quality of data according to several criteria, such as the country of residence or the validation process undertaken, and then provides an estimation of the mortality trajectory up to age 114. Introduction Although the Gompertz exponential model has for a long time been the prevailing method used to explain the increase in death rates in human populations, evidence indicates that the increase in the risks of death tends to decelerate at older ages (something that the Gompertz model does not account for). Different patterns of mortality deceleration have been proposed, ranging from a slower increase for the oldest of the old to a rapid decrease of mortality rates above a certain age (Vaupel et al, 1998; Thatcher, 1999). -
Requirements for the Degree
FREQUENCY OF USE AND SURVIVAL OF SELECTED STREET TREE TAD IN THREE WISCONSIN CITIES by Randall H. Miller A Thesis submitted in partial fulfillment of the requirements for the degree MASTER OF SCIENCE College of Natural Resources UNIVERSITY OF WISCONSIN Stevens Point, Wisconsin January 1989 APPROVED BY THE GRADUATE COMMITTEE OF: -~~~························· Committee Chairman Professor of Forestry Dr. Robert F1cckmann Professor of B]ology ✓-~:~ ~( (\ j .. -~~·----··-·-hJ~---·Dr. David Hillier ·-·······----·-- Professor of Biology ABSTRACT Planting records for Milwaukee, Naukesha, and Stevens Point Wisconsin were examined to determine frequency of taxa use. Records indicated homogeneity emphasizing Norway maple, green ash, littleleaf linden and honeylocust. Homogeneity was augmented by reliance on a few cultivars, especially 'Emerald Queen', 'Schwedler' and 'Columnar' Norway maple and 'Marshall's Seedless' green ash. Connonly planted taxa: Norway maple, green ash, honeylocust, callery pear, English oak, Crimean linden and littleleaf linden were sampled and examined for survival in Milwaukee, Naukesha and Stevens Point, Nisconsin. A four year establishment period was indicated. It was generally independent of taxa but 'Autumn Purple',white ash nearly failed in Milwaukee, while honeylocust and green ash performed well in Naukesha. Cultivars of Norway maple did not perform well enough to justify their emphasis in planting records. Heavy traffic (over 15,000 cars per day) was found to reduce survival in Milwaukee. iii ACKNOWLEDGEMENTS I would like to acknowledge my co11111ittee chairman, Dr. Robert W. Miller, who provided advice throughout the project. Co11111ittee members Dr. David Hillier and Dr. Robert Freckmann read the manuscript and contributed helpful suggestions. Ken Ottman, supervisor Milwaukee Bureau of Forestry, and Dave Liska, Waukesha city forester provided access to records and knowledgeable co11111entary.