saginata, the solitary enemy? Comment [D1]: Authors please go through the authors’ guidelines in SDI and AJCRS web sites. Authors have totally ignored the reviewers’ suggestions, by just saying ‘thank you’ and ‘we are french speaking people'. Please recheck for spelling and grammar Amine Bachar, Taoufik Elabbassi, Harouna Bonkoukou Abdoulaye, Mohamed Rachid mistakes. At least at this final stage authors are expected to do proper correctios in the manuscript, Lefriyekh othwerwise it will be summarily rejected.

Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Department of General Surgery, University Hospital Center Ibn Rochd, Faculty of Medicine and Roman, 12 pt Formatted: Justified, Line spacing: Double Pharmacy, Hassan II University, Casablanca, Morocco Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt *Corresponding Author: Bachar A, Department of General Surgery, University Hospital Center Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, 12 pt Ibn Rochd, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco, Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, 12 pt

Abstract:

We report the a case of a 62-year-old female patient with no previous history of medical or Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman surgical ailments.history, admitted for gastric adenocarcinoma. Its extension assessmentHer metastatic workup was negative. She received 3had three pre-operative chemotherapy courses Formatted: Font: (Default) Times New Roman and sent was taken up for total gastrectomy. Surgical exploration revealed a resectable gastric Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman tumortumour without hepatic metastasis or peritoneal carcinosiscarcinamatosis. The enterotomy Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman for restore restoration of digestive system continuity lead to objectified the fortuitousan incidental Formatted: Font: (Default) Times New Roman, Italic discovery of a parasite type tænia saginata in the small bowel (Fig.1). The patient was applied Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New ongiven a single dose of 10 mg/kg body weight.praziquantel at a dose of 10mg/kg. Roman, 12 pt Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman Tapeworms are that can live as parasites in the . Taenia Formatted: Font: (Default) Times New Roman, Italic saginata are the intestinal solitary tapeworms for which are the only definitive hosts. She Formatted: Font: (Default) Times New Roman It is found in many areas worldwide, but is most common in areas where consumption of undercooked beef is high. Most people colonized with adult T. saginata are asymptomatic; those Formatted: Font: (Default) Times New Roman, Italic with symptoms complain of mild abdominal discomfort, loss of appetite, or change in stool Formatted: Font: (Default) Times New Roman patternpat-tern. Occasionally segments can enter the appendix, common bile duct, or Formatted: Font: (Default) Times New Roman pancreatic duct and cause obstruction. The length of adult worm is usually 5 m; however, it may reach up to 25 m. Formatted: Font: (Default) Times New Roman

Taenia infection usually is diagnosed by identifying eggs or proglottids in the stool and cellophane- tape perianal swab to detect eggs as early as about three months after infection.

Eosinophilia and elevation of serum IgE may be present. Serological tests are not routinely Formatted: Font: (Default) Times New Roman performed. PCR based methods, are also done providing for definite diagnosis and Formatted: Font: (Default) Times New Roman, 12 pt discrimination. The most complications of are includinginclude abdominal pain, Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman obstruction, inflammation, and perforation of small bowel, appendix, and colon. The treatment is Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New medical by antiparasitic (or dewormers) with Praziquantel typeor in addition to Roman, 12 pt Comment [D2]: surgical intervention in case with complications. Moreover, our 62-year-old patient had both Replace with fresh keywords 4‐8 in numbers in MeSH terms in alphabetical order other than those mentioned in the title. gastric neoplasm and taeniasis Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman Keywords Tapeworms, , dewormers, praziquantel Formatted: Font: (Default) Times New Roman, 12 pt Dewormers, gastric tumour, praziquantel, proglottids, tapeworms, surgical exploration. Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman Comment [D3]: One of the reviewers has suggested to add a brief notes on the life cycle of tinea saginata. This has to be done at least now. Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Introduction Formatted: Font: (Default) Times New Roman, 12 pt Taeniasis in humans is a parasitic infection caused by the tapeworm species Taenia saginata Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New (beef tapeworm), (pork tapeworm), and Taenia asiatica (Asian tapeworm). Roman, Italic Formatted: Font: (Default) Times New Roman Humans can become infected with these tapeworms by eating raw or undercooked beef (T. Formatted: Font: (Default) Times New Roman, Italic saginata) or pork (T. solium and T. asiatica). People with taeniasis may not know they have a Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New tapeworm infection because symptoms are usually mild or non-existent. Taenia solium tapeworm Roman, Italic Formatted: Font: (Default) Times New Roman infections due to ingestion of tinea eggs or proglottids can lead to in brain Formatted: Font: (Default) Times New Roman, Italic (), which is a disease that can cause seizures, so it is important seek treatment. Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, Italic Cysticercosis can occur innother tissues also [1,2](1). Parasitic infections, caused by intestinal Formatted: Font: (Default) Times New Roman helminths and protozoan parasites, are among the most prevalent infections in humans in Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, Italic developing countries [3,4,5,6](2,3). In developed countries, protozoan parasites more commonly Formatted: Font: (Default) Times New Roman cause gastrointestinal infections compared to helminths. Intestinal parasites cause a significant Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman morbidity and mortality in endemic countries [7,8,9,10](4). Taenia saginata are the intestinal Comment [D4]: In text citations of references must be within square brackets before punctuation in the order tapeworms for which humans are the only definitive hosts. An estimated 80 million people are of their first appearance in the main text. Formatted: Font: (Default) Times New Roman colonized with beef or pork tapeworm. Humans become infected by ingesting raw or Formatted: Font: (Default) Times New Roman, 12 pt undercooked infected meat containing cysticerci and also undercooked agriculture products Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New contaminated with eggs or proglottids [11,12](5). Therefore T. saginata is found in many areas Roman, Italic Formatted: Font: (Default) Times New Roman worldwide, but is most common in areas where consumption of undercooked beef or Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman contaminated agriculture products is high [13,14](6,7). In Morocco it is most commonly because Formatted: Font: (Default) Times New Roman, Italic of consumption of under cooked agricultural products [15]. Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman The current case shows T. saginata in a 62-year-old female patient with no previous history of Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman medical or surgical historyconditions, admitted for gastric adenocarcinoma. However, we could Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New not prove this rare coincidence is a ‘casual’ relationship or ‘causal’ relationship even though Roman, 12 pt Formatted: Normal, Justified, Space After: 8 pt, Line spacing: Double, No page break there is literature evidence for the possibility of carcinogenesis effect of cysticercosis due to before, Don't adjust space between Latin and Asian text, Don't adjust space between Asian text and numbers parasite induced immunocompromise especially in elderly patients; moreover, location of the cysticerci does not correspond to the location of the neoplasia [16]. Even more the same patient may have adult worm infestation and cysticercosis in different parts of the body due to ano-oral Formatted: Font: (Default) Times New Roman, 12 pt self-infection. Comment [D5]: Case presentation is too short and incomplete. Authors to give full details of the case as a Case presentation whole including full details of the gastric tumour. Please add imaging, preoperative pictures and histopathology report on the excised specimen. This is mandatory all the more because new points on a fresh angle of 'taeniasis induced neoplasm' has been added We report the case of a 62-year-old female patient with no previous medical or surgical history, now in the manuscript. Authors by themselves should have done these aspects. They can not expect the editorial board to do this. In view of admitted for gastric adenocarcinoma. Its extension AssessmentHer metastatic work up was the rarity of the possible ‘taeniasis induced neoplasm’ on behalf of the editorial board I myself have taken all strenuous efforts to get a negative. She receivedShe had 3three pre-operative chemotherapy courses and sent then was good shape of the manuscript. Formatted: Font: (Default) Times New taken up for total gastrectomy. Surgical exploration revealed a resectable gastric tumor with rest Roman, 12 pt Formatted: Justified, Line spacing: Double of the abdomen being normal.without hepatic metastasis or peritoneal carcinosis. The enterotomy Formatted: Font: (Default) Times New Roman, 12 pt for restoration of digestive system continuity lead to an incidental restore continuity objectified Formatted: Font: (Default) Times New Roman, 12 pt the fortuitous discovery of a parasite type tænia saginatataenia saginata in the small bowel Formatted: Font: (Default) Times New Roman, 12 pt (Fig.1). The patient was treated with a single dose of praziquantel 10 mg/kg.applied on Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New praziquantel at a dose of 10mg/kg. Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Discussion :Discussion: Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Tapeworms are flatworms that can live as parasites in the human gastrointestinal tract. Taenia Formatted: Font: 12 pt, Italic saginata are the intestinal solitary tapeworms for which humans are the only definitive hosts. She Formatted: Font: (Default) Times New Roman, 12 pt, Italic Formatted: Font: (Default) Times New It is found in many areas worldwide, but is most common in areas where consumption of Roman, 12 pt Formatted: Font: (Default) Times New undercooked beef is high. Most people colonized with adult T. saginata are asymptomatic; those Roman, 12 pt Formatted: Font: (Default) Times New with symptoms complain of mild abdominal discomfort, loss of appetite, or change in stool pat- Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto tern. Occasionally segments can enter the appendix, common bile duct, or pancreatic duct and cause obstruction. The length of adult worm is usually 5 m; however, it may reach up to 25 m. Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto Taenia infection usually is diagnosed by identifying eggs or proglottids in the stool and cellophane- tape perianal swab to detect eggs as early as about three months after infection. Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto Eosinophilia and elevation of serum IgE may be present. Serological tests are not routinely performed. PCR based methods, provideproviding definite diagnosis and species discrimination. Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto

The most complications of taeniasis are includinginclude abdominal pain, obstruction, Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto inflammation, and perforation of small bowel, appendix, and colon. The treatment is medical by with antiparasitic (or dewormers) praziquantel type. The current case shows T. saginata in a 62- Formatted: Font: (Default) Times New Roman, 12 pt, Font color: Auto year-old female patient with no previous history of medical or surgical conditions, admitted for gastric adenocarcinoma. However, we could not prove this rare coincidence is a ‘casual’ relationship or ‘causal’ relationship even though there is literature evidence for the possibility of carcinogenesis effect of cysticercosis due to immunocompromise especially in elderly patients; moreover, location of the cysticerci does not correspond to the location of the neoplasia [16].

Even more the same patient may have adult worm infestation and cysticercosis in different parts of the body due to faeco-oral self-infection.

Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Justified, Line spacing: Double Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt

Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, Italic Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Fig.1. Per operate image showing Taenia saginata after enterotomy in the small bowel Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Formatted: Font: (Default) Times New Roman, 12 pt Comment [D6]: References are not up to date. A few more recent references are added and appropriate corrections are made in the introduction and Conclusion discussion sections.

The references should be in Vancouver style. This case reportthe case reports describes T. saginata in 62-year-old female patient with no For full details on this refer to the following link to university of Queensland (http://www.library.uq.edu.au/training/citation previous history of medical or surgical conditionhistory, admitted for gastric adenocarcinoma. /vancouv.pdf)

In text citations of references must be within However, we could not prove this rare coincidence is a ‘casual’ relationship or ‘causal’ square brackets before punctuation in the order of their first appearance in the main text relationship. It is concluded that Taenia infection usually is diagnosed by identifying eggs or References list also must be numbered in the same order within square brackets. proglottids in the stool and cellophane- tape swab to detect eggs as early as about three months The titles of journals should be in italics and abbreviated according to the style used in Index after infection. The most complications of taeniasis include abdominal pain, obstruction, Medicus/NLM journal abbreviation directory.

et al should be used only when the number of inflammation, and perforation of small bowel, appendix, and colon. authors exceeds 6

Formatted: Font: (Default) Times New Roman, 12 pt References Formatted: Font: (Default) Times New Roman, 12 pt

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Automatic segmentation and classification of human intestinal parasites from microscopy images.

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