SERVIER - RESEARCH INSTITUTE

ACCELERATING RESEARCH TODAY TO REACH A HEALTHIER TOMORROW THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE

44,500 m² building

4,800 m² green space

Architects: Wilmotte & Associés

Working space for 800 employees

A 1,850 m² start-up incubator with up to 80 workstations

DUE TO OPEN IN 2022

2 THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE FOREWORD

“THE NEW FACE OF SERVIER R&D IN PARIS-SACLAY”

Research is the cornerstone of Servier’s vocation, committed in and Europe and will to therapeutic progress to serve be the only international pharma patient needs. The Servier Paris- present in this unique cluster. Saclay Research Institute will Servier’s researchers will be drive our ambition to provide able to interact with a vibrant Christophe THURIEAU patients with breakthrough scientific and medical ecosystem, Executive Director, therapeutic innovations. gaining access to complementary Servier Research Institute expertise to accelerate Innovating as a network, innovation. without barriers, is critical to responding even more effectively Locating our Research Institute and quickly to patients’ unmet in Paris-Saclay bolsters our needs. At Paris-Saclay, the ambition to accelerate research Group affirms its position among today so as to reinvent healthcare the most powerful innovators tomorrow.

About Servier

100 million patients An independent Servier medicines treated each day with 22,000 prescibed in group governed by a employees Servier medicines non-profit Foundation 149 countries

3 Research 15 International 16 production 25% of revenue from Centers Therapeutic Research facilities brand-name medicines Institutes invested in R&D

THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE PARIS-SACLAY CLUSTER

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MOULON AREA

1 INSTITUTE FOR INTEGRATIVE BIOLO- 4 INSTITUTE FOR THE DIVERSITY, ECO- 8 CENTRALESUPÉLEC ENGINEERING GY OF THE CELL (FRENCH NATIONAL LOGY AND EVOLUTION OF THE LIVING SCHOOL CENTRE FOR SCIENTIFIC RESEARCH WORLD-IDEEV (PARIS-SUD UNIVERSITY) -CNRS) 9 IT RESEARCH HUB (PARIS-SUD 5 HOUSING, SHOPS, SERVICES, UNIVERSITY) 2 SYNCHROTRON SOLEIL PUBLIC AMENITIES 10 BIOLOGY CHEMISTRY PHARMACY HUB 3 INSTALLATION FOR THE CLIMATE 6 SERVIER PARIS-SACLAY RESEARCH (PARIS-SUD UNIVERSITY) AND THE ENVIRONMENT (FRENCH INSTITUTE ALTERNATIVE ENERGIES AND 11 MOLECULAR SCIENCE ATOMIC ENERGY COMMISSION-CEA) 7 PARIS-SACLAY ÉCOLE NORMALE SUPÉ- INSTITUTE RIEURE GRADUATE SCHOOL

FACTS & FIGURES

265,000 300 430,000 15,000 65,000 10 15% jobs laboratories residents research staff students disciplines of French research gravitating around Paris-Saclay University

A CAMPUS IN ONE OF THE WORLD’S TOP EIGHT INNOVATION CLUSTERS

TECH CITY LONDON SOLKOVO INNOVATION CITY BOSTON PARIS-SACLAY SILICON VALLEY SILICON WADI BEIJING BANGALORE

4 THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE 13 15 12

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ÉCOLE POLYTECHNIQUE AREA

12 EDF TRAINING CAMPUS 14 INSTITUT MINES-TÉLÉCOM 16 ÉCOLE POLYTECHNIQUE SCIENCE&TECH GRADUATE SCHOOL GRADUATE SCHOOL LAB 13 EDF R&D LAB 15 POLICE SUB-PREFECTURE 17 CIVIL AVIATION RADAR

ALREADY BUILT CONSULTATION PROCESS COMPLETED CONSULTATION PROCESS ONGOING

SERVIER PARIS-SACLAY A CAMPUS WITHIN A CAMPUS

The Paris-Saclay public home to international businesses, expertise of other companies, share development agency (EPA) innovative start-ups, universities, facilities, and consolidate strategic is the driving force behind the and prestigious academic and technological partnerships. development of the Paris-Saclay establishments as well as public By choosing to merge its research science and technology cluster and services, housing, and local shops activities in Saclay, the crossroads is promoting it at an international offering an ideal environment for of its four historic bases, the Group level. the Group to prosper. The Servier has chosen a high-level eco-friendly The Servier Group is a close and Paris-Saclay Research Institute will environment where its employees active partner of the Paris-Saclay provide the Group with a vast array can develop and thrive. EPA. The Saclay cluster will be of opportunities to harness the

THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE DYNAMIC PARTNERSHIPS

THE PARIS-SACLAY CLUSTER OFFERS A PROMISING ARRAY OF POTENTIAL FUTURE PARTNERS. THE SERVIER GROUP WILL BE CLOSE TO A WIDE SPECTRUM OF PUBLIC AND PRIVATE STAKEHOLDERS with whom it can build relationships, forge links, and identify opportunities for synergy.

This ambitious vision is perfectly aligned with the Group’s number one objective: boosting research and productivity to obtain maximum coverage of patients’ establishments present on site: and play an active role in local therapeutic needs. the French Alternative Energies events organized by its partners: and Atomic Energy Commission sponsoring the Health Village at This strategy goes hand in hand (CEA), the French National Centre the Paris-Saclay Spring 2019, the with a constant determination for Scientific Research and the EDF Lab and Orange corporate with improving the well-being CentraleSupélec graduate school Campus, Saclay TedX, the Paris- and quality of life of Servier to name but a few. Saclay University Symposium, etc. Group employees by concluding specific partnerships, establishing True to its values, the Servier The Servier Group boasts the sharing of services and Group is consolidating existing a strong academic network contributing actively to the partnerships and has joined the Île and has opened an office in ecosystem. de Science Paris-Saclay nonprofit Cambridge, MA to attract foreign association founded in 1991 to research talent. It is determined The Servier Group has always encourage the establishment of a to play a leading role in the cluster kept its finger on the pulse, being scientific hub with an international thanks to the endeavors of a staff attentive to the world around dimension. of over 150 working on more than it and its various stakeholders. twenty different projects. The Group has already signed At the same time, Servier partnership agreements with intends to organize site visits

6 THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE AN INCUBATOR SUPPORTING START-UPS TO BOOST INNOVATION IN HEALTHCARE

THE INCUBATOR IS THE A veritable hive of innovation CORNERSTONE OF THE covering 1850 m2, the incubator SERVIER PARIS-SACLAY will offer 80 workstations RESEARCH INSTITUTE’S including state-of-the-art OUTWARD-ORIENTED POLICY laboratories and bespoke office THE PLACE TO BE and seeks to become a key space. (WORKING)! player in therapeutic innovation. In addition to the facilities, Working alongside the Servier the incubator is a source The incubator being part of Paris-Saclay Research Institute, of support and services for Servier Paris-Saclay Research it will accommodate start-ups entrepreneurs so that they can Institute is close in both working on innovative scientific channel all their energy into their geographic and strategic and technological projects, projects. Via a network of internal terms, paving the way for enhancing the Group’s and external stakeholders the a constructive conversation visibility, widening its scope, Servier Group provides the legal, between employees. and cementing its strategic financial, and administrative The creation of this incubator positioning. support start-ups need as well as gives everyone an opportunity There will be a unique synergy solid scientific and technological to reach their full potential between dynamic young expertise. and learn new skills. innovative companies and As a committed and proactive The Institute is due to open the Group’s experienced player, Servier is the ideal partner in 2022, allowing time for its pharmaceutical experts providing to initiate and manage innovative development to be tailored to the fast-changing pace fertile ground to accelerate projects which are a source of tomorrow’s innovation. and promote therapeutic research of growth and development. in France and in the international arena.

THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE A DESIGN FAVOURING NEW WAYS OF WORKING

IN ADDITION TO ITS ADDED VALUE FOR THE ENVIRONMENT AND WELL-BEING OF ITS OCCUPANTS, THE PARIS- SACLAY RESEARCH INSTITUTE OFFERS ANOTHER MAJOR BENEFIT: exploring new avenues in workplace relations to encourage the emergence of imaginative new ways to work.

Architects Wilmotte & Associés designed the building around a central ring to break down barriers and promote a collaborative approach between the various project teams and departments. The building embodies synergy and emulation. By housing its research staff under one roof, the cutting-edge technological and is their unwavering commitment Group is laying the foundations digital facilities will encourage to advancing therapies for health for an all-embracing and staff to work in project mode and life. The Servier Group inspiring working environment. and will drive change. wishes to keep their legacy alive and perpetuate what has Designed to facilitate Different areas of the building been achieved. Now, it will be collaborative management will have the names of scientists the turn of the Group’s teams to as well as quick and efficient from different walks of life accelerate research and reinvent dissemination of information, famous for their ground-breaking healthcare. the layout of the institute with its discoveries. What these men diversity of working spaces plus and women all have in common

8 THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE A FACILITY SATISFYING EMPLOYEES, FURTHERING INNOVATION, AND BENEFITING PATIENTS

TOGETHER WE SHARE OUR STRENGTHS It is the Servier Group’s duty to innovate for the benefit of patients, meeting the highest quality standards and offering targeted treatment. Group employees based in the Paris-Saclay cluster will combine their skills to meet healthcare needs.

TOGETHER WE HARNESS OUR SYNERGIES Developing new therapeutic agents requires a broad range of skills. The Paris-Saclay cluster will combine internal know-how with external experience, exploiting the diversity and complementarity of employees to bring added value to therapeutic progress.

TOGETHER WE ADDRESS OUR CHALLENGES For several years now, the Servier Group has been undergoing extensive change to achieve its shared vision in its particular scientific and industrial context and highly competitive environment. The creation of the Servier Paris-Saclay Research Institute testifies to the Group’s ability to address the strategic challenges inherent in therapeutic research.

THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE A SUSTAINABLE BUILDING

TRUE TO ITS ENVIRONMENTAL COMMITMENTS AND CORPORATE SOCIAL RESPONSIBILITY STRATEGY (CSR) covering all stakeholders, the Group has decided to make its Servier Paris-Saclay Research Institute a truly exemplary facility. The Group is aiming for the BiodiverCity® label, coupled with WELL and HQE certifications, for its Servier Paris-Saclay Research Institute thanks to an eco-friendly building, respectful of biodiversity, and the consideration of the well-being of its occupants. The Group’s CSR Department is already working with the partners of the Servier Paris-Saclay Program to factor in the standards set by these certifications and CSR requirements throughout the building cycle.

HIGH ENVIRONMENTAL QUALITY WELL BUILDING STANDARD CERTIFICATION (HQE) CERTIFICATION

HQE is the French certification awarded to The International WELL Building Institute buildings which correspond with the current attributes the WELL Building Standard which state-of-the-art in environmental performance promotes the well-being of employees and energy efficiency. in a tertiary building. It is a global rating system which sets extremely high standards in ten areas: Working towards achieving certification is part of the process of continuous improvement • Air quality • Choice designed to assess building performance, lower • Water quality of materials energy consumption, mitigate environmental • Nourishment • Mental impact, and enhance well-being and comfort. and nutritional well-being The performance of the Institute’s tertiary space quality of food • The WELL certified according to the 2015 version of HQE • Visual comfort Community will be evaluated against four separate but • Thermal comfort • Physical fitness complementary parameters: • Acoustic comfort

• Energy • Health For the Group, this certification is instrumental • Environment • Comfort in contributing to the well-being and performance of the teams working in its tertiary building. As all requirements are factored in from the A healthy workforce is a priority for the Group. outset, the Group is aiming for the highest The Group undertakes to encourage physical possible environmental quality for the Servier fitness, offer healthy, balanced meals, raise Paris-Saclay Program. awareness about health issues, and help ensure a satisfactory work-life balance in line with its CSR strategy on quality of life in the workplace.

10 THE SERVIER PARIS-SACLAY RESEARCH INSTITUTE BIODIVERCITY® LABEL The first international label to include biodiversity in real-estate projects, BiodiverCity® incorporates and promotes nature, plant life, and the living world. It represents a benchmark for ecology and sustainable building. BiodiverCity® bases its evaluation on multiple criteria under four topics: 1 2

COMMITMENT THE PROJECT

Adopting a biodiversity strategic plan tailored to Designing green architecture which makes nature the construction project by analyzing and gaining a priority and adapts amenities to accommodate in-depth knowledge of the biodiversity of the site living things. and its surroundings.

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ECOLOGICAL ADVANTAGES BENEFITS FOR USERS

To create diversified habitats of high ecological Highlighting the advantages of biodiversity, value, which favour local biodiversity, and to offering nature-related services to the occupants ensure continuity between these habitats and of the building and spreading knowledge about those nearby. biodiversity.

In accordance with these and contemplate the local fauna better understand environmental standards, the Servier Paris-Saclay and flora while developing their issues. Research Institute will incorporate knowledge of plant design. nearly 5000 m² of gardens at In order to enhance the value ground level, 9000 m² of green Thanks to this biophilic approach, of the label in the long term roofs, more than 70 plant species, Servier Group employees, as and contribute positively to 100 m² of communal vegetable well as at the nearby Parc des biodiversity, Servier undertakes patch, and hospitable habitats Moulons, will be able to enjoy a to guarantee the ecological such as nesting boxes. relaxing moment in these densely management of these areas for a These wellness areas, vegetated areas. Biodiversity- minimum of 5 years and to carry incorporating outdoor furniture, related events will also be out ecological monitoring by an will enable employees to discover organized to help staff members expert every 3 years.

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