SunLong Biotech Co.,LTD Tel: 0086-571- 56623320 Fax:0086-571- 56623318 E-mail:[email protected] www.sunlongbiotech.com

Rabbit Anti-IFNA14/FITC Conjugated antibody

SL15519R-FITC

Product Name: Anti-IFNA14/FITC Chinese Name: FITC标记的Interferonalpha 14蛋白抗体 IFN-alpha-14; IFN14_HUMAN; IFNA14; alpha 14; Interferon alpha H; Alias: Interferon alpha-14; Interferon alpha-H; Interferon lambda-2-H; Interferon lambda2H; LeIF H; LeIFH; MGC125756; MGC125757. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 20kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human IFNA14 Lsotype: IgG Purification: affinity purified by A Storage Buffer: 0.01Mwww.sunlongbiotech.com TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: The encoding type I (IFNs), which include 14 IFN-alpha genes, 1 IFN-beta , 1 IFN-omega (also known as IFN-alpha II1) gene, and a number of IFN-omega pseudogenes, are clustered on human 9. Interferon-alpha and - Product Detail: beta are that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-omega is antigenically different from human IFN-alpha, IFN-beta or IFN-gamma, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-alpha R) interacts with IFN-alpha, IFN-beta and IFN- omega, and seems to be a multisubunit receptor.

Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Subcellular Location: Secreted.

Similarity: Belongs to the alpha/beta interferon family.

Database links:

Entrez Gene: 3448 Human

Omim: 147579 Human

SwissProt: P01570 Human

Unigene: 93907 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. www.sunlongbiotech.com