Adult Onset Still's Disease Accompanied by Acute Respiratory Distress Syndrome: a Case Report
EXPERIMENTAL AND THERAPEUTIC MEDICINE 12: 1817-1821, 2015 Adult onset Still's disease accompanied by acute respiratory distress syndrome: A case report XIAO-TU XI1, MAO‑JIE WANG2, RUN‑YUE HUANG2 and BANG‑HAN DING1 1Emergency Department; 2Rheumatology Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong 510006, P.R. China Received July 17, 2015; Accepted May 20, 2016 DOI: 10.3892/etm.2016.3512 Abstract. Adult onset Still's disease (AOSD) is a systemic vascular permeability and a loss of aerated lung tissue (8). inflammatory disorder characterized by rash, leukocytosis, ARDS occurs in 7.2‑38.9/100,000 individuals (9,10), and has fever and arthralgia/arthritis. The most common pulmo- a mortality rate of ~40% (11). Patient mortality varies based nary manifestations associated with AOSD are pulmonary on numerous factors, including age, etiology of the lung injury infiltrates and pleural effusion. The present study describes and non‑pulmonary organ dysfunction. The most common a 40‑year‑old male with AOSD who developed fever, sore risk factors for ARDS are pneumonia, sepsis, aspiration and throat and shortness of breath. Difficulty breathing promptly trauma (11). Multiple predisposing risk factors, in addition to developed, and the patient was diagnosed with acute respira- some secondary factors such as alcohol abuse and obesity, also tory distress syndrome (ARDS). The patient did not respond increase the risk (4). In addition to patient support provided by to antibiotics, including imipenem, vancomycin, fluconazole, improving oxygen delivery to the tissues and preventing multi- moxifloxacin, penicillin, doxycycline and meropenem, but was organ system failure, early recognition and correction of the sensitive to glucocorticoid treatment, including methylpred- underlying cause is important in ARDS treatment.
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