Management of Subfertility and Assisted Conception Joint RCOG/BFS meeting Monday 19 – Thursday 22 April 2021 Location: Online

Programme – Monday 19 April

Subfertility and Reproductive Health Course

9.00am Welcome and introduction Dr Raj Mathur, Consultant and Clinical Lead for , Manchester University NHS Foundation Trust

Session I: Epidemiology and female assessment Chair: Dr Raj Mathur

9.10am Setting the scene and overview of infertility Dr Raj Mathur

9.30am Female workup Dr Alka Prakash, Consultant Clinical lead reproductive medicine and , Cambridge University Hospitals NHS Trust

9.50am Q&A

10.00am BREAK

Session II: Male factor infertility Chair: Mrs Uma Gordon, Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery, Consultant Senior Lecturer, University of Bristol

10.10am Management of erectile dysfunction, anejaculation and male reproductive surgery Mr Maj Shabbir, Consultant Urological Surgeon and Honorary Senior Lecturer, Guy’s Hospital, London; Chair BAUS Section of Andrology and Genitourethral Reconstruction

10.30am Semen analysis and sperm function tests Professor Allan Pacey, Professor of Andrology, University of Sheffield Programme – Monday 19 April

10.50am Q&A

11.00am BREAK

11.10am Clinical assessment of male Dr Sarah Martins Da Silva, Consultant Gynaecologist and Honorary Senior Lecturer, Ninewells Hospital, Dundee

11.30am Step wise approach to managing azoospermia Mrs Uma Gordon

11.50am Q&A

12.10pm BREAK

Session III: Ovulatory disorders Chair: Professor Adam Balen, Professor of Reproductive Medicine and Surgery, Leeds Fertility, Seacroft Hospital

1.00pm The diagnosis and management of WHO Type 1 anovulatory infertility Ms Ephia Yasmin

1.20pm The management of anovulatory PCOS Professor Adam Balen

1.40pm Primary ovarian insufficiency Professor Melanie Davies, Consultant Gynaecologist, University College London Hospitals

2.00pm Q&A

2.20pm BREAK

Session IV: Tubal disorders Chair: Mr Mostafa Metwally, Consultant Gynaecologist; Subspecialist Reproductive Medicine and Surgery, Sheffield Teaching Hospitals

2.40pm Assessment of tubal patency Professor YC Cheong, Subspecialist Reproductive Medicine, University of Southampton

3.00pm Surgical management of tubal disorders Mr Mostafa Metwally

3.20pm Unexplained subfertility Mrs Kalpana Reddy, Consultant Gynaecologist, Cotswold Fertility Unit, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham Programme – Monday 19 April

3.40pm Q&A

4.00pm Ferring Pharmaceuticals Symposium - Ovarian stimulation: The big picture Dr Ernesto Bosch, Director of IVI Valencia

4.25pm Q&A

4.35pm CLOSE OF DAY ONE

Programme – Tuesday 20 April

9.00am Welcome Miss Neelam Potdar, Consultant and Honorary Associate Professor, Reproductive Medicine and Surgery, University Hospitals of Leicester NHS Trust

Session V: Surgery for infertility Chair: Dr Ertan Saridogan, Consultant in Reproductive Medicine and Minimal Access Surgery, University College London Hospitals, London

9.10am Endometriosis associated subfertility Dr Ertan Saridogan

9.30am Fibroids and fertility Professor Yacoub Khalaf, Professor of Reproductive Medicine and Surgery, Guy’s and St Thomas’ Hospital and King’s College, London

9.50am Congenital uterine abnormalities Dr Kana Jayaprakasan, Subspecialist and Honorary Associate Professor in Reproductive Medicine and Surgery, Royal Derby Hospital

10.10am Q&A

10.30am BREAK

Session VI: Fertility preservation and psychological factors Chair: Ms Ephia Yasmin

10.50am Male fertility preservation Dr Mathew Tomlinson, Consultant Scientist and Person Responsible (PR), Nottingham University Hospital

11.10am Female fertility preservation Ms Ephia Yasmin

11.30am Psychological factors and subfertility Professor Jacky Boivin, Professor of Health Psychology, Cardiff University

11.50am Q&A

12.10pm BREAK

Session VII: Pregnancy problems Chair: Professor Siobhan Quenby, Professor of , University of Warwick, Coventry

1.00pm Pre-pregnancy problems Ms Johanna Trinder, Consultant in Obstetrics and Maternal Medicine, University Hospitals Bristol

Programme – Tuesday 20 April

1.20pm Early pregnancy problems Miss Janine Elson, Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery, Liverpool Women’s NHS Foundation Trust

1.40pm Recurrent miscarriage Professor Siobhan Quenby, Professor of Obstetrics, University Hospitals Coventry and Warwickshire NHS Trust

2.00pm Q&A

2.20pm BREAK

Session VIII: Endocrinology in infertility Chair: Miss Neelam Potdar

2.40pm Hypogonadal man Dr Richard Quinton, Consultant Endocrinologist, Newcastle Hospitals and University

3.00pm Thyroid and Prolactin disorders in subfertility/early pregnancy Mr Paul Carroll, Consultant Endocrinologist, Guy’s and St Thomas’ NHS Foundation Trust, London

3.20pm Q&A

3.40pm CLOSE OF DAY TWO

Programme – Wednesday 21 April

Assisted Conception Course

9.00am Welcome Mrs Uma Gordon

Session IX: Setting the scene Chair: Mr Stuart Lavery, Divisional Director Women’s and Children’s Services, University College London Hospital

9.10am Ovarian stimulation protocols Dr Sesh K Sunkara, Senior Clinical Lecturer, Consultant Gynaecologist and Subspecialist in Reproductive Medicine, King's Fertility and King's College London

9.30am Gamete and embryos – preparation, culture, cryopreservation Professor Jason Kasraie, Consultant Embryologist and Person Responsible, The Shrewsbury and Telford Hospital NHS Trust

9.50am Factors affecting success rates Mr Stuart Lavery

10.10am Case presentations on challenging situations in ART patients Mr Ian Aird, Unit Director and Person Responsible, Gateshead Fertility Unit, Queen Elizabeth Hospital, Gateshead

10.25am Q&A

10.35am BREAK

Session X: Gamete retrieval Chair: Mr Kevin McEleny, Consultant Urologist, Newcastle Fertility Centre, Newcastle upon Tyne

10.50am Oocyte retrieval and embryo transfer Dr Tarek El Toukhy, Consultant in Reproductive Medicine, Guy’s and St Thomas’s Hospital, London

11.10am Sperm retrieval Mr Kevin McEleny

11.30am Q&A

11.40am BREAK

Programme – Wednesday 21 April

Session XI: ART Chair: Dr Tarek El Toukhy, Consultant in Reproductive Medicine and Surgery, Guy’s and St Thomas’ Hospital NHS Foundation Trust

12.00pm Regulation of ART Dr Andrew Leonard, Senior Inspector, Human Fertilisation and Embryology Authority, London

12.20pm FET regimens and success rates Dr Umesh Acharya, Consultant Reproductive Medicine, Centre for Reproduction and Gynaecology Wales and the West (CRGW), Plymouth

12.40pm Intrauterine insemination Mr Valentine Akande, Consultant Gynaecologist, Bristol Centre For Reproductive Medicine (BCRM), Southmead Hospital

1.00pm Q&A

1.20pm BREAK

Session XII: Genomics and ART Chair: Professor Yacoub Khalaf

2.00pm Genomics and genome editing - what every reproductive medicine specialist needs to know Professor Peter Braude, Chair RCOG Genomics Taskforce, Emeritus Professor of Obstetrics and Gynaecology, King’s College London

2.30pm Current status and role of PGT Professor Dagan Wells, Director, Juno Genetics / University of Oxford

3.00pm Q&A

3.30pm BREAK

3.40pm Cooper Surgical Symposium - Reimagining PGT-A Testing with PGTai 2.0 Plus David Chrimes PhD, Director, Genomics Business Development, CooperSurgical

4.05pm Q&A

4.10pm BREAK

Programme – Wednesday 21 April

4.20pm Merck Symposium - The spectrum of FSH and LH deficiency in controlled ovarian stimulation Dr Alessandro Conforti

4.45pm Q&A

4.55pm CLOSE OF DAY THREE

Programme – Thursday 22 April

9.00am Welcome Dr Raj Mathur, Consultant Gynaecologist and Clinical Lead for Reproductive Medicine and Surgery, Saint Mary’s Hospital, Manchester

Session XIII: IVF risks and implications Chair: Dr Raj Mathur

9.10am OHSS and risks of ART Dr Raj Mathur

9.30am ART and perinatal outcome Professor Abha Maheshwari, Consultant Reproductive Medicine and Surgery, Aberdeen Royal Infirmary

9.50am Follow-up of ART children Dr Julia Kopeika, Consultant Gynaecologist, Subspecialist in Reproductive Medicine, Guys and St Thomas Hospital, London

10.10am Q&A

10.30am BREAK

Session XIV: Controversies Chair: Dr Jane Stewart, Consultant in Reproductive Medicine, Newcastle Hospitals NHS Foundation Trust

10.50am Adjuvant treatment and alternative therapies Ms Jyotsna Pundir, Consultant Gynaecologist, St Bartholomew’s Hospital, London

11.10am Recurrent implantation failure Miss Srividya Seshadri, Consultant Gynaecologist and Sub Specialist in Reproductive Medicine and Surgery, The Centre for Reproductive and Genetic Health, London

11.30am Q&A

11.50am BREAK

Session XV: Support Chair: Ms Kate Brian, Fertility Network UK

12.00pm Patient perspective Ms Kate Brian

12.20pm Role of counselling Ms Angela Pericleous-Smith, Chair, British Infertility Counselling Association (BICA); Specialist Fertility Counsellor, Leeds Fertility

Programme – Thursday 22 April

12.40pm Q&A

1.10pm BREAK

Session XVI Chair: Mrs Uma Gordon

2.10pm Gamete donor recruitment and treatment Dr Jane Stewart

2.30pm When to stop treatment /donor eggs Mr Sam Abdalla, Founder and Consultant, The Lister Fertility Clinic, London

2.50pm Q&A

3.00pm Summary and Close Mrs Uma Gordon