-Isomerase A6 Recombinant Protein Cat. No.: 91-476

Protein Disulfide-Isomerase A6 Recombinant Protein

Specifications

SPECIES: Human

SOURCE SPECIES: Human Cells

SEQUENCE: Leu20-Leu440

FUSION TAG: C-6 His tag

TESTED APPLICATIONS:

APPLICATIONS: This recombinant protein can be used for biological assays. For research use only.

PREDICTED MOLECULAR 47.2 kD WEIGHT:

Properties

Greater than 95% as determined by reducing SDS-PAGE. PURITY: Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

PHYSICAL STATE: Liquid

Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH BUFFER: 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

September 27, 2021 1 https://www.prosci-inc.com/protein-disulfide-isomerase-a6-recombinant-protein-91-476.html Store at -20˚C, stable for 6 months after receipt. STORAGE CONDITIONS: Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: PDIA6

Protein Disulfide-Isomerase A6, Protein 5, ER Protein 5, ERp5, ALTERNATE NAMES: Protein Disulfide Isomerase P5, Domain-Containing Protein 7, PDIA6, P5, TXNDC7

ACCESSION NO.: Q15084

GENE ID: 10130

Background and References

Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an in the endoplasmic reticulum in which catalyzes the formation and breakage of disulfide bonds between cysteine residues within as they fold. The PDIA6 expressed in platelets, its BACKGROUND: functions as a that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1. PDIA6 also plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 2 https://www.prosci-inc.com/protein-disulfide-isomerase-a6-recombinant-protein-91-476.html