Product Name: PAPOL A+B+G Polyclonal Antibody, HRP Conjugated Catalog No. : TAP01-90565R-HRP Intended Use: For Research Use Only. Not for used in diagnostic procedures.

Size 100ul Concentration 1ug/ul ID 10914, 56903, 64895 ISO Type Rabbit IgG Clone N/A Immunogen Range Conjugation HRP Subcellular Locations Cytoplasm, Nucleus, Lumenal

Applications WB, IHC-P Cross Reactive Species Human, Mouse, Rat Source KLH conjugated synthetic peptide derived from human PAPOLA/PAPOLB/PAPOLG Applications with WB(1:100-1000), IHC-P(1:100-500) Dilutions Purification Purified by Protein A. Background Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A)tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-beta plays a critical role in male germ cell production. PAP-beta-deficient transgenic mice display impaired expression of haploid-specific that are necessary for spermatogenesis. The intronless gene encoding human PAP-beta maps to 7p22.3.

Synonyms PAPOL A/B/G; PAP alpha/beta/gamma; PapIII; MGC5378; PAP alpha; PAP beta; PAP gamma; PAP; PAP-alpha; PAP-beta; PAP-gamma; PAPOLA; PAPOLB; PAPOLG; PAPOA_HUMAN; PAPOB_HUMAN; PAPOG_HUMAN; Plap; polyA polymerase alpha; Polynucleotide adenylyltransferase alpha; polyA polymerase beta testis specic; polyA polymerase beta; polynucleotide adenylyltransferase beta; TPAP; Testis-specic polyA polymerase. Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.

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