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Guide for Common Viral Diseases of Animals in Louisiana
Sampling and Testing Guide for Common Viral Diseases of Animals in Louisiana Please click on the species of interest: Cattle Deer and Small Ruminants The Louisiana Animal Swine Disease Diagnostic Horses Laboratory Dogs A service unit of the LSU School of Veterinary Medicine Adapted from Murphy, F.A., et al, Veterinary Virology, 3rd ed. Cats Academic Press, 1999. Compiled by Rob Poston Multi-species: Rabiesvirus DCN LADDL Guide for Common Viral Diseases v. B2 1 Cattle Please click on the principle system involvement Generalized viral diseases Respiratory viral diseases Enteric viral diseases Reproductive/neonatal viral diseases Viral infections affecting the skin Back to the Beginning DCN LADDL Guide for Common Viral Diseases v. B2 2 Deer and Small Ruminants Please click on the principle system involvement Generalized viral disease Respiratory viral disease Enteric viral diseases Reproductive/neonatal viral diseases Viral infections affecting the skin Back to the Beginning DCN LADDL Guide for Common Viral Diseases v. B2 3 Swine Please click on the principle system involvement Generalized viral diseases Respiratory viral diseases Enteric viral diseases Reproductive/neonatal viral diseases Viral infections affecting the skin Back to the Beginning DCN LADDL Guide for Common Viral Diseases v. B2 4 Horses Please click on the principle system involvement Generalized viral diseases Neurological viral diseases Respiratory viral diseases Enteric viral diseases Abortifacient/neonatal viral diseases Viral infections affecting the skin Back to the Beginning DCN LADDL Guide for Common Viral Diseases v. B2 5 Dogs Please click on the principle system involvement Generalized viral diseases Respiratory viral diseases Enteric viral diseases Reproductive/neonatal viral diseases Back to the Beginning DCN LADDL Guide for Common Viral Diseases v. -
Comparative Evolutionary and Phylogenomic Analysis of Avian Avulaviruses 1 to 20
Accepted Manuscript Comparative evolutionary and phylogenomic analysis of Avian avulaviruses 1 to 20 Aziz-ul-Rahman, Muhammad Munir, Muhammad Zubair Shabbir PII: S1055-7903(17)30947-8 DOI: https://doi.org/10.1016/j.ympev.2018.06.040 Reference: YMPEV 6223 To appear in: Molecular Phylogenetics and Evolution Received Date: 1 January 2018 Revised Date: 15 May 2018 Accepted Date: 25 June 2018 Please cite this article as: Aziz-ul-Rahman, Munir, M., Zubair Shabbir, M., Comparative evolutionary and phylogenomic analysis of Avian avulaviruses 1 to 20, Molecular Phylogenetics and Evolution (2018), doi: https:// doi.org/10.1016/j.ympev.2018.06.040 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Comparative evolutionary and phylogenomic analysis of Avian avulaviruses 1 to 20 Aziz-ul-Rahman1,3, Muhammad Munir2, Muhammad Zubair Shabbir3# 1Department of Microbiology University of Veterinary and Animal Sciences, Lahore 54600, Pakistan https://orcid.org/0000-0002-3342-4462 2Division of Biomedical and Life Sciences, Furness College, Lancaster University, Lancaster LA1 4YG United Kingdomhttps://orcid.org/0000-0003-4038-0370 3 Quality Operations Laboratory University of Veterinary and Animal Sciences 54600 Lahore, Pakistan https://orcid.org/0000-0002-3562-007X # Corresponding author: Muhammad Zubair Shabbir E. -
2020 Taxonomic Update for Phylum Negarnaviricota (Riboviria: Orthornavirae), Including the Large Orders Bunyavirales and Mononegavirales
Archives of Virology https://doi.org/10.1007/s00705-020-04731-2 VIROLOGY DIVISION NEWS 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales Jens H. Kuhn1 · Scott Adkins2 · Daniela Alioto3 · Sergey V. Alkhovsky4 · Gaya K. Amarasinghe5 · Simon J. Anthony6,7 · Tatjana Avšič‑Županc8 · María A. Ayllón9,10 · Justin Bahl11 · Anne Balkema‑Buschmann12 · Matthew J. Ballinger13 · Tomáš Bartonička14 · Christopher Basler15 · Sina Bavari16 · Martin Beer17 · Dennis A. Bente18 · Éric Bergeron19 · Brian H. Bird20 · Carol Blair21 · Kim R. Blasdell22 · Steven B. Bradfute23 · Rachel Breyta24 · Thomas Briese25 · Paul A. Brown26 · Ursula J. Buchholz27 · Michael J. Buchmeier28 · Alexander Bukreyev18,29 · Felicity Burt30 · Nihal Buzkan31 · Charles H. Calisher32 · Mengji Cao33,34 · Inmaculada Casas35 · John Chamberlain36 · Kartik Chandran37 · Rémi N. Charrel38 · Biao Chen39 · Michela Chiumenti40 · Il‑Ryong Choi41 · J. Christopher S. Clegg42 · Ian Crozier43 · John V. da Graça44 · Elena Dal Bó45 · Alberto M. R. Dávila46 · Juan Carlos de la Torre47 · Xavier de Lamballerie38 · Rik L. de Swart48 · Patrick L. Di Bello49 · Nicholas Di Paola50 · Francesco Di Serio40 · Ralf G. Dietzgen51 · Michele Digiaro52 · Valerian V. Dolja53 · Olga Dolnik54 · Michael A. Drebot55 · Jan Felix Drexler56 · Ralf Dürrwald57 · Lucie Dufkova58 · William G. Dundon59 · W. Paul Duprex60 · John M. Dye50 · Andrew J. Easton61 · Hideki Ebihara62 · Toufc Elbeaino63 · Koray Ergünay64 · Jorlan Fernandes195 · Anthony R. Fooks65 · Pierre B. H. Formenty66 · Leonie F. Forth17 · Ron A. M. Fouchier48 · Juliana Freitas‑Astúa67 · Selma Gago‑Zachert68,69 · George Fú Gāo70 · María Laura García71 · Adolfo García‑Sastre72 · Aura R. Garrison50 · Aiah Gbakima73 · Tracey Goldstein74 · Jean‑Paul J. Gonzalez75,76 · Anthony Grifths77 · Martin H. Groschup12 · Stephan Günther78 · Alexandro Guterres195 · Roy A. -
VMC 321: Systematic Veterinary Virology Retroviridae Retro: from Latin Retro,"Backwards”
VMC 321: Systematic Veterinary Virology Retroviridae Retro: from Latin retro,"backwards” - refers to the activity of reverse RETROVIRIDAE transcriptase and the transfer of genetic information from RNA to DNA. Retroviruses Viral RNA Viral DNA Viral mRNA, genome (integrated into host genome) Reverse (retro) transfer of genetic information Usually, well adapted to their hosts Endogenous retroviruses • RNA viruses • single stranded, positive sense, enveloped, icosahedral. • Distinguished from all other RNA viruses by presence of an unusual enzyme, reverse transcriptase. Retroviruses • Retro = reversal • RNA is serving as a template for DNA synthesis. • One genera of veterinary interest • Alpharetrovirus • • Family - Retroviridae • Subfamily - Orthoretrovirinae [Ortho: from Greek orthos"straight" • Genus -. Alpharetrovirus • Genus - Betaretrovirus Family- • Genus - Gammaretrovirus • Genus - Deltaretrovirus Retroviridae • Genus - Lentivirus [ Lenti: from Latin lentus, "slow“ ]. • Genus - Epsilonretrovirus • Subfamily - Spumaretrovirinae • Genus - Spumavirus Retroviridae • Subfamily • Orthoretrovirinae • Genus • Alpharetrovirus Alpharetrovirus • Species • Avian leukosis virus(ALV) • Rous sarcoma virus (RSV) • Avian myeloblastosis virus (AMV) • Fujinami sarcoma virus (FuSV) • ALVs have been divided into 10 envelope subgroups - A , B, C, D, E, F, G, H, I & J based on • host range Avian • receptor interference patterns • neutralization by antibodies leukosis- • subgroup A to E viruses have been divided into two groups sarcoma • Noncytopathic (A, C, and E) • Cytopathic (B and D) virus (ALV) • Cytopathic ALVs can cause a transient cytotoxicity in 30- 40% of the infected cells 1. The viral envelope formed from host cell membrane; contains 72 spiked knobs. 2. These consist of a transmembrane protein TM (gp 41), which is linked to surface protein SU (gp 120) that binds to a cell receptor during infection. 3. The virion has cone-shaped, icosahedral core, Structure containing the major capsid protein 4. -
Para Influenza Virus 3 Infection in Cattle and Small Ruminants in Sudan
Journal of Advanced Veterinary and Animal Research ISSN 2311-7710 (Electronic) http://doi.org/10.5455/ javar.2016.c160 September 2016 A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) Vol 3 No 3, Pages 236-241. Original Article Para influenza virus 3 infection in cattle and small ruminants in Sudan Intisar Kamil Saeed, Yahia Hassan Ali, Khalid Mohammed Taha, Nada ElAmin Mohammed, Yasir Mehdi Nouri, Baraa Ahmed Mohammed, Osama Ishag Mohammed, Salma Bushra Elmagboul and Fahad AlTayeb AlGhazali • Received: March 24, 2016 • Revised: April 26, 2016 • Accepted: April 29, 2016 • Published Online: May 2, 2016 AFFILIATIONS ABSTRACT Intisar Saeed Objective: This study was aimed at elucidating the association between Para Yahia Ali influenza virus 3 (PIV3) and respiratory infections in domestic ruminants in Baraa Ahmed Virology Department, Veterinary Research different areas of Sudan. Institute, P.O. Box 8067, Al Amarat, Materials and methods: During 2010-2013, five hundred sixty five lung samples Khartoum, Sudan. #Current address: with signs of pneumonia were collected from cattle (n=226), sheep (n=316) and Northern Border University, Faculty of Science and Arts, Rafha, Saudi Arabia. goats (n=23) from slaughter houses in different areas in Sudan. The existence of PIV3 antigen was screened in the collected samples using ELISA and Fluorescent Khalid Taha antibody technique. PIV3 genome was detected by PCR, and sequence analysis was Atbara Veterinary Research Laboratory, P.O. Box 121 Atbara, River Nile State, conducted. Sudan. Results: Positive results were found in 29 (12.8%) cattle, 31 (9.8%) sheep and 11 (47.8%) goat samples. All the studied areas showed positive results. -
How Influenza Virus Uses Host Cell Pathways During Uncoating
cells Review How Influenza Virus Uses Host Cell Pathways during Uncoating Etori Aguiar Moreira 1 , Yohei Yamauchi 2 and Patrick Matthias 1,3,* 1 Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland; [email protected] 2 Faculty of Life Sciences, School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK; [email protected] 3 Faculty of Sciences, University of Basel, 4031 Basel, Switzerland * Correspondence: [email protected] Abstract: Influenza is a zoonotic respiratory disease of major public health interest due to its pan- demic potential, and a threat to animals and the human population. The influenza A virus genome consists of eight single-stranded RNA segments sequestered within a protein capsid and a lipid bilayer envelope. During host cell entry, cellular cues contribute to viral conformational changes that promote critical events such as fusion with late endosomes, capsid uncoating and viral genome release into the cytosol. In this focused review, we concisely describe the virus infection cycle and highlight the recent findings of host cell pathways and cytosolic proteins that assist influenza uncoating during host cell entry. Keywords: influenza; capsid uncoating; HDAC6; ubiquitin; EPS8; TNPO1; pandemic; M1; virus– host interaction Citation: Moreira, E.A.; Yamauchi, Y.; Matthias, P. How Influenza Virus Uses Host Cell Pathways during 1. Introduction Uncoating. Cells 2021, 10, 1722. Viruses are microscopic parasites that, unable to self-replicate, subvert a host cell https://doi.org/10.3390/ for their replication and propagation. Despite their apparent simplicity, they can cause cells10071722 severe diseases and even pose pandemic threats [1–3]. -
Differential Features of Fusion Activation Within the Paramyxoviridae
viruses Review Differential Features of Fusion Activation within the Paramyxoviridae Kristopher D. Azarm and Benhur Lee * Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; [email protected] * Correspondence: [email protected]; Tel.: +1-212-241-2552 Received: 17 December 2019; Accepted: 29 January 2020; Published: 30 January 2020 Abstract: Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated. This regulation ensures entry will only initiate when the virion is in the vicinity of a target cell membrane. Here, we review recent structural and mechanistic studies to delineate the entry features that are shared and distinct amongst the Paramyxoviridae. In general, we observe overarching distinctions between the protein-using RBPs and the sialic acid- (SA-) using RBPs, including how their stalk domains differentially trigger F. Moreover, through sequence comparisons, we identify greater structural and functional conservation amongst the PMV fusion proteins, as compared to the RBPs. When examining the relative contributions to sequence conservation of the globular head versus stalk domains of the RBP, we observe that, for the protein-using PMVs, the stalk domains exhibit higher conservation and find the opposite trend is true for SA-using PMVs. A better understanding of conserved and distinct features that govern the entry of protein-using versus SA-using PMVs will inform the rational design of broader spectrum therapeutics that impede this process. Keywords: paramyxovirus; viral envelope proteins; type I fusion protein; henipavirus; virus entry; viral transmission; structure; rubulavirus; parainfluenza virus 1. -
Murdoch Research Repository
MURDOCH RESEARCH REPOSITORY This is the author’s final version of the work, as accepted for publication following peer review but without the publisher’s layout or pagination. The definitive version is available at http://dx.doi.org/10.1016/j.meegid.2012.04.022 Hyndman, T., Marschang, R.E., Wellehan, J.F.X. and Nicholls, P.K. (2012) Isolation and molecular identification of Sunshine virus, a novel paramyxovirus found in Australian snakes. Infection, Genetics and Evolution, 12 (7). pp. 1436-1446. http://researchrepository.murdoch.edu.au/10552/ Copyright: © 2012 Elsevier B.V. It is posted here for your personal use. No further distribution is permitted. Accepted Manuscript Isolation and molecular identification of sunshine virus, a novel paramyxovirus found in australian snakes Timothy H. Hyndman, Rachel E. Marschang, James F.X. Wellehan, Philip K. Nicholls PII: S1567-1348(12)00168-2 DOI: http://dx.doi.org/10.1016/j.meegid.2012.04.022 Reference: MEEGID 1292 To appear in: Infection, Genetics and Evolution Please cite this article as: Hyndman, T.H., Marschang, R.E., Wellehan, J.F.X., Nicholls, P.K., Isolation and molecular identification of sunshine virus, a novel paramyxovirus found in australian snakes, Infection, Genetics and Evolution (2012), doi: http://dx.doi.org/10.1016/j.meegid.2012.04.022 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. -
Monitoring of Activity and Spread by Using Dead Bird Surveillance in Austria, 2003–2005 S
Monitoring of activity and spread by using dead bird surveillance in Austria, 2003–2005 S. Chvala, T. Bakonyi, C. Bukovsky, T. Meister, K. Brugger, F. Rubel, N. Nowotny, H. Weissenböck To cite this version: S. Chvala, T. Bakonyi, C. Bukovsky, T. Meister, K. Brugger, et al.. Monitoring of activity and spread by using dead bird surveillance in Austria, 2003–2005. Veterinary Microbiology, Elsevier, 2007, 122 (3-4), pp.237. 10.1016/j.vetmic.2007.01.029. hal-00532203 HAL Id: hal-00532203 https://hal.archives-ouvertes.fr/hal-00532203 Submitted on 4 Nov 2010 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Accepted Manuscript Title: Monitoring of Usutu Virus activity and spread by using dead bird surveillance in Austria, 2003–2005 Authors: S. Chvala, T. Bakonyi, C. Bukovsky, T. Meister, K. Brugger, F. Rubel, N. Nowotny, H. Weissenbock¨ PII: S0378-1135(07)00066-1 DOI: doi:10.1016/j.vetmic.2007.01.029 Reference: VETMIC 3583 To appear in: VETMIC Received date: 25-10-2006 Revised date: 26-1-2007 Accepted date: 31-1-2007 Please cite this article as: Chvala, S., Bakonyi, T., Bukovsky, C., Meister, T., Brugger, K., Rubel, F., Nowotny, N., Weissenbock,¨ H., Monitoring of Usutu Virus activity and spread by using dead bird surveillance in Austria, 2003–2005, Veterinary Microbiology (2007), doi:10.1016/j.vetmic.2007.01.029 This is a PDF file of an unedited manuscript that has been accepted for publication. -
Hutchinson, EC, & Yamauchi, Y
Hutchinson, E. C., & Yamauchi, Y. (2018). Understanding Influenza. In Influenza Virus: Methods and Protocols (pp. 1-21). (Methods in Molecular Biology; Vol. 1836). Humana Press. https://doi.org/10.1007/978-1-4939-8678-1_1 Peer reviewed version Link to published version (if available): 10.1007/978-1-4939-8678-1_1 Link to publication record in Explore Bristol Research PDF-document This is the author accepted manuscript (AAM). The final published version (version of record) is available online via Springer Nature at https://link.springer.com/protocol/10.1007%2F978-1-4939-8678-1_1. Please refer to any applicable terms of use of the publisher. University of Bristol - Explore Bristol Research General rights This document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/red/research-policy/pure/user-guides/ebr-terms/ Understanding Influenza Edward C. Hutchinson1* and Yohei Yamauchi2* 1MRC-University of Glasgow Centre for Virus Research; 2School of Cellular and Molecular Medicine, University of Bristol. *Corresponding authors: [email protected], [email protected] Running Head: Understanding Influenza Abstract Influenza, a serious illness of humans and domesticated animals, has been studied intensively for many years. It therefore provides an example of how much we can learn from detailed studies of an infectious disease, and of how even the most intensive scientific research leaves further questions to answer. This introduction is written for researchers who have become interested in one of these unanswered questions, but who may not have previously worked on influenza. -
University of Groningen Molecular Insights Into Viral Respiratory Infections Cong, Ying-Ying
University of Groningen Molecular insights into viral respiratory infections Cong, Ying-Ying IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2019 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Cong, Y-Y. (2019). Molecular insights into viral respiratory infections. University of Groningen. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 25-09-2021 CHAPTER I General Introduction Chapter I The structure of the respiratory tract facilitates gas exchange between the exterior environment and interior milieu of the host, while it is a susceptible target and feasible gateway for diverse pathogens. Pandemics of severe acute respiratory infections have been serious threats to global health, causing significant morbidity and mortality. In particular, influenza viruses and coronaviruses (CoV), including MERS-CoV and SARS-CoV, have caused numerous outbreaks of viral pneumonia worldwide with different impacts. -
Oncolytic Viruses for Canine Cancer Treatment
cancers Review Oncolytic Viruses for Canine Cancer Treatment Diana Sánchez 1, Gabriela Cesarman-Maus 2 , Alfredo Amador-Molina 1 and Marcela Lizano 1,* 1 Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City 14080, Mexico; [email protected] (D.S.); [email protected] (A.A.-M.) 2 Department of Hematology, Instituto Nacional de Cancerología, Mexico City 14080, Mexico; [email protected] * Correspondence: [email protected]; Tel.: +51-5628-0400 (ext. 31035) Received: 19 September 2018; Accepted: 23 October 2018; Published: 27 October 2018 Abstract: Oncolytic virotherapy has been investigated for several decades and is emerging as a plausible biological therapy with several ongoing clinical trials and two viruses are now approved for cancer treatment in humans. The direct cytotoxicity and immune-stimulatory effects make oncolytic viruses an interesting strategy for cancer treatment. In this review, we summarize the results of in vitro and in vivo published studies of oncolytic viruses in different phases of evaluation in dogs, using PubMed and Google scholar as search platforms, without time restrictions (to date). Natural and genetically modified oncolytic viruses were evaluated with some encouraging results. The most studied viruses to date are the reovirus, myxoma virus, and vaccinia, tested mostly in solid tumors such as osteosarcomas, mammary gland tumors, soft tissue sarcomas, and mastocytomas. Although the results are promising, there are issues that need addressing such as ensuring tumor specificity, developing optimal dosing, circumventing preexisting antibodies from previous exposure or the development of antibodies during treatment, and assuring a reasonable safety profile, all of which are required in order to make this approach a successful therapy in dogs.