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( β iaca Support Financial 125 https://doi.org/10.1017/S0029665115004152 clst dp hi ciiist condi- to activities their adapt to -cells ) . Conclusion . IPaddress: ( 123 ) eyeeatgenetic elegant very A . β 170.106.33.22 -cell-speci , on fi lncRNA c ( ( 125 24 Sep2021 at13:14:04 98 , 121 ) .This β , .Regazzi R. 122 -cell ) . 3 esom ,Cua ,Afs F Arfuso V, Cruzat P, Newsholme 13. 2 rnk ,MtcisyF aiauS (2013) SR Madiraju & FM Matschinsky M, re- fuel Prentki beta-cell: 12. islet The (2008) M Prentki & CJ Nolan 11. and homeostasis glucose of Physiology (2012) E Ferrannini 10. 7 hrn 21) ri lcs esn n erlregula- neural and sensing glucose Brain (2011). B Thorens 17. and sensing nutrient Intestinal (2015) H Daniel & T Zietek 16. 4 io ,Rve A oa JC Jonas MA, Ravier P, Gilon 14. 5 eeveP,Pois ,She AJ Scheen G, Paolisso PJ, Lefebvre 15. .R,A .T n .J erhdteltrtr n wrote and literature the searched J. manuscript. C. and the T. R. A. R., R. None. by and Diabète. 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Lecture Minkowski men. eaoi inln nfe-nue nui secretion. insulin fuel-induced Metab in signaling Metabolic vulnerable. 285 and sponsive diabetes. 2 type Am and North 1 Clin type Metab in therapy insulin stresfrteteteto pe atonetnldisor- gastrointestinal upper of treatment ders. the for targets as xsi acetcsceinadaptt control. appetite and Pharmacol secretion pancreatic in axis food. tolerate Behav us helps release insulin compensatory inadmetabolism. and tion re euaini edn ilg:cpai hs responses. phase cephalic biology: Appetite feeding in regulation satisfaction. to Motil satiation from nication: 25 ino nui n lcgnsecretion. glucagon and 13 insulin of tion 381 control. glucose blood implications. 443 pharmacological and ehnsso h siltoso nui secretion insulin of and oscillations the of mechanisms isadmnrl neeg eaoimadwell-being. and metabolism Res Med energy Int in J minerals and mins fislnadguao ees:pyilgclsigni physiological release: glucagon and insulin of . fl ,1 up.1 82 1, Suppl. , xs hi oei ieto n osberlsi absorp- in roles possible and digestion in role their exes: – – – R105 , nvivo in 452. 291. 388. – a e rgDiscov Drug Rev Nat 13. 20 103 18 up.1 64 1, Suppl. , 50 162 , ,44 – . 54 194 , R120. 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