Product datasheet Anti-ITGB1 Antibody Catalog Number: BM4308

BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Basic Information Product Name Anti-ITGB1 Antibody Name ITGB1 Source Rabbit Species Reactivity human,mouse,rat Tested Application WB,IHC-P Contents 500ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Immunogen A synthesized peptide derived from human beta 1 Purification Affinity-chromatography Observed MW 140KD Dilution Ratios Western blot: 1:500-2000 Immunohistochemistry in paraffin section: 1:20-100

Storage 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing

Background Information Integrin beta-1, also known as CD29, is a that in humans is encoded by the ITGB1 gene. CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create alpha3beta1 complex that reacts to such molecules as netrin-1 and . This gene contains a beta subunit that appears to be analogous to band-3 of integrin. It is mapped to 10p11.22. It is found that FER mediates crosstalk between CDH2 and CD29. Integrin family members are membrane receptors involved in and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit.

Reference

Anti-ITGB1 Antibody被引用在1文献中。

Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: PubMed:26498639 Anin vitroinvestigation | Cheng XD, Gu JF, Yuan JR, Feng L, Jia XB | Mol Med Rep. 2015 Dec; 12(6): 7992–8002.Published online 2015 Oct 15.doi:10.3892/mmr.2015.4449

FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 1 Product datasheet Anti-ITGB1 Antibody Catalog Number: BM4308

BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Selected Validation Data

Western blot analysis of Immunohistochemical analysis of paraffin- expression in A431 cell embedded human breast lysate. cancer, using Integrin beta 1 Antibody.

FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 2

Powered by TCPDF (www.tcpdf.org)