IL36G Rabbit Pab

Leader in Biomolecular Solutions for Life Science IL36G Rabbit pAb Catalog No.: A10165 Basic Information Background Catalog No. The protein encoded by this gene is a member of the interleukin 1 cytokine family. The A10165 activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Observed MW Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are 18kDa reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction Calculated MW or herpes simplex virus infection. This gene and eight other interleukin 1 family genes 18kDa form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. Category Primary antibody Applications WB Cross-Reactivity Mouse Recommended Dilutions Immunogen Information WB 1:500 - 1:2000 Gene ID Swiss Prot 215257 Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of mouse IL36G (NP_705731.2). Synonyms IL36G;IL-1F9;IL-1H1;IL-1RP2;IL1E;IL1F9;IL1H1;IL1RP2 Contact Product Information www.abclonal.com Source Isotype Purification Rabbit IgG Affinity purification Storage Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. Validation Data Western blot analysis of extracts of mouse liver, using IL36G antibody (A10165) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. Antibody | Protein | ELISA Kits | Enzyme | NGS | Service For research use only. Not for therapeutic or diagnostic purposes. Please visit http://abclonal.com for a complete listing of recommended products..

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Data Sheet Huil36g (152 A.A.)
Growth Factor Data Sheet GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption! Interleukin-36G (IL36G) is a pro-inflammatory cytokine that plays an important role in the pathophysiology of several diseases. IL36A, IL36B and IL36G (formerly IL1F6, IL1F8, and IL1F9) are IL1 family members that signal through the IL1 receptor family members IL1Rrp2 (IL1RL2) and IL1RAcP. IL36G is secreted when transfected into 293-T cells and could constitute part of an independent signaling system analogous to that of IL1A and IL1B receptor agonist and interleukin-1 receptor type I (IL1R1). Furthermore, IL36G also can function as an agonist of NFκB activation through the orphan IL1- receptor-related protein 2. Human IL36G (152 a.a.) shares 58%, 59%, 68% and 69% amino acid sequence identity with mouse, rat, bovine and equine IL36G, respectively, and 23-57% amino acid sequence identity with other family members. Catalog Number 1110-36F Product Name IL36G (IL-36 gamma), Human (152 a.a.) Recombinant Human Interleukin-36γ IL36G, IL36γ Interleukin 1 Homolog 1 (IL1H1) Interleukin 1-Related Protein 2 (IL1RP2) Interleukin 1 Family, Member 9 (IL1F9) Source Escherichia coli MW ~17.0 kDa (152 amino acids) Sequence SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND Accession Number Q9NZH8 Purity >95% by SDS-PAGE and HPLC analyses Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to induce IL-8 secretion by human preadipocytes is less than 10 ng/ml, corresponding to a specific activity of >1 × 105 IU/mg.
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Huil36g 169 Data Sheet
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Genetic Determinants of Circulating Interleukin-1 Receptor Antagonist Levels and Their Association with Glycemic Traits
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IL36G Blocking Peptide (CDBP5559) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use
IL36G blocking peptide (CDBP5559) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] Immunogen 13 amino acids near the carboxy terminus of human IL-36G. Nature Synthetic Expression System N/A Species Reactivity Human Conjugate Unconjugated Applications Used as a blocking peptide in immunoblotting applications. Procedure None Format Liquid Concentration 200 μg/mL Size 0.05mg Preservative None Storage -20°C ANTIGEN GENE INFORMATION Gene Name IL36G interleukin 36, gamma [ Homo sapiens (human) ] Official Symbol IL36G 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms IL36G; interleukin
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Effects of Cranberry Extracts on Gene Expression in THP‐
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Il1f10 (NM 153077) Mouse Tagged ORF Clone – MR223925 | Origene
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32-1532: IL36G Recombinant Protein Description Product Info Application Note
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Il1f10 (NM 153077) Mouse Tagged ORF Clone Lentiviral Particle Product Data
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Abstract Background: Tuberculosis (TB) Is a Deadly Transmissible Disease That Can Infect Almost Any Body-Part of the Host but Is Mostly Infect the Lungs
bioRxiv preprint doi: https://doi.org/10.1101/414110; this version posted September 14, 2018. The copyright holder for this preprint (which was Stagenot certified specific by peer classification review) is the author/funder. of DEGs All rights via reserved. statistical No reuse profiling allowed without and permission. network analysis reveals potential biomarker associated with various stages of TB Aftab Alam1. Nikhat Imam2, Mohd Murshad Ahmed1, Safiya Tazyeen1, Anam Farooqui1, Shahnawaz Ali1, Md. Zubbair Malik1 and Romana Ishrat*1 1Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi-110025 (India) 2Institute of Computer Science & Information Technology, Department of Mathematics, Magadh University, Bodh Gaya-824234 (Bihar, India) Abstract Background: Tuberculosis (TB) is a deadly transmissible disease that can infect almost any body-part of the host but is mostly infect the lungs. It is one of the top 10 causes of death worldwide. In the 30 high TB burden countries, 87% of new TB cases occurred in 2016. Seven countries: India, Indonesia, China, Philippines, Pakistan, Nigeria, and South Africa accounted for 64% of the new TB cases. To stop the infection and progression of the disease, early detection of TB is important. In our study, we used microarray data set and compared the gene expression profiles obtained from blood samples of patients with different datasets of Healthy control, Latent infection, Active TB and performed network-based analysis of DEGs to identify potential biomarker. We want to observe the transition of genes from normal condition to different stages of the TB and identify, annotate those genes/pathways/processes that play key role in the progression of TB disease during its cyclic interventions in human body.
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Review—Current Concepts in Inflammatory Skin Diseases
International Journal of Molecular Sciences Review Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and Psoriasis Julius Schwingen * , Mustafa Kaplan and Florian C. Kurschus * Department of Dermatology, Heidelberg University Hospital, 69120 Heidelberg, Germany; [email protected] * Correspondence: [email protected] (J.S.); fl[email protected] (F.C.K.) Received: 16 December 2019; Accepted: 16 January 2020; Published: 21 January 2020 Abstract: During the last decades, high-throughput assessment of gene expression in patient tissues using microarray technology or RNA-Seq took center stage in clinical research. Insights into the diversity and frequency of transcripts in healthy and diseased conditions provide valuable information on the cellular status in the respective tissues. Growing with the technique, the bioinformatic analysis toolkit reveals biologically relevant pathways which assist in understanding basic pathophysiological mechanisms. Conventional classification systems of inflammatory skin diseases rely on descriptive assessments by pathologists. In contrast to this, molecular profiling may uncover previously unknown disease classifying features. Thereby, treatments and prognostics of patients may be improved. Furthermore, disease models in basic research in comparison to the human disease can be directly validated. The aim of this article is not only to provide the reader with information on the opportunities of these techniques, but to outline potential pitfalls and technical limitations as well. Major published findings are briefly discussed to provide a broad overview on the current findings in transcriptomics in inflammatory skin diseases. Keywords: inflammatory skin diseases; transcriptomics; RNA-Seq; microarray; scRNA-Seq; psoriasis; atopic dermatitis; contact dermatitis; acne; eczema 1.
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Title Epithelial TRAF6 Drives IL-17-Mediated Psoriatic
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