Oral and Maxillofacial Medicine
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59. Lateral Facial Clefts
59 LATERAL FACIAL CLEFTS LI OR TRANSVERSE CLEFTS ARE CONSIDERED THE RESULT OF FAILURE OF MESODERM MIGRATION OR MERGING TO OBLITERATE MANDIBULAR THE EMBRYONIC GROOVES BETWEEN THE MAXILLARY AND PROMINENCES TRANSVERSE CLEFTS AS THESE CLEFTS ARE RARE AND ALMOST EVERYBODY HAVING ONE HAS AND REPORTED IT IT IS POSSIBLE TO REVIEW MOST OF THE REPORTED CASES 769 DESCRIBED THE AFTER WHEN NOTE TREATMENT SPECIFIC CASE RECORDINGS IN WHAT MAY SEEM HELTERSKELTER ARRANGEMENT GENERALIZATIONS MAY BE OF VALUE IN 1891 ROSE NOTED FOR LONG THE VERY EXISTENCE OF THIS MACROSROMATOUS DEFORMITY WAS DOUBTED BUT CASES HAVE BEEN RECOGNIZED MORE OR LESS SINCE 1715 WHEN MURALT PICTURED IT FOR THE FIRST TIME ONE OF THE FIRST CASES REPORTED WAS BY VROLIK WHOIN HIS 1849 CLEFTS WORK GAVE SEVERAL ILLUSTRATIONS OF COMMISSURAL AS WELL AS OTHER DEFORMITIES OF THE FACE OTHER CASES WERE REPORTED BY REISSMANN IN 1869 AND MORGAN IN 1882 MACROSTOMIA OR COMMISSURAL HARELIP ACCORDING TO ROSE IS DIAMETER OF WHICH EVIDENCED BY AN INCREASED THE MOUTH MAY VARY IN FROM SLIGHT INCREASE TO CONSIDERABLE DISTANCE CASE RE PORTED BY RYND IN 1862 THE MOUTH OPENING EXTENDED AS FAR AS THE THE LEFT FIRST MOLAR ON THE RIGHT SIDE AND TO THE LAST MOLAR ON IN 1887 SUTTON PUBLISHED THE DRAWING OF CHILD WITH VERY LARGE RED CICATRIX THIS CLEFT THE ANGLES OF WHICH GRADUALLY PASSED INTO SCAR ENDED IN GAPING WOUND OVER THE TEMPORAL REGION EXTEND ING TO THE DURA MATER ROSE ALSO POINTED OUT MACROSROMA IS NOR ONLY ATTENDED BY GREAT DISFIGUREMENT HUT IS ALSO TROU BLESOME FROM THE IMPOSSIBILITY OF THE CHILD RETAINING -
Oral Lesions in Leprosy
Study Oral lesions in leprosy Ana Paula Fucci da Costa, José Augusto da Costa Nery, Maria Leide Wan-del-Rey de Oliveira, Tullia Cuzzi,* Marcia Ramos-e-Silva Departments of Dermatology & *Pathology, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Brazil. Address for correspondence: Marcia Ramos-e-Silva, Rua Sorocaba 464/205, 22271-110, Rio de Janeiro, Brazil. E-mail: [email protected] ABSTRACT Background: Leprotic oral lesions are more common in the lepromatous form of leprosy, indicate a late manifestation, and have a great epidemiological importance as a source of infection. Methods: Patients with leprosy were examined searching for oral lesions. Biopsies of the left buccal mucosa in all patients, and of oral lesions, were performed and were stained with H&E and Wade. Results: Oral lesions were found in 26 patients, 11 lepromatous leprosy, 14 borderline leprosy, and one tuberculoid leprosy. Clinically 5 patients had enanthem of the anterior pillars, 3 of the uvula and 3 of the palate. Two had palatal infiltration. Viable bacilli were found in two lepromatous patients. Biopsies of the buccal mucosa showed no change or a nonspecific inflammatory infiltrate. Oral clinical alterations were present in 69% of the patients; of these 50% showed histopathological features in an area without any lesion. Discussion: Our clinical and histopathological findings corroborate earlier reports that there is a reduced incidence of oral changes, which is probably due to early treatment. The maintenance of oral infection in this area can also lead to and maintain lepra reactions, while they may also act as possible infection sources. -
Ackerman's Tumour of Buccal Mucosa in a Leprosy Patient
Lepr Rev (2013) 84, 151–157 CASE REPORT Ackerman’s tumour of buccal mucosa in a leprosy patient MANU DHILLON*, RAVIPRAKASH S. MOHAN**, SRINIVASA M. RAJU***, BHUVANA KRISHNAMOORTHY* & MANISHA LAKHANPAL* *Department of Oral Medicine and Radiology, ITS Centre for Dental Studies and Research, Ghaziabad, India **Department of Oral Medicine and Radiology, Kothiwal Dental College and Research Centre, Moradabad, India ***Department of Oral Medicine and Radiology, Saraswati Dental College, Lucknow, India Accepted for publication 23 April 2013 Summary Leprosy (Hansen’s disease) is a chronic granulomatous disease caused by Mycobacterium leprae (Hansen’s bacillus). Oral manifestations occur in 20–60% of cases, usually in lepromatous leprosy, and are well documented. They may involve both the oral hard and soft tissues. Incidence of verrucous carcinoma/Ackerman’s tumour developing in anogenital region and plantar surfaces of feet in lepromatous leprosy has been sufficiently documented in the literature. However, association of oral verrucous carcinoma with lepromatous leprosy has not been established. We report for the first time a case of verrucous carcinoma of the buccal mucosa occurring in a leprotic patient, with brief review of literature on orofacial manifestations of leprosy. Introduction Leprosy (Hansen’s disease) is a chronic, contagious granulomatous disease caused by Mycobacterium leprae (Hansen’s bacillus). The disease presents polar clinical forms (the ‘multibacillary’ or lepromatous leprosy, and ‘paucibacillary’ or tuberculoid leprosy), -
Otocephaly: Agnathia-Microstomia-Synotia Syndrome Tanya Kitova1, Borislav D Kitov2
CASE REPORT Otocephaly: Agnathia-Microstomia-Synotia Syndrome Tanya Kitova1, Borislav D Kitov2 ABSTRACT The aim of the study is to present otocephaly, which is a rare congenital lethal malformation. Until this moment, only a little bit more than 100 cases worldwide were reported, and only 22 cases of prediagnosed otocephaly. Background: Otocephaly or agnathia-microstomia-synotia syndrome (SAMS) is characterized by agenesis of mandible (agnathia), disposition or fusion of the auricle (synotia), microstomia, and complete or partial lack of language (aglossia), which often ends up lethal. Case description: A 499.7 g male fetus was obtained after a therapeutic abortion during the 23rd gestational week at the Center for Maternity and Neonatology, Embryo-fetopathology Clinic, Tunis, Tunisia. The mother is an 18-year-old with close relative marriage with first-degree incest, primigravida. Examination of the fetus revealed microcephaly with craniosynostosis, hypertelorism, closed eyelid exophthalmos, one nostril, point microstomia, mandibular agenesis, bilateral, and auditory cysts of neck. The ears are located at the level of the neck. A study of the brain and the base of the skull revealed holoprosencephaly and sphenoid bone agenesis. There are no internal organ abnormalities. Conclusion: In cases where, at the end of the second trimester of pregnancy, polyhydramnios is detected, inability to visualize the mandible, and malposition of ears, otocephaly should be suspected. In these cases, the decision to interrupt pregnancy should be taken by a multidisciplinary team, after an magnetic resonance imaging, which is much better in visualizing location of the ears and other facial malformations and the presence of other associated anomalies. -
Case Report Treatment of Geographic Tongue
Scholars Journal of Dental Sciences (SJDS) ISSN 2394-496X (Online) Sch. J. Dent. Sci., 2015; 2(7):409-413 ISSN 2394-4951 (Print) ©Scholars Academic and Scientific Publisher (An International Publisher for Academic and Scientific Resources) www.saspublisher.com Case Report Treatment of Geographic Tongue Superimposing Fissured Tongue: A literature review with case report Jalaleddin H Hamissi1, Mahsa EsFehani2, Zahra Hamissi3 1Associate Professor in periodontics and Dental Caries Prevention Research Center, Qazvin University Medical Sciences, Qazvin, Iran. 2Assistant Professor, Department of Oral Medicine & Diagnosis, college dentistry, Qazvin University Medical Sciences, Qazvin, Iran. 3Dental Student, College of Dentistry, Shahied Behesti University of Medical Sciences, Teheran, Iran *Corresponding author Dr Jalaleddin H Hamissi Email: [email protected] ; [email protected] Abstract: Tongue is a most sensitive part of the oral cavity. It is responsible for many functions in the mouth like swallowing, speech, mastication, speaking and breathing. Geographic tongue (Benign migratory glossitis, erythema migrans) is an asymptomatic inflammatory disorder of tongue with controversial etiology. This disease is characterized by erythematous areas showing raised greyish or white circinate lines or bands with irregular pattern on the dorsal surface of the tongue and depapillation. The objective in presenting the case report and literature review is to discuss the clinical presentation, associated causative factors and management strategies of geographic tongue. Keywords: Asymptomatic; Characteristics; Fissured tongue; Geographic tongue; Migratory INTRODUCTION in approximately three percent (3%) majority of female Geographic tongue is an asymptomatic population [9]. On other aspects of oral mucosa, such as inflammatory condition of the dorsum of tongue on commissure of lip, floor of mouth, cheek etc., which occasionally extending towards the lateral borders. -
Prevalence and Incidence of Rare Diseases: Bibliographic Data
Number 1 | January 2019 Prevalence and incidence of rare diseases: Bibliographic data Prevalence, incidence or number of published cases listed by diseases (in alphabetical order) www.orpha.net www.orphadata.org If a range of national data is available, the average is Methodology calculated to estimate the worldwide or European prevalence or incidence. When a range of data sources is available, the most Orphanet carries out a systematic survey of literature in recent data source that meets a certain number of quality order to estimate the prevalence and incidence of rare criteria is favoured (registries, meta-analyses, diseases. This study aims to collect new data regarding population-based studies, large cohorts studies). point prevalence, birth prevalence and incidence, and to update already published data according to new For congenital diseases, the prevalence is estimated, so scientific studies or other available data. that: Prevalence = birth prevalence x (patient life This data is presented in the following reports published expectancy/general population life expectancy). biannually: When only incidence data is documented, the prevalence is estimated when possible, so that : • Prevalence, incidence or number of published cases listed by diseases (in alphabetical order); Prevalence = incidence x disease mean duration. • Diseases listed by decreasing prevalence, incidence When neither prevalence nor incidence data is available, or number of published cases; which is the case for very rare diseases, the number of cases or families documented in the medical literature is Data collection provided. A number of different sources are used : Limitations of the study • Registries (RARECARE, EUROCAT, etc) ; The prevalence and incidence data presented in this report are only estimations and cannot be considered to • National/international health institutes and agencies be absolutely correct. -
Prevalence of Oral Mucosal Lesions in Geriatric Patients in Universitas Airlangga Dental Hospital
ORIGINAL ARTICLE Prevalence of Oral Mucosal Lesions in Geriatric Patients in Universitas Airlangga Dental Hospital Fatma Yasmin Mahdani, Desiana Radithia, Adiastuti Endah Parmadiati and Diah Savitri Ernawati Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia ABSTRACT Background. Population aged 60 years old and above are growing in number; a fact that will have an impact on general and oral health in the future. Oral health is often overlooked in the management of geriatric patients but it is vital to have a knowledged-based practice in order to increase the quality of life of elderly patients. Objective. The purpose of this study is to determine the number and types of oral mucosal lesions in geriatric patients who come to the Universitas Airlangga Dental Hospital. Methods. This is an observational descriptive study with cross-sectional design. Intraoral soft tissue examination was performed on geriatric patients coming to the hospital between March and December 2018. Results. One hundred twenty-four (124) new geriatric patients came to the hospital. A total of 152 oral lesions from 63 geriatric patients (50.81%) were identified. Overall, coated tongue (55.56%) was the most frequently detected lesion, followed by linea alba buccalis (31.74%) and lingual varicosities (26.98%). Conclusion. Coated tongue or white tongue is the most frequently detected oral mucosal lesion, often caused by poor oral hygiene. The dentist should be able to recognize and differentiate them from the worrisome lesions and decide on the appropriate treatment in geriatric patients. Key Words: oral mucosa, mouth diseases, geriatric dentistry INtroductioN According to the Government Regulation of the Republic of Indonesia Number 43 of 2004, an elderly person is someone who has reached the age of 60 years and over. -
Abstracts from the 51St European Society of Human Genetics Conference: Electronic Posters
European Journal of Human Genetics (2019) 27:870–1041 https://doi.org/10.1038/s41431-019-0408-3 MEETING ABSTRACTS Abstracts from the 51st European Society of Human Genetics Conference: Electronic Posters © European Society of Human Genetics 2019 June 16–19, 2018, Fiera Milano Congressi, Milan Italy Sponsorship: Publication of this supplement was sponsored by the European Society of Human Genetics. All content was reviewed and approved by the ESHG Scientific Programme Committee, which held full responsibility for the abstract selections. Disclosure Information: In order to help readers form their own judgments of potential bias in published abstracts, authors are asked to declare any competing financial interests. Contributions of up to EUR 10 000.- (Ten thousand Euros, or equivalent value in kind) per year per company are considered "Modest". Contributions above EUR 10 000.- per year are considered "Significant". 1234567890();,: 1234567890();,: E-P01 Reproductive Genetics/Prenatal Genetics then compared this data to de novo cases where research based PO studies were completed (N=57) in NY. E-P01.01 Results: MFSIQ (66.4) for familial deletions was Parent of origin in familial 22q11.2 deletions impacts full statistically lower (p = .01) than for de novo deletions scale intelligence quotient scores (N=399, MFSIQ=76.2). MFSIQ for children with mater- nally inherited deletions (63.7) was statistically lower D. E. McGinn1,2, M. Unolt3,4, T. B. Crowley1, B. S. Emanuel1,5, (p = .03) than for paternally inherited deletions (72.0). As E. H. Zackai1,5, E. Moss1, B. Morrow6, B. Nowakowska7,J. compared with the NY cohort where the MFSIQ for Vermeesch8, A. -
ORAL PATHOLOGY Questionnaire – 2018/2019 Ac. Year
ORAL PATHOLOGY Questionnaire – 2018/2019 ac. year A. Specific part (oral examination): 1. Normal anatomy. 2. Variants of normal anatomy and common benign conditions. 3. Medical history. 4. Clinical examination. 5. Diagnostic tests and studies – radigraphic studies, intraoral photography. 6. Diagnostic tests and studies – blood tests, biopsy and cytology. 7. Microbiological tests. 8. Orofacial pain conditions. 9. Burning mouth syndrome. 10. Bacterial infections in the mouth. 11. Viral and fungal infections in the mouth. 12. Respiratory diseases. Management. 13. Cardiovascular diseases. Management. 14. Diseases of the esophagus, GERD, Barrett's syndrome, H. pylori infections. Dentist’s management. 15. Liver diseases. Chronic hepatitis. Dentist’s management. 16. Bowel diseases - Ulcerative colitis and Crohn's disease. Dentist’s management. 17. Corticosteroid therapy. 18. Pregnancy. Dentist’s management. 19. Emergencies in dental practice. 20. Hypothyroidism. Hyperthyroidism. Diabetes mellitus. Dentist’s management. 21. Cushing's syndrome. Addison's disease. Dentist’s management. 22. Anemia. Agranulocytosis. Dentist’s management. 23. Leukemias. Dentist’s management. 24. Lymphomas. Dentist’s management. 25. Bleeding diathesis. Dentist’s management. 26. Renal diseases and dentistry 27. Sjogren's syndrome 28. Cerebrovascular disease-multiple sclerosis, alzheimer’s disease, seizure disorders, parkinson’s disease, myasthenia gravis 29. Nutritional deficiencies. 30. Intellectual and physical disability. B. General part (written examination): 1. Cheilitis simplex. Angular and granulomatous cheilitis. Melkersson– Rosenthal syndrome. 2. Actinic, allergic, exfoliative and precancerous cheilitis. 3. Glandular cheilitis. Angioneurotic oedema. Lymphoedema due to radiotherapy. 4. Sarcoidosis. Cystic fibrosis. Median lip fissure. 5. Freckles. Peutz-Jeghers syndrome. 6. Microglossia. Macroglossia. 7. Crenated tongue. Fissured tongue. 8. Geographic tongue. Median rhomboid glossitis. 9. -
MW Efficacy In
Journal of International Dental and Medical Research ISSN 1309-100X Oral Lesions in Patients with Tuberculosis http://www.jidmr.com Reiska Kumala Bakti and et al Oral Lesions in Patients with Tuberculosis: A Cross-Sectional Study Reiska Kumala Bakti*1, Priyo Hadi1, Bagus Soebadi1, Diah Savitri Ernawati1, Ni Made Mertaniasih2 1. Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia 2. Department of Clinical Microbiology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Abstract Tuberculosis (TB) is one of the world’s deadliest infectious diseases and predominantly affects the lungs. TB could also occur in other sites of the body, such as the oral cavity. The oral manifestation incidence of TB is approximately 0.05%–5%. Despite being a rare occurrence, oral TB remains a challenging issue because of its nonspecific clinical presentation. This study aims to assess and determine the oral lesions of patients with TB. In this cross-sectional study, we examined the oral cavity of patients with TB to assess the appearance of oral lesions in each patient. In 30 patients with pulmonary TB, we identified 29 oral lesions on the tongue. One patient was suspected with oral tubercular lesion, and four patients had Candida infection–related lesions. Most lesions were classified as normal variant lesions of the oral mucosa, with the coated tongue exhibiting the highest incidence. The tongue is often affected by patients’ systemic condition. Conclusion: Results suggest that although most patients with TB have oral lesions, the oral TB incidence remains rare. Considering that some lesions might be asymptomatic, dentists could play a vital role in the early diagnosis of lesions for further management. -
Seminarium: Podstawy Dysmorfologii
The seminar: DYSMORPHOLOGY Tutor: Marzena Wisniewska, M.D., Ph.D. Dysmorphology – is the recognition and study of birth defects and syndromes. The term “dysmorphic” is used to describe children whose physical features are not usually found in a child of the same age or ethnic background. Some features are abnormal in all circumstances, e.g. premature fusion of the cranial sutures, whereas other features may be a non-significant familial trait, e.g. 2/3 toe syndactyly. Dysmorphology examination checklist: Growth parameters – according to centile charts: height, weight, upper limbs, lower limbs short stature gigantism – proportionate or disproportionate Anomalies: Macrosomia – too big stature Microsomia – too small stature Hemihypertrophy – asymmetric half of the body or a single limb Cranium OFC – occipital – frontal circumference symmetry cranial sutures fontanelle Anomalies: Microcephaly – abnormally small head, OFC < 3 SD Macrocephaly – abnormally large head Hydrocephalus – impared circulation and absorption of cerebrospinal fluid Craniostenosis – premature fusion of all sutures Craniosynostosis – premature fusion of one suture – change of skull shape: Scaphocephaly (dolicocephaly) – increased lenght compared to width of skull (saggital synostosis) Brachycephaly – flattening of the occiput with increased width compared to lenght of the skull (bilateral coronal synostosis) Plagiocephaly – asymmetry of the head shape (unilateral coronal or lambdoid synostosis) Trigonocephaly – the forehead assumes a triangular shape (metopic synostosis) -
Description Concept ID Synonyms Definition
Description Concept ID Synonyms Definition Category ABNORMALITIES OF TEETH 426390 Subcategory Cementum Defect 399115 Cementum aplasia 346218 Absence or paucity of cellular cementum (seen in hypophosphatasia) Cementum hypoplasia 180000 Hypocementosis Disturbance in structure of cementum, often seen in Juvenile periodontitis Florid cemento-osseous dysplasia 958771 Familial multiple cementoma; Florid osseous dysplasia Diffuse, multifocal cementosseous dysplasia Hypercementosis (Cementation 901056 Cementation hyperplasia; Cementosis; Cementum An idiopathic, non-neoplastic condition characterized by the excessive hyperplasia) hyperplasia buildup of normal cementum (calcified tissue) on the roots of one or more teeth Hypophosphatasia 976620 Hypophosphatasia mild; Phosphoethanol-aminuria Cementum defect; Autosomal recessive hereditary disease characterized by deficiency of alkaline phosphatase Odontohypophosphatasia 976622 Hypophosphatasia in which dental findings are the predominant manifestations of the disease Pulp sclerosis 179199 Dentin sclerosis Dentinal reaction to aging OR mild irritation Subcategory Dentin Defect 515523 Dentinogenesis imperfecta (Shell Teeth) 856459 Dentin, Hereditary Opalescent; Shell Teeth Dentin Defect; Autosomal dominant genetic disorder of tooth development Dentinogenesis Imperfecta - Shield I 977473 Dentin, Hereditary Opalescent; Shell Teeth Dentin Defect; Autosomal dominant genetic disorder of tooth development Dentinogenesis Imperfecta - Shield II 976722 Dentin, Hereditary Opalescent; Shell Teeth Dentin Defect;