ADAMTS4 Antibody Cat. No.: 29-597
ADAMTS4 Antibody
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human ADAMTS4.
TESTED APPLICATIONS: ELISA, IHC, WB
ADAMTS4 antibody can be used for detection of ADAMTS4 by ELISA at 1:62500. ADAMTS4 APPLICATIONS: antibody can be used for detection of ADAMTS4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate
PREDICTED MOLECULAR 37 kDa, 90 kDa WEIGHT:
September 30, 2021 1 https://www.prosci-inc.com/adamts4-antibody-29-597.html Properties
PURIFICATION: Antibody is purified by peptide affinity chromatography method.
CLONALITY: Polyclonal
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.
CONCENTRATION: batch dependent
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: ADAMTS4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
OFFICIAL SYMBOL: ADAMTS4
ALTERNATE NAMES: ADAMTS4, ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
ACCESSION NO.: AAH30812
PROTEIN GI NO.: 21410063
GENE ID: 9507
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal BACKGROUND: domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
ANTIBODIES FOR RESEARCH USE ONLY.
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