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The Effectiveness of Disease and Case Management for People with Diabetes a Systematic Review Susan L

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The Effectiveness of Disease and Case Management for People with Diabetes a Systematic Review Susan L The Effectiveness of Disease and Case Management for People with Diabetes A Systematic Review Susan L. Norris, MD, MPH, Phyllis J. Nichols, MPH, Carl J. Caspersen, PhD, MPH, Russell E. Glasgow, PhD, Michael M. Engelgau, MD, MSc, Leonard Jack Jr, PhD, MSc, George Isham, MD, Susan R. Snyder, PhD, Vilma G. Carande-Kulis, PhD, Sanford Garfield, PhD, Peter Briss, MD, David McCulloch, MD, and the Task Force on Community Preventive Services Overview: This report presents the results of a systematic review of the effectiveness and economic efficiency of disease management and case management for people with diabetes and forms the basis for recommendations by the Task Force on Community Preventive Services on the use of these two interventions. Evidence supports the effectiveness of disease management on glycemic control; on screening for diabetic retinopathy, foot lesions and peripheral neuropathy, and proteinuria; and on the monitoring of lipid concentrations. This evidence is applicable to adults with diabetes in managed care organizations and community clinics in the United States and Europe. Case management is effective in improving both glycemic control and provider monitoring of glycemic control. This evidence is applicable primarily in the U.S. managed care setting for adults with type 2 diabetes. Case management is effective both when delivered in conjunction with disease management and when delivered with one or more additional educational, reminder, or support interventions. Medical Subject Headings (MeSH): community health services, diabetes mellitus, evidence- based medicine, preventive health services, public health practice, review literature (Am J Prev Med 2002;22(4S):15–38) © 2002 American Journal of Preventive Medicine Introduction blindness in adults aged 20 to 74 years, and it is also the leading cause of end-stage renal disease, accounting for iabetes mellitus (diabetes) is a prevalent, costly about 40% of new cases. Neuropathy is also a major condition that causes significant morbidity and problem, as 60% to 70% of people with diabetes have mortality. In the United States, 15.7 million D this condition, and more than half of lower limb people (5.9% of the total population) have diabetes, of whom 5.4 million are undiagnosed.1 In 1997 alone, amputations occur among people with diabetes. Fi- 789,000 new cases were diagnosed.1 Moreover, accord- nally, the rate of pregnancies resulting in death of the ing to death certificate data, diabetes is the seventh newborn is twice as high among women with diabetes 1 leading cause of death in the United States.1 Mortality than among those without this disorder. is primarily related to heart disease: adults with diabetes Consistent with its extraordinary effect on the health have death rates from heart disease about 2 to 4 times of Americans, the costs of diabetes to the U.S. health- higher than those without diabetes.1 In addition, the care system are enormous: total (direct and indirect) 2 3 risk of stroke is 2 to 4 times higher in people with costs were estimated at $98 billion in 1997. Selby et al. diabetes. Diabetes is the leading cause of new cases of calculated that per-person expenditures for members of a managed care organization with diabetes were 2.4 From the Division of Diabetes Translation, National Center for times higher than for those without diabetes. Thirty- Chronic Disease Prevention and Health Promotion (Norris, Nichols, eight percent of the total excess costs was spent on Caspersen, Engelau, Jack), and Epidemiology Program Office (Sny- treating long-term complications, particularly coronary der, Carande-Kulis, Briss), Centers for Disease Control and Preven- tion, Atlanta, Georgia; AMC Cancer Research Center (Glasgow), heart disease. Denver, Colorado; HealthPartners (Isham), Minneapolis, Minnesota; Traditionally, healthcare delivery involves individual Diabetes Program Branch, National Institute of Diabetes and Diges- tive and Kidney Diseases, National Institutes of Health (Garfield), providers reacting to patient-initiated complaints and Bethesda, Maryland; and Group Health Cooperative of Puget Sound visits. Care is frequently fragmented, disorganized, du- (McCulloch), Seattle, Washington plicative, and focused on managing established disease Address correspondence and reprint requests to: Susan L. Norris, MD, MPH, Centers for Disease Control and Prevention, MS K-10, and complications. Providers practice what they have 4770 Buford Highway NE, Atlanta, GA 30341. E-mail: [email protected]. been taught and what their anecdotal experiences have Am J Prev Med 2002;22(4S) 0749-3797/02/$–see front matter 15 © 2002 American Journal of Preventive Medicine • Published by Elsevier Science Inc. PII S0746-3797(02)00423-3 led them to believe is effective. The goals are generally The Guide to Community Preventive Services short term, such as pain control or avoidance of The systematic reviews in this report represent the work hospital admission. Management is provider-directed of the independent, nonfederal Task Force on Com- and focuses on pharmacologic and technologic inter- munity Preventive Services (the Task Force). The Task ventions, with little attention to patient self-manage- Force is developing the Guide to Community Preventive ment behaviors or provider–patient interactions.4 Services (the Community Guide) with the support of the Traditional methods of healthcare delivery do not U.S. Department of Health and Human Services adequately address the needs of individual people or (DHHS) and in collaboration with public and private populations with diabetes. For example, in a survey of partners. The Centers for Disease Control and Preven- the care received by patients of primary care providers, tion (CDC) provides staff support to the Task Force to people with diabetes were receiving only 64% to 74% of develop the Community Guide. A special supplement to the services recommended by the American Diabetes the American Journal of Preventive Medicine, “Introducing Association (ADA) Provider Recognition Program.5 the Guide to Community Preventive Services: Methods, First And in a chart audit covering 1 year in a health Recommendations and Expert Commentary,” pub- maintenance organization (HMO) setting, glycated he- lished in January 2000,11 presents the background and moglobin (GHb)a values were documented for only the methods used to develop the Community Guide. 44% of people with diabetes (ADA recommends two to Evidence reviews and recommendations have been four measurements per year), and annual urine protein published previously on vaccine-preventable diseas- measurements were performed on only 48% of patients.6 es,12–14 tobacco use prevention and control,15–17 and Available evidence shows that improving care for motor vehicle occupant injury.18,19 people with diabetes results in cost savings for health- The Community Guide addresses many of the diabetes- care organizations. In a review of economic analyses of related objectives of Healthy People 2010, the prevention interventions for diabetes, eye care and preconception agenda for the United States.20 Objectives 5-11 through care were found to be cost saving, and preventing 5-15 relate to improving screening for complications neuropathy in type 1b diabetes and improving glycemic involving the kidney, retina, extremities, and the oral control with either type 1 or type 2 diabetes were found cavity and monitoring of glycemic control.20 By imple- to be clearly cost-effective.7 Gilmer et al.8 modeled cost menting interventions shown to be effective, healthcare savings at an HMO and found that every percentage providers and administrators can help their organiza- point increase in hemoglobin A1c (HbA1c) above tions achieve these goals while using resources effi- normal was associated with a significant increase in ciently. This report, in combination with the accompa- costs over the next 3 years. Testa et al.9 noted that nying recommendations,21 provides information on improved glycemic control was associated with short- interventions that can help communities and health- term decreases in healthcare utilization, increased pro- care systems reach Healthy People 2010 objectives. ductivity, and enhanced quality of life. Wagner et al.10 found that a sustained reduction in HbA1c was associ- ated with cost savings among adults with diabetes within Methods 1 to 2 years of improved glycemic control. The Community Guide’s methods for conducting systematic In the last decade, innovative interventions for reviews and linking evidence to effectiveness are described healthcare delivery have emerged that show promise elsewhere.22,23 In brief, for each Community Guide topic, a for improving care, outcomes, and costs for individuals systematic review development team representing diverse and populations with diabetes. Disease and case man- disciplines, backgrounds, and work settings conducts a review by agement are two such new interventions. This review examines the extent and quality of the evidence of their ● developing an approach to identifying, organizing, group- effectiveness when applied to people with diabetes. ing, and selecting interventions for review; ● developing an analytic framework depicting interrelation- ships between interventions, populations, and outcomes; aGHb (including hemoglobin A1c [HbA1c]) describes a series of ● systematically searching for and retrieving evidence; hemoglobin components formed from hemoglobin and glucose, and ● assessing and summarizing the quality and strength of the the blood level reflects glucose
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