Anti-UCP3 (aa 100-200) polyclonal antibody (DPABH-15879) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description UCP are mitochondrial transporter that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.

Immunogen Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human UCP3.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, ICC/IF

Format Liquid

Size 100 μg

Buffer Constituents: 1% BSA, PBS, pH 7.4

Preservative 0.02% Sodium Azide

Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

Gene Name UCP3 uncoupling 3 (mitochondrial, proton carrier) [ Homo sapiens ]

Official Symbol UCP3

Synonyms UCP3; 3 (mitochondrial, proton carrier); mitochondrial uncoupling protein 3; SLC25A9; UCP 3; Uncoupling protein-3; 25 member 9;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene ID 7352

Protein Refseq NP_003347

UniProt ID P55916

Chromosome Location 11q13.4

Pathway Diurnally regulated with circadian orthologs; Electron Transport Chain; Energy Metabolism; Metabolism; Mitochondrial Uncoupling Proteins; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling prote

Function oxidative phosphorylation uncoupler activity; transporter activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved