CHRNA9 Antibody Cat. No.: 61-055

CHRNA9 Antibody

Western blot analysis of lysate from Daudi cell line, using CHRNA9 Antibody at 1:1000.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 8-42 amino acids from the N-terminal region of human CHRNA9.

TESTED APPLICATIONS: Flow, WB

For FACS starting dilution is: 1:25 APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 55 kDa WEIGHT:

September 24, 2021 1 https://www.prosci-inc.com/chrna9-antibody-61-055.html Properties

This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CHRNA9

Neuronal subunit alpha-9, Nicotinic acetylcholine receptor subunit ALTERNATE NAMES: alpha-9, NACHR alpha-9, CHRNA9, NACHRA9

ACCESSION NO.: Q9UGM1

PROTEIN GI NO.: 308153406

GENE ID: 55584

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may BACKGROUND: activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.

REFERENCES: 1) Sgard F.,et al.Mol. Pharmacol. 61:150-159(2002).

2) Lustig L.R.,et al.Cytogenet. Genome Res. 98:154-159(2002).

3) Hillier L.W.,et al.Nature 434:724-731(2005).

4) Nguyen V.T.,et al.Am. J. Pathol. 157:1377-1391(2000).

September 24, 2021 2 https://www.prosci-inc.com/chrna9-antibody-61-055.html ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 24, 2021 3 https://www.prosci-inc.com/chrna9-antibody-61-055.html