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Southern Source: Globocan 2020

Number of new cases in 2020, both sexes, all ages

Colorectum 123 588 (13%)

Breast 120 185 (12.6%) Other cancers 445 191 (46.7%)

Lung 104 391 (11%)

Prostate Bladder 98 213 (10.3%) 61 480 (6.5%)

Total: 953 048

Number of new cases in 2020, males, all ages Numbers at a glance

Prostate Total population 98 213 (18.8%) 153422604 Other cancers 212 436 (40.6%) Number of new cases Lung 74 009 (14.1%)

Stomach 18 628 (3.6%) 953048

Colorectum Number of deaths Bladder 71 009 (13.6%) 48 889 (9.3%) Total: 523 184 423090 Number of new cases in 2020, females, all ages Number of prevalent cases (5-year)

Breast 2779886 120 185 (28%)

Other cancers Data source and methods 186 009 (43.3%)

Incidence

Thyroid Colorectum Population weighted average of the rates of the - 16 714 (3.9%) 52 579 (12.2%) specific countries included in GLOBOCAN 2020.

Mortality Corpus uteri Lung 23 995 (5.6%) 30 382 (7.1%) Population weighted average of the rates of the region- specific countries included in GLOBOCAN 2020. Total: 429 864 Prevalence Summary statistic 2020 Sum of region-specific prevalent cases.

Males Females Both sexes Populations included Population 74 972 555 78 450 049 153 422 604

Number of new cancer cases 523 184 429 864 953 048 , *, Bosnia and , , Age-standardized incidence rate () 317.7 249.8 279.2 , *, , *, , , Risk of developing cancer before the age of 75 years (%) 31.3 23.9 27.4 , , , *, , , Number of cancer deaths 243 964 179 126 423 090 Age-standardized mortality rate (World) 126.9 76.3 98.9 Risk of dying from cancer before the age of 75 years (%) 13.2 8.1 10.5 5-year prevalent cases 1 444 157 1 335 729 2 779 886 Top 5 most frequent cancers excluding non-melanoma skin cancer Prostate Breast Colorectum (ranked by cases) Lung Colorectum Breast Colorectum Lung Lung Bladder Corpus uteri Prostate Stomach Thyroid Bladder

* Country not available in GLOBOCAN 2020 but included in the region The Global Cancer Observatory - All Rights Reserved - March, 2021. Page 1 Source: Globocan

Incidence, Mortality and Prevalence by cancer site

New cases Deaths 5-year prevalence (all ages) Cancer Number Rank (%) Cum.risk Number Rank (%) Cum.risk Number Prop. (per 100 000) Breast 120 185 1 12.6 8.45 28 607 3 6.8 1.44 477 845 609.11 Lung 104 391 2 11.0 3.61 85 635 1 20.2 2.71 123 347 80.40 Prostate 98 213 3 10.3 7.69 20 383 7 4.8 0.59 377 094 502.98 Colon 81 938 4 8.6 2.42 40 195 2 9.5 0.84 233 232 152.02 Bladder 61 480 5 6.5 1.86 17 931 8 4.2 0.33 195 386 127.35 Rectum 39 299 6 4.1 1.30 14 569 9 3.4 0.36 121 187 78.99 Pancreas 30 836 7 3.2 0.84 28 517 4 6.7 0.77 21 408 13.95 Stomach 30 555 8 3.2 0.85 21 456 5 5.1 0.53 46 866 30.55 Non-Hodgkin lymphoma 28 769 9 3.0 1.01 11 284 12 2.7 0.27 90 068 58.71 Kidney 27 293 10 2.9 0.97 10 133 13 2.4 0.26 79 349 51.72 Liver 24 796 11 2.6 0.80 21 243 6 5.0 0.59 23 543 15.35 Corpus uteri 23 995 12 2.5 1.74 5 643 16 1.3 0.28 89 571 114.18 Melanoma of skin 23 915 13 2.5 0.93 4 926 18 1.2 0.15 80 190 52.27 Thyroid 22 407 14 2.4 1.02 1 243 26 0.29 0.03 83 949 54.72 Leukaemia 21 559 15 2.3 0.69 14 441 10 3.4 0.34 61 343 39.98 Brain, central nervous system 15 566 16 1.6 0.60 12 290 11 2.9 0.44 44 850 29.23 Ovary 12 779 17 1.3 0.89 8 015 14 1.9 0.48 36 067 45.97 Lip, oral cavity 12 387 18 1.3 0.42 4 234 20 1.0 0.13 37 743 24.60 Multiple myeloma 12 020 19 1.3 0.36 7 999 15 1.9 0.19 31 631 20.62 Larynx 9 275 20 0.97 0.37 4 529 19 1.1 0.15 30 145 19.65 Cervix uteri 9 053 21 0.95 0.76 3 705 21 0.88 0.25 27 149 34.61 Oesophagus 6 307 22 0.66 0.22 5 564 17 1.3 0.18 7 451 4.86 Testis 5 051 23 0.53 0.52 291 33 0.07 0.03 21 567 28.77 Hodgkin lymphoma 4 681 24 0.49 0.22 973 28 0.23 0.03 18 250 11.90 Oropharynx 3 711 25 0.39 0.16 1 998 23 0.47 0.08 10 895 7.10 Vulva 3 048 26 0.32 0.15 1 293 25 0.31 0.04 9 320 11.88 Mesothelioma 2 941 27 0.31 0.09 2 596 22 0.61 0.07 3 456 2.25 Gallbladder 2 792 28 0.29 0.07 1 938 24 0.46 0.05 2 971 1.94 Hypopharynx 2 664 29 0.28 0.11 1 079 27 0.26 0.04 4 982 3.25 Anus 2 351 30 0.25 0.08 642 31 0.15 0.02 7 335 4.78 Salivary glands 2 168 31 0.23 0.06 930 29 0.22 0.02 7 016 4.57 Kaposi sarcoma 1 660 32 0.17 0.05 226 35 0.05 0.00 5 218 3.40 Nasopharynx 1 584 33 0.17 0.07 746 30 0.18 0.03 5 280 3.44 Penis 1 471 34 0.15 0.10 414 32 0.10 0.02 4 863 6.49 Vagina 553 35 0.06 0.03 247 34 0.06 0.01 1 554 1.98 All cancer sites 953 048 - - 27.40 423 090 - - 10.52 2 779 886 1811.9

Age-standardized (World) incidence rates per sex, top 10 cancers

Males Females

Breast 79.6

Colorectum 40.6 24.5 Lung 43.1 16.4 Prostate 59.1 Bladder 26.5 5.8 Thyroid 5.1 16.5 Non-Hodgkin lymphoma 11.1 7.7 Melanoma of skin 9.2 8.9 Kidney 11.8 5.2 Stomach 10.2 5.0

100 80 60 40 20 0 20 40 60 80 100 ASR (World) per 100 000

Age-standardized (World) incidence and mortality rates, top 10 cancers

Incidence Mortality

Breast 79.6 13.3

Prostate 59.1 7.8 Colorectum 31.9 11.5 Lung 28.7 21.9 Bladder 15.3 3.3 Corpus uteri 14.2 2.4 Thyroid 10.8 0.28 Non-Hodgkin lymphoma 9.3 2.5 Melanoma of skin 9.0 1.4 Kidney 8.3 2.4

100 80 60 40 20 0 20 40 60 80 100 ASR (World) per 100 000

The Global Cancer Observatory - All Rights Reserved - March, 2021. Page 2