Rabbit Anti-Human SUMO2 Polyclonal antibody (DPABH-18095) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Immunogen SUMO2/3 fusion , sequence: MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFD GQPINETDTPAQLEMEDEDTIDVFQQQTGGVY (1-95 aa encoded by BC016775)

Isotype IgG

Source/Host Rabbit

Species Reactivity Human, Mouse

Purification Antigen affinity purification

Conjugate Unconjugated

Applications WB, IHC, IF, ELISA

Positive Control Apoptosised HeLa cells, Recombinant protein protein

Format Liquid

Size 50 uL; 100 uL

Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Preservative 0.02% Sodium Azide

Storage Store at -20°C. Aliquoting is unnecessary for -20°C storage.

BACKGROUND

Introduction This encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Keywords SUMO2; small ubiquitin-like modifier 2; HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; small ubiquitin-related modifier 2; sentrin 2; SMT3 homolog 2; ubiquitin-like protein SMT3A; ubiquitin- like protein SMT3B; SMT3 suppressor of mif two 3 homolog 2;

GENE INFORMATION

Entrez Gene ID 6613

UniProt ID P61956

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved