The Role of Fingernail and Tongue Analysis

The Role of Fingernail LUNULA and Tongue Analysis and Herbal Practice

PREVENTIVE METHODS DEVELOPED FROM OVER 10,000 PATIENTS‟ RECORDS November 18, 2012 – Mt. Pleasant, MI • 2010 Hardcover edition 2008 Edition Tsu-Tsair Chi, PhD TEETH MARKS • Over 120 color pictures

Tongue Color  1. Pink tongue Pink Tongue: Normal  COLOR  SHAPE 2. Pale tongue  VITALITY  COATING 3. Red tongue Light coating 4. Dark red/Purple on root of the  MOISTURE tongue

  Pale Tongue: Red Tongue:  Anemia Fever, Heart, Dark Red or Infection Purple Tongue: Blood stasis, Shiny areas on tongue: Anemia Spiky tongue: Serious Real fever

KIDNEY STOMACH LIVER  HEART ULCER  LIVER GALLBLADDER SPLEEN

STOMACH Elongated Cracks on (GI) LUNG Tongue tongue

  LUNG 

HEART Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Purple Dots: Blood Stasis SPIKY TONGUE Hypoglycemia Teeth Marks • Tip – Heart/Lung • Side – Liver/Gallbladder Lung • Center – Stomach/Intestine White Coating

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Roadmap-like Tongue

Younger People: Inflammation Tongue Ulcer Deficiency of Blood, FEVER Hormone and Chi Older People: Digestion, Lack of Spikes stomach acid

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 2 Tongue Movement vs. Diseases • Stiff tongue and movement not easy Whiplash – Stroke or cognition • Deviated tongue Heavy Metals – Whiplash, heavy metals, and stroke Stroke • Tongue shrinks and is difficult to stick out – Very serious condition Deviated • Unable to control tongue, slow movements Tongue and/or tongue hangs out: – Low IQ (since childhood) or stroke

Tongue Coating Distribution of Coating FEVER or • Root / No Root LOCAL • Light white: Normal INFLAMMATION: • Wet / Dry • White: Lung Stomach • Greasy / Not Greasy • Yellow: Stomach • Grow / Reduce Yellowish/White • Black: Digestion, Kidney, etc. Coating • Thick / Thin

Black Coating DIGESTION LIVER • High fever KIDNEY • Dehydrated • Chronic infection Black, Dry, Spiky Coating • Black/brown keratosis cell Black Coating • Digestion and Kidney

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 3 Mirror-Like Tongue • No coating GALLBLADDER KIDNEYS • Red color (thirsty, heavy chest, nauseous) – stomach and gallbladder condition STOMACH • Serum albumin low Green/Grey • Tongue cell metabolism retarded Red, dry, Coating – Digestion stopped • Electrolyte imbalance cracking tongue • Serious health condition

Mirror-Like Tongue (Slippery) Coating Location

SNOW-LIKE • Whole tongue: Stomach and Liver. COATING • Tip (outside): Stomach initiative. Low serum • Roots (inside): Stomach and Intestine albumin Autoimmune accumulation Disease, etc. • Left side: Inner Organs (difficult to treat) • Right side: Outside Organs (muscles) • No root: Stomach, kidney, spleen (serious)

Coating with Peeling Coating in No Root Coating Center

Serious Illness becomes Inner organs serious Condition problem

Sign of: Coating on • Heart problem Left Side SHAPE OR • Lung disease Dangerous • Cancer condition GROWTH • Parasites • Digestive CHANGE Caused by low oxygen levels in problem the blood

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. KOILONYCHIA (spoon nails) BEAU’S LINES Horizontal indentations across the nails PITTING

• Psoriasis • Chronic Dermatitis

Nail growth is • Alopecia interrupted by areata severe illness (hair loss) Anemia (heart attack) or Small malnutrition depressions

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. ONYCHOLYSIS TERRY’S NAILS (White nails) Opaque nails with a dark band on tip Nail separates from nail bed Psoriasis Injury Cancer Thyroid Congestive Heart failure disease COLOR Diabetes Fungal Liver disease disease CHANGE (cirrhosis) Drug Auto-immune reactions disease

5 MUEHRCKE’S LINES HALF and HALF NAILS Dark longitudinal streak(s) • Melanoma • Benign Kidney nevus Disease Renal Failure

RED AZURE LUNULA Cardiovascular Markers LUNULA Heart Disease Systemic Lupus Erymathosus (SLE)

Rheumatoid Silver poisoning, Wilson‟s disease, Nail Clubbing Ear Crease Arthritis quinachrine therapy Lung/Heart (> 50-60%) Heart (89%)

Cardiovascular Symptoms Red dots on tip of tongue Earlobe crease and cardiovascular risk Tip of tongue is red, ear crease, nail Heart Disease clubbing, lunulae on pinky Chronic circulatory problems allow the vascular Lack of lunulae, cold hands & feet, Poor Circulation numbness of the limbs (If the condition bed in the earlobe to collapse, causing the crease. improves, the lunulae should reappear) 1982 study: An earlobe crease plus chest pain, Atherosclerosis Vertical ridges etc. predicts a heart attack 89% of the time. Peripheral Artery Central nail canal (“fir tree” abnormality) Cardiac symptoms without an earlobe crease only Disease predicts 10% of heart attack cases. Stroke/Aneurysm Cherry angiomas on forehead 1991 study: patients with diagonal earlobe Protruding blue veins and/or red/black spots Heavy Metals underneath the tongue. Sometimes there is a creases had higher cardiac mortality rate and metallic taste. higher number of cardiac events. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 6 Nail Clubbing – Lung/Heart Nail Clubbing and Heart Disease Horizontal Ridges: Heart Condition Hemiplegia • Paralysis of half of body • Of 87 patients, 13.8% had clubbing on the affected side

Infective Endocarditis

• Inflammation of heart lining Lunula on the pinky Heart Condition • Of 60 patients, 50% had bilateral clubbing

Horizontal ridges Source: Journal of the American Academy of Dermatology. 2005; 52(6): 1020-28

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Peripheral Artery Disease Stroke/Aneurysm Salvia, Carthamus, Paeonia and Central Nail Canal Cherry Angiomas on Forehead Ligusticum Extracts on Cardiovascular Symptoms of 300 Patients • Cherry angiomas on forehead, Symptom 2 weeks 4 weeks 6 weeks 8 weeks • Family history of Headache 38.5 69.2 72.7 91.7 stroke/aneurysm, and Dizziness 40.0 65.0 --- 66.7 • Hypertension Cardiac Flutter 57.1 71.4 75.2 80.0 Cold Hands/Feet 12.5 37.5 --- 53.3 Risk is 23 = 8x higher Numb Hands/Feet 11.1 50.0 --- 55.5 than average people “Fir Tree” abnormality 1991. Japan Health Department. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Salvia, Carthamus, Paeonia, and Ligusticum Aging cells may lead to arterial damage Hippophae and Rhodiola Extracts Extracts on Cardiovascular Patients (30days) and plaque for Heart, Lungs, Energy 40 38.1 36.8 38.1 130 patients • Study from Washington University in St. Louis, MO 35 •  Mitochondrial efficacy to 28.9 • Mitochondrial function decreases in aging cells, utilize oxygen and glucose 30 26.6 allowing a reactive form of oxygen to leak for the production of energy 25 • Reactive oxygen causes damage to blood vessel walls (ATP) 20 • The body mounts an immune response to repair this • Repairs/Protects vascular 15 damage endothelial cells from free

thromblastrogram radical damage (vascular cell 10 • Immune cells attract a form of cholesterol that sticks to arterial walls, causing plaque and eventually damage contributes to 5

atherosclerosis cardiovascular disease) LD50 > 40 ml/kg

Fibrrinogen

Microcirculation

Index of Index

Red blood cell aggregation cellblood Red Blood viscosity Blood 0 Source: Nature. June 2005, Vol. 435 Reference: Townsend Letter. May 2011; 334. Journal of West China University of Medical Sciences. 1999;30:64. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 7 Hippophae and Rhodiola Extracts Hippophae and Rhodiola Extracts vs. CoQ10 ASPARAGUS EXTRACT CONTAINS: on Heart, Lung and Energy function

Action Extracts CoQ10 Action Extracts CoQ10 • ORGANIC FOLATE Increases energy within Improves mitochondrial (9 capsules or 3 bags contains > 400 g of organic folic acid) +++ +++ +++ 30 minutes efficiency Protects vascular Reduces lactic acid +++ +++ • ASPARAGINASE endothelial cells from +++ + Lowers lactate Trilinolein damage +++ +++ dehydrogenase (LDH) • ASPARAGOSIDE Active constituent of Hippophae Repairs and protect +++ Reduces malondialdehyde and Rhodiola Extracts DNA-damaged cells +++ ++ (MDA) • Eliminates shortness of GLUTATHIONE +++ breath Increases superoxide EPA dismutase (SOD), +++ +++ Relieves choking-like • VITAMIN B, C, E +++ glutathione (GSH) Eicosapentaenoic Acid (20:5) symptoms Anti-hypoxia +++ Reduces palpitations +++ • ORGANIC SELENIUM Reduces cholesterol +++ ++ DHA Minimizes chest +++ pounding Reduces triglycerides +++ + • ORGANIC ZINC Docosahexaenoic Acid (22:6) Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Xanthomas (eyelid plaque) may signal Asparagus Extract reduces Cardiovascular Wine Extract reduces cholesterol in Disease Risk by Reducing Homocysteine Levels Atherosclerosis, Ischemic Heart Disease, Myocardial Infarction, High Cholesterol* 155 patients (3 months) 40 90 35 39% 88% 80 84% 30 80% 70 25 28% 60 65% 20 % 50 15 40 10 • 48% higher chance of myocardial infarction 30 Folic Acid Homocysteine 5 (1 month) (4 months) • If present in those under 30 years old, 20

0 signals arterial plaque 10

Total Cholesterol Total Atherosclerosis Index Atherosclerosis • The American Journal of Clinical Nutrition. 2002; 76(4):758-65. 0 Triglycerides • JAMA. 2002; 288:973-979. *British Medical Journal. 2011; 343:d5497. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Heavy metal Blue veins under Heavy metal Silver and deposits the tongue deposit in gum Copper • Black- or blue-colored nails Poisoning • Dark, protruding veins under the tongue with red/black spots • Gum shows dark/blue lines • Metallic taste in mouth

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 8 Smilax, Sargassum, Rheum and Smilax, Sargassum, Rheum and Smilax, Sargassum, Rheum and Allium Allium Extracts Allium Extracts on Lead Toxicity Extracts vs. EDTA: Chelating Power 0.8

• Oral chelating herbal supplement /L) 0.7 0.725 110 Patients Pb2+ Cd2+ Hg2+ Zn2+

• No Side Effects 0.6 umole • Does not strip essential trace elements. ( 0.5 EDTA ++++ ++++ — ++++ • Safe for children (3 years and older) to take. 0.4 • Kidney patients can take with Asparagus 0.3 Extracts ++++ +++ +++ — Extract and use with Bathdetox 0.2 Lead in Urine in Lead 0.1 0.097 • Removes heavy metals through urination and 0 EDTA cannot recover liver damage caused by lead toxicity. 1st day 10 days fecal excretion The herbal extracts recover liver damage and do not inhibit • Inexpensive (10 days is one course, 3 courses is a treatment period) hemoglobin biosynthesis. Usage: 3-4 capsules, 3 times a day.

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Smilax, Sargassum, Rheum, and Allium Children with Lead Toxicity Smilax, Sargassum, Rheum and Allium Extracts on Lead Toxicity Extracts remove Mercury  Risk of ADHD 0.7 (68 children, ages 3-12) 0.556 0.3 0.6 • Loss of appetite 0.483

2 weeks mol/L) 0.5 0.428 50 cases • Hyperactivity μ 0.2 0.24 0.4 0.27

• Irregular sleeping habits g/mL 0.3 0.23  • Temper tantrums 0.1 0.12 0.2

• Lack of concentration in ( urine Mercury 0.1 0.0 0 Smilax, Sargassum, Rheum and Allium Extracts Day 0 Day 14 0 7 14 21 28 days chelate lead in children safely and . Zinc level increased from 4.58 to 4.87 g/ml Normal mercury in urine is < 0.250 μmol/L reduces/eliminates associated symptoms. . Associated symptoms reduced Metal Flush does not remove essential trace elements and has no side effects Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc.

Advantages of Smilax, Sargassum, Blue Veins under Tongue Your kidneys must be in good Earlobe crease with Red / Black Spots condition before undergoing Rheum and Allium Extracts intravenous chelation. When bubbles are present in the • Easy administration • Children (ages 3 and urine or edema is present in the legs, • Bubbles in the this indicates a kidney problem. Inexpensive above) can take urine • No side effects • Kidney patients can Protocol: • Does not strip take with Asparagus •Asparagus Extract Heart (89%) •Extracts of Rosa and Lygodium essential elements Extract and use with •Extracts of Smilax, Sargassum, Rheum Bathdetox Has a high chance for bypass surgery. and Allium Protocol: Extracts of Salvia, Carthamus, Paeonia and •Extracts of Eupatorium, Cinnamomum, Ligusticum + Asparagus Extract + Extracts of Smilax, and Atractylodes Sargassum, Rheum and Allium Leg Edema

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 9 ANEMIA Functions of Angelica, Cyperus, DEFICIENCY of BLOOD, Astragalus, Salvia Extracts HORMONE and • Improves anemia and malnutrition CHI – WBC, especially after Concave or Roadmap-like chemotherapy “spoon-like” Tongue in Younger – RBC,  Hemoglobin nails People •  Platelets (ITP) by 81%

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Angelica, Cyperus, Astragalus, Salvia Angelica, Cyperus, Astragalus and Salvia Extracts Extracts on 280 Women with Dysmenorrhea (3 months) Hormone Balance, Menopause, PMS 50 Recommended for pre- and postmenopausal women as well as men 48.21 Overall 40 Improvement . Balances estrogen, testosterone, progesterone 41.07 89% .  90% PMS PAIN 30 .  Irregular menstruation (75%) 20

.  Abnormal uterine bleeding (93%) Effective Rate Rate (%) Effective 10 .  Menopausal Syndrome (NHRT) 10.71 Red . Promotes fertility in both women and men 0 spots Effective Improved No Effect

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Angelica, Cyperus, Astragalus and Salvia Angelica, Cyperus, Astragalus and Salvia on Extracts on 60 Women with PMS (3 months) 120 Menopausal Women (3 months) Symptom % Reduced Symptom % Reduced 110 Overall Effectiveness: 96.67% 100 Hot Flash 87.37 Painful Intercourse 89.18 100 • In Women: Cysts, Fibroids, Endometriosis, 90 96.55 Fatigue 62.96 Palpitations 59.60 93.33 Fibrocystic breasts, Female organ cancer, etc. Headache 55.06 UTI 50.62 80 • In Men: BPH, Prostate Cancer, Testicle Irritability 43.01 Depression 32.26 70

Effective Rate Rate (%) Effective Cancer, etc. Joint Pain 29.61 Insomnia 23.72 60 • In Both Men and Women: Diabetes, Insulin Malaise 21.63 Dizziness 17.86 50 Resistance, Cardiovascular risk, Dementia, Heavy PMS Intermediate Light PMS Approximately 80% of women over 50 years old will Autoimmune conditions, Abdominal fat, etc. PMS benefit from the hormone-balancing effect of Chi-F 90 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 10 Hormonal Imbalance DIABETES HORMONES Physical Markers of Estrogen Dominance

WEIGHT CANCER • Red dots on the tongue MANAGEMENT ESTROGEN • Cherry angiomas on the abdomen • White spots on the nail White SEXUAL AUTOIMMUNE spots VITALITY CARDIOVASCULAR DISEASE • Facial Hyperpigmentation HEALTH

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Facial Hyperpigmentation: Cherry angiomas on the Forehead Cherry Angiomas on Abdomen Estrogen dominance • If > 10 to 15 large ones – Men: Prostate Cancer risk – Women: Breast Cancer risk – Or Liver Cirrhosis in both men and women

Chloasma, Melasma

94 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Cyperus, Curcuma and Extracts of Cyperus, Curcuma, Astragalus Extracts of Cyperus, Curcuma and MECHANISM Astragalus reduces Estradiol Astragalus Extracts Aldosterone EXTRACTS/ Postmenopausal Women with Fibroids/Cysts DIM Corticosterone 11- Cortisol Cortisone 80 • Aromatase inhibitor for women and men Deoxycortisol Aromatase 16-OH 60 patients estrone ( Estradiol,  Estrone, Testosterone) Estrone 60 74.52 Proges- 17-OH 2-OH • Competes with estradiol at estrogen terone Progesterone estrone EXTRACTS 40 receptors 17-OH Androste- Testos- 38.84 Pregnenolone Estradiol Pregne- DHEA nedione terone 17-OH 20 nolone estrone •  Belly Fat 5- reductase Aromatase • Also for Type II Diabetes patients (with DHT 0 Cholesterol Before 10 Days After 16-OH 16-OH dehydroepi- Estriol Diabend and OxyPower androsterone androsterone Postmenopausal women: Estradiol level < 35 pg/ml

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 11 Extracts of Cyperus, Curcuma and Astragalus Comparison of grayscale values of Extracts of Cyperus, Curcuma and inhibit aromatase expression in ovarian and aromatase expression in rat endometrial Astragalus: Aromatase Reducer endometrial tissue in rats and ovarian tissues

Ectopic Ovary • Recommended for pre- and Ectopic Group endometrium endometrium (mean + SD) postmenopausal women tissue (mean + SD) • Recommended for men Negative control 48.0 + 8.5 29.7 + 6.4 • Multiple applications for estrogen- Positive control 108.9 + 29.03 149.8 + 33.86 Ovarian dominant and hyperaromatization tissue Herbal extracts group 34.7 + 5.2 47.0 + 9.19 conditions (28 days) Negative Control Positive Control Extracts group after Aromatase reduction No stains Tremendous aromatase 28 days 100% 85.6% expression Aromatase (Herbal extracts) expression inhibited Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. AROMATASE INHIBITORS Extracts of Cyperus, Curcuma and Extracts of Cyperus, Curcuma, Astragalus + Astragalus on 255 Patients with Ovarian Extracts of Bolbostemma + Sea cucumber Product Manufacturer Indication on 60 patients with Uterine Fibroids Administration, Cost Approval Date Cysts and Endometriosis ARIMIDEX AstraZeneca Breast cancer in 60 70 postmenopausal women 57.6 69.2 Oral, $220/month 12/27/1995 50 ~ 5 months 60 6 months AROMASIN Pharmacia Advanced breast cancer in 50 40 Oral, $224/month 10/21/1999 postmenopausal women after 40 tamoxifen therapy % 30 34.1 % 30 FEMARA Novartis Advanced or metastatic breast 20 20 Oral, $225/month 1/10/2001 cancer in postmenopausal 10 19.0 women 8.2 10 0 11.8 Extracts of Cyperus, Dietary Estrogen-related conditions Effective Improvement No Change 0 Curcuma, Astragalus Supplement (cysts, fibroids, ovarian/breast/ Effective Improved No Change prostate cancer, etc) in men 1994 study from Chang Hai Hospital in Shanghai, China Oral, $45-$90/month *Those with uterine fibroids over 5cm should add and women. Overall Improvement Rate of 92% within a 5-month period. No side effects Revivin and Angiostop for better results. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Cyperus, Curcuma and Astragalus on 100 Patients with Factors influencing risk of I. Long-term Hormone Stimulation Fibrocystic Breasts Breast/Ovarian Cysts/Cancer in women 60 60 Breast Abnormalities 50 6 months 40 I. Long-term Hormone Stimulation • 40% women of childbearing age already % 30 – Among women with fibrocystic breasts for develop fibrocystic breasts 30 20 over 20 years, 17% developed breast cancer • 42%: First time breast cancer diagnosis at 65 10 10 II. Obesity/Belly Fat years old 0 Effective Improved No Change III. Xenoestrogens • 1 in 6 American women who reach 80 years • 90% improved in 6 months IV. Hyperaromatization old develop breast cancer • 94% of the pain associated with cystic fibrosis had disappeared

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 12 Dense Breast Tissue: Risk for Breast Cancer • More than half of all women have dense breast tissue Progesterone HRT Increases Breast Cancer Risk • Risk for breast cancer is 5x greater in women with dense breast tissue • Listed as “Carcinogenic” under California‟s • England Study: If Estrogen + Progesterone are used • Senate Bill 791 (CA) – effective 4/1/2012 Prop 65 since 1988 together  Requires that patients be informed of their breast • A listed substance may be natural, synthetic or – 66% increase in breast cancer incidence cancer risk if dense breast tissue is found in even naturally produced in the body – ~15,000 more cases per year mammogram • Progesterone products should have a warning • If only progesterone is used Breast Calcification: Precancer label – 22% increase in breast cancer incidence • Small clusters of breast calcification is an early warning Source: NNFA Today. Sep 2004; 18(9) • Total of 20,000 more breast cancer cases every year sign of breast cancer

• Should be treated immediately Even bio-identical hormones may pose a risk Source: Family Physician. Sep 2003. Sources: Int J Bioinform Res Appl. 2010;6(4):418-34; Br J Cancer. 2010 Sep 8;103(7):1034-1039. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc.

II. Obesity and Cancer Extracts of Cyperus, Curcuma and III. Xenoestrogens Astragalus for Belly Fat (Environmental Hormones) Obese persons have high estradiol, • Substances that mimic the low testosterone levels Aromatase converts testosterone into estrogen. More estrogen means more fat accumulation, effects of estrogen • Breast cancer • Prostate Cancer especially in the belly, which has the highest • Attach to estrogen amount of aromatase. The herbal extracts reduce receptors and disrupt – Larger tumor size – More aggressive endocrine functions – Advanced grade tumors aromatase and consequently reduces belly fat. • Common xenoestrogens: – Increased nodal – Higher recurrence For weight loss, take with clouding agents, pesticides, Underdeveloped white seeds involvement rate Extracts of Raphanus, Crataegus, Alisma, in watermelons signify phthalates in plastics, dyes presence of xenoestrogens – Higher mortality Garcinia, Paeonia and Tyrosine .

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Plasticizers: Xenoestrogens Effect of Xenoestrogens on Men Extracts of Cyperus, Curcuma and DEHP, DINP, BBP, DBP • Reduces sperm count – Only ~46 million/ml for men around 20 years old Astragalus counteract the effects of • Plasticizers as clouding agents (Avg 84 million/ml for men 30-50 years old) xenoestrogens by competing with found in sports drinks, juices, – 1940s: avg was 60 million/ml. Now avg is 20 million/ml estrogen and binding to estrogen tea drinks, fruit jams or syrups, • Lowers ejaculation receptors and tablets or powders • Doubles testicular cancer risk • Causes cancer and damage to the reproductive – rate has doubled in the last 40 years Hugo Rodier, MD, from Utah system, heart, kidneys and liver • Increases male breast cancer recommends the herbal extracts for his • Men: Has feminizing qualities, reduces sperm – 1973: 86 per 100,000 were twice at risk patients who are exposed to • Women: Early puberty,  breast cancer risk – 1998: risk increased 1.08 times – 2004: 1,600 cases of breast cancer diagnosed xenoestrogens Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 13 IV. Hyperaromatization of Testosterone People at risk for Hyperaromatization have the following conditions: Symptoms of Hyperaromatization (High estradiol, Lower Testosterone) Pregnenolone Cholesterol (High estradiol, Lower Testosterone) Aromatase

Estrone (E1) –Overweight Progesterone – Overweight (or difficult to lose weight) – Type 2 Diabetes –Low libido • Insulin Resistance  Hypertension DHEA Androste- Testosterone Estradiol (E2) –Reduced muscle tone nedione •  Cholesterol   Triglyceride –Gynecomastia Aromatase • Family history of Diabetes Estriol (E3) Source: Jonathan Wright, MD. “Bio-Identical Hormone Replacement Therapy: Common Issues and Solutions.” Townsend Letter. Jan 2010. Extracts of Cyperus, Source: Jonathan Wright, MD. “Bio-Identical Hormone Replacement Therapy: Curcuma, Astragalus Common Issues and Solutions.” Townsend Letter. Jan 2010.

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Any type of Hormone Therapy Suzanne Somers‟ Interview with Increases Breast Cancer Risk When on Hormone Replacement Dr. Jonathan Wright Estrogen + Progesterone Study Therapy, including Bio-identical In any situation, make sure Years of use Risk hormones, and birth control pills, E3 > E1 + E2 10 – 15 88% higher than non-users add Extracts of Cyperus, 15 – 20 Double than those using for 10-15 years “Women were more likely to be long-term breast Curcuma and Astragalus to avoid cancer survivors...if they had more estriol (E3) Risk keeps increasing with longer durations of than estrone (E1) and estradiol (E2)” use and never tapers off hormone-related side effects Source: Townsend Letter. Aug/Sep 2010: 54-56. Source: American Association for Cancer Research. April 1, 2012.

122 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc.

Jonathan Wright, MD  Townsend Letter (Jan 2010) Estrogen and the Prostate Cherry Angiomas on Abdomen: Prostate Problems • Estrogen Quotient (EQ) • 2/16 Hydroxyestrogen Ratio – EQ > 1: preponderance of – 2/16 ratio < 2 is related to estriol, lower estrogen- cancer risk in men, pre- and related cancer risk postmenopausal women on – EQ = E3 / (E1 + E2) BHRT • E3 > (E1 + E2)

Pregnenolone Cholesterol

2-OH Progesterone Aromatase estrone Estrone (E1) 16-OH estrone

DIM DHEA Androste- Testosterone Estradiol (E2) nedione Aromatase I3C

Estriol (E3) Extracts of Cyperus, Red Dots on the Tongue: Prostate Problems Curcuma, Astragalus

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 14 Extracts of Melia, Citrus, Phellodendron, Salvia Extracts of Melia, Citrus, + Extracts of Cyperus, Curcuma and Astragalus Causes of Abnormal Increase of Phellodendron and Salvia for Prostate Problems

Pregnenolone Cholesterol Estradiol Levels in Men . Benign Prostatic Aromatase Benign Estrone Hyperplasia (BPH) Prostatic Progesterone

• Hyperaromatization of testosterone Hyperplasia Androste- Testos- . Prostatitis DHEA terone Estradiol (BPH) nedione Aromatase • Impaired liver function 5- . Hair Loss in men Prostatitis reductase • Obesity – increases aromatase expression DHT Hair Loss in Add Extracts of Cyperus, Curcuma and Estriol men Extracts of Cyperus, Extracts of Melia, Citrus, Astragalus for best effects for men Curcuma, Astragalus Phellodendron, Salvia

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Normal Testosterone Level Biopsy recommended for men Disadvantages of Biopsies with PSA > 2.5 • Decreased depression • Definite risk of spreading the cancer • Improved memory • 82% missed cases without biopsy: • Painful and uncomfortable procedure • Adequate levels of DHT correlated with:  men < 60 years old Instead watch for these physical signs – Improved sexual function indicating high estrogen and possibly a high – Less aggressive prostate cancer risk • 65% missed cases without biopsy: PSA level: Source: Jonathan Wright, MD. BHRT Symposium. June 25, 2011.  men > 60 years old  Red dots on the root of the tongue To normalize Testosterone Level, take Extracts of Sources: Patient Care. December 2003.  Cherry angiomas on the abdominal area Cyperus, Curcuma and Astragalus with Extracts of New England Journal of Medicine. 2004; 350(22):2239-46. Melia, Citrus, Phellodendron, Salvia

130 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Ovarian Cysts, Ovarian Cancer Odds Ratio in the US FUNCTIONS • 1:500 women develop ovarian cysts within 5 years Extracts of Cyperus, Curcuma, Astragalus after menopause • Fibrocystic breast  Colon polyps Estrogen related to • 0.2% develop into ovarian cancer • Endometriosis  Cervical cancer • Ovarian cyst/PCOS  Breast cancer Diabetes and Breast Cancer Odds Ratio in the US • Uterine fibroid  Ovarian cancer • 1:22 women 50 years ago • Thyroid cyst  Uterine cancer Insulin Resistance • 1:6 women over 80 years old (year 2000) • Kidney cyst  Prostate cancer • Among newborn girls in 2010, 1:3 will get breast • Liver cyst  Testicle cancer . Extracts of Gymnema, Morus, Coptis, Astragalus cancer within their lifetime • Neurofibromatosis  Lung cancer . Extracts of Hippophae, Rhodiola Prostate Cancer Odds Ratio in the US • Type II Diabetes  Reduces belly fat . Extracts of Cyperus, Curcuma, Astragalus • Acne  Competes with xenoestrogens, • 1:6 men reducing their effects Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 15 Insulin Resistance, Diabetes, PCOS Hypoglycemia Extracts of Gymnema, Morus, Dark, wrinkly Coptis, Astragalus Functions • Tongue is red and has pigmentation teeth marks Acanthosis nigricans •  Blood glucose • Since hypoglycemia is a •  Glucose tolerance precursor to Diabetes, and Children: Fatty liver vice versa, it is important •  Insulin receptor sensitivity to regulate blood glucose •  Beta cells of pancreas to produce levels Teeth marks Skin tags 80% Type 2 Diabetes risk more insulin Those who have high iron levels in the blood are May also be a colon problem • Antioxidant not only likely to develop cancer but are 3 times more likely to develop diabetes. 50% chance colon polyps • Regulates lipoprotein metabolism

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Insulin Resistance Extracts of Gymnema, Morus, Dangers of Excess Estrogen in Aging Males • Present in at least 1 in 3 • Signs and Symptoms Coptis, Astragalus men with below-median . Sugar or carbohydrate • Double the stroke risk for Type II Diabetes (6 months) serum testosterone craving •  Heart Attack, Myocardial infarction risk • Associated with . Shaky without food • Atherosclerosis chance hyperaromatization and . Obesity, especially belly fat estrogen excess • Thrombus (blood clot) incidence Effective . Skin tags Group Total Cases Effective Rate • If low or below-median •  Prostate cancer, BPH risk Cases o 80% risk of Type 2 testosterone Diabetes Sources: Diabend 195 133 68.2% (hyperaromatization, . Osteoarthritis Int J Cancer. 2006; 118(9):2123-31 Annals of the NY Acad Sci. 2006; 1089: 77-193 Control 30 2 7.0% test for insulin o ~80% have Minerva Endocrinol. 2006; 31(1):1-12 resistance! metabolic syndrome J Cell Biochem. 2007; 102(4):899-911 Reprod Toxicol. 2007; 23(3): 374-82 Source: Jonathan Wright, MD. “Testosterone Evaluation, Treatment, Safety.” BHRT FASEB J. 2007 Nov 30 [Epub]. Symposium. Las Vegas, NV. June 24, 2011. Basic Clin Pharmacol Toxicol. 2008 Feb; 102(2):134-8 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Estrogen and Cardiovascular Disease STOMACH • Crack(s) on tongue ULCER Cherry • Black line(s) on nails Angiomas on Forehead • Yellow coating on tongue Cracks on • Roadmap-like tongue tongue Stroke or • Geographic tongue (IBS, Aneurysm Crohn‟s disease)

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 16 Stomach or Esophageal Problem Roadmap-like Tongue Yellow Auricle cyst Coating Older People: If GERD is Digestion, Lack of Digestive present stomach acid problems 22 = 4x chance

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Black lines on the fingernails and a Case Study: R.S., 67 y/o/m, esophageal and stomach issues Extracts of Paeonia, crack on the center of the tongue Atractylodes, Poria often indicate stomach bleeding. (For teeth marks & crack in center of tongue) Digestive Enzymes The stool will not often Pale and show if you have minor shiny Absorption bleeding. Stomach bleeding tongue H. Pylori bacteria is caused by acid and pepsin secretion. If you Adjusts stomach/intestinal muscle have this condition, contractions digestive enzymes should Balances stomach acid not be used. Repairs stomach/intestine membrane Deep crack Yellow coating Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Paeonia, Atractylodes and Extracts of Paeonia, Atractylodes and DigestronPoria on on Digestive Digestive Problems Problems Poria for Digestive Disorders 39-year-old male with Rate (%) Stomach Cancer Condition 30% Stomach Cancer 60% Effective Improved 59.0% 952 cases is Stage IV 50% Gastritis 65.7 28.6 16% metastasized 40% Chronic Atrophic Gastritis 47.7 17.4 stomach cancer is 30% Gastric Ulcer 79.7 17.0 HER2 + 29.1% Duodenal Ulcer 69.5 28.8 20% Need Angiostop Irritable Bowel Syndrome* 50.5 39.8 10% 11.9% (EGFR inhibitor) Diverticulitis/Colitis* 40.3 18.2 0% – 35% prolongs life Effective Improved No Effect *GI Chi + Psoricaid + Digestron for IBS and Diverticulitis/Colitis For GERD, take Digestron + Debile

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 17 Cancer patients: Tongue has greasy coating Markers/Symptoms of Liver Problems • Dark, branching veins • Spider veins on the under the tongue chest and abdomen • Red or dark spots on the • Dark or red bands on sides of the tongue the tips of the nails (blood stasis spots) • Red palm • Thick and wide tongue • Bloating, dry mouth, • Large cherry angiomas bitter taste, fatigue on the chest and • “Panda eye” (dark abdominal area circle around eye) Stomach Cancer

Dark, branching veins under the tongue Characteristic of Veins under the Tongue and Liver Conditions 4 or more veins

Liver condition (N) 2 veins >2 veins Thickness Width Length under the tongue

Hepatitis (60) 90% 10% 5.21+0.31 3.34+0.21 5.45+0.30 • Liver cirrhosis Liver Cirrhosis (50) 26% 74% 3.08+0.27 3.78+0.30 5.62+0.1

Liver Cancer (40) 45% 55% 3.10+0.4 4.34+0.21 5.63+0.1 • Liver cancer Fatty Liver (60) n/a n/a 3.18+0.27 3.34+0.31 5.71+0.42

Alcohol-induced Fatty Liver: SGOT (AST) level is two times higher than SGPT (ALT) level. Both levels are moderate-high.

Cherry Angioma Cherry angiomas and spider veins . An indication that estrogen attacks Cherry Angiomas on Abdomen peripheral blood vessels, causing an aneurysm • If > 10 to 15 large ones . Metabolism of too much estrogen causes liver problems –Men: Prostate Cancer risk –Women: Breast Cancer risk –Or Liver condition in both men and women

162 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 18 Yellow skin (Jaundice) Red Palm and Hot Spider Veins/Skin itching

Liver Cirrhosis Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Schisandra, In vitro study (2002): Bupleurum, Smilax Hepatitis A and B, Fatty Liver Studies Extracts of Schisandra, Bupleurum, Fatty Liver, Hepatitis, Liver Cirrhosis • Hepatitis A and B patients: ALT Smilax on Hepatitis C (SGPT) levels in 47 cases by 73% in • The herbal extracts have been  AST (SGOT)  ALT (SGPT) 3 months  HEPATITIS VIRUS TITER proven to inhibit Hepatitis C • Fatty Liver: 100% effective in 7 RNA virus replication and  JAUNDICE  BITTER TASTE cases expression in 6 days The herbal extracts stop Hepatitis C RNA • Excellent for bloating, bitter and dry virus replication and expression in 6 days mouth, cherry angiomas, fatigue • The herbal extracts do not have a toxic effect on normal liver cells LD50: 12.50 g/kg

167 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Frenula Cyst (Lower) Frenula Cyst (Upper)

Colon/rectum condition Intestine/upper colon condition

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 19 Multiple Frenula Cysts 3 Factors of Colon Polyps

Factor Recommendation  Bowel Amorphophallus, Angelica, Lycii Extracts irregularity  Excess bile Schisandra, Smilax, Bupleurum Extracts from liver Mentha and Curculigo Extracts  Excess Cyperus, Curcuma, Astragalus Extracts estrogen Symptoms suggest estrogen affects liver and colon Those without gallbladder → high chance of Serious condition colon cancer

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Amorphophallus, Internal Bleeding Inflammatory Bowel Disease related to Angelica, Lycii Autoimmune Disorders

• Colon, Intestine Detoxifier Studies show that the incidence of autoimmune • Regular Bowel Movements problems in people with Crohn‟s disease and • Balances pH of intestines and Ulcerative Colitis is greater than those without promotes good bacterial these diseases. growth Dark • Cholesterol, Weight Control line(s) For best results, take Extracts of Paeonia, • Blood Glucose Regulation on nails Atractylodes, Poria with • Healthier, Blemish-Free Skin Extracts of Euphorbia, Sanguisorba, Phellodendron LD50: 45 g/kg for Crohn‟s disease and Ulcerative Colitis

Geographic Extracts of Euphorbia, Tongue Phellodendron and Sanguisorba • IBS Colitis, IBS, Diverticulitis • Crohn‟s disease For gastrointestinal infections, • Lung Use immediately • Sinus/allergy

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 20 KIDNEY PROBLEM -Black Tongue Horizontal white line(s) across the fingernail Kidney problem Horizontal white line

30-year-old Male with Proteinuria

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Proteinuria IgA Nephritis Signs of Kidney Problems • Puffy face when waking up • Foamy urine • Teeth marks on tongue • Edema in legs/ankles • Dark color/puffy under eyes • Half-and-half nails • Horizontal white line or strips on nails • Yellow or black coating on root of tongue Half-and-Half nails

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Foamy urine Teeth Marks Serious Leg Edema KIDNEY PROGRAM • Asparagus Extract •  Creatinine, Diuretic • Cordyceps Extract •  BUN • Extracts of Rosa, Lygodium, Smilax, Centella • Proteinuria • Extracts of Eupatorium, Cinnamomum, Atractylodes •  Edema,  BUN,  Ereatinine,  Skin Proteinuria Itching Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 21 Cordyceps Extract on Kidney ASPARAGUS EXTRACT Function of 349 Patients Extracts of Rosa, Lygodium, 25 Smilax, Centella 24.37 Before 20 After • Diuretic Agent  Urinary Tract Infection  Kidney Stones 15 15.26 13.5 •  Creatinine levels 10 12.4  Frequent Urination  Prostate

•  Renal glomerulus re-absorption 5 5.2  Difficulty urinating  Gout 3.5 2.89 3.14 0 •  Kidney function BUN Creatinine Hemoglobulin RBC (mg/dl) (mg/dl) (g/dl) (m/mm3) Toxicity Study: 480 times of the regular dose, in mice shows no toxicity Overall 85.9% improvement

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. In vivo Antibacterial Study: Extracts of Rosa, Lygodium, Smilax and Extracts of Rosa, Lygodium, Smilax, and Extracts of Rosa, Lygodium, Smilax, Centella Centella on Genitourinary Conditions Centella on 6,512 cases of Genitourinary Conditions vs. Cephalexin 70 Condition N Effective Rate Number of rat survivors 60 64.34% Rat Dose 6,512 cases -1 -1 Staphylococcus E. Bacillus Streptococcus (3,880) Frequent urination 172 82.71% # kg /d 50 aureus Coli pycyaneus pyogenes Type I Acute cystitis 984 71.95% 40 Saline 20 20ml x 7 2 1 1 2 Vaginitis (Trichomoniasis and Candidiasis) 243 65.84% 30 Kidney stones 221 62.44% Cephalexin 20 1mg x 7 14 13 12 14 20 Proteinuria 19.78% Urine protein > 3.58 g/L for 2 weeks 478 59.41% Kidney Chi 20 54mg x 7 12 11 7 10 10 (1,288) 15.88% Serum albumin < 3.0 g/L, Edema (1,034) Kidney Chi 20 18mg x 7 10 10 7 7 0 UTI 1057 42.48% Effective Improved No Change Prostatis 288 21.53% Kidney Chi 20 6mg x 7 7 5 5 5 Source: JTCM. 2003; 44(4):311. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Skin Dialysis Mechanism

Those who have Extracts of Eupatorium, Na-,K-,Cl- Sweat Medium-sized Biowastes***

frequent bladder infections Cinnamomum, Atractylodes Urea Increase Urea Excretion BUN should take Electrolyte Water KIN IALYSIS ORMULA Balance S D F Cyanate Excretion Monoaminoxidase Kidney Asparagus Extract with Extracts of Medulla Detoxifies through the skin without hurting the Poison Osmosis Edema Rosa, Lygodium, Smilax, Centella kidneys and liver Norepinephrine Body Balance Urine for excellent results Reabsorption The herbal extracts can remove these biowastes Kidney Lung Norepi- Circulation Great to have when traveling and also through the skin: urea, creatinine, uric Acid, cAMP, Function nephrine purine compounds, aromatic compounds, to prevent sexual disease. Angiotensin I Angiotensin II Urine polyamines, indoles, phenols, myoinositol, sorbitol, ***One of the causes of fibromyalgia is the Make it part of your first aid regimen. oxalic acid, etc. accumulation of biowastes. These biowastes Ketone & Anti-Diuretic can be removed through the blood (use Vein Hormones Lite) or through skin dialysis using Bathdetox. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 22 Extracts of Eupatorium, Case study: 36 y/o/m with Focal segmental INFECTIONS Cinnamomum, Atractylodes glomerulosclerosis (Autoimmune disease) 90  For bladder/vaginal area infection 80 87% Half and half Nails 83% – Extracts of Rosa, Lygodium, Smilax, 70 77% Centella 60 50  For upper respiratory 40 41%

Improvement Improvement 30 (throat/esophagus) area infection 20 26% – Bamboo Extract 10 0 BUN Creatinine Proteinuria Edema/ Pain/  For gastrointestinal infection Skin Itching Fibromyalgia – Sanguisorba, Phellodendron, Euphorbia

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Lyme Disease Lyme Disease Symptoms Lyme Disease Protocol • Caused by tick-borne bacteria Recommendation For infection in the… Borrelia burgdorferi • Categories • Regular treatment is through – Skin  Musculoskeletal antibiotics – Respiratory  Gastrointestinal Bamboo Extract Respiratory system Deer tick Extracts of Rosa, Erythema • Skin itches on the bitten area migrans • Nearby joint pain, then limb numbness Lygodium, Smilax, Urinary system Circular/spiral and blurred vision Centella skin rash • Then the infection goes to the blood and Extracts of Eupatorium, associated with Rash becomes the nervous system Cinnamomum, To remove toxins Lyme disease bigger Atractylodes

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Markers of Lung Bilateral Nail clubbing and Lung Diseases NAIL Pulmonary Diseases Total cases Cases w/ clubbing % Problems Cystic Fibrosis 73 73 100 Cirrhosis CLUBBING 14 9 64.3 • Nail Clubbing (Hepatopulmonary syndrome) Hypersensitivity pneumonitis 82 44 53.7 • Geographic tongue Interstitial Pulmonary Fibrosis 588 289 49.2 Asbestosis 167 72 43.1 • Vertical ridges on opaque nail Mesothelioma 77 23 29.9 • White coating on tongue Bronchogenic carcinoma 111 32 28.9 Pulmonary arteriovenous malformation 93 18 19.4 • Tongue inflamed around the edges Sarcoidosis 90 11 12.2 Tuberculosis 426 72 16.9

Source: J American Academy of Dermatology. June 2005; 52(6): 1020-28 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 23 Geographic Tongue White Coating Vertical ridges on opaque nails

Sinus allergy, Lung Problem

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Anti-Hypoxia Effect: Herbal Extracts vs. Tongue inflamed around edges Extracts of Hippophae and Rhodiola Rhodiola alone in mice for the Lungs 32 • Lung congestion 30.6 (as quickly as 20 mins) 28 • Anti-Hypoxia 26.4 • Energy, Anti-Fatigue 24

•  Throat clearing (mins) time Survival 23.4

•  Pulmonary and Brain edema 20 Control 0.125 g/kg 0.125 ml/kg Rhodiola Extracts

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. BAMBOO EXTRACT Bamboo Extract + Cephalexin more effective than Cephalexin alone Bamboo Extract for Oral Candida  Acute and chronic throat and lung • People with low immunity such as diabetes Effective Duration of Effective conditions Age Rate disease Rate patients, children, the elderly, HIV patients, long- LD > 20g/kg  Cough with phlegm 50 < 40 years old 100% > 10 years 81.94% term steroid users, and cancer patients - More  Sore throat 41-60 years old 81.2% < 10 years 78.1% prone to candida in the mouth and throat > 60 years old 32.8% • Antibiotics and/or pain medication are often  Runny nose  Asthma unnecessary. *Cephalexin alone is only 6.1% effective  Ear irritation in Children • Instead they should take Bamboo Extract for Overall, Bamboo Extract + Cephalexin is 81.2% effective candida. FIRST AID for upper respiratory conditions for all age groups and duration of disease

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 24 Extracts of Astragalus, Extracts of Astragalus, Xanthium, BRONCHITIS PNEUMONIA Saposhnikovia on Allergic Rhinitis Xanthium, Saposhnikovia

50 57.2 367 cases • ALLERGIC RHINITIS 40 % 30 • SINUSITIS 20 22.9 19.9 10 Take before the allergy season starts 0 Effective Improved No Change

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Only thumbs have lunulae EMPHYSEMA CANCER • Only thumbs have lunulae (80%) • Physical signs Especially if 8 lunulae were present and then disappear  feel cold

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Physical Signs to Determine Early Physical Signs to Determine Early Physical Signs to Determine Early Signs of Cancer Signs of Cancer Signs of Cancer

TYPE OF TYPE OF SYMPTOMS SYMPTOMS TYPE OF CANCER SYMPTOMS CANCER CANCER Kidney Cancer Urinary bleeding with no pain • Frenula cyst Breast and • Red dots on tongue Colorectal • Shape of stool changes, sometimes with blood Prostate • Lots of cherry angiomas (>10 to 15) on • Nail clubbing with chronic dry cough Cancer • Soft, light-colored hair on the cheeks on adults Cancer chest, may also be Liver Cancer Lung Cancer • Soft, light-colored hair on the cheeks on adults Cervical Stomach If the digestive symptoms suddenly change with Vaginal bleeding after intercourse Lymphoma, • Triangular nails Cancer Cancer severe pain Leukemia • Nail clubbing Ovarian/ Sudden vaginal bleeding in postmenopausal Ear ringing on one side only (For brain Esophageal GERD patients who feel like food is stuck in the Uterine Nasopharyngeal women cancer: also headaches and blurred Cancer throat or it goes down very slowly Cancer Brain Cancer vision) Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 25 Sea cucumber Extract can inhibit all 4 RTKs and Stomach Esophagus/Stomach Associated Cancer Processes Not every RTK drug can target several VEGFR PDGFR EGFR (Avastin, Nexavar, (Gleevec, Nexavar, (Tarceva, Erbitux, FGFR Sutent, Votrient, Sprycel, Sutent, Herceptin, Iressa, (Votrient) cancer processes simultaneously Zactima) Votrient) Tykerb, Zactima) 1 2 Angiogenesis    3 • Angiogenesis Proliferation    • Invasion Apoptosis   Lymphomagenesis  • Metastasis Tumor Vascular  • Proliferation Maturation Mitogenesis   Lump, thickening or wrinkle • Inhibition of apoptosis Hard lump about 2 inches on the auricle Cellular motility   above or to the left of the navel Metastasis   Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Sea Cucumber Extract Mechanism Sea Cucumber Extract inhibits 4 RTKs, associated cancer types VEGFR PDGFR EGFR FGFR Sea Cucumber Type of Cancer (Avastin, Nexavar, Sutent, (Gleevec, Nexavar, (Tarceva, Erbitux, (Votrient) Inhibition of growth factor signaling Votrient, Zactima) Sprycel, Sutent, Votrient) Herceptin, Iressa,  Tykerb, Zactima) Bladder     Extract EGFR, PDGFR, VEGFR, FGFR Bone     Inhibition of signal Induction of transduction pathway Brain (Glioma)   apoptosis Neo-Angiogenesis and RTK intermediates Breast    AKT / Colorectal   RAS Inhibitor Nuclear Esophageal    membrane Gastric     Inhibition of DNA’s Head and Neck    LD50 = 4.3g/kg orally in mice  Topoisomerase2 Kidney    Leukemia  

Cell Liver    membrane Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Sea Cucumber Extract inhibits 4 RTKs, associated cancer types Sea Cucumber Extract inhibits angiogenesis Cancer recurrence rate increases after surgery VEGFR PDGFR EGFR FGFR Type of Cancer (Avastin, Nexavar, Sutent, (Gleevec, Nexavar, (Tarceva, Erbitux, (Votrient) Breast Cancer Colon and Lung Cancer Votrient, Zactima) Sprycel, Sutent, Votrient) Herceptin, Iressa, as illustrated by thermal imaging Tykerb, Zactima) Study : 1,173 breast cancer patients Lung and colon cancer surgery linked Lung     treated with surgery, 520 had relapse to cancer recurrence. (20% of premenopausal women relapsed Lymphoma   within 10 months after surgery). Colon cancer patients who had surgery had higher relapse rate than invasive Melanoma   Source: Intl J Surgery. 2005. laparoscopy Meningioma   Source: Lancet. 2002. Myeloma   4/11/2005 6/28/2005 8/24/2005 Nasopharyngeal   Chance of recurrence and metastasis after surgery: • Within 2 years – 50% Ovarian    Between 4/11/05 and 6/28/05, this 42-year-old female patient took no herbs and had a positive mammogram and ultrasound. Beginning 6/28/05, patient took Sea Cucumber • After 5 years – 5% Pancreatic     Extract and results have been remarkable. It appears angiogenesis has receded, which is Recommendation: Use an angiogenesis inhibitor like Angiostop the best possible outcome. Prostate     - Medi-Therm Imaging before and after surgery to help minimize recurrence Thyroid   Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 26 Sea Cucumber Extract TARGETS FOR ANTI-CANCER AGENTS Bolbostemma/Fritillaria Extract Inhibition of growth factor signaling Inhibits G1-S transition in Cell Cycle • Multiple RTK targets (VEGFR, EGFR, PDGFR, Sea Cucumber Ext A disruption in the cell cycle can cause the cell to multiply FGFR): more effective Bolbostemma Ext EGFR, PDGFR, VEGFR, FGFR uncontrollably, forming a tumor. • Also Topoisomerase2 inhibitor Induction of Inhibition of signal apoptosis transduction pathway • Used before and after surgery and biopsy to reduce intermediates  Uncontrolled cell recurrence AKT replication is inhibited • As a multiple RTK inhibitor, it can be first-line Nuclear  Ensures that damaged or treatment for better results Inhibition of DNA‟s membrane mutated DNA does not • Can be used by itself or with chemo for better and topoisomerase2 get passed on to daughter faster results Inhibition of G1-S transition cells • Reasonable cost compared to cancer drugs G1 S Cell LD50: 10.0g/kg membrane Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Bone Marrow or Blood Disease Nail clubbing and Cancer (Lymphoma, Leukemia, Anemia, etc.) NAIL CLUBBING Total # of # cases w/ Neoplastic Diseases % Cancer cases clubbing Mesothelioma 77 23 29.9 • Lung cancer (from asbestosis) (opaque nails) Bronchogeneic carcinoma 111 32 28.9 • Lymphoma Pleural Tumors 21 3 14.3 • Leukemia Lymphoma 40 6 15 • Breast cancer Intrathoracic Hodgkin‟s in 5 5 100 Shell-Shaped/Triangular Nails • Colon cancer, etc children Nasopharyngeal carcinoma 90 6 6.7 Whenever you have these nails, check your Hgb, WBC, RBC levels Source: J American Academy of Dermatology. June 2005; 52(6): 1020-28 Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc.

Extracts of Hippophae and Vertical ridges on nails Rhodiola • Extracts of Hippophae, Rhodiola (DNA repair) • Extracts of Salvia, Carthamus, Paeonia, • Aging Ligusticum (For cardiovascular conditions) • Adrenals • Extracts of Cyperus, Curcuma, Astragalus (For • DNA repair for cancer cells estrogen-related problems) • Kidneys • Lutein, Bilberry, Alisma, Cornus Extracts (Eye •  Oxygen (Cancer cells cannot health, hearing, bones, hair) • Vitamin deficiency grow in aerobic environments) • Asparagus Extract (Kidneys,  immunity, heart) • Peripheral blood • Mitochondrial DNA repair Consumers believe genes and lifestyle affect aging more vessel disease than external products • More energy for cancer patients 69% of consumers reported the earlier one starts using • Neurasthenia age prevention remedies, the better Source: “„Cause‟meceuticals.” Natural Products Insider. July 18, 2011. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 27 Extracts of Hippophae and Rhodiola may Mitochondrial Dysfunction Extracts of Hippophae and Rhodiola promotes protect and repair damaged DNA (Comet Test) • When mitochondrial function is low, lactic DNA Repair for Anti-Aging, Healing acid cannot be converted to energy, causing • Deficiencies in DNA repair show acidosis – premature onset of neurodegenerative • Not enough cell energy supply leads to: age-related diseases –  Muscle strength - Liver disease – Retarded growth - Kidney failure – shortening of lifespan – Induced epilepsy/seizures - Sudden stroke • OxyPower prevents DNA damage and Test shows K2Cr2O7-induced 24 hours after the extracts – Heart enlargement - Kidney failure repairs damaged DNA damage of TK6 human were added, DNA damage lymphoblast cells, evident was repaired, as seen by the – Heart failure - Diabetes here as the comet tail absence of the comet tail

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Fingernail easily splits OSTEOPOROSIS Osteoporosis/Osteopenia ARTHRITIS • Adrenals –Chi Energy Vertical • Lack of stomach acid ridges like –Digestron beads on a string

Thin Nails Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Rehmannia, Corydalis, Extracts of Rehmannia, Corydalis, Dioscorea, Lycium for Osteoporosis Dioscorea, Lycium on Osteoporosis • Improves bone density Extracts of Gastrodia, Angelica, 70 Ligusticum Functions 54.17% • Enhances bone calcium content 60 96 cases 44.79% • Inhibits calcium loss from bones 50 • Pain, Migraine • Nervous System • Does not affect estrogen levels 40 • Dizziness • Muscle Ache • Recommended for osteoporosis patients who 30 • Numbness • Paralysis 20 have or are at risk for estrogen-related 10 1.5% • Arthritis • Intervertebral Disc conditions such as cysts, fibroids, breast 0 •  Blood Pressure Herniation cancer, etc Effective Improved No Change • Fibromyalgia • Calming effect

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 28 Extracts of Gastrodia, Angelica, and Aloe, Coptis, Phellodendron Ointment Ligusticum on 1,137 patients with MEDICINE 80 Neurological Conditions 76.2 “A Simpler Way to Save Lives” 76 73.9 72.6 Could a new medication from China change the world‟s approach to 72 70.6 treating burn injuries? 68.8 69.4 67.7 68 66.7 "The new remedy not only eases pain of burn injuries, according to proponents, but speeds healing, reduces scarring and drastically cuts Effective rate (%) Effective 64 • Burns/Lesions  Infection the cost of saving lives. There is no need for bandages, no topical antibiotics and no sterile isolation. The conventionally treated skin was rough, scarred and marked by patches of excessive or reduced 60 • Wrinkles/Acne  Skin Cancer pigmentation. The herbal treated flesh was now "supple and Pain Dizziness Fibromyalgia Tinnitus Lumbar Sciatica Cervical Lumbar Disc unblemished." Disease Vertebra Herniation • Psoriasis/Eczema Newsweek. May 7, 1990, page 68 Source: Beijing Medical University. 1997. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Whole Skin for Burns

Aloe, Coptis, Phellodendron Extracts SILVADENE WHOLE SKIN (Scar-Free Ointment)

ENDORSED BY JONATHAN WRIGHT, MD Make this ointment part of the FIRST AID regimen in Silvadene Whole Skin your home and workplace. 11 days after 15 days after 30 days after

Missed Nail MELANOMA Diagnosis could actually be Black mole on the palm or sole Squamous Cell of the foot: Carcinoma, High chance of Melanoma Richard K. Scher, MD, World Congress melanoma “Amelanotic melanoma occurs more often in the “Fungal Masquerades” of Dermatology February 2003 nail than in the skin.” Richard Scher, MD from the Dermatology Times, Feb.2003, p. 30. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 29 Melanoma and Estrogen • Elevated estrogen levels may be Cherry implicated in Angiomas melanoma etiology • Risk of melanoma was higher for patients who did not receive anti-estrogens Ref: Cancer Prev Res. 2012. 5(1): 82-8. Squamous Cell Myxoma Melanoma (dark colored) Carcinoma Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Prevent Skin Skin Cancer Extracts of Raphanus, Crataegus, Cancer Protocol Alisma, and Garcinia • Avoid sun • Sea Cucumber Ext exposure • Bolbostemma Ext • Extracts of Aloe, • Removes fat by 51% • Asparagus Extract Coptis, . Extracts of Raphanus, Crataegus, Alisma, –If taken before meals Phellodendron • Reishi Spore Garcinia Extract • Burns fat faster • Asparagus Extract . Tyrosine and Paeonia Extract (organic folic acid) . Extracts of Cyperus, Curcuma, Astragalus –If taken before exercise • AGG (Antioxidant) (for belly fat)

Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Extracts of Raphanus, Crataegus, Alisma, Garcinia Tyrosine and Paeonia Extracts Removes ADP, Promotes the fat-burning process to control weight • Increases metabolic rate • Increases serotonin and norepinephrine levels ENERGY FOR BODILY • Induces a happy feeling, reducing cravings ACTIVITY for foods and promoting faster fat burning

ATP ADP + P Extracts of Cyperus, Curcuma, (INHIBITION) Astragalus for belly fat Copyright © 2012 Chi‟s Enterprise, Inc. FAT • Reduces abdominal fat by inhibiting aromatase Reproduction of this work in any form, in whole or in part, by any means, DEGRADATION electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in • The belly has the highest amount of aromatase writing from Chi‟s Enterprise is strictly prohibited at the risk of legal action. Exercise: Consume Energy (ATP) Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. Copyright. Chi‟s Enterprise, Inc. 30