KDELR3 polyclonal antibody Gene Summary: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is Catalog Number: PAB26985 achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi Regulatory Status: For research use only (RUO) compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu Product Description: Rabbit polyclonal antibody raised (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. against synthetic peptide of KDELR3. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing Immunogen: A synthetic peptide corresponding to protein, and returns it to the ER. In yeast, the sorting human KDELR3. receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several Host: Rabbit human homologs of the ERD2 gene, constituting the Theoretical MW (kDa): 28 KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be Reactivity: Human,Mouse identified, and it encodes a protein highly homologous to KDELR1 and KDELR2 proteins. Two transcript variants Applications: IHC-P, WB-Ce of KDELR3 that arise by alternative splicing, and encode (See our web site product page for detailed applications different isoforms of KDELR3 receptor, have been information) described. [provided by RefSeq]

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Specificity: KDELR3 polyclonal antibody detects endogenous levels of KDELR3 protein.

Form: Liquid

Purification: Antigen affinity purification

Concentration: 1 mg/mL

Recommend Usage: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.

Storage Buffer: In PBS, pH 7.2 (0.05% sodium azide)

Storage Instruction: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.

Entrez GeneID: 11015

Gene Symbol: KDELR3

Gene Alias: ERD2L3

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