FEBRUARY 7 • 2014 PUBLISHED FOR THE USC HEALTH SCIENCES CAMPUS COMMUNITY VOLUME 1 • NUMBER 3 Renowned eye expert named Dept. of Ophthalmology chair

‘Keck Medicine Keck School of Medicine significant contributions to and community network of USC has named one the field, Varma has been a development with the Keck of USC is known of its own, Rohit Varma, funded researcher for the School of Medicine of USC for its pioneering MD, MPH, to become past 20 years by the National to expand the eye care efforts in vision chair of the Department of Eye Institute, part of the network. Ophthalmology and director National Institutes of Health “Dr. Varma is an interna- research and of the USC Eye Institute (NIH). tionally recognized clinician- innovative as well as to serve as He is the principal inves- scientist, translational solutions to professor of ophthalmology tigator of the researcher and educator,” managing eye and preventive medicine Latino Eye Study (LALES), said Carmen A. Puliafito, and hold the Grace and Multi-Ethnic Pediatric MD, MBA, dean of the disease and I Emery Beardsley Chair in Eye Diseases Study (ME- Keck School of Medicine.

am dedicated Ophthalmology. Urfalian Van PEDS), African-American “His vital work protecting to continuing Varma, who is currently Rohit Varma Eye Disease Study and and promoting vision health this legacy of chair of the Department of the Chinese-American Eye for all Americans and his Ophthalmology and Visual of the glaucoma service, Study in addition to his primary epidemiological excellence.’ Sciences at the Illinois Eye ocular epidemiology center studies on blindness and research, which has focused and Ear Infirmary at the and clinical trials unit. vision impairment for the on two of our most vulner- —Rohit Varma, chair University of Illinois at Chi- An accomplished physi- World Health Organization. able populations: minority of the Keck School cago College of Medicine, cian/scientist, Varma is Varma’s experience with children and seniors, go of Medicine returns to the Keck School recognized worldwide national and international beyond exceptional medi- Department of of Medicine where he previ- as a visionary leader in organizations will aid in his cine. We’re proud to have Opthalmology ously served as professor of the epidemiology of eye additional role as associate him return to Keck Medical ophthalmology and director diseases. Among his many dean for strategic planning See VARMA, page 3 Helen Hislop, influential former chair of physical therapy, dies at 84

By Hope Hamashige At USC, Hislop developed the first 1950s, where she first worked with the sciences and clinical work and Helen Hislop, PhD, a pioneering PhD program in physical therapy polio patients. She went on to work the types of positions they held. former chair of Biokinesiology and in the United States and one of the at Yale University Hospital She was later asked to edit Physical Therapy, a division at the first Doctor of Physical Therapy and later finished a master’s the journal, a position she Ostrow School of Dentistry of USC, programs. degree in physiology at held for much of the 1960s, died on Nov. 15 in North Carolina at She also embraced evidence-based the University of Iowa. which gave her a voice in the age of 84. Hislop spent 30 years learning, integrating the practice After teaching for several shaping the direction of the at USC, heading the division from of physical therapy with top-level years, she completed her profession. 1975 to 1998. scientific research, which has since PhD in physiology at the In 1968, Hislop came In a message to colleagues at USC, become the standard at the division University of Iowa. to USC while working James Gordon, EdD, current chair and for all physical therapy programs Early in her career, as director of the of the division, wrote, “More than in the United States. Hislop conducted research Rehabilitation Research and anyone, she was responsible for the Another of her innovations was the on the state of physical Training Center at Rancho growth of our research programs, the creation of clinical specializations therapy education Helen Hislop Los Amigos Hospital, formation of our clinical programs, within the division curriculum. She that would serve as the which had an affiliation and the excellence of our education also developed the clinical internship foundation of the reforms she later with several departments at USC, programs. She was a true visionary, programs, which transformed into instituted at USC. That study, including physical therapy. and she is recognized as a giant in the physical therapy residencies while published in the Journal of the Hislop redesigned the clinical physical therapy profession. Every she was at USC. American Physical Therapy Association education for division students, physical therapist, not just those of us Hislop studied physical therapy at (APTA), looked at the level of offering a one-year internship for at USC, benefits from her legacy.” the University of Iowa in the early physical therapists’ preparation in See HISLOP, page 2

Pres. Nikias to address faculty Feb. 11

USC President C.L. Max Nikias will present his annual address to the Health Sciences Campus faculty on Feb. 11 from 7:30-8:30 a.m. at the Aresty Conference Center. All faculty are welcome and encouraged to attend the event and the 7 a.m. breakfast immediately preceding. To RSVP, visit: usc. edu/esvp and use code Sara Reeve Sara “HSC11.” HAPPY (LUNAR) NEW YEAR! — Members of the Asian Pacific American Medical Student Association dance in colorful costumes at Harry and Celesta Pappas Quad on Jan. 30 to celebrate the beginning of the lunar new year and the Chinese Year of the Horse. FEBRUARY 7 • 2014 Viral microRNAs responsible for causing AIDS-related cancer

By Alison Trinidad KSHV never show any symptoms, stay alive and become malignant when For the first time, scientists and Kaposi’s sarcoma is a persistent problem infected with the virus. engineers have identified a critical in areas where HIV infection is high Using advanced genomic methods, cancer-causing component in the and access to HIV therapy the researchers also found virus that causes Kaposi’s sarcoma, the is limited. More than 90 that the microRNAs target the ‘We have most common cancer among HIV- percent of the population in IκBκ protein and the NF-κB identified a infected people. The discovery lays the some areas of Africa shows cellular pathway, both of which foundation for developing drugs that signs of KSHV infection, are associated with cancer mechanism by prevent Kaposi’s sarcoma and other according to the American development. which these tiny related cancers. Cancer Society. “Our results suggest that this “The mechanism behind the Gao and colleagues from cluster of KSHV microRNAs viral molecules Kaposi’s sarcoma-associated herpesvirus the University of Texas at and their regulated NF-κB cause the cells (KSHV) that causes healthy cells San Antonio (UTSA) and pathway may be potential to become malignant is not well University of Texas Health S. J. Gao targets for new therapeutics of to become understood despite two decades of Science Center at San KSHV-related cancers,” said intensive studies,” said S. J. Gao, PhD, Antonio studied KSHV using a rat stem Gao, who is also a member of the USC malignant.’ professor of molecular microbiology cell model they developed in 2012. Norris Comprehensive Cancer Center. and immunology at the Keck School Until then, researchers had been unable “Several of the microRNAs appear to —S. J. Gao, of Medicine of USC and principal to study the virus because most healthy have redundant functions, so targeting investigator of the study. “This is the cells, once infected with KSHV, died their common pathways might be a PhD, professor first time that a viral factor has been before turning into cancer cells. more feasible approach. It would be of molecular shown to be required for KSHV-induced In this study, which appeared in the interesting to test them in the KSHV- microbiology and malignant transformation. We have Dec. 26 edition of the peer-reviewed induced Kaposi’s sarcoma model.” immunology at identified a mechanism by which these journal PLOS Pathogens, the team Yufei Huang, PhD, professor of tiny viral molecules cause the cells to identified a cluster of viral microRNA electrical and computer engineering at the Keck School of become malignant.” molecules that are necessary to UTSA, is the study’s co-corresponding Medicine of USC Distinguished by dark lesions on the transform healthy cells into cancerous author. Other USC authors include skin, Kaposi’s sarcoma most commonly ones. When this microRNA cluster was researchers Ying Zhu, PhD, and Tiffany develops in people who are infected suppressed, the cells died after they Jones, PhD. Their work was supported with KSHV and also have compromised were infected with KSHV. Flipping by the National Institutes of Health immune systems. the switch and turning the cluster back (grants CA096512, CA124332, and Although many people infected with “on,” however, allowed the cells to CA177377).

USC partners with advocacy organization to improve heart health among Latinos

By Paul Karon effective at communicating evidence-based curriculum The promotoras then and director of SC CTSI’s A public education pro- key health information. was developed by the NIH’s organized 11-week heart- Community Engagement, gram that trained and fielded Lourdes Baezconde- National Heart, Lung, and health courses based on said, “Promotoras bring a cadre of health mentors Garbanati, PhD, professor of Blood Institute (NHLBI) to the curriculum, involving unique expertise and skill in California significantly preventive medicine at the address health disparities in Latinos who lived in their sets that help researchers boosted Latino residents’ Keck School of Medicine, underserved and minority communities in urban Los to create tailored, targeted knowledge of everything served as principal communities. Angeles County and rural interventions. This is a great from cholesterol and investigator on the study. Promotoras were trained Kern County. The study example of an innovative diabetes to the importance Collaborators included to provide culturally and was designed to explore strategy that brings research- of nutrition and exercise, a Visión y Compromiso, linguistically relevant health the value of the promotora ers and the community to- USC study showed. an advocacy organization information and help to model in reducing the gether to improve the health The study, by the devoted to improving people within their com- disproportionately high of our diverse community.” Southern California Clinical knowledge and access to munities. As members of rates of heart disease and Based on data gathered and Translational Science health care for California’s the community themselves, other health concerns through questionnaires Institute (SC CTSI), showed native-born and immigrant promotoras were able to among Latinos in those administered at the start and that specially trained Latino communities. leverage personal contacts, communities. completion of the courses, “promotoras” — community During the SC CTSI proj- trust and respect to address By the time the study was investigators found that resi- members who act as ect, the study team trained sensitive topics, counter completed, the promotoras dents who took the work- health-oriented helpers and 25 promotoras in a heart- misinformation and advocate had engaged a total of 730 shops improved in several liaisons to their neighbors health curriculum called for quality care, according to residents in the courses in 49 areas of lifestyle and health and communities — were “Su Corazón, Su Vida.” The advocates. workshops between the two knowledge, such as causes counties studied. and effects of diabetes, as Michele Kipke, PhD, well as cooking habits and co-director of SC CTSI frequency of exercise. HSC News Next Issue: Feb. 21 HISLOP: USC leader shaped a profession

Continued from page 1 movement. Biokinesiology HSC News is published for the faculty, staff, students, volunteers and visitors in the University select students. was integrated into the of Southern California’s Health Sciences campus community. It is written and produced by the During that year, students division’s curriculum during Health Sciences Public Relations and Marketing staff. Comments, suggestions and story ideas did three rotations at three that time and also became are welcome. Permission to reprint articles with attribution is freely given. local institutions, including part of the division’s formal Rancho Los Amigos and Los name. Associate Vice President, Health Sciences Public Relations and Marketing: Angeles County Hospital, It took another decade Deborah S. Fullerton now called LAC+USC to plan, but she also Executive Director of Creative Services: Tom DeSanto Medical Center. successfully launched By 1978, the program at USC’s DPT program, which Assistant Director of Publications: Sara Reeve USC accepted its first PhD graduated its first class in students and awarded its 1998, the year Hislop retired Editor: Jon Nalick first PhD in 1984. In 1993, and moved to Durham, Contributors: Amy E. Hamaker, Hope Hamashige, Paul Karon, Carol Matthieu, Leslie Ridgeway Hislop introduced the North Carolina. and Alison Trinidad concept of biokinesiology, Donations in Hislop’s which studies the interplay honor may be made to the Vice President, Public Relations and Marketing: Brenda Maceo between molecular and cell Helen Hislop Endowed biology of muscles, bones Scholarship Fund, which Phone: (323) 442-2830 Fax: (323) 442-2832 and joints and how that supports USC Doctor of Email: [email protected] Web: theweekly.usc.edu influences the mechanical Physical Therapy students at and behavioral aspects of USC, at http://usc.edu/17u. Calling all Keck School faculty: Cast your vote for USC

U.S. News & World Report Doximity, a new online currently listed as “USC ranks many of our excellent physician network. Keck Hospital” and “USC clinical departments among To vote online, physicians Norris Cancer Hospital.” For the top programs in the need to register for a free ophthalmology, physicians country. These rankings account or update their may be asked to choose are an important marker profile with Doximity. “USC Eye Institute” or to that communicates the high Physicians may already have type in their vote. quality of our patient care a profile because Doximity Faculty member votes and medical research to the pulls information from are important. “If you are public. physician databases. invited, please vote,” said Each program’s reputation By visiting www.doximity. Carmen A. Puliafito, MD, Leslie Ridgeway among physicians is a vital com, physicians can establish MBA, dean, Keck School NEIGHBORHOOD ACADEMIC INITIATIVE KICKS OFF component of scoring. In or activate their accounts of Medicine of USC. “I SATURDAY ACADEMY—The USC Neighborhood Academic previous years, U.S. News quickly by entering their urge you to participate Initiative (NAI) launched its Saturday Academy on Jan. 18, sent its survey to a small names and clicking on “Find in the survey, which is so expanding to include nearly 100 sixth graders who live near the Health Sciences Campus. The NAI is a seven-year enrichment group of board-certified My Profile.” important to recognizing the program preparing low-income, minority students living in specialists across the country. After registration, top hospitals and clinical neighborhoods surrounding USC’s campuses for success at a This year, U.S. News has physicians may receive an programs in the country.” college or university. The kickoff event gave students and parents announced it will expand the invitation to participate Time is of the essence. a chance to meet with NAI alumni, who spoke to the students survey to reach 50,000 board- in the U.S. News survey The U.S. News survey is about their experiences with the program and described how it certified physicians using an to rank programs. Please underway and will continue helped them succeed in higher education. Above, the USC Trojan online voting process through note that USC hospitals are through Feb. 10. Marching Band plays at the event, held at the USC Galen Center. VARMA: Hails USC’s ‘pioneering efforts in vision research,’ eye disease treatment

Continued from Page 1 together education and Institute at Keck Medical the American Academy in Biomedical Sciences, a School of USC and name training, research and School of USC,” said Varma. of Ophthalmology Public tenured University Profes- him as chair of our oph- patient care, Dr. Varma will “Keck Medicine of USC Health Committee and sor in three departments: thalmology department to help us lead the way during is known for its pioneering served on the board of the ophthalmology, biomedical continue our leadership in a time of significant health efforts in vision research Scientific Counselors of the engineering, and cell and vision training, research and care transformation.” and innovative solutions to National Eye Institute. neurobiology. Humayun will clinical practices.” More than 4.1 million managing eye disease and I Having earned his medical continue to lead the oph- During Varma’s time Americans over age 40 suffer am dedicated to continuing degree at the University of thalmology department in at USC, the Department from some vision impair- this legacy of excellence and Delhi, India, Varma com- an interim role until Varma of Ophthalmology was ment including more severe helping guide the depart- pleted his residency at assumes his role as chair this a pioneer in population- eye diseases such as glauco- ment to new heights.” Johns Hopkins Hospital in summer. based studies that have ma (2.7 million) and almost Varma has more than 219 Baltimore as well as earning “We are especially grate- provided substantial data on 1.3 million with complete publications in peer-re- a master’s in public health ful to Dr. Humayun for the frequency and impact blindness. Focusing on the viewed ophthalmic journals from Johns Hopkins Uni- providing interim leadership of major eye diseases, as changes in the optic nerve in and has co-written two oph- versity. He completed two and are pleased to sup- well as possible preventive glaucoma, Varma has helped thalmic books, Essentials of glaucoma fellowships, one port his goals of returning and therapeutic strategies pioneer the development Eye Care: The Johns Hopkins at the Wills Eye Hospital in more of his focus to his necessary to eliminate them. of imaging techniques that Wilmer Handbook and The Philadelphia and the other at ground-breaking research Varma also has established aid in the early diagnosis of Optic Nerve in Glaucoma. the University of Southern programs,” Puliafito said. an international reputation glaucomatous optic nerve His numerous awards California. “Through his work in in new imaging techniques damage. He also was in- include Research to Prevent Mark S. Humayun, MD, advanced engineering, Dr. for detecting and treating volved in developing unique Blindness Career Develop- PhD, who has served as Humayun will continue to glaucoma. implantable intraocular ment, Sybil B. Harrington interim chair of the Depart- ensure Keck Medical School “Dr. Varma is a perfect pressure (IOP) sensors and Scholar, American Academy ment of Ophthalmology of USC’s critical contribu- example of the world-class drainage devices that hold of Ophthalmology Senior and director of the USC tions to vision disease and talent we attract at Keck the promise for curing or at Achievement Award, Glau- Eye Institute, will continue therapies.” Medicine of USC,” said least controlling glaucoma. coma Research Foundation as co-director for USC Eye Humayun is internation- Thomas Jackiewicz, senior “I am deeply honored to President’s Award and Best Institute and as director of ally known for his work on vice president and CEO for have been selected as the Doctors in America. the Institute for Biomedical the Argus II artificial retina USC Health. “By foster- chair of the Department He serves on the Institute Therapeutics, director of implant designed to restore ing the best in academic of Ophthalmology and of Medicine Roundtable on sensory sciences initiatives, sight to those blinded by medicine where we bring director of the USC Eye Health Disparities, chairs the Cornelius J. Pings Chair macular degeneration.

HSC NEWSMAKERS

The January 2014 edition of Physician more. “Nothing pounding. I use an exercise bike; School of Engineering. Agus discussed the practical Magazine featured a story about Keck Medicine you’re still putting weight on your joints, you get the value to corporations taking care of their employees’ of USC opening a new downtown outpatient clinic. aerobics, but it’s not like a treadmill,” he said. health. CBS News “This Morning” also highlighted the The clinic opening also was covered by Los Angeles book, in which Agus makes recommendations for Downtown News. A Jan. 13 story on Xconomy.com noted that patients to manage their own health. “Health is going angel investors Rock Health named Leslie Saxon, to change from the ground up, not the top down,” A Jan. 17 article in featured MD, professor of clinical medicine at the Keck School, Agus said. “I wrote a book with all the tenets and the a U.S. Surgeon General’s report edited by Jonathan among its “Top 50 in Digital Health,” individuals “who rules so you can go in empowered.” Samet, MD, Flora L. Thornton Distinguished Chair of led the pack in making the largest impact on digital Preventive Medicine at the Keck School. The report health in 2013.” A Jan. 8 broadcast on CBS News Los Angeles linked cigarette smoking with various kinds of deaths affiliate KCBS-TV quoted Daniel Stram, MPH, and illnesses. Smoking reduces the effectiveness of A Jan. 9 broadcast of “The Doctors” featured an PhD, professor of preventive medicine at the Keck insulin, causing diabetes, Samet said. It also affects interview with Armand Dorian, MD, clinical associate School, about the risks associated with eating the liver and triggers inflammation, causing arthritis. professor of emergency medicine at the Keck School, seafood. discussing bizarre stories from the emergency room. A Jan. 16 column in ran a Q&A A Jan. 8 story in the La Cañada Valley Sun featured with C. Thomas Vangsness, Jr., MD, professor of A Jan. 8 video report on The Wall Street Journal a story about the first baby delivered at USC Verdugo orthopaedic surgery at the Keck School, about his featured A Short Guide to a Long Life by David Hills Hospital in 2014. “It’s kind of like you share the book “The New Science of Overcoming Arthritis,” co- Agus, MD, director of the USC Westside Norris Cancer holiday (with them),” said Missy Stehlin, RN, interim written with Greg Ptacek. Vangsness recommends Center and director of the USC Center for Applied clinical director of perinatal services at USC-VHH, that people with arthritis exercise to work their joints Molecular Medicine at the Keck School and Viterbi about holiday babies. “It’s exciting for all of us.” FEBRUARY 7 • 2014

Massry Foundation’s $175,000 grant Calendar of Events supports seven KSOM research scholars Sunday, Feb. 9 Friday, Feb. 14 By Leslie Ridgeway 8 p.m. Cinderella Cares 8 a.m. Saban Research With a goal of helping Foundation’s Comedy for Institute Seminar. “Youth young researchers launch Cure. Proceeds benefit lung Violence: The Ultimate cancer research at USC Health Disparity,” Edward M. their careers, the Meira and Norris. Comedy Store, 8433 Barksdale, Jr., Case Western Shaul G. Massry Founda- W. Sunset Blvd. LA 90069. Reserve School of Medicine. tion has provided a $175,000 $12.00. Tickets and info: Saban Research Building, gift to the Keck School of www.cinderellacares.com. First Floor Auditorium, CHLA. Info: cmillan Medicine of USC Dean’s Monday, Feb. 10 @chla.usc.edu Fifth-Year Research Scholars Noon. Keck School program. of Medicine Research 9 a.m. – 3:30 p.m. Keck With this gift, seven School of Medicine Seminar Series. “Epigenetic fourth-year medical students Mechanisms in Asthma Workshop on 3D have the opportunity to and Food Allergies: From Neuroimaging. “Structural Air Pollutants to Food and Diffusion Brain Imaging focus on research projects for Allergens,” Kari C. Nadeau, for Medical Image Analysis in a year after graduation from Stanford University 3D Slicer,” various speakers, medical school. USC. SSB, Room 105. Info: School of Medicine. Aresty Fifth-year scholars receive Auditorium. Info: maryjane. [email protected] Amy Hamaker Amy [email protected] a stipend of $25,000 each to Noon. USC School of continue their research. The Shaul G. Massry (left) presents Keck School of Medicine Dean Carmen A. 3 p.m. – 5 p.m. Southern Pharmacy Seminar $175,000 gift is $75,000 more Puliafito with a check to support the Fifth-Year Research Scholars program. California Clinical and Series. “Potent Antibody than last year’s gift, giving Drug Conjugates: From Translational Science three more students an op- the division of nephrology at disease and what causes Institute. “How to Write a Early Stage Research to Manuscript,” Jon Samet, a Clinically Approved portunity for support. the Keck School from 1974 it. You need investigators USC. Harkness Auditorium. Drug,” Peter Senter, “I believe that a student to 2000, and has received to search for the causes of RSVP: [email protected] Seattle Genetics. PSC who has finished four years honorary doctorates from 14 disease.” Room 104, John Stauffer of medical school and is European universities. Keck School Dean Car- Tuesday, Feb. 11 Pharmaceutical Sciences Center. Info: weishen ready to postpone his or He has published more men A. Puliafito, MD, MBA, 7:30 a.m. – 9:30 a.m. @usc.edu her career is motivated to than 600 scientific papers agrees. “I created the Dean’s President’s Annual Address to HSC Faculty, USC be a scientist, and that’s and 111 book chapters and Fifth-Year Scholar program President C. L. Max Nikias. Tuesday, Feb. 18 critical,” said Shaul Massry, has edited 32 books. He cre- to give students the oppor- Aresty Auditorium. RSVP: 10 a.m. Keck Hospital of USC MD, professor emeritus ated the Massry Foundation tunity to spend a full year (213) 740-1744 Guild Health Speaker Series and Luncheon. “Restoring of medicine, physiology in 1995. working on focused research Noon. Eli and Edythe Feeling to Fingers,” Milan and biophysics at the Keck According to Massry, projects to prepare them Broad Center for Stevanovic, USC. 10 a.m. School and president of the encouraging new scientists for further research after Regenerative Medicine coffee, 10:30 speaker, Massry Foundation. is vital to the future of medi- graduation and encourage luncheon at noon ($25). and Stem Cell Research The Foundation is best cine. “Clinical medicine is them in the development Seminar. “Regulation of Doheny Eye Institute, Third known for the prize in medi- critical,” he said. “It’s very of their academic medical Erythropoiesis by Long Floor Auditorium. Info: (323) Noncoding RNAs and mRNA- 254-0600, [email protected] cine that it offers to noted important to take care of careers,” he said. “We thank binding Proteins,” Wenqian scientists — 10 of the 31 patients. But to treat disease Dr. Massry for his founda- Hu, Whitehead Institute for Noon. Cancer Center Grand Massry Prize winners have and to find the right avenues tion’s generous contribution Rounds. Nikhil Wagle, Dana- Biomedical Research. Eli and gone on to win Nobel Prizes. for medications and therapy, to help our students meet Edythe Broad CIRM Center Farber Cancer Institute. Auditorium. Info: Aresty Auditorium. Info: Massry served as chief of we need to understand the those goals.” (323) 442-8084 [email protected] Wednesday, Feb. 12 Wednesday, Feb. 19 Etcetera 4 p.m. KSOM Dean’s 8 a.m. – 5 p.m. USC Diabetes Distinguished Lecture & Obesity Research Institute Paul Macklin, assistant ers. Fellows are awarded up To find out more, visit Series. “A Conversation Seminar. “From Cells to with Owen Bennett-Jones,” Psychology: Integrative professor of research, will to $95,000. The application www.tobaccoregulatory Owen Bennett-Jones, Insights into Diabetes and speak at the American Asso- is open through March 3. sciencefellowship.org/app. freelance journalist. Mayer Obesity,” various speakers. ciation for the Advancement Aresty Auditorium. Info: Auditorium. RSVP at www. of Science annual meeting, usc.edu/esvp (code: 21214). http://usc.edu/esvp (ESVP to be held Feb. 13-17 in USC Health Sciences Info: (323) 442-1900, code: dori2014) Public Relations and Marketing Non-Profit Organization [email protected] Chicago. As part of a discus- 1975 Zonal Ave. KAM 400 U.S. POSTAGE PAID University of Southern California Thursday, Feb. 20 sion on “big data” — data Los Angeles, CA 90033 Wednesday, Feb. 12 and Noon. Cellular Homeostasis sets so large and complex Feb. 19 Lecture Series. “NKT Cell that they become difficult Subsets in Inflammatory 8 a.m. – noon. Center for Diseases,” Vipin Kumar, to process using traditional Excellence in Research Two- Torrey Pines Institute. Info: applications — Macklin will Day Seminar. “Orientation to [email protected] Clinical Research at USC,” present his talk, “Integrating various speakers. Eli and Next-Generation Compu- Edythe Broad CIRM Center Friday, Feb. 21 tational Models of Cancer Auditorium. Info: research. 9 a.m. – 6 p.m. Saban Progression and Outcome.” usc.edu/for-investigators/ Research Institute Annual training Symposium. “Regenerative Medicine and Cellular The U.S. Food and Drug Thursday, Feb. 13 Therapies: Inventing the Administration (FDA) is Future for Children,” various Noon. Cellular Homeostasis offering mid-career profes- speakers, USC. Saban Lecture Series. “Post-trans- Research Building, First sionals the opportunity to lational Modifications of the Floor Auditorium, CHLA. spend a year in the Center FOXO3 Transcription Factor Info: [email protected], and the Pathogenesis of for Tobacco Products. chla.org/sabansymposium or Hepatitis C and Alcohol-re- FDA Tobacco Regulatory (323) 361-8715 lated Liver Disease,” Steven Science fellows help de- A. Weinman, University of velop science-based public Kansas Medical Center. Info: health strategies and serve as [email protected] the lead for defined projects, and meet with policy lead- Notice: Deadline for calendar submission is 4 p.m. Monday to be considered for that week’s issue—although three weeks’ advance notice of events is recommended. In case of an emergency... Please note that timely submission does not guarantee an item will be printed. Send calendar items to HSC Call the Emergency Information Phone: (213) 740-9233 The emergency telephone system can News, KAM 400 or fax to (323) 442-2832, or email to handle 1,400 simultaneous calls. It also has a backup system on the East Coast. [email protected]. Entries must include day, date, time, title of talk, first and last name of speaker, affiliation of Visit the USC Web: http://emergency.usc.edu This page will be activated in case of an emergen- speaker, location and a phone number for information. cy. Backup Web servers on the East Coast will function if the USC servers are incapacitated.