Ibogaine Scientific Literature Overview composed by The International Center for Ethnobotanical Education, Research & Service Advisors: José Carlos Bouso & Kenneth R. Alper, MD 2012 Tabel of Content 1.0 Overview 1.1 Ibogaine: A Review - 2001 2.0 Relevant Preclinical Literature 2.1 Dzolic et al 1988 2.2 Cappendijk et al 1993 2.3 Glick et al 1994 2.4 Glick et al 2002 2.5 He et al 2005 2.6 He & Ron et al 2006 2.7 Carnicella et al 2010 2.8 Paskulin et al 2010 2.9 Paskulin et al 2012 3.0 Toxicology & Psychological risks 3.1 Mash et al 1998 3.2 Kubilienè et al 2008 3.3 NEJM 2009 3.4 Tachyarrhythmias 2011 3.5 Psychosis in Schizophrenia 2011 3.6 Pornography Addiction 2011 3.7 Alper et al 2012 4.0 Evidence of Efficacy in Humans 4.1 Alper et al 1999 4.2 Mash et al 2001 4.3 Alper et al 2008 4.4 Maciulaitis et al 2008 5.0 Regulation 5.1 Medsafe 2009 5.2 Donnelly 2011 5.3 JPHC 2011 International Center for Ethnobotanical Education, Research & Service Nieuwe Zandstraat 4 4661AP Halsteren Netherlands c/Sants 168 3.1. 08014 Barcelona Spain tel.: +34931857912 email:
[email protected] www.iceers.org Advisors: José Carlos Bouso
[email protected] Kenneth R. Alper, MD ICEERS 2012
[email protected] 3 Overview composed by The International Center for Ethnobotanical Education, Research & Service Advisors: José Carlos Bouso & Kenneth R. Alper, MD ——Chapter 1—— IBOGAINE: A REVIEW Kenneth R. Alper Departments of Psychiatry and Neurology New York University School of Medicine New York, NY 10016 I.