Space Physiology

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Space Physiology Space Physiology Jay C. Buckey, Jr., M.D. OXFORD UNIVERSITY PRESS SPACE PHYSIOLOGY This page intentionally left blank SPACE PHYSIOLOGY Jay C. Buckey, Jr., M.D. 3 2006 3 Oxford University Press, Inc., publishes works that further Oxford University’s objective of excellence in research, scholarship, and education. Oxford New York Auckland Cape Town Dar es Salaam Hong Kong Karachi Kuala Lumpur Madrid Melbourne Mexico City Nairobi New Delhi Shanghai Taipei Toronto With offi ces in Argentina Austria Brazil Chile Czech Republic France Greece Guatemala Hungary Italy Japan Poland Portugal Singapore South Korea Switzerland Thailand Turkey Ukraine Vietnam Copyright © 2006 by Oxford University Press, Inc. Published by Oxford University Press, Inc. 198 Madison Avenue, New York, New York 10016 www.oup.com Oxford is a registered trademark of Oxford University Press All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of Oxford University Press. Library of Congress Cataloging-in-Publication Data Buckey, Jay C. Space physiology / Jay C. Buckey, Jr. p. cm. Includes bibliographical references. ISBN-13 978-0-19-513725-5 ISBN 0-19-513725-6 1. Space fl ight—Physiological effect—Handbooks, manuals, etc. 2. Space medicine—Handbooks, manuals, etc. [DNLM: 1. Aerospace Medicine—Handbooks. WD 701 B922s 2006] I. Title. RC1150.B83 2006 616.9'80214—dc22 2005013758 The science of medicine is a rapidly changing fi eld. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy do occur. In their efforts to provide information that is accurate and complete, the author and publisher of this work have checked with sources believed to be reliable, and provided information in accordance with the standards accepted at the time of publication. However, in light of the possibility of human error or changes in the practice of medicine, neither the author; nor the publisher; nor any other party who has been involved in the preparation or publication of this work, warrants that the information contained herein is in every respect accurate or complete. Readers are encouraged to confi rm the information contained herein with other reliable sources and are strongly advised to check the product information sheet provided by the pharmaceutical company for each drug they plan to administer. Additionally, the reader should be aware that individuals chosen for spacefl ight are generally healthy. The information contained herein may not be appropriate for individuals with signifi cant medical illnesses. 9 8 7 6 5 4 3 2 1 Printed in the United States of America on acid-free paper To Sarah This page intentionally left blank Foreword Human space exploration to destinations beyond the moon was fi rst envisioned dur- ing the Apollo era. Over the course of a decade the world followed the transition from suborbital missions to witnessing humans walking on the surface of the moon. The rate of technological advancement to enable the lunar missions exceeded any- thing previously seen in history and would be diffi cult to achieve even with today’s resources. While the dream of sending humans to Mars after the Apollo program was not fulfi lled, the experience of the Shuttle, Skylab, NASA-MIR, and International Space Station programs was critical in following the roadmap to Mars fi rst proposed so many years ago. The initial steps on the path to Mars have been from robotic explorers. These planetary rovers have played a critical role in exploring the surface of Mars, helping to provide insight into the central question of the origins, complex- ity, and possible diversity of life within our solar system. Ultimately, though, joint human–robotic missions will be required to answer one of the major scientifi c ques- tions of this millennium: Does life exist elsewhere in outer space? As government agencies have acquired more experience and technical capability to support long-duration spacefl ight in low earth orbit, there has been the exciting emergence of privately funded spacecraft with the potential to make low earth orbit accessible to members of the public. This capability marks an important transition in human spacefl ight. With increased accessibility to low earth orbit, government agen- cies may now shift their focus to extending the capability for human space explora- tion. Developing the technical capability to send humans farther into space and sup- port them on longer duration missions will provide numerous challenges that will be the ultimate test of the technical capabilities of the world’s space-faring nations. The recent NASA vision for space exploration has clearly focused attention on the path to the Moon and Mars. It will be exciting to follow the development of the Crew Exploration Vehicle, the next generation planetary spacesuit, and habitats required to support these missions. Developing the technical capabilities for planetary exploration is only one part of the equation for human missions. Understanding the long-term physiological adapta- tion of humans living for months in microgravitational and partial gravitational envi- ronments will be critical in minimizing the health consequences of these missions and safely returning the exploration crews to Earth. The transition from the force of gravity on Earth to 0 G while traveling to a planetary destination will be followed by a period of living with a different planetary gravitational force (in the case of Mars, approximately one-third of the Earth’s gravity). This process will be reversed when viii FOREWORD the crew returns to Earth. These transitions will cause signifi cant adaptive changes in a number of physiological systems that may make it more diffi cult for the crew to function normally after landing on the planetary surface or back on the Earth. This book provides an excellent overview of the signifi cant biomedical issues associated with sending humans to explore other planets. The chapters discuss all of the relevant physiological changes associated with astronauts adapting to living in 0 G, and recommendations have been made to minimize the deleterious aspects of these changes and optimize the capability of astronauts to quickly transition to performing work after arriving at their destination. Although these recommendations may change as new knowledge and technical capabilities emerge in the future, they focus our current efforts to provide the appropriate support for crews on long-dura- tion missions. The Spirit rover on the surface of Mars took the fi rst picture of the Earth as seen from another planet. The image of the Earth appears as a pale, likely blue, dot on the Martian horizon, making one wonder about the profound behavioral challenges associated with human planetary exploration. The psychosocial issues of long-dura- tion fl ight are an integral component of this text, and the critical behavioral issues are discussed in detail. As we plan for human space exploration beyond low earth orbit, my dream can be summarized in the simple statement: “by the fi ftieth.” In other words, it is a dream to have humans walking again on the surface of the Moon, and possibly on the surface of Mars, by the fi ftieth anniversary of the Apollo 11 lunar landing in 2019. Let us all strive to make this dream reality. Dave Williams NASA Johnson Space Center Houston, Texas Preface The possibility of sending people to Mars no longer resides solely in the realm of science fi ction. Advances in propulsion, power systems, and materials make a Mars mission an extremely challenging, but potentially achievable, goal. One critical part of a Mars mission, or of any long-duration spacefl ight, is keeping the crew healthy and safe. This book outlines the issues that must be addressed to make long-duration space travel successful and provides suggestions on the approaches to use. Mars has long held a special fascination. At the turn of the twentieth century, many thought Mars harbored an old and dying civilization. They speculated that the Martians had resorted to building canals to irrigate their planet and stay alive. This notion, based on astronomer Percival Lowell’s belief that he observed canals on Mars, was eventually thoroughly discredited. But there may have been a grain of truth in it. Mars may once have harbored life, although of a very simple kind. Knowledge about where life can exist on Earth has greatly expanded our willingness to believe that life may exist elsewhere in the universe. On Earth, life has been found in rocks a kilometer below the surface, in hot springs, in salt fl ats, and in the cooling systems of nuclear power plants. The fact that life can arise and survive in so many hostile environments makes it possible to consider that life may exist, or have once existed, on Mars. This makes Mars exploration compelling. Finding life on another planet could show that life on Earth is not unique and that life may exist in many places throughout the universe. Travel to Mars, however, takes a long time. Although there are many possible mis- sion designs and scenarios, the most common ones project a total trip time of 2.5– 3 years. With current technology, the Mars trip needs to take place when the orbits of Earth and Mars are in the proper arrangement to allow for a low energy transfer between orbits. At these times, getting to Mars takes approximately 6 months. To make the return voyage, however, the Mars crew would need to wait until Mars and Earth were back in the right alignment to make a low energy return trip. This would mean a stay on the Martian surface of around a year and a half.
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