Anti-CEP72 Polyclonal Antibody Cat: K008658P Summary:

【Product name】: Anti-CEP72 antibody 【Source】: Rabbit

【Isotype】: IgG 【Species reactivity】: Human Mouse

【Swiss Prot】: Q9P209 【 ID】: 55722

【Calculated】: MW:72kDa 【Observed】: MW:50kDa

【Purification】: Affinity purification

【Tested applications】: WB IHC

【Recommended dilution】: WB 1:1000-3000. IHC 1:25-100

【WB Positive sample】: Jurkat

【IHC Positive sample】: Human esophageal cancer and Human liver cancer

【Subcellular location】: Cytoplasm

【Immunogen】: Recombinant of human CEP72

【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background: are the major -organizing centers of mammalian cells. They are composed of a pair and surrounding microtubule-nucleating material termed (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. CEP72 (centrosomal protein 72kDa) is a 647 amino acid protein that localizes to the centrosome and centrosome-surrounding particles throughout the cell cycle. Involved in the recruitment of key centrosomal to the centrosome, CEP72 provides centrosomal microtubule-nucleation activity on the Tubulin ring complexes and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. CEP72 exists as two alternatively spliced isoforms.

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Western blot analysis with CEP72 antibody Immunohistochemistry of paraffin-embedded diluted at 1:2000;Lane: Jurkat Human esophageal cancer with CEP72 antibody diluted at 1:40

Immunohistochemistry of paraffin-embedded Human liver cancer with CEP72 antibody diluted at 1:40

Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information