www.biovision.com preclinical lead identification assayspotency and for developmentthe novelof therapeutics. from the therapeutic antibody to achieve similar and efficacy. safety These antibodies becan used as controls for regions variable with technology recombinant using manufactured are antibodies monoclonal Our needs. research hematological malignancies. BioVision is pleased to offer research grade biosimilars in human IgG format for your monoclonal antibodies have received FDA approval for the treatment of solid of a variety tumors and (CDC),cytotoxicity antibody-dependent cellular (ADCC) cytotoxicity or regulation of Tcell Several function. through receptor of apoptosis; induction or blockade cell immune-mediated killing by complement-dependent therapy. Several mechanisms of tumor cell killing by antibodies (mAbs) can summarized be as: action direct Human based monoclonal IgG antibodies (mAbs) are the fastest-growing of therapeutics category for cancer Toll Free: 800-891-9699 (US Only) Toll Free: 800-891-9699 F:T: 408-493-1801 408-493-1800 CA 95035 Blvd, Milpitas, 155 Milpitas S. Anti-EGFR (Matuzumab),Anti-EGFR IgG1 Human Anti-EGFR (Cetuximab), Chimeric (Campath-1H),Anti-CD52 IgG1 Human (), IgG1 Human Anti-CD40L (), IgG4 Human Anti-CD4 Anti-CD33 (Gemtuzumab), IgG4 Human (Epratuzumab),Anti-CD22 IgG1 Human Anti-CD20 (Rituximab), Chimeric Anti-CD11a (), Human IgG1 (Arcitumomab), IgG1 Human Anti-Carcinoembryonic 1IntegrinAnti-alpha (Volociximab), 5beta Human IgG4 Biosimilar Monoclonal Antibodies Monoclonal Biosimilar Antibody Name Name Antibody Cat. No. Cat. A1090 A1094 A1096 A1089 A1049 A1445 A1443 A1092 A1047 A1091 A1105 Trade Name LymphoCide Mabthera CEA-Scan Campath Mylotarg Raptiva Antova Erbitux - - - Isotype IgG4 IgG4 IgG4 IgG1 IgG1 IgG1 IgG1 IgG1 IgG1 IgG1 IgG1 200 µg 200 µg 200 µg 200 µg 200 µg 200 µg 200 µg 200 µg 200 µg 200 100 µg 100 µg 100 Size Antibody Name Cat. No. Trade Name Isotype Size Anti-EGFR (Panitumumab), Humanized A1050 Vectibix IgG1 100 µg Anti-HER2 (Trastuzumab), Humanized A1046 Herceptin IgG1 100 µg Anti-IL-2R alpha (CD25) (), Human IgG1 A1098 Simulect IgG1 200 µg Anti-IL-2R alpha (), Human IgG1 A1099 Zenapax IgG1 200 µg Anti-IL-6 receptor (), Human IgG1 A1447 Actemra IgG1 200 µg Anti-Integrin alpha 4 (), Human IgG4 A1444 Tysabri IgG4 200 µg Anti-OX40L (), Human IgG1 A1088 Xolair IgG1 200 µg Anti-PD-1 (), Humanized A1307 Opdivo IgG4 100 µg Anti-PD-1 (), Humanized A1306 Keytruda IgG4 100 µg Anti-PD-L1 (), Humanized A1305 Tecentriq IgG1 100 µg Anti-RSV (Felvizumab), Human IgG1 A1446 - IgG1 200 µg Anti-TNF alpha (Humicade), Human IgG4 A1093 Humicade IgG4 200 µg Anti-TNF alpha (), Human IgG1 A1097 Remicade IgG1 200 µg Anti-TNF-α (), Humanized A1048 Humira IgG1 100 µg Anti-VEGF (Bevacizumab), Humanized A1045 Avastin IgG1 100 µg Anti-TAG 72 (Satumomab), Mouse IgG1, kappa A2017 OncoScint® IgG1 200 µg Anti-CD80 (), Human IgG1, lambda A2011 IgG1 200 µg Alemtuzumab, Mab- Anti-CD4 (Campath-9H), Rabbit IgG, kappa A2012 IgG 200 µg campath, Lemtrada Anti-CD3 epsilon (Muromonab), Mouse IgG2a, kappa A2008 Orthoclone OKT3 IgG2a 200 µg Biomab, Theracim, Anti-EGFR domain III (Nimotuzumab), Human IgG1, kappa A2004 Theraloc, Cimaher, IgG1 200 µg CIMAher, Taixinsheng Anti-CCR4 (), Human IgG1, kappa A2005 Poteligeo IgG1 200 µg

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