UPB1 Antibody Cat. No.: 29-755

UPB1 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Arabidopsis, C. elegans, Dog, Drosophila, Human, Mouse, Rat, Zebrafish

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human UPB1.

TESTED APPLICATIONS: ELISA, WB

UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody APPLICATIONS: can be used for detection of UPB1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate

PREDICTED MOLECULAR 42 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by protein A chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

October 2, 2021 1 https://www.prosci-inc.com/upb1-antibody-29-755.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store UPB1 STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: UPB1

ALTERNATE NAMES: UPB1, BUP1

ACCESSION NO.: NP_057411

PROTEIN GI NO.: 7706509

GENE ID: 51733

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases and are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological BACKGROUND: activityThis encodes a protein that belongs to the CN hydrolase family. Beta- ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta- ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

REFERENCES: 1) van (2004) Hum. Mol. Genet. 13 (22), 2793-2801.

ANTIBODIES FOR RESEARCH USE ONLY.

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