Recommendations for Governance and Policies in the COVID-19 Response
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Viruses in Food: Scientific Advice to Support Risk Management Activities
For further information on the joint FAO/WHO activities on microbiological risk assessment, please contact: Nutrition and Consumer Protection Division Food and Agriculture Organization of the United Nations Viale delle Terme di Caracalla 00153 Rome, Italy Fax: +39 06 57054593 E-mail: [email protected] Web site: http://www.fao.org/ag/agn/agns or Department of Food Safety, Zoonoses and Foodborne Diseases World Health Organization 20 Avenue Appia CH-1211 Geneva 27 Switzerland Fax: +41 22 7914807 E-mail: [email protected] Web site: http//www.who.int/foodsafety Cover design: Food and Agriculture Organization of the United Nations and the World Health Organization Cover picture: © Dennis Kunkel Microscopy, Inc. MICROBIOLOGICAL RISK ASSESSMENT SERIES 13 Viruses in food: scientific advice to support risk management activities MEETING REPORT WORLD HEALTH ORGANIZATION FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS 2008 5IFEFTJHOBUJPOTFNQMPZFEBOEUIFQSFTFOUBUJPOPGNBUFSJBMJOUIJTJOGPSNBUJPO QSPEVDUEPOPUJNQMZUIFFYQSFTTJPOPGBOZPQJOJPOXIBUTPFWFSPOUIFQBSUPGUIF 'PPEBOE"HSJDVMUVSF0SHBOJ[BUJPOPGUIF6OJUFE/BUJPOT '"0 PSPGUIF8PSME )FBMUI0SHBOJ[BUJPO 8)0 DPODFSOJOHUIFMFHBMPSEFWFMPQNFOUTUBUVTPGBOZ DPVOUSZ UFSSJUPSZ DJUZPSBSFBPSPGJUTBVUIPSJUJFT PSDPODFSOJOHUIFEFMJNJUBUJPOPGJUT GSPOUJFSTPSCPVOEBSJFT5IFWJFXTFYQSFTTFEIFSFJOBSFUIPTFPGUIFBVUIPSTBOEEPOPU OFDFTTBSJMZSFQSFTFOUUIPTFPG'"0OPSPG8)0OPSPGUIFJSBGGJMJBUFEPSHBOJ[BUJPO T "MMSFBTPOBCMFQSFDBVUJPOTIBWFCFFOUBLFOCZ'"0BOE8)0UPWFSJGZUIFJOGPSNBUJPO DPOUBJOFEJOUIJTQVCMJDBUJPO)PXFWFS UIFQVCMJTIFENBUFSJBMJTCFJOHEJTUSJCVUFE -
Speakers' Biographies 4Th Annual Short Course in Medical Virology Of
Speakers’ Biographies 4th Annual Short Course in Medical Virology of the GVN Clement A. Adebamowo, BM, ChB, ScD, FWACS, FACS. As a member of the Population Sciences Program of the Cancer Center and a cancer epidemiologist, I conduct research on the epidemiology of cancer. At this time, I am the PI of the NIH funded African Collaborative Center for Microbiome and Genomics Research (ACCME) which is one of the NIH/Wellcome Trust funded Human Heredity and Health in Africa (H3Africa) initiative on genomics research and education in Africa. ACCME’s current project is enrolling 10,000 women in Nigeria and Zambia and following them up every 6 months for research focused on integrative epidemiology of persistent high risk HPV infection, host germline and somatic genomics and epigenomics, and vaginal microenvironment (cytokines and microbiome) and risk of cervical cancer. As part of this project, I established a comprehensive genomics laboratory in Nigeria including facilities for epigenetics and next generation sequencing using Illumina NextSeq500. The genomics lab is linked to an NIH funded biorepository at IHVN. I also direct the Fogarty funded West African Bioethics Training program which has provided medium term training leading to Certificates in Research Ethics for 842 biomedical researchers, Masters’ degree in Bioethics to 34 individuals and Online WAB-CITI Training program to 6115 participants in West Africa. In Baltimore, I am working with colleagues at the University of Maryland Greenebaum Cancer Center and University of Maryland College Park to develop a research program on cancer disparities among Africans in Africa, recent African immigrants to the United States and African Americans in order to better understand the role of genetics, environment cultural and socio- economic factors in cancer prevention, treatment seeking behavior and outcomes. -
COVID-19 China Mission VPC 09 Feb 2021
COVID-19 China Mission VPC 09 Feb 2021 Speaker key: MF Mi Feng LW Professor Liang Wannian PE Mr Peter Ben Embarek MK Madam Marion Koopmans QU Questioners 00:00:23 MF Ladies and gentlemen, dear friends, good afternoon. Welcome to the press conference of joint expert team of China WHO SARS-CoV-2 origin research. This is Mi Feng, the spokesperson of China National Health Commission. Since COVID-19 became a global pandemic, WHO has been actively promoting the international cooperation in terms of the COVID-19 response. China has always been showing firm support to WHO in terms of unleashing the role of WHO in the leadership of the global COVID-19 response. 00:01:55 With the consensus based on two-sides negotiation, China and WHO have conducted joint research of the SARS-CoV-2 global source-tracing including the China parts since the arrival of international expert teams in Wuhan from January 14, 2021. The joint expert team has been working from three groups, respectively, the group of epidemiology, molecular research, animal and environment. The experts have been working in the forms of video conferences, onsite interviews and visits, and also discussions. They have conducted systematic and full-fledged research. They have already concluded the China part of the source-tracing in Wuhan according to the original plan. During this period, Mr Ma Xiaowei, the minister of China National Health Commission, has been discussing and having abundant communication with Dr Tedros, the Director-General of WHO, through telephone. They have fully exchanged their ideas in terms of the scientific cooperation in the origin source-tracing. -
COVID-19 Virtual Press Conference 12 February 2021
COVID-19 Virtual Press conference 12 February 2021 Speaker key: FC Fadela Chaib TAG Dr Tedros Adhanom Ghebreyesus RO Robin PBE Dr Peter Ben Embarek PA Paulina TR Translator SS Dr Soumya Swaminathan MK Dr Maria Van Kerkhove HE Helen MR Dr Michael Ryan ME Megan MA Professor Marion Koopmans SI Simone DA David SO Sophie BA Dr Bruce Aylward SH Shoko DO Donato 00:00:48 FC Good afternoon, everyone. This is Fadela Chaib speaking to you from WHO headquarters in Geneva and welcoming you to our global COVID-19 press conference today, Friday 12th February. Simultaneous interpretation is provided in the six official UN languages plus Portuguese and Hindi. Let me introduce to you the participants at this press conference. Present in the room are Director-General of WHO, Dr Tedros, Dr Mike Ryan, Executive Director, Health Emergencies, Dr Maria Van Kerkhove, Technical Lead for COVID-19, Dr Soumya Swaminathan, Chief Scientist, Dr Bruce Aylward, Special Advisor to the Director-General and Lead on the ACT Accelerator. Joining us remotely are Dr Kate O'Brien, Director, Immunisation, Vaccines and Biologicals and Dr Janet Diaz, Team Lead, Healthcare Readiness. We also have present in the room a member of the international team to China, Dr Peter Ben Embarek. He's also an expert at WHO on food safety and zoonosis and team lead of the international team. Joining remotely is Professor Marion Koopmans, Head of the Department of Viroscience at the University of Rotterdam. Now without further delay I would like to hand over to Dr Tedros for his opening remarks. -
NS Annual Report 2020
NS Annual report 2020 See www.nsannualreport.nl for the online version The NS Annual Report 2020 is published in Dutch and English. In the event of discrepancies between the versions, the Dutch version prevails. Table of contents 3 In Brief 4 Foreword by the CEO 7 2020: A year dominated by COVID-19 15 Our strategy 19 Expected developments in the long term 21 How NS adds value to society 25 Our impact on the Netherlands 31 The profile of NS 36 Compensation for victims of WWII transports Our activities and achievements in the Netherlands 38 Our performance on the main rail network and the high-speed line 40 Customer satisfaction with the main rail network and the high-speed line 44 Performance on the main rail network and the high-speed line 49 Door-to-door journey 53 Stations and their environment 59 Travelling and working in safety 63 Performance on sustainability 71 Attractive and inclusive employer Our activities and achievements abroad 78 Abellio 84 Abellio UK 99 Abellio Germany Financial performance 108 Finance in brief NS Group 116 Report of the Supervisory Board 129 Corporate governance 134 Risk management 141 Organisational improvements 145 Dialogue with our stakeholders in the Netherlands 160 Notes to the material themes 162 About the scope of this report 164 Scope and reporting criteria Financial statements 167 Consolidated financial statements 244 Company financial statements Other information 248 Other information 248 Combined independent auditor’s report and assurance report 263 NS ten-year summary 265 Disclaimer 2 | In Brief 3 | Foreword by the CEO Over the past year, NS has proved to be a healthy company that is able to keep the Netherlands moving despite huge setbacks. -
The Scientists Investigating the Pandemic's Origins
News in focus is on the table,” says Koopmans. Another member, Hung Nguyen, an environ- ment and food-safety researcher at the International Livestock Research Institute in Nairobi, will contribute his knowledge on how pathogens spread in wet markets, similar to the Huanan seafood market in Wuhan, which many of the first people reported to have COVID-19 had visited. Nguyen has investigated how salmonella and other bacteria spread through smallholder farms, slaughterhouses and live-animal markets in his home country of Vietnam and across southeast Asia. Also on the team is Peter Daszak, president of the non-profit research organization Ecohealth Alliance in New York City, who has spent more than a decade studying coronaviruses. He has worked closely with the Wuhan Institute of Virology (WIV) to test bats for coronaviruses with the potential to spill over into people. “It is an honour to be part of this team,” says Daszak. “There hasn’t been a pandemic on this scale since the 1918 flu, and we’re still close KONIG/IMAGEBROKER/SHUTTERSTOCK MARKO SARS-CoV-2 probably originated in bats, but how it passed to people is being investigated. enough to the origin to really find out more details about where it has come from.” Another team member, Fabian Leendertz, a veterinary researcher at the Robert Koch THE SCIENTISTS Institute in Berlin, will bring his expertise in spillover events. In April 2014, Leendertz vis- INVESTIGATING THE ited Meliandou village in Guinea, months after a two-year-old died of Ebola — the first person PANDEMIC’S ORIGINS reported to be infected in West Africa. -
NATO Public Opinion on Nuclear Weapons January 2021
NATO Public Opinion on Nuclear Weapons January 2021 Introduction New surveys reveal large segments of the population in six NATO states favor the alliance taking a drastically new course when it comes to nuclear weapons. They overwhelmingly support the Treaty on the Prohibition of Nuclear Weapons (TPNW) and reject the station of nuclear weapons on their soil.Despite NATO’s official opposition to the 2017 TPNW, the new findings track with several recent public opinion polls show that public support stands firmly behind the ban and citizens no longer want their countries to participate in NATO’s nuclear sharing program. The polls, conducted in 2020 in Belgium, Denmark, Iceland, Italy, the Netherlands and Spain, show that support for the TPNW and removing nuclear weapons is growing and that these states should choose to be among the first NATO states to join the treaty. The treaty takes full effect on 22 January 2021 and within one year the countries that have joined the treaty will meet to discuss its full implementation. There is no legal barrier for NATO states to join, on the contrary, there are many advantages for them to do so. Now is the time for NATO states to implement its democratic values and follow public opinion to join the treaty. Key Findings NATO public stand behind the ban Support for NATO countries to join the TPNW remains high with 89% of Spanish, 87% of Italians, 86% of Icelanders, 78% of Dutch and Danish and 77% of Belgians supporting their country joining the treaty. Percentage of respondents who answered “yes” to the question: “Do you think your country should join the UN Treaty on the Prohibition of Nuclear Weapons?” Public support for official state position is extremely low What’s more, actual support for the official government policy to not join the TPNW is often in the single digits. -
Human Monkeypox – Epidemiological and Clinical Characteristics, Diagnosis and Prevention
1 Chapter/Review 12 Clinical Review for IDCNA IDC 33.4 Emerging and Re-Emerging Infectious Diseases Title: Human Monkeypox – Epidemiological and Clinical characteristics, Diagnosis and Prevention Authors*: Eskild Petersen, Anu Kantele, Marion Koopmans, Danny Asogun, Adesola Ogunlete, Chikwe Ihekweazu and Alimuddin Zumla (* All authors contributed equally) Institutional affiliations: Eskild Petersen: Institute of Clinical Medicine, University of Aarhus, Denmark and The Royal Hospital, Muscat, Oman. European Society for Clinical Microbiology and Infectious Diseases Task Force for Emerging Infections, Basel, Switzerland. Email: [email protected] Anu Kantele: Inflammation Center, Helsinki University Hospital and Helsinki University, Helsinki, Finland. Email: [email protected] Marion Koopmans: Viroscience Department, Erasmus Medical Centre, Rotterdam, The Netherlands. Email: [email protected] Danny Asogun: Department of Public Health, Faculty of Clinical Sciences, College of Medicine, Ambrose Alli University, Ekpoma, Nigeria. Email: [email protected] Adesola Ogunleye: Nigeria Centre for Disease Control, Jabi, Abuja, Nigeria. Email: [email protected] Chikwe Ihekweazu: Nigeria Centre for Disease Control, Jabi, Abuja, Nigeria. Email: [email protected] Alimuddin Zumla: Division of Infection and Immunity, Center for Clinical Microbiology, University College London, and the National Institute of Health Research Biomedical Research Centre at UCL Hospitals, London, UK. Email. [email protected] Mailing Addresses: -
Infectious Disease Detection in the Era of Next Generation Sequences: Opportunities, Challenges, and the COMPARE Project
COllaborative Management Platform for detection and Analyses of (Re-) emerging and foodborne outbreaks in Europe Infectious disease detection in the era of next generation sequences: opportunities, challenges, and the COMPARE project Prof. Marion Koopmans, (Erasmus Medical Center, the Netherlands) @MarionKoopmans Prof Frank Aarestrup (DTU, Denmark) This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement 643476 Enterovirus 68 MERS CoV Avian influenza H7N9 China H5N1 Egypt Infectious disease situation 2015 • Dynamics of common infectious diseases are changing – Demographic change, population density, anti vaccine movement, AMR, etc. • New diseases emerge frequently – Deforestation, population growth, health systems inequalities, travel, trade, climate change • Effects are difficult to predict due to complexity of problems • Public health and clinical response depend on global capacity for disease surveillance Start outbreak EBOV • March 10, 2014 notification unknown disease characterized by fever, severe diarrhea, vomiting and high fatality rate in Guéckédou and Macenta in Guinea. • March 22, EVD reported by Guinea to WHO. • March 27, EVD suspected cases in Liberia and Sierra Leone related to outbreak in Guinea. • April 3d: ZEBOV Dx * Diagnosis < 2 yr old seeding through funeral > < seeding through HCW Animal surveillance, Gabon 2001-3 Fruit bats Duikers Primates Outbreaks in animals detected prior to (4/5) human disease outbreaks Convincing evidence for bushmeat related -
Avian Influenza a Virus (H7N7) Associated with Human Conjunctivitis and a Fatal Case of Acute Respiratory Distress Syndrome
Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome Ron A. M. Fouchier†‡, Peter M. Schneeberger§, Frans W. Rozendaal§, Jan M. Broekman§, Stiena A. G. Kemink§, Vincent Munster†, Thijs Kuiken†, Guus F. Rimmelzwaan†, Martin Schutten†, Gerard J. J. van Doornum†, Guus Koch¶, Arnold Bosmanʈ, Marion Koopmansʈ, and Albert D. M. E. Osterhaus† †Department of Virology and National Influenza Center, Erasmus Medical Center, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands; §Jeroen Bosch Hospital, Nieuwstraat 34, 5211 NL, Den Bosch, The Netherlands; ¶Section of Notifiable and Exotic Viral Diseases, Central Institute for Animal Disease Control, P.O. Box 147, 8200 AC, Lelystad, The Netherlands; and ʈCenter for Infectious Disease Epidemiology and Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute of Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, 3720 BA, Bilthoven, The Netherlands Communicated by Peter Palese, Mount Sinai School of Medicine, New York, NY, December 16, 2003 (received for review November 28, 2003) Highly pathogenic avian influenza A viruses of subtypes H5 and H7 (1, 2). Because of the recent increase in awareness of AIV are the causative agents of fowl plague in poultry. Influenza A zoonoses and the increase in the intensity of surveillance studies, viruses of subtype H5N1 also caused severe respiratory disease in sporadic zoonotic infections with H9N2 AIV in China have been humans in Hong Kong in 1997 and 2003, including at least seven detected also (16). The transmission of AIV from birds to fatal cases, posing a serious human pandemic threat. Between the humans, therefore, continues to be a threat to public health. -
WHO- AUDIO Emergencies C Oronavirus Press Conf Erence COVID19 Origi Ns Mission 30MAR20 21 (1) Virtual Press Conference 30 March 2021
WHO- AUDIO_Emergencies_C oronavirus_Press_Conf erence_COVID19_Origi ns_Mission_30MAR20 21 (1) Virtual Press conference 30 March 2021 Speaker key: TJ Tarik Jasarevic PBE Dr Peter Ben Embarek TF Professor Dr Thea Fisher JW Professor John Watson MK Professor Dr Marion Koopmans DD Professor Dr Dominic Dwyer VD Vladimir Dedkov HNV Dr Hung Nguyen-Viet FL PD. Dr. med vet. Fabian Leendertz PD Dr Peter Daszak FAL Dr Farag El Moubasher KM Professor Dr Ken Maeda IS Isabel Sacco JL Jérémie Lanche DY Du Yang SN Sarah Newey KS Kier Simmons SH Shoko Koyama KV Karen Weintraub JZ John Zarocostas AN Anjalee Khemlani CO Christiane Oelrich RM Robin Millard SJ Sara Jerving 00:00:03 TJ Hello, good evening, good afternoon or good morning to everyone. My name is Tarik Jasarevic, and I’m welcoming you to our press conference regarding the publication of the report that was looking into origin of SARS- COV2 virus. The report itself has just been published on our website. We have sent the link to the webpage where the report is placed, as well as the press release and opening remarks by Dr Tedros at today’s meeting with member states where the report was presented. The report, as I said, describes the findings of the Wuhan field visit that took place from January 14th to February 10th, and that was conducted by a group of international scientists and Chinese scientists, as mandated by the World Health Assembly Resolution that was adopted in May last year. So, here today, we are to present those findings to the members of the media. -
VEO Kick-Off Meeting Report 04-05 June 2020
Versatile Emerging infectious disease Observatory Forecasting, nowcasting and tracking in a changing world VEO Kick-off Meeting Report 04-05 June 2020 1 Versatile Emerging infectious disease Observatory Forecasting, nowcasting and tracking in a changing world Contents 04 June 2020, The VEO Project and COVID-19 ............................................................................................. 3 Evelyn Depoortere, EC Scientific Officer ................................................................................................... 3 Marion Koopmans, EMC, VEO – the project ............................................................................................. 3 VEO & COVID: Unravelling the infodemic ..................................................................................................... 5 Marcel Salathé, EPFL, Digital epi and COVID ............................................................................................ 5 Daniel Remondini, UNIBO, Network Analysis of social media data .......................................................... 6 VEO & COVID: Forecasting, nowcasting and tracking ................................................................................... 7 Luisa Barzon, UNIPD, The COVID epidemic in northern Italy ................................................................... 7 Simon Cauchemez, IP, Estimating epidemic size and trajectories: the challenges .................................. 8 Bas Oude Munnink, EMC, Precision public health, real-time sequencing to track and support