Efficacy and Long-Term Outcome of Treatment for Pure
Biol Blood Marrow Transplant 19 (2013) 1026e1032 Efficacy and Long-Term Outcome of Treatment for Pure Red Cell Aplasia after Allogeneic Stem Cell Transplantation from ASBMT American Society for Blood Major ABO-Incompatible Donors and Marrow Transplantation Makoto Hirokawa 1,*, Takahiro Fukuda 2, Kazuteru Ohashi 3, Michihiro Hidaka 4, Tatsuo Ichinohe 5, Koji Iwato 6, Heiwa Kanamori 7, Makoto Murata 8, Toru Sakura 9, Masahiro Imamura 10, Soichi Adachi 10, Ritsuro Suzuki 10, Yasuo Morishima 10, Hisashi Sakamaki 10, for The PRCA Collaborative Study Group 1 Akita University, Akita, Japan 2 National Cancer Center Hospital, Tokyo, Japan 3 Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan 4 National Hospital Organization, Kumamoto Medical Center, Kumamoto, Japan 5 Kyoto University, Kyoto, Japan 6 Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Japan 7 Kanagawa Cancer Center, Yokohama, Japan 8 Nagoya University Graduate School of Medicine, Nagoya, Japan 9 Saiseikai Maebashi Hospital, Maebashi, Japan 10 Japan Society of Hematopoietic Cell Transplantation, Nagoya, Japan Article history: abstract Received 12 November 2012 No standard of care for pure red cell aplasia (PRCA) after major ABO-incompatible hematopoietic stem cell Accepted 5 April 2013 transplantation (HSCT) has been established. We conducted a retrospective cohort study to learn the efficacy and outcome of treatment for PRCA. One hundred forty-five recipients who showed delayed recovery of Key Words: erythropoiesis and survived >100 days after transplantation without early disease progression were selected Major ABO-mismatched HSCT from 2846 records of major ABO-incompatible transplantation in the registry database in Japan, and detailed PRCA data of 46 recipients were collected.
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