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What Do We Know About India's Covaxin Vaccine?
FEATURE Tamil Nadu, India COVID-19 VACCINES [email protected] BMJ: first published as 10.1136/bmj.n997 on 20 April 2021. Downloaded from Cite this as: BMJ 2021;373:n997 http://dx.doi.org/10.1136/bmj.n997 What do we know about India’s Covaxin vaccine? Published: 20 April 2021 India has rapidly approved and rolled out Covaxin, its own covid-19 vaccine. Kamala Thiagarajan examines what we know so far. Kamala Thiagarajan freelance journalist Who developed Covaxin? cheapest purchased by any country in the world at 206 rupees per shot for the 5.5 million doses the Covaxin was developed by Indian pharmaceutical government currently has on order. The government company Bharat Biotech in collaboration with the has capped the price of the vaccine sold in the private Indian Council of Medical Research, a government market, with private hospitals able to charge up to funded biomedical research institute, and its 250 rupees.13 subsidiary the National Institute of Virology. Covaxin does not require storage at sub-zero Bharat Biotech has brought to market 16 original temperatures, which would be hard to maintain in vaccines, including for rotavirus, hepatitis B, Zika India’s climate and with the frequent power cuts in virus, and chikungunya.1 The company reportedly rural areas. Covaxin is available in multi-dose vials spent $60-$70m (£43-£50m; €50-€58m) developing and is stable at the 2-8°C that ordinary refrigeration Covaxin.2 can achieve. How does Covaxin work? Bharat Biotech says it has a stockpile of 20 million The vaccine is similar to CoronaVac (the Chinese doses of Covaxin for India and is in the process of vaccine developed by Sinovac)3 in that it uses a manufacturing 700 million doses at its four facilities complete infective SARS-CoV-2 viral particle in two cities by the end of the year. -
0 January to July 2021
0 www.journalsofindia.com January to July 2021 SCIENCE & TECH ............................................................................................................................................................... 6 1. REUSABLE LAUNCH VEHICLE TECHNOLOGY DEMONSTRATION PROGRAMME(RLV-TD) ................................................. 6 2. GAGANYAAN MISSION ..................................................................................................................................................... 6 3. MARS ORBITER MISSION (MOM) ..................................................................................................................................... 6 4. CHANDRAYAAN MISSION................................................................................................................................................. 7 5. SOLAR MISSION ............................................................................................................................................................... 8 6. ARTEMIS ACCORD ............................................................................................................................................................ 9 7. NATIONAL MISSION ON INTERDISCIPLINARY CYBER-PHYSICAL SYSTEM (NMICPS) ....................................................... 10 8. SMART ANTI-AIRFIELD WEAPON (SAAW) ...................................................................................................................... 10 9. AQUAPONICS ................................................................................................................................................................ -
INTERNATIONAL JOURNAL of BUSINESS, MANAGEMENT and ALLIED SCIENCES (IJBMAS) a Peer Reviewed and Refereed Journal
RESEARCH ARTICLE Vol.8.Issue.1.2021 Jan-March. INTERNATIONAL JOURNAL OF BUSINESS, MANAGEMENT AND ALLIED SCIENCES (IJBMAS) A Peer Reviewed and refereed Journal FACTORS INFLUENCING THE ATTITUDE OF TOURISTS TOWARDS INDIAN TOURISM INDUSTRY: A CASE STUDY OF NAGAPATTINAM DISTRICT IN TAMILNADU E.THANGASAMY Assistant Professor in Commerce, Poompuhar College (Autonomous), Melaiyur, Tamil Nadu, India DOI: 10.33329/ijbmas.8.1.18 ABSTRACT Across the globe, there is not even a single country which does not to grow socially and economically. The rate of their growth highly relies on their efficient economic planning and implementation of appropriate policies and programmes. In order to lubricate the wheels of the economy, the acceleration of industrialization becomes inevitable. Obviously, the performance of industrial sectors significantly contributes E.THANGASAMY to the socio-economic development of nation. In the long run, it is a solution for a chronic problem of unemployment which ensures reasonable standard of living of the people. The industrial growth leads to gradual poverty alleviation and also enhances the rate of GDP. Amongst various industries, tourism industry substantially assists the socio-economic developmental process by creating new avenues for employment for the workforce. Needless to say, its performance has, therefore, been drawing the attention of the government, policy makers, and researchers worldwide, owing to its importance in boosting the economic growth and development. On account of its potential and scope, there have been researches on this front being undertaken globally for framing suitable policies in time. India, amongst the developing countries, is not an exception. Rather, such researches are constantly being carried out by the researchers and the policies are being framed and implemented in the country. -
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6 < %()(=#%% 53%7==,>3='$()6(=#%% (#-'>3='$()6(=#%% $'()"*$+&,- %( !"# $$%& 2(*3-% (566)(37)% 3 0 4 $5 3 $1 2 0 .8 9 8 ++0 0 .:; . !" . / 01 $ %'( $) '# *' it for the last eight to nine notable achievements to its months, “where is the UN in name in the 75 years of its aking a strong case for a this joint fight. Where is the experience, including the pre- Msignificant role for India effective response.” vention of a third world war, in the United Nations, Prime Focussing on a more “we can’t deny terrorist attacks 0 Minister Narendra Modi on prominent role for India in the shook the world”. Saturday stressed the need for UN and fight against corona, “We have successfully ne of the oldest partners changes in the international the Prime Minister avoided avoided a third world war but Oof the BJP — the body and questioned its posi- making any reference to ongo- we cannot deny many wars Shiromani Akali Dal — which tion in fighting the coron- ing tension at the Line of happened, many civil wars has been with it through thick avirus pandemic. Actual Control (LAC) and happened. Terrorist attack and thin for decades, finally He also assured the global frosty ties with Pakistan in his shook the world. Blood was quit the National Democratic Q community that India will pro- 20-minute speech. He also did spilled. Those were killed were Alliance (NDA) on Saturday, vide corona vaccine to the not respond to Pakistan Prime like you and me. Children left signaling a complete political world as it is the world’s biggest Minister Imran Khan’s remarks the world prematurely,” he said. -
COVID-19 Vaccines Update Supplement Week Of: 5Th April, 2021
CARPHA UPDATE FOR Incident Manager / SITUATION REPORT COVID-19 Vaccines Update Supplement Week of: 5th April, 2021 I. Overview of Development and Regulatory Approvals: • 85 candidate vaccines are in clinical development: 16 in Phase 3 trials, and 4 in Phase 4 trials – see Figure in CARPHA COVID-19 Vaccine Regulatory Tracker (Phases tab). • 13 vaccines have received regulatory approvals in various countries, and 16 vaccines are at various stages of engagement with WHO for emergency use listing (EUL). • 4 vaccines have been approved by WHO for Emergency Use Listing: Pfizer-BioNTech’s vaccine: COMIRNATY®, AstraZeneca-SK Bio, AstraZeneca-SII (Covishield), and Janssen-Cilag. • 4 additional vaccines are expected to be approved by WHO in April – Tables 1 and 3. • There are 3 additional vaccines being considered by WHO but these are at the stage of submitting expressions of interest: Bharat Biotech, Clover Biopharmaceuticals-GSK + Dynavax, and BioCubaFarma (Cuba). • The WHO Strategic Advisory Group of Experts on Immunization (SAGE) interim recommendations and background documents are available for vaccines by: Moderna, Pfizer-BioNTech, AstraZeneca-Oxford and Janssen-Cilag at SAGE Interim Guidance. The recommendations provide guidance on the use the vaccines, including use in various groups. • Reports of rare clotting events among vaccinees continue to be assessed by various regulators. The EU's European Medicines Agency (EMA) has stated that there was no evidence to support decisions by regulators to restrict the use of Oxford-AstraZeneca vaccines in some age groups. The WHO maintains that the benefit-risk balance of the vaccine remains favorable. • CARPHA has shared its COVID-19 vaccine regulatory tracker with Member States for viewing as updates are made. -
V.3 1/25/2021 COVID-19 Vaccine FAQ Sheet
COVID-19 Vaccine FAQ Sheet (updated 1/25/2021) The AST has received queries from transplant professionals and the community regarding the COVID-19 vaccine. The following FAQ was developed to relay information on the current state of knowledge. This document is subject to change and will be updated frequently as new information or data becomes available. What kinds of vaccines are available or under development to prevent COVID-19? There are currently several vaccine candidates in use or under development. In the United States, the Government is supporting six separate vaccine candidates. Several other vaccines are also undergoing development outside of the United States government sponsorship and further information can be found here: • NYTimes Coronavirus Vaccine Tracker: https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine- tracker.html • Washington Post Vaccine Tracker: https://www.washingtonpost.com/graphics/2020/health/covid-vaccine-update- coronavirus/ The types of vaccines are as follows (January 25, 2021) 1: Table 1: Vaccines Under Development Vaccine Type Compound Name Clinical Trial Notes [Sponsor] Phase mRNA mRNA-1273 Phase 3 Emergency use in [Moderna] U.S., E.U., other countries Approved in Canada BNT162b2 [Pfizer] Phase 2/3 Emergency use in U.S., E.U., other countries Also approved in Canada and other countries Replication- AZD1222 Phase 2/3 Emergency use in defective [AstraZeneca] Britain, India, other adenoviral vector countries (not U.S.) Ad26.COV2.S Phase 3 [Janssen] v.3 1/25/2021 Recombinant- NVX-CoV2373 Phase 3 subunit-adjuvanted [Novavax] protein Recombinant SARS- Phase 1/2 CoV-2 Protein Antigen + AS03 Adjuvant [Sanofi Pasteur/GSK] Inactivated CoVaxin [Bharat Phase 3 Emergency Use in coronavirus Biotech] India BBIBP-CorV Phase 3 Approved China, [Sinopharm] Bahrain, UAE; Emergency use elsewhere (not U.S.) Both of the mRNA SARS-CoV-2 vaccines (Moderna, Pfizer) have been approved by Emergency Use Authorization by the U.S. -
COVID-19 Vaccination Programme: Information for Healthcare Practitioners
COVID-19 vaccination programme Information for healthcare practitioners Republished 6 August 2021 Version 3.10 1 COVID-19 vaccination programme: Information for healthcare practitioners Document information This document was originally published provisionally, ahead of authorisation of any COVID-19 vaccine in the UK, to provide information to those involved in the COVID-19 national vaccination programme before it began in December 2020. Following authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines and Healthcare products Regulatory Agency being given to the COVID-19 Vaccine Pfizer BioNTech on 2 December 2020, the COVID-19 Vaccine AstraZeneca on 30 December 2020 and the COVID-19 Vaccine Moderna on 8 January 2021, this document has been updated to provide specific information about the storage and preparation of these vaccines. Information about any other COVID-19 vaccines which are given regulatory approval will be added when this occurs. The information in this document was correct at time of publication. As COVID-19 is an evolving disease, much is still being learned about both the disease and the vaccines which have been developed to prevent it. For this reason, some information may change. Updates will be made to this document as new information becomes available. Please use the online version to ensure you are accessing the latest version. 2 COVID-19 vaccination programme: Information for healthcare practitioners Document revision information Version Details Date number 1.0 Document created 27 November 2020 2.0 Vaccine specific information about the COVID-19 mRNA 4 Vaccine BNT162b2 (Pfizer BioNTech) added December 2020 2.1 1. -
Bharat Biotech Inks Licensing Deal with Washington University School of Medicine in St
Bharat Biotech Inks Licensing Deal with Washington University School of Medicine in St. Louis to advance COVID-19 Intranasal Vaccine Technology Hyderabad, India, 23 September 2020: Vaccine Innovator, Bharat Biotech announces today, a licensing agreement with Washington University School of Medicine in St. Louis for a novel chimp- adenovirus, single dose intranasal vaccine for COVID-19. Bharat Biotech owns the rights to distribute the vaccine in all markets except USA, Japan and Europe. While the Phase I trials will take place in Saint Louis University’s Vaccine & Treatment Evaluation Unit, Bharat Biotech, upon obtaining the required regulatory approval, will pursue further stages of clinical trials in India and undertake large scale manufacture of the vaccine at its GMP facility located in Genome Valley, Hyderabad. We are proud to collaborate on this innovative vaccine. We envision that we will scale this vaccine to 1 billion doses, translating to 1 billion individuals vaccinated receiving a single-dose regimen. An intranasal vaccine will not only be simple to administer but reduce the use of medical consumables such as needles, syringes, etc., significantly impacting the overall cost of a vaccination drive. Our experience in viral vaccines, manufacturing capabilities, and distribution continue to be our strong suit in ensuring safe, efficacious, and affordable vaccines. It is prudent for Bharat to be involved in diverse but tenable projects to provide a much-needed vaccine against COVID-19 reaches all citizens of the world.” Dr. Krishna Ella, Chairman and Managing Director of Bharat Biotech, stated. This intranasal vaccine candidate has shown unprecedented levels of protection in mice studies; the technology and data having been recently published in the prestigious scientific journal Cell and in an editorial in Nature. -
Vaccine Matri: a New Way of Diplomacy
AN EXPLORATORY STUDY OF ROLE OF INDIA IN VACCINE DIPLOMACY FOR COVID-19 PANDEMIC ERA Turkish Online Journal of Qualitative Inquiry (TOJQI) Volume 12, Issue 3, June 2021:652- 665 Research Article An Exploratory Study Of Role Of India In Vaccine Diplomacy For Covid-19 Pandemic Era Dr. Saroj Choudhary1, Dr Sanjiv Singh Bhadauria2, Mr Abhinav Upadhyay3, Dr Sandeep Kulshrestha4 Abstract Coronavirus is spread in end of December, 2019 in Wuhan and in March, 2020 World Health Organization declared it as a pandemic. Coronavirus affect world in many ways like socially, economically and in many other. In early January, 2021 India make their vaccine and not only vaccinated their own people but also help other countries and provide vaccine to their neighbouring countries on grant and commercial basis and this will help India to make their reputation in world platform. In this paper, Vaccine Maîtri an initiative by India to provide vaccine to their neighbouring countries and also other needy countries and how this will enhance the image of India in world stage. Keywords: Coronavirus; COVID-19; vaccine maîtri; vaccine; India;government; WHO. VACCINE MATRI: A NEW WAY OF DIPLOMACY COVID-19 is a major global public health challenge, and in many countries it has created a serious social, economic, and political crisis. The numbers involved are staggering, whether they refer to infection and death, the rate of public health measures such as travel restrictions, or the economic consequences of unemployment and public sector spending. All economies are placed in drug-induced comas, the complex public health systems have become increasingly prevalent in levels of public adherence or surprising disobedience, and health care systems and provinces are being tested by many who have never seen it. -
Announcement on Procurement Process
Announcement on Procurement Process During the past few weeks, there have been reports in the media at large misrepresenting the procurement process of COVAXIN®, in Brazil and other countries. We wish to provide the following clarification - ∙ The procurement process for COVID-19 vaccines and several vaccines for routine immunization follow a common process which is widely accepted, and established in Industry ∙ Based on a country’s requirement, the company receives a letter of intent (or MOU) for procurement ∙ The company then proceeds to apply for emergency use authorization (EUA) in the respective country ∙ Once EUA is received, the Ministry of Health (MOH) would proceed to place a firm order by releasing a purchase order, with the required initial quantities. In several countries, MOHs have placed orders for procurement prior to the approval of vaccines such as USA, EU, India, etc. However, procurement happens only post EUA. ● In order to secure a firm Purchase Order from the country, the company proceeds to raise a Pro Forma Invoice to the MOH, towards the supply of vaccine ● Based on the invoice, the MOH pays the amount in advance ● Once the payment is received, the company proceeds to supply the agreed quantities and within the agreed timelines ● In the specific case of procurement of COVAXIN® by MOH Brazil, since the first meetings with MOH Brazil during Nov 2020, until 29th of June 2021, a step-by-step approach has been followed towards contracts, and regulatory approvals, during this ~ 8 long month-long process. On 4th June 2021, ANVISA authorized the exceptional import of the Covaxin vaccine by the Ministry of Health for distribution and Use Under Controlled Conditions”. -
District Legal Services Authority, Nagapattinam List of Selected PLV's SL.No
District Legal Services Authority, Nagapattinam List of Selected PLV's SL.No. Name of the Applicant Place S. Akilan, S/o. Chandrasekaran, 1 2/123, Metu Street, Nagapattinam Vergudi, Orathur (Post), Nagapattinam District - S. Allirani, 2 W/o. R. Selvakumar, Nagapattinam 21/18, V.O.C. Street, Nagapattinam. B. Amuthan Parthasarathi, S/o. Baskaran 1, 3 Nagapattinam Sattayappar Keezha Veethi, Nagapattinam - 611 001. A. Dharani, D/o. U. Archunan, 4 Nagapattinam 32, Pachai Pillayar Kovil Street, Velippalayam, Nagapattinam. K. Malathi, 5 D/o.D/ Kumarasamy,K NNagapattinamtti Keelkudi (Street), Thirukuvalai. R. Renuka, W/o. Rajeshkrishna, Karukanni 6 Nagapattinam (Post), North Street, Mahizhi, Nagapattinam District. A. Sakthipriya, W/o. J. Ayyappan, 1/232, Lelin Nagar, 7 Nagapattinam Etugudi (Post), Thirukuvalai (Taluk), Nagapattinam District - 610 204. L. Sujith, S/o. S. Lelin Kumar, 8 2/39, South Street, Nagapattinam Vergudi, Orathur (Aathidal), Nagapattinam District. A. Vanitha, W/o. Annadurai, 9 3/32, Sikkal Pathu, Nagapattinam Orathur (Post), Nagapattinam District - Tmt.R.Vinoothini, 10 W/o Sekar, Metubangalow, Nagapattinam Kadembadi, Nagapattinam. N.Mohanraj S/o S.Nagarajan 11 2.57, Vadakudi Pakuthayam, Nagapattinam Nagoor(Po), Nagapattinam District 611002 J.Arulmary D/o. M.Jaganathan, 12 2/23 Kalini Street, Nagapattinam Ettukudi(Po), Thirukuvalai (taluk), Nagapattinam District R. Anupriya D/o. M. Rahupathi, 21, Main Road, 13 Vedaranyam Pirichimoolai (Post), Vedaranyam Taluk, Nagapattinam District. V. Marimuthu, S/o. Vairakannu, Kumarankadu, 14 Vedaranyam Agasthiyan Palli(Post), Vedaranyam. R. Subhash Aravind, S/o. V. Rajendran, 7, Pillayar Kovil 15 Street, Pirichimoolai, Vedaranyam Vedaranyam (Taluk), Nagapattinam District -614 712 S. Vasantha Sithravel, W/o. Sithravel, 16 Vedaranyam 2/243, Vadakadu, Karuppampulam - 614 707 P.Lalitha, W/o. -
Nataraja Statue in Siva Temple at Kuthalam Taluk
© 2021 JETIR March 2021, Volume 8, Issue 3 www.jetir.org (ISSN-2349-5162) NATARAJA STATUE IN SIVA TEMPLE AT KUTHALAM TALUK *R. SANTHI & **Dr. R. UDAIACHANDRAN *Research Scholar, Department of History, Annamalai University, Annamalai Nagar. **Associate Professor, Department History, Annamalai University, Annamalai Nagar. ABSTRACT During the sangam age the country was ruled by the Cheras the Cholas and the Pandyas and the Tamil country Kuthalam is one of the most ancient and most celebrated temples in Tamil Nadu. It is great religious as well as historic and cultural significance. Kuthlaam is associated with Nataraja or Siva in his Anandatandava pose the cosmic dance of bliss. Chola Statue - Tamil literature – Tirumular – Tirumanthiram – Tiruvaci – Ohm – Si – va - ya – na – ma – rhythmic 23 numbers. The word kovil or temple in the Tamil saivite tradition refers to none other than the Kuthalam in around temples are Thirumanachery and Thiruvelvikudi this temple built by later chola temples. Key Words: Pandyas, Tirumular, Kuthalam Udhvedhiswarar, Nataraja. Introduction Art can generally be classified in to two types on the basis of its characteristics the one static and the other plastic. Dance and music are plastic while architecture is static, time and space are also the basis in categorizing the art into different classes. Classified into three major division i.e. the art in time, the art in space and art in time and space. Of these the sculpture comes under the static art which depends upon time and space.1 Sculpturing is one of the oldest and most widespread arts of the world. It may broadly be defined as the art of carving.