Rekha R.Deokar et al. / Journal of Pharmacy Research 2012,5(2),1001-1003 Research Article Available online through ISSN: 0974-6943 www.jpronline.info Survey of Ethno medicinal Plants with Antidiabetic Potential from Chandoli, Dist. , (M.S.) .

Rekha R. Deokar1, Shubhangi R. Kamble2, Satish R. Mane3 and Sarjerao R. Patil4 1 &2Assistant Professor, D. A. B .N. College, Chikhali, Tal.- Shirala, Dist.- Sangli, Maharastra, India 3Director of Phy. Education , D. A. B .N. College, Chikhali, Tal.- Shirala, Dist.- Sangli, Maharastra, India 4Pricipal, D. A. B .N. College, Chikhali, Tal.- Shirala, Dist.- Sangli.(M.S.) India Maharastra, India Received on:10-11-2011; Revised on: 15-12-2011; Accepted on:12-01-2012

ABSTRACT Chandoli, a hilly region is rich in ethno medicinal plants. In the present paper 42 plant species belonging to 26 families used in folk medicines for treatment of diabetes. Due to poor condition of modern health care facilities and poverty indigenous peoples of the district fully or partially depends on local medicinal plants. An attempt has been made to document traditional knowledge of local people of Chandoli on treatment of diabetes.

Key words: Ethno Medicinal plants, Antidiabetic potential , Chandoli. INTRODUCTION Diabetes mellitus is a clinical syndrome characterized by inappropriate hyperglycemia caused by insufficient insulin production or by a resistance to the action of insulin at the cellular level. It is a major health problem caused by endocrine disorder. About 200 million persons affected by diabe- tes worldwide and is projected to become one of the world’s main disablers and killer within the next 25 years. The management of Diabetes mellitus is global problem until now and successful treatment is not yet discovered. There are many oral hypoglycemic agents developed for patients but no one has ever been reported totally from Diabetes. Hence there is lot of scope for alternative therapy herbal formulation or indigenous plants add on therapy (Satyanarayana et al. 2006; Debra, 1991).

The herbal treatment has very deep roots in Indian culture. In rural areas, people are depending on herbal drug system for primary health care. The present paper deals with primary information of the traditional medicine referring to treat diabetes from chandoli Tal. Shirala, Dist. Sangli (MS) India. MATERIAL AND METHOD

Study area Chandoli is Indian National Park established in May 2004 (Loksatta, 2004). Early a Wildlife Sanctuary declared in 1985 (Times of India , 2004). It is located near the Chandoli dam, between longitude 730 40’ E and 730 53’ E and latitude 170 03’ N and 170 20’ N near Sangli in Western . It is located at the junction of Sangli, , Satara and Ratnagari Districts. It is one of the hot spot for biodiversity from Western Ghat.( Gazetteer of India,1969) The present study is based on the intensive field survey in interior villages adjoining forest area to collect ethno botanical core. First hand information was gathered through interactions with rural people including members of forest protection committee, elderly people, traditional medical practitio- ners and local vaidues. Herbal plants referred by these people were authen- tically identified with the help of The Flora of The Presidency of Bombay, Botanical Survey of India (Theodore Cooke,1967). *Corresponding author. Rekha R.Deokar The collected information was documented for their antidibetic properties. Assistant Professor, The collected information is arranged in the alphabetic order of plants with D. A. B .N. College, Chikhali, botanical name, along with local or common name, vernacular name, parts Tal.- Shirala, Dist.- Sangli used, local use, active principle and use for each plants . To ascertain the Maharastra, India uses of these medicinal plants the earlier published scientific literature sources referred to are: Anonymous (2003),Anonymous (1962), Sharma et al. (1985- 86), Jain (1991), Kirtikar and Basu (1975,1991), Ambasta et al. (1992) and

Journal of Pharmacy Research Vol.5 Issue 2.February 2012 1001-1003 Rekha R.Deokar et al. / Journal of Pharmacy Research 2012,5(2),1001-1003 Chopra et al.(1996). Agarwal et al.(2005), Nadkarni (2002),Kapase on biochemical and pharmaceutical aspects. About 42 plant species were H.(2003),Karve (2005), Panigrahi. and Panigrahi (2000). used for treatment of diabetes.

RESULT AND DISCUSSION The study area is rich in medicinal plants resources. And attempt was made Although our ancient sages through hit and trial method developed herbal to collect information on the traditional medicinal knowledge present with medicines, the reported use of plant species do not certify efficacy (Tarafdar, the local peoples. However more in depth information may be explored 1989). The present preliminary report on ethno medicinal uses of some from tribes. This type of study will give new impetus to the traditional plant species need to pharmacologically screened, chemically analyzed and system of healthcare. In view of the importance of traditional medicine tested for bioactive activities (Chandler et al, 1979; Fairbairn, 1980) which provides health services to 75-80% of the world population in- creased demand of herbal drugs by pharmaceutical and depleting natural The paper present a brief account of the uses of various ethno medicinal plant resources. It is high time to document the medicinal utility of less plant parts like bark, flowers, rhizomes, roots, leaves, seeds, gum and known plants available in remote areas of country (Zaidi and Crow, 2005). whole plant against diabetes. It highlights the need for further investigation Table1: List of ethno medicinal plants with their common name, local name, part used, Active Constituent and local uses.

Sr. No Botanical name and family Common name Local name Part used Active constituent Local use

1 Abroma augusta, Linn (Sterculiaceae) Devil’s cotton Ulat-Kambal Root, Stem, Leaves Alkaloids, Fixed oil Uterine Tonic 2. Aconitum carmichaeii, ‘Arendsii’ Monkshood Bach nag Tuberous roots Hampnapelline, Napelline Decreasing quantity of urine (Ranunculaceae) and sugar 3 Aegle marmelos, Corr. (Rutaceae) Bel Tree Bel Tree Leaves, Fruit Rutacine,agelamine,marmine,marmelosin. Anti oxidant, anti acidic, Kidney Purifier 4 Allium sativum, L.(Liliaceae) Garlic Lasun Bulb Allicin,Germanium Magnesium High blood pressure. Selenium Vitamin A 5 Allium cepa, L.(Liliaceae) Onion Kanda Bulb Allyl propyl disulphide catarrh of the eyes, nose, and larynx ; neuralgic pains 6 Alove barbadensis, Miller.(Liliaceae) Aloe Korphad Leaf Pulp Cinnamoyl-C-Glycoside Chromone, Blood purifier, anti acidic, Anthraquimone anti inflammatory 7 Boerhavia diffusa , Linn.(Nyctaginaceae) Vasu Punarnava Whole Plant Pnarnavine Diuretic,jaundice,Anaemia 8 Butea monosperma, Lamk.(Fabaceae) Jungle Flame tree Palas Stem, Bark, Leave Bioflavonoid, theols, meso-inositol Diuretic, Diabetes, Astringent 9 Capsicum annum , Prain. (Solanaceae) Chilly Mirchi fruit Ascorbic acid Antioxidant 10 Cassia auriculata, L.(Caesalpiniaceae) Cassia Tarvad Root, Bark, leaves, Di (2-Ethyl) hexylpthalate Chylous urine, Jaundis flowers, Seeds 11 Cassia fistula, L.(Caesalpiniaceae) Golden shower Bahava Root, Bark, leaves, pod Glutimic acid, Glycoside Fever, Diseases of heart, Laxative flowers, Seeds 12 Cassia sophora, L.(Caesalpiniaceae) Senna Ran-Takala Juice of rut Emodin, Chrysophanic acid Diminishes urine 14 Curcuma longa , L. (Zingiberaceae) Turmeric Halad Tubers and Rhizomes Curcuminoids,Desmethoxy curcumin Blood purifier, anti acidic, anti inflammatory 15 Dioscorea japonica, L. (Dioscoraceae) Bitter yam Bitter yam Rhizomes and Root Glycan A B C D E I Antidibetic,Sugar destroying agent 16 Eriodendron anfractuosum, DC White silk cotton Pandhari savar Gum, Unripe Fruits, Triglycerides of Oleic Acid, Diabetes, Diarrohea and Dysentry (Bombaceae) tree Linoleic Acid, Gallic Acid Seeds,Flower, Root 17 Eugenia jambolana, Lamk. (Myrtaceae) Black Berry Jambhul Fruit, Leaves, Dried Ellagic Acid, Albumen Diabetes, Astringent, diuretic Seeds, Bark 18 Euphorbia prostrate, L. (Euphorbiaceae) prostrate sandm Dudhani Leaves Apigenin, Leuteolin, Quorcetin treatment of bleeding 19 Ficus benghalensis, L. (Moraceae) Baniyan tree Vad Stem, Bark, Leave, Bioflavonoid, theols Chylous urine, Astringent, 20 Ficus glomerata, Roxb. (Moraceae) Fig tree Umbar Stem, Bark, Leave, Fruit Not clearly known Diabetes, Astringent, diuretic 21 Fumaria parviflora ,Lan. (Fumariaceae) Fineleaf fumitory Fumitory Fruit, Leaves, Seeds, Fumarine,fumaric acid Antihypoglycemic 22 Gymnema sylvestre, R. Br. (Asclepidaceae) Kavali Bedakicha pala Leaves Gymnemosides 1-7,Gymnemic acid Antidibetic,Sugar destroying agent 23 Galega officinalis, L.(Fabaceae) professor-weed, Goat’s Rue Seeds Galegin, tannins, chromium. Antidibetic,Sugar destroying agent 24 Hemidesmus indicus, R.Br. (Asclepidaceae) Indian Sarsaparilla Anantmul Root glycosides, denicunine (1) and Blood purifier heminine (4), 25 Madhuca indica, Gmel. (Sapotaceae) Honey tree Mahua Bark Triterpenoid madhucic acid, Antidibetic, Isoflavone madhushazone. 26 Mangifera indica, L. Mango Amba Whole plant Cellular fibre Antidibetic, Astringent, diuretic (Anacardaceae) 27 Momordica charantia, Linn. (Cucurbitaceae) Bitter gourd Karale Fruits,Seeds Sterols,Saponin Charantin,Essential oils. Gout, Rheumatism,Leprosy, 28 Musa paradisica, L. (Musaceae) Banana Keli Latex, Fruit Tannins,eugeno, tyramine,Serotonin, Kidney Failure levarterenol, and dopamine 29 Ocimum sanctum, Linn.(Labiatae) Ocimum Tulasi Root, leaves, Seeds Essential oils,Eugenol,Caryophylline Anti oxidant, Astringent, diuretic, Kidney Purifier 30 Panax ginseng, C. A. Meyer. (Araliaceae) Panax Gensen Root Ginsnoside Antihyperglycemic, Antiobese, Decrease apetite 31 Phyllanthus emblica, L. Indian Goose berry Ambla,Avala Fruit Vit.-C,Tanoide Anaemia, Jaundice, Astringent, (Euphorbiaceae) Dyspepsia 32 Phyllanthus niruri, L. Chik weed Bhui amla Whole plant Phyllanthin Jaundice,Antidibetic, Dysentry. (Euphorbiaceae) 33 Plantago ovate, Husk .(Plantaginaceae) Isbaghul Isabgoal Whole Plant Carnosic Acid, Carnosal diterpenes Inhibition of intenstinal absorption 34 Pongamia glabra, Vent. (fabaceae) Indian Beech Karang Flowers Leucine,Methionine,Oleic Antidibetic, diuretic acid,Linolic acid. 35 Pterocarpus, Roxb. marsupium Indian Kino Tree Bibla Heartwood,Leave, 1-Epicatechin, Fixed oils- Antidibetic, Diarrohea,Antihelmentic. (Papilionaceae) flowers,Gum Liquiritigenin,Catechol 36 Rubia cardifolia, Linn. (Rubiaceae) Indian madder Manjishth Root Resins, Estractive matter, Gum Dropsy, Paralysis, Jaundice 37 Terminalia bellirica, Roxb. Combretaceae) Belliric Myrobalan Behada Fruits Ellagic Acid, Chebulagic Acid, Reduces Sugar in blood, Tonic Fixed oil-Palmitic Acid and Diarrhoea 38 Terminalia chebula, Retz.(Combretaceae) Chebulic Myrobalan Hirda Fruits Tannins, Pyrogallol type a – Glucosidase inhibitor chebulinic Acid 39 Tinospora cordifolia, Willd. Guduchi Gulvel Aerial roors, Stem, Seeds Alkaloids-Berberine, octacosanol Dysentry, Dyspepsia, (Menispermeaceae) Intermittent fever

40 Trigonella Foenum graeceum, L. Fenu greek Methi Aerial parts, Amino Acid 4hydroxy isoleucine Dysentry, Diarrhoea , Flatulence Leave, Seeds (Papilionaceae) 41 Withania Somnifera, L. (Solanaceae) Withania Ashwagandha Dried Roots, Leave, Withanolide, Ginsenosides Diuretic, Hypoglycemic 42 Xanthium Strumarium, Linn. (Asteraceae) Cocklebur or Shankeshvar Stem, Leave, Fruit Bornyl acetate, limonene, Anti Hypoglycemic Burweed B-selinene, Coffeic Acid

Journal of Pharmacy Research Vol.5 Issue 2.February 2012 1001-1003 Rekha R.Deokar et al. / Journal of Pharmacy Research 2012,5(2),1001-1003 ACKNOWLEDGEMENTS: District,Directorate of Govt. Printing ,Stationary and Publications The authors are grateful to all concern rural people including members of Maharashtra State,Bombay,1969,12. 13. Jain S.K. Medicinal Plants,National Book Trust, New forest protection committee, elderly people, traditional medical practitio- Dehli,2001,pp.23-185. ners and local vaidues who have co-operated us. 14. Kapase Harishchandra, Ayurvedic Aushdhi Vanspati, Sun Publica- tion, Pune 2003. REFERENCES 15. Karve P.J. Miracles of Ayu rvedic Herbs, English Edition Publisher, 1. Ambasta SP, Ram,Chandran K, Kashyappa K, Chand R1992. The (India), 2005,pp.27-29,103-165. Useful Plants of India. New Delhi :Publications and Information 16. Kirthikar K.R., Basu B.P., Indian Medicinal Plants, Vol.1st - 4th, Directorate, CSIR. Periodical Experts, New Dehli, 1975. 2. Bal SN 1942.Useful plants of Mayurbhanj State in Orissa. Rec Bot 17. Kirthikar K.R., Basu B.P., Indian Medicinal Plants, Vol.3rd, Edition Surv. India, 6:1-119. 2nd,Periodical Experts , New Dehli,1991. 3. Agarwal S.S.,Tamrakar B.P.,Paridhavi M. Clinically useful Herbal 18. Loksatta, 2004, www.loksatta.com Drugs,1st Edition , Ahuja publishing House,Delhi,2005,pp.27-300. 19. Nadkarni K.M., Indian Materia Medica, Vol. I, Popular Prakashan, 4. Agarwal S.S.,Paridhavi M. Herbal Drug Technology, 1st Edition ,Uni- , 2002, pp. 4-5, 23-28, 103-108, 284-864, 1001-1243. versity Press, Hyderabad, pp. 69,90,104,106. 20. Panigrahi A.K. and Panigrahi A. (S), Glossary of Useful and Impor- 5. Anonymous, Quality Standards of Indian Medicinal Plants,Vol.1st tant Plants, New Central Book Agency, 2000. ,Indian Council of Medical Research ,New Dehli,2003,pp.95-248. 21. Satyanarayana T, Katyayani B.M., Latha H.E., Mathews A.A. and 6. Anonymous,Wealth of India,Raw Materials,1992, Vol.1st -5th ,Coucil Chinna E.M., Hypoglycemic and antihyperglycemic effect of alco- of Scientific and Industrial Research ,New Dehli,1962. holic extract of Euphorbia leucophylla and its fractions in normal 7. Chandler RF, Freeman L, Hopper SN 1979. Herbal remedies of and in alloxan induced diabeticrat, Phcog Mag 2006, 244. maritime Indians. J Ethnopharmacol,1: 49-54. 22. Sharma P.C., Murthy K.S., Bhat A.V., Narayanappa D., Prem K. 8. Debra H.J., Managrmrnt of Diabetes Mellitus Edn. 2, Perspective of 1985-1986.Medicinal –l ores of Orissa-I, Skin Diseases. Bull Medico- care across the life span, 3, 1991. ethnobot. Res, 6: 93-101. 9. Dey K.L. The Indigenous Drug of India, The Chronia Botanica, 23. Tarafdar CR 1986. Ethnobotany of Chhotnagpur, less known and New Delhi, 1973, pp. 24-38 unknown 38 medicinal plants used by the tribals. Folklore, 27: 119- 10. Fairbairn JW 1980. Perspective in research on active principles of 122. traditional herbal medicines, A botanical approach : identifica- 24. Theodore Cooke, The Flora of The Presidency of Bombay, Botani- tion and supply of herbs. J Ethnopharmacol, 2: 99-106. cal Survey of India, Calcutta, Vol. I, II, III. 1967. 11. Gazetteer of India, General Climate , Maharashtra State , Sangli 25. Times of India, 2004, www. timesofindia.indiatimes.com District,Directorate of Govt. Printing ,Stationary and Publications 26. Zaidi M.A., Crow S.A. 2005. Biologically active traditional me- Maharashtra State,Bombay,1969,1. dicinal herbs from Balochistan, Pakistan. J. Ethnopharmacol, 96: 12. Gazetteer of India, General Climate , Maharashtra State , Sangli 331-334.

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Journal of Pharmacy Research Vol.5 Issue 2.February 2012 1001-1003