Air Sanitizer

TM Air/Q 1200A

User Guide

Original Instructions

I. Introduction: About Air/Q™ 1200A witharia Air Sanitizer...... 1 II. Safety Precautions...... 3 A. Appliance Precautions B. aria™ Precautions III. Appliance and Controls...... 4 IV. General Maintenance...... 5 A. Changing the Cartridge B. O-ring Replacement C. Air Filter Replacement D. Battery Replacement V. Commissioning the Air/Q 1200...... 6 A. Unit Programming B. Directions for Use C. Adjusting for Optimal Performance VI. Installation: Diffusion via Direct Indoor Fan...... 9 A. Installation Kits B. Pre-Installation Checklist C. Appliance Positioning D. Appliance Installation E. Diffusion Fan Installation VII. Installation: Diffusion via HVAC System...... 14 A. Installation Kits B. Pre-Installation Checklist C. Appliance Positioning D. Appliance Installation E. Injector Tube Installation VIII. Troubleshooting...... 19 IX. Frequently Asked Questions...... 20 IX. General Care and Customer Support...... 26 X. Specifications...... 26

Air/Q 1200A User Guide © 2010 Prolitec, Inc. Introduction I. Introduction: About Air/Q 1200A witharia ™ Air Sanitizer The aria™ Infection Control System is an “always-on” air sanitizer which, when used as directed, will continuously and significantly reduce the numbers of viable, living bacteria in the treated space.1 The aria™ system is suitable for use in any interior space where the transmission of contagion by the airborne pathway is considered a risk such as assisted living communities, skilled nursing facilities, clinics, hospitals, classrooms, cruise ships and any interior space with a group of people in close proximity. Airborne bacteria can be generated by coughing, sneezing or aerosolizing bacteria which has settled on surfaces.

aria™ does not replace the need for best practices in infection control such as frequent hand washing, surface cleaning and the like. aria™ is a 24/7 adjunct to these practices. aria ™ works continuously to kill bacteria in the air by generating and maintaining a steady concentration of human-safe and invisible glycol vapor. Use of aria™ reduces but does not eliminate the risk of infection.

The Air/Q 1200A is managed by an on-board computer that is fully programmable for intensity to match space sizes from 1,800 to 150,000 cubic feet per appliance. Multiple appliances can work together on the same or multiple CFUs to treat the air in the same spaces served by the HVAC. Multiple appliances can work together in the same space. One appliance is required for each 150,000 cubic feet.

The Air/Q 1200A works by generating ultra fine, ultra-light droplets approximately 1 micrometer (µm) in diameter. By comparison, a droplet from a typical pressurized aerosol spray can is 50 microns (50000 nanometers) in diameter or 50 times larger than an Air/Q 1200A droplet. In terms of weight and volume of liquid, the comparison is even more dramatic. A 50-micron aerosol droplet is 125,000 times heavier than a 1 µm Air/Q droplet.2 (See also Table 1 below.) This tiny Air/Q droplet offers many performance benefits over a conventional aerosol including: completely uniform distribution of the treatment agent; 50 times more exposed surface area allowing more efficient conversion of the active ingredient in aria™ into the vapor required for air sanitizing; and the absence of any liquid deposits on surfaces such as the interior surfaces in an HVAC system.

The Air/Q 1200A Guide is packed with important information that will help the users, installers and service engineers optimize the performance of this modern air treatment system. We encourage you to read it carefully.

1 “There is considerable evidence that glycol vapors produce significant decreases in numbers of viable airborne bacteria under relatively wide conditions of relative humidity and temperature when properly and continuously dispensed by a vaporizing device [such as the Prolitec Air/Q 1200A] so as to maintain suitable concentrations in the air of enclosed spaces.” EPA Website accessed 10 May 2010: “DIS/TSS-11 / Sep. 3, 1980 EFFICACY DATA AND LABELING REQUIREMENTS: Air Sanitizers” (EPA Home >> Pesticides >> Science and Policy >> Policy and Guidance >> Antimicrobial Science Policies >> Air Sanitizers; http://www.epa.gov/oppad001/ dis_tss_docs/dis-11.htm) 2 This value is based on spherical volumes of two droplets of identical density

Table 1. Prolitec Air/Q Technology vs. Aerosol Spray Can Technology

Parameter Prolitec Air/Q Technology Aerosol Spray Can

Droplet Diameter, µm 1 50

Volume per Droplet, µm3 0.52 65,450

Surface Area per Droplet, µm2 3 7,854

Relative Volume per Droplet 1 125,000

Relative Weight per Droplet 1 125,000

Number of Droplets per Equivalent Volume 125,000 1

Surface Area/Volume, µm-1 6.00 0.12

Relative Surface Area per Volume 50 1

Prolitec Aerobiology and Infection Control ©Prolitec Inc 2009, 2010

A. Air/Q 1200A Appliance Precautions: 1. DO NOT position Air/Q within the reach of young children or pets.

2. The appliance must be operated in an upright or vertical position and firmly attached to a vertical surface such as a wall or a duct.

3. The appliance should NOT be used with the door in the open position. The door is opened only to perform a cartridge or program change.

4. NEVER put your nose to the output of Air/Q 1200. Within 12 inches of the output, the fragrance is highly concentrated. The improper inhalation of high concentrations of fragrance may cause irritation including watery eyes, headache, cough and upper respiratory discomfort.

5. The appliance is built to be plugged into an 110VAC or 220VAC power outlet. Must be used only with the approved and included power supply. The UL and CE compliant power supply converts power to 12V DC to power the appliance.

6. Unplug before cleaning.

For online safety instructions, visit www.prolitec.com/manuals/manuals.htm

B. aria™ Cautions - HAZARDS TO HUMANS AND DOMESTIC ANIMALS 1. CAUTION: If the cartridge leaks or spills, the liquid product causes moderate eye irritation. Avoid contact with eyes or clothing. Wash thoroughly with soap and water after handling the liquid and before eating, drinking, chewing gum or using tobacco.

2. FIRST AID If the liquid gets in the eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-800-222- 1222 for emergency medical treatment information

3. PHYSICAL AND CHEMICAL HAZARDS: Do not use or store near heat or open flame.

4. Read the aria™ Label, the Consumer Product Safety Information Sheet and the Material Safety Data Sheet found in the Appendices of this manual and enclosed with each shipment of Cartridges. Ensure that these information sheets are available for review by employees.

Injector Hose

Control Display Hose Clamp

Hose Connector

Air Nozzle Control Buttons

Program Air Filter Selector

Recyclable Cartridge

Power Cord

Battery Tab

A. Changing the Cartridge 1. Unlatch and open the door to access the cartridge: The door should be opened only to perform a cartridge or programming change. When in use, the door must be closed.

2. Press POWER button to turn appliance OFF.

3. Remove air nozzle (located on the side of the cartridge head) by rotating 90 degrees and pulling towards you. (See Picture 1 below)

4. Detach Injector hose and hose connector from the cartridge output port (located on the top of the cartridge head). This is done by unscrewing the hose connector from the cartridge output port and pulling out.

5. Remove cartridge from appliance enclosure.

6. Install new cartridge, place and tighten hose connector firmly on cartridge output port.

7. Insert air nozzle and rotate the handle 90 degrees until secured (by stem retaining tab on cartridge head). (See Picture 2 below)

8. Turn appliance ON. Verify that the plume is not escaping inside the appliance and that all connections are tight. Close the door when complete.

Picture 1 Picture 2

Cartridge Retaining Tab

B. O-Ring Replacement – each year or as needed 1. Replace the air nozzle’s 3 amber O-rings (Part number 8211) if worn or damaged. Replace as needed and/or each year for preventative maintenance.

2. If there is any fragrance that leaks during the cartridge installation, clean it carefully with a paper towel and some ethanol or another alcohol.

C. Air Filter – every 6 months or as needed Replace air filter (part number 10417) if dirty. If any dust has gathered inside the unit, remove it with a damp paper towel.

D. Battery Replacement – approx. every 2 years: (requires 3 Volt CR2032 Lithium Battery, part number 8111)

1. Unlatch and open the door to access the enclosure.

2. Using a pair of tweezers or needle-nose pliers, remove battery from the center opening of the oval grommet. The grommet is located on the front of the blue bracket below the operating buttons.

3. Insert the new CR2032 battery. The positive side of the battery should face your right while looking at the front of the appliance. The battery will have a + or – marking on a side.

V. Commissioning the Air/Q 1200A

A. Unit Programming

1. Unlock and open the door. 2. Turn on the power by pressing the ON/OFF button in the upper left corner of the control panel. 3. Set the Clock. • Turn the dial to Set Clock. The day-of-the-week icon will blink. • Adjust the day forward or backward using the +/– buttons on the right side of the control panel. AM or PM is indicated on the lower right side of the time digits. • Press the Set button on the lower left corner of the LCD display. The time will blink. • Adjust the time forward or backward using the +/– buttons on the right side of the control panel. AM or PM is indicated on the lower right side of the time digits.

4. Turn the dial to Run 24/7. 5. Set the Rate to the level recommend in Cell B11 of the aria™ CSP Calculator (See Number of Appliances and Settings.) 6. Make sure the power is on. The blue light will show through the button. 7. Close and lock the door, storing the key in a known place.

B. Directions for Use

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. This product is to be used with a compatible Prolitec appliance, either the Air/Q 550A or the Air/Q 1200A. This User Guide concerns itself with the Air/Q 1200A programmed for aria™.

HOW TO OPERATE: To continuously sanitize the air in an interior space use the compatible Prolitec appliance to dispense the vapor of aria™ into the air. Here are the steps: 1. Determine the size of the space to be treated in cubic feet or meters - Width x Length x Ceiling height and insert that value into cell B5 of the CSP Calculator. Check that it is the latest version of the Calculator.

2. Insert your desired service cycle in months and insert that value into cell B6. Fractions of a month will work, e.g. 1.5 months is about 6 weeks. Check the Estimated Service Days in Cell B12.

3. Install the number of appliances suggested in Cell B9 in accordance with this User Guide.

4. Adjust the Rate setting to the value in cell B11.

5. Set the dial to 24/7 operation.

6. Install the number of appliances recommended by the sizing algorithm.

7. Install the Cartridges of aria™ in the appliances.

8. Power on each appliance, set the dial to 24/7 operation.

9. Set the intensity to the level recommended by the sizing algorithm.

10. Replace cartridges as needed.

C. Adjusting for Optimal Performance

Optimal efficacy is obtained when the amount of aria™ in the air is at or just below the level at which condensation will occur on a glass or mirrored surface. Varying airflow conditions in a space including the number of air changes per hour affects the amount ofaria ™ vapor in the air. Periodic incremental adjustments in the Air/Q 1200A setting are recommended to ensure optimal aria™ concentrations. After an adjustment is made it is recommended that 24 hours be allowed for equilibration before further adjustment.

1. Check the system after 30 days of operation. If there is no residue on the detection mirror, increase the setting or add additional appliances.

2. On the first cartridge change (about 30 days later), carefully check for residue again. If there is still no residue, increase the setting by 5 . If there is residue, decrease the setting by 5.

3. If by the second cartridge change, you still have not detected residue, increase the setting by 5. If there is residue, decrease setting by 5.

4. Follow this procedure until residue is detected after 30 days of operation at the setting. It there is residue, decrease by 5 to the optimal setting. If there is no residue even at top settings of 50, you will need additional appliances.

Hint: The installation kit contains a small adhesive-backed mirror, which should be attached to the side of a wall-mounted appliance or anywhere in the space if it is treated through the HVAC system.

Estimated aria™ Cartridge Life (Hours) Setting Air/Q 510 Air/Q 1000 Air/Q 530 Air/Q 1200 50 175 417 40 219 521 30 292 694 20 438 1,042 10 875 2,083

A. Installation Kits

• Installation Kit for Appliance (included) 1. One (1) Air/Q 1200A appliance (not pictured) with: 2. Four (4) dry wall anchors for mounting in drywall 3. Four (4) lead anchors for mounting in concrete 4. Four (4) screws and (4) washers for mounting in drywall and concrete 5. Four (4) #10 self-tapping sheet metal screws for mounting in sheet metal 6. Five (5) feet of large cable raceway for power cable 7. Hose connector and hose clamp (for cartridge attachment) 8. One adhesive-backed mirror

4 2 3

5 6

© 2010 Prolitec, Inc. Air/Q 1200A User Guide 9 Installation: Diffusion via Direct Indoor Fan • Installation Kit for Fan (included) 1. One (1) Prolitec Diffusion fan and cable for direct indoor diffusion 2. Three (3) dry wall anchors for mounting fan onto dry wall 3. Three (3) lead anchors for mounting in concrete 4. Three (3) screws for mounting in drywall and concrete 5. Five (5) feet of small cable raceway for fan cable 6. Five (5) feet of black 5/8th-inch OD injector hose

2 1

10 Air/Q 1200A User Guide © 2010 Prolitec, Inc. Installation: Diffusion via Direct Indoor Fan • Installation Kit for Fan (included) B. Pre-installation Checklist (should be completed before install date) 1. One (1) Prolitec Diffusion fan and cable for direct indoor diffusion 2. Three (3) dry wall anchors for mounting fan onto dry wall 1. Confirm the area to be targeted for air treatment. 3. Three (3) lead anchors for mounting in concrete 4. Three (3) screws for mounting in drywall and concrete 2. Confirm the general direction of ambient air flow in the area and position the machine so that the 5. Five (5) feet of small cable raceway for fan cable plume will be more evenly distributed and carried by the natural air flow. 6. Five (5) feet of black 5/8th-inch OD injector hose 3. Determine the number of machines required, which is the total cubic feet to be served divided by a maximum of 150,000.

2 4. Based on 2 above, determine the wall positions for installation, keeping in mind that the Appliance 1 requires 110/220V AC.

C. Appliance Positioning

It is important to find a location that is easily accessible for service and cartridge refills.

D. Appliance Installation 6 Waterproof Collar 1. The appliance is wall-mounted. Place the appliance onto the desired location on the wall and ensure that it is level.

2. Fasten the appliance to the wall using the necessary 5 anchors, screws and washers provided.

3. Open the enclosure door and unscrew the aluminum cap of the waterproof collar located on top of the appliance enclosure. Remove and set aside the grommet. (Fig. 1)

4. Assemble hose and hose connector together (Fig. 2) Be 4 sure to leave approximately 1/8 of an inch clearance between the top of the cartridge hose connector and the Fig. 1 end of the hose. Then secure with clamp, ensuring that 3 the hose connector is still free to rotate. Hose Connector Clamp 5. From the inside of the enclosure, slide hose assembly upward through to the waterproof collar. (Fig. 1)

6. Lube the inside of the grommet if needed to allow the Injector hose to easily slide through. Leave approximately 2 inches of hose length inside the appliance to provide enough play when Leave 1/8” clearance replacing the cartridge. Tighten aluminum cap of waterproof Fig. 2 collar to ensure a watertight seal.

7. Connect the power cord to a junction box or connect AC plug to a nearby outlet.

E. Diffusion Fan Installation

Fig. 3 Fig. 4 Fig. 5 Fig. 6

1. The Diffusion Fan is positioned directly above the appliance hose output port located on the top left of the appliance but no more than 4-1/2 feet above it. (Fig. 3)

2. Use the Diffusion Fan assembly as a template to mark the location of the mounting holes. (Fig. 4)

3. For installation on drywall, drill the 3 anchors into drywall and install the 3 screws to secure the Diffusion Director fan to the wall. Use the metal screws provided for installation on sheet metal or appropriate fastening hardware for other wall surfaces. (Figs. 5 & 6)

4. Verify cable connection with Diffusion Fan. (Fig. 7)

5. Measure the length of cable raceway needed and cut to length using a pair of scissors or a cutting blade. (Fig. 8) Fold into an “L” shape and peel off liner. (Fig. 9) Fasten adhesive side to the wall between appliance and Diffusion Fan assembly.

Fig. 7

Fig. 8 Fig. 9 Fig. 10 Fig. 11

6. Run Diffusion Fan cable inside the raceway, (Fig. 10) fold the raceway into a square and snap the raceway cover closed. (Fig. 11) If needed, use a flat-head screw driver to push in the side wall of the cable raceway.

Fig. 12 Fig. 13 Fig. 14

7. Insert cable connector into jack located on the right side of the appliance. (Fig. 12)

8. Extend the hose from appliance toward the Diffusion Fan hose barb, cut to proper length (Fig. 13) and secure to the hose barb of the Diffusion Fan assembly. (Fig. 14)

9. Turn the APPLIANCE on and verify that a plume is produced.

A. Installation Kits • Installation Kit for Appliance (included) 1. One (1) Air/Q 1200A appliance (not pictured) with: 2. Four (4) dry wall anchors for mounting in drywall 3. Four (4) lead anchors for mounting in concrete 4. Four (4) screws and (4) washers for mounting in drywall and concrete 5. Four (4) #10 self-tapping sheet metal screws for mounting in sheet metal 6. Five (5) feet of large cable raceway for power cable 7. Hose connector and hose clamp (for cartridge attachment) 8. One adhesive-backed mirror

4 2 3

5 6

• Installation Kit for HVAC System Diffusion (included) 1. One (1) Prolitec injector tube for diffusion into HVAC system 2. Three (3) #10 self-tapping sheet-metal screws for mounting the injector tube in sheet metal 3. Five (5) feet of 5/8 inch OD injector hose

1 3

B. HVAC Pre-installation Checklist This checklist should be completed before the install date.

1. Confirm the area to be targeted for air treatment.

2. Determine the Air Handling Unit or duct that serves the target area.

3. Make sure the AHU does not use an open gas flame.

4. Find and mark the optimal insertion point for the Injector Tube. (See “Appliance Positioning” below)

5. Find and mark the exact location for placement of the appliance. (See “Appliance Positioning” below)

6. Note the distance between the insertion point and the proposed appliance location. (NEVER MORE THAN 5 FEET and there should NEVER be a LOW POINT in the hose run.)

7. Determine and mark the location for the 110 or 220V AC power outlet (NEVER DIRECTLY BELOW THE appliance).

C. Appliance Positioning It is important to find an insertion point where the plume output will be smoothly drawn into and mixed with the airflow. This usually means those parts of the AHU where the static pressure is negative. Ideal locations include:

• Before the supply fan with injection through the wall of the AHU. Positioning immediately before the fan and after the coils if possible or in the mixed air chamber. • Behind the blower with the whole appliance mounted inside the AHU in the mixed air chamber. • Outside the AHU in the Supply air duct.

Best practice when installing in an AHU is to place the injector tube after the heating and cooling coils. If this is not possible, the Plume output can pass over hot water, steam, chilled water, and DX coils.

Open gas flames should absolutely be avoided. If installation must be over gas heated coils or open gas flames, contact Prolitec Technical Support.

The best location for the Appliance is below the injector tube (Fig. 15). The injector hose should be run upward as short a distance as possible and NEVER MORE THAN 5 FEET. If an upward injector hose run is not possible, care should be taken support the hose to prevent sagging or any low spot in the run to avoid any possibility of condensation and liquid collection which will block the plume output. The injector hose is prone to stretching, so support points should be placed every 5 to 6 inches on horizontal runs. Give the hose a slight upward slant along its run (See Fig. 16). The hose must not be run horizontally. A strong tape (such as Venture tape) may be used to support short runs. The hose may be run through PVC pipe for longer distances.

Fig. 15

Injector Hose Injector Tube Power Junction Box

Air/Q 1200A

Fig. 16 CORRECT INCORRECT

D. Appliance Installation

1. The appliance is wall-mounted. Place the appliance onto the desired location on the wall or AHU and ensure that it is level.

2. Fasten the appliance to the wall or AHU using necessary screws.

3. Connect the power cord to a junction box or attach an AC plug to the cord and connect to a nearby outlet. Open the enclosure door and unscrew the aluminum cap of the waterproof collar located on top of the appliance enclosure. Remove and set aside the grommet (Fig. 1 on p. 11).

4. Assemble hose and hose connector together (Fig. 2 on p. 11). Be sure to leave approximately 1/8 of an inch clearance between the top of the cartridge hose connector and the end of the hose. Then secure with clamp, ensuring that the hose connector is still free to rotate.

5. From the inside of the enclosure, slide hose assembly upward through to the waterproof collar (Fig. 1 on p. 11).

6. Lube the inside of the grommet if needed to allow the Injector hose to easily slide through. Leave approximately 2 inches of hose length inside the appliance to provide enough play when replacing the cartridge. Tighten aluminum cap of waterproof collar to ensure a watertight seal.

E. Injector Tube Installation The injector tube is installed directly into the AHU or ductwork. Its orientation can be adjusted relative to airflow.

• For installations into the negative/suction side of the AHU fan, orient the tube with the elbow pointed upwards, so that any plume condensation will sip back in the tube.

• For installations after the supply fan, such as in a supply duct, it is necessary to configure and orient the Injector Tube to obtain a good aspiration of the output into the air stream. The injector tube should be pointed in the direction of the airflow and inclined approximately 45o upward. Turbulence in the airflow

can prevent even aspiration of the plume. It is best to place the tube in a straight section of duct, and far away from any turns, branches, or cross-section changes as practical, and not immediately after the supply fan.

1. At the insertion point, drill a hole using a ½” drill bit.

2. Insert the Injector Tube through the hole.

3. Find an orientation of the injector Tube that appears to produce a good draw of air into the end of the barb.

4. Fasten the flange using the three #10 sheet metal screws.

5. Turn the appliance on and verify that a plume is produced.

6. Before attaching the Injector hose to the injector, verify that the plume can flow easily through the injector. This can be done by placing the end of the hose ½ inch away from the injector and verifying that the plume is being drawn in (a flashlight will make the plume easier to see). If the plume does not rise into the hose, adjust the orientation of the Injector Tube until aspiration is achieved.

7. Attach the Injector hose onto the hose barb of the Injector Tube.

For Cartridge Installation – See “Changing the Cartridge” in the General Maintenance section.

Condition Causes Solutions

Power light off. The Appliance is not • Make sure the power connection is plugged in or the plug has operational. no power • Verify that the power button light is blue when pressed.

Unit does not start auto- Back-up battery not • Verify the protective yellow battery tab has matically after a power operational been removed. interruption. • Verify the battery is positioned with the positive side facing the right. • Replace the back-up battery.

Condensation is not The time required to If the Air/Q is operating normally, i.e., it is observed at the highest saturate the atmosphere not overheating, there are no changes in the aria™ setting. with aria™ is dependent sound of the unit, or other apparent signs of on many factors including mechanical failure, allow one week of continuous the size if the room, operation. If condensation is not observed air exchange rates, and after that time please contact your service materials that will absorb representative. aria™ such as bedding materials and paper.

When using aria™ there The output rate is too Lower the output rate in increments of 10 per is heavy condensation on high. day until the condensation disappears. After the my windows and mirrors condensation disappears, increase the setting by and/or there is a visible 5. After one day increase the setting by 1 if no fog in the room. condensation is visible or decrease the setting by 1 if condensation is visible. Periodic adjustment may be necessary.

The power light is on You are in an “OFF” period Simply wait a few minutes for the appliance to but the there is no output in the Timer cycle. cycle on. If the real problem is that the scent or you cannot hear the cannot be detected, increase the output rate as compressor in the instructed above. appliance.

Condition Causes Solutions

The power light is on and The output tube may be Remove the hose from the output tube leaving the compressor can be blocked. the Cartridge in place in the appliance. Turn the heard but no fragrance appliance on so you can hear the compressor. detected. Use a flashlight to observe the top of the output head for a plume of droplets. If you can see the plume then the blockage may be in the hose or the injector tube into the HVAC. Check these. If there is no plume something is blocking the output tube. Check and remove it.

The air intake may be Another method for clearing obstructions is, blocked. while the appliance compressor is running, block the output tube with a finger for 2 or 3 seconds and then open it by removing your finger.

The O-Rings on the stem Replace the O-Rings by removing the worn one that fits into the head may with a pointy tool and rolling on the new ones. be worn out and causing an air leak.

IX. Frequently Asked Questions

Do I need to treat the air 24/7?? Yes, the antimicrobial effect ofaria ™ requires maintaining continuous concentrations of at least 1 part per million in the air. What is aria™? aria™ is an EPA registered “always on” air sanitizer which operates automatically 24/7 to kill airborne bacteria in interior spaces and inside HVAC systems and thereby reduce the risk of infection by the airborne pathway. aria™ use the HVAC system; or its appliances may be wall or ceiling-mounted. A table-top unit us also available for rooms. The aria™ delivery system uses disposable cartridges of a human-safe liquid anti-microbial.

Where is aria™ effective? aria™ can be used as the basic infection control system or an adjunct/supplement to an existing infection control program in HOSPITALS, CLINICS & ACUTE CARE CENTERS; SURGERY CENTERS; ALTERNATE CARE FACILITIES; CANCER TREATEMENT CENTERS; DIALYSIS FACILITIES; SKILLED NURSING AND LONG-TERM CARE FACILITIES; ASSISTED LIVING FACILITIES; SCHOOLS and; any venue where facility-acquired infection transmission by the airborne pathway may be an issue. How does aria™ work? The aria™ system works by converting liquid-state glycols (such as triethylene glycol and propylene glycol) into controlled amounts of invisible vapor uniformly distributed throughout an interior space via the HVAC

system or directly from a table-top, wall or ceiling-mounted appliance. The aria™ system consists of patented computer-controlled vapor generators of various capacities; tamper-proof cartridges of the liquid antimicrobial; and devices and methods for monitoring the concentration of glycol vapor. The aria™ system is EPA-regis- tered1 and safe for continuous use in human-occupied spaces. What is the performance objective? What is the aria™ system supposed to do? The aria™ system is designed to …significantly reduce airborne bacteria under relatively wide conditions of relative humidity and temperature.”2 Is aria™ safe? Please read the Material Safety Data Sheet (MSDS). The U.S. Environmental Protection Agency (EPA) has deter- mined that the active ingredient in aria™ has no toxicity consequence for ingestion, skin contact and inhalation.3 The aria™ system complies with the workplace inhalation standards established by the US Department of Labor, Occupational Safety and Health Administration (OSHA),4 the American Congress and Governmental and Industrial Hygienists (“ACGIH”), and the State of California Environmental Protection Agency.5 The aria™ system produces no ozone and no known allergens. We have an infection control program. Why do I need aria™? aria™ can be an important adjunct to the core infection control program. It is intended to fill the gap in the infection control program between manual staff-dependent practices and mechanical air filtration systems. Virtually every aspect of a “best practices” infection control program is focused on surfaces and dependent on staff. aria™ is not. aria™ is automatic. aria™ is always on 24/7. aria™ targets a wide array of bacteria in the air to inactivate it before settling on surfaces.

Is there any third-party validation that the aria™ system actually works? According to the EPA registered label, “aria™, used as directed, operates as an air sanitizer.” An “air sanitizer” is defined by EPA as an antimicrobial which reduces the bacteria count to levels considered safe by public health codes and regulations.6 The EPA has also stated that “There is considerable evidence that glycol vapors produce significant decreases in numbers of viable airborne bacteria under relatively wide conditions of relative humidity and temperature when properly and continuously dispensed by a vaporizing device so as to maintain suitable concentrations in the air of enclosed spaces.”7 The aria™ system operates in the manner described here. Based on the scientific literature and our own expertise, we believe that suitable and continuously maintained concentrations of glycol vapor will be effective in reducing the airborne transmission of a diverse array of microorganisms. Is there any peer-reviewed research confirming the antimicrobial efficacy of aria™? Yes, the antimicrobial efficacy of the active in ingredient in aria™ - in the vapor form produced by the aria™ system – is the subject of several peer-reviewed research studies which can be readily accessed online in the professional literature searching for “triethylene glycol” or “air sanitizer.” How about surfaces? aria™ is unique as an antimicrobial in targeting a wide array of airborne micro-organisms as they are introduced by coughing, sneezing or some other source and before these bacteria are inhaled into the mucosa, circulated through the air handler or settle on surfaces. In this way aria™ supports the surface disinfection effort while directly filling the airborne gap in the infection control program. Prolitec is investigating the efficacy of aria™ on surfaces to produce data for consideration by the EPA.

© 2010 Prolitec, Inc. Air/Q 1200A User Guide 21 Frequently Asked Questions You do not claim that aria™ kills ALL bacteria and viruses. So why is aria™ needed? The battle against infection is a numbers game. The objective of an infection control program is to reduce the total numbers of bacteria to levels that the affected human immune systems can resist. aria™ significantly reduces bacteria levels and, therefore, can be reasonably considered to be an important contributor to the overall infection control program. Against what bacteria and viruses is glycol vapor effective? Peer reviewed research has shown efficacy for the vapor form of triethylene glycol against influenza virus (A/ PR/8/34 H1N1); Escherichia coli; Chlamydophila psittaci (cited as meningopneumonitis virus strain Cal 10 and psittacosis virus strain 6BC) and sittacosis viruses; Mycobacterium bovis (cited as tubercle bacilli (Ravenel bovine-type)); Serratia marcescens (ATCC 274); Staphylococcus albus; Streptococcus sp. B-hemolytic group C and B-hemolytic group C (Henle); Streptococcus pneummoniae (cited as pneumococcus Type I); Streptococcus pyogenes (cited as streptococcus Group A Types 1, 12, 19 and Beta hemolytic streptococcus Group A); Streptococcus viridian; Penicillium chrysogenum (cited as Penicillium notatum). NB These are laboratory studies with a range of outcomes each cited in reported peer reviewed research. Prolitec is conducting research for submission to the US EPA in support of claims as to specific antimicrobial outcomes for specific viruses, bacteria and fungi on surfaces and in the air. Do the triethylene glycol vapors generated by the aria™ system change the humidity in the space being treated? No. The concentration of the vapor is effective at 1 or 2 parts per million and at this level has no measurable impact on humidity.

Triethylene Glycol is not a new chemical. Why is aria™ only now available? Why didn’t this happen years ago? Making triethylene glycol effective as an antimicrobial requires that the liquid be converted into a vapor and then continuously injected into the space to be treated in a metered amount to establish and continuously maintain a uniform concentration in the air. This capability has not been available until the introduction of Prolitec’s advanced air treatment appliances, specifically the Air/Q 550A and the Air/Q 1200A. These appliances are widely used and proven in other air treatment applications in the facilities of major organizations around the world. What are examples of the major facilities using the same Prolitec Air Treatment system that is also used as the aria™ delivery system? A few examples include Aegis Living (www.aegisliving.com) a major assisted-living group; In hospitality: Omni Hotels (www.omnihotels.com) and Sofitel (www.sofitel.com); in gaming: the MGM Grand (www.mgmgrand. com) and Harrahs casinos (www.harrahs.com); in retail: Abercrombie & Fitch (www.abercrombie.com), Hollister (www.hollisterco.com), bébé (www.bebe.com), Bliss spas (www.blissworld.com) and hundreds of other clients.

How does aria™ fit into the infection control program? aria™ is the component that targets airborne bacteria as they are introduced and before they are pulled into the air handling system or settle on surfaces. aria™ is the part of the infection control program that is “always- on,” continuously present in the air and working 24/7 without any staff involvement. What size space does aria™ serve? The aria™ system is modular and scalable to serve any size space from a small room to a large facility. aria™ appliances can attach to the facility’s air handlers to serve larger areas or an entire facility. Other aria™ appli-

22 Air/Q 1200A User Guide © 2010 Prolitec, Inc. Frequently Asked Questions ances are mounted on walls or ceilings to service rooms and smaller spaces or areas not served by air handlers. A portable table-top or floor stand appliance can be moved from space to space as needed. We are a hospital. Where should we consider using aria™? Of course aria™ can be installed to serve the entire facility. A high gain starting point might be areas with the highest risk of infection transmission such as areas with immunodeficient patients, contagious diseases or both. High risk areas for staff should be considered. There is a portable aria™ appliance which can be moved from room to room. Obvious areas include the ER, ICU and recovery as well as isolation units such as TB; dementia, Alzheimer’s and memory care; MS, HIV AIDS and cancer treatment. Areas where infection rate is maintained could be the most valuable in demonstrating aria™ efficacy using before and after comparisons.

How about assisted living, memory care and skilled nursing? Where is aria™ most effective? In these facilities residents are living in close proximity much of the time. The risk and consequences of infection are high. It not only poses a serious health risk for some and is uncomfortable for all residents and staff but it is also very expensive for the community. aria™ can make an important contribution to reducing overall bacteria levels and the risk of infection.

Has the US EPA approved the aria™ system? Yes, the aria™ air sanitizer system is an EPA-registered antimicrobial (Reg. No. 83555-1). What exactly does EPA allow you to say about aria™? Please be sure you read the aria™ label and the MSDS. In brief EPA allows us to call aria™ an “air sanitizer.” What is an “air sanitizer?” The EPA defines it this way: “An [air] sanitizer reduces but does not necessarily eliminate [all] airborne microorganisms …to levels that are considered acceptable according to current health codes or regulations.”8 What does EPA approval actually mean? It means that EPA scientists have reviewed technical data about aria™ including fundamental chemistry and acute toxicity for the use or purpose claimed and approved what we can say about the aria™ on the product label. Is aria™ FDA approved? No. It does not require FDA approval. aria™ is an antimicrobial which is regulated by the US EPA. How about continued exposure to aria™ ? The aria™ system complies with the workplace inhalation standards established by the US Department of Labor, Occupational Safety and Health Administration (OSHA),9 the American Congress and Governmental and Industrial Hygienists (“ACGIH”), and the State of California Environmental Protection Agency.10 The aria™ system produces no known allergens. I know that the ethylene glycol used in my radiator coolant is toxic. Ethylene glycol, a substance found in some automotive radiator fluids, is NOT a component of aria™. Despite similarities in their names, triethylene glycol, the active ingredient in aria™, is a completely different substance from ethylene glycol. Triethylene glycol does not have any of the toxicological characteristics of ethylene glycol.

To be effective as an airborne antimicrobial, how much triethylene glycol is actually in the air? Quantities in the air are typically expressed in parts per million or PPM. The aria™ system employs about 1 to 2 PPM meaning that of every 1 million molecules no more than 1 to 2 is aria™.

© 2010 Prolitec, Inc. Air/Q 1200A User Guide 23 Frequently Asked Questions Will use of aria™ leave a residue on surfaces or damage my HVAC system? No. Properly adjusted to the optimum concentration of 1 PPM there will be no condensation or residue. The Prolitec systems used to deliver aria™ are widely used in commercial air treatment applications for hotels, hospitals, malls, retail stores, fitness centers, spas, skilled nursing and assisted living facilities, and other large facilities. Used as directed, aria™ and Prolitec delivery systems do not leave any residue on surfaces and do not damage air handlers. Will aria™ interfere will the operation of computers and other complex electronic equipment? No. The ultra-low 1 PPM concentrations needed for sanitizing will not interfere with the operation of any electronic equipment. Does the aria™ system require maintenance? Yes. aria™ is provided as a fully-supported monthly service. All maintenance, system adjustment and replen- ishment of cartridges are provided by qualified technicians on a regular basis.

How do I estimate the aria™ cost? The aria™ system is provided as a fully supported monthly service for a fee. There is no equipment to buy but there is an installation charge. The monthly operating charge is based on the total cubic footage of the area served and the ambient air flow and ventilation conditions and can vary from $0.002 to $0.015 per cubic foot (enclosed length x width x ceiling height. What amount of time each month is required of your staff to maintain the equipment and what tasks are performed? Service is required every 30 to 90 days on a fixed schedule worked out with the facility engineering and management team. During service empty cartridges of antimicrobial are removed and full ones installed and levels may be adjusted to optimize efficiency. A technician may be in the facility for a few minutes to several hours depending on the size of the facility. Is system maintenance disruptive to facility routines and does it require any assistance from our staff? No. Service need not be disruptive or require any time from the hospital staff except for the maintenance -per sonnel who may be need to access air handler and oversee the service process. How do you manage malfunctions or breakdowns of your system? The aria™ system is highly reliable and, with regular service, malfunctions are rare. When they do occur, a replacement is installed within 48 hours. Most important, aria™ is modular so a malfunction in any one delivery appliance would affect only one area not the entire system. What is the effectiveness of your system in places such as a lobby that is frequently entered from the outdoors? aria™ is effective in such situations provided the system is sized correctly to take into account the air flow conditions. Is it possible to use the system intermittently (such as only during flu season or an illness outbreak) or must the contract be for continuous use? A permanent aria™ installation is designed to serve as the foundation of an infection control program and to operate 24/7. Small spaces such as a patient or examination room can use the portable table-top appliances available for temporary use in patient rooms or areas less than 2,000 square feet.

24 Air/Q 1200A User Guide © 2010 Prolitec, Inc. Frequently Asked Questions Who determines the continuous levels of aria™ required in a given space and how do we know at any given moments those levels are being sustained properly? Prolitec makes this determination based on its own testing and the body of literature about the efficacy of glycols as an airborne antimicrobial. Prolitec checks this level at the periodic service. Does aria™ have any noticeable odor? The aria™ system is odorless. Does aria™ eliminate odor? aria™ does not eliminate all odor but it does remove odors caused by certain bacteria.

FAQ Endnotes 1. EPA Registration Number 83555-1 2. U.S Environmental Protection Agency, DIS/TSS-11 / Sep. 3, 1980; EFFICACY DATA AND LABELING REQUIREMENTS: Air Sanitizers http://www.epa.gov/oppad001/dis_tss_docs/dis-11.htm 3. US Environmental Protection Agency Reregistration Eligibility Decision for Triethylene Glycol, p 1 List C, CASE 3146, 9/26/2005. “Based on a review of the available toxicology data, the Agency has concluded that triethylene glycol is of very low toxicity by the oral, dermal, and inhalation routes of exposure…. The Agency has no risk concerns for triethylene glycol with respect to human exposure” 4. Occupational Health and Safety Administration, U.S. Department of Labor, Part 1910, Occupational Safety and Health Standards, Subpart Z Toxic and Hazardous Substances 1910.1000 Air contaminants. www.osha.gov The active ingredient is aria™ ® is not included on this list of maximum workplace air concentrations of substances identified as potentially toxic our hazardous, 5. State of California, Environmental Protection Agency, Office of Environmental Health Hazard Assessment, www.oehha.org. Safe Drinking Water And Toxic Enforcement Act Of 1986 puruant to Proposition 65; Chemicals Known To The State To Cause Cancer Or Reproductive Toxicity 6. U.S Environmental Protection Agency, Pesticide Registration Manual: Chapter 4 - Additional Considerations for Antimicrobial Products. 7. Op Cit U.S Environmental Protection Agency, DIS/TSS-11 / Sep. 3, 1980; 8. U.S Environmental Protection Agency, Pesticide Registration Manual: Chapter 4 - Additional Considerations for Antimicrobial Products 9. Occupational Health and Safety Administration, U.S. Department of Labor, Part 1910, Occupational Safety and Health Standards, Subpart Z Toxic and Hazardous Substances 1910.1000 Air contaminants. www.osha.gov The active ingredient is aria™ ® is not included on this list of maximum workplace air concentrations of substances identified as potentially toxic our hazardous, 10. State of California, Environmental Protection Agency, Office of Environmental Health Hazard Assessment, www.oehha.org. Safe Drinking Water And Toxic Enforcement Act Of 1986 puruant to Proposition 65; Chemicals Known To The State To Cause Cancer Or Reproductive Toxicity

• Do not install or store Air/Q 1200A outdoors or in places where the ambient temperature may fall below 0 degrees Celsius (32 degrees Fahrenheit) or rise above 54 degrees Celsius (130 degrees Fahren- heit). (If operating conditions must be outside these ranges, contact Prolitec Safety and Support Hotline at 888.615.9282). • Do not drop Air/Q 1200A on the floor. Do not drop it in or position it near an open basin of water. • Do not paint or otherwise try to alter the color of the outer cover. • Always keep the lids on Cartridges when stored outside of the Air/Q 1200. • Do not operate Air/Q 1200A in very dusty areas that may cause the air intake to clog. • Do not move or transport an appliance with a cartridge installed. • Please call Prolitec Customer Service at 866.387.4333 for return shipping instructions or questions.

XI. Specifications

Air/Q 1200A Technical Characteristics Reference Air/Q 1200A : Model AQ1200A Type 1 head nebulizer integrated with cartridge Diameter of particles 300 nm to 1µ micron Power Input Input 100 – 240 VAC at 0.6 A Frequency 50/60 Hz Protection Switching power supply Internal Power 12 VDC at 1.5 A Back-up battery Lithium 3V, #CR2032 Performance Up to 150,000 cu. feet (4,200 cu meters) subject to air flow conditions Control Programmable start & stop times Programmable output 1 to 50 Dimensions Height X Width X Depth 15 1/2” X 13 3/8” X 6 3/4” (39.4 cm X 34.0 cm X 17.2 cm) Weight with full container 13.7 lb (6.2 kg) Approvals UL/CSA listed power supply

Cartridge Reservoir - 1250ml Disposable/Recyclable

Patented Prolitec Inc. Multiple patents pending