UPB1 Antibody Cat. No.: 29-755
UPB1 Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Arabidopsis, C. elegans, Dog, Drosophila, Human, Mouse, Rat, Zebrafish
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human UPB1.
TESTED APPLICATIONS: ELISA, WB
UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody APPLICATIONS: can be used for detection of UPB1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate
PREDICTED MOLECULAR 42 kDa WEIGHT:
Properties
PURIFICATION: Antibody is purified by protein A chromatography method.
CLONALITY: Polyclonal
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
October 2, 2021 1 https://www.prosci-inc.com/upb1-antibody-29-755.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.
CONCENTRATION: batch dependent
For short periods of storage (days) store at 4˚C. For longer periods of storage, store UPB1 STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
OFFICIAL SYMBOL: UPB1
ALTERNATE NAMES: UPB1, BUP1
ACCESSION NO.: NP_057411
PROTEIN GI NO.: 7706509
GENE ID: 51733
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological BACKGROUND: activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta- ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta- ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
REFERENCES: 1) van (2004) Hum. Mol. Genet. 13 (22), 2793-2801.
ANTIBODIES FOR RESEARCH USE ONLY.
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