Anti-SH2B3 monoclonal antibody, clone 3E9 (DCABH-1385) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to LNK

Antigen Description Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase.

Immunogen Recombinant full length Human LNK produced in HEK293T cells (NP_005466).

Isotype IgG1

Source/Host Mouse

Species Reactivity Human

Clone 3E9

Purity Protein G purified

Purification Purified from Mouse ascites fluid by affinity chromatography.

Conjugate Unconjugated

Applications WB, Flow Cyt, ICC/IF

Positive Control HEK293T cells transfected with pCMV6-ENTRY LNK and lysate thereof; COS7 cells transiently transfected with pCMV6-ENTRY LNK; HeLa cells.

Format Liquid

Size 100 μl

Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 48% PBS, 50% Glycerol, 1% BSA

Preservative 0.02% Sodium Azide

Storage store at -20°C. Avoid repeated freeze / thaw cycles.

Ship Shipped at 4°C.

GENE INFORMATION

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Name SH2B3 SH2B adaptor protein 3 [ Homo sapiens ]

Official Symbol SH2B3

Synonyms SH2B3; SH2B adaptor protein 3; SH2B adapter protein 3; IDDM20; LNK; lymphocyte adaptor protein; signal transduction protein Lnk; lymphocyte-specific adapter protein Lnk;

Entrez Gene ID 10019

Protein Refseq NP_005466

UniProt ID B7Z7K6

Chromosome Location 12q24.12

Pathway EPO signaling pathway, organism-specific biosystem; Factors involved in megakaryocyte development and production, organism-specific biosystem; Hemostasis, organism- specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; Regulation of KIT signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem;

Function signal transducer activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved