ACTC1 monoclonal antibody, clone Gene Alias: ACTC, CMD1R, CMH11

RM257 Gene Summary: Actins are highly conserved proteins that are involved in various types of cell motility. Catalog Number: MAB15136 Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded Regulation Status: For research use only (RUO) helix. Each actin can bind to four others. The protein Product Description: Rabbit monoclonal antibody encoded by this gene belongs to the actin family which is raised against synthetic peptide of human ACTC1. comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle Clone Name: RM257 tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated Immunogen: A synthetic peptide corresponding to with idiopathic dilated cardiomyopathy (IDC) and familial N-terminus of human ACTC1. hypertrophic cardiomyopathy (FHC). [provided by RefSeq] Host: Rabbit

Reactivity: Human,Mouse

Applications: IHC-P, WB-Ti (See our web site product page for detailed applications information)

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Form: Liquid

Purification: Protein A affinity purification

Isotype: IgG

Recommend Usage: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500) Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user.

Storage Buffer: In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)

Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 70

Gene Symbol: ACTC1

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