Nadine Saleh SALAMEH Mail: [email protected] Married, Two children Tel: +961.3.374746 French-Lebanese
Chair of the Master of Public Health, Lebanese University Professor of Pharmaco-Epidemiology, Biostatistics and Pharmacology Invited Professor at “Université Paris Descartes – Sorbonne Paris Cité” PhD in Pharmaco-Epidemiology
Diploma in Biostatistics Master of clinical pharmacology
Doctor of Pharmacy (Clinical Pharmacy) Bachelor of Sciences in Pharmacy
Work Experience
Administrative responsibilities
October 2017- Current: Vice president of the epidemiology team at the faculty of Public Health
June 2016-Current: Responsible for the agreement between Paris Saclay and the Faculty of Public Health (Section II) at Lebanese University. An agreement of a double Franco-Lebanese diploma for the master of public health at the Faculty will be started from September 2017.
January 2016-Current: Member of the committee of masters at Lebanese University
October 2015-Current: Head of the pharmacoepidemiology surveillance unit at CERIPH
January 2015- Current: Chair of the Master of Public Health, option: Methodology and Statistics in Biomedical Research, Faculty of Public health, Lebanese University
In this position, duties are the following:
- Management and organization of the master - Follow up of academic affairs, both teaching and research - Coordinating the master program for co-diplomation with Paris-Saclay -Teaching pharmacoepidemiology, biostatistics, metaanalysis -Working on establishing new projects: new university diploma
January 2013- January 2015: Coordinator of the Research Master Program of Epidemiology & Biostatistics, Faculty of Public health, Lebanese University
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Jan 2013-July 2015: Member of the Center for Systematic Reviews on Health Policy and Systems Research (SPARK) at the American University of Beirut
Dec 2012-Dec 2014: Member of the “Advisory Committee on Antibiotic Use in Lebanon”, WHO, Lebanon. Working on project to increase awareness about antibiotic use and resistance.
Teaching
September 2015-Current: Professor and Research Scientist, Masters in Clinical Pharmacy and Pharmaco- epidemiology, Faculty of Pharmacy, Lebanese University
September 2015: Promotion to the rank of Professor at the Lebanese University.
Oct 2010-2015: Associate Professor and Research Scientist, Masters in Clinical Pharmacy and Pharmaco- epidemiology, Faculty of Pharmacy, Lebanese University
Oct 2010-Current: Associate Professor and Research Scientist, Masters in Clinical Pharmacy and Pharmaco-epidemiology, Faculty of Public Health, Lebanese University
Feb 2010-Oct 2014: Associate Professor, Notre Dame University, Pharmacology for Nutrition and Nursing Students
Oct 2011-Current: Associate Professor, Faculty of Dentistry, Lebanese University, Pharmacology for Master students
Sep 2010-Sep 2012: Associate Professor and Research Scientist, Paris XII University, Henri Mondor Teaching Hospital, Paris, France, Pharmacology for Medical students and Nursing
Invited Talks
February 2018: “Introduction to Pharmacoepidemiology” for master of Public Health at Paris Sud University, France.
October 2015: “Cancer Epidemiology in Lebanon”. 23rd Annual Congress of the Lebanese Order of Pharmacists-Biel-Beirut, Lebanon.
August 2013: “Statistics and data management for clinical research”. Principles in Medical Research & GCP Training, Metropolitan -Hilton Hotel- Beirut, Lebanon.
April 2012: “Plan National de Diagnostic et de Soin”. Réseau Huntington de Langue Française (RHLF), annually meeting, Paris, France
April 2011: “International guidelines for care project for Huntington’s Disease”. European Huntington’s disease network, annually meeting, Paris, France
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March 2011: “Insulin resistance and Huntington’s disease”. Réseau Huntington de Langue Française (RHLF), annually meeting, Paris, France.
November 2010: “The pharmacologic effects of corticoids”. Lebanese University, Faculty of Dentistry, Hadath, Lebanon
June 2010: • “Corticosteroids in dentistry”. Lebanese University, Faculty of Dentistry, Hadath, Lebanon • “Mouthwashes in the Lebanese market: mechanism of action, indication, side effects, usage”. Lebanese University, Faculty of Dentistry”, Hadath, Lebanon
Ongoing Research activity
- Antibiotic surveillance in Lebanon: for my diploma of Ability to Direct Research on medication surveillance.
- Health and Environment: Environmental epidemiology
- Implementation of a national risk management system for medication errors in Lebanese hospitals.
- Systematic review of medication errors in hospitalized patients worldwide
- Systematic review analysis about the frequency of misuse of Antibiotics in developed countries versus developing countries.
- Bibliometric analysis of literature on health research in Lebanon: Publications from 2000 to 2017.
- Evaluation of the misuse of drug in Lebanon in different infections disease
PhD projects direction/co-direction/active contribution co-direction and jury participation
Direction/co-direction/active contribution co-direction 1- September 2017-Current: Co-director “ Implémentation d’un système national de gestion de risque des erreurs médicamenteuses dans les hôpitaux libanais : création d’un guichet erreurs médicamenteuses au Liban ”. In collaboration with Patrick Maison, direction de la surveillance medicamenteuse-ANSM-Université Paris Est. Doctorant : Christine Azar, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon 2- September 2017-Current: Co-director “ Exposition aux particules ultrafines et au carbone suie des chauffeurs de taxis : déterminants de l’exposition et impact sur la santé respiratoire ”. In collaboration with Isabelle Momas, Laboratoire EA4064, Epidémiologie environnementale : impact sanitaire des
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pollutions Faculté de Pharmacie- Université Paris Descartes-Doctorant : Melissa Hachem, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon
3- November 2018-Current: Co-director “Mésusage des antibiotiques dans le traitement des infections respiratoires au Liban et conséquences sur le profil de résistance des germes impliqués ”. In collaboration with Patrick Maison, direction de la surveillance medicamenteuse-ANSM-Université Paris Est. Doctorant : Sally Yaacoub
PhD Jury participation 1- July 2019: PhD jury examiner. La Place de l’Infirmière dans la Juste Prescription des Antibiotiques en Etablissements Gériatriques. Taghrid Chaaban. Université Paris 13. 2- Avril 2019 : PhD jury reporter. Epidemiology of Cardiovascular disease and associated risk factors in Gaza Strip- Palestine. Amal Jamee Shahwan. University of Limoges. 3- December 2018 : PhD jury examiner. Etude médico-économique de la prise en charge des accidents vasculaires cérébraux au Liban : coûts de la maladie, mortalité, qualité de vie Rachelle Abdo, co- tutelle Lebanese university Doctoral School of Sciences and Technologies, Lebanon. 4- May 2018: PhD jury examiner. Wheezing phenotypes and risk factors in early life. Souheil Hallit, co- direction, Collège des écoles doctorales, Université de Bordeaux, France. 5- September 2017: PhD jury examiner. Waterpipe and Cigarette Tobacco Smoking: Effects on Pulmonary and Cardiovascular Functions and Acceptability of Shocking Pictorial Warnings in Lebanon. In collaboration with Isabelle Godin, Ecole de Santé Publique, Université Libre de Bruxelles. Doctorante : Nelly Layoun, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon. 6- April 2016: PhD Jury President. Chronic Obstructive Pulmonary Disease and asthma: a case-control study for measurement of effect biomarkers”. In collaboration with Rachelle Nadif, Medical School of Creteil-Hôpital Henri Mondor, Paris XII University, France. Doctorant : Zeina Akiki, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon. 7- March 2016: PhD Jury Examiner. “Cardiovascular diseases in Lebanon: prevalence, risk factors and management”. In collaboration with Athul Pathak, Université Paul Sabatier, Toulouse, France. Doctorant: Rouba-Karen Zeidan. 8- January 2016: PhD jury President. « Pollution and cardiovascular diseases: data from Lebanon ». In collaboration with Alain Leveque, Ecole de Santé Publique, Université Libre de Bruxelles. Doctorant : Zeina Nasser, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon 9- December 2015: PhD jury President« Nutrition, asthma and allergies in children ». In collaboration with Chantal Raherison, Université Victor Segalen, Bordeaux2, France. Doctorant : Danielle Saadeh, co-tutelle Lebanese University, Doctoral School of Sciences 10- October 2011-November 2015: Co-Director: « Cerebrovascular accidents in Lebanon : prevalence, incidence and risk factors ». In collaboration with Hassan Husseiny, Neurology service, Hôpital Henri Mondor – Université Paris XII. Doctorant : Nathalie Lahoud, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon. 11- December 2015: PhD jury President: « Association between obesity and stress in the Lebanese population ». In collaboration with Isabelle Godin, Ecole de Santé Publique, Université Libre de
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Bruxelles. Doctorante : Linda Abou Abbass, co-tutelle Lebanese University, Doctoral School of Sciences and Technologies, Lebanon.
Education
May 2014: University Certificate in " Systematic Review in health Policy: From Scoping the literature to Synthesizing the evidence" .American University of Beirut, Faculty of Medicine and health sciences.
2012 : TRAINING COURSES: “Pubmed, Zotero, Embase, Cochrane”: Bibliothèque Interuniversitaires de santé, Paris, France
Sep 2009-Sep 2012: POSTDOCTORAL RESEARCH POSITION Working on PNDS (Plan National de diagnostic et de soin) – International guidelines for diagnosis and care project for Huntington’s Disease with the collaboration of the “Haute Autorité de Santé Française” and the European Huntington Disease Network (EHDN) and the Cure Huntington's Disease Initiative (CHDI). I work as the project manager at the INSERM U955 (Institut National de la Santé et de la Recherche Médicale), Team I. Responsibilities Include: Initiate PNDS (methodology, collecting, selecting and scoring data) Writing the first draft conclusions for international recommendations Preparing and proposing a computerized pool for scoring the draft of recommendation Organization, implementation and management of meeting between different committees
2006-2009: PhD IN PHARMACOLOGY, “Université de Paris XII-Henri Mondor Teaching Hospital-Paris- France” Thesis Title: Neuroendocrine alterations in Huntington’s disease: clinical consequences and therapeutic implications. (with high distinction) Scholarship from the Henri Mondor Teaching Hospital-Paris-France Brief Synopsis of Research: Huntington’s disease (HD) is a neurodegenerative CAG triplet repeat disorder. It is clinically characterized by anxiety, depression, weight loss, chorea and dementia. Neuropathological changes include neuronal dysfunction, protein aggregates and cell death in the cerebral cortex, the striatum and the hypothalamus. The pathophysiological processes leading to the neurodegeneration and to the symptoms of HD remain unidentified and current hypothesis do not explain the intra-and interindividual heterogeneity of the evolution of these symptoms. Thus, disease progression in patients remains difficult or impossible to predict. My current research centres around hormonal disorders and their influence and role on the progression and possibly on the pathophysiology of the disease.
2005-2006: Interuniversity Diploma of Statistics Applied to Medicine (CESAM) – Paris VI University, France.
2004-2005: MASTER II IN CLINICAL PHARMACOLOGY, Paris VI University, Pierre et Marie Curie, Paris , France
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2001-2002: MASTER I IN MEDICAL AND BIOLOGICAL SCIENCES, Saint Joseph University, Beirut, Lebanon
1999-2000: Doctor of Pharmacy at the Lebanese University, Faculty of Pharmacy. Thesis subject: “Comparative study of Fluoroquinolones” Director: Dr Jacques Mokhbat.
1995-1999: BS in Pharmacy at the Lebanese University, Faculty of Pharmacy.
Publications
1- Nadine Saleh, Stéphane Moutereau, Alexandra Durr, Pierre Krystkowiak, Jean-Philippe Azulay, ChristineTranchant, Emmanuel Broussolle, Françoise Morin, Anne-Catherine Bachoud-Lévi, Patrick Maison. Neuroendocrine disturbances in Huntington's disease. Plos one2009;4(3):e4962 2- Nadine Saleh , Stéphane Moutereau , Jean-Philippe Azulay , Christophe Verny , Pierre Krystkowiak , Christine Tranchant , Nasser El Hawajri, Anne-Catherine Bachoud-Lévi, Patrick Maison. High insulinlike growth factor I is associated with cognitive decline in Huntington disease. Neurology. 2010 Jul 6;75(1):57-63 3- AI Tropeano, N Saleh, I Macquin-Mavier, P Maison. Do antihypertensive drugs improve Intima Media Thickness? A Meta-Analysis of randomized controlled trials. Fundam Clin Pharmacol. 2010 Jun 22 4- Linda Salem, Nadine Saleh, Katia Youssov, Audrey Olivier,Perrine Charles, Clarisse Scherer, Christophe Verny, Anne-Catherine Bachoud-Levi, Patrick Maison. The most appropriate primary outcomes to design clinical trials on Huntington’s disease: meta-analyses of cohort studies and randomized placebo-controlled trials. Fundamental & Clinical Pharmacology.2013 5- Cheaito L, Azizi S, Saleh N, Salameh P. Assessment of self medication in population buying antibiotics in pharmacies: a pilot study from Beirut and its suburbs. International Journal of Public Health, 2013 6- El Zoghbi M, Boulos C, El Hajje A, Saleh N, Awada S, Rachidi S, Bawab W, Salameh P. Association between cognitive function and nutritional status in elderly: a cross-sectional study in three institutions of Beirut – Lebanon. Geriatric Mental Health Care, 2013. 7- Aoun J, Saleh N, Waked M, Salamé J, Salameh P. Lung cancer correlates in Lebanese adults: a pilot case-control study. Journal of Epidemiology & Global Health, 2013. 8- Rachidi S, Awada S, Al-Hajje A, Bawab W, Zein S, Saleh N, Salameh P. Risky exposures during pregnancy: a pilot study from Lebanese mothers. Drug, Healthcare, and Patient Safety, 2013; 5: 123- 31. 9- Farah R, Lahoud N, Salameh P, Saleh N. Dispensing antibiotics by Lebanese pharmacists: a higher and lower socio-economic levels comparison. Journal of Infection and Public Health, 2014 10- Salameh P, Karaki C, Awada S, Rachidi S, El Hajje A, Bawab W, Saleh N, Waked M. Asthme et pollution: une étude pilote chez des adolescents Libanais scolarisés. Revue des Maladies respiratoires, 2014. Accepted, under press.
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11- Layoun N, Saleh N, Barbour B, Awada S, Rachidi S, El Hajje A, Bawab W, Waked M, Salameh P. Waterpipe effects on pulmonary function and cardiovascular indices: a comparison to cigarette smoking in real life situation. Inhalation Toxicology, 2014; 26(10):620-627. 12- El Zoghbi M, Boulos C, Awada S, Rachidi S, Al-Hajje A, Bawab W, Saleh N, Salameh P. Prevalence of malnutrition and its correlates in older adults living in long stay institutions situated in Beirut. Journal of research in Health Sciences, 2014; 14(1): 11-17. 13- Salameh P, Rachidi S, Al-Hajje A, Awada S, Chouaib K, Saleh N, Bawab W. Consommation de substances psychoactives des étudiants universitaires Libanais : prévalence, facteurs associés et protecteurs. Eastern Mediterranean Health Journal, 2014 14- F Drouby,P Salameh, M Cherfan and N Saleh. Evaluation of Aspirin Use for Primary and Secondary Prevention of Cardiovascular Diseases among Lebanese Population. Journal of Pharmacy and Pharmacology.3:(2015) 569-590 15- N Lahoud, N Saleh, P Salameh, H Hosseini Prevalence of Lebanese stroke survivors: A comparative pilot study. Journal of Epidemiology and Global Health. 2015 16- P Salameh, S Rachidi, A Al-Hajje, S Awada, K Chouaib, N Saleh , W Bawab. Substance use among Lebanese university students: Prevalence and associated factors. Eastern Mediterranean health journal. 2015 17- Bou Assi Samah, Slaibi Youssef, Salameh Pascale, Saleh Nadine. Development of a scoring system to measure drug compliance among patients with chronic diseases in Lebanon. Journal of Hypertension. 2015 18- Nadine Saleh, Sanaa Awada , Rana Awwad, Sahar Jibai, Chadi Arfoul, Liliana Zaiter , Wissam Dib, Pascale Salameh. Evaluation of antibiotic prescription in the Lebanese community: a pilot study. Epidemiology and Infection. 2015 19- Elias Chelala, Nadine Saleh, Ali Dirani, Ali Fadlallah, Patrick Baz, Elise Slim, Georges Halaby, Riad Bejjani. Dépistage de la rétinopathie et de la maculopathie diabétique au Liban par Rétinographie et par SD-OCT: Intérêt de la Télémédecine. Lebanese Medical Journal, 2015 20- Salem L, Saleh N, Désaméricq G, Youssov K, Dolbeau G, Cleret L, Bourhis ML, Azulay JP, Krystkowiak P, Verny C, Morin F, Moutereau S; French Huntington Study Group., Bachoud-Lévi AC, Maison P. Insulin-Like Growth Factor-1 but Not Insulin Predicts Cognitive Decline in Huntington's Disease. Plos One. 2016 21- Désaméricq G, Youssov K, Charles P, Saleh N, Olivier A, Sherer-Gagou C, Verny C; multidisciplinary working group., Bachoud-Lévi AC. Guidelines for clinical pharmacological practices in Huntington's disease. Journal of neurology. 2016. 22- Nathalie L, Pascale S, Nadine S, Hassan H. Reply to the commentary of Dr. Josué Lily Vidal: Paper: Prevalence of Lebanese stroke survivors: A comparative pilot study. J Epidemiol Glob Health. 2016 Dec;6(4):329–30. 4 23- P Salameh and N Saleh. Knowledge, Attitudes, Believes and Practice regarding antibacterial resistance and appropriate use of ATBs in EMRO region: A systematic review. WHO 2016 24- Zeitouny M, Feghali M, Nasr A, Abou Samra P, Saleh N, Bourgeois D, Farge P. SoproLife system: an accurate diagnosis enhancer. The scientific world Journal. 2017
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25- Lahoud N, Abbas M, Saleh N, Salameh P, Hosseini H and Gebeily. A retrospective analysis of 254 acute stroke cases admitted to two university hospitals in Beirut: Classification and associated factors. Functional Neurology. 2017 26- Bou Serhal R, Salameh P, Wakim N, Issa C, Kassem B, Abou Jaoude L, Saleh N. A new Lebanese Medication Adherence Scale: Validation in Lebanese Hypertensive Adults. International journal of hypertension. 2018 27- Lahoud N, Gebeily S, Salameh P, Saleh N, Abbas M, Hosseini H: Care and discharge outcome of acute stroke in Lebanon: A hospital-based study. Journal of nervous and mental health.2018 28- Hallit S, Zahreddine L, Saleh N, Shakaroun S, Lahoud N. Practice of parents and pharmacists regarding antibiotics use in pediatrics: a 2017 cross sectional study in Lebanese community pharmacies. Journal of evaluation and the health professions. 2018 29- Mansour H, Feghali M, Saleh N, Zeitouny M. Knowledge, Practice and Attitudes regarding Antibiotics use among Lebanese dentists. Journal of Pharmacy Practice. 2018 30- Ghaddar F, Salameh P, Saleh N, Farhat F, Chahine R, Lahoud N. Hleyhel M, Zeidan RK. Non cardiac Lebanese hospitalized adult patients’ awareness of their coronary artery disease risk factors. Journal of epidemiology and global health. 2018 31- Akel Marwan, Dabbous Mariam, Sakr Fouad, Safwan Jihan, Cherfan Michelle, Rahal Mohamad, Salameh Pascale, Shrayteh Zeina, Saleh Nadine. Evaluation of the practice of constipation management in the Lebanese community pharmacies". Journal of Pharmacy and Pharmacology. 2018 32- Yaacoub S, Lahoud N, Francis N, Rahme D, Murr T, Maison P and Saleh N. Antibiotic prescribing rate in Lebanese community pharmacies: A nation-wide patient simulated study of acute bacterial rhinosinusitis. Journal of Epidemiology and Global Health. 2019
33- Melissa Hachem, Nadine Saleh, Isabelle Momas, Lynda Bensefa-Colas. Exposure to traffic air pollutants in taxicabs and acute adverse respiratory effects: a systematic review. Journal of Science of the Total Environment. 2019 34- Philippa Boulle, AlbaneSibourd-Baudry, Éimhín Ansbro, Nadine Saleh, Rouba Karen Zeidan, Pablo Perel. Cardiovascular Disease among Syrian refugees: a descriptive study of patients in two Médecins Sans Frontières clinics in northern Lebanon. Conflict and Health journal. 2019 35- Sally Yaacoub, Nathalie Lahoud, Deema Rahme, Nicole Francis, Nadine Saleh, Patrick Maison. Antibiotic Prescribing in Lebanese Community Pharmacies using a Patient-Simulated Case of Acute Uncomplicated Cystitis. Pharmacy Practice. 2019
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Articles in preparation/submitted
1) Lahoud N, Rizk R, Baaklini M, Zeidan RK, Hleyhel M, Maison M and Saleh N. Antibiotic consumption trends in Lebanon: a review of a 13 year period (2004-2016). Submitted to journal of clinical infectious disease 2) Lahoud N, Chehabeddine N, Noujeim Z, Zeidan R, Masion Patrick, Saleh N. The use of antibiotics in Lebanese dental practice: analysis of prescriptions.
3) Lahoud N, Shehabeddine N, Njeim Z,Toum S,Maison P, Saleh N. Rational antibiotic prescribing in dental practice in Lebanon. In preparation.
4) Usage of PPI in Beirut.
5) Droubi Fida, cherfan Michele, Salameh Pascale, Saleh Nadine. Evaluation of Aspirin Use for Primary and Secondary Prevention of Cardiovascular Diseases among Lebanese Population: Safety and adherence data. Submitted to pharmacy prcatice 6) Hajar Samaha, Rouba Karen Zeidan, Nadine Saleh, Mira Hleyhel, Natalie Lahoud. A national survey on the knowledge, attitudes, and practices of Lebanese women towards oral contraceptives use.
8) Knowledge, Attitudes and Practices of Syrian Refugees towards Antibiotic Use in Lebanon. In preparation
9) Knowledge, attitudes and practices of a sample of Lebanese nurses towards antibiotic usage. In preparation
10) Validation of the Lebanese Medication Adherence Scale among patients with hypothyroidism and evaluation of factors associated with adherence.
Languages
English, French and Arabic
Practical Knowledge
Different software concerning medicine, drugs, statistics, epidemiology: Medline, Embase , Epiinfo, SPSS, SAS, Endnote, zotero, Revman
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Affiliations
- Member of the Lebanese Academic Pharmacist Society, since January 2014. - Member of the Lebanese Order of Pharmacists since 2000. - Member of the Pharmacy Lebanese Colloquium Comity since 2014 - Member of the Clinical and Epidemiological Research team since 2013 - Member of the Pharmaco-epidemiology Unit – CERIPH – Faculty of Public Health – Lebanese University since 2015.
References
Available upon request.
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