Approach to Shortness of Breath
Total Page:16
File Type:pdf, Size:1020Kb

Load more
Recommended publications
-
Differentiating Between Anxiety, Syncope & Anaphylaxis
Differentiating between anxiety, syncope & anaphylaxis Dr. Réka Gustafson Medical Health Officer Vancouver Coastal Health Introduction Anaphylaxis is a rare but much feared side-effect of vaccination. Most vaccine providers will never see a case of true anaphylaxis due to vaccination, but need to be prepared to diagnose and respond to this medical emergency. Since anaphylaxis is so rare, most of us rely on guidelines to assist us in assessment and response. Due to the highly variable presentation, and absence of clinical trials, guidelines are by necessity often vague and very conservative. Guidelines are no substitute for good clinical judgment. Anaphylaxis Guidelines • “Anaphylaxis is a potentially life-threatening IgE mediated allergic reaction” – How many people die or have died from anaphylaxis after immunization? Can we predict who is likely to die from anaphylaxis? • “Anaphylaxis is one of the rarer events reported in the post-marketing surveillance” – How rare? Will I or my colleagues ever see a case? • “Changes develop over several minutes” – What is “several”? 1, 2, 10, 20 minutes? • “Even when there are mild symptoms initially, there is a potential for progression to a severe and even irreversible outcome” – Do I park my clinical judgment at the door? What do I look for in my clinical assessment? • “Fatalities during anaphylaxis usually result from delayed administration of epinephrine and from severe cardiac and respiratory complications. “ – What is delayed? How much time do I have? What is anaphylaxis? •an acute, potentially -
(Loxapine) REMS
Current as of 6/1/2013.® This document may not be part of the latest approved REMS. Alexza Pharmaceuticals, Inc. 2091 Stierlin Court, Mountain View, CA 94043 IMPORTANT DRUG WARNING Risk of bronchospasm with ADASUVE™ (loxapine) inhalation powder ADASUVE™ available only in enrolled healthcare facilities, under an FDA-required REMS Program Dear Healthcare Professional: This letter contains important safety information for ADASUVE™ (loxapine) Inhalation Powder. ADASUVE is a drug-device combination product that delivers the antipsychotic, loxapine, by oral inhalation. ADASUVE has been approved by the US Food and Drug Administration (FDA) for the acute treatment of agitation associated with schizophrenia or bipolar I disorder in adults. FDA has determined that a Risk Evaluation and Mitigation Strategy (REMS) is necessary to ensure that the benefits of treatment outweigh the risk of bronchospasm in patients treated with ADASUVE. ADASUVE is not available in an outpatient setting. If you are an outpatient provider, you are receiving this letter because ADASUVE may be, or may have been, administered to one of your patients in an enrolled healthcare facility. Enrolled healthcare facilities, such as an acute care or inpatient setting, must have immediate on-site access to equipment and personnel trained to manage acute bronchospasm, including advanced airway management, eg, intubation and mechanical ventilation. (See below for more facility enrollment requirements.) It is important that anyone caring for patients treated with ADASUVE be aware of the risk of bronchospasm after administration. This letter does not contain a complete list of all the risks associated with ADASUVE. Reference ID:Please 3235446 see the enclosed full prescribing information for more information. -
Slipping Rib Syndrome
Slipping Rib Syndrome Jackie Dozier, BS Edited by Lisa E McMahon, MD FACS FAAP David M Notrica, MD FACS FAAP Case Presentation AA is a 12 year old female who presented with a 7 month history of right-sided chest/rib pain. She states that the pain was not preceded by trauma and she had never experienced pain like this before. She has been seen in the past by her pediatrician, chiropractor, and sports medicine physician for her pain. In May 2012, she was seen in the ER after having manipulations done on her ribs by a sports medicine physician. Pain at that time was constant throughout the day and kept her from sleeping. However, it was relieved with hydrocodone/acetaminophen in the ER. Case Presentation Over the following months, the pain became progressively worse and then constant. She also developed shortness of breath. She is a swimmer and says she has had difficulty practicing due to the pain and SOB. AA was seen by a pediatric surgeon and scheduled for an interventional pain management service consult for a test injection. Following good temporary relief by local injection, she was scheduled costal cartilage removal to treat her pain. What is Slipping Rib Syndrome? •Slipping Rib Syndrome (SRS) is caused by hypermobility of the anterior ends of the false rib costal cartilages, which leads to slipping of the affected rib under the superior adjacent rib. •SRS an lead to irritation of the intercostal nerve or strain of the muscles surrounding the rib. •SRS is often misdiagnosed and can lead to months or years of unresolved abdominal and/or thoracic pain. -
Signs and Symptoms of COPD
American Thoracic Society PATIENT EDUCATION | INFORMATION SERIES Signs and Symptoms of COPD Chronic obstructive pulmonary disease (COPD) can cause shortness of breath, tiredness, Short ness of Breath production of mucus, and cough. Many people with COPD develop most if not all, of these signs Avo iding Activities and symptoms. Sho rtness wit of Breath h Man s Why is shortness of breath a symptom of COPD? y Activitie Shortness of breath (or breathlessness) is a common Avoiding symptom of COPD because the obstruction in the A breathing tubes makes it difficult to move air in and ny Activity out of your lungs. This produces a feeling of difficulty breathing (See ATS Patient Information Series fact sheet Shor f B tness o on Breathlessness). Unfortunately, people try to avoid this reath Sitting feeling by becoming less and less active. This plan may or Standing work at first, but in time it leads to a downward spiral of: avoiding activities which leads to getting out of shape or becoming deconditioned, and this can result in even more Is tiredness a symptom of COPD? shortness of breath with activity (see diagram). Tiredness (or fatigue) is a common symptom in COPD. What can I do to treat shortness of breath? Tiredness may discourage you from keeping active, which leads to greater loss of energy, which then leads to more If your shortness of breath is from COPD, you can do several tiredness. When this cycle begins it is sometimes hard to things to control it: break. CLIP AND COPY AND CLIP ■■ Take your medications regularly. -
Inhaled Loxapine Monograph
Inhaled Loxapine Monograph Inhaled Loxapine (ADASUVE) National Drug Monograph February 2015 VA Pharmacy Benefits Management Services, Medical Advisory Panel, and VISN Pharmacist Executives The purpose of VA PBM Services drug monographs is to provide a comprehensive drug review for making formulary decisions. Updates will be made when new clinical data warrant additional formulary discussion. Documents will be placed in the Archive section when the information is deemed to be no longer current. FDA Approval Information Description/Mechanism of Inhaled loxapine is a typical antipsychotic used in the treatment of acute Action agitation associated with schizophrenia and bipolar I disorder in adults. Loxapine’s mechanism of action for reducing agitation in schizophrenia and bipolar I disorder is unknown. Its effects are thought to be mediated through blocking postsynaptic dopamine D2 receptors as well as some activity at the serotonin 5-HT2A receptors. Indication(s) Under Review in Inhaled loxapine is a typical antipsychotic indicated for the acute treatment of this document (may include agitation associated with schizophrenia or bipolar I disorder in adults. off label) Off-label use Agitation related to any other cause not due to schizophrenia and bipolar I disorder. Dosage Form(s) Under 10mg oral inhalation using a new STACCATO inhaler device. Review REMS REMS No REMS Post-marketing Study Required See Other Considerations for additional REMS information Pregnancy Rating C Executive Summary Efficacy Inhaled loxapine was superior to placebo in reducing acute agitation at 2 hours post dose measured by the Positive and Negative Syndrome Scale-Excited Component (PEC) in patients with bipolar I disorder and schizophrenia. -
Hypercapnia in Hemodialysis (HD)
ISSN: 2692-532X DOI: 10.33552/AUN.2020.01.000508 Annals of Urology & Nephrology Mini Review Copyright © All rights are reserved by David Tovbin Hypercapnia in Hemodialysis (HD) David Tovbin* Department of Nephrology, Emek Medical Center, Israel *Corresponding author: David Tovbin, Department of Nephrology, Emek Medical Received Date: February 04, 2019 Center, Afula, Israel. Published Date: February 14, 2019 Introduction 2 case reports and in our experience with similar patients, BiPAP Acute intra-dialytic exacerbation of hypercapnia in hemodialysis prevented intra-dialytic exacerbation of hypercapnia and possibly (HD) patient has been initially reported 18 years ago [1]. Subsequent respiratory arrest [1,2]. In recent years, new interest was raised similar case was reported few years later [2]. Common features of to HD dialysate bicarbonate concentration. After standardizing to both patients were morbid obesity, a previously stable HD sessions and an acute respiratory infection at time of hypercapnia [1,2]. HD pre-dialysis serum bicarbonate level was recommended as >22 patients with decreased ventilation reserve, due to morbid obesity inflammation malnutrition complex and comorbidities midweek mEq/L [11]. As higher dialysate bicarbonate concentration became with or without obstructive sleep apnea (OSA) and/or obesity more prevalent, a large observation cohort study demonstrated hypoventilation syndrome (OHS) as well as chronic obstructive that high dialysate bicarbonate concentration was associated pulmonary disease (COPD), are at increased risk. COPD is common with worse outcome especially in the more acidotic patients among HD patients but frequently under-diagnosed [3]. Most [12]. However, still not enough attention is paid to HD dialysate COPD patients do well during HD with only mild- moderate pCO2 bicarbonate in the increasing number of patients with impaired increases and slightly decreased pH as compared to non-COPD ventilation, and to their risk of intra-dialytic exacerbation of chronic HD patients [2,4]. -
Basic Life Support Health Care Provider
ELLIS & ASSOCIATES Health Care Provider Basic Life Support MEETS CURRENT CPR & ECC GUIDELINES Ellis & Associates / Safety & Health HEALTH CARE PROVIDER BASIC LIFE SUPPORT - I Ellis & Associates, Inc. P.O. Box 2160, Windermere, FL 34786-2160 www.jellis.com Copyright © 2016 by Ellis & Associates, LLC All rights reserved. No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the publisher, except in the case of brief quotations embodied in critical reviews and certain other noncommercial uses permitted by copyright law. For permission requests, write to the publisher, addressed “Attention: Permissions Coordinator,” at the address below. Ellis & Associates P.O. Box 2160, Windermere, FL 34786-2160 Ordering Information: Quantity sales. Special discounts are available on quantity purchases by corporations, associations, trade bookstores and wholesalers. For details, contact the publisher at the address above. Disclaimer: The procedures and protocols presented in this manual and the course are based on the most current recommendations of responsible medical sources, including the International Liaison Committee on Resuscitation (ILCOR) 2015 Guidelines for CPR & ECC. Ellis & Associates, however, make no guarantee as to, and assume no responsibility for, the correctness, sufficiency, or completeness of such recommendations or information. Additional procedures may be required under particular circumstances. Ellis & Associates disclaims all liability for damages of any kind arising from the use of, reference to, reliance on, or performance based on such information. Library of Congress Cataloging-in-Publication Data Not Available at Time of Printing ISBN 978-0-9961108-0-8 Unless otherwise indicated on the Credits Page, all photographs and illustrations are copyright protected by Ellis & Associates. -
Appendix A: Codes Used to Define Principal Diagnosis of COVID-19, Sepsis, Or Respiratory Disease
Appendix A: Codes used to define principal diagnosis of COVID-19, sepsis, or respiratory disease ICD-10 code Description N J21.9 'Acute bronchiolitis, unspecified' 1 J80 'Acute respiratory distress syndrome' 2 J96.01 'Acute respiratory failure with hypoxia' 15 J06.9 'Acute upper respiratory infection, unspecified' 7 U07.1 'COVID-19' 1998 J44.1 'Chronic obstructive pulmonary disease with (acute) exacerbation' 1 R05 'Cough' 1 O99.52 'Diseases of the respiratory system complicating childbirth' 3 O99.512 'Diseases of the respiratory system complicating pregnancy, second trimester' 1 J45.41 'Moderate persistent asthma with (acute) exacerbation' 2 B97.29 'Other coronavirus as the cause of diseases classified elsewhere' 33 J98.8 'Other specified respiratory disorders' 16 A41.89 'Other specified sepsis' 1547 J12.89 'Other viral pneumonia' 222 J12.81 'Pneumonia due to SARS-associated coronavirus' 2 J18.9 'Pneumonia, unspecified organism' 8 R09.2 'Respiratory arrest' 1 J96.91 'Respiratory failure, unspecified with hypoxia' 1 A41.9 'Sepsis, unspecified organism' 155 R06.02 'Shortness of breath' 1 J22 'Unspecified acute lower respiratory infection' 4 J12.9 'Viral pneumonia, unspecified' 6 Appendix B: Average marginal effect by month, main analysis and sensitivity analyses Appendix C: Unadjusted mortality rate over time, by age group Appendix D: Results restricted to COVID-19, sepsis, or respiratory disease Any chronic Adjusted mortality Standardized Average marginal Age, median Male, Mortality, Month N condition, (95% Poisson limits) mortality ratio -
Beta Adrenergic Agents
Beta2 Adrenergic Agents –Long Acting Review 04/10/2008 Copyright © 2007 - 2008 by Provider Synergies, L.L.C. All rights reserved. Printed in the United States of America. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, digital scanning, or via any information storage and retrieval system without the express written consent of Provider Synergies, L.L.C. All requests for permission should be mailed to: Attention: Copyright Administrator Intellectual Property Department Provider Synergies, L.L.C. 5181 Natorp Blvd., Suite 205 Mason, Ohio 45040 The materials contained herein represent the opinions of the collective authors and editors and should not be construed to be the official representation of any professional organization or group, any state Pharmacy and Therapeutics committee, any state Medicaid Agency, or any other clinical committee. This material is not intended to be relied upon as medical advice for specific medical cases and nothing contained herein should be relied upon by any patient, medical professional or layperson seeking information about a specific course of treatment for a specific medical condition. All readers of this material are responsible for independently obtaining medical advice and guidance from their own physician and/or other medical professional in regard to the best course of treatment for their specific medical condition. This publication, inclusive of all forms contained herein, is intended to be educational in nature and is intended to be used for informational purposes only. Comments and suggestions may be sent to [email protected]. -
Breathing Better with a COPD Diagnosis
Difficulty Breathing Chronic Bronchitis Smoker’s Cough Chronic Coughing Wheezing Em- Chronic Obstructive Pulmonary Disease physema Shortness of Breath Feeling of Suffocation Excess Mucus Difficulty Breathing Chronic Bronchitis Smoker’s Cough Chronic Coughing Wheezing Emphysema Shor tness of Breath Feeling of Suffocation Excess Mucus Difficulty Breathing Chronic Bronchitis Smoker’s Cough Chronic Coughing Wheezing Emphysema Shortness of Breath Feeling of Suffocation Excess Mucus Difficulty Breathing Chronic Bronchitis Smoker’s Cough Chron- ic Coughing Wheezing Emphysema Shortness of Breath Feeling of Suffocation Excess Mu- cus DifficultyBreathing Breathing Chronic Bronchitis Better Smoker’s Cough Chronic Coughing Wheezing Emphysema Shortness of Breath Feeling of Suffocation Excess Mucus Difficulty Breathing Chronic Bronchitis Smoker’s Cough Chronic Coughing Wheezing Emphysema Shor tness of Breath Feeling of SuffocationWith Excess a COPDMucus Difficulty Diagnosis Breathing Chronic Bronchitis Smoker’s Cough Chronic Coughing Wheezing Emphysema Shortness of Breath Feeling of did you know? When COPD is severe, shortness of breath and other COPDdid you is the know? 4th leading cause of death in the symptomswhen you can get are in the diagnosed way of doing even the most UnitedCOPD States.is the 4th The leading disease cause kills ofmore death than in 120,000 basicwith tasks, copd such as doing light housework, taking a Americansthe United eachStates year—that’s and causes 1 serious, death every long-term 4 walk,There and are even many bathing things and that getting you can dressed. do to make minutes—anddisability. The causesnumber serious, of people long-term with COPDdisability. is COPDliving withdevelops COPD slowly, easier: and can worsen over time, increasing.The number More of people than 12with million COPD people is increasing. -
Rivaroxaban (Xarelto®)
Rivaroxaban (Xarelto®) To reduce your bleeding and clotting risk it is important that you attend follow-up appointments with your provider, and have blood tests done as your provider orders. What is rivaroxaban (Xarelto®)? • Rivaroxaban is also called Xarelto® • Rivaroxaban(Xarelto®) is used to reduce the risk of blood clots and stroke in people with an abnormal heart rhythm known as atrial fibrillation, in people who have had a blood clot, or in people who have undergone orthopedic surgery. o Blood clots can block a blood vessel cutting off blood supply to the area. o Rarely, clots can break into pieces and travel in the blood stream, lodging in the heart (causing a heart attack), the lungs (causing a pulmonary embolus), or in the brain (causing a stroke). • If you were previously on Warfarin/Coumadin® and you are starting Rivaroxaban(Xarelto®), do not continue taking warfarin. Rivaroxaban(Xarelto®) replaces warfarin. Xarelto 10mg tablet Xarelto 15mg tablet Xarelto 20mg tablet How should I take rivaroxaban (Xarelto®)? • Take Rivaroxaban(Xarelto®) exactly as prescribed by your doctor. • Rivaroxaban(Xarelto®) should be taken with food. • Rivaroxaban(Xarelto®) tablets may be crushed and mixed with applesauce to make the tablet easier to swallow. - 1 - • If you missed a dose: o Take it as soon as you remember on the same day. • Do not stop taking rivaroxaban suddenly without telling your doctor. This can put you at risk of having a stroke or a blood clot. • If you take too much rivaroxaban, call your doctor or the anticoagulation service. If you are experiencing any bleeding which you cannot get to stop, go to the nearest emergency room. -
AC01 Page 1 of 2 Effective Jan
Contra Costa County Emergency Medical Services Cardiac Arrest History Signs and Symptoms Differential • Code status (DNR or POLST) • Unresponsive • Medical vs. trauma • Events leading to arrest • Apneic • VF vs. pulseless VT • Estimated downtime • Pulseless • Asystole • History of current illness • PEA • Past medical history • Primary cardiac event vs. respiratory arrest or drug • Medications overdose • Existence of terminal illness Decomposition AT ANY TIME Rigor mortis Criteria for death/no resuscitation Dependent lividity Yes Review DNR/POLST form Return of spontaneous circulation Injury incompatible with life or traumatic arrest with No asystole Follow FP09 ‐ Cardiac Arrest Go to Post Resuscitation TG Do not begin resuscitation Management Follow Policy 1004 – Determination of Death Begin continuous chest compressions Push hard (> 2 inches) and fast (100‐120/min) For suspected Excited Use metronome to ensure proper rate Delirium patients E Change compressors every 2 minutes (Limit changes/pulse checks to < 5 seconds) Consider fluid bolus early and Apply mechanical compression device contact Base Hospital for if available Sodium Bicarbonate order No ALS available? Yes E Apply AED if available Cardiac monitor P EtCO2 monitoring Shockable rhythm? Yes No Shockable rhythm? No Yes Continue CPR Automated defibrillation E 5 cycles over 2 minutes Follow Follow VF/VT Repeat and assess Asystole/PEA E Continue CPR and Airway TG and Airway TG 5 cycles over 2 minutes as indicated Repeat and assess as indicated Follow Airway TG Follow Airway TG Notify receiving facility. Contact Base Hospital for medical direction, as needed. Treatment Guideline AC01 Page 1 of 2 Effective Jan. 2016Effective Jan. 2020 Contra Costa County Emergency Medical Services Cardiac Arrest Pearls • Efforts should be directed at high quality and continuous chest compressions with limited interruptions.