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Brochure TMR Magnetic Stirrer with Fault Indicating System 01.2012

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Brochure TMR Magnetic Stirrer with Fault Indicating System 01.2012 • Magnetic agitators with malfunction indicating system Dipl.-Ing. V. TEICHMANN stirring rod for applications in pharmaceutical production. Measurement, Control & Process Engineering • Metering units for conductivity and resistance of liquids. D - 35094 Lahntal - Kernbach • Temperature probes • Vacuum tight measuring lines passages • Special developments and production. TMR magnetic stirrer with fault indicating system for the stirring staff combines the advantage of the magnetic drive with the safety of a mechanically coupled stirring unit. Compact magnetic stirrer Table-top units - operation via front panel or remote control TMR-102-SK TMR-102-FSKV 7 x TMR-102-FSKV separated under a water bath System magnetic stirrer Control unit and magnetic stirring unit separated MAGNETRONIC DSZ-5010 MAGNETRONIC DSS-50 TMR-102-S Magnetic stirrer system on a mobile undercarriage with separate container trolley. MAGNETRONIC DSS-50 with TMR-102-S and TUW-DSS11 Front panel and connection panel MAGNETRONIC DSS-50 TMR -10 2-…: Magnetic drive field Ø 100 mm for stirring volumes up to 300 litre Page 1 TMR-202-…: Magnetic drive field Ø 200 mm for stirring volumes up to 1000 litre Subject to technical modifications 01.2012 • Magnetic agitators with malfunction indicating system Dipl.-Ing. V. TEICHMANN stirring rod for applications in pharmaceutical production. Measurement, Control & Process Engineering • Metering units for conductivity and resistance of liquids. D - 35094 Lahntal - Kernbach • Temperature probes • Vacuum tight measuring lines passages • Special developments and production. Accessories for TMR magnetic stirrer NEW - Product container with special metal-fused glass flange in the base as maintenance-free storage for freewheeling Teflon stirring staffs. Outstanding Advantages • Practically wear-free operation of the stirring staff. No Teflon abrasion that would otherwise occur on stainless steel bases. • Dead-leg free. • Easy to clean and sterilise, CIP and SIP capable. • No bearing points to be monitored in the container, since stirring staffs are freewheeling. • Even small volumes can be stirred. • Perfect to discharge - Negligible product losses. • Stirring stuff and support flange can easily be adapted to different container sizes and geometries. Cross section container Container Base Screw O-ring seal Metal fused Teflon-coated Sample base plate seamless glass flange stirring staff tube Page 2 Subject to technical modifications 01.2012 • Magnetic agitators with malfunction indicating system Dipl.-Ing. V. TEICHMANN stirring rod for applications in pharmaceutical production. Measurement, Control & Process Engineering • Metering units for conductivity and resistance of liquids. D - 35094 Lahntal - Kernbach • Temperature probes • Vacuum tight measuring lines passages • Special developments and production. Accessories for TMR magnetic stirrers • Magnetic stirring staffs with Teflon sheathing. • Magnetic stirring staffs with stainless steel sheathing and ceramic bearing. Magnetic stirring staffs of high quality and surface finish for use for pharmaceutical laboratory and production applications. • Hermetically sealed sheathing made of modified tetrafluoroethylene in a sintered or welded version. • Food-safe in accordance with FDA CFR21, §175,300 and Food Contact Notification (FCN) No. 40. • Thickness of the Teflon layer > 2 mm. • Average Roughness Height Ra < 1 µ. • Central collar for clean concentricity. • Magnetic core made of Alnico 500. • Application temperature - 200 °C to + 250 °C. • Pressure-resistant up to 3 bar absolute. Freewheeling Teflon encapsulated stirring staffs No. Type Description Recommended stirring volume 1 B 6060250 Stirring staff 40x40x250 mm with collar 100 x 60 x 60 mm Up to 1000 litre 2 B 34150 Stirring staff Ø 30 x 150 mm with collar Ø 34 x 30 mm 300 litre B 25155 Stirring staff Ø 22 x 155 mm with collar Ø 25 x 30 mm 200 litre 3 B 25110 Stirring staff Ø 22 x 110 mm with collar Ø 25 x 25 mm 100 litre 4 B 16100 Stirring staff Ø 14 x 100 mm with collar Ø16 x 20 mm 20 litre Central stainless-steel encapsulated stirring staffs with ceramic bearings No. Type Description Recommended stirring volume . 5 TER-4040210 Stirring staff 40 x 40 x 210 mm, T-DR3 coating 500 litre K 34/2 Stirring staff 40 x 40 x 210 mm, material 1.4435 3.1 B 500 litre 6 K 26/2 Stirring staff Ø 30 x 160 mm, material 1.4435 3.1 B 300 litre 7 K 22/2 Stirring staff Ø 26 x 130 mm, material 1.4435 3.1 B 200 litre 8 Ceramic bearings 10 +13 mm inner diameter, material CR101 NOTE The given stirring volumes refer to operation with TMR magnetic stirrers. Page 3 Subject to technical modifications 01.2012 Device and functional description 1. Introduction Page 4 The TMR magnetic stirrer was developed for the pharmaceutical industry and biotechnology to thoroughly mix sensitive products in a sterile and gentle way, and to make the FDA and GMP-conform documentation of the stirring process possible. Further applications can be found increasingly in industrial branches where sterile or toxic liquids are stirred e.g. in glass vessels. For this purpose, the devices have been designed without compromise for permanent use in the production process and work maintenance-free for years even under difficult environmental conditions. The integrated fault indicating system for the stirring staff combines the advantage of the magnetic drive with the safety of a mechanically coupled stirring unit: ••• Sterility, since no shafts are routed through the product space. ••• Universal use of a wide range of different container types made of non-magnetic materials, such as various stainless steels, plastics or glass. ••• Easy cleaning and sterilising of the stirrer staff, no complicated storage geometry as with impeller stirring units. CIP and SIP-friendly design. Sterile containers can be sterilised with stirring staff in the autoclave. ••• One magnetic stirring system can be used for several batching tanks, since the drive unit is not connected to the container. With mobile containers, for example, batching can be carried out in a different production area. ••• Powerful and centring magnetic drive field, so that distances of a few centimetres between the stirring unit and the magnetic staff can be realised. ••• Fault message when the magnetic force closure between drive and stirring staff breaks down, which can happen with magnetic stirrers on account of the system and leads to uncontrolled standstill of the stirring function despite rotating stirring unit. "Automatic stirring staff catch" for the automatic reestablishment of the stirring function. ••• Time sequence control for the linear speed reduction at filling stations for e.g. vaccines containing adjuvants in order to avoid foam forming when the filling level in the product container drops. ••• Clear documentation of the stirring process according to FDA and GMP guidelines through recording of speed curves and fault message voltage by means of a recorder. Sterile can with centrally running 500 litre glass container with freewheeling stirring staff on the lifter tube. Teflon-coated special stirring staff. R = 400mm Dipl.-Ing. V. TEICHMANN Meß-Regel-Verfahrenstechnik D - 35094 Lahntal-Kernbach Dipl.-Ing. V. TEICHMANNTEICHMANN Meß-Regel-Verfahrenstechnik Drehfeld - Durchmesser 200 mm für D - 35094 Lahntal-Kernbach Betrieb 2 - polige Rührstäbe, Länge 150 - 250 mm. Drehfeld - Durchmesser 100 mm für BetriebBetrieb Integrierter Magnetstabsensor für die Störung 2 - polige Rührstäbe, Länge 80 - 150 mm. Störmeldung Rührstab / Antrieb. Rührstab Integrierter Magnetstabsensor für die Störung Störmeldung Rührstab / Antrieb Rührstab Beim Betrieb des Gerätes Warnung vor magnetischem Feld, sind die Hinweise gemäß auch bei abgeschaltetem Gerät. der Beschilderung und Warnung vor magnetischem Feld, Beim Betrieb des Gerätes der Bedienungsanleitung sind die Hinweise gemäß Gefahrenhinweise beachten ! zu beachten ! auch bei abgeschaltetem Gerät. der Beschilderung und Gefahrenhinweise beachten ! der Bedienungsanleitung zu beachten ! Dipl.-Ing. V. TEICHMANN • Measurement, Control & Process Engineering • Am Bornacker 6 • D-35094 Lahntal-Kernbach Telephone: +49 (0) 6420 7666 Facsimile: +49 (0) 6420 7868 E-mail: [email protected] Device and functional description 2. Function Page 5 TMR magnetic stirrers produce a 2-pole permanently magnetic rotating field with a diameter of 100 mm (TMR-102-...) respectively 200 mm (TMR-202-...) . The magnetic field lines are bundled by special pole shoes and project almost vertically from the work surface. There is a magnetic staff in the product container that aligns itself in the drive field on account of the magnetic attractive force and is rotated synchronously by this field. This allows stirring unit and magnetic staff to rotate at the same speed in uninterrupted operation. In contrast to the directly driven stirring unit, however, the forced closure between the drive and stirring staff can break off with the magnetic stirrer, so that the stirring process is interrupted despite the fact that the stirring unit is still rotating and thus producing a speed indication . This operational problem cannot be detected without visual inspection and requires the use of supervisory personnel as well as containers with optical control possibilities. Since the stirring staff cannot synchronise itself automatically after a break in connection, the stirring process remains interrupted until the speed has been reduced manually. In sensitive areas of chemical-pharmaceutical laboratory and production technology, automatic
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