Eili Y. Klein
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Eili Y. Klein Fellow, Center for Disease Dynamics, Economics & Policy 1400 I Street, NW, Suite 500 202.328.5197 • [email protected] EDUCATION Princeton University, Princeton, NJ PhD in Ecology and Evolutionary Biology, 2012 Thesis: Anti-malarial Drug Resistance Johns Hopkins University School of Advanced International Relations, Washington, DC Master of Arts, International Health Policy, 2005 Columbia University, New York, NY Bachelor of Arts, Economics, 1998 PROFESSIONAL EXPERIENCE Center for Disease Dynamics, Economics & Policy 2012- Fellow 2010-2012 Research Associate Johns Hopkins University 2012- Faculty, Department of Emergency Medicine 2017- Faculty, Department of Epidemiology Resources for the Future 2005-2010 Research Associate; Research Assistant RESEARCH INTERESTS Improving policy and clinician decision-making using health information technology and mathemati- cal modeling. Surveillance of antimicrobial resistance. Impact of behavior and social structure on the spread of infectious disease. Impact of antimicrobial drug resistance on ecology and epidemiology of disease. Economic epidemiology. Mathematical and theoretical ecology. Evolution of pathogen-host interactions. Pathogen competition across space and scale. Influenza viral evolution. HONORS & AWARDS Hartwell Foundation Biomedical Research Fellowship (2015) NIH Loan Repayment Program (2013-15,2016-18) Johns Hopkins Emergency Department Research Day Award for Best Research Presentation (2012) The May Fellowship, Princeton University (2008-09,2010-11) Harold W. Dodds Honorific Fellowship, Princeton University (2011-12) C. Grove Haines Prize, JHU-SAIS (2004) PUBLICATIONS JOURNAL ARTICLES 2018 Klein Eili Y., Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin S, Goossens H, Laxmi- narayan R (in press) “Global increase and geographic convergence in antibiotic consumption between 2000 and 2015” Proceedings of the National Academy of Sciences. Eili Y. Klein Page 2 Townsend, Jennifer, Kittane Srinivas Vishnupriya, Eili Klein, Brian Spoelhof, Jonathan Zenilman (in press) “Hospitalist ID service in academic medical centers: a win-win for hospitalists and fellows” Southern Medical Journal. Broniatowski, David A., Eili Y. Klein, Larissa May, Elena M. Martinez, Chelsea Ware, Valerie F. Reyna. (in press) “Patients’ and Clinicians’ Perceptions of Antibiotic Prescribing for Upper Respiratory Infections in the Acute Care Setting” Medical Decision Making. Klein, Eili Y., Katie Tseng, Daniel J. Morgan, Ramanan Laxminarayan (2018) “Reply to author” Clinical Infectious Diseases ciy119. DOI: 10.1093/cid/ciy119. Klein, Eili Y., Deena Blumenkrantz, Adrian Serohijos, Eugene Shakhnovich, Jeong-Mo Choi, Joo V. Rodrigues, Brendan D. Smith, Andrew P. Lane, Andrew Feldman, Andrew Pekosz (2018) “Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics” mSphere 3(1):e00554-17. DOI: 10.1128/mSphereDirect.00554-17. 2017 Robinson, Matthew, Dileep Kadam, Anju Kagal, Sandhya Khadse, Aarti Kinikar, Chhaya Valvi, Anita Basavaraj, Renu Bharadwaj, Ivan Marbaniang, Savita Kanade, Priyanka Raichur, Jonathan Sachs, Eili Klein, Sara Cosgrove, Amita Gupta, Vidya Mave (2017) “Antibiotic utilization and the role of suspected and diagnosed mosquito borne illness among adults and children with acute febrile illness in Pune, India” Clinical Infectious Diseases. DOI: 10.1093/cid/cix1059. Klein, Eili Y., Nestor Mojica, Wendi Jiang, Sara E. Cosgrove, Edward Septimus, Daniel J. Morgan, and Ramanan Laxminarayan (2017) “Trends in Methicillin-Resistant Staphylococcus aureus Hospi- talizations in the United States, 2010-2014” Clinical Infectious Diseases 65(11):1921-1923. DOI: 10.1093/cid/cix640. Klein, Eili Y., Scott Levin, Matthew F. Toerper, Michael Makowsky, Tim Xu, Gai Cole, and Ga- bor Kelen (2017) “The Effect of Medicaid Expansion on Utilization in Maryland Emergency Depart- ments” Annals of Emergency Medicine 70(5):607-614.e1. DOI: 10.1016/j.annemergmed.2017.06.021. Klein, Eili Y., Elena M. Martinez, Larissa May, Mustapha Saheed, Valerie Reyna, and David A. Broniatowski (2017) “Categorical Risk Perception Drives Variability in Antibiotic Prescribing in the Emergency Department: A mixed methods observational study” Journal of General Internal Medicine 32(10):1083-1089. DOI: 10.1007/s11606-017-4099-6. Makowsky, Michael and Eili Y. Klein (2017) “Identifying the Relationship between Length of Hospital Stay and the Probability of Readmission” Applied Economic Letters 25(6):375-380. DOI: 10.1080/13504851.2017.1324605. Gandra, Sumanth, Anna Trett, Eili Y Klein, Ramanan Laxminarayan (2017) “Is Antimicrobial Resistance a Bigger Problem in Tertiary Care Hospitals than in Small Community Hospitals in the United States?” Clin Infect Dis 65(5):860863. DOI: 10.1093/cid/cix413. Hinson, Jeremiah S., Michael R. Ehmann, Derek M. Fine, Elliot K. Fishman, Richard E. Rothman, and Eili Y. Klein (2017) “Risk of Acute Kidney Injury Following Intravenous Contrast Media Administration: A Five-Year Retrospective Analysis” Annals of Emergency Medicine 69(5):577586. DOI: 10.1016/j.annemergmed.2016.11.021. Larissa May MD, Eili Y. Klein, Elena M. Martinez, Nestor Mojica, and Loren G. Miller (2016) Eili Y. Klein Page 3 “Incidence and Factors Associated with Emergency Department Visits for Recurrent Skin and Soft Tissue Infections in Patients in California, 2005-2011” Epidemiology and Infection. 145(4):746-754. DOI: 10.1017/S0950268816002855. 2016 Logan, Latania K., Sumanth Gandra, Siddhartha Mandal, Eili Y. Klein, Jordan Levinson, Robert A. Weinstein, Ramanan Laxminarayan (2016) “Multi-drug and Carbapenem-Resistant Pseudomonas aeruginosa in Children, United States, 1999-2012” Journal of the Pediatric Infectious Diseases So- ciety. DOI: 10.1093/jpids/piw064. Klein, Eili Y., Bradley Monteforte, Alisha Gupta, Wendi Jiang, Larissa May, Yu-Hsiang Hsieh, an- dAndrea Dugas (2016) “The Frequency of Influenza and Bacterial Coinfection: A Systematic Review and Meta-Analysis” Influenza and Other Respiratory Viruses 10(5):394-403. DOI: 10.1111/irv.12398. Gandra, Sumanth, Eili Y. Klein, Suraj Pant, Surbhi Malhotra-Kumar, and Ramanan Laxmi- narayan (2016) “Faropenem Consumption is Increasing in India” Clin Infect Dis 62(8):1050-1052. DOI:10.1093/cid/ciw055. Pant, Suraj, Eili Y. Klein, Sumanth Gandra, Ramanan Laxminarayan (2016) “Tracking trends in antibiotic effectiveness using the Drug Resistance Index” International Journal of Infectious Diseases 45(Supp 1):109. DOI: 10.1016/j.ijid.2016.02.280. 2015 Levy M, Broccoli M, Cole G, Jenkins JL, Klein EY. (2015) “An Analysis of the Relationship Between the Heat Index and Arrivals in the Emergency Department” PLOS Currents Disasters, Edition 1. doi: 10.1371/currents.dis.64546103ed4fa0bc7c5b779dd16f5358. Cole, Gai, Dicky Stefanus, Heather Gardner, Matthew J Levy, Eili Y Klein (2015) “The impact of interruptions on the duration of nursing interventions: a direct observation study in an academic emergency department” BMJ Quality & Safety 25:457465. Klein, Eili Y., David L. Smith, Justin M. Cohen, Ramanan Laxminarayan (2015) “Cost-effectiveness Analysis of Targeting Children Compared to the Whole Population for Continuing Subsidies for ACTs Using a Bioeconomic Malaria Model” Journal of the Royal Society Interface 12(107): 20141356. Klein, Eili Y., Michael Makowsky, Megan Orlando, Erez Hatna, Nikolay P. Braykov, Ramanan Laxminarayan (2015) “Influence of provider and urgent care density across different socioeconomic strata on outpatient antibiotic prescribing in the USA” Journal of Antimicrobial Chemotherapy 70(5): 1580-1587. 2014 Broniatowski, David A., Eili Y. Klein, Valerie Reyna (2014) “Germs are Germs, and Why Not Take a Risk?: Patients’ Expectations for Prescribing Antibiotics in an Inner City Emergency Department” Medical Decision Making 35(1):60-67. Kouyos, Roger D., C. Jessica E. Metcalf, Ruthie Birger, Eili Y. Klein, Pia Abel zur Wiesch, Peter Ankomah, Nimalan Arinaminpathy, Tiffany L. Bogich, Sebastian Bonhoeffer, Charles Brower, Geoffrey Chi-Johnston, Ted Cohen, Troy Day, Bryan Greenhouse, Silvie Huijben, Joshua Metlay, Nicole Mideo, Laura C Pollitt, Andrew F. Read, David L. Smith, Claire Standley, Nina Wale, Bryan Eili Y. Klein Page 4 Grenfell (2014) “The path of least resistance: aggressive or moderate treatment?” Proceedings of the Royal Society, Series B: Biological Sciences 281(1794): 20140566. May, Larissa, Gudger G, Armstrong P, Brooks G, Hinds P, Bhat R, Moran G, Schwartz L, Cosgrove SE, Klein EY, Rothman RE, Rand C (2014) “Multisite Exploration of Clinical Decision-Making for Antibiotic Use by Emergency Medicine Providers Using Quantitative and Qualitative Methods” Infection Control and Hospital Epidemiology 35(9): 1114-1125. Klein, Eili Y., Serohijos AWR, Choi J-M, Shakhnovich EI, Pekosz A (2014) “Influenza A H1N1 Pandemic Strain Evolution - Divergence and the Potential for Antigenic Drift Variants” PLoS ONE 9(4): e93632. Smith, David L., T. Alex Perkins, Robert C Reiner, Christopher M. Barker, Tianchan Niu, Luis Fernando Chaves, Alicia M. Ellis, Dylan B George, Arnaud Le Menach, Juliet R. C. Pulliam, Donal Bisanzio, Caroline Buckee, Christinah Chiyaka, Derek A. T. Cummings, Andres J. Garcia, Michelle L. Gatton, Peter W. Gething, David M. Hartley, Geoffrey Johnston, Eili Y. Klein, Edwin Michael, Alun L. Lloyd, David M. Pigott, William K. Reisen, Nick Ruktanonchai, Brajendra K. Singh, Jeremy Stoller, Andrew J. Tatem, Uriel Kitron, H. Charles J. Godfray, Justin M. Cohen, Simon I. Hay, Thomas W. Scott (2014) “Recasting the Theory of Mosquito-Borne Pathogen Transmission