2019 CONTENTS OVERVIEW 4 Message from the president

7 About us

8 Organization

9 History of Taiwan Blood Services Foundation (1974~2019)

OUR PERFORMANCE

14 Recruitment and retention of blood donors

19 Blood operation process

20 Blood donation operation process

23 Blood testing

25 Blood donor services

26 Component processing

29 Distribution

31 Reference laboratory

31 Research

32 Blood transfusion safety

32 International exchange and training plan

33 Information business and network security

38 Reward records

40 Quality assurance STATISTICS

42 Annual blood collection, 1974-2019 54 Pre-donation donor deferral in 2019

43 Annual blood collection by blood 55 Infectious disease screening for blood centers, 1974-2019 issue in 2019

44 Annual blood supply, 2010-2019 56 Irregular erythrocyte antibody detected in 2019 45 Blood and blood components issued in 2019 56 Detection of donor Mia antigen in 2019

46 Whole blood collection per 1000 head 57 Statistics of ABO and RhD in 2019 of population, 2010-2019 57 Statistics of ABO subgroups in 2019 47 Blood donation by blood centers, 58 Inventory of rare RBCs 2010-2019 59 Human resources in 2019 48 Types of blood donation in 2019 60 Incomes and expenditures in 2019 48 Types of whole blood donation, 2010-2019

49 First-time donors in 2019

49 Trends in the rate of rst-time donors, 2010-2019

50 ≤24 age rst-time donors, 2010-2019

51 Distribution of donor by gender and age in 2019

51 Gender ratio by age

52 Donation frequency by gender and age in 2019 APPENDIX 52 Blood collection by sites in 2019

53 Occupational distribution of donors 62 Blood centers in Taiwan in 2019 63 Blood centers and stations We are planning and constructing the the constructing and planning are We Blood Patient of the concept promote To nation’s first blood component manufacturing manufacturing blood first component nation’s to is plan initial The Taiwan. southern in center processing the blood component incorporate Kaohsiung and in Tainan laboratory testing and the followed already have We Blood Centers. the fully automated and GMP standards PIC/S and safety its upgrading greatly thus operations, the will be developed into center This quality. in Taiwan. blood center world-class 2019 a in April held we (PBM), Management meeting, to promotion blood management patient northern in hospitals from representatives which their experience in share to invited were Taiwan the valuable to listened to clinical practice and addition, In physicians. various from suggestions Blood its and the TBSF from the physicians medical lectures hold to continued have Centers to hospitals, of a number at blood transfusion on effective and "appropriate of the concept advocate — therapy "bloodblood component transfusion", Message from the president from Message Last year, with the joint efforts of every every of efforts the joint with Last year, Taiwan’s medical standards are well known to to known well are medical standards Taiwan’s colleague of us, we also have remarkable remarkable also have we us, of colleague the continuous including achievements, blood leukocytes the use of reduced of promotion in 102 hospitals Currently, in hospitals. products fully used RBCs, leukocytes have reduced Taiwan the improve To rate. a 54.1% utilization reaching also tested service have we blood transfusion, of Jka, C, c, E, e, as such blood red cell antigens, on the for convenient more it making Mia, and Jkb, antigen-negative obtain blood to banks hospital to in a hope cross-matching for blood products services Medical time. waiting thepatient’s reduce optimized. is all. We at the Taiwan Blood Services Foundation Blood Services Foundation the Taiwan at all. We collect to and hard been working have (TBSF) the clinical use throughout blood for supply safe and stable provide to continue We country. actively and citizens our for blood transfusion blood technology of to in the development invest quality. blood and safety further improve

OVERVIEW 4 OVERVIEW 5 In terms of blood donor services, we services, blood donor of terms we In of which were certified with the SNQ (Symbol certified (Symbol which were the with of SNQ Silver with conferred Quality) and National of in the National respectively Awards Bronze and once we Clinical QualityAward, Biotechnology Bronze and SNQ the certification of won again Clinical Biotechnology in the National Award of thetheme presenting by 2019 in Award Quality Taiwan, in southern patients for angel " Guardian --Kaohsiung islands offshore and areas remote has the TBSF that evident is It ". Blood Center all for level been highly the affirmed national at performance. aspects its of Following the theme of “ The Pioneer of of Pioneer “ The of the theme Following Safe and Sufficient Blood Supply ” in 2017 and ” in 2017 and Blood Supply Sufficient and Safe highly and “Thethe of theme comprehensive blood to donor of testing efficient laboratory in 2018, both in Taiwan” safety transfusion ensure and various surgical methods and take the take the methods and surgical various and inappropriate the need decrease for to initiative unnecessary Meanwhile, and blood transfusions. also Blood revised of the "Essentials have we in physicians assist to in order Components" concepts, blood correct transfusion establishing use all the blood accurately they more so can that the recipients. to components the advantages and clinical and the advantages leukocyte- of application blood products" reduced blood patient other and is It concepts. management all the hospitals that hoped will review and to be able their blood use control diseases various of patterns Since its establishment on January 1, 1990, 1, 1990, January on establishment its Since allowing more young people to participate blood participate to people young more allowing donation. in role indispensable an played has the TBSF 30 for health system medical and Taiwan's promote to will we continue the future, In years. blood industry Taiwan's of the development will public we the further general and enable and the blood donation understand better to that hoped is It country. in our situations supply blood thenational willus support everyone of the stable sufficiency maintain policy help and blood services. Faced with the social trends of declining the declining with social of Faced trends birth rate and population aging, the TBSF will will the TBSF aging, population and birth rate people, young try our further best to its educate combining in between by the gap narrow and attention their gain to elements popular various is It blood donation. of their fear eliminate and of value the mission on pass can we that hoped health, of the importance and blood donation have since October 18, 2019 promoted the the October since 18, 2019 promoted have a barcode everypolicy wear to for blood donor the Blood with connected is which wristband in can, a donor so that System, Management be right identified process, theblood donation code,making bar her or his scanning by away research of terms In smoother. even the process in engaged only not have we publication, paper papers many published but researches, multiple of two journals, international and in domestic places third and the second even won which have the Journal from Award Best Paper in the annual (THA). Association Hospital Taiwan of

OVERVIEW 6 OVERVIEW 7 To establish blood donation systems, and to to and systems, blood donation establish To safe on development and research conduct blood use. blood science on and research conduct To technology. blood supply and collect laboratory-test, , To hospital. private and public of patients for the health maintenance on research conduct To blood donors. of the use and concerning matters conduct To for blood suitable of management safety transfusion. at quantity blood in large supply and plan To wars. or disasters major times of storage , to fractionation toll commission To products. derived plasma domestic supply and and blood donation concerning Other matters supply.

2. 3. 4. 5. 6. 7. 8. 9. About us About Adhering to sustainable development under under development sustainable to Adhering Upholding the concept of "happy blood blood "happy of the concept Upholding To plan and implement blood donation blood donation implement and plan To services.

the principles of integrity, harmony, efficiency, and and efficiency, harmony, integrity, of theprinciples the become leader to vows the TBSF innovation, clinical uses in Taiwan. safe for in blood supply donation and safe blood use," the TBSF practices blood the use," TBSF safe and donation blood donation non-remunerated a voluntary and strict on control blood quality insists system, services blood for complete the most provides a ensure so to as blood recipients and donors clinical uses. for bloodsufficient supply 1. Our Missions Our Vision Our Aim Oce **Auditing Kaohsiung Kaohsiung Division of Division Blood Center Medical Aairs Medical Changhua Blood Station of Quality Division of Division Department Administration Miaoli Taitung Committee Blood Station Blood Station Medical Advisory Medical Accounting Tainan Tainan Blood Center of Finance of Department Makung Taoyuan Management Blood Station Blood Station Division of Administration of Division Aairs General Technology Department of Information Blood Hualien Supply Pingtung Taichung Taichung President Blood Center Blood Station Blood Station Vice President Vice Board of Directors Board of Chief Executive Ocer Chief Executive Deputy Executive Ocers Executive Deputy of Public Public of Relations Department Processing Component Yilan Chiayi Division of Technology of Division Organization Blood Station Blood Station *Testing Laboratory of Research of Department Hsinchu Hsinchu Blood Center Data Yunlin Banqiao Processing Blood Station Blood Station Department of Operation of Blood Collection Puli Division of Operation of Division Keelung Taipei Taipei Blood Station Blood Station Donor Aairs Blood Center of Medical Medical of Department Recruitment Note: * Note: Blood Center. Kaohsiung and in Taipei laboratories testing 2 centralized are ere set Oce was up. ** 1, 2020, the Auditing Jan of As

OVERVIEW 8 OVERVIEW 9 (1974~2019) History of of History 1981 1983 1976 1978 1975 1974 Taipei Blood Center introduced leukocyte and platelet apheresis. leukocyte platelet and Blood introduced Center Taipei Taipei Blood Center started the production and supply of blood components, including packed packed including blood components, of supply and the production started Blood Center Taipei plasma. frozen and plasma frozen fresh platelets, RBC, RBC, washed WBC concentrates, established. Blood was Center Tainan The Kaohsiung Blood Center was established. Blood was Center Kaohsiung The Taichung Blood Center was established. Blood was Center Taichung Taipei Blood Center was established. Blood was Center Taipei Chinese Blood Donation Association was established. was Association Chinese Blood Donation

• • • • • • • July July April August January October Taiwan Blood Services Foundation Taiwan December 1992 1993 1991 1990 1987 1988 1989 1985 To prevent blood donations from high-risk AIDS groups and other unsuitable donors, the the donors, unsuitable other and high-risk AIDS groups from blood donations prevent To call could notify to the donors whereby call”, phone confidential started “a Blood Centers unsuitable. is if the bloodBlood donated Centers Introduction of HLA-matched apheresis platelets. apheresis HLA-matched of Introduction Chinese Blood Services Foundation which is the predecessor of Taiwan Blood Services Taiwan of Chinese Blood the which predecessor is Services Foundation established. was Foundation Implementation of anti-HIV-I test. anti-HIV-I of Implementation Human leukocyte antigen (HLA) laboratory was established. was (HLA) laboratory leukocyte antigen Human Hualien Blood Center was established. Blood was Center Hualien rate theblood donation and units, million exceeded one blood donations annual The 5.18%. reached Hospital-based and Red Cross paid donor blood banks closed. donor paid Red Cross and Hospital-based Hsinchu Blood Center was established. Blood was Center Hsinchu test. anti-HCV of Implementation cell phenotypes. red of database electronic of Establishment

• • • • • • • • • • • July May June April January January February December December

OVERVIEW 10 OVERVIEW 11 2007 1999 2001 1997 1998 1996 1995 It is the first time, the President met the 28 outstanding blood donors in the presidential in the presidential blood donors the 28 outstanding met the President the time, first is It event. recognition blood donor annual palace for Implementation of a computer system to replace manual work of blood donation and and blood of donation work manual replace to system a computer of Implementation processing. Consolidation of 6 blood centers’ testing labs into 2 centralized labs located in Taipei and and Taipei in located labs centralized 2 into labs testing blood6 centers’ of Consolidation blood centers. Kaohsiung supply. started to products “TBSF”The derivative plasma Implementation of RBC irregular antibody screening test. screening RBC antibody of irregular Implementation 2013. ended in January was plan The blood established. bank was cord umbilical public first The The Blood Centers got approval of the MCA (Medicines Control Agency) and sent source source sent and Agency) Control (Medicines the MCA of approval got BloodThe Centers Service). Blood Transfusion National (Scottish SNBTS of plant fractionation plasma to plasma Implementation of bacteria testing for all apheresis platelets. all apheresis bacteria for of testing Implementation The Minister of Department of Health, Chang Po-ya and the President of TBSF Lin Kou-Sin Lin Kou-Sin TBSF of the President and Po-ya Chang Health, of Department of Minister The products. derivative plasma of start the productions to announced Implementation of anti-HTLV test. anti-HTLV of Implementation

• • • • • • • • • • April April March August January January January February December September 2019 2017 2018 2016 2013 2015 2009 The archive sample bank built in Hsinchu Blood Center was launched. Blood was Center in Hsinchu bank built sample archive The The new Blood Management System based on Internet Data Center was launched. was Center Data based Internet on System newThe Blood Management been introduced. have RBC of Antigen Mia screening universal The in Taipei. Forum the Policy 5th Blood APEC Safety at hosted TBSF The Haemovigilance reporting system was launched. was system reporting Haemovigilance blood centers. Kaohsiung and Taipei into merged and reorganized was blood center Hualien Implementation of the mobile social communication app LINE official account named named LINE official account app social the mobile of communication Implementation broadcast push instant and personalized notification query, “ i-Blood intelligent ” with functions. Implementation of Nucleic Acid Amplification Testing (NAT). Testing Amplification Acid Nucleic of Implementation The TRALI (transfusion-related acute lung injury) prevention policy was initiated with the with policy initiated was injury) prevention lung acute TRALI (transfusion-related The 2) HLA & HNA transfusions. for prioritized was 1) male plasma initiatives: two following donors. apheresis female for screening antibody those every who have HbA1c tests for and 3 years LDL-C, cholesterol, of Implementation old. 40 years above are and blood years 2 in the past donated The singer, Miss Fang Wu, our blood donation spokesperson, composed the song to to the song composed spokesperson, blood donation our Wu, Fang Miss singer, The blood. give to the public encourage RBCs. leukocyte-reduced for Jkb Jka, and C, c, E, e, RBC of antigens labeling and Testing

• • • • • • • • • • • • July June April August January October February December November November September

OVERVIEW 12 OUR PERFORMANCE Taiwan’s fastest man Chun-han Yang. Chun-han man fastest Taiwan’s talented singer-songwriter Lala Hsu (Jia-ying), (Jia-ying), Lala Hsu singer-songwriter talented (Pei-tzu), Tseng Pets idol the new-generation and Wu, Fang the singer-songwriter new female have We Yang. Chun-han man fastest Taiwan’s also used videos, but filmed only promotional not voluntary of the concept spread to the Internet recently has Wu Fang Moreover, blood donation. the for song advertising a testimonial created more urge use to influence her to hoping TBSF, blood donors. of the ranks join to people OUR PERFORMANCE OUR Involving celebrities to assist in the the in assist to celebrities Involving Since its inception, the Taiwan Blood Services the Taiwan inception, its Since Recruitment and retention of blood of retention and Recruitment donors promotion of blood donation has always been a always has blood of donation promotion artists Many publicity. method of very important blood donation of the importance who know in shooting charge, free of their help, offered have these All are of posters. or advertisements us. to resources helpful and precious extremely the hot-blooded youth launched recently have We "Young of the slogan under campaign recruitment in the blood donation promote to Blood " hoping have we the campaign, For population. young the as such “spokespersons”, of a number invited Foundation (TBSF) has been promoting the the been has promoting (TBSF) Foundation blood non-remunerated voluntary of concept angles multiple from public the general to donation 1991, In step. by expecting step actualizeand it to million blood exceeded one donated of the amount the international exceeding thetime, first for units rate. blood donation national 5% for of threshold among been has thenranked since Taiwan Thus, blood donation. of in terms countries advanced

OUR PERFORMANCE 14 OUR PERFORMANCE 15 The new female singer-songwriter Fang Wu. Fang singer-songwriter newThe female The video clips for blood donation. for videoThe clips Before the Lunar New Year every year, when the weather when the weather every year, Year New the Lunar Before We need the public to help balance the blood supply the balance bloodsupply help to needthe public We Former presidents of Taiwan including Lee Deng-hui, Lee Deng-hui, including Taiwan of presidents Former is cold and every family is busy preparing for the coming the coming for preparing every busy and is cold is family the long during fall usually short blood supply festival, blood transmission for waiting patients period, but holiday all. Therefore, at a luxury taking such holiday of have do not the as Year New the Lunar before month the one designate we and demand. In addition to continuously advocating and and advocating continuously to addition In demand. and non- voluntary of the concept so that the public educating also we be can popularized, blood donation remunerated social groups, business the civil society, try involve to this achieve us help to groups religious and organizations in assist to effort no spare they always Luckily, mission. the country. across activities blood donation launching also we campaigns, blood donation regular to addition In can blood donors so that bloodmobiles, build to funds raise All environment. blood donation comfortable a more have the based community, the trust of on are these dedications Without in the people society. enthusiastic and enterprises, the with theidentification trustand mutual sense of a strong so many accumulate cannot we blood of donation, concept blood donation voluntary of the cause for social resources model in the international exemplary an become and the society "taking from of Based the concept on community. to help enterprises the society", to back giving many and us helps only not This activities. blood donation promote enhance themselves also helps but bloodrecruit sources, a win-win achieving effect. image, welfare their public Chen Shui-bian, and Ma Ying-jiu all publicly support blood support all publicly Ying-jiu Ma and Chen Shui-bian, blood, while most donate to people encourage and donation blood regular are mayors city and magistrates the county of they shortage, blood a is supply there Whenever donors. persuading in role leading a play to effort no spare always blood. donate to people In 1995, we held for the first time the the time thefirst for held we 1995, In high-profile "Love One" event, in which 28 in which 28 event, One" "Love high-profile outstanding with blood donors representative from recognition received merit donation Office. the Presidential at Lee Teng-hui President been have then, qualifiedSince blood donors the limited to due However, every year. consulted of Office, the number the Presidential in space Thus, 38 each year. to limited is representatives World Blood Donor Day press conference on on conference press Day Blood Donor World Be and "Love the of with 15, 2019 theme June Wu, Fang Miss event, that In You!" Thank Loved, ambassador, blood donation new-generation our Be and "Love song newly composed her sang of flow the and transition the symbolize to Loved" blood receivers; and between blooddonors love blood with donate to fans her also asked Wu Miss Yin, Shui the scene. at the bloodmobile on her Iron of the title with dubbed a blood receiver blood a as donate to Wu Miss accompanied Girl, all to blood donors. gratitude express to symbol In order to connect with the world, we we the world, with connect to order In 2019. TBSF CEO, Wei Sheng-Tang led all the young donors to swear the theme of "Love and Be Loved, Thank You!" Be Thank and Loved, "Love the of theme swear to donors led all the young Sheng-Tang Wei CEO, 2019. TBSF always follow the World Health Organization Organization Health the World follow always Blood Donor the "World organize to (WHO) the public's every awaken to event year Day" series a through blood donation for enthusiasm in 2019 was the WHO of theme activities. The of encourage to all", meant which is blood for "Safe blood safe provide to the world around countries voluntary of medical use the premise under for the held We blood donation. non-remunerated Blood Donation Month so as to remind ourselves ourselves so remind to as Month Blood Donation reserve to sufficient harder even work must we that the at Therefore, the holiday. blood for stocks safe will we hold Month, Bloodbeginning Donation of make only will which in we not conference a press in status the blooda summary on donation report blood. also give to call people but on year, the past activities will a series regional we host of Moreover, they that hoping people, of the attention attract to the alleviate help to in winter warmth willprovide medicalshortfall blood. of

OUR PERFORMANCE 16 OUR PERFORMANCE 17 Duncan campaign poster. campaign Duncan the slogan of "I am young! I donate blood!" It blood!" It I donate young! "I am of the slogan can 20 to 17 aged people young that hoped is so blood 4 years, 10 times within donate to come seeing blood donors, theyregular become that keeping and their life part as of blood donation blood to safe give so lifestyles to as healthy on 13, 2019, the cumulative June of As others. help 274,658, among reached participants of number 161 including blood 293 whole whom donors, theof goal achieved have girls, 132 and boys for 16 units and boys for 24 units donating 15, June on Held years. the four during girls and the "Love for conference a press 2019 was in which several event You!" BeThank Loved, blood of the number highest with representatives experience their share to invited were donations blood. donate to people more encourage to and youths passionate call more to on addition, In also have blood,we donate to out come to graphic online an Duncan, with cooperated nation- hold to followers, 3 million with creator Can Juan Ni “Dun as dubbed events wide campus donate willing to are you “when – literally Xue” In recent years, due to declining birthrate birthrate declining to due years, recent In and aging population, the number of young blood young of the number population, aging and becomes it and decreasing, gradually is donors donated of the volume that trend inevitable an in the resulting year, blood by will year decline solve To in the future. blood sources of depletion we that matter urgent an is dilemma, it such people young more and more encourage should in a habit develop to blood give regularly, to healthy maintain to and blood donation, regular 2015 launched since have we Therefore, lifestyles. under campaign Blood ” recruitment the “Young we ask each Blood Center to firstly divide the the divide firstly each Blood to ask Center we blood "whole donation" categories: two into quota select then sort and and donation" "apheresis and in donations of the number by the representatives this a once-in-a-lifetime is As order. descending every recognition, a national-level and honor in splendid this event attends blood donor invited exerted only not has this event Obvious, attire. blood of the promotion on influence positive a social also blood and gives ethics, but donation and the glory state meet the head of to donors Former her. or him with photos take group to Chen Shui- Lee Teng-hui, including presidents the acting president and Ying-jeou, Ma bian, blood outstanding all received have Ing-wen Tsai blood donation, supported publicly donors, blood. donate to the public encouraged and the each Blood holds Center addition, In in its Ceremony" Awards Blood"Annual Donor the highest express to jurisdiction every year, grand but in a simple gratitude respect and all military, to schools, those individuals, way enterprise business associations, institutions, blood donations. their outstanding for groups get help in the shortest possible possible in the shortest help get the usera receives After time. to wants she or if he and message meets she or whether he check or blood donation, for the criteria blood donation the nearest where an make can she or he is, point inquirythe official LINE through this LINE official As account. all addresses the needs of account our up doubles it blood donors, powers. diffusion and mobilization The blood donation career is built upon upon built is career bloodThe donation occurs and a disaster or emergency an When artists and Youtubers, can urge more young young more urge can Youtubers, and artists blood to donation. attention pay to people make must We step. by step engagement public to all life walks from of good resources use of the activities, maximize blood donation promote and resources, limited of impact and effectiveness medical donated effective use the of most make social in lifestyle, structure, changes blood.With the with development coupled media ecology, and digital of the popularization and the Internet of and upgrade to also continue must we vehicles, the times. with publicity of the power strengthen in 2016 the first pioneered the TBSF Therefore, “ i-Blood named ” through LINE official account personalized notification query, which intelligent provided. are broadcast push instant and specific of blood type needed, is amount a large this LINE official send through can account we those with to qualified blooda request donors specifica such blood type specifica in region, blood needcan of emergent in an people so that "Good Hearts and Good Hugs", a Hotai Motor-sponsored Motor-sponsored a Hotai Good"Good and Hugs", Hearts blood donation. promote to micro lm welfare public The "Er Mei" blood donation mobile stationed in Ximending is the first the first is in Ximending stationed mobile blood donation "Er Mei" The in Taiwan. mobile blood donation anime blood” – at colleges, universities, high schools high schools universities, colleges, at – blood” In the country. around schools vocational and each opened, 2019, when school September, “Duncan” dedicated own its out Blood sent Center among blood donation advocate to bloodmobile limited set a of whom to the donors, first-time exclusive an as given was tapes paper edition small This gift succeeded in arousing souvenir. Ni “Dun of discuss the topic to students young friends his also Duncan invited Xue”. Juan Can the subject promote all to life walksfrom of as their influence, that hoping the stage, on matter

OUR PERFORMANCE 18 OUR PERFORMANCE 19 Blood Blood supply process Hospitals Component sent to the Laboratory for viral, biochemical, & & biochemical, viral, for the Laboratory to sent are results blood-type examination The testing. storage. for the computer to delivered automatically Each the Blood blood to sent Component bag is Section be to furtherProcessing each as processed RBCs, packed as such final product, plasma of kind each qualified blood Finally, so on. and platelets, Section based willbag the Distribution to be sent the hospital. the needs of on Fully Fully Fill out the Fill out Registration Datebase Blood collection Donor interviewDonor computerized Donor recruitment Donor Healthy Questionnaire Healthy Testing The production of each bag of blood results blood results of bag each of production The Blood process operation from regional blood donation activities held activities held blood donation regional from the Donor by planning and the evaluation after The Section theBlood Center. Recruitment of filed is blood each donor of information personal the completes the blood after donor stored and the physical form, registration blood donation theblood collecting and interview, examination collected blood of each tube Then, is process. The “Private Interview Space” is arranged to enable enable to arranged is Space” Interview “Private The the questionnaire answer honestly to blood donors surroundings. in private questions related and Each person needs to fill in the blood donation Each fill needs person to in the blood donation basic to addition in which form, registration recent concerning also questions asks information, a high is whetherthere and health status individual need to that issues other and sexual of risk behavior each person needs to Lastly, honestly. be answered sign the form. A “Private Interview Space” is arranged in each blood center, blood donation room, and blood blood and room, blood donation blood each in center, arranged is Space” Interview “Private A Blood donation operation process operation Blood donation donation van so that each blood donor can honestly complete the survey and relevant questions in private in private questions the survey relevant and complete honestly can blood each so donor that van donation process: the blood to donation introduction an is following The surroundings. Inside the blood donation van, each seat is equipped equipped is seat each van, the blood donation Inside video a health lesson plays that a monitor with of blood donors remind to blood donation about blood safety. of the importance A photo ID, such as an Identification Card of of Card Identification an as such ID, A photo a blood of needed verify is to the identity Taiwan 2019, In process. the blood donation during donor their blood donated people million one than more 6 billion approximately reached so the blood supply milliliters.

OUR PERFORMANCE 20 OUR PERFORMANCE 21 Each blood unit will have four tubes reserved for reserved tubes for four Each will blood unit have viral, biochemical, for them are of Three test. each archieve for is one the other blood-type and testing sample. The “Conscience Call Back” sheet can remind blood remind can sheet Call Back” “Conscience The call via back to the phone the blood center donors follow- appropriate ensure the to sheet on number the blood if be of can carried out treatment up high-risk of health professionals told not they have affect they think that may issues any or behaviors the blood. of the safety In addition to measuring weight, body temperature, body temperature, weight, measuring to addition In a staff will provide hemoglobin, and blood pressure that ensure blood and safety about health education step the qualified. first is is This the blood donor blood check. safety for During the blood collection process, each blood each blood During the blood collection process, weight for oscillator in the automatic put bag is collected blood of is the quantity and measurement, blood donors. of the safety protect to monitored 60 kg 17-65 2 units MCS: 300,000/uL MCS: Trima: 250,000/uL Trima: Amicus: 250,000/uL 2 weeks 24 donations Platelet apheresis Platelet 60 kg 17-65 1 unit 180,000/uL male: 13g% 35.5~37.5°C female: 12g% female: The collected blood and tubes will be delivered willcollected tubes The blood be and delivered in dedicated professionals by the bloodto center trolleys. and incubators In the bright and open blood donation rest area, area, rest blood open donation and the bright In served. milk cookies are like and Magazines snacks blood so that in the area TVs alsoand provided are the process. after relax can donors 60 kg 17-65 500 ml 3 months Whole blood male: 1500 cc female: 1000 cc female: 17-65 250 ml 2 months male: 50 kg female: 45 kg female: Age Volume Interval Body weight Hemoglobin Platelet count Platelet Oral Temperature Max donations per year donations Max The collected blood will be temporarily stored in in collected The blood stored will be temporarily maintain to container temperature-controlled a quality. The following table lists relevant criteria and conditions for blood donation: for conditions and criteria relevant lists table following The

OUR PERFORMANCE 22 OUR PERFORMANCE 23 The specimen will undergo a centrifugal operation a centrifugal operation specimen willThe undergo testing fully automated of the convenience for process operations. fully automated a fast in order, ranked are tubes After obtain safely and accurately performed scan to is barcode information. Daily inspection operations can accommodate up to 6,000 to up accommodate can operations inspection Daily equipment. testing fully automated using specimens to network exclusive via an delivered are results Test speed, of themeet goals to center blood each donation safety. and accuracy, To ensure that the quality of examination is consistent and labor costs are kept low, laboratory testing testing laboratory low, kept are costs labor and consistent is examination of the quality that ensure To Blood testing is mainly performed in two sites. Testing Sections in Taipei Blood Center and Kaohsiung Blood Center are Blood are Center Kaohsiung Blood and Center Sections in Taipei Testing sites. performed in two mainly is ABO include: items examination standard Currently, operations. blood examination nationwide of in charge syphilis, anti-HIV, anti-HTLV, anti-HCV, HBsAg, blood type, Rh ALT, screen, blood antibody type, irregular follows: as is procedure operating examination The HIV-1). and HCV, (HBV, acid testing viral nucleic and

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OUR PERFORMANCE 24 OUR PERFORMANCE 25 In addition to the routine regular blood blood regular the routine to addition In Blood services donor donation testing, since November 1st 2015, 2015, 1st November since testing, donation also has tests, performed three Foundation our & HbA1c, LDL-C, Cholesterol, Total namely, blood donors consenting every for years three donated have and old 40 years than older who are years. two the past within once than blood more in the test shown is a blood donor BMI of The positive a shown who have Bloodreport. donors are tests HCV) and (HBV hepatitis to response messages. (referral) counseling with provided older who are blood donors for Furthermore, blood donated have and old 40 years than if years, two the past within once than more 100 than blood whole more donated they have 500 times, than blood more apheresis times or ultrasonic free abdominal one they receive can appointed Foundation’s our of in one examination hospitals. Using the theme of “Comprehensive and and “Comprehensive of the theme Using Since December 5, 2018, the TBSF has December has Since 5, 2018, the TBSF In 2016, the TBSF sent staff to the Kanto- staff to sent the 2016, TBSF In highly efficient laboratory testing of donor blood donor of testing highly efficient laboratory Taiwan of in Taiwan Safety Transfusion ensure to in the participate to Blood Services Foundation” National of (Symbol 2018 SNQ for accreditation - Medical “Peripheral of Quality) in the category passed the TBSF Service Group,” Welfare Public the win the certification. to Later, the evaluation in the Award” “Bronze even awarded was TBSF Quality Care Medical and Biotechnology National Award. expanded its tests on the Mia antigens, and up up and antigens, the Mia on tests its expanded antigen-negative 130,000 Mia than more now to All been the Mia tested. have blood donors of bag each on indicated are results test antigen needs if a patient so that bloodred cell products, blood products, thetransfuse antigen-negative to select blood directly the right can the hospital the blood on the labeling to according products the them patient. inject to immediately bags and each on antigen blood Mia group of labeling The the in new the first record only bloodnot is bag blood bank to the hospital also helps but world, safety. blood transfusion improve effectively Koshihisa Blood Center, Japanese Red Cross Red Cross Japanese Blood Center, Koshihisa monoclonal of the production study to Society, blood then types rare and for reagents antibody stably can that cell line the hybridoma produce Anti-Mia. of the antibody secrete and subculture Based on different centrifugal criteria, different centrifugal different criteria, Based different on befinal can produced. blood products in the upper plasma into Blood be can separated based on layer blood red in the cells lower and layer density. blood composition different of theprinciple can extractor blood components automatic The be to bags sealed. adjunct into out squeeze plasma After non-remunerated blood donated is returned to the blood donation center, it will go through the will through it go center, the blood to donation returned is blood donated non-remunerated After Component processing Component counting process, computer input, blood component processing, checking and bacteria testing (Apheresis bacteria (Apheresis and testing checking processing, blood component input, computer process, counting each final to will These a variety final of blood be products products. besupplied to into made platelet) strict processes. blood testing undergoing after blood transfusions patient for hospital The number of blood units is counted and recorded recorded and counted is blood units of number The in the computer. Generally, blood will be sent to the Component blood will the Component to be sent Generally, blood collection. of Section 8 hours Process within

OUR PERFORMANCE 26 OUR PERFORMANCE 27 Separated plasma and each final product needs needs final each product and plasma Separated for stacking avoid to placed neatly beto carefully freezing. uniform Qualified blood products are put in blue baskets while baskets in blue put Qualified are blood products with while baskets; ones in red put are unqualified ones and baskets, in green put are blood products quarantined baskets. in yellow been are examined not have that ones Every blood bag has a unique barcode and blood- and barcode Every blood a unique bag has testing. further and type checking, tracing, for label Using a leukocyte reduction filter or inline filtration inline filtration or filter a leukocyte reduction Using blood blood immune triggering cells bags, white an the blood make safer to be can removed response recipients. transfusion for Packed RBC is sealed into four sections for blood sections for RBC four sealed is Packed into in the future. matching cross and testing group blood a unique section has Each blood bag tubing testing. further and tracing, checking, for number 925 475 675 300 300 300 200 575 150 7,300 1,375 4,300 Cost (Dollar/ unit) 6°C 24°C 6°C 6°C 6°C 24°C 24°C 6°C 24°C ~ ~ ~ ~ ~ ~ ~ ~ ~ 1 1 1 1 1 < -20°C < -18°C < -20°C 20 20 20 20 Storage temperature Each unit of apheresis platelets is supplied only only supplied is platelets apheresis of Each unit of the safety ensure to bacteria passing testing after recipients. transfusion Other matters 1 day 1 year 1 year 5 days 5 days 5 days 5 years 35 days 35 days 35 days 24 hours 24 hours Expiration Component Whole blood Packed RBCs Packed Frozen plasmaFrozen Cryoprecipitates PLT Concentrate PLT Apheresis platelets Apheresis Fresh frozen plasma frozen Fresh Washed red blood cells Washed Pre-storage Leukocyte-Pre-storage Deglyceride Frozen RBC Deglyceride Frozen Leukocyte-Reduced RBC Reduced Apheresis Platelet Reduced Apheresis White blood cell concentrate White The preservation time, temperature, and material cost for each final product are listed in the table below: in the table listed are each final product for cost material and temperature, time, preservation The Each qualified component needs to be labeled and be needs to labeled and Each qualified component then are These items baskets. in blue placed neatly different to according in the warehouse managed conditions. temperature

OUR PERFORMANCE 28 OUR PERFORMANCE 29 Meanwhile, each blood center has has blood each center Meanwhile, Blood supplies are currently classified into classifiedinto currently are Blood supplies The blood supplies of each blood center are are each blood of center bloodThe supplies 24 hours/day. hospitals to available established a list of blood donors filed by red filed red by blood donors of a list established a blood emergency usage If blood cell antigen. for blood will donors occurs, contact the center support. immediate two categories: individual and group. Individual Individual group. and individual categories: two an for the approach to refers blood supply the blood blood center get from to individual blood have neither that in hospitals when patients the for contract a signed group-supply banks nor blood supply Group a bloodneed transfusion. of blood have banks or have that hospitals to refers a blood with contract” signed a “group-supply will the blood center this approach, With center. neededeach to blood products deliver regularly for blood so ready is that storage for hospital time. any at transfusion Each blood storage warehouse of a blood a blood of warehouse Each blood storage Current blood supply channels include five five include channels blood supply Current The management, allocation, and and allocation, management, The Distribution center is equipped with a central temperature temperature a central with equipped is center blood temperature monitor to system monitoring documents, written to addition In 24 hours/day. filed is temperature about information relevant are files in electronic so the records stored and both the blood and accurate, and complete more more and safer are the equipment and items a of vehicle Eachsecure. blood transportation the latest with equipped is center blooddonation whether monitor to system cold-storage/freezing within maintained and stable is the temperature each of the quality so that range the standardized be can ensured. blood item blood centers, 13 blood stations, and several several and 13 blood stations, blood centers, hospitals. proxy-supply transportation of blood for medical use are medical blood use are of for transportation in the based the strictest standards on monitored blood The storage centers. bloodfive donation sets center in each blood donation warehouse temperature, preservation for conditions different blood different for equipment and environment, always are hospitals for Blood supplies products. vans Specific refrigerator 24 hours. available for responsible are blood freezing/storage for blood for of transportation and theallocation bloodmedical bank. usehospital in each Each packaged box of blood items will be put into a into will be blood put items of box Each packaged bags. incubator dedicated They are put in specific transportation vehicles vehicles in specific transportation put They are the of requirement the temperature to according equipment temperature-monitored with blood item each hospital. to be to delivered ready are and Based on the needs of each hospital, final products final products each hospital, Based the needs of on blood-type for labels clear with boxes into put are name. blood item and Each kind of final blood product to be dispatched beto final dispatched Each bloodof kind product one-by- computer will by be checked hospitals to safety. ensure to one The quantity of stored blood in each blood center blood blood each in center stored of quantity The seven than days more at beneeds to maintained storage of seven to days Four concerns. safety for storage of days four while than less lower, a bit are storage a safe is There dangerous. considered is the official on set website up signal display quantity people Blood so that Services Foundation Taiwan of blood each of information the latest check can center. donation

OUR PERFORMANCE 30 OUR PERFORMANCE 31 Regarding blood donor management, we we management, blood donor Regarding blood increase and blood quality improve To We completed the initial study of the Dengue of the initial study completed We Research have analyzed the following repeat-donation repeat-donation the following analyzed have increasing with blood donors of behavior due Taiwan Northern from donate willingness to factors the relevant namely events, significant to the blood of donation the quantity influencing a for construction the corresponding group, quantity, blood model of donation predictive “Encouraging introducing of the effect analysis regular on fixed locations donate to blood donors forecasting the blood to donation weekdays” and sleep quality of the research and model, blood of blood to donation due discomfort blood Regarding Eastern Taiwan. from donors RBCs and packed of returned the quality quality, been has discussed. hospitals by proxy-issued accumulate, bank, we the data to regard With blood of data of amounts huge organize and plan such every that hope so we year donation/supply research. benefit relevant may data All programs. research our continue we safety, the been IRB reviewedby have programs research Review our the IRB of Board), and (Institutional the Ministry by passed has the audit Foundation results Our research Welfare. and Health of blood transfusion recognized by primarily are in academic medical experts published and blood of medical associations at and journals domestically. and both internationally transfusion fever outbreak in Southern Taiwan in 2015, and in 2015, and in SouthernTaiwan outbreak fever in 2016. the ISBT at presented these were reports As medical treatment improves, the demand the demand improves, medical treatment As In line with the health policy of “National the health with policy line “National of In To provide HLA- or HPA-matched platelets. HPA-matched or HLA- provide To blood cells red antigen-negative supply To ) . Mia- E-, c-, (mainly plasma male donor predominately supply To leukocyte (HLA for & HNA) the screening and donors. platelet female among antibodies

Reference laboratory for each subtype of blood clinically provided to to blood provided clinically of subtype each for blood transfusion long-term receiving patients rare. also blood Some quite increases. types are services, cell testing red provide to continue We infection transfusion and reactions, transfusion survey services, cell to red source as well as pre-transfusion for reagents the testing produce blood of clinical safety The screening. antibody the following through ensured is transfusion actions, 1. 2. 3. blood used by the nation”, our Foundation started Foundation our blood the nation”, used by ease 2007 to the in January plasma collectto source blood preparations of lack a of difficult situation original collected The blood plasma’s in Taiwan. plasma the CSL to batch by delivered is material be to furtherfactory into processed in Australia of blood derivatives Four blood derivatives. for albumin 20% Human made: are the TBSF for Immunoglobulin Human Use, Intravenous 250IU Blood Factor Coagulation Use, Intravenous Blood 500IU Coagulation and VIII Concentrate, them, TBSF Among IV Concentrate. Factor is Use Intravenous for Immunoglobulin Human achieve already can and in Taiwan supply the main goal. the 100% supply-to-demand From November 25 to 28, 2019, the Hong 28, 2019, the Hong 25 to November From the visited Korea South from delegation A Exchanges with other nations through through nations other with Exchanges International exchange and training training and exchange International plan Kong Red Cross Blood Transfusion Service Service Blood Transfusion Red Cross Kong to Practice Nurses 2 Advanced dispatched the Taipei to trip study a They made Taiwan. Blood to Center the Kaohsiung Blood and Center and blood donors of the recruitment learnabout collect to blood. the They also thevisited process bloodmobiles fixed site rooms, blood donation sites. blood donation outgoing and themorning on Welfare and MinistryHealth of Sheng- Wei CEO, December TBSF 2019. 16, of Affairs Medical of the Department to went Tang and blood donation of theagenda on report to December 17, 16 to of the afternoon From supply. Blood to Center Taipei our visited the delegation active participation in international conferences conferences international in participation active only not new knowledge relevant acquiring and every for aspect reference important an provides also serve but important as improvement of international of understand better for channels situations. blood components before blood transfusion”, blood transfusion”, before blood components effective blood and transfusion”, “Proper and Practice”. and System Haemovigilance “Taiwan the possibility reduce to help can These concepts blood transfusion, by caused injury patient of hospitalization reduce and recovery, improve blood of the medical so quality costs that further. even be can promoted transfusions Furthermore, to reduce the risk of the of risk reduce to Furthermore, To assist the hospitals in seeking possible in seeking possible the hospitals assist To Blood safety transfusion transfusion-related acute lung injury (TRALI), injury (TRALI), lung acute transfusion-related male-donor-predominant the policy supplying of 11th, July since been has implemented plasma donation apheresis for blood donors 2015. Female screening, the leukocyte pass antibody must donations in the reduction led to has which more blood. Therefore, antibody-positive of In blood our supply. for provided is protection Foundation our at medicaldoctors addition, blood about medical lectures hold actively the advocate to hospital in each transfusion reactions adverse transfusion “Blood of concepts component “Blood procedures”, preventive and leukocytes reduced pre-storage of therapy-usage causes of blood transfusion adverse reactions, reactions, adverse blood transfusion of causes Haemovigilance Taiwan of established had we Society Blood of Transfusion Taiwan with System National (namely hospitals in 2016, which five Veterans Taipei Hospital, University Taiwan Hospital, Eastern Memorial Far GeneralHospital, and Hospital, Memorial Gung Chang Linkou taken the have General Hospital) Tri-Service send notifications to how leaddemonstrating in had hospitals 35 2019, of the year In 2017. since of a total with beennotification, qualified for the expected after is that 3,058 notified cases. It all to expanded gradually the is hospitals system analyze collect will to and we be able in Taiwan, blood better provide patients, blood from data related those issues solve to strategies transfusion to help and transfusion, and bloodto donation safety. blood transfusion improve

OUR PERFORMANCE 32 OUR PERFORMANCE 33 the Hong Kong Red Cross Red Cross Kong the Hong Service Blood Transfusion Blood Taipei visited bloodmobile. Center Our Foundation has used the previous used has the previous Our Foundation malevolent of the prevention strengthen To Information business and network network and business Information security blood donation/supply management information information management blood donation/supply the a decade. Considering than more for system blood donation future of concern and assessment operational internal of services, the improvement our control, quality and blood safety, processes, blood the updated completed have Foundation formally and system information management We 2018. 8th of August at online it launched these computer of take advantage to hope digitalized, paperless, our attain to technologies both operation promote goals to automation and services. blood donor and quality software new blackmail by spread software invite regularly we e-mail, or via webpages To strengthen the interaction and the the and the interaction strengthen To mutual learning between Taiwan and mainland mainland and between Taiwan learning mutual started the “Health has Foundation China, our & blood supply” blood donation of professionals including topics which covers class, training blood collection, blood donors, of recruitment since supply blood composition and testing 2019 in sessions training 1 held We 2015. March Blood China (the Zhejiang from 4 people with course. in the training participated Center) learn some lessons focusing on the recruitment the recruitment on focusing lessons learn some the blood management safety bloodof donors, topics. other and GMP, system, TBSF and and TBSF blood centers Internet Internet / Internet DR site (Disaster Intranet Switch Intranet Recovery Site) VPN VPN The system framework of the LINE the LINE of framework system The (Virtual Private Private (Virtual interactive application platform adopts Gateway Gateway adopts platform application interactive server from the LINE OA Firewall separate to and server to database and management the backstage The information. blood donor of the safety ensure execute can the system backstagse function of all controlled in the range of low risk. In March March In risk. low of thein range allcontrolled domain Directory) web 2016, the AD (Active launched was project setup virtual platform and service the internet integrate and establish to at contents activity of framework management centers. blood donation and Foundation our Network) Intranet Network) mobile WAN Switch Internet Mobile 3G/4G Data VPN Data information infrastructure information Switch Internet Internet production site hospital blood donors Illustration: Our Foundation provides the internet framework for the blood donation/supply the blood donation/supply for framework the internet provides Our Foundation Illustration: of the information transportation, wireless and cable a high-speed internet Via system. site. each blood donation at accurately and quickly be can checked blood donors professional lecturers to give educational training training educational give to lecturers professional center, eachblood allto the donation staff at viral computer of updating daily to addition in protect to hope codes. We software protection blood donors, of the personal information friends in a highly internet and employees, efforts everyone’s through way standardized the personal information by the monitoring and complete increase To committee. management efficiency the and effectiveness network and risk conduct we information, computer of safety information assets on information of assessments are classifications risk The data. and facilities

OUR PERFORMANCE 34 OUR PERFORMANCE 35 The TBSF has not only overcome the the overcome only not has TBSF The collection, recruitment, testing, and component, component, and testing, recruitment, collection, medical services, quality blood supply, addition, In processes. work and management filling forms, appointments, blood online donor operating network hospital and inquiry systems, a build to order In developed. were systems the with in line is meets the needs and that system manpower of lot a invested has times, the TBSF blood this highly automated plan time to and applies and system information management the fully software technologyto upgrade cloud and uses the network devices and hardware and and the workflows digital technology integrate to expected is that services It side. the system from developed this time will the system the enhance in the rigor performance, in work consistency the service and efficiency. control quality the in transferring challenge overwhelming been has that blood donors on information the new to years 40 than more for accumulated the databases also has incorporated but system, in the blood donation scattered originally cloud the era of the country into across centers integration. real virtual and and synchronization the process, the blood the part donation of In the in APPs usedhas the cross-platform TBSF the click a single by import technology to cloud the making the database, into data blood donor's rigorous service and more even work processes devices All high-end information smoother. and Data IDC (Internet placed in the professional are synchronize so to as rooms, computer Center) and stability system improve and backup remote availability. In operation from 1999 to 2018, the original 1999 to from operation In The TBSF's newly customized information information newly customized TBSF's The To ensure computer information security, security, information computer ensure To donation and blood supply system has existed existed has system blood supply and donation software all its a result, As 20 years. nearly for carry to able and longer no were hardware and the face In data. of pieces of millions calculate the digitalin technology and forward the leap of requirements, functional many update need to user its 2015 fully since re-evaluated has the TBSF programming architecture, network requirements, planning and Interviews database. and language, blood of line the entire across carriedout were system was finally launched on August 8, 2018 8, 2018 August on finally was launched system analysis, system of the process undergoing after testing, integration testing, unit writing, program environmental parallel testing, conversion, data training. and education and construction, New system online, building a smart management building a smart management online, system New blood process supply donation the TBSF has not only updated its anti-virus anti-virus its updated only not has the TBSF also established virus codes but software this year (SMG) Gateway Messaging the Symantec filtering in functions the mail strengthen to viruses, When so on. sites, and web malware, as file the system identified is by attached an will the email be to the attachment malware, the system. by deleted automatically all automatic displays and accurately display display accurately and displays all automatic blood donation for blood respective donors to blood donation individual or broadcasts activity will functions be more the future, In invitations. blood the purpose promoting developed of for donations. In order to shorten the waiting time for timefor the waiting shorten to order In you Special system, Zone" the "Donor In also constructed have we the hospitals, For the blood donors, the new Blood Management the new Blood Management the blood donors, appointment an provides System Information Those who service blood making donations. for in appointments blood whole make can donate the system and month, one within advance the donors remind to will take the initiative date. the appointment before 2 days email by can apheresis blood by Thosewho donate if but month, a within appointments 2 make met, not are conditions blood donation your for appointment will your the system suspend blood donation. records, blood donation the previous check can praise of the records date, donation the next the blood even download and recognition, and these All operations of certificate online. donation a personal computer, on only not becan done Now, tablet. or phone mobile your also on but blood services after and and the processes before the closerto and convenient, more are donation and a convenient blood making donation donors, good thing! simple the on platform" operation network a "hospital blood bank the hospital can only Not system. blood required subscribe various directly to also can it but the platform, through products blood as information such in the system answer blood investigation, uses, blood transfusion horizontal This etc. application, consultation blood blood and the hospital's of integration the response improves operations supply of management the making two-way efficiency, It is particularly worth mentioning that that particularly mentioning is worth It The most significant change for blood blood for change significant most The the health questionnaire is designed to be more designed be is to more the health questionnaire blood safety strengthen to is This rigorous. each to reply donor’s linking a by management questionnaire health thein front-end question the control and the blood products of each to in the blood management donors code of suitable not condition any If system. information will the triggered, system is blood donation for trace and the blood donor intercept automatically all according back in the past the blood products a forming the system, set by the conditions to in the network protection monitored completely blood management. safety donors is the high degree of electronization of the of electronization the high is of degree donors the of uploading the simultaneous and process a blood After the database. to data blood donor in key can she or he the logs in system, donor registration the blood donation tablet a through then and questionnaire the health and form a by information personal her or his confirms collection process this data As digital signature. in online be can carried digitizedis and out time in waste do not blood donors advance, filling the form and the registration for waiting not is movement paperless This the spot. on also friendly but environmentally more only can a blood donor in that convenient more or card health insurance her insert or either his his get to ID card her or his on the barcode read information, personal other and name her or replacing time and display the data accelerating for automation with operation the manual human reduce greatly certification to double errors.

OUR PERFORMANCE 36 OUR PERFORMANCE 37 We conduct information asset risk risk asset information conduct We system judges an attachment of an email to be be to email an of attachment an judges system will be attachment the email software, malicious the system. by automatically deleted and equipment information on assessments the possible every control materials and year enhancement The range. risk a low to levels risk a high degree security requires information of As colleagues. all our from cooperation of hold we concept, a correct have everyone must give to training and education all-round annual continue and assessments conduct and lectures security so of that issues, deepento the publicity utilize collect, and colleagues can handle our laws, relevant to according personal information also We norms. internal or orders administrative requesting subcontractors, our to send letters personal on audit on-site conduct them to of the printing for management information them, to outsource we that inspection reports We so far. been found defects have major no and Information the Personal convene also regularly how examine to Committee Management manages center blood each donation effectively is It in a particular year. personal information its the information while strengthening that hoped the also can protect we security management, and blood our donors for information private colleagues. internal To ensure the security of TBSF computer computer the security TBSF of ensure To After the new information system was was system the newinformation After At the beginning of the launch, people people the launch, the beginning of At information system, we need not only to to only need not we system, information but software, the antivirus update continuously Gateway Messaging the Symantec also establish to and malware of the filtering enhance to (SMG) the When URL system. and the email virus from launched, we have installed the information installed the information have we launched, main the TBSF of the Gateway security on system the TBSF each of of points the end office and strengthen so to as Centers Blood Donation the requirements meet securityand information the regulations. of Information security issue is never ending Information may feel a little bit unaccustomed, but in order in order but unaccustomed, bit little a feel may of the supply for quality the overall improve to the efficient through blood blood and products are people technology, cloud and digitalnetwork blood the smart information support to urged a highly create so to as system management and blood donation for efficient mechanism service. supply blood products more rapidly and more reliably. reliably. more and rapidly more blood products efficient more and better provides only not It the also improves but services the hospitals, for medical uses. blood for quality 1999 Award Welfare Public National 1995 Best the2nd Advertising of Mention Honorable Awards Slogan Lives." Blood, Save "Give work: Award-winning 1996 Slogan Best the 3rd Advertising of Medal Bronze Awards are!" who you know I don’t even though you thank “I Reward records "Creator of History" Charity Model Award Model Charity History" of "Creator The 1st National Public Welfare Award Welfare Public National 1st The Gold Medal of Times Advertising Awards in the in the Awards Advertising Times of Gold Medal Corporate Charity category Blood and Chan "Jackie work: Award-winning TV Ad Donation" 1993 1992 1992

OUR PERFORMANCE 38 OUR PERFORMANCE 39 2019 National of (Symbol SNQ certification of The in the National Award Bronze Quality) and Clinical QualityBiotechnology Award. in patients for angel "Guardian Theme: The islands offshore and areas remote Taiwan, southern Blood Center" --Kaohsiung 2018 National of (Symbol SNQ certification of The in the National Award Bronze Quality) and Clinical QualityBiotechnology Award. highly and comprehensive "The Theme: The blood ensure to donor of testing efficientlaboratory in Taiwan" safety transfusion 2017 National of (Symbol SNQ certification of The in the National Award Silver Quality) and Clinical QualityBiotechnology Award. Sufficient and Safe of Pioneer "The Theme: The Blood Supply" 2008 Award Contribution Award Activity Internet Award Vitality Website GDP Distribution facilities licensed by the TFDA. licensed facilities by Distribution GDP GMP manufacturing facilities licensed by the Taiwan Food and Drug Administration (TFDA). Drug Administration and Food the Taiwan licensed facilities by GMP manufacturing ISO 15189 laboratory accreditation. ISO 15189 laboratory The testing laboratories accredited by the Taiwan CDC for syphilis, HIV and HCV. HIV and syphilis, CDC for the Taiwan by accredited laboratories testing The Approval of the Therapeutic Goods Administration (TGA, Australia ) to meet their standards of the of meet their standards ) to Australia (TGA, Goods the Therapeutic Administration of Approval blood quality. Implementation of the ISO 9001 quality system. the ISO 9001 quality of Implementation Approval of the Medicines Control Agency ( MCA, UK ) to meet their standards of the blood of quality. meet their standards UK ) to ( MCA, Agency Control the Medicines of Approval Quality assurance 2018 2012 2012 2010 2006 2001 1999

OUR PERFORMANCE 40 STATISTICS Unit 3,000,000 289,258 274,590 205,139 249,553 264,654 243,093 221,866 232,361 180,342 227,982 152,511 89,976 2,500,000 2,437,157 2,378,044 2,366,061 2,333,467 2,327,594 2,329,618 2,314,197 2,313,016 2,292,414 2,286,164 2,262,452 2,241,603 76,548 2,000,000 Whole blood Whole platelets Apheresis 1,830,739 1,500,000 25,725 1,286,107 667 1,000,000 831,846 429 500,000 454,512 149,337 3,817 0 1. 250ml per unit for whole blood and 500ml counts for 2 units. for 500ml blood counts whole and 1. 250ml for per unit Year 1974 1979 1984 1989 1994 1999 2004 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 Note: Note: 2 units. for dose counts double and platelet apheresis dose for per unit adult 2. Single Annual bloodAnnual collection, 1974-2019

STATISTICS 42 STATISTICS 43 Unit 3,817 Total 149,337 454,941 832,513 1,311,832 1,907,287 2,331,579 2,444,925 2,509,960 2,583,183 2,555,333 2,490,434 2,518,525 2,556,109 2,577,147 2,578,851 2,640,651 2,726,415 - - - 0 0 0 0 64,380 90,965 64,549 Blood Blood Center 106,854 109,368 114,586 115,834 115,266 112,451 110,929 114,474 Hualien 0 31,884 Blood Blood Center 106,237 169,557 252,897 360,060 437,362 420,616 423,333 453,274 434,767 414,876 431,181 423,721 447,145 436,805 437,351 460,636 Kaohsiung 0 0 60,123 Blood Blood Center Tainan 119,179 173,297 257,309 321,441 382,251 389,938 405,553 405,409 401,442 409,314 418,909 421,457 420,428 424,617 426,291 0 24,723 Blood Blood Center 101,219 231,199 252,889 378,516 489,079 487,230 500,298 507,104 504,362 487,170 485,767 498,956 507,973 520,231 536,306 551,889 Taichung 0 0 0 0 Blood Blood Center 161,765 266,497 333,898 326,619 343,531 347,807 343,225 336,853 337,408 355,943 364,244 360,146 373,358 393,568 Hsinchu 3,817 92,730 Blood Blood Taipei Center 187,362 312,578 406,604 553,940 642,945 718,841 738,274 753,611 752,304 737,642 743,926 744,106 771,779 841,241 869,019 894,031 Blood centers 1974 1979 1984 1989 1994 1999 2004 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 1. Total blood collection units: calculated by both whole blood and apheresis collection. apheresis blood both whole and blood calculated by collection units: 1. Total Year Annual bloodAnnual collection 1974-2019 blood by centers, 2 units. for 500ml blood counts whole and 2. 250ml for per unit 2 units. for dose counts double and platelet apheresis dose for per unit adult 3. Single Note: Note: Unit 400,000 44.12% 39.27% 30.28% 34.92% 18.09% 27.88% 16.94% 31.85% 24.40% 17.30% 100% 317,380 350,000 282,296 361,168 300,000 80% Apheresis platelets Apheresis 244,690 55.49% 64.53% 68.03% 214,032 250,000 198,463 65.56% 60% 184,120 181,788 63.84% 61.59% 169,192 62.70% 200,000 162,338 62.04% 58.30% 54.73% 40% 150,000 100,000 20% Platelet concentrate Platelet platelets Leukocyte-reduced apheresis 50,000 1.15% 8.13% 2.43% 3.04% 13.88% 8.27% 27.57% 5.45% 10.04% 18.16% 0 0% 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 Platelet products Platelet Cryoprecipitate Year Year 2.37% 2.41% 2.72% 34.88% 3.57% 48.26% 7.29% 12.75% 4.69% 18.04% 2,000,000 100% 346,198 327,332 286,385 97.63% 97.59% 97.28% Frozen plasma Frozen 96.43% 95.31% 80% 92.71% 248,596 232,299 1,500,000 238,526 194,828 225,980 209,616 87.25% 193,628 81.96% Leukocyte-reduced RBCs 60% 65.12% 1,000,000 1,249,209 1,184,867 1,123,166 40% 993,779 992,591 996,553 988,757 51.74% 1,035,415 1,018,414 1,025,602 500,000 Fresh frozen plasma frozen Fresh 20% Packed RBCs Packed 0 1. 250ml per unit for whole blood and 500ml counts for 2 units. for 500ml blood counts whole and 1. 250ml for per unit 0% 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2 units. for dose counts double and platelet apheresis dose for per unit adult 2. Single 12 units. adults per dose for concentrate 3. Platelet Note: Note: Year Redblood cellproducts Year Annual blood supply, 2010-2019 2010-2019 bloodAnnual supply, Plasma products Plasma

STATISTICS 44 STATISTICS 45 Unit Total Total Blood Blood Blood Blood Center Center Kaohsiung Kaohsiung Blood Blood Blood Blood Center Center Tainan Tainan Blood Blood Blood Blood Center Center Taichung Taichung Blood Blood Blood Blood Center Center Hsinchu Hsinchu Blood Blood Blood Blood Taipei Taipei Center Center 4,928 318 0 42 24 5,312 16,568 11,546 318 9,644 4,928 42 24 0 2,192 0 39,950 380,237 181,350 172,116 204,892 273,874 1,212,469 204,892 273,874 181,350 172,116 380,237 44.15 54.48 48.75 56.44 50.65 49.60 48.75 56.44 50.65 44.15 54.48 299,729 159,582 202,557 176,326 150,563 988,757 299,729 159,582 193,628 36,566 31,682 53,808 42,622 28,950 8,843 1,769 2,712 3,133 3,762 20,219 3,133 3,762 8,843 1,769 2,712 1,131,043 157,213 124,862 158,412 313,674 376,882 18 0 0 18 0 0 60,182 13,937 31,602 26,327 26,580 158,628 60,182 13,937 31,602 26,327 26,580 127,881 49,656 23,985 19,676 15,931 18,633 286,509 109,838 37,922 51,278 42,258 45,213 160,238 51,736 72,464 53,452 23,278 361,168 53,452 23,278 160,238 51,736 72,464 3,972,874 598,174 811,762 632,233 631,203 1,299,502 0.26 0.85 99.75 99.48 99.84 99.49 99.27 99.25 0.41 0.90 1.22 1.30 775,417 346,042 490,531 368,539 403,530 2,384,059 490,531 368,539 403,530 775,417 346,042 9,437 4,511 2,029 3,301 1,032 20,310 3,301 1,032 4,511 2,029 9,437 Blood centers Blood centers Total PR ratio PR Packed RBCs Packed Fresh frozen frozen Fresh plasma plasma Frozen Washed RBCs Washed Leukocyte-reduced RBCs thawed Frozen deglycerolized RBCs Whole blood Whole Subtotal Cryoprecipitate Total units issued units Total WBC concentrate apheresis platelets apheresis Apheresis platelets Apheresis Leukocyte-reduced Platelet concentrate Platelet Rate of components of Rate Rate of whole blood whole of Rate 1. 250ml per unit for whole blood and 500ml counts for 2 units. for 500ml blood counts whole and 1. 250ml for per unit Blood Blood Blood Blood RBCs Plasma Note: Note: 2 units. for dose counts double and platelet apheresis dose for per unit adult 2. Single included. not fractionation for only,plasma medical usage for are issued numbers plasma 3. The ratio=Plasma/RBCs 4. PR 2. Apheresis 1. Whole blood1. Whole Blood issued blood and in 2019 components Total Liter/1,000 population Liter/1,000 Blood Blood Center Hualien Blood Blood Center Kaohsiung Blood Blood Center Tainan Blood Blood Center Taichung Blood Blood Center Hsinchu Blood Blood Taipei Center 24.01 22.48 26.60 28.63 24.97 121,787 95,958 98,039 - 25.09 191,341 84,391 22.48 26.60 591,516 - 7,969,664 3,753,798 4,578,749 3,351,546 3,925,863 28.64 26.51 24.01 23,579,620 - 25.83 - 196,210 88,549 125,071 23.37 27.31 95,623 103,838 7,965,793 3,788,788 4,580,226 3,338,816 3,917,408 24.63 - 609,291 23,591,031 - 7,187,196 3,623,818 4,532,292 3,379,761 3,724,569 1,013,926 23,461,562 4,532,292 3,379,761 3,724,569 1,013,926 7,187,196 3,623,818 25.52 28.63 25.69 24.73 24.73 22.57 165,198 83,228 116,315 22.90 96,395 101,248 581,899 19,516 7,192,687 3,687,412 4,557,494 3,366,498 3,940,509 23,533,780 789,180 22.63 22.97 117,976 95,089 98,853 184,975 81,657 25.33 21.99 25.85 28.28 25.13 578,550 - 7,979,516 3,712,819 4,564,263 3,361,871 3,934,001 - 24.56 28.32 23.18 23,552,470 25.64 - 25.33 24.65 163,347 78,323 113,190 91,759 93,637 25,359 565,613 91,759 93,637 25,359 113,190 163,347 78,323 23,344,213 4,510,598 3,394,334 3,733,713 1,018,477 7,131,766 3,555,325 571,541 93,876 97,458 25,009 112,667 164,463 78,068 22.90 23,392,036 4,517,652 3,388,101 3,728,935 1,017,442 7,160,559 3,579,347 22.03 578,254 95,724 95,492 25,681 114,808 164,554 81,996 25.09 22.97 27.03 21.81 25.08 24.94 24.90 27.71 24.23 26.14 24.58 24.43 166,138 81,744 120,517 90,927 96,025 27,055 582,405 96,025 27,055 120,517 90,927 166,138 81,744 23,138,381 3,745,132 1,032,012 3,499,663 4,477,114 3,409,906 6,974,554 25.17 26.67 25.64 26.22 23.36 26.92 23.82 168,680 81,785 120,913 102,674 93,291 23,202,551 27,168 594,511 3,737,885 1,026,326 3,498,987 4,484,098 3,400,813 7,054,442 23.91 23,261,573 4,496,195 3,397,242 3,734,579 1,021,830 7,086,152 3,525,575 23.37 26.96 23.61 27.43 22.79 27.47 26.41 26.47 27.28 25.62 26.36 25.33 25.08 167,283 80,345 118,749 92,669 98,441 25,880 583,367 92,669 98,441 25,880 118,749 167,283 80,345 ） ） ） ） ） ） ） ） ） ） Blood （Liter （Liter （Liter （Liter （Liter （Liter （Liter （Liter （Liter （Liter centers Item Liter/1,000 population Liter/1,000 Blood collection Population population Liter/1,000 Population population Liter/1,000 Blood collection Population Blood collection Population population Liter/1,000 Blood collection Liter/1,000 population Liter/1,000 Blood collection Population population Liter/1,000 Population population Liter/1,000 Blood collection Population Blood collection Population population Liter/1,000 Blood collection Liter/1,000 population Liter/1,000 Blood collection Population population Liter/1,000 Blood collection Population 1. Mid-year population, data from the ministry from interior. data of population, 1. Mid-year Year 2019 2018 2017 2016 2014 2015 2013 2011 2012 2010 blood. whole 2. 250ml for per unit Note: Note: Whole bloodWhole collection 2010-2019 per population, 1000 head of

STATISTICS 46 STATISTICS 47 Donation Total Blood Blood Center Hualien Blood Blood Center Kaohsiung Blood Blood Center Tainan Blood Blood Center Taichung Blood Blood Center Hsinchu Blood Blood Taipei Center 7.10% 6.86% 7.67% 8.73% 7.53% 7.42% 7.49% 7.15% 6.70% 7.80% 8.58% 7.33% 590,235 256,830 361,137 283,349 288,327 - 7.44% 7,969,664 3,753,798 4,578,749 3,351,546 3,925,863 1,779,878 - 7.41% 6.84% 7.89% 8.45% 7.34% 23,579,620 - - 7.55% 608,656 7,965,793 269,379 7.64% 7.11% 8.00% 8.55% 7.74% 3,788,788 4,580,226 366,544 3,338,816 - 7.77% 3,917,408 285,584 303,388 - 23,591,031 - 1,833,551 7.12% 6.70% 7.64% 8.71% 7.72% 7.55% 7.50% 7.12% 6.70% 7.43% 7.05% 8.26% 8.95% 8.06% 8.18% 7.89% 7.43% 7.05% 7.71% 8.77% 7.59% 7.73% 7.54% 7.09% 6.94% 7,192,687 3,687,412 4,557,494 3,366,498 3,940,509 23,533,780 789,180 7,979,516 3,712,819 4,564,263 3,361,871 3,934,001 23,552,470 - 7.62% 7.30% 8.32% 8.55% 8.37% 8.24% 7.99% 7.30% 8.32% 8.55% 7.62% 7.80% 8.68% 7.47% 7.85% 7.54% 7.21% 6.80% 23,392,036 4,517,652 3,388,101 3,728,935 1,017,442 7,160,559 3,579,347 7.57% 7.28% 8.43% 8.94% 8.82% 8.33% 8.13% 7.57% 7.28% 23,261,573 4,496,195 3,397,242 3,734,579 1,021,830 7,086,152 3,525,575 23,461,562 4,532,292 3,379,761 3,724,569 1,013,926 7,187,196 3,623,818 1,763,008 349,751 293,792 296,706 511,032 253,135 58,592 570,695 248,783 356,189 288,466 288,391 1,752,524 - 6,974,554 3,499,663 4,477,114 3,409,906 3,745,132 1,032,012 23,138,381 3,745,132 1,032,012 3,499,663 4,477,114 3,409,906 6,974,554 23,344,213 4,510,598 3,394,334 3,733,713 1,018,477 7,131,766 3,555,325 1,754,119 345,234 295,028 287,690 509,548 239,797 76,822 7,054,442 3,498,987 4,484,098 3,400,813 3,737,885 1,026,326 23,202,551 3,737,885 1,026,326 3,498,987 4,484,098 3,400,813 7,054,442 1,834,521 371,259 304,184 300,906 526,216 248,420 83,536 1,767,881 349,238 296,569 282,832 509,230 251,630 78,382 531,254 255,439 372,360 291,710 313,490 84,989 1,849,242 313,490 255,439 372,360 291,710 531,254 84,989 1,760,965 351,790 294,771 278,740 513,907 241,765 79,992 534,349 254,731 377,883 303,895 329,804 85,445 1,886,107 329,804 254,731 377,883 303,895 534,349 85,445 Blood centers Item Donation rate Donation Donation rate Donation Donation rate Donation Donation rate Donation Donation rate Donation Population Donation rate Donation Population Donation rate Donation Population Donation rate Donation Population Donation rate Donation Population Blood donation Donation rate Donation Population Blood donation Population Blood donation Population Blood donation Population Blood donation Population Blood donation Blood donation Blood donation Blood donation Blood donation 1. Mid-year population, data from the ministry from interior. data of population, 1. Mid-year Year 2019 2018 2017 2016 2014 2015 2013 2011 2012 2010 included. are donations 2. Both apheresis blood whole and Note: Note: Blood donation by blood centers, 2010-2019 blood by Blood centers, donation 100% Donation Total 608,656 269,379 366,544 285,584 303,388 1,833,551 46.67% 37.49% 43.16% 46.62% 45.06% 39.40% 43.74% 41.37% 36.47% 45.79% % 90% 6.51 4.85 6.60 6.43 7.46 6.43 80% 39,595 13,063 24,208 18,377 22,643 117,886 Apheresis - 2U Apheresis 70% Apheresis 0 % 4.93 4.92 0.87 2.47 2.92 WB 500ml 60% 0 63.53% 62.51% 3,191 7,045 60.60% 30,002 13,248 53,486 58.63% 50% 56.84% Apheresis - 1U Apheresis 56.26% 54.94% 54.21% 53.38% 53.33% % 40.38 41.25 43.96 42.84 44.37 42.27 40% 500ml 245,780 111,126 161,137 122,330 134,605 774,978 WB 250ml 30% Whole blood % 48.18 48.98 48.56 48.26 48.17 48.39 20% 250ml 293,279 131,942 178,008 137,832 146,140 887,201 10% Type 0% Taipei Tainan Subtotal Hsinchu Taichung Kaohsiung Year Blood Center Blood Center Blood Center Blood Center Blood Center Blood 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 centers Types of whole 2010-2019 of blood donation, Types Types of blood donation in 2019 blood of donation Types

STATISTICS 48 STATISTICS 49 Donor Year Total 2019 12.87% 2018 Blood Blood Center 12.62% Kaohsiung 2017 13.88% Blood Blood Center Tainan 2016 14.05% Blood Blood Center Taichung 2015 14.68% 2014 14.31% Blood Blood Center Hsinchu 2013 14.69% Blood Blood Taipei Center 24,069 12,836 16,278 16,465 14,344 83,992 24,069 12,836 41,749 21,068 26,310 22,379 20,962 132,468 22,379 20,962 21,068 26,310 41,749 13.51% 12.20% 12.87% 13.38% 11.82% 12.09% 61.87% 73.57% 68.43% 63.41% 57.65% 60.93% 345,193 157,467 222,671 165,632 171,874 1,029,500 165,632 171,874 157,467 222,671 345,193 2012 15.52% No.(B) No.(C) %(C/B) %(B/A) 2011 15.65% Blood centers ≦24 2010 15.66% Total donors(A) Total Item Age Donors who donated on more than one occasion in this year would be counted as once. as be counted would in this occasion year one than more on who donated Donors First-time donors First-time First-time donors First-time 0% 10% 12% 14% 16% 18% 20% First-time donors in 2019 donors First-time Note: Note: Trends in the rate of first-time donors, 2010-2019 donors, first-time of rate in the Trends Year 2019 83,992 2018 88,661 2017 93,092 2016 96,314 2015 102,452 Donors 2014 100,912 2013 104,090 2012 116,314 2011 117,932 2010 114,319 0 Donor 80,000 100,000 120,000 140,000 160,000 ≤24 age first-time donors, 2010-2019 donors, first-time ≤24 age

STATISTICS 50 STATISTICS 51 Donor Age 603,877 425,630 Total (58.66%) (41.34%) 1,029,500 (100.00%) 1.42 Total 433 878 1,311 >65 (0.10%) (0.13%) Ratio=male/female (0.15%) >65 2.03 89,621 51~65 120,252 209,873 (19.91%) (21.06%) (20.39%) 1.34 51~65 82,728 41~50 140,811 223,539 (23.32%) (19.44%) (21.71%) 1.70 41~50 31~40 162,450 101,678 264,128 (26.90%) (23.89%) (25.66%) Gender age by ratio 1.60 31~40 21~30 140,616 101,452 242,068 (23.29%) (23.84%) (23.51%) 1.39 21~30 ≤20 52,180 56,935 109,115 (8.64%) (13.38%) (10.60%) ≤20 0.92 Age 1 Male Total Both whole blood and apheresis donations are included. are donations Both apheresis blood whole and Female Ratio Gender Distribution of donor by gender and age in 2019 and gender by donor of Distribution Note: Note: Donation Total Donation frequence Donation 1.37 1.51 1.73 1.91 2.05 2.99 1.78 Blood Blood Center Kaohsiung Blood Blood Center Tainan Donation frequence Donation 1.33 1.40 1.55 1.47 1.85 1.53 2.08 1.63 2.24 1.80 3.35 2.26 1.91 1.60 Blood Blood Center Taichung Blood Blood Center Hsinchu Male Female Male Female Male Female Male Female Male Female Male Female Male Female Blood Blood Taipei Center 264,183 134,768 203,261 135,357 119,081 264,183 134,768 203,261 135,357 856,650 1,833,551 46.72% 43.40% 50.03% 55.45% 47.40% 39.25% 285,584 303,388 608,656 269,379 366,544 344,473 134,611 163,283 150,227 184,307 344,473 134,611 163,283 150,227 976,901 53.28% 56.60% 49.97% 44.55% 52.60% 60.75% Age / Gender Age Blood centers Total >65 ≤20 Total 21-30 31-40 41-50 51-65 Mobiles Fixed site Fixed Sites Blood collection in 2019 sites by Donation frequency in 2019 age and gender by Donation

STATISTICS 52 STATISTICS 53 Donation Student (12.00%) 220,039 Industry 425,151 (23.19%) Business 229,408 (12.51%) Government employees & teachers employees Government 135,353 (7.38%) Total 1,833,551 Military 101,081 (5.51%) Agriculture 14,560 (0.79%) Professionals 32,974 (1.80%) Others 244,502 (13.33%) Housekeeping 98,236 (5.36%) Services 332,247 (18.12%) Occupational distribution of donors in 2019 donors of distribution Occupational Participants Total Blood Blood Center Kaohsiung Blood Blood Center Tainan Blood Blood Center Taichung Blood Blood Center Hsinchu Blood Blood Taipei Center 92,912 21,729 56,242 30,906 37,871 239,660 30,906 37,871 21,729 56,242 92,912 2,073,211 341,259 422,786 316,490 291,108 701,568 13.24% 13.30% 7.46% 9.77% 11.10% 11.56% 39,822 13,337 10,381 88,742 8,739 16,463 16,923 1,148 4,368 1,761 2,301 7,345 108 328 984 242 208 98 215 21 33 30 14 117 17,764 2,663 2,767 4,156 1,352 6,826 459 459 45 215 902 39 144 248 46 58 32 73 39 429 185 556 397 344 1,911 397 344 185 556 429 37,547 7,522 30,299 13,711 22,892 111,971 111,971 37,547 13,711 22,892 7,522 30,299 Blood centers Blood pressure too high or too high or Blood pressure too low too high Body temperature Health questionnaire questionnaire Health defferal bodyLow weigh than less count Platelet than more 150,000/ul or 600,000/µL Other abnormalities Tension Blood vessels tooBlood thin vessels Low hemoglobin Low Total participants include deferred participants and successful donations. and participants deferred include participants Total 2 3 5 8 9 6 7 4 1 Reasons of deferral Reasons of Deferred participants Deferred participants Total % Pre-donation donor deferral in 2019 deferral donor Pre-donation Note: Note:

STATISTICS 54 STATISTICS 55 Donation 8,000 7,000 6,107 (0.333%) 6,000 5,000 4,000 3,448 (0.188%) 2,639 (0.144%) 3,000 1,878 (0.102%) 2,000 1,520 (0.083%) 1,125 (0.061%) 1,000 346 (0.019%) 280 (0.015%) 35 (0.002%) 16 (0.009%) 0 TPPA(+) HBsAg(+) Anti-HIV(+) HIV RNA(+) Elevated ALT Elevated Anti-HCV(+) HCV RNA(+) HCV HBV DNA(+) HBV Bacteria culture Only platelet apheresis donations were tested for bacteria culture. for tested were donations apheresis platelet Only Anti-HTLV- I / II Anti-HTLV- 0.85% ： rate Positive Note: Note: Infectious disease bloodInfectious screening for issue in 2019 4.5% 95.5% Donation 0.03% 0.06% 0.02% 7.05% 0.05% 0.56% 0.02% 0.05% 0.02% 0.03% 0.59% 1.66% 34.49% 21.38% Total 82,229 1,751,314 Number 2 4 1 3 1 3 1 2 36 38 451 106 2,205 1,367 4.3% 95.7% Kaohsiung 13,018 Blood Center 290,369 3.8% 96.2% a a a Antibody a a b Tainan a 10,814 Blood Center 274,770 Anti-Jr Anti-LW Anti-Pr Cold agglutinin Other Anti-Jk Anti-Jk3 Anti-Mi Anti-P1 Anti-I/HI Anti-Ku Anti-Di Anti-Wr Anti-Jk 4.3% 95.7% Taichung 0.34% 1.31% 0.95% 0.39% 0.09% 7.41% 0.05% 0.42% 0.00% 5.63% 3.24% 0.00% 0.31% 13.83% 15,713 Blood Center 350,831 Number 0 0 6 3 5.0% 20 27 25 22 84 61 95.0% 360 207 474 884 antigen in 2019 antigen a Hsinchu 13,439 Blood Center 255,939 4.8% 95.2% Taipei 29,245 Blood Center Antibody 579,405 b a a b - + a a Anti-Le Anti-Fy Anti-Fy Anti-C Anti-c Anti-D Anti-E Anti-e Anti-G Anti-M Anti-N Anti-S Anti-s Anti-Le Mi Mi Sample: 6,393 Sample: (0.3%) erythrocyte donations 5,763 Irregular reactive: antibody Detection of donor Mi donor Detection of Irregular erythrocyteIrregular antibody detected in 2019

STATISTICS 56 STATISTICS 57 Donation Donation 69 77 36 13 % 5.92% 26.64% 23.51% 43.93% 100.00% B A AB Para-Bombay Hm Hm Hm Hm O O O O 4 1 3 1 2 7 2 2 1 1 97 10 18 182 Total 488,451 431,051 805,530 108,506 1,833,538 3 el B B B B 2 3 el int A A AB A AB ABx AxB AwB A B(A) AmB cisAB AB subgroups A1B chimera A1B+B chimera 501 2,141 1,942 3,698 8,282 RhD- 0.45% 1 54 741 B subgroups 3 w el B B B 99.55% 486,310 429,109 801,832 108,005 RhD+ 1,825,256 9 3 4 11 33 102 B A O % AB Total A subgroups x 2 3 el m int A A A A A A Blood Group Statistics of ABO subgroups in 2019 ABO subgroups of Statistics Sample amounts are not the same as the total donations , because of the blood drive records but some of them have no testing results. testing no them have of some but the blood records , because of drive donations the total as the same not are amounts Sample Note: Statistics of ABO RhD and of in 2019 Statistics 8 4 2 4 2 2 2 8 4 2 2 4 2 1 3 3 4 1 3 8 12 20 24 24 10 28 14 42 40 50 10 Unit B B B B B A A A A A A A A O O O O O O O O O O O O O AB AB AB AB AB ABO blood groups Blood groups 0 K s(-) Dc- K(-) RzRz Jr(a-) Fy(a-) Di(b-) Lan(-) Jk(a-b-) Lu(a-b-) Fy(a-)s(-) i adult cell i adult p phenotype D(-)Fy(a-b-) para-bombay Rare blood groups Inventory of rare RBCs rare of Inventory

STATISTICS 58 STATISTICS 59 Person % 3.54 36.85 12.53 15.50 14.59 16.98 43 447 152 188 177 206 Total 1,213 0 1 3 34 11 13 62 Technician and researcher and Technician 395 (32.56%) Temporary 29 94 42 48 46 43 302 staff Physician 26 (2.14%) Administrative Administrative 0 55 79 72 65 157 428 staff Nursing Nursing 52 55 44 79 13 395 152 researcher Technician and and Technician Temporary 62 (5.11%) 2 3 4 6 1 26 10 Physician Nursing staff Nursing 428 (35.28%) Total Taipei Tainan Hsinchu Classufucation Taichung Kaohsiung Head office Head Blood Center Blood Center Blood Center Blood Center Blood Center Administrative staff Administrative 302 (24.90%) Blood centers Human Resources in 2019 Resources Human NT Dollar Operational costs Operational 2,047,148,085 (50.03%) Other revenues 14,021,288 (0.32%) Operational revenues Operational 4,223,884,997 (97.56%) Reserves pension for 190,696,480 (4.66%) Donations 68,309,820 (1.58%) Research and development costs development and Research 431,024,523 (10.53%) Other costs 66,546,699 (1.64%) Interests 23,438,519 (0.54%) Social service charge 80,801,031 (1.97%) Personnel costs Personnel 1,033,593,438 (25.26%) Administration costs Administration 242,016,192 (5.91%) 3. Balance after tax：NT$ 237,828,176 3. Balance after ） purchase ：NT$ 100,039,986（Equipments expenditures 4. Capital ：NT$ 4,091,826,448 expenditures 2. Total NT$ 4,329,654,624 ：NT$ 4,329,654,624 incomes 1. Total Incomes and expenditures in 2019 expenditures and Incomes

STATISTICS 60 APPENDIX FAX: 886-6-213-3201 FAX: 886-7-364-1556 FAX: Tainan Blood Center Tainan Central Dist., Road, West 85, Sec. 1, Yongfu No. R.O.C. 700, Taiwan, City Tainan TEL: 886-6-213-1212 Blood Center Kaohsiung Dist., Nanzi Highway, 1837, Gaonan No. R.O.C. 811, Taiwan, City Kaohsiung TEL: 886-7-366-0999 Tainan City, Chiayi City, City, Chiayi City, Executive Region: Tainan County Chiayi Pingtung City, Executive Region: Kaohsiung County Taitung County, Penghus County, FAX: 886-4-2461-3939 FAX: FAX: 886-2-2897-1601 FAX: 886-3-555-0305 FAX: FAX: 886-2-2395-1002 FAX: Blood centers in Taiwan Blood centers Regional office Regional Head office Head Taichung City, Changhwa Changhwa City, Executive Region: Taichung County Yunlin County, Nantou County, No. 1176, Sec. 4, Taiwan Boulevard, Xitun Dist., Dist., Xitun Boulevard, 1176, Sec. 4, Taiwan No. R.O.C. 407, Taiwan, City Taichung TEL: 886-4-2461-2345 Taichung BloodTaichung Center Hsinchu Blood Center Hsinchu 11th Road, Jhubie 8, Lane 215, Guangming No. R.O.C. 302, Taiwan, County Hsinchu City, TEL: 886-3-555-6111 No. 123, Lih-Der Road, Taipei 112, Taiwan, R.O.C. R.O.C. 112, Taiwan, Lih-Der 123, Road, Taipei No. TEL: 886-2-2897-1600 City, Taipei New City, Executive Region: Taipei County, Matsu County, Kinmen City, Keelung County. Yilan County, Hualien Hsinchu County, Executive Region: Taoyuan County Miaoli County, Taipei Blood Center Taipei Taiwan Blood Services Foundation Taiwan R.O.C. 10066, Taiwan, Road, Taipei 3, Nan-Hai 3 FL. No. TEL: 886-2-2351-1600 www.blood.org.tw Website:

APPENDIX 62 APPENDIX 63 Blood centers and stations and Blood centers Published by the Taiwan Blood Services Foundation ©2020 Taiwan Blood Services Foundation 3F, 3, Nanhai Road, Taipei, Taiwan 10066 Tel: +886-2-23511600 Fax:+886-2-23951002 E-mail:[email protected] http://www.blood.org.tw

Printed in Taiwan, July. 2020