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TheTHE SOCIETY OF BIOLOGY MAGAZINE ■ ISSN 0006-3347Biologist ■ SOCIETYOFBIOLOGY.ORG VOL 60 NO 4 ■ AUG/SEP 2013 CREATING A BUZZ The trend for city hives and what it means for our bees INTERVIEW TAXIDERMY MICROBIOLOGY IMRAN KHAN STILL LIFE EXTREME SPECIES Meet the rising star The resurgence of Organisms that change of British science a forgotten craft the way we view life New from Garland Science Second Edition The Biology of Cancer Robert A. Weinberg Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of July 2013 • 960pp • 584 illus discovery and provide insights into the Hb: 978-0-8153-4219-9 • £105.00 conceptual foundation underlying modern Pb: 978-0-8153-4220-5 • £55.00 cancer biology. Every copy of the book comes with an updated “Pathways in Human Cancer” poster and a DVD-ROM containing the book’s art program, a selection of movies, audio file mini-lectures, Supplementary Sidebars, and a Media Guide. TABLE OF CONTENTS: 1. The Biology and Genetics of Cells and Organisms 2. The Nature of Cancer 3. Tumor Viruses 4. Cellular Oncogenes 5. Growth Factors, Receptors, and Cancer 6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer 7. Tumor Suppressor Genes 8. pRb and Control of the Cell Cycle Clock 9. p53 and Apoptosis: Master Guardian and Executioner 10. Eternal Life: Cell Immortalization and Tumorigenesis 11. Multi-step Tumorigenesis 12. Maintenance of Genomic Integrity and the Development of Cancer 13. Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis 14. Moving Out: Invasion and Metastasis 15. Crowd Control: Tumor Immunology and Immunotherapy 16. The Rational Treatment of Cancer www.garlandscience.com/tboc2 TheBiologist THE SOCIETY OF BIOLOGY MAGAZINE Volume 60 No 4 August/September 2013 Contents 24 12 GET TOMORROW’S PANIC FREE! COUPON INSIDE DAILY PANIC 16 MONDAY, 12th August, 2013 www.dailypanic.co.uk WEATHER Grim 50p NEW CANCER ALERT ON JUST ABOUT ANYTHING By Andrew Hack Chief Health Worry Writer INSANE residents forced from their homes and businesses by the UK’s worst ever fl oods were yesterday returning to survey the damage. The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare. The once busy and vibrant streets are fi lthy and reek of sewage – and it is predicted that the recovery could take months, if not years. The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare. The once busy and vibrant streets are fi lthy and reek of sewage – and it is predicted that the recovery could take months, if not years. Scare stories 28The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare. The once busy and vibrant streets are fi lthy and reek of sewage – and it is predicted that the recovery could take months. The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare. The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare. …AND CATS ARE DEADLY TOO The rain has stopped and water levels have fallen in most areas – but there is no happy homecoming for the Glaswegians caught up in this nightmare Why your family moggy is bad news where the rain has stopped and water has receded. Turn to page 5 SEE PAGE 9 IN THIS ISSUE 8 Thought crime 16 Back from the dead ■ ■ ■ News TheTHE SOCIETY OF BIOLOGY MAGAZINE ISSN 0006-3347Biologist SOCIETYOFBIOLOGY.ORG VOL 60 NO 4 AUG/SEP 2013 Joseph Jebelli considers Tom Ireland looks at the 4 Society news the implications of using resurgence in taxidermy. neuroimaging in the 34 Members criminal justice system. 20 The outer limits 37 Branches Simon Toomey on finding life 9 The problem with postdocs at the world’s extremes. CREATING A BUZZ Regulars The trend for city hives and what it means for our bees INTERVIEW TAXIDERMY MICROBIOLOGY IMRAN KHAN STILL LIFE EXTREME SPECIES Improving career options for Meet the rising star The resurgence of Organisms that change 3 Nelson’s column of British science a forgotten craft the way we view life postdoc researchers. 24 Imran Khan Inset image of stuffed 10 Policy update The new chief executive of the animal: Jack Spicer Adams, 32 Spotlight www.jackspiceradams.com 12 To bee or not to bee British Science Association 42 Reviews Karin Alton and Francis talks to Sue Nelson. 45 Biofeedback Ratnieks assess the rise of urban beekeeping and 28 What's your poison? 46 Museum piece what it means for the future Dr Barbara Hall explores the 47 Crossword of honey bees. poisons that are all around us. 48 Final word Vol 60 No 4 / THE BIOLOGIST / 1 THE BIOLOGIST Vol 60 No 4 August/September 2013 Contacts EDITORIAL STAFF Allan Jamieson BSc PhD CBiol FSB Society of Biology Director of Membership, Marketing Catherine Jopling BSc PhD MSB Charles Darwin House, and Communications 12 Roger Street, Susan Omar BSc PGCE CBiol CSci MSB MRSPH FRGS Jon Kudlick London WC1N 2JU Editor Leslie Rose BSc CBiol FSB FICR MAPM Tel: 020 7685 2550 Sue Nelson Fax: 020 3514 3204 Managing Editor [email protected] Tom Ireland MSB ADVISORY PANEL www.societyofbiology.org [email protected] Ian Clarke, Horticulture Research International, UK Communications Assistant Clive Cornford, Unitec, Auckland, New Zealand Views expressed in this magazine are Karen Patel AMSB Sharon Grimster, BioPark, UK not necessarily those of the Editorial [email protected] Board or the Society of Biology. Marios Kyriazis, For membership enquiries call 0844 858 9316 Biogerontologist and anti-ageing physician, UK © 2013 Society of Biology [email protected] Alan Lansdown, Imperial College London, UK (Registered charity no. 277981) For subscription enquiries call 020 7685 2556 Walter Leal Filho, [email protected] Hamburg University of Applied Sciences, Germany The Society permits single copying Don McManus, Bancroft Centre, Australia of individual articles for private study or research, irrespective of where EDITORIAL BOARD Peter Moore, King’s College London, UK J Ian Blenkharn MSB FRSPH the copying is done. Multiple copying Brian Osborne, Australia of individual articles for teaching Phil Collier MSc PhD CBiol FSB FLS FHE John Scott, University of Leicester, UK purposes is also permitted without Cameron S Crook BSc MPhil CBiol MSB MIEEM FLS Robert Spooner-Hart, University of specific permission. For copying or Rajith Dissanayake MSc PhD FZS AMSB Western Sydney, Australia reproduction or any other purpose, Catherine Duigan BSc PhD FSB FLS written permission must be sought from Kathleen Weathers, Institute of the Society. Exceptions to the above are John Heritage BA DPhil CBiol FSB Ecosystem Studies, USA those institutions and non-publishing Sue Howarth BSc PhD CBiol FSB Steve Wilson, pfizer Animal Health organisations that have an agreement or licence with the UK Copyright Licensing Agency or the US Copyright Clearance Centre. Access to the magazine is available online; please see the Society’s MEDICAL RESEARCH CANCER website for further details. TheBiologist THE NUCLEAR The Biologist is produced on behalf OPTION of the Society of Biology by Dr Ulli Köster explains how rare radioisotopes, made in world famous physics labs such as CERN, could Think publishing Ltd. A WINDOW provide new treatments for cancer ILL, to double up as factories to GRAPHY BIO support production of the rare 124-128 Barlby Road aws, Oddjob, Dr No… in the James Bond films we have isotopes needed in these treatments. If this seems surprising, that is seen the famous British spy J because it is. The ILL’s High Flux eliminate some notorious villains. Reactor was developed to provide In the medical world, the treatment neutrons not for the production of of cancer is turning to its own London W10 6BL rare radioisotopes, but to study the group of special agents, displaying structure of matter. Yet biological a keen sense to seek out danger materials on the nanometre scale, and a deadly efficiency in bringing Dr Ulli Köster is a such as proteins, viruses and cell down a very different, but equally nuclear physicist at the Institut membranes, which are naturally ON THE LIFE treacherous foe. Laue-Langevin The source of interest is a new rich in light elements, are ideal for www.thinkpublishing.co.uk in Grenoble. His analysis with neutrons, and today generation of radiopharmaceuticals interests range biologists work alongside neutron based on a group of radioactive from fundamental scientists to decipher their structure isotopes with properties that make science to applied and work out how they carry out them ideal for more targeted nuclear physics for cancer treatment. their body functions. cancer treatment. The hope is that 020 8962 3020 these powerful weapons could not Homing beacons, time bombs only improve the success rates of and detonations treatment and diagnosis through Most primary stage cancers can be personalised medicine, but also treated using surgery and radiation reduce some of the nasty side effects therapy but, for some time, once associated with existing procedures.