ASIA TDAC AESTHETIC MEDICINE WORLD CONGRESS & Taiwan dermatology Aesthetics conference

10, 11 & 12 MAY 2019 TAIWAN - TAIPEI Convention Centre

Abstract Book

www.euromedicom.com Welcome toTaipei Welcome Taipei To visit

• Taipei 101 Why • Yangmingshan National Park TAIPEI? • Taipei Zoo • Taipei Botanical Garden • Daan Park • National Palace Museum Activities

• South Village #44 • Shilin Night Market Symbol of a free and vibrant democracy, Taipei is a fascinating metropolis with several • Gastronomy: million inhabitants that invites you into a world of amazing contrasts: a mix of the modern Discover Dongpo Pork, Meat Rice Dumplings, and traditional, with a generous dash of energy and friendly smiles. With a strong tendency to Dumplings, adopt the "LOHAS" (Lifestyle Of Health And Sustainability), Taipei is a wonderful city with more Tea ceremony, Xiao Long Bao, etc. than 10,000 aesthetics practitioners, allying business opportunities and a highly-educated population (half of the population speaks English). Apart from advanced medical technology well-known around the world, the city of Taipei also includes a number of important associations Useful information and committees of medical aesthetics professionals working together. • Average temperature in May: 25ûC Moreover, Taiwan has the 3rd largest number of hospitals in the top 200 list, with 14 Taiwanese • Currency: New Taiwan Dollar (NT$) hospitals appearing on the list. In this unique environment, the AWMC, a must-attend event, • Sales tax is included benefits from special expertise with a quality Asian approach. in the listed prices in Taipei City • Be one of the 2,500 expected attendees for this 2nd AMWC Asia edition, already known as Service charge is customary THE event of the year and make your trip to Taipei a most memorable journey. 10% in hotel or restaurant

VENUE ON-SITE REGISTRATION Located in the heart of Taipei and adjacent to the iconic Taipei 101 On-site registration will be available each day of the congress. (which was at one point the tallest building in the world), TICC is The delegate registration fee includes: a very central location, with lots of malls and attractions nearby. Taipei • A badge, a congress bag, a conference book, all the congress International Convention Center (TICC) is located right next to a metro documents and a certificate of attendance to the scientific station. program. www.ticc.com.tw/main_en/index.aspx • Admission to the exhibition area and the conference rooms depending on your choice of registration (CONFERENCE PASS - Taipei International Convention Center (TICC) 2 DAYS or FULL PASS - 3 DAYS) 1 Hsin-Yi Road, Section 5 • Coffee breaks and lunch boxes offered on site (Conference Pass Taipei 11049, Taiwan ROC and Full Pass) Email: [email protected] Tel: +886(2)2725-5200 / Fax: +886(2)2723-2589 ACCOMMODATION www.ticc.com.tw/main_en/index.aspx The information and booking forms of the following recommended hotels can be consulted at WWW.EUROMEDICOM.COM For Post-congress Hands-on Anatomy Workshop (Practical anatomy for injectables & threads), the event will take place at: Pacific Business Hotel Minimally Invasive Surgery Training Center Sparkle Hotel B1F, No. 2, Xuzhou Road Grand Hyatt Hotel Zhongzheng District 100, Taipei City W Hotel (The center is located at B1F of NTUH International Convention Center) Home Hotel These hotels are located in the vicinity of TICC. VISA Please consult Bureau of consular affairs, Ministry of Foreign Affairs, Republic of China (Taiwan) website for detail of visa requirement. https://www.boca.gov.tw/mp-2.html

If you require a visa invitation letter for inclusion with your entry VISA application, please DOWNLOAD it from our site WWW.EUROMEDICOM.COM or contact us at [email protected]

LANGUAGES Official Language: English LEVEL 1 LEVEL 2 LEVEL 3 Welcome

Organization Dear Colleagues and Friends, EuroMediCom Following the great success of the 1st AMWC Asia in 2018, the collaboration 37, avenue de Friedland between EuroMediCom and the Taiwan Dermatological Association Conference 75008 Paris, France (TDAC), & the Taiwan Society for Dermatological and Aesthetic Surgery (TSDAS) Tel: + 33 (0)1 58 56 74 00 has been renewed, with the 2nd edition taking place this year. www.euromedicom.com It is our great honour to welcome you to the 2nd AMWC Asia taking place alongside the 7th Taiwan Dermatology Aesthetic Conference on 10-11-12 May 2019 Congress venue in Taipei, Taiwan. Taipei International Convention Center (TICC) The organizers of AMWC Asia-TDAC aim to bring the best speakers from Taiwan, 1 Hsin-Yi Road, Section 5 Asia and around the world to share their best practices, knowledge and skills. Taipei 11049, Taiwan ROC Moreover, Taipei is a strategic location for AMWC Asia-TDAC, as it is one of AsiaÔs most advanced and modern cities, with a well-developed anti-aging and medical aesthetic market. The geographical location also leverages dynamic growth in both China and Southeast Asia.

AMWC Asia-TDAC will focus on top-notch scientific content, including live demonstrations and practical knowledge sharing, and will bring together doctors and aesthetic practitioners from all over Taiwan and the region. AMWC Asia-TDAC AMWC Asia 2019 (Taiwan) is is poised to become one of the best platforms in Asia for medical aesthetics. PROVISIONALLY COMPLIANT with the MedTech Europe Code We look forward to seeing you in Taipei. of Ethical Business Practice Event reference: EMT14390 AMWC Asia-TDAC Scientific Committee

Scientific Committee

CHIANG Chien-Ping LAN Cheng-Che WU Yu-Hung CHU Chia-Yu LEE Chih-Hung YANG Chih-Hsun CHUNG Wen-Hung LIAO Yi-Hua YANG Hung-Hsu HO Ji-Chen PENG Peter Hsien-Li HSU Nai-Jen TSAI Hsiou-Hsin HUANG Patrick Po-Han WANG Chao-Chin Organizing Committee

CHANG Ying-Jui HUANG Patrick Po-Han TSENG Chung-Jen CHAO Sheau-Chiou LAN Cheng-Che WANG Chao-Chin CHAO Yates Yen-Yu LEE Chih-Hung WANG Wei-Ming CHEN Chi-Chiang LEE Woan-Ruoh WEN Su-Ying CHEN Jau-Shiuh LEE Din-Dar WU Yu-Hung CHEN Yi-Ju LIAO Yi-Hua WU Ying-Chin CHENG Yu-Pin LIN Sung-Jan WU Chieh-Shan CHIANG Chien-Ping LIN Chrang-Shi YANG Chih-Hsun CHU Chia-Yu PENG Peter Hsien-Li YANG Hung-Hsu CHUNG Wen-Hung SHIH I-Hsin YANG Chia-Yi DAI Yang-Shia TSAI Hsiou-Hsin HO Ji-Chen TSAI Ren-Yeu HSU Nai-Jen TSAI Tsen-Fang International DIRECTORS

Prof. CHU Prof. MARINI Prof. YANG Prof. TSAI Dr. HSU Dr. WANG Chia-Yu Leonardo Jason Chih-Hsun Ren-Yeu Nai-Jen Chao-Chin

a TDA'S INTERNATIONAL TAIWANESE CONFERENCE PRESIDENT SCIENTIFIC DIRECTOR SCIENTIFIC DIRECTORS SECRETARY GENERAL International SCIENTIFIC COMMITTEE

ANAND Chytra AVERINA Vladlena BERTOSSI Dario BESINS Thierry Dermatologist Dermatologist Prof. Facial Plastic Surgery Plastic Surgeon India Ukraine Italy France

a

CHUNG Kee Yang GOLDIE Kate GOUT Uliana GUTOP Ekaterina Prof. Dermatology Aesthetic Practitioner Aesthetic Practitioner Dermatologist Korea UK UK Russia

a

KATSAMBAS Andreas MANUSKIATTI Woraphong PIRAYESH Ali Prof. Dermatology Prof. Dermatology Plastic Surgeon Greece Thailand Netherlands

a

ROJANAMATIN Jinda VERNER In�s YAMADA Hidekazu Dermatologist Dermatologist Prof. Dermatology Thailand Israel & Anti-aging Practitioner Japan FACULTY LIST

ARKESTEIJN Walter Medical Aesthetics Industry Eindhoven, Netherlands GOLDIE Kate Aesthetic Practitioner London, UK

ASHOUR Mahran Clinic Manager United Arabs Emirates GRAZIANO Antonio Research Scientist Italy

AVELAR Luiz Plastic & Reconstructive Surgeon Belo Horizente, Brazil GUEVARA Bryan Dermatologist Davao, Philippines

AVERINA Vladlena Dermatologist Kiev, Ukraine HO Ji-Chen Dermatologist Kaohsiung, Taiwan

BANERJEE Antara Biologist/Biochemist Kelambakkam, India HO Wilson Plastic Surgeon Hong Kong

BEKHOR Philip Prof. Dermatology Mont Albert North, Australia HSIAO Cheng-Hsiang Dermatopathologist Taipei, Taiwan

BERMAN Dror Dean Aesthetic Practitioner Leobendorf, Austria HSAIO Jack CEO, Hospital management New Taipei, Taiwan

CALDERHEAD R Glen Laser specialist Goyang, South Korea HSU Chao-Kai Dermatologist Tainan, Taiwan

CHAN Heng-Leong Dermatologist Taipei, Taiwan HSU Che-Hao Dermatologist New Taipei, Taiwan

CHAN Tom Dermatologist Taipei, Taiwan HSU Nai-Jen Dermatologist Tainan, Taiwan

CHANG Chih-Hao Dermatologist Taipei, Taiwan HSU Shawn Hsiu-Cheng Dermatologic Surgeon Changhua, Taiwan

CHANG David Yao-Yu Dermatologist Taipei, Taiwan HU Sindy Dermatologist Taipei, Taiwan

CHANG Hung-Chia Dermatologist Taipei, Taiwan HUANG Allen Yao-Lin Plastic Surgeon Taipei, Taiwan

CHANG Shyue-Luen Dermatologist Taipei, Taiwan HUANG Ching-Hsin Dermatologist Kaohsiung, Taiwan

CHANG Wei-Ting Dermatologist Taipei, Taiwan HUANG Ching-Yu Dermatologist Taipei, Taiwan

CHANG Ying-Jui Dermatologist New Taipei, Taiwan HUANG Hui-Peng Dermatologist Tainan, Taiwan

CHAO Sheau-Chiou Dermatologist Tainan, Taiwan HUANG Jeff Chen-Chieh Dermatologist Taipei, Taiwan

CHAO Yates Yen-Yu Dermatologic Surgeon Taipei, Taiwan HUANG Patrick Po-Han Dermatologist Kaohsiung, Taiwan

CHAUCHARD Claude Anti-aging Practitioner Paris, France HUANG Peter Yao-Chu Plastic Surgeon Taoyuan, Taiwan

CHEN Chun-Bing Dermatologist Taipei, Taiwan HUANG Ying-Chu Dermatologist Taipei, Taiwan

CHEN Chih-Chiang Dermatologist Taipei, Taiwan HUANG Yu-Huei Dermatologist Taipei, Taiwan

CHEN Jau-Shiuh Dermatologic Surgeon Taipei, Taiwan HUANG Yu-Chen Dermatologist Taipei, Taiwan

CHEN Kai-Lung Dermatologist Taipei, Taiwan HUANG Yu-Ming Dermatologist Taipei, Taiwan

CHEN Leslie Yen-Peng Orthodontist Taichung, Taiwan HUANG Yung-Hsueh Dermatologist Changhua, Taiwan

CHEN Pao-Jen Gynecologist Taipei, Taiwan HUI Rosaline Chung-Yee Dermatologist Taipei, Taiwan

CHEN Peter Ruei-Feng Plastic Surgeon Hsinchu, Taiwan HUWANG Chian-Yaw Dermatologist New Taipei, Taiwan

CHEN Yi-Chin Dermatologist Taipei, Taiwan ISRAELI Hadar Aesthetic Practitioner Tel Aviv, Israel

CHEN Yi-Hsing Dermatologist Taipei, Taiwan JUNG Wonsug Anatomist Seoul, South Korea

CHEN Yi-Ju Dermatologist Taichung, Taiwan KAO Chao-Hsing Dermatologist Kaohsiung, Taiwan

CHENG Carl Kuo-Liang Dermatologist Taipei, Taiwan KASRAEE Behrooz Dermatologist Grand-Lancy, Switzerland

CHENG Charles Aesthetic Practitioner Vancouver, Canada KENCANAWATI Anne Carolina Aesthetic Practitioner Jakarta Selatan, Indonesia

CHI Ching-Chi Prof. Dermatology Taoyuan, Taiwan KIM Hong-Seok Dermatologist Cheongju, South Korea

CHI Min-Hui Dermatologist Keelung, Taiwan KING Walter Prof. Plastic Surgery Hong Kong

CHIU Hsien-Yi Dermatologist Hsinchu, Taiwan KO William Wei-Chi Dermatologist Taipei, Taiwan

CHIU Pin-Chi Dermatologist Taichung, Taiwan KONTUREK Peter C. Internal Medicine Saalfeld, Germany

CHIU Yu-Hsun Facial Plastic Surgeon Taipei, Taiwan KUO Hsiao-Ling Rheumatologist Taipei, Taiwan

CHO Yung-Tsu Dermatologist Keelung, Taiwan KWON Han Jin Aesthetic Surgeon Seoul, South Korea

CHRISTIE Andrew R. Aesthetic Practitioner Terrey Hills, Australia LAI David Ying Ching Anti-aging Practitioner Hong Kong, China

CHU Chia-Yu Prof. Dermatology Taipei, Taiwan LAI Feng-Jie Dermatologist Tainan, Taiwan

CHUANG Celina Ying-Yen Dermatologist New Taipei, Taiwan LAI Po-Ju Dermatologist Taichung Taiwan

CHUNG Kee-Yang Prof. Dermatology Seoul, South Korea LAM Phoebe Kar Wai Cosmetic Surgeon Hong Kong

CHUNG Wen-Hung Prof. Dermatology Taipei, Taiwan LAN Cheng-Che Prof. Dermatology Kaohsiung, Taiwan

D'ALESSIO Patrizia Internal Medicine Villejuif, France LAU Katie Dermatologist Hong Kong

DAI Yang-Shia Dermatologist Taipei, Taiwan LEE Geun-Soo Dermatologist Seoul, South Korea

DECANGCHON Francis Aesthetic Surgeon Quezon City, Philippines LEE Mei-Ching Dermatologist Taipei, Taiwan FACULTY LIST

LEE Woan-Ruoh Prof. Dermatology New Taipei, Taiwan SHEEN Yi-Shuan Dermatologist Taipei, Taiwan

LEE Yung-Yi Dermatologist Taipei, Taiwan SHEU Hamm-Ming Prof. Dermatology Tainan, Taiwan

LEYLEK Ozgur Gynecologist Istanbul, Turkey SHIH I-Hsin Dermatologist Taipei, Taiwan

LI Chien-Nien Dermatologist Taipei, Taiwan SHIH Tsung-Hsien Dermatologist Kaohsiung, Taiwan

LI Chih-Wei Dermatologist New Taipei, Taiwan SOFRA-WEISS Xanya Anti-Aging Practitioner Tai Po, Hong Kong

LI Jack Yu-Chuan Prof. Dermatology Taipei, Taiwan STANKOVIC Nenad Aesthetic Practitioner Belgrade, Serbia

LI Ko-Jen Rheumatologist Taipei, Taiwan SUN Pei-Lun Dermatologist Taipei, Taiwan

LIANG Ben Chung-Pin Dermatologist Taipei, Taiwan TING Sze-Wen Dermatologist Taipei, Taiwan

LIAO Yi-Hua Dermatologist Taipei, Taiwan TSAI Ren-Yeu Dermatologic Surgeon Taipei, Taiwan

LIM Joyce Dermatologist Singapore TSAI Tsen-Fang Prof. Dermatology Taipei, Taiwan

LIM Ting Song Aesthetic Practitioner Petaling Jaya, Malaysia TSAI Ya-Chu Dermatologist New Taipei, Taiwan

LIN Chia-Chi Oncologist Taipei, Taiwan TSENG Chung-Jen Dermatologist Taipei, Taiwan

LIN Chrang-Shi Prof. Dermatology Taipei, Taiwan TSENG Fang-Wen Dermatologist Taipei, Taiwan

LIN Jeng-Hsien Dermatologist Kaohsiung, Taiwan TSENG Han-Chi Dermatologist Kaohsiung, Taiwan

LIN Liang-Chen Dermatologist Hsinchu, Taiwan TSENG Jonathan Te-Peng Dermatologist Taipei, Taiwan

LIN Shang-Li Dermatologist New Taipei, Taiwan TSENG Yu-Ju Dermatologist Taipei, Taiwan

LIN Tzu-Kai Dermatologist Hualien, Taiwan TU Wei-Ting Dermatologist Taipei, Taiwan

LIN Yi-Ting Dermatologist Taipei, Taiwan VAN EIJK Tom Aesthetic Practitioner Laren, Netherlands

LIU Hen-Yu Research Scientist Taipei, Taiwan VIZINTIN Zdenko Laser & Light Therapy Industry Ljubljana, Slovenia

LIU Li-Lin Dermatologist Kaohsiung, Taiwan VOROPAI Daria Aesthetic Practicioner London, United Kingdom

LU Chun-Wei Dermatologist Taipei, Taiwan WANG Chao-Chin Dermatologist Kaohsiung, Taiwan

LU Po-Hsuan Dermatologist Taipei, Taiwan WANG Chao-Huei Dermatologist Taipei, Taiwan

LU Sophie Pei-Hsuan Dermatologic Surgeon Taipei, Taiwan WANG Cheng-Kun Dermatologist Taipei, Taiwan

LU Victoria Ching-I Dermatologist Taipei, Taiwan WANG Jann-Yuan Internal Medicine Taipei, Taiwan

MANUSKIATTI Woraphong Prof. Dermatology Banghok, Thailand WANG Jen-Yu Dermatologist Taipei, Taiwan

MARINI Leonardo Prof. Dermatology Trieste, Italy WANG Shiou-Han Dermatologist Taipei, Taiwan

MARTIN Druanne Senior Publisher Philadelphia, United States WANG Wei-Ming Prof. Dermatology Taipei, Taiwan

MENDEZ ESPANA Mauricio Dermatologist San Diego, USA WANG Yen-Jen Dermatologic Surgeon Taipei, Taiwan

MIYATA Nariaki Plastic Surgeon Tokyo, Japan WANITPHAKDEEDECHA Rungsima Dermatologist Bangkok, Thailand

MOEY Christie Aesthetic Practitioner Kuala Lumpur, Malaysia WEI Lin-Hung Dermatologist Taipei, Taiwan

NADELA Rosalina Dermatologist San Juan Philippines WENG Hao-Jui Dermatologist Taipei, Taiwan

NG Chau-Yee Dermatologist Taipei, Taiwan WONG Sky Tin-Hau Aesthetic Surgeon Hong Kong

NOVAKOV Aleksandra Gynecologist Novi Sad, Serbia WU Jennifer Dermatologist Taipei, Taiwan

PARK Young-Woon Dermatologist Seoul, South Korea WU Nan-Lin Dermatologist Taipei, Taiwan

PATHAK Surajit Biologist/Biochemist Chennai, India WU Ying-Chin Dermatologist Taipei, Taiwan

PENG Peter Hsien-Li Dermatologist Kaohsiung, Taiwan WU Yu-Hung Dermatologist Taipei, Taiwan

PENG Yu-Pin Dermatologist Taipei, Taiwan YANG Chin-Yi Dermatologist Taipei, Taiwan

PIRAYESH Ali Plastic Surgeon Amsterdam, Netherlands YANG Ching-Sheng Dermatologist Taipei, Taiwan

RAVICHANDRAN Simon ENT & Facial Plastic Surgeon Bothwell, United Kingdom YANG Jason Chih-Hsun Prof. Dermatology Taipei, Taiwan

ROJANAMATIN Jinda Dermatologist Bangkok, Thailand YONEI Yoshikazu Anti-Aging Practitioner Kyoto, Japan

SAMIZADEH Souphiyeh Dental Surgeon London, UK YU Peter Dermatologist Taipei, Taiwan

SCHERER Max-Adam Plastic Surgeon Moscow, Russia ZABNENKOVA Olga Dermatologist Moscow, Russia

SEO Suk Bae Dermatologist Seoul, South Korea ZHOU Guoyu Prof. Facial Plastic Surgery Shanghai, China

SERRANO Gabriel Dermatologist Valencia, Spain

SHAH Falguni Dermatologist Mumbai, India PRE-CONGRESS Course FRIDAY 10 MAY

ADVANCED INJECTABLES: CUTTING-EDGE TECHNIQUES BY MAESTROS VS POTENTIAL OF AI Room 201ABC - Level 2

PHLEBOLOGY WORKSHOP Room 201D - Level 2

NAIL BRACE WORKSHOP Room 201D - Level 2 Friday 10 MAY-

8.30 - 17.30 ADVANCED INJECTABLES: CUTTING-EDGE TECHNIQUES BY MAESTROS VS POTENTIAL OF AI ROOM 201ABC - Level 2 COURSE DIRECTORS

Dr. WANG Chao-Chin Dr. WANITPHAKDEEDECHA Rungsima

Overview

This full day comprehensive pre-congress course is dedicated to those who wish to advance both the knowledge and techniques in the field of injectables. The attendees will have the opportunity to learn: ¥¥The latest updates of injectables techniques and the advanced knowledge of practical anatomy ¥¥When to go beyond injectables for difficult cases and what would be the optimal practice ¥¥Unparalleled learning experience from maestros in holistic patient assessment, planning of treatment and close observation of their cutting-edge techniques of treatment

This course will further examine the future of Artificial Intelligence (AI) in aesthetic medicine through in-depth discussions: ¥¥Patient assessment using commercially available AI technology with a debate on its impact, benefits until possible aid in our practice ¥¥Head-to-head comparison of the assessment and simulated result of treatment between human maestros and AI

9.00 14.00 LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS ADVANCEMENT OF AI TECHNOLOGY 10.30 15.30

Chair: WANG Chao-Chin, WANITPHAKDEEDECHA Rungsima Chair: WANG Chao-Chin, WANITPHAKDEEDECHA Rungsima • Botulinum neurotoxin formulations: overcoming the confusion • • Live Demo 1 • ZABNENKOVA Olga, Russia SOUPHIYEH Samizadeh, UK • Live Demo 2 • GOLDIE Kate, UK • A review of emerging toxins in Asia • HUANG Patrick Po-Han, Taiwan • Live Demo 3 • LIM Ting Song, Malaysia • Botulinum toxin A: A step from beauty to remedy • • Impact and application of AI technology in current aesthetic practice • NADELA Rosalina, Philippines WANG Chao-Chin, Taiwan • Regional nerve block in practice • ROJANAMATIN Jinda, Thailand • Integration of AI technology in my aesthetic practice • LI Chih-Wei, Taiwan • Live marking for botulinum toxin • NADELA Rosalina, Philippines • AI basics and healthcare applications • LI Jack Yu-Chuan, Taiwan • Live marking for nerve block & botulinum toxin • ROJANAMATIN Jinda, Thailand

11.00 BEYOND INJECTABLES: 16.00 LIVE DEMONSTRATIONS ON RANDOMLY SELECTED MODELS: 13.00 WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES 17.30 HUMAN MAESTROS VS AI Chair: ROJANAMATIN Jinda, WANG Chao-Chin Chair: ZABNENKOVA Olga, WANITPHAKDEEDECHA Rungsima The experts will be assigned to perform a treatment on the patients • Managing aesthetic patients with personalization (I) and (II) • randomly selected by the scientific team AVELAR Liuz, Brazil • Treating the mature patient, what has the highest impact with least product • VOROPAI Daria, UK • Target Specific Sandwich Technique (TSST): A more efficient way to deliver dermal fillers • LIM Ting Song, Malaysia • Restoring the anchoring complex for better facial contouring • AVELAR Luiz GOLDIE Kate RAVICHANDRAN Simon LIM Ting Song, Malaysia Brazil UK UK • 5 technologies for precise jawline: BoTNA, threads, fillers, mesotherapy • ZABNENKOVA Olga, Russia • “Tête à tête” technique for perioral rejuvenation • ZABNENKOVA Olga, Russia • How to use HA and CaOH dermal fillers to best effect when treating the WANITPHAKDEEDECHA Rungsima TSENG Fang-Wen jawline and chin • RAVICHANDRAN Simon, UK Thailand Taiwan Friday 10 MAY-

9.00 - 12.30 COURSE INSTRUCTORS PHLEBOLOGY WORKSHOP Dr. CHANG Yao-Yu ROOM 201D - Level 2 Prof. YANG Jason Chih-Hsun

Overview

This workshop will provide an overview introduction to the main principles of phlebology and sclerotherapy of varicose veins.

After completing this workshop, participants will be able to describe the anatomy of venous reflux, identify the advantages and disadvantages of various sclerosing agents and foaming technique, and identify leg veins, spider veins, and truncal varicosities.

The ultimate goal is to enable clinicians to determine the appropriate use of sclerotherapy, laser, phlebectomy, or endovenous ablation for each patient. Instructors will perform live demonstrations of patient evaluation, sclerosing foam production, spider vein injection, and ultrasound-guided injection techniques.

Participants will have the opportunity to perform ultrasound exams and practice sclerotherapy on simulation pads.

Moderators: YANG Jason Chih-Hsun

9.00 - 9.20 LOWER LEG VENOUS ANATOMY & PATHOPHYSIOLOGY ¥ CHANG Yao-Yu, Taiwan

9.20 - 9.40 DUPLEX ULTRASOUND EXAMINATION ¥ CHANG Yao-Yu, Taiwan

9.40 - 10.10 HANDS-ON: ULTRASOUND EXAMINATION ¥ All Faculty

10.10 - 10.30 SCLEROTHERAPY ¥ CHANG Yao-Yu, Taiwan

10.30 - 11.00 ¥ COFFEE BREAK

11.00 - 11.20 COMPLICATIONS OF SCLEROTHERAPY ¥ CHANG Yao-Yu, Taiwan

11.20 - 11.50 HANDS-ON SCLEROTHERAPY ¥ All Faculty

11.50 - 12.10 ENDOVENOUS PROCEDURES OVERVIEW ¥ YANG Jason Chih-Hsun, Taiwan

12.10 - 12.30 WHAT'S NEW IN ENDOVENOUS PROCEDURES ¥ YANG Jason Chih-Hsun, Taiwan Friday 10 MAY-

13.30 - 17.30 COURSE COORDINATOR NAIL BRACE WORKSHOP Dr. LEE Yung-Yi ROOM 201D - Level 2

Overview

Nail brace is a non-invasive treatment modality for patients with ingrown nails. The less invasive strategy is a trend in medicine. It provides an option for people who are afraid of nail surgery itself or complication brought by operation.

Why do we consider nail brace for ingrown nails? Simple nail avulsion is mostly performed by many general surgery physicians. However, it will cause a high recurrence rate. Combination of nail avulsion and adequate matricectomy can achieve a satisfying outcome. However, patients with underlying diseases including diabetes, venous insufficiency, or cardiovascular disease under anti-coagulant medication are worried about poor wound healing. In addition, some patients are nervous about nail surgery, especially among children.

What can I expect from the training course? You will get the full knowledge about ingrown nails and concept of nail brace. Based on the information, you can explain the nail brace well to your patients. Afterwards, experienced doctors will help you to install the nail brace hand by hand. After the workshop, you can get the certificate of participation.

What type of hands-on material will the course provide? We will prepare the instruments and provide you one set of free metal wires. Participants will practice installing the nail braces each other.

13.30 - 13.45 THE CAUSES AND DEVELOPMENT OF INGROWN NAILS ¥ LEE Yung-Yi, Taiwan

13.45 - 14.00 SURGICAL TREATMENT OF PARONYCHIA ¥ WU Jennifer, Taiwan

14.00 - 14.15 CONSERVATIVE TREATMENT OF PARONYCHIA ¥ CHANG Chih-Hao, Taiwan

14.15 - 14.30 THE CONCEPT OF DIFFERENT NAIL BRACES ¥ CHEN Yi-Chin, Taiwan

14.30 - 15.00 THE PRACTICAL STEPS AND TIPS OF NAIL BRACE ¥ TSENG Jonathan Te-Peng, Taiwan

15.00 - 15.15 COMBINATION THERAPY BETWEEN NAIL BRACE AND OTHER TREATMENTS ¥ HUANG Ching-Yu, Taiwan

HANDS-ON: NAIL BRACE INSTALLATION ¥ LEE Yung-Yi, WU Jennifer, CHANG Chih-Hao, CHEN Yi-Chin, 15.15 - 17.30 TSENG Jonathan Te-Peng, HUANG Ching-Yu Schedule SATURDAY 11 MAY

ROOM 103 PLENARY HALL ROOM 201EF ROOM 102 ROOM 101A ROOM 201ABC Level 1 Level 3 Level 2 Level 1 Level 1 Level 2 (Sessions in Mandarin)

Anatomy for Aesthetic Drug Reaction Hair & Nails Forum Treatments Cosmeceuticals/ Drug Allergy Updates in 8.30 Latest updates in Analysis with tips & What's new & Cancer Dermatopathology 10.30 hair regeneration pearls for injectables in Skin Care? Treatment-Related (Mandarin) & nail diseases & threads Skin Reaction

10.30 COFFEE BREAK 11.00

Male VS Female Dermatologic & Beautification Cosmetic Surgery Focus Session on Updates in the between male Stimulating Comprehensive 11.00 Pigmentation Management of Skin & female in Injectables & concise Psoriasis 13.00 Managing Malignancy the 21st century What's new? methods for Melasma (Mandarin) DESKTOPComputer assisted improving your DEMO results

13.00 LUNCH BREAK 14.00

Teledermatology Cutting Edge (Mandarin) 14.00 Art & Science Sponsored in Anti Aging Acne and 16.00 for Thread-lifts (I) Symposium Stress, LED, Rosacea Forum Updates in Healthy Aging Genodermatoses (Mandarin)

16.00 COFFEE BREAK 16.30

Art & Science Sponsored Snapshots for Thread-lifts (II): Practical 16.30 Symposium Expert's advices of Recent Threads in Dermatoscopy 18.00 on rejuvenation Advances in Skin combination (Mandarin) Patient Therapeutics treatment Management

ROOM 201D NORTH LOUNGE Level 2 Level 3

9.30 Sponsored Symposium 10.30 Sponsored Symposium 10.30 COFFEE BREAK 11.00 Sponsored Symposium

11.00 Sponsored Symposium Sponsored Symposium 13.00

13.00 LUNCH SYMPOSIUM 14.00 LUNCH SYMPOSIUM Sponsored Symposium 14.00 16.00 Sponsored Symposium Sponsored Symposium

16.00 COFFEE BREAK 16.30

16.30 Sponsored Symposium 17.30 Schedule SUNDAY 12 MAY

ROOM 103 PLENARY HALL ROOM 201EF ROOM 102 ROOM 101A ROOM 201ABC Level 1 Level 3 Level 2 Level 1 Level 1 Level 2 (Sessions in Mandarin) Recent Updates & Trends in Aesthetic Interface Between Regenerative Rheumatology & Medicine & Surgery Updates in Dermatology Molecular 8.30 (Mandarin) Opening Ceremony Diagnosis and 10.30 Non-Invasive Skin Emerging Energy- When and How to use Showcase of Diagnostic Tools based Devices Biologic and Small injectables Picosecond lasers: Molecule Therapies Upper Face Sponsored Where are we now Symposium (Mandarin) 10.30 COFFEE BREAK COFFEE BREAK 11.00

Showcase of injectables Top Clinical Urticaria and Pruritus Cases Upper Face Ultimate (Mandarin) 11.00 VIDEO Emerging Energy- Interactive LIVE DEMO Feminine Photomedicine 13.00 based Devices Discussion Rejuvenation Showcase of Vitiligo injectables Rising Stars (Mandarin) Midface & Nose Forum 13.00 LUNCH BREAK 14.00 Showcase of From Bench to injectables Bedside Midface & Nose Regenerative Body Contouring (Mandarin) 14.00 VIDEOLIVE DEMO Updates in Medicine Current & future Atopic Dermatitis 16.00 Vascular Treatment Cell Therapies & New Insight and Showcase of trends Microbiome Discovery in Clinical injectables Practices Lower Face & Neck (Mandarin) 16.00 COFFEE BREAK 16.30

Focus Session Showcase of Skin Infection and Pitfalls to Avoid on Nose 16.30 injectables Pediatric Sexually Transmitted Scar Forum in Aesthetic Beautification 18.00 Lower Face & Neck Dermatology Diseases Procedures VIDEOLIVE DEMO Practice (Mandarin) Marketing

ROOM 201D NORTH LOUNGE Level 2 Level 3

9.30 Sponsored Symposium 10.30 Sponsored Symposium 10.30 COFFEE BREAK 11.00

Sponsored Symposium 11.00 Sponsored Symposium 13.00 Sponsored Symposium Sponsored Symposium Sponsored Symposium

13.00 LUNCH SYMPOSIUM LUNCH SYMPOSIUM 14.00 LUNCH SYMPOSIUM

Sponsored Symposium Sponsored Symposium 14.00 16.00 Sponsored Symposium

16.00 COFFEE BREAK 16.30

16.30 17.30 Saturday 11 MAY PLENARY HALL Level 3

8.30 - 10.30 ANATOMY FOR AESTHETIC TREATMENTS: ANALYSIS WITH TIPS & PEARLS FOR INJECTABLES & THREADS

Chair: JUNG Wonsug, SOUPHIYEH Samizadeh • Anatomy for aesthetic treatments: Upper face JUNG Wonsug, South Korea • Anatomy of the forehead fat compartments and techniques for safe and effective rejuvenation RAVICHANDRAN Simon, UK with dermal fillers • Anatomy for aesthetic treatments: Midface JUNG Wonsug, South Korea • Perioral and neck anatomy for non-surgical enhancement and beautification SOUPHIYEH Samizadeh, UK • Understanding the aging process on facial bone structures AVELAR Luiz, Brazil • Essential facial anatomy in aesthetic practice ROJANAMATIN Jinda, Thailand

11.00 - 13.00 MALE VS FEMALE: BEAUTIFICATION BETWEEN MALE AND FEMALE IN THE 21ST CENTURY DESKTOPComputer assisted DEMO

Chair: TSENG Fang-Wen, VOROPAI Daria • The sexual dimorphism in facial bone structures AVELAR Luiz, Brazil • The main differences in Male vs Female correction AVERINA Vladlena, Ukraine • Men's contour enhancement by botulinum toxin and fillers WANITPAKDEEDECHA Rungsima, Thailand • Practical pearls on how to make male patients more handsome (instead of prettier) with TSENG Fang-Wen, Taiwan injectables • Masculine lower third: How to achieve the best result? AVERINA Vladlena, Ukraine • Feminizing male faces in transgenders, what can we achieve? VOROPAI Daria, UK • Male cosmetics: Fashion or Necessity? CHIU Pin-Chi, Taiwan • Computer assisted Demo LI Chih-Wei, Taiwan

ROOM 102 Level 1

11.00 - 13.00 STIMULATING INJECTABLES: WHAT'S NEW?

Chair: HUANG Jeff Chen-Chieh, HSU Nai-Jen • Collagen stimulators: Where are we and how do we choose? HUANG Jeff Chen-Chieh, Taiwan • Topic to be announced GOLDIE Kate, UK • The optimal reconstruction of injectable PLLA HSU Nai-Jen, Taiwan • Simplified step-by-step injectable PLLA treatment (4S treatment) strategy with cannulas LIN Liang-Chen, Taiwan for anti-aging • A new development of injectable polylatic acid (PLA) and clinical experience sharing WONG Sky Tin-Hau, Hong Kong • Injectable PLLA in body contouring AVELAR Luiz, Brazil • Complications of a PCL-based dermal filler: Causes, management, preventions and their incidence LIN Shang-Li, Taiwan rate from review of 1111 treatments • Complications of collagen stimulation filler and their treatments HSU Nai-Jen, Taiwan

17.30 - 18.00 PATIENT MANAGEMENT

• How can we improve consultation technique with NLP (Neuro-Linguistic Programming)? STANKOVIC Nenad, Serbia • How to handle unhappy patients ASHOUR Mahran, United Arabs Emirates Saturday 11 MAY ROOM 201EF Level 2

8.30 - 10.30 HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES

Chair: CHAUCHARD Claude, TSAI Ren-Yeu • Androgenic alopecia: Updates TSAI Ren-Yeu, Taiwan • Hair loss: how to read the hormonal profile to understand the mechanism and future treatment to CHAUCHARD Claud, France stop the process and help hair regrowing • LED photo-biomodulation and carboxytherapy in non scarring alopecia MARINI Leonardo, Italy • The role of 830 nm LED low level light therapy for female pattern baldness: Hope or Hype? CALDERHEAD R Glen, South Korea • Basic knowledge for hair research CHEN Chih-Chiang, Taiwan • Non-surgical therapy for ingrown nail and pincer nail HUANG Ching-Yu, Taiwan • The clinical application of nail brace according to different types and charateristics of HUANG Yu-Chen, Taiwan ingrown nails

11.00 - 13.00 FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA

Chair: HU Sindy, MENDEZ ESPANA Mauricio • Melasma: An up-to-date comprehensive review and the application of in vivo imaging LIAO Yi-Hua, Taiwan • Chemical peels and melasma: What works? NADELA Rosalina, Philippines • Topical and oral combination therapy with tranexamic acid in melasma treatment MENDEZ ESPANA Mauricio, USA • Micro-needling & melasma – delivering innovative and effective patient solutions CHRISTIE Andrew R., Australia • Combination treatment of 755nm alexandrite picosecond laser and microneedle pulsed MOEY Christie, Malaysia radiofrequency in treating recalcitrant melasma • A novel melasma treatment of applications of picolaser assisted drug delivery CHENG Carl Kuo-Liang, Taiwan • The efficacy in treatment of facial melasma with Thulium 1927-nm fractional laser-assisted WANITPHAKDEEDECHA Rungsima, Thailand topical tranexamic acid delivery • The clinically proven superior benefits / risks balance of cysteamine compared to KASRAEE Behrooz, Switzerland Kligman's formula

14.00 - 16.00 ART & SCIENCE FOR THREAD-LIFTS (I)

Chair: STANKOVIC Nenad, WANG Chao-Huei • Anatomic and mechanical considerations in facial thread-lift with absorbable threads STANKOVIC Nenad, Serbia • Case selection and one year follow-up of multiple straight-line-vector protocol of coned threads LIN Shang-Li, Taiwan • Forehead lifting, glabella and nasolabial wrinke treatment with octotwist PDO & PCL KWON Han Jin, South Korea bradied thread • Abdominal shaping using long mono & tornado threads KWON Han Jin, South Korea • Subzygomatic thread lifting: Direct method to treat sagging buccal fat pad LIANG Ben Chung-Pin, Taiwan • The surgical anatomy and deep plane thread lift of the buccal fat pad WANG Chao-Huei, Taiwan • Complications from absorbable threads following thread-lift for facial rejuvenation STANKOVIC Nenad, Serbia

16.30 - 18.00 ART & SCIENCE FOR THREAD-LIFTS (II): THREADS IN COMBINATION TREATMENT

Chair: AVERINA Vladlena, DECANGCHON Francis • Strategies and rationale of combining threads and fillers in facial rejuvenation LIN Shang-Li, Taiwan • Thread lift and filler injection combination treatment PENG Peter Hsien-Li, Taiwan • The Dual Lift technique: Restoring the lower face curvature in Asian with optimal combination of WANG Chao-Chin, Taiwan cog threads and soft tissue fillers • Threads in combine neck treatment AVERINA Vladlena, Ukraine • Non-surgical Thread Rhinoplasty: Tips & Pearls DECANGHON Francis, Philippines Saturday 11 MAY ROOM 101A Level 1

8.30 - 10.30 COSMECEUTICALS / WHAT'S NEW IN SKIN CARE?

Chair: AVERINA Vladlena, CHIU Pin-Chi • Cosmeceuticals: FACTS behind SCIENCE CHIU Pin-Chi, Taiwan • Functional relationship between skin barrier and cosmetics KIM Hong-Seok, Korea • Cosmeceuticals: Do we need home peels? AVERINA Vladlena, Ukraine • How to prescribe moisturizers according to skin types KIM Hong-Seok, Korea • Infusion of active substances wth micro-needling – creating procedural safety CHRISTIE Andrew R., Australia • How to reduce energy-based devices risk by proper skin care regimen CHIU Pin-Chi, Taiwan • Fighting fibroblasts senescence SERRANO Gabriel, Spain

11.00 - 13.00 DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS

Chair: CHUNG Kee Yang, SCHERER Max-Adam • The boundary between non-surgical and surgical intervention on lower face contouring? CHEN Peter Ruei-Feng, Taiwan • Facial fat grafting how I do it DECANGCHON Francis, Philippines • Pan-facial rejuvenation with liposculpture, fat grafting and thread lift LU Sophie Pei-Hsuan, Taiwan • Dermatologic mid face surgery-from reconstruction to facelift HSU Shawn Hsiu-Cheng, Taiwan • MUST-lift: new technique of combination face / neck surgery with elastic permanent threads SCHERER Max-Adam, Russia • Surgical anatomy of the eyelids and techniques for antiaging CHUNG Kee Yang, South Korea • 830 nm LED-LLLT accelerates wound healing in human subjects: A fully randomized, double CALDERHEAD R Glen, South Korea blinded and controlled trial in a standardized wound

14.00 - 16.00 COSMECEUTICALS / WHAT'S NEW IN SKIN CARE?

Chair: LAI David Ying Ching, D’ALESSIO Patrizia • Let's reduce glycative stress, a risk factor for skin aging YONEI Yoshikazu, Japan • Wnt Signaling: a principal regulatory pathway in controlling aging process in human BANERJEE Antara, India • Nutrition and cosmeceuticals delaying skin aging D’ALESSIO Patrizia, France • The two metabolically secrets for losing weight where you need and never feel hungry CHAUCHARD Claude, France • Hormonal replacement in male menopause CHAUCHARD Claude, France • Preventive oncology in antiaging medicine practice LAI David Ying Ching, Hong Kong • Health and fitness by combating hormonal decline, compromised metabolism, and toxicity SOFRA Xanya, Hong Kong • Sexual anti-aging: Safe methods to boost energy and sexual performance in old age SOFRA Xanya, Hong Kong

16.30 - 18.00 EXPERT'S ADVICES ON REJUVENATION

Chair: CHENG Carl Kuo-Liang, LIM Ting Song • Paradigm shift in dermal fillers use: moving away from Volume Based Injections (VBI) LIM Ting Song, Malaysia • Different employments of focused ultrasound to different aging morphotypes in Asians HUANG Patrick Po-Han, Taiwan • IR Laser photothermal tissue pre-conditioning before HA fillers helps to optimize and prolong their MARINI Leonardo, Italy clinical effects • Asia nasal labial fold treated with microneedling radiofrequency: A theory beyond volumizing and CHENG Carl Kuo-Liang, Taiwan tightening • How to optimize combined treatment effects of facial skin tightening with injectables by age KO William Wei-Chi, Taiwan segmentation Saturday 11 MAY ROOM 201ABC Level 2

8.30 - 10.30 DRUG REACTION: DRUG ALLERGY & CANCER TREATMENT-RELATED SKIN REACTION

Moderator: CHUNG Wen-Hung • Clinical presentations and management of chemotherapy induced skin and hair disorders WU Jennifer, Taiwan • Skin toxicities related to EGFR inhibitor treatments CHEN Kai-Lung, Taiwan • Management of EGFR inhibitors induced nail disorders LU Chun-Wei, Taiwan • Immune-related adverse skin reactions induced by anticancer immune checkpoint blockade CHEN Chun-Bing, Taiwan

11.00 - 13.00 PSORIASIS

Moderator: HUANG Yu-Huei, TSAI Tsen-Fang • Gut micorbiota in psoriasis CHEN Yi-Ju, Taiwan • Psoriasis treatment: Interleukin and anti-interleukin TSAI Ya-Chu, Taiwan • Predictors of time to relapse following withdrawal of biologic therapy in patients with psoriasis CHIU Hsien-Yi, Taiwan who reached remission while on treatment • Autoimmune comorbidities in psoriatic disease: A long forgotten domain CHI Ching-Chi, Taiwan

14.00 - 16.00 ACNE AND ROSACEA FORUM

Moderator: LEE Woan-Ruoh, WU Nan-Lin • Photodynamic therapy for inflammatory acne treatment CHUANG Celina Ying-Yen, Taiwan • How to treat rosacea better by holistic approach CHIU Pin-Chi, Taiwan • Topical Ivermectin: A new hope, a new challenge HUANG Yu-Ming, Taiwan • The clinical evaluation and the treatment of post-adolescent acne in women LU Po-Hsuan, Taiwan

16.30 - 18.00 SNAPSHOTS OF RECENT ADVANCES IN SKIN THERAPEUTICS

Moderator: CHAN Heng-Leong • Advances in Skin Therapeutics: Acne and rosacea HUI Rosaline Chung-Yee, Taiwan • Advances in Skin Therapeutics: Psoriasis HUANG Yu-Huei, Taiwan • Advances in Skin Therapeutics: Skin surgery CHANG David Yao-Yu, Taiwan • Advances in Skin Therapeutics: Eczema and atopic dermatitis LIN Tzu-Kai, Taiwan Saturday 11 MAY Sessions in Mandarin ROOM 103 Level 1

8.30 - 10.30 UPDATES IN DERMATOPATHOLOGY (Mandarin)

Moderator: WU Yu-Hung • Many faces of cutaneous lupus erythematosus WU Yu-Hung, Taiwan • Histologic mimics of basal cell carcinoma HSIAO Cheng-Hsiang, Taiwan • The update on blistering disorders HSU Chao-Kai, Taiwan • Tropical and marine dermatology: What lies beneath? GUEVARA Bryan, Philippines

11.00 - 13.00 UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (Mandarin)

Moderator: CHEN Jau-Shiuh, LIAO Yi-Hua • Risk factors for recurrence in Asian localized melanoma CHUNG Kee Yang, Korea • Melanoma: Epidemiology, diagnosis and outcomes SHEEN Yi-Shuan, Taiwan • Surgical treatment of melanoma CHEN Jau-Shiuh, Taiwan • Combined negative pressure wound therapy and eidermal grafting in treating acral melanoma WANG Yen-Jen, Taiwan • Immunotherapy in malignant melanoma LIN Chia-Chi, Taiwan • Targeted therapy for malignant melanoma LIAO Yi-Hua, Taiwan

14.00 - 15.00 TELEDERMATOLOGY (Mandarin)

Moderator: LI Jack Yu-Chuan • Teledermatology in Taiwan, where to begin? LI Jack Yu-Chuan, Taiwan • The new telemedicine laws and its impact to teledermatology practice in Taiwan HSAIO Jack, Taiwan

15.00 - 16.00 UPDATES IN GENODERMATOSES (Mandarin)

Moderator: CHAO Sheau-Chiou • Diagnosis of inherited epidermolysis bullosa in Taiwan TU Wei-Ting, Taiwan • What's new of genodermatosis? HSU Chao-Kai, Taiwan

16.30 - 18.00 PRACTICAL DERMATOSCOPY (Mandarin)

Moderator: CHANG Ying-Jui, YANG Jason Chih-Hsun • Practical dermoscopy beyond pigmented lesions CHI Min-Hui, Taiwan • The evolution of dermoscopy: My journey CHIU Pin-Chi, Taiwan • Dermatoscopic pearls for the private-practice dermatologists YANG Jason Chih-Hsun, Taiwan Sunday 12 MAY

PLENARY HALL Level 3

8.30 - 9.10 RECENT UPDATES AND TRENDS IN AESTHETIC REGENERATIVE MEDICINE & SURGERY

Chair: MARINI Leonardo, TSAI Ren-Yeu • What's new in energy-based devices MARINI Leonardo, Italy • What's new in injectables PENG Peter Hsien-Li, Taiwan

9.10 - 9.25 STAROPENING CEREMONY

9.25 - 10.30 SHOWCASE OF INJECTABLES: UPPER FACE

Chair: VAN EIJK Tom, VOROPAI Daria • Filler contouring for foreheads of different shapes TSENG Fang-Wen, Taiwan • Importance of the hairline in forehead shaping VOROPAI Daria, UK • Periorbital rejuvenation by combining various techniques: A 'holistic' approach SHAH Falguni, India • Four dimensional rejuvenation of the lower eyelid using hyaluronic acid VAN EIJK Tom, Netherlands

11.00 - 12.00 SHOWCASE OF INJECTABLES: UPPER FACE VIDEOLIVE DEMO

Chair: SHAH Falguni, VAN EIJK Tom • Live Demo 1: Forehead RAVICHANDRAN Simon, UK • Live Demo 2: How do you treat a frown? VAN EIJK Tom, Netherlands • Live Demo 3: Peri-orbital rejuvenation with different modalities, importance of the brow VOROPAI Daria, UK in different cultures

12.00 - 13.00 SHOWCASE OF INJECTABLES: MIDFACE & NOSE

Chair: HUANG Peter Yao-Chu, ROJANAMATIN Jinda • Nasolabial fold, not just a simple fold ROJANAMATIN Jinda, Thailand • The difficult-to-correct depressions in mid-face: Mechanism and management YANG Ching-Sheng, Taiwan • Tips for midface treatments AVELAR Luiz, Brazil • Functional facial rejuvenation: A total lift solution HUANG Peter Yao-Chu, Taiwan

14.00 - 15.00 SHOWCASE OF INJECTABLES: MIDFACE & NOSE VIDEOLIVE DEMO

Chair: HUANG Peter Yao-Chu, ROJANAMATIN Jinda • Live Demo 1: Challenging cases of filler injection ROJANAMATIN Jinda, Thailand • Live Demo 2: Ligamental lifting HUANG Peter Yao-Chu, Taiwan • Live Demo 3: Nose injection in Asian patient HUANG Jeff Cheng-Chieh, Taiwan

15.00 - 16.00 SHOWCASE OF INJECTABLES: LOWER FACE & NECK

Chair: HUANG Allen Yao-Lin, ZABNENKOVA Olga • Improvement of perioral aesthetics with orthognathic surgery CHEN Peter Ruei-Feng, Taiwan • The posiblities of facial changes from orthodontic treatment CHEN Leslie Yen-Peng, Taiwan • Non-surgical approach to treating orthognathic cases with filler HUANG Allen Yao-Lin, Taiwan • Overview of different techniques & how to choose a filler for each technique VOROPAI Daria, UK • Precise jawline for young and mature patients ZABNENKOVA Olga, Russia

16.30 - 18.00 SHOWCASE OF INJECTABLES: LOWER FACE & NECK VIDEOLIVE DEMO

Chair: HUANG Allen Yao-Lin, PIRAYESH Ali • Horizontal neck wrinkles - An effective & durable solution TSENG Fang-Wen, Taiwan • Strategies of aging sign correction of the neck with a PCL-based dermal filler LIN Shang-Li, Taiwan • Live Demo 1 HUANG Allen Yao-Lin, Taiwan • Live Demo 2: SAMIZADEH Souphiyeh, UK • Live Demo 3 PIRAYESH Ali, Netherlands Sunday 12 MAY

ROOM 201EF Level 2

9.30 - 10.30 EMERGING ENERGY-BASED DEVICES: PICOSECOND LASERS - WHERE ARE WE NOW

Chair: LEE Mei-Ching, MANUSKIATTI Woraphong • Pico toning: A game changer in facial rejuvenations MANUSKIATTI Woraphong, Thailand • The role of picosecond laser in melasma treatment LEE Mei-Ching, Taiwan • Is fractional focused picosecond laser necessary for melasma treatment? A histological study LIN Jeng-Hsien, Taiwan • Combined picosecond 532/1064nm and Q-Switched 694nm laser in Asians PENG Peter Hsien-Li, Taiwan

11.00 - 13.00 EMERGING ENERGY-BASED DEVICES

Chair: CALDERHEAD R. Glen, MANUSKIATTI Woraphong • My pearls in rejuvenation treatment by using EBD-define the limits and potential MIYATA Nariaki, Japan • Neck rejuvenation using a fractional radiofrequency device MANUSKIATTI Woraphong, Thailand • Combined fractional microneedling radiofrequency and thulium laser treatment offers synergistic CALDERHEAD R Glen, South Korea skin rejuvenation • Microneedle radiofrequency for difficult conditions: Striae distensae, hyperhidrosis and CALDERHEAD R Glen, South Korea hidradenitis suppurativa • Intradermal delivery of injectable PLLA with microneedle RF for acne scar SEO Suk Bae, South Korea • Gradationally approched strategy for various enlarged or clogged pore treatment based on EBD LEE Geun Soo, South Korea

14.00 - 16.00 UPDATES IN VASCULAR TREATMENT

Chair: MARINI Leonardo, YANG Jason Chih-Hsun • An overview of laser for vascular anomalies BEKHOR Philip, Australia • Resistant PWS: new treatment approach MARINI Leonardo, Italy • Clinical study on laser treatment of hemangioma and PWS ZHOU Guoyu, China • Varicose vein management: Minimally invasive treatments vs surgery WONG Sky Tin-Hau, Hong Kong • Sclerotherapy for leg varicose veins CHANG David Yao-Yu, Taiwan • Thermal and non-thermal ablation in varicose vein treatment CHANG Shyue-Luen, Taiwan • Complications in varicose vein treatment CHANG Shyue-Luen, Taiwan

16.30 - 18.00 SCAR FORUM

Chair: MANUSKIATTI Woraphong, HSU Chao-Kai • Combination treatments for acne scars MARINI Leonardo, Italy • Fractional picosecond laser for treatment of atrophic acne scar MANUSKIATTI Woraphong, Thailand • Keloids, hypertrophic and atrophic scars: What’s new in treatment technologies ZABNENKOVA Olga, Russia • Adipose mesenchymal stem cell for wound healing of facial scar KENCANAWATI Anne Carolina, Indonesia • Non-surgical improvement of cleft lip scars: Cut-fill-strengthen-isolate VAN EIJK Tom, Netherlands • Maximizing efficacy of energy based devices in the treatment of atrophic acne scar CHENG Carl Kuo-Liang, Taiwan • Scar Wars: Keloid surgery NG Chau-Yee, Taiwan Sunday 12 MAY

ROOM 102 Level 1

11.00 - 13.00 ULTIMATE FEMININE REJUVENATION

Chair: CHEN Pao-Jen, LEYLEK Ozgur • Strategy of postpartum tightening: From energy decice to injection CHEN Pao-Jen, Taiwan • Radiofrequency and combined therapy for intimacy improvement CHEN Pao-Jen, Taiwan • Intravaginal thread procedures for rejuvenation, tightening (VTT-L / VTT-C) and stress urinary LEYLEK Ozgur, Turkey incontinence (PuTL) • Functional value of perineal body in female sexuality INTROITAL TONGUE ® LEYLEK Ozgur, Turkey • Designer Barbie vagina: How to achieve better results DECANGCHON Francis, Philippines • Non-ablative Erbium laser treatment for female SUI NOVAKOV Aleksandra, Serbia • Feminine rejuvenation and safety of energy based devices NOVAKOV Aleksandra, Serbia & VIZINTIN Zdenko, Slovenia

14.00 - 16.00 BODY CONTOURING: CURRENT & FUTURE TRENDS

Chair: LIM Ting Song, DECANGCHON Francis • Ice-fire for better body contouring LIM Ting Song, Malaysia • Clinical benefit of using a multifractional Er:YAG laser combined with a 15% TCA plus AHAs for the STANKOVIC Nenad, Serbia treatment of striae distensae • Efficacy in the treatment of edematous-fibroesclerotic paniculopathy with recombinant enzymes MENDEZ ESPANA Mauricio, USA by PBSerum • Advanced photo-thermal laser layering techniques and low concentration TCA peels tissue MARINI Leonardo, Italy priming before HA injection for stretchmarks • A 3D approach to submental fat with deoxycholate injection CHENG Charles, Canada • Facial and submental Lipolyss therapies using Alpha 1-Glycerophosphocholine (GPC) DECANGCHON Francis, Philippines

16.30 - 17.30 PITFALLS TO AVOID IN AESTHETIC PROCEDURES

Chair: PENG Peter Hsien-Li, WANG Shiou-Han • Pitfalls to avoid in the treatment of energy based devices WANG Shiou-Han, Taiwan • Retrobulbar hyaluronidase injection to the rescue, maybe not: An in vitro model assessing the CHENG Charles, Canada penetration of hyaluronidase through optic nerve dura for management of hyaluronic acid facial filler embolism • How to prevent bizzare filler face-principle and strategy PENG Peter Hsien-Li, Taiwan • Management of dermal filler complications: Common and severe adverse events LI Chien-Nien, Taiwan Sunday 12 MAY

ROOM 101A Level 1

11.00 - 12.30 TOP CLINICAL CASES: INTERACTIVE DISCUSSION

Chair: LIN Chrang-Shi Moderator: MARINI Leonardo Top Clinical Cases are pertinent to one of the following categories: • Pigmentary disorders LEE Geun-Soo, Korea • Vascular disorders ZHOU Guoyu, China • Skin inflammatory and neoplastic disorders CHAO Sheau-Chiou, Taiwan • Injectables WANITPAKDEEDECHA Rungsima, Thailand • Injectables LIM Ting Song, Malaysia

12.30 - 13.00 RISING STARS FORUM

Chair: TSAI Tsen-Fang • Best practice for publishing a scholarly article MARTIN Druanne, USA • Vitiligo treatment: Is there more that we can do? NG Chau-Yee, Taiwan

14.00 - 16.00 REGENERATIVE MEDICINE AND MICROBIOME: CELL THERAPIES & MICROBIOME

Chair: LIU Hen-Yu, KONTUREK Peter C. • Overview of cell therapy and regenerative medicine LIU Hen-Yu, Taiwan • The application of cell therapy in dermatology CHEN Chih-Chiang, Taiwan • Cell therapies in aesthetic medicine, surgery and anti-aging LIU Hen-Yu, Taiwan • Regenerative cell therapy in aesthetic medicine and surgery PIRAYESH Ali, Netherlands • Impact of mesenchymal stem cells derived culture medium in skin cells aging: An approach to use PATHAK Surajit, India laboratory research in clinics for skin cell rejuvenation • Skin and gut microbiota interactions relevant for aesthetics medicine D’ALESSIO Patrizia, France • Fecal Microbiota Transfer 2019: What's next? KONTUREK Peter C., Germany • From stem cells to tissue engineering: reality versus theory GRAZIANO Antonio, Italy

16.30 - 17.30 FOCUS SESSION ON NOSE BEAUTIFICATION

Chair: RAVICHANDRAN Simon, CHIU Yu-Hsun • Anatomy of the nose: A technique to achieve safe and effective outcomes from non surgical RAVICHANDRAN Simon, UK rhinoplasty procedures • Short nose with upward tip projection: How do I manage it? HUANG Jeff Chen-Chieh, Taiwan • Boundary between non-surgical & surgical nasal augmentation (I) CHIU Yu-Hsun, Taiwan • Boundary between non-surgical & surgical nasal augmentation (II) CHIU Yu-Hsun, Taiwan

17.30 - 18.00 PRACTICE MARKETING

• 9 ways to market your medical practice with social media: A doctor's guide STANKOVIC Nenad, Serbia • Digital as a powerful marketing tool for doctors and clinics ASHOUR Mahran, United Arabs Emirates Sunday 12 MAY

ROOM 201ABC Level 2

8.30 - 10.30 UPDATES IN MOLECULAR DIAGNOSIS & NON-INVASIVE SKIN DIAGNOSTIC TOOLS

Moderator: WANG Jen-Yu, WU Nan-Lin • Application of ultrasound in dermatology WANG Jen-Yu, Taiwan • Evaluation of venous insufficiency and essential of venous ultrasound CHANG Shyue-Luen, Taiwan • Application of molecular tools in clinical mycology SUN Pei-Lun, Taiwan

11.00 - 13.00 PHOTOMEDICINE

Moderator: LAN Eric Cheng-Che, SHEU Hamm-Ming • Long term UVB phototherapy and skin cancer risk CHEN Yi-Ju, Taiwan • Photochemistry in the service of dermatology LAI Feng-Jie, Taiwan • The evidences and benefits of laser treatment for melasma HUANG Ching-Hsin, Taiwan

14.00 - 16.00 ATOPIC DERMATITIS

Moderator: CHU Chia-Yu, WANG Wei-Ming • Asian atopic dermatitis VS. European atopic dermatitis CHAN Tom, Taiwan • Managing atopic dermatitis: Differences between adults and children LIN Yi-Ting, Taiwan • Holistic management of atopic dermatitis: Firsthand experience from a dermatologist with YU Peter, Taiwan atopic dermatitis • Update on systemic therapies for managing moderate to severe atopic dermatitis YANG Chin-Yi, Taiwan • Emerging biologics in atopic dermatitis CHO Yung-Tsu, Taiwan • Atopic dermatitis guideline update CHU Chia-Yu, Taiwan

16.30 - 18.00 PEDIATRIC DERMATOLOGY

Moderator: SHIH I-Hsin • Treatment of infantile hemangioma BEKHOR Philip, Australia • Current systemic therapies for pediatric atopic dermatitis HUI Rosaline Chung-Yee • Pediatric dermatology in Brief: From A to Z YU Peter, Taiwan Sunday 12 MAY

Sessions in Mandarin ROOM 103 Level 1

8.30 - 9.30 INTERFACE BETWEEN RHEUMATOLOGY AND DERMATOLOGY (Mandarin)

Moderator: HUANG Yu-Huei, LI Ko-Jen • Scleroderma update LI Ko-Jen, Taiwan • Derma lupus overlaps KUO Hsiao-Ling, Taiwan

9.30 - 10.30 WHEN AND HOW TO USE BIOLOGIC AND SMALL MOLECULE THERAPIES (Mandarin)

Moderator: HUANG Yu-Huei, LI Ko-Jen • Selecting ideal biologic treatment for psoriasis: which therapy for which patient CHIU Hsien-Yi, Taiwan • Emerging therapy-small molecule drug in dermatology LAI Po-Ju, Taiwan

11.00 - 12.00 URTICARIA AND PRURITUS (Mandarin)

Moderator: CHEN Chih-Chiang • The pathogenesis of pruritus WENG Hao-Jui, Taiwan • Infinite itch in chronic urticaria: progress toward pathogenesis and treatment LIN Yi-Ting, Taiwan • What’s new in chronic urticaria? CHO Yung-Tsu, Taiwan • Biologic treatment for urticaria and pruritus CHEN Yi-Hsing, Taiwan

12.00 - 13.00 VITILIGO (Mandarin)

Moderator: LIN Tzu-Kai • The surgical treatment of vitiligo BEHROOZ Kasraee, Switzerland • Autologous regenerative therapies in segmental vitiligo retrospect and prospect KAO Chao-Hsing, Taiwan

14.00 - 15.00 FROM BENCH TO BEDSIDE (Mandarin)

Moderator: HUANG Patrick Po-Han • Why dermatologists should do basic research? CHU Chia-Yu, Taiwan • Application of whole genome sequencing in clinical practices CHUNG Wen-Hung, Taiwan • The role of mechanical force in the pathogenesis and treatment of keloid HSU Chao-Kai, Taiwan • Fungal barcoding: The role of molecular Identification of fungal pathogens in clinical practice SUN Pei-Lun, Taiwan • New strategy for hair regeneration CHEN Chih-Chiang, Taiwan

15.00 - 16.00 NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (Mandarin)

Moderator: HUANG Patrick Po-Han • Why minimal toxin dosing? HUANG Patrick Po-Han, Taiwan • How to predict the importance of demodex in patients with rosacea? HUANG Hui-Peng, Taiwan • How I use low dose propranolol in kids with hemangioma DAI Yang-Shia, Taiwan • Why I don’t do Nd YAG laser sweeping TSAI Ren-Yu, Taiwan • Microbiome in dermatology: Now and the future CHEN Yi-Ju, Taiwan • Diagnostic clue to genodermatoses CHAO Sheau-Chiou, Taiwan

16.30 - 18.00 SKIN INFECTION AND SEXUALLY TRANSMITTED DISEASES (Mandarin)

Moderator: HO Ji-Chen • Updates in the skin mycology SUN Pei-Lun, Taiwan • Latent TB prophylaxis WANG Jann-Yuan, Taiwan • HPV vaccination program WEI Lin-Hung, Taiwan • Cutaneous protothecosis TSENG Han-Chi, Taiwan • Skin mycobacterial infections TSENG Yu-Ju, Taiwan • Re-emerging syphilis: An old but close friend TING Sze-Wen, Taiwan Workshops SATURDAY 11 MAY

ROOM 201D Level 2

10.00 - 13.00 MERZ

• Welcoming remark and introduction of speakers WU Ying-Chin, Taiwan • Global consensus guidelines for the injection of diluted CaHA for skin tightening GOLDIE Kate, UK • Full face considerations for incobotulinumtoxin-A injection HO Wilson, Taiwan • Bold lift: Injection strategy for whole-face rejuvenation HUANG Yung Hsueh, Taiwan • “Don’t Treat Blindly - See, Plan and Treat” GOLDIE Kate, UK • A single-visit approach using fillers and incobotulinumtoxin A: full face enhancement in CHAO Yates Yen-Yu, Taiwan Asian patients

13.00 - 15.00 LUNCHEON SYMPOSIUM: ALLERGAN

Moderator: PENG Peter Hsien-Li • VOLITE®: An Innovative Injectable Treatment for Improving Skin Quality LAU Katie, Hong Kong • BOTOX® and Juvederm®: The Math and Myth of Combination Treatment LU Victoria Ching-I, Taiwan • Live Demo LU Victoria Ching-I, Taiwan

15.00 - 16.00 CLOVERS MEDTECH

Moderator: HU Sindy • Strategies of stepwise 2ml volume restoration for aging sign correction with Ellansé LIN Shang-Li, Taiwan • The inside art of silhouette instalift LAM Phoebe Kar Wai, Hong Kong

16.30 - 17.30 ULTRA V

• Forehead lifting and glabellar wrinkle treatment with Octotwist PDO & PCL KWON Han-Jin, South Korea • New A type cannula with less pain & easy insertion for threads KWON Han-Jin, South Korea • Non-surgical eyebag removal: Cannula, Supertornado, Inch & PDO Powder Filler KWON Han-Jin, South Korea Workshops SATURDAY 11 MAY

ROOM 102 Level 1

14.00 - 17.30 GALDERMA

Moderator: AVELAR Luiz, CHAO Yates Yen-Yu • Aesthetic outcomes of botulinum toxins, a real world practice LI Chien-Nien, Taiwan • Lower face, higher standard with Galderma portfolio AVELAR Luiz, Brazil • Live Demonstration AVELAR Luiz, Brazil • Achieve dynamic facial harmony with NASHA, OBT HA and PLLA CHAO Yates Yen-Yu, Taiwan • Live Demonstration CHAO Yates Yen-Yu, Taiwan • Closing of the session All Faculty

NORTH LOUNGE Level 2

9.30 - 10.30 CANDELA: TOTAL TREATMENT SOLUTION FOR SKIN REJUVENATION

Moderator: LIAO Yi-Hua • Opening LIAO Yi-Hua, Taiwan • Novel application of ultrashort pulse picolaser assisted drug delivery in melasma and other CHENG Kuo-Liang, Taiwan pigmented lesions treatment • Fractional RF mirconeedling device for treating body skin laxity and cellulite PENG Peter Hsien-Li, Taiwan • Combined laser and IPL to optimize clinical outcomes for Port Wine stain BEKHOR Philip, Australia • Q&A • Closing of the session LIAO Yi-Hua, Taiwan

11.00 - 11.30 SESDERMA

• The new edge therapy in the melasma & skin rejuvenation SERRANO Gabriel, Spain

11.30 - 12.00 SCIENTIS

Moderator: LIM Joyce • The clinically proven superior benefits / risks balance of cysteamine compared to Kligman's MARINI Leonardo, Italy formula

13.00 - 14.00 LUNCHEON SYMPOSIUM: MYGUARD

Moderator: LIN Chrang-Shi • Facial appearance: Capturing the rejuvenation effects of treatments in BEFORE-and-AFTER ARKESTEIJN Walter, Netherlands pictures with the OBSERV® • The use of OBSERV® to evaluate melasma HSU Che-Hao, Taiwan • Clinical application of OBSERV® to reveal subtle facial treatment effects LIU Li-Lin, Taiwan

14.00 - 15.00 FOTONA: TREATMENT OF PIGMENTATIONS USING STARWALKER AND FRACTAT

• New approach to the laser treatment of pigmentations and tattoos VIZINTIN Zdenko, Slovenia • Live Demo: The use of StarWalker laser system in treatment of pigmentation and/or tattoo MARINI Leonardo, Italy

15.00 - 15.30 ALMA

Moderator: CHANG Wei-Ting • Pixel CO2 for wide range of aesthetic applications ISRAELI Hadar, Israel Workshops SUNDAY 12 MAY

ROOM 201D Level 2

9.30 - 10.00 TBMS

Moderator: HU Sindy • Noninvasive laser-assisted curvature contouring with 1060 nm laser lipolysis SculpSure: A new CHENG Kuo-Liang, Taiwan paradigm for making perfect body curve

10.00 - 10.30 SOLTA

Moderator: TSENG Chung-Jen • The latest advancements: Expert’s experience for non-invasive tightening device Thermage FLX KING Walter W.K., Hong Kong

11.00 - 12.00 UGINTECH

Moderator: TSAI Ren-Yeu • Safety and efficacy of 6 mm high intensity focused ultrasound (Ultraformer III) for non-invasive HSU Nai-Jen, Taiwan reduction of submental fat • Improvement of periorbital wrinkles treatment with 2 mm high intensity focused ultrasound TSENG Jonathan Te-Peng, Taiwan (Ultraformer III)

12.00 - 12.30 ULTHERA

Moderator: HSU Nai-Jen • Lower face skin tightening and lifting using MFU-V with a nape lifting protocol LIN Shang-Li, Taiwan

12.30 - 13.00 COLLAMATRIX

Moderator: PENG Yu-Pin • Clinical experience with picosecond 595 nm laser and HEXA fractional handpiece HWANG Chian-Yaw, Taiwan

13.00 - 13.30 LUNCHEON SYMPOSIUM: COLLAMATRIX

Moderator: PENG Yu-Pin • Alternative applications in picosecond-laser scar treatment: Mini spot-sized MLA and stacking LI Chien-Nien, Taiwan technique

13.30 - 14.00 LUNCHEON SYMPOSIUM: PICOWAY

Moderator: PENG Peter Hsien-Li • Dawn of a new era -new concept and handpiece of triple wavelength picosecond laser for full face MIYATA Nariaki, Japan treatment

14.00 - 15.00 QUANTA SYSTEM

Moderator: PENG Peter Hsien-Li • Picosecond lasers and 585nm fractional yellow laser: what's new? LIN Jeng-Hsien, Taiwan • Treating Asian pigmentations: My Recipe CHUANG Celina Ying-Yen, Taiwan • Distinguishing features of DISCOVERY PICO laser CHANG Hung-Chia, Taiwan

15.00 - 16.00 LUMENIS

• Treatment of acne scars in Asians using UltraPulse Fractional CO2 Laser CHENG Kuo-Liang, Taiwan • Exceptional performance of UltraPulse in the treatment of skin texture and acne scar LIN Shang-Li, Taiwan • Laser skin resurfacing treatment outcome of acne scars, scars and wrinkles in Asians with PENG Peter Hsien-Li, Taiwan UltraPulse CO2 laser Workshops SUNDAY 12 MAY

ROOM 102 Level 1

9.30 - 11.00 GALDERMA

Moderator: HUANG Hui-Peng, LIN Chrang-Shi • The role of the dermatologist in ocular demodicosis: A clinical challenge HUANG Hui-Peng, Taiwan • Association of demodicosis with oily skin: Clinical observation and experience sharing CHUANG Celina Ying-Yen, Taiwan • Common errors and misconceptions in skin care for rosacea CHIU Pin-Chi, Taiwan

NORTH LOUNGE Level 2

11.30 - 12.00 SUNMAX

• Collagen filler for the correction of tear through and dark circles: Their clinical outcomes SHI Tsung-Hsien, Taiwan

12.00 - 13.00 WOH MEDICAL

Moderator: WANG Cheng-Kun • How to treat upper and lower (sunken eyes) with Princess filler LIANG Ben Chung-Pin, Taiwan • Croma Pharma: A family owned company that treats you as family BERMAN Dror Dean, Austria

13.00 - 14.00 LUNCHEON SYMPOSIUM: MEDYTOX

Moderator: HSU Nai-Jen • Body toxin and safe advanced injection skill PARK Young-Woon, Korea

14.00 - 15.00 RENAISSE

Moderator: TSAI Ren-Yeu • An innovative regenerative treatment: Dermis micro-grafting in the management of androgenetic GRAZIANO Antonio, Italy alopecia • Regenerative treatment of androgenetic alopecia with micrografts: clinical experience with TSENG Jonathan Te-Peng, Taiwan Taiwanese patients POST-CONGRESS Course Monday 13 MAY 8.30 - 18.00 HANDS-ON ANATOMY WORKSHOP: PRACTICAL ANATOMY FOR INJECTABLES & THREAD LIFTS National Taiwan University Hospital - Minimally Invasive Surgery Training Center B1F, No. 2, Xuzhou Road Zhongzheng District 100, Taipei City (The center is located at B1F of NTUH International Convention Center)

COURSE DIRECTORS

Dr. LIAO Yi-Hua Dr. HSU Nai-Jen Dr. WANG Chao-Chin

ORGANIZING COMMITTEE ¥¥Dr. LIAO Yi-Hua ¥¥Dr. HSU Nai-Jen ¥¥Dr. KO Jenq-Yuh ¥¥Dr. WANG Chao-Chin ¥¥Dr. YANG Ting-Hua

Overview

This full-day hands-on anatomy workshop is dedicated to medical doctors who wish to master the practical anatomy for minimally invasive aesthetic procedures, including injectables and thread lifts.

The course begins with lectures covering the vital anatomy structures for aesthetic procedures. World-class faculties will deliver different perspectives of anatomist and clinicians. Pearls for safe injection by anatomical zones and different thread-lifts system will be discussed.

Attendees will have ultimate, risk-free, hands-on experience in this workshop. They will perform injection of filers on 3D simulation model which automatically identifies the correct plane of injection. They will also practice fillers injection and thread insertion on cadaver head, followed by live dissection to reveal the true result of practice.

Optimal anatomical plane of treatment remains the fundament to safe and successful minimally invasive aesthetic procedures. By taking part in this course, attendees will be able to practice and refine their technique in these procedures with the guidance of experts. Speakers Short Biographies SPEAKERS

ARKESTEIJN Walter, Walter Arkesteijn is a Dutch entrepreneur CHANG David Yao-Yu , Dr. Yao-yu Chang is a board-certified and inventor. With a background in electronics engineering, he is the Taiwanese dermatologist. After residency, he went on to Johns founder and CTO of the Netherlands-based company InnoFaith Hopkins Dermatology in the United States for training in Mohs beauty sciences where his passion for skin, biosciences and surgery, cutaneous oncology, as well as cosmetic surgery. Now he engineering converge. With a profound knowledge of human skin and serves as a faculty member in Chang Gung Memorial Hospital hair biology and an award-winning skin analysis device under his Dermatology, and specializes in Mohs micrographic surgery and name, Walter Arkesteijn is a widely recognized pioneer bringing varicose vein treatment. He has also been invited to lecture in many innovation to the cosmetic industry. domestic and international meetings.

ASHOUR Mahran, With a rich background in the operational and CHANG Chi-Hao , Doctor Chih-Hao Chang is a surgical business aspects of healthcare operations; Mahran is a leading dermatologist of Chang Gung Memorial Hospital, Keelung branch. He business consultant in the Gulf and Middle East and North Africa completed his residency and fellowship in the Department of (MENA). He launched the first 5-star clinic in the region: Glamour Dermatology in Chang Gung Memorial Hospital. He is interested in Care Clinics, and as the founder of M.A Healthcare Consultancy, he the field of surgical dermatology, particularly oncology, phlebology, is sought by healthcare businesses across MENA to achieve and onychology. He would like to share his experience about business expansion. He is a world-wide speaker on business conservative treatment of paronychia in nail brace workshop. management in the medical and aesthetics field.

AVELAR Luiz , Graduated in 1989, Board Certified Plastic CHAO Yates Yen-Yu , Yates, well-known as an expert in Surgeon, full member of the Brazilian Society of PS and ASPS. aesthetic dermatology, is an active lecturer/trainer across the world Forensic Anthropologist from the Police Department of the State of and keynote speaker in major international conferences. During over Minas Gerais, Dr. Avelar studies the “PHYSIOPATHOLOGY OF 20 years of practice, he innovated and published many novel FACIAL AGING”, analyzing the bone remodelation on more than 500 techniques. His works and talks are apparently full of artistry. CHAO skulls. Author of the book “ATLAS DE MEDICINA LEGAL” and has Institute of Aesthetic Medicine in Taipei trains global doctors. He is many publications at PLASTIC AND RECONSTRUTIVE SURGERY now on advisory boards of the leading brands of lasers, devices, and JOURNAL OF DRUGS IN DERMATOLOGY about this subject. fillers, toxins and skin care products.

AVERINA Vladlena , MD, is certified specialist in CHAO Sheau-Chiou , Education 1985-1990 M.D. College of dermatovenereology & aesthetic medicine since 1998, from Kiev Medicine, National Cheng Kung University Career 1990-1994 Medical University (Ukraine). Works at Kiev Hospital “Zdravitsa”. Has Resident, Department of Dermatology, National Cheng Kung extensive experience with different fillers, BoNT-A, PRP, University Hospital 1999-2000 Researcher, Department of mesotherapy, peelings, threads. She writes over 40 scientific articles Dermatology, Thomas-Jefferson University 2002- Associate for aesthetic dermatology journals. She is EADV member. Dr.Averina Professor, Department of Dermatology, College of Medicine, National is President of Association of Aesthetic Gynecology and Andrology Cheng Kung University 2015- Chief, Department of Dermatology, College of Medicine, National Cheng Kung University

BANERJEE Antara , Dr. Antara Banerjee is an Indian born CHAUCHARD Claude, obtained his doctorate in Endocrinology, Scientist and and Assistant Professor at Chettinad Academy of Biology and Sports Medicine from the University of Montpelier, Research and Education, India. She received her Ph.D from India in France. Chairman of the Asia Pacific Academy of Anti-Aging 2008 with 10 years of work experience from Italy, Sweden. Her medicine, and former Assistant Professor at the University of research focuses on Cancer biology, Regenerative medicine / Stem Montpellier (1974-1979), he is one of the world’s top Specialists in cell based therapies for Inflammatory Bowel disease/ Colon cancer. preventive medicine for aging. Over one million copies of his thirteen She has over 45 peer reviewed publications and research grants to books on ageing process have been sold. work on stromal cells and tumor microenvironment.

BEKHOR Philip , Specialist in procedural dermatology involving CHEN Chih-Chiang , Dr. Chih-Chiang Chen got his M.D. and the laser and surgical management of skin disorders including Ph.D. degree from National Yang Ming University, Taiwan. After cosmetic dermatology and specialist in Mohs Micrographic surgery. finishing his residence training from the Department of Dermatology, His interests also focus on newly evolving safe and effective cosmetic Taipei Veterans General Hospital, he applied to be a visiting scholar procedures with minimal downtime, such as superficial skin peels, fat at the Department of Pathology, University of Southern California for transfer, injections of natural and synthetic "fillers", and wrinkle proceeding his basic research. What he focuses is on how reducing muscle relaxants. extra-niche macro-environment regulates the homeostasis of stem cells.

BERMAN Dror Dean , Dr Dror Dean Berman is an aesthetic CHEN Peter Ruei-Feng , EDUCATION 1. M.D.Taipei Medical doctor, that has been practicing and teaching the art, anatomy, University, Taipei, 1994-2000 2. Fellowship under Prof Chien Tzung physiology of aesthetic medicine to nurses and doctors for years in Chen M.D: Department of trauma plastic Surgery, Chang Gung Tel Aviv. After working as the head trainer of EMEA for Merz as well Memorial Hospital, Linko, Taiwan, 2006-2007 3. Fellowship under with KOL , Dr Berman was chosen to become the Chief Medical Prof Yu Ray Chen M.D: Department of Craniofacial plastic Surgery, Officer at Croma Pharma GmbH, a family owned Pharma company in Chang Gung Memorial Hospital, Taiwan, 2007-2008 Dr. Chen is the Austria, which develop dramatically to become one of the leading author and co-author of several research publications on aesthetic aesthetics companies in the market. surgery. He also attends international congresses worldwide.

CALDERHEAD R. Glen, R. Glen Calderhead, PhD, DrMedSci, CHEN Jau-Shiuh , Jau-Shiuh Chen is a visiting staff of FRSM, is Director of Research at Clinique L Dermatology, Goyang. Department of Dermatology, National Taiwan University Hospital. He South Korea. He is an eminent expert in the field of light and received the M.D. degree from National Taiwan University College of energy-based science, from lasers,through IPLs, LED devices & RF . Medicine. He is interested in the fields of laser medicine and skin He is Secretary-General, World Anti-ageing Medical Association and surgery. He is currently the director of the Laser and Photonics an Honourary Member of the ESLAS. Dr Calderhead is lead author Medicine Society of the Republic of China, and the director of the on a number of key publications on photosurgery, phototherapy and Taiwan Society for Dermatological and Aesthetic Surgery. related treatment modalities.

CHAN Tom, Dr. Tom C. Chan is a board-certified dermatologist in CHEN Yi-Ju, Dr. Yi-Ju Chen is currently the Director, Department Taiwan. His clinical interests are inflammatory skin diseases, of Dermatology, at Taichung Veterans General Hospital. Her research including psoriasis, atopic dermatitis, and hidradenitis suppurativa. interest focuses on the comorbidities and management of several With a post-doctoral training in the Lab for Investigative Dermatology chronic inflammatory diseases including psoriasis, rosacea and atopic at The Rockefeller University, he focuses on the translational dermatitis. Dr. Chen also investigate the link between cutaneous and analyses of these inflammatory skin diseases. gut microbiota and the pathogenesis of these complex diseases.

CHANG Ying-Jui , Dr. Ying-Jui Chang is the director of Dr. CHEN Pao-Jen , Dr. Pao-Jen Chen received full training in Deung's Skin Clinic at New Taipei City, Taiwan. Prior to opening his obstetrics and gynecology, and also participated in aesthetic surgery clinic, he has served as Director of Dermatology and Medical and related business for more than 15 years. In 2018, he served as Aesthetic Center at Far Eastern Memorial Hospital. Dr. Chang Chairman of Taiwan Association of Psychosomatic Obstetrics and completed his residency at Mackay Memorial Hospital, and then Gynecology. He is responsible for the improvement of women's received Dermatologic Surgery fellowship at Toranomon Hospital, physical, psychological, and sexology issues. He is also the Japan. Dr. Chang is interesting in Dermatologic Surgery, Laser counselor of the Taipei City Government of Taiwan on mental health. surgery, toxins/fillers injections, and Dermoscopy.

CHANG Shyue-Luen , Current Appointment Vice Chief: CHEN Kai-Lung, Dr. Kai-Lung Chen is a certified dermatologist in Department of Dermatology and Cosmetic Center, Chang Gung Taiwan. He received his dermatology training in National Taiwan Memorial Hospital, Taoyuan, Taiwan Assistant Professor: Department University Hospital and had been performing clinical care in the past of Dermatology, Chang Gung University, Taiwan Leading physician: two years as an attending physician at NTUH, Hsin-Chu branch. Dr. Vein Clinic, Chang Gung Memorial Hospital, Taipei/Taoyuan, Taiwan Chen’s personal interests and investigations include general Experiences Research fellow, M.D. Anderson Cancer Center, dermatology and cancer therapy related skin toxicities. Currently he is Houston, TX. U.S.A Fellow, Morrison Vein Institute, Phoenix, AZ. a consultant dermatologist at NTU Cancer Center. U.S.A Member of review committee in Taiwan FDA for varicose vein CHEN Yi-Chin, Dr Yi-Chin Chen is a board-certified dermatologist CHUANG Celina Ying-Yen , Dr. Celina Chuang is a young in Taiwan. After finishing her dermatology residency, she went to board certified dermatologist practicing in New Taipei City, Taiwan. Yonsei University, Severance Hospital in Seoul for further study of Since completing her residency, she has continued to expand her Mohs surgery. In addition, she went to CHU Brugmann UVC knowledge, focusing her practice in the fields of acne, acne scar, and (Brugmann University Hospital) in Bruxelles for learning more nail scar treatment. Acne scar evaluation and its treatment are important surgery and nail diseases every year. She had special nail part of her private practice. She lectures regularly nationally and consultation clinic and focused on nail diseases, nail brace and nail internationally both to her peers and to the public on the latest in surgery. energy-based devices.

CHEN Leslie Yen-Peng , National certificated-specialty CHUNG Wen-Hung , Dr. Chung is a physician of dermatology Academic committee| Taiwan Association of Orthodontists Best case and a specialist of the field in severe cutaneous adverse drug award| Taiwan Association of Orthodontist Lecturer of international reactions and cutaneous immunologic disorders. He currently serves advanced course | School of Dentistry, National Taiwan University as director of department of dermatology and drug hypersensitivity Master in orthodontics| National Taiwan University Certificated clinical and research center at Chang Gung Memorial Hospital. Dr. member| Japanese Society of Esthetic Dentistry Chung has devoted himself into the investigation of severe adverse drug reactions (SCARs) for over a decade and his devotion and findings have great impact in clinic.

CHENG Charles, With over 26 yrs of experience in non-surgical CHUNG Kee Yang , Dr. Kee-Yang Chung is a Professor of aesthetics, Dr. Cheng started with chemical peels in 1992, Botox in Dermatology at Yonsei University College of Medicine in Seoul, 1993 and Restylane in 1998. With the large East Asian population in Korea. He specializes in Mohs micrographic surgery and Vancouver, Canada, Dr. Cheng is a leading Canadian expert in reconstruction for skin cancers, autologous fat AFT and keloid injectables. He is a clinical assistant professor at the University of surgery. He is an active member of ASDS (ITMP mentor ), DASIL British Columbia, Medical Council of Canada licensing examiner, and (board member), and a board member for the Asian Dermatological a clinical consultant for the medical aesthetic industry in research and Association. He is also serving as the president of the Korean Society physician training. for Aesthetic and Dermatologic Surgery.

CHENG Carl Kuo-Liang , Dr Carl Cheng is a board certified D'ALESSIO Patrizia , Pr. Dr. Patrizia d’ALESSIO, MDPhD dermatologist in Taiwan. He is especially interested in energy baded international expert biological mechanisms of inflammaging and devices and injectables. He is also a speaker or advisory board for stress. Medicine & Hematology Milan, PhD Utrecht. Cell Biology Paris Cynosure, Syneron candela , Merz, Q med, Allergan, etc 5 and 11 Universities. Bio-guided research anti-inflammatory actives. 2005 French Innovation Award. Founder R&D start-up AISA Therapeutics. Patents granted EU, US, CN. 2009 European FP7 Ristomed project. 2015 AISA Moleculum® trademark dietary supplement. New book “L'inflammation” Dangles launching April 2019. CHI Ching-Chi , Professor Ching-Chi CHI is Professor of DAI Yang-Shia , Education: M.D. , National Taiwan University Dermatology at Chang Gung Memorial Hospital, Linkou. Prof Chi is (1993) M.Sci., Graduate Institute of Clinical Medicine, Medical passionate about the application of evidence-based medicine and College, National Taiwan University (2005) Medical Training: development of clinical practice guidelines. He is an Editor of the Resident, Pediatric Dept., NTUH Resident, Dermatology Dept., NTUH Cochrane Skin Group and an Associate Editor for Evidence-Based Clinical researcher, Dermatology Dept., Harvard Medical College Dermatology, British Journal of Dermatology. He has authored 11 Clinical researcher, Dermatology Dept., Boston Children's Hospital Cochrane reviews and coauthored two pan-European Dermatology Guidelines.

CHI Min-Hui, Dr. Min-Hui Chi is a board-certificated dermatologist DECANGCHON Francis, Aesthetic Surgeon Manila Philippines in Taiwan. She accomplished her training at the Chang Chung Specialty Lipoplasty Face/Body Contouring Autologous Fat Grafting Memorial Hospital, and currently is an attending physician and a Aesthetic Gynecologic Surgeon,World VicePres International College clinical instructor in the Department of Dermatology at Chang Gung of Surgeons,World Chairman ICS Cosmetic Aesthetic Surgery Memorial Hospital, Taipei, Keelung and LinKou branches. Dr. Chi has specialty, President ICS Metro Manila Philippine Section, President her special interests in severe cutaneous adverse drug reactions, Philippine Academy of Aesthetic Surgery, Board Chairman Philippine atopic dermatitis, and cosmetic dermatology. Academy of Aesthetic & Age Management Medicine, International Faculty/Trainer for Lipoplasty Toxins Fillers Threads

CHIU Pin-Chi, Dr. Chiu is a recognized expert on cosmeceuticals, GOLDIE Kate, Dr Goldie has been an Aesthetic Physician for 12 aesthetic dermatology, cosmetic dermatology and years and is the MD of European Medical Aesthetics Ltd. where she acne/rosacea/sensitive skin management and has conducted several has overseen the training of over 4000 medical professionals. She cosmetic clinical trials in Taiwan. He was frequently invited to speak regularly lectures globally - teaching medical aesthetics in over 40 at national and international conferences about many aesthetic and countries, with a special interest in applied anatomy. Dr Goldie has medical related topics. He also first setup the renowned cosmetic private practices in London’s Harley Street and Henley-on-Thames discussion platform by blog and Facebook group in Taiwan for public and is a member of the BCAM and the chairperson of the UK education and continued medical education. Aesthetic Medicine Expert Group.

CHIU Hsien-Yi , Hsien-Yi Chiu, MD, PhD Assistant Professor, GRAZIANO Antonio , Dentist, PhD in Biomedical Technology National Taiwan University College of Medicine Current Positions: applied in dentistry, expert in biotechnology techniques applied to 2012- Now, Attending Physician, Department of Dermatology, stem cell based tissue regeneration. Dr. Graziano is the CEO of HBW National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, and the inventor of Rigenera protocol developed in collaboration with Taiwan, ROC dr. Riccardo d’Aquino during his PhD fellowship He has a good expertise in industrial project management applied to medcare. He also author and coauthor of more of 40 scientific publications in peer review journals.

CHIU Yu-Hsun , Dr. Tony Yu-Hsun Chiu, M.D., M.M.S., is the GUEVARA Bryan , He took his residency in Dermatology at attending physician of Cosmetic Center, Department of ORL-H&N Southern Philippines Medical Center. He had visiting fellowships on Surgery at Shin Kong Wu Ho-Su Memorial Hospital, and the dermatopathology and immunodermatology in Mt. Sinai Hospital attending physician of Department of ORL-H&N Surgery at NTUH. He (New York), Hospital of the University of Pennsylvania, Yale is also certified by the board of Taiwan Academy of Facial Plastic and University Hospital & Mackay Memorial Hospital. He passed with Reconstructive Surgery. Dr. Chiu specialized in sinonasal, facial distinction the dermatopathology examination by the AADV (2018). plastic and reconstructive surgery. He is widely recognized as one of Currently, he is a fellow in dermatopathology & molecular Taiwan's leading rhinoplasty surgeons. dermatology at National Cheng Kung University Hospital, Taiwan.

CHO Yung-Tsu, As a dermatologist, my main field of interest is HO Wilson, Director of The Specialists: Lasers, Aesthetic & Plastic focused on immunologic skin diseases, including autoimmune bullous Surgery, Hong Kong and honorary assistant professor of the Faculty diseases, atopic dermatitis, urticaria, cutaneous lupus erythematosus, of Medicine, The Chinese University of Hong Kong. Authored or dermatomyositis, severe cutaneous adverse reactions, and skin co-authored over 50 articles in peer-reviewed journals and 3 book toxicities due to oncological treatments. My researches aim to further chapters, lectured extensively on injectables and light source devices, characterize the clinical presentations, to explore the minimally invasive plastic surgery & breast surgery, he is trainer for pathomechanisms, and to find better treatment modalities for these prestigious scientific institutions as well as for leading companies. diseases.

CHRISTIE Andrew R., Dr. Christie is an aesthetic specialist with HO Ji-Chen , I have worked as a dermatologist for Chang Gung 20 years’ experience. He graduated from Macquarie University & the Memorial Hospital in the past 30 years. There are two major things University Of Southampton. Having lectured as a micro-needling which I am proud to have accomplished. First is the establishment of expert in 55 countries, Andrew has been invited as a speaker at 40 the first psoriasis day care centre in Taiwan. Secondly, I pride myself major congresses. Andrew has also been a guest lecturer at 10 to have trained more than twenty young, outstanding dermatologists. universities. Andrew has appeared in hundreds of interviews as a These talented dermatologists have made major contributions to our micro-needling authority & has authored over 600 papers. Andrew society, continue to succeed in the research and clinical areas in trains over 50,000 practitioners each year. Taiwan.

CHU Chia-Yu , Dr. Chia-Yu CHU is currently the Professor of HSIAO Jack , Dr. Hsiao is the General Manager of HCC Department of Dermatology, National Taiwan University. His main Healthcare Group, a healthcare consortium in northern Taiwan. research interests include cutaneous adverse effects of drugs, atopic Graduated from Boston U. School of Medicine, a board-certified dermatitis, and immunologic dermatoses. During 2008-2010, he was specialist in obstetrics/gynecology. Dr. Hsiao was the co-coordinator a visiting professor in the University of Paris XII. As a dermatologist of Telecare Project, also held leadership positions in e-healthcare specialized in immunology and allergy, he has published more than industry, including OmniHealth Group (Boston) and 24drs.com 175 articles about drug eruption, chronic urticaria, and atopic (syndication of WebMD). A pioneer in healthcare entrepreneurship dermatitis. co-launched the first hospital-based IPO in Taiwan. HSU Nai-Jen , MD, is the director of Hsu Nai-Jen Dermatologic HUI Rosaline Chung-Yee , Dr Rosaline Hui graduated from Clinic located in Tainan, Taiwan. He is affiliated with several National Taiwan University in 1998 and received her training in professional societies including the Chinese Dermatological Society, dermatology at Chang Gung Memorial Hospital, Taipei and Linkou Laser Medicine Society of the Republic of China. He is also a certified branch. She obtained her PhD degree from Imperial College London, trainer for Restylane, Radiesse and Sculptra treatments. Dr Hsu is a UK in 2007. Presently, she is an Assistant Professor at Department of keen researcher and his work has been published in the Dermatology, Chang Gung Memorial Hospital at Taipei. Her research Dermatologica Sinica and Environmental Dermatology. interests include psoriasis, atopic dermatitis, acne, cosmetic laser and light therapy.

HSU Che-Hao , Dr.Hsu is a board certificated dermatologist and HWANG Chian-Yaw , Current Position: Superintendent, Yawen dermatologic surgeon in Taiwan. He is fully accredited in aesthetic Dermatology Clinic Experience: Attending Physician, Department of procedure such as skin rejuvenaiton, neurotoxin, filler injection, Dermatology, Wan-Fang Medical Center Attending Physician, thread lifts and lasers. Dr Hsu is the director of Hao-Skin Department of Dermatology, Taipei Veterans General Hospital Dermatologic and Cosmetic Clinic, Laser and Photonics Medicine Visiting Physician, Yale New Haven Hospital Surgical Resident, Society of the ROC, deputy secretary-general of Chinese Society of Department of Surgery, Taipei Medical University Hospital Cosmetic Surgery and Anti-aging Medicine and the reviewer for Journal of Cosmetic Dermatology.

HU Sindy, HU, Sindy is currently the Vice Superintendent of Chang ISRAELI Hadar, Dr. Hadar Israeli is a prominent and pioneering Gung Clinic of Chang Gung Medical Foundation in Taiwan. Dr. HU plastic reconstructive surgeon with extensive experience in obtained her medical degree from Chung Shan Medical University, post-bariatric body-shaping, burn treatment and reconstruction as Taiwan. She has a master degree of clinical medicine from Chang well as breast reconstruction, and laser surgery and treatment. Gung University. She is an associate professor of department of Currently a partner at Winkler Clinic, utilizing her highly skilled dermatology in Chang Gung Memorial Hospital. She is also an expertise in non-invasive laser cosmetic treatments of the face and executive director of Food and Drug Administration in Taiwan. body contouring. She leads a laser treatment center specifying in reconstructive cosmetic applications

HUANG Allen Yao-Lin , CEO of Charming Beauty Clinic in JUNG Wonsug, Wonsug Jung is currently an research professor Taipei. One of the pioneers of using Restylane Skinboosters in in Department of Anatomy in Yonsei University, College of Medicine. Taiwan, his areas of specialty include using a unique multi-layer Dr. Jung earned his Doctor of Medicine degree and Ph.D degree, injection technique to treat the tear trough deformity as well as the both at South Korea's Yonsei University. Dr. Jung's main research invention of exclusive techniques of using Restylane Vital for facial theme is clinical anatomy related to the aesthetic medicine and has hydro-lifting and rejuvenation. He is trainer for Plastic Surgical Assoc. published papers in Dermatol Surg, J Plast Reconstr Aesthet Surg, (China), Taiwan Surgical Assoc., and laser trainer for the Medical Int J Mol Sc, J Korean Med Sci, Anat Cell Biol, Korean J Anat and Assoc. of the Republic of China. Korean J Phys Anthropol.

HUANG Jeff Chen-Chieh , Dr. Jeff Huang is a board certified KAO Chao-Hsing , Segmental vitiligo(SV) is an acquired dermatologist and internal medicine physician in Taiwan. His depigmentary disorder resulting from loss of functional melanocytes. expertise is mainly on injectables and energy-based devices. He’s Autologous regenerative therapies in SV include various been invited to many countries to share his experience, such as phototherapies, surgical grafting, and platelet-rich plasma intradermal China, Australia, Indonesia, Philippine, Malaysia, Thailand, etc.. He injection. In phototherapies and PRP injection, it showed marginal or practices both in Taiwan and in China; therefore he is exposed to a perifollicular repigmentation. In surgical grafting, the survival, great variety of injectables and devices. proliferation, and migration of living transplanted melanocyte are predictable.

HUANG Ching-Hsin, Speaker experiences: 1. 2017 IMCAS Asia KASRAEE Behrooz, Dr. Behrooz Kasraee is dermatologist and Bali Picosecond for facial rejuvenation-Asian population experiences researcher in the field of skin pigmentation. He identified a series of & The latest trend of female genital rejuvenation 3. 2018 1st AMWC new skin depigmenting agents such as methimazole, ebselen and Asia, Taiwan (1)The trend of non-invasive labial rejuvenation isoniazide. Dr. Kasraee has set forth the concept of H2O2-mediated (2)Atrophic acne scar treatment experience with 755nm picosecond melanin synthesis and its role as a defence mechanism against laser 3. 2018 12th IMCAS Asia and 8th ITCAM Melasma and atrophic oxidative stress. He is at the origin of novel in vitro methods for acne scar treatment experience with picosecond laser melanosomal transfer measurement. Dr. Kasraee is founder & chairman of Scientis & Swiss Vitiligo Center.

HUANG Ching-Yu , I am a dermatologist from Taiwan. In my KENCANAWATI Anne Carolina , Dr. Anne now taking post clinic, patients suffering from paronychia account for major proportion graduate for Anti-aging medicine in Udayana Univerisity, Bali. She of my daily practice. In the past few years, I have been applying nail had become a speaker in several congresses, such as Mesenchymal braces to treat paronychia with satisfactory results. In nail brace Stem Cell for Anti-Aging from Stem Live Indonesia, International workshop, I would like to share my experience of how to improve Cruise Seminar about “Face Lifting before and after with PDO patient's outcome by combining nail braces and other therapies. Absorbable Thread” in Seoul 2016 and speaker in IMCAS Paris 2018 about "AMStemCell For Wound Healing (facial scars). She owns an aesthetic clinic in Jakarta under the name Michele Anne Clinic.

HUANG Patrick Po-Han , Dr. Huang is actively involved in KIM Hong-Seok , Top Graduated, Dong-A University Medical scientific research of dermatology and development of School Academic committee, the Association of Korea state-of–the-art techniques. He has published more than 20 Dermatologists Director, the Korean Society for Anti-aging peer-reviewed articles in SCI journals and received 143 citations in Dermatology Director, the Korean Society for Skin Type Research the top 5 publications. He has served as an Executive Director, Director, the Korean Society of Cosmetics and Cosmetology Key Taiwanese Dermatological Association since 2012. In 2013, he Opinion Leader, Korea L'Oreal SkinCeuticals Key Opinion Leader, established the Taiwan Dermatology Aesthetic Conference, currently L'Oreal Cerave APAC Key Opinion Leader, Pierre-Fabre Korea one of the largest international aesthetic dermatology meetings in Advisor, Korean Beauty Magazine Cosmetic Channel Asia. HUANG Peter Yao-Chu , Dr. Peter Huang currently heads the KING Walter, Dr King is the Director of Cosmetic Central, Plastic & Rebecca Cosmetic Center. He has held position in various hospitals Reconstructive Surgery Centre, Robotic Hair Transplant Centre and in Taiwan including the role of Plastic Surgeon for Cathay General Medical Aesthetic Laser Centre in HK. His Major Former Clinical Hospital and Attending Doctor at the Plastic Surgery Department of Appointments included: Professor of Surgery at the Chinese Taipei Medical University Hospital.


Dr. Huang University of HK; Fellow/ Surgical Assistant at Massachusetts received his medical degree from the China Medical University in General Hospital, USA. Dr King was the President of the HK 1989. After which, he commenced his houseman ship in Cathay Association of Cosmetic Surgery, the HK Surgical Laser Association, General Hospital and subsequently specialized in plastic surgery.


HUANG Yu-Chen , Current position Attending doctor in KO William Wei-Chih , Attending Physician, Cosmetic Dermatology, Wang Fang Hospital, Taipei Medical University, Taipei, Dermatology Taipei Medical University Hospital (Taiwan) Certified Taiwan 2010.07-2014.06 Resident in Dermatology, Wang Fang Clinical Trainer and Speaker: • Galderma certified injectable clinical Hospital, Taipei Medical University, Taipei, Taiwan 2009.07-2010.06 national trainer/speaker • Juvederm certified regional cosmetic Resident in Surgery, National Taiwan University Hospital, Taipei, treatment trainer/speaker • Merz certified injectable trainer/speaker • Taiwan 2003.07-2009.06 School of Medicine at Fu-Jen Catholic Picolaser (Picoway and Picosure) national speaker • Ulthera, University Thermage, Profound national speaker

HUANG Yu-Ming , Dr. Yu-Ming Huang is a board-certified KONTUREK Peter C. , Professor of Internal Medicine and dermatologist from Taiwan. He completed his residency training in the Gastroenterology at the University Erlangen-Nuremberg, Germany. Department of Dermatology at National Taiwan University Hospital. Head of the Department of Internal Medicine at the Thuringia Clinic He is currently serving as an attending physician of several clinics in Saalfeld. Fellow of the American Association of Gastroenterology. Taipei City and is also an adjunct attending physician at NTU Scientific research: gut microbiota, interplay between gut microbiota Children’s Hospital. He has a wide range of interests in many different and brain-gut axis, fecal microbiota transfer, pathogenesis of irritable dermatological fields, including acne, rosacea, pediatric dermatology, bowel syndrome. More than 260 original peer-reviewed publications and aesthetic dermatology. and 15 book chapters.

HUANG Hui-Peng, Huang, Hui-Peng MD •Dermatologist, Taiwan KUO Hsiao-Ling, Dr. Kuo is attending physician in the Division of •Director, Huang Hui Peng Dermatology Clinic •Member, Taiwanese Allergy, Immunology and Rheumatology at Mackay Memorial Dermatological Association •Resident, Department of Dermatology, Hospital, Taipei, Taiwan. She is also the Vice CEO of the Medical National Cheng Kung University Hospital(1988-1992) •Adjunct Education Project of the Yong-Lin Healthcare Foundation. Dr Kuo attending Physician, Department of Dermatology, National Cheng completed her residency and fellowship at Taipei Veteran General Kung University and Hospital (1992-1999) •International fellow Hospital Dr Kuo is a member of the Taiwan Society of Internal member, American Academy of Dermatology (1998-2008) Member, Medicine, the Taiwan Rheumatism Association, the Chinese Society Taiwanese Society for Dermatological and Aesthetic Surgery of Immunology, and Taiwan Society of Ultrasound KWON Han Jin, is Aesthetic Dermatologist & Surgeon, currently LI Jack Yu-Chuan , A pioneer of AI in medicine, medical President of Dermaster Clinic Network. President of International Informatics research and a dermatologist in Taiwan - has been the Aesthetic Medical Association and Medical Alopecia Association of Principal Investigators of many national projects in Electronic Health Korea. Dr. Kwon is also Professor of Seokyung University, College of Record, Patient Safety Informatics and Medical e- learning. Beauty & Cosmetics. He is member of several prestigious scientific associations.

LAI David Ying Ching , Dip ABAAM (2004 Chicago), Dip LI Ko-Jen, Dr. Li is the Attending Physician, Department of Internal Antiaging Med Therap., 2005 Belgium ). Genosense Diagnostics Sci Medicine, in National Taiwan University Hospital. He received Advisor (2006 to 2011). Scientific Coordinator and Lecturer for medical education at National Yang Ming University in Taiwan, and AMWC congress and other Anti-Aging conferences since 2005. furthered he got PhD at the Institute of Clinical Medicine, National Scientific Director for Anti-Aging Congress organized by Yang Ming University. His current interests and expertise include Euromedicom in partnership with Mcgill Medical School in Montreal rheumatoid arthritis, and systemic lupus erythematosus. He is also an (2009). Member of International Society of Gynecological instructor of the Section of Rheumatology at Taiwan Society of Endocrinology (Geneve) & ISGE Certified Practitioner (2019) Ultrasound in Medicine.

LAI Po-Ju , Dr. Lai obtained his medical degree in 2007 form LIANG Ben Chung-Pin , Dr. Liang is a professional training Chung-Shan Medical University, Taiwan. Now, he serves as consultant of micro-injections for international medical companies Attending Physician in Dermatology at Chung-Shan Medical such as Galderma, Merz, Teoxane, Sinclair and IPSEN in Asia. Now University Hospital. His strong interest in the treatment of atopic he is focusing on promote the use of cocktail therapy : a rejuvenation dermatitis, pediatric dermatology and psoriasis has inspired him to set application that integrates thread lifting and subdermal filler. up his personal website (https://pojulai.blogspot.tw/) for patient Moreover, he has implemented a project called Live, Lasting, Lifting education in these fields in 2016. The number of the page views of V-shaped, which is designed for all age generations. His career has reached to 900,000. covers most of the major cities in Asia.

LAI Feng-Jie, Graduate Institute of Medicine, Kaohsiung Medical LIAO Yi-Hua, Yi-Hua Liao is an associate professor of Department University M.D. Ph.D. 9/2001 Medicine 2006.8~ Dermatology, Chi of Dermatology, College of Medicine, National Taiwan University. She Mei Medical Center, Attending Physician and Director 2014.8~ Center received the M.D. degree from National Taiwan University College of for General Education, Southern Taiwan University of Science and Medicine, and Ph.D. degree from the Graduate Institute of Pathology, Technology, Associate Professor 2012.12~2014.1 Department of National Taiwan University. She is currently the director of the Laser Applied Cosmetology, National Tainan Institute of Nursing, Associate and Photonics Medicine Society of the Republic of China, and the Professor Fields of Specialty: Dermatology, Oncology, Histology director of the Taiwanese Dermatological Association.

LAM Phoebe Kar Wai , Dr. Phoebe KW Lam practices in LIM Joyce, Dr Joyce Lim Teng Ee is a skin specialist, recognised cosmetic medicine and surgery mostly dedicated to fields of face and and accredited by the Ministry of Health, Singapore and the Ministry body contouring in Hong Kong. As an avid learner in aesthetics, of Health in Malaysia. She is also a registered doctor with the Health holding a few degrees, Fellowships and Diplomas in Korean College Authority in Hongkong SAR . of Cosmetic Surgery (KCCS) , American Academy of Aesthetic Medicine (AAAM), American Academy of Anti-aging (A4M), and a Master degree in Practical Dermatology with University of Cardiff, UK.

LAN Cheng-Che , Dr. Lan is the Professor and Chair of LIM Ting Song , Dr Tingsong Lim actively involved in many Dermatology Department, Kaohsiung Medical University. He enjoys academic research and training in Asian facial and body aesthetics, clinical practice as much as academic research. With regards to his clinical application of fillers’ rheology, facial overfilled syndrome, academic activities, some of them are listed as follows: - Associate pigmentary disorders, laser medicine and regenerative medicine. Editor, Photodermatology, Photoimmunology, Photomedicine, 2018- Graduated from Tohoku University School of Medicine under the -Secretary general, Taiwanese Photomedicine Society 2017- Monbusho Scholarship, Dr Lim speaks 4 languages (English, -Treasurer, International Federation of Pigment Cell Societies 2017- Mandarin, Malay, Japanese) fluently. He frequently speaks and conduct trainings regionally and world-wide.

LEE Geun Soo , Geun-Soo Lee, MD, Ph D is Dermatologist. LIN Shang-Li , Shang-li Lin, MD is a Dermatologist. In 2009, he Currently, he is the director of Drs. Woo & Hann’s Skin & Laser founded Shang-li dermatologic & aesthetic Clinic in Taipei, Taiwan. Center. He had been contributed to scientific committee of the He has extensive experience is also a global trainer and speaker in Association of Korean Dermatologist as scientific secretary from 2009 the filed of dermatologic laser surgery, skin lifting and tightening to 2013, and financial secretary now. He wrote clinical studies and devices and dermal fillers, He is a Member of Taiwanese editorials about fractional and non-ablative lasers, light source, and Dermatological Association. In the competition of 3rd anti-aging and acne treatment. His main clinical focuses are acne treatment, pigment beauty trophy 2015-2016, he is also the winner of the best case in treatment, and laser treatment. non-surgical facial rejuvenation.

LEE Yung-Yi , Yung-Yi Lee is a lecturer attending physician of LIN Chrang-Shi, Clinical Professor, Department of Dermatology department of dermatology at Chang Gung Memorial Hospital, Taipei and Family Medicine, National Yang-Ming University, Taiwan branch. He received 1-year resident training of department of urology Director, Dr. Lin Skin Clinic, Taipei,Taiwan Board Supervisor, at National Taiwan University Hospital. In 2009, he joined the training Taiwanese Dermatological Association Chairman, Taiwan Straits system of residency at Chang Gung Memorial Hospital. In 2013, he Exchange Academy for Dermatology and Esthetic Medicine Vice became an attending physician of department of dermatology at Chair, International Chinese Dermatologist Association Vice Chair, Chang Gung Memorial Hospital. His interest focuses on dermatologic Asian Dermatological Association Board Member, Asian Academy of surgery. Dermatology and Venereology

LEE Mei-Ching, Lee, Mei-Ching, MD & MBA Attending doctor of LIN Liang-Chen, Dr. Lin is broad certified dermatologist / Director Dermatology, Chang Gung Clinic / Taipei & Taoyuan, Chang Gung of Lin Liang Chen Dermatologic Clinic at Hsinchu City, Taiwan. Memorial Hospital Assistant Professor of Dermatology, Chang Gung Besides the skin disease care, Dr. Lin is also well known for aesthetic Memorial Hospital Associate Chief, Aesthetic Medical center, Chang treatment using picosecond Laser / PLLA / hyaluronic acid and focus Gung Clinic Director, DermaFormula, Formosa Biomedical on combined rejuvenation treatment by biostimulator (PLLA) and Technology Corp. Medicine collage, Taipei Medical University Taipei, energy based device. Dr. Lin is now the training consultant and Taiwan (1992 - 1999) Management College, Natioanl Taiwan speaker of Cynosure Picosure / Galderma Aesthetic Injector University, Taiwan (2015 - 2018) Academy / Lumenis M22 / Merz.

LEYLEK Ozgur , He is an ObGyn for 20 years. He works on LIN Jeng-Hsien , Dr. Lin is a board-certified dermatologist. He cosmetic gynecology for last 10 years and he has a few registered graduated from National Taiwan University, and finished his techniques for non surgical gynecologic procedures. He is also a dermatology training in National Cheng-Kung University Hospital. global master trainer on aesthetic gynecology. He is the founder and Besides skin diseases, he is also interested in the injectables, president of Turkish Aesthetic Gynecology Association-TEJD, neurotoxins, and energy-based devices. He has been invited as a foundation and scientific member of ISRAIT, founder and scientific speaker or instructor on aesthetic topics in several domestic and president of Female Aesthetic Gynecology Academy-FAGA, member international conferences. He is now the chief of Dr. Lin's of TJOD, TUJD, MESTDER, MEZODER and ESAG. Dermatology Clinic in Kaohsiung.

LI Chih-Wei , Director , Delicate Clinic Attending, Ton Yen LIN Chia-Chi , Chia-Chi (Josh) Lin is the Director of Phase I Aesthetic Clinic Board of Certification: Taiwanese Board of Center, Department of Oncology, NTUH and Associate Professor, Dermatology Membership of Scientific Society: Member, Taiwanese Graduate Institute of Clinical Medicine, NTUCM. He received his MD Dermatological Association Member, IMCAS International Master degree, PhD degree, and his specialty training in Medical Oncology at Course on Aging Skin Member, Taiwan Society of Neutron Capture the NTUCM. He has authored more than 30 peer-reviewed Therapy Trainer for Restylane Member of the Control, Taiwan manuscripts. His main research interests include early phase drug Aesthetic Medicine Quality Assurance Association development as well as novel therapies for lung cancer, esophageal cancer, and thyroid cancer.

LI Chien-Nien , Dr. Chien-Nien Li is a dermatologist and LIN Yi-Ting, Dr. Yi-Ting Lin is a consultant dermatologist working dermatological surgeon based in Taiwan. Currently, the Director of at Chang Gung Memorial Hospital. She specialized in the Taipei JFM Clinic. He is an internationally renowned expert in the Immunodermatology, especially psoriasis, atopic dermatitis, chronic field of aesthetic dermatology and focuses on the application and use urticaria, and type I hypersensitivity reaction. She is dedicated in of fillers, botulinum toxin, lasers , energy-based devices and dermal improving the life quality and psychiatric impact related to those stem cells. He is currently a Ph.D. candidate, focusing on dermal chronic diseases by prompt effective treatment and raising stem cell research at the Graduate Institute of Clinical Medicine, awareness of mental health importance. Taipei Medical University. LIU Hen-Yu , Dr. Hen-Yu, Liu obtained his Ph.D. degree from NG Chau-Yee , Dr. Chau Yee (Charlene) Ng is a certified Graduate Institute of Medical Sciences, Taipei Medical University, dermatologist, currently practicing in Chang Gung Memorial Hospital, Taiwan. He joined Taipei Medical University to pursue the stem cell Linkou/Taipei. She is a young rising star in dermatology and had research and regenerative medicine. Now, he also is the chief received several research award. Her interest mainly focus on vitiligo technology officer of METATECH(3224.TW) who organize a new research and surgery. research for Development of advanced cell sheets and the process optimization on regenerative medicine.

LIU Li-Lin , With 22years of experience in aesthetics, Dr. Liu NOVAKOV Aleksandra , Aleksandra Novakov Mikic graduated specialized in facial anti-aging, skin rejuvenation, skin care and body from the Novi Sad Medical School in Serbia in 1995 and received a contouring. As a pioneer in the field of aesthetic, Dr. Liu integrate all PhD in Obstetrics and Gynecology from the same university in 1999. treatment tools to promote patients being younger. In 2000 she received a Diploma in Fetal Medicine from the Fetal Medicine Foundation at Harris Birthright Centre at Kings College, London. Since 2013 she has been a Consultant in Obstetrics and Gynecology, subspecialist in Perinatology at the Policlinic 'Novakov et al.' in Novi Sad.

LU Sophie Pei-Hsuan , Dr. Sophie Lu is a board-certified PARK Young-Woon , Medical Doctor Board-certified dermatologist based in Taipei, Taiwan with the fellowship training in Dermatologist, Representative Director, Villa de Skin Dermatology plastic surgery. Dr. Lu is honored to be the first Taiwanese and Plastic Surgery Clinic Academic Activity American Academy of International Traveling Mentor in the American Society for Dermatology American Society for Laser Medicine and Surgery Dermatologic Surgery. She is committed to her ongoing education American Society for Dermatologic Surgery International Society for and science-based care so that she can offer patients the most Dermatologic Surgery innovative surgical and nonsurgical options, while maintaining the individuality and naturalness of each patient.

LU Chun-Wei , Lu Chun-Wei is an attending dermatologist of PATHAK Surajit , Dr. Surajit Pathak is an Indian born research dermatology departmentof Chang-Gung Memorial Hospital, scientist, advisor and an Associate Professor at CHETTINAD consultant of Taiwan severe cutaneous drug reaction association and ACADEMY OF RESEARCH AND EDUCATION, Chennai who has deputy secretary general of Taiwan evidance based medicine multiple expertise encompassing cancer biology, stem cell and association. His work focuses specifically on severe cutaneous regenerative medicine. He started active research in the year 2001 adveres reaction (SCAR), cutaneous viral infection and management and received his Ph.D from University of Kalyani, INDIA in 2007. of cutaneous reaction of anti-cancer therapies. Worked in USA, Italy and Sweden over 10 years with 1010 citations. Dr. Pathak has published over 60 papers till date.

LU Po-Hsuan , Education M.D., School of Medicine, National PENG Yu-Pin , is dermatologist in Taipei. He is specialized in Taiwan University, Taipei, Taiwan Ph.D., Graduate Institute of Common Dermatologic Disease - Aesthetic Medical Treatment - traditional Medicine, National Yang University, Taipei, Taiwan Current Laser and Photonics Medicine - Dermatologic Surgery - Position 2017- Attending Physician, Department of Dermatology, BOTOX&JUVEDERM Injection - MERZ Radiesse Injection - Mackay Memorial Hospital, 2019- Associate professor, Department of SUNMAX Collagen Injection - GALDERMA Restylane Injection - Medicine, Mackay Memorial College LUMENIS Trainer

MANUSKIATTI Woraphong , MD, is Board certified PENG Peter Hsien-Li , Dr. Peter Peng is a board certified dermatologist. Appointed since 2007 as Professor of Dermatology, Dermatologist / Dermatological surgeon in Taiwan.Dr. Peng serve as Department of Dermatology, Siriraj Hospital, Mahidol Univ. (Bangkok, executive director, Taiwanese Dermatological Society(TDA) ; director, THAILAND), Among several expertises, he is well-known for being an Taiwanese Society for Dermatological& Aesthetic Surgery(TSDAS), expert in lasers and energy-based devices. He has over 60 articles President, President, Laser and Photonics Medicine Society of the published in peer-review journals and also invited speaker at many R.O.C. With two decades of experience, Dr. Peng is a international dermatology congresses. world-renowned expert in toxins, fillers, lipolysis, lasers, EBD, thread lift fields or a combination of above.

MARINI Leonardo, Medical Director of The Skin Doctors’ Center PIRAYESH Ali , is an internationally renowned Plastic Surgeon - Trieste (Italy), former President of ESLD and ESCAD, presently and Owner of Amsterdam Plastic Surgery Clinic. He is President of Chairman of the EADV Task Force for Laser Dermatology, is the Dutch Society of Aesthetic Plastic Surgery, Executive Council specialized in Dermatology and Venereology as well as General Dutch Society of Plastic Surgery. He is a consultant of University Surgery. He has been working in the area of Dermatologic Surgery Hospital Gent with top focus on Burns &Tissue regeneration and and Aesthetic Dermatology for more than 25 years. After his medical co-inventor of Glyaderm artificial skin. His specialist interests include: degree at the University of Trieste Medical School, he trained in USA, Aesthetic surgery of the face & breast, body contouring, Lasers and Germany, France, Australia and New Zealand. injectables.

MARTIN Druanne , Druanne has 20 years of experience in the RAVICHANDRAN Simon , Mr Simon Ravichandran trained as publishing industry. She has been with Wolters Kluwer for 9 years as an Ear, Nose and Throat surgeon in Glasgow. He co-founded the a Senior Publisher, overseeing all aspects of journal publishing for Clinetix Medispa group in Scotland and is the founder and chairman large society publications, including the journal Dermatologic Surgery. of the Association of Scottish Aesthetic Practitioners and has lectured Prior to her time at Wolters Kluwer, she spent 4 years at Elsevier as and demonstrated globally. Dr Simon Ravichandran runs the an Acquisitions Editor. Early in her career, she worked as a Aesthetic Training Academy in Scotland and is known for his technology publishing vendor at both Impelsys, Inc. and OverDrive, dedication and passion for teaching in all areas of aesthetic medicine. Inc.

MENDEZ ESPANA Mauricio , Medical Doctor at University ROJANAMATIN Jinda , Currently the Director, the Bureau of Xochicalco, México Master in Clinical Dermatology, University CEU Medical Strategy, Ministry of Public Health, Thailand. Dr. Rojanamatin Cardernal Herrera, Spain Expert Degree in infectious Dermatology, is also an Vice President of the board of Dermatological Society of University CEU Cardenal Herrera, Spain Aesthetic Medicine at Thailand. He has been invited as speaker at several prestigious American Academy Aesthetic Medicine; Union International Estetique international meetings, his major topics of interest are skin laser Medicine Master Injector and International Speaker surgery, as well as, Botulinum toxin and Fillers.

MIYATA Nariaki , M.D., Ph.D. Director, Miyata Plastic Surgery SAMIZADEH Souphiyeh, Dr Souphiyeh Samizadeh graduated and Skin Clinic, Tokyo, Japan Japan Society of Aesthetic Plastic from King’s College London.She is a visiting associate professor at Surgery (Councilor) Japan Society for Laser Surgery and Medicine Shanghai Jiao Tong University, the founder and director of the Great (Councilor) Japan Society of Plastic and Reconstructive Surgery British Academy of Aesthetic Medicine and Revivify London clinic. (Board certified) She's an honorary clinical teacher at King’s College London and Queen Mary University of London. She speaks nationally and internationally and is involved in ongoing research in Aesthetic Medicine.

MOEY Christie , Dr Christie obtained her medical degree from SCHERER Max-Adam, Dr. Max-Adam Scherer, plastic surgeon, Nizhny Novgorod State Medical Academy, Russia in 2009. After dermatologist, cosmetologist - at I.M. Sechenov First Moscow State finishing her primary care services, Dr Christie started venturing into Medical University, Basic medical education as general Medical Aesthetics. She became one of the only few board certified practitioner/physician, at B.V. Petrovsky Russian Scientific Surgery Aesthetic Physician in 2017, obtaining the License of Credentialing Center, Fellowship in plastic surgery. Presently Dr. Scherer has his and Privileging (LCP) conferred by the Ministry of Health Malaysia. own private practice in Moscow. His special interests include low Her areas of interest include laser systems, energy based devices invasive face and neck aesthetic plastic surgery ensuring maximally and body aesthetics. natural looking rejuvenation.

NADELA Rosalina, DR ROSALINA NADELA is a dermatologist SEO Suk Bae, Head Doctor, SAS Dermatologic Clinic Member of in private practice in the MedDERM Asia Clinic in the Philippines. She the Korean Dermatological Association Member of General Affairs obtained her MSc. Clinical Dermatology from the St John’s Institute of Manager, Medical Secretary of the Association of Korean Dermatology, University of London, England. Her field of interest is Dermatologists Member of The Korean Society for Aesthetic and aesthetic dermatology, laser surgery, botulinum toxin injections, Dermatologic Surgery Member of Korean Aesthetic Surgery & Laser dermal fillers. She is a Fellow of the Philippine Dermatological Society Society Member of Korean Journal of Cosmetic Dermatology Member and the American Academy of Dermatology. of Korean Skin Laser Society Resident in Dermatology Dept. Hallym University Gangdong Sacred Heart Hospital SERRANO Gabriel , Dr Gabriel Serrano is Consultant TSENG Fang-Wen , Fang-wen TSENG M.D. is the medical Dermatologist and the owner of the Clinic Dr Gabriel Serrano in director of Taoyuan Milano Aesthetic Clinic in northern Taiwan. He is Valencia. He worked at the University General Hospital as Clinical a dermatologist who specializes in fillers, BTXA, EBD, fat grafting, Chief of the Dept. of Dermatology for more than 25 years. He opened and body contouring. As an advisor/ trainer for Merz, Galderma, his own clinic in 1978 and founded Sesderma Laboratories in 1989. Allergan, Cynosure & Solta, Dr. Tseng is generous in sharing his Sesderma was the first laboratory in Spain to launch a line of experiences to fulfill cosmetic physicians’ restless appetite for treatments with glycolic acid, and is now the only one which develops pursuing perfection. a wide variety of products using nanotechnology.

SHAH Falguni , Dr Falguni Shah, a leading dermatologist and TSENG Han-Chi, Graduated from National Yang-Ming University cosmetologist is founder and owner of Radiance Clinic in Mumbai, with honors. Dr. Tseng received full dermatologic training at India, which caters to several celebrity patients in India and abroad. Kaohsiung Chang-Gung Memorial hospital. She is currently the She specializes in providing non surgical Facial Rejuvenation and attending physician at Kaohsiung Chang-Gung Memorial hospital. Anti-ageing treatments. Practicing since last 15 years she has strived She also teaches as lecturere at Yuh-Ing college of health and hard to bring science to the world of beauty and has taken specialized management. She is interested in medical dermatologic diseases, training in Lasers and Advanced cosmetic procedures infectious diseases and aesthetic medicine.

SHEEN Yi-Shuan , Education: 1997-2004 MD, Department of TSENG Jonathan Te-Peng , Dermatologist specialist, now Medicine, College of Medicine, Kaohsiung Medical University, serving as the Chief of Department of Dermatology at Taiwan Kaohsiung, Taiwan 2007-2009 MS, Graduate Institute of Clinical Adventist Hospital. After obtained his University degree with the Medicine, College of Medicine, National Taiwan University, Taipei, University of Toronto, School of Medicine, Department of Taiwan 2014- 2017 PhD, Graduate Institute of Pathology, College of Immunology, he continued his medical training with the Taipei Medicine, National Taiwan University, Taipei, Taiwan Clinical Medical University, School of Medicine. He has acquired further Responsibility: Dermatologic surgery special clinic Cosmetic surgery training of dermatologic surgery (Hair restoration, skin tumor, nail and laser special clinic surgery) in U.S.A and Japan.

SHIH I-Hsin , Short biography of I-Hsin Shih, MD Born 1959 in TSENG Yu-Ju, I am Yu-Ju Tseng, who graduated from Kaohsiung Taipei, Taiwan. Graduated from Taipei Medical University 1984. Medical University. I completed my training program at the Dermatology residency in Chang Gung Memorial Hospital (CGMH) Department of Dermatology, Kaohsiung Chang Gung Memorial 1986~1990. Visiting scholarship in Stanford University 1994~1995. Hospital. My academic training and research experience at Attending physician of pediatric dermatology department and clinical Kaohsiung Chang Gung Memorial Hospital to date have provided me associate professor of CGMH. Active member of TDA, ADA and SPD. with an excellent background in cutaneous infection with mycobacteria. It is an honor to have the opportunity to give a talk in this conference.

SHIH Tsung-Hsien , is director of Shih Tsung Hsien TU Wei-Ting, Tu, Wei-Ting has been an attending physician in the Dermatological Clinic in Kaohsiung city, Taiwan. dermatology department of National Cheng Kung University Hospital since 2017. His main clinical and research focus is nail surgery, cutaneous surgery, and genodermatoses. He graduated from National Cheng Kung University, College of Medicine, School of Medicine in 2011, after which he received his dermatology residency training in Taipei Medical University - Shuang Ho Hospital from 2013 to 2017.

SOFRA Xanya , Dr Sofra has doctorates in Neurophysiology VAN EIJK Tom, Born in 1969, based in Amsterdam, Dr. Tom van (London University), & Clinical Psy (New York). Director of Research, Eijk is one of the most influential aesthetic practitioners on the globe Pioneer, & Inventor of New Technology for IELLIOS LTD UK, USA since he developed the Fern Pattern Technique, introducing it in and Hong Kong. Research in Signalling Pathways, Protein Sweden in 2005. Besides working for companies like IBSA, Galderma Communications & Hormonal Regulation for anti-inflammation, pain, and Arthrex/Croma the majority of his teaching is independent from skin repair, detox, health & fitness. Worked with Gerald Pollock, the industry. The Tom van Eijk Academy enables him to give co-inventor of the Pacemaker in London University, on NFS motor unbiased advanced intimate hands-on training for experienced nerve signalling for MS, pain and muscle atrophy. injectors worldwide.

STANKOVIC Nenad , Internationally renowned as a leading VIZINTIN Zdenko, Zdenko Vizintin, BSEE (Dipl. Eng.), MSc/MBA lecturer, trainer and expert in facial aesthetics. President of has been working in laser technology for almost 40 years. Throughout Anti-Ageing Institute (AAI) and medical ambassador of International his professional career he has been deeply involved in R&D and Plastic Aesthetic Residence (IPAR). production of various laser systems for different industries. In his current position in Fotona as Program Director he is responsible for the Applications Development and Clinical Affairs. He is actively involved in new medical laser application development and validation through clinical studies.

SUN Pei-Lun, Pei-Lun Sun is an attending physician and assistant VOROPAI Daria , Dr Daria Voropai, aesthetic practitioner. professor in the Department of Dermatology, and the head of Throughout her medical career, Dr.Voropai has taken part in Research Laboratory of Medical Mycology, Chang Gung Memorial numerous Head and Neck anatomical dissection projects. Post Hospital, Linkou Branch, Taiwan. He has the specialty in medical qualification, she spend several years working in in General Surgery mycology, from diagnosis and treatment of mycoses to the isolation of whilst successful establishing and running her own aesthetic clinic in pathogenic fungi from the environment. His long-term interest is in the The Netherlands. Dr.Voropai is an international trainer now based in study of tinea capitis, zoonotic dermatophytosis, onychomycosis, and London. Her predominant focus is applied Facial Anatomy and veterinary mycology. 3D-sculpting of the face.

TING Sze-Wen , Dr. Sze-Wen Ting received her medical degree WANG Chao-Chin, Chao-Chin Wang, MD, is a dermatologist in from the School of Medicine, National Taiwan University. She further private practice. Dr. Wang is a recognized expert in minimally completed her residency and fellowship training in the department of invasive facial rejuvenation, including energy based devices, dermatology at Chang Gung Memorial Hospital. She is now a injectables and thread lifts. Being a frequently invited speaker, he broad-certified dermatologist in Taiwan and serves as an attending held a faculty position at college, giving lectures on aesthetic physician at Chang Gung Memorial Hospital. She is enthusiastic medicine. He currently serves as a board of director and vice chair of about hair and scalp disorder, scar revision and medical dermatology. public affairs committee in Taiwanese Dermatological Association and organizes the event of AMWC Asia-TDAC.

TSAI Ren-Yeu , Prof. Tsai is a dermatologist and dermatologic WANG Wei-Ming, is dermatologist in Taipei, Taiwan. surgeon for 30 years in Taiwan. He is the first president of Taiwan society for dermatological and aesthetic surgery. He also served as associate editor of Jounal of cosmetic dermatology, contributing editor of Dermatologic Surgery, consulting editor of Dermatologica Sinica and editor of Chinese Joural of Dermatology.

TSAI Tsen-Fang , TF Tsai is professor in department of WANG Yen-Jen , Dermatologist, Taiwan Present affiliation: dermatology, National Taiwan University Hospital. He had also Department of dermatology, MacKay Memorial Hospital, Taipei, served as the editor-in-chief for Dermatologica Sinica for 7 years. In Taiwan Field of interest: Skin cancers, Mohs micrographic surgery, medical dermatology, since 1992, he published nearly 300 peer Vitiligo, Optical Coherence Tomography and Confocal Microscopy review articles on psoriasis, viral infection, hair loss, cosmetic dermatology and dermatopathology. Also he has extensive experience on regulatory affairs of drugs, devices and cosmetics..

TSAI Ya-Chu , Attending Physician, Department of Dermatology, WANG Shiou-Han , Shiou-Han Wang, MD CURRENT Far Eastern Memorial Hospital, New Taipei City, Taiwan Research POSITIONS Superintendent, Skin168 Institute of Dermatology, Physician, Department of Dermatology, National Taiwan University Taipei, Taiwan Adjunct Staff, Department of Dermatology, NTUH, Hospital, Taipei City, Taiwan Resident Physician and Fellowship, Taipei, Taiwan EDUCATION Doctor of Medicine (MD), College of Department of Dermatology, Far Eastern Memorial Hospital, New Medicine, National Taiwan University(NTU) Master of Science in Taipei City, Taiwan Resident Physician, Department of Internal Electrical Engineering (MSEE), Graduate Institute of Biomedical Medicine, Chang Gung Medical Hospital, Taoyuan County, Taiwan Electronics and Bioinformatics, NTU Bachelor of Science in Mechanical Engineering (BSME), NTU WANG Jen-Yu, is dermatologist in Taipei, Taiwan. YANG Ching-Sheng, Chang Gung University of medicine Chang Gung Memorial Hospital, department of dermatology

WANG Jann-Yuan, Prof. Wang is the leading researcher in the YONEI Yoshikazu, MD, PhD is presently Professor at Anti-Aging field of tuberculosis (TB), latent TB infection, and nontuberculous Medical Research Center, Graduate School of Life and Medical mycobacteria pulmonary disease in Taiwan. He also serves as a Sciences, Doshisha University in Tokyo, Japan. He is specialist in consultant of the Centers for Disease Control, Taiwan since 2004 and AntiAging Medicine, Gastroenterology and Hepatology. Prof. Yonei is is active in several important expert committees for TB control and also Board Member of the Japanese Society of Anti-Aging Medicine policy making. and (NPO) the Japan Anti-Aging Foundation

WANITPHAKDEEDECHA Rungsima , Associate Professor YU Peter Yu, Dr. Peter Yu Yu received his medical degree from Dr. Rungsima Wanitphakdeedecha is a dermatologist and National Taiwan University, completed his dermatology residency at dermatologic surgeon in Bangkok, THAILAND. She has been serving Cathay General Hospital and fellowship in pediatric dermatology at as a faculty in Dermatosurgery Unit, Department of Dermatology, Northwestern University, Chicago, IL, USA. He maintains affiliations Faculty of Medicine Siriraj Hospital, Mahidol University since 2003. with Cathay General Hospital, Taipei/Sijhih and Saint Mary’s Hospital She has lectured nationally and internationally on the topics of Luodong. His current areas of interest include pediatric dermatology dermatologic surgery, laser, and cosmetic procedures. She has and atopic dermatitis. He is an active member of Society for Pediatric published many book chapters and manuscripts in peer-reviewed Dermatology (USA). journals. WEI Lin-Hung , Professor, Department of Obstetrics and ZABNENKOVA Olga , Olga Zabnenkova, MD, PhD, Gynecology, Medical College, National Taiwan University Attending dermatologist, associate professor. In 1998 she founded a private Physician in Oncology/Obstetrics & Gynecology, National Taiwan practice for dermatology & aesthetic medicine in Moscow, Russia. Dr University Hospital  M.D., Department of Medicine, College of Zabnenkova has intensive experience in BoNT and dermal fillers, Medicine, National Taiwan University  Ph.D., Laboratory of laser resurfacing, acne & scars treatment She is KOL of Galderma, Molecular and Cellular Toxicology, Institute of Toxicology, College of Merz, expert dermatologist of Procter&Gamble. She held a large Medicine, National Taiwan University  EMBA, College of number of international workshops. She has also published more Management, National Taiwan University than 130 scientific articles and books.

WENG Hao-Jui , Dr. Weng is currently chief resident in the ZHOU Guoyu, is professor in Facial Plastic Surgery in Shanghai, Department of Dermatology at National Taiwan University Hospital. China. He earned the M.D degree in 2006 at National Taiwan University. Prior to his residency, he received his PhD and post-doctoral training in neuroscience at Johns Hopkins University from 2008 to 2015 with the pioneering works in itch and pain. He is interested in the roles of the nervous system in the pathogenesis of itch for dermatological disorders.

WONG Sky Tin-Hau, Dr Wong graduated from Medical Faculty of Univeristy of Hong Kong. He then pursued his post graduate Master Degrees in Aesthetic Plastic Surgery and Dermatology in England. Dr Wong is the keynote speaker in world-wide conferences and trainer of various energy machines, injectables and minimally invasive procedures. He is now a visiting lecturer for various universities. His main interest is Picosecond laser, cutaneous vascular treatment and structural approach for injection.

WU Ying-Chin , Profile • Clinical Professor of dermatology of National Taiwan University Hospital(NTUH) • Founder and Owner of WCLINIC and WSPA • Founder of DR.WU Clinical Skincare • Formal Chairman of Taiwan Dermatology Association

WU Yu-Hung, Dr. Wu is currently the president of Asian Society of Dermatopathology, associate professor and chair of education committee of Taiwanese Dermatological Association, and director of fellowship program accredited by International Committee for Dermatopathology. He has been served as the department chair, chief editor of Dermatological Sinica, and executive committee member of International Society of Dermatopathology. He has published more than 120 scientific articles.

WU Jennifer, I am a dermatologist, an attending physician and a lecturer in Department of Dermatology, Chang Gung Memorial Hospital, Taipei and Chang Gung University, in Taiwan. I served as a visiting investigator under Dr. Mario Lacouture, Director of Oncodermatology Program, at Memorial Sloan Kettering Cancer Center during March 2017-2018. I've focused my research interest on severe cutaneous adverse drug reactions and immune-related adverse events (irAEs) induced by immunotherapies.

WU Nan-Lin , Nan-Lin Wu is a senior attending physician of Mackay Memorial Hospital, and an associate professor of MacKay Medical College. His clinical work focuses on inflammatory/immunological skin diseases such as psoriasis and atopic dermatitis. His research focuses specifically on skin inflammation, and skin photobiology.

YANG Jason Chih-Hsun , Professor. Jason, Chih-Hsun Yang accomplished his training at the Chang Gung Memorial Hospital (CGMH). He was a clinical and research fellow in John Hopkins University and Toranomon Hospital (Tokyo) in year 2000. Dr Yang was the director of the Dermatology Department and Cosmetic Center, CGMH from 2007 to 2016. He was elected as the President of Taiwan Dermatological Association in 2012. Dr Yang’s special interest is in varicose vein, dermoscopy and nail surgery.

YANG Chin-Yi, Dr. Chin-Yi Yang is a dermatologist and pediatric dermatologist from Chang Gung memorial hospital,Linkuo. She had received residency training in Pediatrics in Taiwan University hospital and completed training in dermatology in Chang Gung memorial hospital. She was the recipient of Takeda scholarship and was visiting doctor in Tŕkyŕ Teishin Hospital. She has special interest in atopic dermatitis, vascular lesions and has presented in numerous conferences. Abstracts Pre-Congress Course ABSTRACTS PRE-CONGRESS COURSE

CHANG David Yao-Yu 201D (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: PHLEBOLOGY WORKSHOP 1 DUPLEX ULTRASOUND EXAMINATION Duplex ultrasound has become the gold standard in the investigation of lower-limb venous disease. Mastering scanning technique can help us confirm the diagnosis, recognize the patterns of venous disease and determine the most appropriate treatment for our patients.

CHANG David Yao-Yu 201D (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: PHLEBOLOGY WORKSHOP 1 LOWER LEG VENOUS ANATOMY & PATHOPHYSIOLOGY Understanding of the venous anatomy of the leg is essential to the successful practice phlebology. However, it is complicated and highly variable, as only a small number of vessels are named. It is also very confusing because of many pathological conditions may concur. Careful examination of patients with Duplex ultrasound is the only way of enhancing our understanding of venous anatomy.

CHANG David Yao-Yu 201D (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 12:30 Session: PHLEBOLOGY WORKSHOP 2 COMPLICATION OF SCLEROTHERAPY Minor and temporary complications are very common after sclerotherapy. Recognizing these complication, correct management and careful attention will keep disasters from happening.

CHANG Chi-Hao 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30

Session: NAIL BRACE WORKSHOP

HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results. CHANG Chi-Hao 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP CONSERVATIVE TREATMENT OF PARONYCHIA Ingrown nail is a common condition in which the side of nail plate grows into the soft tissue. The most important way to resolve this contion is relief of irritation caused by the nail plate. There are some conservative way to protect the lateral nail fold from the offending distal nail edge, such as taping, packing, acrylic nail, gutter, and nail braces. Physicians should adopt different kinds of strategies according to the types of ingrown nails to achieve better outcomes.

CHEN Yi-Chin 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30

Session: NAIL BRACE WORKSHOP

HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results.

CHEN Yi-Chin 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP THE CONCEPT OF DIFFERENT NAIL BRACES Nail brace is a non-invasive treatment for patients with ingrowing nail who is afraid of nail surgery or cannot do nail surgery. There are many kinds of different nail braces. Each one has its own characteristic and can use in different conditions. Through the lecture, you can learn more details of different nail braces, their advantages and disadvantages. Besides, you can know how to choose the right nail brace for the right person.

HUANG Ching-Yu 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30

Session: NAIL BRACE WORKSHOP

HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results.

HUANG Ching-Yu 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP COMBINATION THERAPY BETWEEN NAIL BRACE AND OTHER TREATMENTS I am a dermatologist from Taiwan. In my clinic, patients suffering from paronychia account for major proportion of my daily practice. In the past few years, I have been applying nail braces to treat paronychia with satisfactory results. In nail brace workshop, I would like to share my experience of how to improve patient's outcome by combining nail braces and other therapies.

HUANG Patrick Po-Han 201ABC (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS A REVIEW OF EMERGING TOXINS IN ASIA More and more new toxin formulations have recently emerged in Asia. They are mainly from Korean and one is from China. The new Asian botulinum toxin products always promise to be at least equally effective and the only available liquid form in the world, is also from Asia. All Asian toxins are available outside Asia but ONLY ONE approved by US FDA. In this talk, we would like to review all toxins available in Asia and analyze the Asian markets.

LEE Yung-Yi 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results.

LEE Yung-Yi 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP THE CAUSES AND DEVELOPMENT OF INGROWN NAILS Ingrown nails are very common in our daily practice. However, many doctors treat the patients with paronychia in a wrong way because of inadequate knowledge. Thus, dermatologists are ought to own enough basic mechanism of paronychia. If we have the more information of paronychia, we can be more confident to explain and evaluate the patient's situation.

LI Jack Yu-Chuan 201ABC (LEVEL 2) Friday, May 10, 2019 - from 14:00 to 15:30 Session: ARTIFICIAL INTELLIGENCE TECHNOLOGY: HUMAN MAESTROS VS AI AI BASICS AND HEALTHCARE APPLICATIONS Artificial Intelligence (AI) has had a great impact on the healthcare field and will continue to transform health systems radically. Every healthcare professional should arm themselves with the knowledge to face these changes. In light of the AlphaGo program that wins over two of the best Go chess players in the world, Artificial Intelligence (AI) is now back to the spotlight again. Given advice and warnings from some of the top minds like Elon Mush and the late Steven Hawkings, it seems inevitable that AI is going into a fast-pace development in the next few years and likely to impact every aspect of our lives very soon. This talk will describe some of the most important AI applications in healthcare, namely, quality and patient safety, early detection of diseases and individualized prevention. We will also discuss how Big Data and AI will go hand-in-hand in the future of health care for all the stakeholders, in terms of high-performance healthcare and precision medicine.

LIM Ting Song 201ABC (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 13:00 Session: BEYOND INJECTABLES: WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES RESTORING THE ANCHORING COMPLEX FOR BETTER FACIAL CONTOURING Current trends in aesthetic medicine has been focusing on facial volume replenishment with fillers and muscle relaxation with toxins. Dermal filler injection is one of the most commonly performed cosmetic procedure globally. Hyaluronic acid filler is treatment of choice due to its effectiveness in replenishing facial volume. However, continous volume replenishment does not seem to be tackling facial ageing effectively in the long run. Facial rejuvenative treatments that solely depending on volume replenishments not only leads to facial overfilled syndrome (FOS), but could also lead to iatrogenic ageing and continuous distortion of the structures in the face. It is, in fact, very important for us to tackle the anchoring complex, which holds the skin to the bone or fascia, by using biostimulation modalities, such as microfocused ultrasound, or biostimulators like calcium hydroxyapetite or polycaprolactone. Biostimulator with filling effect provides impressive skin tightening and certain degree of volume restoration and should be considered as one of the ideal modalities for facial rejuvenation.

LIM Ting Song 201ABC (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 13:00 Session: BEYOND INJECTABLES: WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES TARGET SPECIFIC SANDWICH TECHNIQUE (TSST) : A MORE EFFICIENT WAY TO DELIVER DERMAL FILLERS In recent years, hyaluronic acid (HA) fillers have gained popularity as they offer aesthetic improvements previously only achievable with surgeries, but at lower cost and with limited-to-no recovery time. The current trend in HA filler delivery is mostly relied on multiple point injections, using large volume, aiming for both immediate volume increment and lifting. However, such practice often ignore the short term as well as long term consequences, such as implant diffusion, migration, inflammatory reaction as well as facial contour distortion leading to facial overfilled syndrome. Hence, we propose a novel technique to restore, rejuvenate and enhance the face, using minute amount of HA fillers via minimal entry points. Target specific sandwich technique (TSST) approaches facial rejuvenation by sandwiching very small amount of fillers with different rheological properties at strategic areas, in several different layers of the soft tissues. The authors believe that this technique could achieve satisfactory volume correction devoid of complications.

LIM Ting Song 201ABC (LEVEL 2) Friday, May 10, 2019 - from 14:00 to 15:30 Session: ARTIFICIAL INTELLIGENCE TECHNOLOGY: HUMAN MAESTROS VS AI LIVE DEMONSTRATION 3 We propose a novel technique to restore, rejuvenate and enhance the face, using minute amount of HA fillers via minimal entry points. Target specific sandwich technique (TSST) approaches facial rejuvenation by sandwiching very small amount of fillers with different rheological properties at strategic areas, in several different layers of the soft tissues.

NADELA Rosalina 201ABC (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS FACIAL MARKING FOR BOTULINUM TOXIN Detailed knowledge of functional facial anatomy is essential before any facial neuromodulators are injected. The functional muscles of the upper face include 1. Frontalis 2. Orbicularis oculi 3. Depressor supercilii 4. Procerus and 5. Corrugator supercilii. The midface muscles include 1. Nasalis 2.Levator labii superioris alaeque nasi 3.Levator labii superioris 4.Zygomaticus minor 5. Zygomaticus major 6.Risorius 7.Buccinator and 8.Levator anguli oris. Functional Muscles of the Lower Face include 1. Mentalis 2.Depressor labii inferioris 3.Depressor anguli oris 4.Orbicularis oris and 5. Platysma A short lecture will teach one how to identify the muscles and actions and understand the concepts of levator and depressor muscles. This is followed by a live assessment and facial marking in preparation for botulinum toxin A injections.

NADELA Rosalina 201ABC (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS BOTULINUM TOXIN A: A STEP FROM BEAUTY TO REMEDY The use of neuromodulators to treat dynamic wrinkles is still the most popular cosmetic indication for botulinum toxin A (BoNTA). BoNTA binds primarily to cholinergic nerves that innervate skeletal muscles (ie motor nerves) as well as parasympathetic (cholinergic) nerves and sympathetic (cholinergic) or autonomic nerves that innervate sweat glands. It likewise inhibits the C fiber nociceptive neurons that release the neurotransmitter glutamate and substance P. This may account for its use as treatment for pain disorders and inflammatory diseases. In the recent years, there has been much research into the use of BoNTA for dermatological conditions. The current research and use of neuromodulators for psoriasis, blistering diseases, rosacea, male pattern baldness and depression will be discussed.

RAVICHANDRAN Simon 201ABC (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 13:00 Session: BEYOND INJECTABLES: WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES HOW TO USE HA AND CAOH DERMAL FILLERS TO BEST EFFECT WHEN TREATING THE JAWLINE AND CHIN In order to achieve natural aesthetic outcomes we must address multiple signs of facial ageing in synchrony. Using both hyaluronic acid dermal fillers and biostimulatory fillers will better meet patient expectations than single modality procedures.

SAMIZADEH Souphiyeh 201ABC (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS (LIVE MARKING FOR BOTULINUM TOXIN) Live demonstration session on the use of botulinum toxin A

SAMIZADEH Souphiyeh 201ABC (LEVEL 2) Friday, May 10, 2019 - from 09:00 to 10:30 Session: LATEST UPDATES OF INJECTABLES & PERSPECTIVES FROM MAESTROS BOTULINUM NEUROTOXIN FORMULATIONS: OVERCOMING THE CONFUSION Botulinum toxin A is produced by anaerobic spore-forming bacteria and is used for various therapeutic and cosmetic purposes. Botulinum toxin A injections are the most popular nonsurgical procedure worldwide. Despite an increased demand for botulinum toxin A injections, the clinical pharmacology and differences in formulation of commonly available products are poorly understood. The various products available in the market are unique and vary in terms of units, chemical properties, biological activities, and weight, and are therefore not interchangeable. For safe clinical practice and to achieve optimal results, the practitioners need to understand the clinical issues of potency, conversion ratio, and safety issues (toxin spread and immunogenicity).

TSENG Jonathan Te-Peng 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30

Session: NAIL BRACE WORKSHOP

HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results. TSENG Jonathan Te-Peng 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30 Session: NAIL BRACE WORKSHOP THE PRACTICAL STEPS AND TIPS OF NAIL BRACE Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results.

WANG Chao-Chin 201ABC (LEVEL 2) Friday, May 10, 2019 - from 14:00 to 15:30 Session: ARTIFICIAL INTELLIGENCE TECHNOLOGY: HUMAN MAESTROS VS AI IMPACT AND APPLICATION OF AI TECHNOLOGY IN CURRENT AESTHETIC PRACTICE The audience will be able to learn from the advancement of artificial intelligence in aesthetic field and how the commercially available technology possibly assists in the practice.

WU Jennifer 201D (LEVEL 2) Friday, May 10, 2019 - from 13:30 to 17:30

Session: NAIL BRACE WORKSHOP

HANDS-ON: NAIL BRACE INSTALLATION Nail deformity of the nail plate may cause intractable pain and decrease the quality of life of patients. Different types of nail braces have been introduced which may offer as a simple, safe and inexpensive treatment option that avoids surgery. Usually placement of nail brace requires no anesthetic and no recovery period. Braces can be used for prolonged periods of times. It leaves no cosmetic disfigurement, and leads to excellent therapeutic results.

ZABNENKOVA Olga 201ABC (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 13:00 Session: BEYOND INJECTABLES: WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES « TETE A TETE » TECHNIQUE FOR PERIORAL REJUVENATION Lips are one of the most attractive and variable features of a face. The shape and size of the lips are influenced by genetic factors that determine shape and volume of the lips, as well as shape of the jaws and dental occlusion. They are also influenced by individual factors, such as muscle activity patterns, bad habits, dental arch integrity, etc. Lip contouring is done for restoration and beautification of lip contour and volume as well as of the whole perioral area (barcode lines, marionette lines, nasolabial folds). Correction techniques can differ significantly. Each patient needs an individual approach. There are special approach in case of orthocheilia, microcheilia, narrow or asymmetrical lips. To correct lip aging (involution), when not only volume loss, but barcode lines and marionette lines have to be treated, we recommend to combine BoTN with HA fillers, mesothreads, Fraxel and/or other methods.

ZABNENKOVA Olga 201ABC (LEVEL 2) Friday, May 10, 2019 - from 11:00 to 13:00 Session: BEYOND INJECTABLES: WHAT IS THE OPTIMAL PRACTICE FOR DIFFICULT CASES 5 TECHNOLOGIES FOR PRECISE JAWLINE: BOTNA, THREADS, FILLERS, MESOTHERAPY Correction of facial oval is the most common request that patients turn to doctors of aesthetic medicine. Obvious changes in bone structures and soft tissues lead to deformation of the face oval and the appearance of prejawl sulcus In some patients, the most pronounced changes are observed in the mandibula: the rotation of the chin, changes in the angle of mandibula. In other cases the hypertonus of platysma muscle causes the deformation of the jawl. All this changes and as also volume loss in the middle face are the main reasons of ptosis of the face. That is why the correction of the oval of the face consists of several stages, allowing to influence-to correct age-related changes In the case of heavy and obese face mesotherapy with lipolytics can be the first stage of the treatment. We can choose different type of lipolytics as phosphotidylcholine or biomimetic peptides. All them can efficiently reduce local fat deposits and improve the condition of the facial oval. Further correction includes augmentation of the midface, chin and an mandibular angle. And for ultimate results we can recommend meso-threads, to create the frame of the face and additionally have a "lipolytic" effect. In the case of a tired face, with platysma hypertension, the first stage of correction should be BoTN injections to reduce the muscle activity and create precise jawline As the final stage, to maintain the achieved result, we can apply procedures for the restoration and strengthening of the dermis and retinaculum cutis

ZABNENKOVA Olga 201ABC (LEVEL 2) Friday, May 10, 2019 - from 14:00 to 15:30 Session: ARTIFICIAL INTELLIGENCE TECHNOLOGY: HUMAN MAESTROS VS AI LIVE DEMONSTRATION 1 Correction of facial oval: young versus elderly patients . Is there any challengies To improve there face oval - that is the main what mature patients are looking for. Anyway nowdays even young patients often ask for face reshape - to recreate, restore a beautiful zygomatic area and precise jawline line. We may not agree with this, but there is a specific trend for a certain type of the face nowdays especially when we deal with young patients. Most of them ask to improve the cheeks, chin, and mandibulla angle. Correction of the zygomatic area, as a rule, does not present any callengies. While deep injections for mandibullar angle improvement can cause hypertonus of masseter muscle (bruxism). And it is very important to respect the proportions so that the emphasis on a clear oval does not lead to a muscular face Chin correction via needle seems quite save procedure, anyway we observe two cases of art. mentalis centralis embolisation. So that's why we have to change our preferences of entry points and technology of injections

While treating mature patients on one hand we should observe the type of aging (tyed, heavy) on the other - keep in mind individual bone structures, fat compartments expression, the tonus of the muscle (m.masseter, DAO, platysma) and skin quality. All this would help to creat the individual treatment plan (fillers, BoTN, HiFU, thread lifting) for mature patient Abstracts Main Sessions ABSTRACTS MAIN SESSIONS

ASHOUR Mahran 102 (LEVEL 1) Saturday, May 11, 2019 - from 17:30 to 18:00 Session: PATIENT MANAGEMENT HOW TO HANDLE UNHAPPY PATIENTS Audience: Medical professionals.

Method: Oral presentation - Powerpoint; earpiece and microphone for interactivity with audience and my assistant.

Knowledge: Practical advice.

Understand: Customer experience techniques.

Apply: Key considerations for the successful implementation and adoption of steps to turning a negative situation into a marketing opportunity.

Evaluate:- Correct training and implementation of customer experience techniques to achieve a remarkable outcome!

Background: Dealing with unhappy and unsatisfied patients is a challenge we have to deal with as part of our roles. If we know what to say and, more importantly, how to say it, we may be able to save the situation. Here we won't only save the situation, but in fact we can change this to a powerful marketing tool and better relationship with those patients.

Results: Turn disappointment into hope, discomfort into trust, and you can gain back the trust of the patient. You can create a new and powerful word of mouth source, and make sure that this patient will get you 10 patients! Do your best to prevent your customer leaving your practise for whatever reasons.

Conclusion: Once you are aware that your client is unhappy then your first priority is to put yourself into a customer service mind-set and it is important to handle difficult customers professionally. Learning how to stay calm and how to stay cool under pressure can help you get through challenging situations with grace and professionalism! Not all patients will be vocal with their dissatisfaction or ideas for improvement. Indeed, most patients will leave silently. However, being able to determine which patients are unhappy and find out why is powerful information, so you need to be grateful to those who speak and share their anger, for you to be able to solve their issues and develop your practice.

ASHOUR Mahran 101A (LEVEL 1) Sunday, May 12, 2019 - from 17:30 to 18:00 Session: PRACTICE MARKETING DIGITAL AS A POWERFUL MARKETING TOOL FOR DOCTORS AND CLINICS Audience: Medical professionals.

Method: Oral presentation - Powerpoint; earpiece and microphone for interactivity with audience and my assistant.

Knowledge: Digital marketing.

Understand: The power of your digital presence in the customer experience journey.

Apply: Technical and visual updates to your digital strategy.

Evaluate:- Assess the correct platforms for your business, the importance of social listening, analytics and SEO.

Background: With the implosion of information online we are bombarded with, it is important to build your brand online. But where to start? Being online and posting for the sake of pushing out content is not enough without the correct strategy.

Results: The importance of a full LinkedIn profile; uniform branding across your digital platforms and your accessibility and transparency online.

Conclusion: Giving your patients the best customer experience encourages loyalty and accelerates business development. Having a fully searchable website, with linked SEO and social media platforms is an essential part of giving your patients excellent customer experience and generating leads.

AVERINA Vladlena 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? COSMECEUTICALS: DO WE NEED HOME PEELS? Depending on age, environment, life style the expressions of aging signs should be treated by different schemes of anti-age correction from short to long-term treatment. In many cases is very difficult to obtain good result of rejuvenation using only one of therapeutical method of treatment. But combine treatment in clinic (skin needling, peelings, mesotherapy, fillers) and home care give the results that in some cases can compare with surgery. Home pells are very efficient tools at patient's everyday care. How to prescribe it properly? Glycolic acid is number one in home care with peeling effect. But not only. Complimentary treatment and tandem doctor+patient will give perfect result.

AVERINA Vladlena PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: MALE VS FEMALE: BEAUTIFICATION BETWEEN MALE AND FEMALE IN 21ST CENTURY ( LIVE SHOW) THE MAIN DIFFERENCES IN MALE VS FEMALE CORRECTION Gender differences in each next generation became less and less prominent. Generation Z has unisex trend. But we should know the main differences. Male correction should correlate with masculine appearance: Horizontal zigoma Straight eyebrow line Pronounced brow edge Angular mandubular line Prominent chin Sharp lines For female beautification important to stay with: Diagonal zigoma line V-shape eyebrows Curved forehead Oval face shape Sensitive lips Soft and delicate lines Proportions, age, ethnic features, gender differences should be taken in account for the best result in beautification and anti-aging

AVERINA Vladlena 201EF (LEVEL 2) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: ART & SCIENCE FOR THREAD-LIFTS (II): THREADS IN COMBINATION TREATMENT THREADS IN COMBINED NECK TREATMENT Abundant knowledge of anatomy and physiology is a crucial point for performing all aesthetic procedures. It's not only gives us a good and natural result but also prevent possible complications. Also it helps us to understand the mechanism of tissue deformation and ways of appropriate restoration. Threads have occupied a special niche in complex correction of age-related changes. In this work we tried to combine the most effective methods of correction with different threads - from superficial to deep ones. Depending on anatomical features (ptosis and hypertrophy /hypotrophy of fat pads), the prevalence of photoaging or hormonal aging, skin type etc we use therapeutical or surgical threads for different layers. Conclusion Based on anatomical knowledge and practical experience we offer special methods of correction for each clinical case Signs of aging can be managed by combination of mini-invasive techniques in which threads play important role and potentiate good clinical effect and satisfactory results for patients.

BANERJEE Antara 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING WNT SIGNALING: A PRINCIPAL REGULATORY PATHWAY IN CONTROLLING AGING PROCESS IN HUMAN Wnt Signaling: a principal regulatory pathway in controlling aging process in human Dr. Antara Banerjee* Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Kelambakkam, India 603103 E-mail addresses: [email protected]; [email protected]. Telephone: +91-9566072596; +91-7401790276. Office: +91-44-47429050 Abstract: Wnt signaling is a prime and distinctly conserved developmental pathway that synchronizes a broad range of cellular functions through development and adulthood. In the adulthood, deregulation of Wnt signaling has been involved in various age-related diseases. Up-regulation of Wnt signaling is involved in the positive effects of exercise, resulting in the activation of neurogenesis in adult neuronal tissue and myogenesis in mature skeletal muscle. Although the role of Wnt ligands during the development is well studied, very little is known about the plausible actions of Wnt signaling in natural aging. Understanding this aspect of Wnt signaling, can potentially aid in applying this knowledge to develop therapies for anti-aging and to impede the manifestation of many age-related diseases. We recently found that modulation of Wnt through small molecules leads to prolong survival and proliferation of stem cells and positive modulation of ß-Galactosidase activity, ABTS radical scavenging, DPPH Radical scavenging, Nitric oxide, Lipid Peroxidation, Superoxide dismutase activities, Elastase, collagenase and telomerase activities were found. Hence, targeting Wnt pathway may be a potential approach towards finding novel therapies to retard the rate of aging or treat aging related disorders.

CALDERHEAD R. Glen 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES THE ROLE OF 830 NM LED LOW LEVEL LIGHT THERAPY FOR FEMALE PATTERN BALDNESS: HOPE OR HYPE? Background: Female pattern hair loss, or androgenic alopoecia (AGA), is troubling for both the pa-tient and the aesthetic surgeon faced with the problem. Women tend to be somewhat devastated by their hair loss, more so than men, and it is small comfort that thinning due to AGA is reportedly less-prevalent in females than males although the incidence of AGA itself is approximately the same for both genders. The pattern in females is clear with an early age of onset, greatest thinning seen in the frontal and parietal scalp but with retention of the frontal hairline, and with the highest hair density retained in the occipital scalp. Role of dihydrotestosterone: The thinning of the hair is due to the action of androgens in susceptible females, whereby dihydrotestosterone (DHT) binds to the androgen receptors and the genes responsible for gradual miniaturization of hair follicle are turned on. Emergence of LLLT for AGA: Currently, the only FDA approved treatment for female pattern hair loss is minoxidil. Following a number of publications in respected journals showing significant efficacy for LLLT in the treatment of both male and female AGA, an LLLT-based hair comb has also received FDA approval, so I believe that the "hype' part of the title has been addressed, and the "hope' part stressed. LLLT encourages Wnt/ß-catenin signalling: It is possible that LLLT can have an inhibitory effect either on the presence of DHT itself, or on its binding with the androgen receptors which start the thinning process. This latter action interferes with the canonical Wnt/ß-catenin signalling which is known to have a positive effect on mammalian hair growth through action on multipotent epidermal stem cells in the bulge region of the hair follicle which positively influence hair follicle regeneration in telogen to anagen transformation. In some animal studies it was shown that LLLT stimulated hair growth in AGA animal models through upregulation of the expression of both Wnt10b and ß-catenin, the expression of which was both downregulated in the control group compared with normal animals. It was suggested that this counteracted the action of the DHT. In addition, it has been well-recognized that LLLT has a positive effect on local blood flow, including the supply to the papillae. Conclusions: There may be other modes of action which remain to be elucidated, but what has been proved is that LLLT can promote hair regrowth by inducing the anagen phase of hair follicles via strengthening the Wnt10b/ß-catenin pathway, possibly thereby replacing the miniaturized follicles responsible for the this hair growth in AGA with normal ones. I believe that hope wins over hype in the use of LLLT for female AGA. CALDERHEAD R. Glen 101A (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS 830 NM LED-LLLT ACCELERATES WOUND HEALING IN HUMAN SUBJECTS: A FULLY RANDOMIZED, DOUBLE BLINDED AND CONTROLLED TRIAL IN A STANDARDIZED WOUND Background and Aims Low level light therapy with light-emitting diodes (LED-LLLT) has been reported to enhance wound healing, but very few few randomised controlled and double-blinded trials with large patient populations exist in human subjects, and none in a standardised wound. The present study was designed to assess the results of such a trial. Subjects and Methods Seventy-four anonymized subjects from 2 separate sites were enrolled in the study and randomly assigned to the Treatment or Control groups. The fully standardised donor site for thin split-thickness skin grafts served as the wound, and were treated in a double-blinded manner with real or sham 830 nm LED-LLLT. Wound healing was timed, and assessed with daily gross visualization and clinical photography. The pain score at the donor site was also assessed on a visual analogue scale. Results The per protocol group finally comprised 57 subjects. The healing time in the Treatment group was significantly faster than in the Control group (10.28±1.63 vs 11.38±2.17 days, p Conclusions This strictly controlled, randomized and double-blinded trial for the first time in a fully standardised wound model in human subjects showed that 830 nm LED-LLLT could safely and effectively accelerate wound healing, with a potential saving in total population hospital days of around 120 days. This study has quality of life implications for patients and financial benefits for institutions.

CALDERHEAD R. Glen 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES COMBINED FRACTIONAL MICRONEEDLING RADIOFREQUENCY AND THULIUM LASER TREATMENT OFFERS SYNERGISTIC SKIN REJUVENATION Background and Aims: Facial rejuvenation has become an increasingly patient-driven procedure with speedy but significant results and minimal downtime being the holy grail of both patient and practitioners. Fractional tech-niques with both laser and radiofrequency sources have attracted attention with some good results, but still with some downtime. Combination therapy could offer the best points of the separate techniques to give synergistic results with minimal downtime. A pilot mini-study investigated the safety and efficacy of facial rejuvenation with a combination of microneedling fractional radiofrequency (MFR) and fractional minimally-invasive thulium laser (FTL) treatment. Subjects and Methods: Four Korean females, ages from 53-63 yr (mean age 58.25), Fitzpatrick skin type III-IV with mild to moderate photoaging-related sequelae participated in the study. On the first pass an MFR system was used with insulated microneedles to deliver a single pass of RF energy to a depth of 1.5 mm - 1 mm in the dermis (7.5 W, 30 ms exposure). This was immediately followed by an FTL (5 W, 10 mJ) with 2-3 passes over the whole face, and a further 4-5 passes over the target wrinkles. This was repeated for 6 treatment sessions with 2-weekly intervals, and with a follow-up of 16 weeks after the final session. An analytical digital clinical imaging system captured gross and analytical images, and an independently-scored Physician Global Assessment (PGA) scale was used to assess efficacy in addition to patient satisfaction. Results Apparent smoothing of wrinkles and general improvement in skin condition was seen following the 3rd to 4th sessions. At the 16-week assessment very clear improvement was seen both with the naked eye and with specific analytical software from the imaging system. The total mean PGA score was 3.35 (out of 4), and all patients were extremely satisfied with the results. No adverse events were reported and pain was minimal. Conclusions The combination of MFR and FTL was safe and effective, and produced synergistic results in skin rejuvenation in the Asian skin type which were judged to be better than either system used on its own. Further larger population, split-face and controlled trials are warranted to confirm these optimistic results.

CALDERHEAD R. Glen 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES MICRONEEDLE RADIOFREQUENCY FOR DIFFICULT CONDITIONS: STRIAE DISTENSAE, HYPERHIDROSIS AND HIDRADENITIS SUPPURATIVA Background: The development of fractional radiofrequency delivered through the epidermis into the dermis using insulated microneedles, fractional microneedling radiofrequency (MNRF), introduced an interesting new modality for skin rejuvenation, the treatment of skin laxity in the face, jowls and neck and revision of both hypertrophic and atrophic scars. Given that the principle of the technique depends on achieving discrete and controlled layers of coagulation at depths in the dermis from around 0.5 mm to 3.5 mm under a comparatively unharmed epidermis, applications are being developed for MNRF beyond skin laxity and scar revision, for which this "bottom-up" approach would be appropriate. Three conditions come to mind for which MNFR might be beneficial: striae distensae of various aetiologies, hidradenitis suppurativa (HS) and axillary hyperhidrosis (AHH). MNRF for striae distensae: Striae are not to be confused with scar formation: the pathology is different. Striae are the result of sudden expansion and stretching of the skin caused by such growth-related events as pregnancy, normal but sudden growth in puberty and obesity, so that the usual protective functions of the extracellular matrix fibres are overwhelmed, namely collagen fibres as providing the shear strength of the skin, and elastic fibres as giving skin the ability to reform after being deformed. This results in a tearing or shearing of the ECM causing a void, which is filled with fibrotic collagen. In the mid-reticular dermis, breakage and retraction of elastic fibers can be seen, In the epidermis, shiny stretch marks, the actual striae, appear which mostly follow the lines of tension of the tissue. MNRF has strong potential to treat stretch marks because of the delivered damage in the ECM with mechanical microneedling f the epidermis to help to deal with the striae. A fair body of work has been done on MNRF treatment for stretch marks with good results. Potential of MNRF for hidradenitis suppurativa: HS has three phases: the active phase which starts out as painful reddish lumps in the skin, especially in the groin, axillae and breasts, that progress to pus-filled lumps and finally end up as scarring. No recorded study has been done on HS with MNFR, but he potential for treatment in all its phases is good: MNRF has shown good results with severe active acne, which resembles the second stage of HS, and has also been shown very effective for scar revision for the final stage. Good studies are required to assess the potential of fractional MNRF, as there is currently no single effective treatment for what can be a debilitating and embarrassing disease. MNRF for axillar hyperhidrosis: Finally, AHH presents challenges with a variety of nonsurgical and surgical approaches, such as antiperspirants for the former and sympathectomies or laser-assisted lipolysis for the latter. Results however remain at best mixed, and the side effects from the surgical approaches can be severe. The goal is to destroy the sweat glands deep in the axilla wit minimal scarring in the overlying ECM and epidermis. The 3.5 mm depth reached by some MNFR systems attracted attention for its potential to achieve this. The sweat glands can be coagulated and eradicated with several passes usually in the one session, and some compelling studies have shown excellent follow-up results at 6 months post-treatment. Conclusions: In conclusion, whereas studies exist on the efficacy of MNRF for HS and AHH, HS remains at present a potential indication. However, the theory of the treatment of all 3 stages of HS, based on current studies with MNRF for active acne and acne scarring, gives some promise for future efficacy.

CHAN Tom 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS ASIAN ATOPIC DERMATITIS VS. EUROPEAN ATOPIC DERMATITIS Atopic dermatitis (AD) is a disease of distinct Th2-centered inflammation. With the advances in translational studies and personalized medicine, the characterization of AD in different populations has become more and more important. Apart from Th2 inflammation as a shared common component in AD pathogenesis, distinct differences are obvious in various ethnic groups. East Asian patients (from data including Chinese, Japanese, and Korean cohorts) showed different phenotypic characteristics comparing to European patients. Asian AD possesses co-activation of Th17 axis with a way higher extrinsic AD percentage. Extensive molecular and cellular profiling of AD helped differentiate Asian populations from European counterparts. Albeit Th2 inflammation in AD is universal, treatment targets are not. These differences in molecular profiling highlight the existence of diverse optimal treatments for AD sub-populations and sub-groups.

CHANG Shyue-Luen 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 08:30 to 10:30 Session: UPDATES IN MOLECULAR DIAGNOSIS AND NON-INVASIVE SKIN DIAGNOSTIC TOOLS EVALUATION OF SUPERFICIAL LEG VEINS AND ESSENTIAL OF VENOUS ULTRASOUND Imaging modalities for evaluation of venous insufficiency include conventional venography, cross-sectional venography (CTV/MRV), and duplex ultrasound. Among them, duplex ultrasound imaging is the most important advance in the field of phlebology. Duplex ultrasound is a highly operator-dependent imaging modality. The accuracy depends on the person who performs the scan. Success in varicose vein treatment relies on the quality of the ultrasound imaging in pre-procedural evaluation, during procedure, and post-procedural assessment. Understanding ultrasound instrumentation, proper techniques, and diagnostic protocols are essential for evaluation of venous insufficiency. CHANG Shyue-Luen 201EF (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: UPDATES IN VASCULAR TREATMENT COMPLICATIONS IN VARICOSE VEIN TREATMENT As life expectancy increased over the last few decades, more and more people have been impacted by varicose veins, resulting in an increased demand for treatment and prevention. Although complications in varicose vein treatment are not common, minor complications such as skin damage, hematomas, injury of cutaneous nerves, hyperpigmentation or postoperative edemas are reported. Major complications, like injuries to the femoral vein and arteries, deep vein thrombosis, heat- or foam-induced thrombus extension, pulmonary embolism, and stroke are rare but serious with the potential for a fatal event. Keeping these possible complications in mind with knowledge of vascular anatomy and procedure techniques are mandatory for varicose vein treatment.

CHANG Shyue-Luen 201EF (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: UPDATES IN VASCULAR TREATMENT THERMAL AND NON-THERMAL ABLATION IN VARICOSE VEIN TREATMENT Varicose veins are common in the general population. Varicose veins are not only cosmetic concerns but may significantly impact patients' quality of life and cause considerable morbidity such as chronic pain, disability, and leg ulcer. They also have potential associations with other health-threatening diseases, such as deep venous thrombosis, pulmonary embolism, and peripheral arterial disease. There are choices of treatment methods for varicose veins. Options include the following: compression stockings, open venous surgery, sclerotherapy and endovascular procedures (thermal and non-thermal ablation). Among them, the endovascular procedures have the advantages of effectiveness, minimally invasive, and less complications. It is likely that the use of endovascular procedures will continue to increase rapidly because it was recommended by evidence based guidelines as the preferred treatment for patients with varicose veins. In this presentation, we will review the thermal and non-thermal ablation in varicose vein treatment in Taiwan.

CHAO Sheau-Chiou 101A (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:30 Session: TOP CLINICAL CASES: INTERACTIVE DISCUSSION SKIN INFLAMMATORY AND NEOPLASTIC DISORDERS A 75 year-old male patient presented with rapid growing asymptomatic nodules and plaques over face for 2 months. He had received right mandible plastic surgery and soft tissue grafting 30 years ago. A 76 year-old female patient presented with frrm and indurated plques with pus draining sinuses, focl erythema and scarring over both sides of the forehead for 1-2 years. The pre and post treatment photos will be presented.

CHAO Sheau-Chiou 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (LECTURES IN MANDARIN) DIAGNOSTIC CLUE TO GENODERMATOSES Genodermatoses are multisystem disorders with cutaneous involvement. Many of the genodermatoses present with hair, tooth, nail and facial morphology changes and some of these may be the clinical pointers to the diagnosis. Diagnostic clues to various genodermatoses will be discussed.

CHAUCHARD Claude 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES HAIR LOSS: HOW TO READ THE HORMONAL PROFILE TO UNDERSTAND THE MECHANISM AND FUTURE TREATMENT TO STOP THE PROCESS AND HELP HAIR REGROWING We always thinking hair loss is due to high testosterone level in fact this is another male hormone who induce hair loss let me explain u today how to handle properly the hormone replacement and help hair regrowing

CHAUCHARD Claude 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING HORMONAL REPLACEMENT IN MALE MENOPAUSE Andropause refers to the biological changes that men in mid-life experience; some like to compare this state with the female menopause. These changes are not universal and males continue to reproduce well into their old age.

During Andropause, the levels of the hormones testosterone and dehydroepiandrosterone are diminished. As a consequence of this drop, the individual may experience -loss of concentration, low energy levels, fatigue, change in attitude, depression, low libido, and mood swings. Even healthy males experience these symptoms. It is not clear if hereditary factors, enviornment or lifestyle are associated with andropause

However, as a result of disease, subtle changes in the function of the testes may occur as early as 40 to 45 years of age, and more dramatically after the age of 70 in some men. Andropause was an "under diagnosed' and "under treated' health condition. Today there is a lot of improvement in understanding and managing this condition. Simple blood tests diagnose this disorder. Treatment is carried out through Hormone Replacement Therapy (HRT) with fantastic results. Let me explain how to handle a safe andropause approach to change the life of your beloved patients.

CHAUCHARD Claude 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING THE TWO METABOLICALLY SECRETS FOR LOSING WEIGHT WHERE YOU NEED AND NEVER FEEL HUNGRY I have been working for so many years in slimming and always want to change the metabolism of my patients in order they lose weight. Never feel hungry, and where they need on the body. I finally have found the two metabolic secret who govern and allow this process. Secret one: why are we gaining weight? What activate the lipogenesis beside some hormones? Secret two: How can I burn my fat where they are located on my body? It means how can I activate the lipogenesis. And in conclusion today can we say that we are able to change the metabolism of people and shutdown insulin resistance. I will say yes, this is possible, this is my topic of today.

CHEN Peter Ruei-Feng 101A (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS THE BOUNDARY BETWEEN NON-SURGICAL AND SURGICAL INTERVENTION ON LOWER FACE CONTOURING? A Square face is considered unattractive in Orientals, therefore it is a common reason for female patients to have Botulinum toxin as well as contouring surgery. Botulinum toxin is more acceptable for patients than contouring surgery because of the down time. However, the result of toxin is limited in certain cases and patient select is very important.

Reductive mandibularoplasty is a common surgery in Asia for prominent mandibular body and angle. In certain cases, 2D images such as lateral cephalometric and panoramic radiography are efficient for surgical planning. However, it's difficult to evaluate the 3D contour of the mandible with 2D images. The rapid developing of 3D imaging technology and the subsequent development of computer-assisted simulation has dramatically changed the craniofacial surgeon's perspective in the last two decades. It facilitates diagnosis, measurement, as well as surgical planning in this field. Collaboration of 3D photo and Computed tomography in simulation offers surgeon a easy way to communicate with patients.

The purpose of the present report is to describe our indications and methods of using computer-assisted simulation software in facial contouring surgeries. Calibration of natural head position, design of osteotomy line, measurement the nerve route and evaluation of symmetry will be emphasized with case presentations. Post-operative computed tomography is superimposed to simulation image to evaluate the accuracy. The author believes that computer-assisted simulation system is efficient for planning of mandibularoplasty and prediction of surgical outcome.

CHEN Peter Ruei-Feng PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: SHOWCASE OF INJECTABLES: LOWER FACE & NECK IMPROVEMENT OF PERIORAL AESTHETICS WITH ORTHOGNATHIC SURGERY Perioral region is an unique characteristic of the face. There is strong relation between the perioral soft tissues and the underlying dentition and jaw bones. Disproportion of maxilla and mandible may result in aesthetic and functional considerations, such as bimaxillary protusion, protruded lip, gummy smile, lip incompetence, mentalis strain and malocclusion. Cephalometric analysis and surgical planning provide simple but limited information as facial morphology changes after two-jaw surgeries are dynamic and three-dimensional. Treatment strategies, such as extraction or not, whole piece setback or segmental osteotomy, pre-surgical orthodontic or surgery-first, are usually controversial in difficult cases. Computer-assisted Simulation system ( CASS ) is applied for orthognathic surgery for years. Compared to two-dimensional surgical planning, CASS provides precise three-dimensional structure of maxilla and mandible, offers free movement of complex and predicts collision of bony contact. Different treatment plans ( ex. Segmental osteotomy or whole piece movement ) can be establish before surgery and allowed surgeons to discuss with patients. Meticulous planning and execution of the osteotomies in accordance with the simulation are essential for optimal aesthetic and functional outcomes

CHEN Kai-Lung 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: DRUG REACTION (DRUG ALLERGY & CANCER TREATMENT-RELATED SKIN REACTION) SKIN TOXICITIES RELATED TO EGFR INHIBITOR TREATMENTS Over expression of epidermal growth factor receptor (EGFR) is noticed in many different types of cancers, including lung cancer, breast cancer, colorectal cancer, etc. In those patients harboring mutations in EGFRgene, treatments targeting on EGFR signaling pathway provide good clinical responses. However, adverse effects, including skin toxicities, due to EGFR inhibition agents might lead to poor drug adherence or discontinue the usages of these agents. Therefore, prevention, early detection and management of these skin toxicities have a critical role in reducing patients' discomforts, improving patients' quality of life, maintaining usage of these agents, and further having a better prognosis.

CHEN Chun-Bing 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: DRUG REACTION (DRUG ALLERGY & CANCER TREATMENT-RELATED SKIN REACTION) IMMUNE-RELATED ADVERSE SKIN REACTIONS INDUCED BY ANTICANCER IMMUNE CHECKPOINT BLOCKADE Skin toxicities are the most common and usually the earliest-onset immune-related adverse events (irAE), consisting mainly of vitiligo, pruritus, maculopapular rash, eczematous dermatitis, lichenoid dermatitis, delayed type hypersensitivity, and bullous disorders. With all irAEs, maculopapular rash predominates. Lichenoid rashes can affect the skin as well as the . Pruritus presents with or without rash and significantly compromises health-related quality of life for patients because of its resistance to traditional antipruritic therapy. Low-grade toxicity (grade 1 or 2) usually requires moderate- to high-potency topical corticosteroids and supportive care. Systemic corticosteroids and treatment delay would be warranted for grade 3 events, any grade of bullous disorders, rash with mucosal involvement, or life-threatening cutaneous reactions (for example, Stevens-Johnson Syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms). Prompt awareness of the life-threatening Stevens-Johnson syndrome/toxic epidermal necrolysis condition is essential and rechallenge with immune checkpoint blockade is suggested to be prohibited due to potential fatal toxicity. CHEN Yi-Ju 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: PSORIASIS GUT MICROBIOTA IN PSORIASIS Microbiota has been proposed to contribute to host nutrition and to the development or maintenance of a robust immune system. The disturbance of microbiome homeostasis, known as dysbiosis, may trigger several immune disorders through the activity of T cells and lead to an inflammatory process. Dysbiosis, especially in the gut, has been linked to obesity, metabolic syndrome, diabetes, malignancy, as well as autoimmune diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), inflammatory bowel disease (IBD), multiple sclerosis, and Bechet's disease. The presence of certain bacteria, such as Clostridium and segmented filamentous bacteria (SFB) might augment arthritis via increasing gut mucosal permeability, decreasing regulatory T cells and subsequently inducing local and systemic Th17 inflammation. A complex relationship between psoriasis and multiple comorbidities including cardiovascular diseases, metabolic syndrome, depression, autoimmune diseases and malignancies, has been widely explored. Recently, broad-spectrum antibiotics treatment was reported to reduce the phenotypic skin thickness and decrease the percentage of γδT cells and Th17 cells and subsequent IL-17 production by using the imiquimod (IMQ)-induced inflammation mice model. The results suggested a correlation between alterations of intestinal microbiota and Th17 inflammation. An alteration of gut microbiota has also been reported in psoriasis patients. The clinical relevance of altered microbiota in psoriasis remains to be clarified. In this study, we investigated the intestinal microbiota and metabolic gene functions (predicted from microbial composition) between psoriasis patients and non-psoriasis controls. The covariates of demographic factors including diet, smoking and alcohol habit, disease activity, presence of arthritis, comorbidities and treatment modalities were also evaluated.

CHEN Yi-Ju 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: PHOTOMEDICINE LONG TERM UVB PHOTOTHERAPY AND SKIN CANCER RISK Narrow-band ultraviolet B (NB-UVB) phototherapy is a widely used treatment for various dermatoses. The risk of skin cancer following long term NB-UVB phototherapy has rarely been explored in skin phototypes III-V.We conducted a nationwide matched cohort study and identified a total of 22,891 psoriasis patients starting NB-UVB phototherapy from the Taiwan National Health Insurance Database during the period 2000-2013.There were no significant differences in the overall cumulative incidences of skin cancers between the two cohorts (log-rank t test, P = 0.691) during the follow-up periods. The short term UVB treated-cohort had a significantly lower prevalence of actinic keratosis when compared with the Long term UVB-cohort (0.54% versus 1.00%, P=0.005).

CHEN Yi-Ju 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (LECTURES IN MANDARIN) MICROBIOME IN DERMATOLOGY: NOW AND THE FUTURE Microbiota has been proposed to contribute to host nutrition and to the development or maintenance of a robust immune system. The disturbance of microbiome homeostasis, known as dysbiosis, may trigger several immune disorders through the activity of T cells and lead to an inflammatory process. Cutaneous and gut dysbiosis have been linked to several chronic inflammatory diseases, including atopic dermatitis, psoriasis and rosacea. The altered microbiota in these diseases might be associated with a complex relationship with multiple comorbidities, including obesity, metabolic syndrome, depression, autoimmune diseases and malignancies. Recently, manipulation of cutaneous or gut microbiota has provided promising therapeutic modalities to these skin diseases.

CHEN Leslie Yen-Peng PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: SHOWCASE OF INJECTABLES: LOWER FACE & NECK THE POSIBLITIES OF FACIAL CHANGES FROM ORTHODONTIC TREATMENT From conservative cosmetic injection, orthodontic treatment & orthognathic approaches,there are many ways to improve or modify patient's facial appearance.This concise section will deliver the point of view form contemporary orthodontic treatment.

CHEN Jau-Shiuh 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) SURGICAL TREATMENT OF MELANOMA Surgery remains the primary treatment modality for cutaneous melanoma(CM). To reduce the risk of local recurrence, wider and deeper surgical excision with histologically negative margins is the recommended and first-line treatment for primary CM of any thickness, as well as for melanoma in situ. Surgical margins should be based on tumor thickness. For invasive CM, it should be ≥1 cm and ≤2 cm measured clinically around the primary tumor. Depth of excision is recommended to the fascia. SLNB should be considered in appropriate patients with CM >1 mm thickness (≥T2a), but not recommended for patients with MIS or for most T1a CM. Immediate completion lymph node dissection increased the rate of regional disease control and improved staging among patients with a positive SLN but did not increase melanoma-specific survival.

CHENG Charles 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS A PROPOSED 3D APPROACH TO SUBMENTAL FAT WITH DEOXYCHOLATE INJECTION The standard injectable approach of 10mg/ml deoxycholate in the submental area has been an evenly distributed grid injections in a two-dimensional fashion with needles. The speaker will propose an alternative approach to submental deoxycholate injection using a microcannula to effectively inject in a three-dimensional fashion in consideration of the shape of the submental fat. In the speaker's own personal clinical experience, this approach offers a clear reduction in the incidence of ecchymosis and pain with comparable or improved efficacy. The approach to dosing and planes of injections will be discussed along with considerations of the submental anatomy.

CHENG Charles 102 (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: PITFALLS TO AVOID IN AESTHETIC PROCEDURES RETROBULBAR HYALURONIDASE INJECTION TO THE RESCUE, MAYBE NOT! : AN IN VITRO MODEL ASSESSING THE PENETRATION OF HYALURONIDASE THROUGH OPTIC NERVE DURA FOR MANAGEMENT OF HYALURONIC ACID FACIAL FILLER EMBOLISM Retrobulbar hyaluronidase injection has been proposed by some and accepted by many, as a potential method to rescue blindness secondary to central retinal artery HA occlusion. Maybe not! The speaker will describe the soon to be published in-vitro HYAL penetration study of fresh human optic nerves. Background information on the use of retrobulbar hyaluronidase will be discussed along with the details of the research study that demonstrated the unlikelihood of highly concentrated HYAL penetrating through the layers of the optic nerve to reach the lumen of the central retinal artery. The search for a treatment of central retinal artery HA occlusion deserves much more consideration and further research. The speaker will also propose some injection tips that may potentially reduce the risk of CRAO.

CHI Ching-Chi 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: PSORIASIS AUTOIMMUNE COMORBIDITIES IN PSORIATIC DISEASE: A LONG FORGOTTEN DOMAIN Psoriasis is a chronic inflammatory immune-mediated skin disease. Hundreds of epidemiologic studies have emphasized associated inflammatory comorbidities for example cardiovascular disease, renal disease, and uveitis. By contrast, autoimmune comorbidities of psoriasis are not uncommon but often neglected. In this talk I will give an overview of autoimmune comorbidities of psoriasis and present our latest research on associated vitiligo, thyroid diseases, and multiple sclerosis.

CHI Min-Hui 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: PRACTICAL DERMATOSCOPY (LECTURES IN MANDARIN) PRACTICAL DERMOSCOPY BEYOND PIGMENTED LESIONS Dermatoscopy is a noninvasive technique that has been used increasingly by the dermatologists for the diagnosis of pigmented skin tumors. It provides additional information at a submacroscopic level that improves diagnostic accuracy compared to examination with the naked eyes. Through the modified magnifying characteristic of dermatoscopes, we are allowed to visualize the pigmented structures or vessels in the epidermis and superficial dermis. In addition to pigmented skin lesions, dermatoscopy also plays a vital role in the differential diagnosis of non-pigmented skin lesions. Here, we will share the practical experience of dermatoscopy in non-pigmented skin lesions.

CHIU Pin-Chi 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? HOW TO REDUCE ENERGY-BASED DEVICES RISK BY PROPER SKIN CARE REGIMEN Laser light has unique properties that allow it to be used therapeutically. When laser light hits the skin, the absorbed energy is most responsible for the clinical effects(accept or adapt) and its side effects(damage or destruction). The complications resulting from collateral effects are created when energy intended for the target chromophore is nonselectively diffused to and absorbed by surrounding tissues and structures. In this talk, I will introduce the concepts about risk management and reduction while using laser treatments and how to maximize clinical results by proper skin care regimen after laser procedures.

CHIU Pin-Chi 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? COSMECEUTICALS : FACTS BEHIND SCIENCE Cosmeceutical(or dermocosmetic) is the combination of cosmetic and pharmaceutical. Cosmeceuticals are supposed to be cosmetic products with scientifically proved bioactive ingredients purported to have medical or drug-like benefits. They are booming concepts in recent years and many cosmetics in the markets are claiming and advertising such ideas. Although some products are truly designed by such ideals, some are overclaimed and some are misleading to the consumers. Even US Food and Drug Administration (FDA) does not recognize any such category as "cosmeceuticals" and the term has no meaning under the law. However, as a dermatologist, I think cosmeceuticals are existing and still keeping upgrading and progressing. We should learn more knowledge about cosmetic science, toxicology, skin biology, ecobiology and pharmaceuticals to understand more facts behind cosmeceuticals.

CHIU Pin-Chi PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: MALE VS FEMALE: BEAUTIFICATION BETWEEN MALE AND FEMALE IN 21ST CENTURY ( LIVE SHOW) MALE COSMETICS: FASHION OR NECESSITY ? The use of cosmetics especially skin care products and the application of cosmetic procedures for men has been ignored in the past, but they are drawing increasing attention in recent years. As men are changing their habits to learn to use cosmetic products, the dermatologists will be asked for expert advice regarding efficacy and safety of cosmetics for male skin. For this service, dermatologists need to be aware of anatomical and physiological differences between male and female skin, special needs for male skin, regarding oil control, acne prevention, shaving and grooming and consequences of social influence for psychological identity and confidence in their daily life. Male cosmetics are not only trends but also real necessities.

CHIU Pin-Chi 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ACNE AND ROSACEA FORUM HOW TO TREAT ROSACEA BETTER BY HOLISTIC APPROACH Rosacea is a highly prevalent, chronic inflammatory disease, presented with persistent condition in which the skin on a person's cheeks, nose, chin, eyelids, or forehead becomes inflamed and red, often producing small pimples and noticeable blood vessels. The treatment of rosacea remains a challenge to dermatologists. Therapies include medications, IPLs, lasers, cosmeceuticals, nutraceuticals, LLLTs, mesotherapy and various combinations of these modalities. The appropriate treatment depends on clinical types and patient's various clinical symptoms. We generally rely on medical treatments for rosacea. But if we want to achieve better and longer efficacy of disease control, lifestyle change, emotion regulation, diet modification, trigger avoidance and skin care regimen adjustment all play important roles in holistic rosacea management.

CHIU Pin-Chi 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: PRACTICAL DERMATOSCOPY (LECTURES IN MANDARIN) THE EVOLUTION OF DERMOSCOPY: MY JOURNEY Dermoscopy, also known as dermatoscopy or epiluminescence microscopy, is a noninvasive in vivo technique that allows visualization of microstructures of the epidermis, the dermoepidermal junction and the papillary dermis that are invisible to the naked eye. Dermoscopy is an essential part of a dermatologist's toolbox; the technology is consistently improving, while providing a great increase in diagnosis efficacy, workflow, and patient safety. In addition to its clinical benefits, the device itself offers a greater number of applications and features designed to further enhance practices. There are many different models of dermatoscopes in the market. In this talk, I will compare their differences and share my experience for choosing the instruments.

CHIU Hsien-Yi 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: PSORIASIS PREDICTORS OF TIME TO RELAPSE FOLLOWING WITHDRAWAL OF BIOLOGIC THERAPY IN PATIENTS WITH PSORIASIS WHO REACHED REMISSION WHILE ON TREATMENT Data on predictors and time to relapse in psoriasis patients discontinuing therapy after remission are lacking.Our research aimed to investigate incidence, characteristics, and predictors of relapse after withdrawal of ustekinumab in psoriasis patients. Our research screened 500 psoriasis patients who received ustekinumab (669 treatment episodes (TEs)) between 2011 and 2018. Overall, 202 patients (304 TEs), who had responded to therapy and were withdrawn from ustekinumab treatment, were included. The cumulative probabilities of relapse-free at 6 months, 12 months, 18 months, 24 months and 36 months of withdrawal from ustekinumab treatment was 49.3%, 12.6%, 5.3%, 4.7% and 1.6%, respectively. Multivariate regression analyses with a generalized estimating equation showed that after adjustments, biologics-naive, the maximum Psoriasis Area and Severity Index (PASI) improvement on ustekinumab, time to achieve PASI-50 after initiation of ustekinumab, family history of psoriasis, chronic kidney disease, and immunosuppressants use while off ustekinumab were significant predictors of time to relapse following ustekinumab discontinuation. In summary, the results showed treatment response prior to cessation, patient baseline characteristics, and use of immunosuppressants during remission were important predictors of time to relapse while off ustekinumab therapy. Careful assessment of these factors is suggested when considering ustekinumab withdrawal.

CHIU Hsien-Yi 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: WHEN AND HOW TO USE BIOLOGIC AND SMALL MOLECULE THERAPIES (LECTURES IN MANDARIN) SELECTING IDEAL BIOLOGIC TREATMENT FOR PSORIASIS: WHICH THERAPY FOR WHICH PATIENT In the past decades, the biologics have revolutionized our treatment for psoriasis by showing excellent efficacy. Ever since the first biologic for treating psoriasis in was approved in 200 9 in Taiwan, the ability of biologics to clear, or almost clear, cutaneous disease has changed the outcomes and expectations of many patients with psoriasis. However, deciding on what biologic will work best for specific patients is a big unknown and how prescribing clinicians and patients should choose or use among many newly available biologics remains challenging. Although studies investigating this issue are limited, I will discuss factors which possibly influence treatment choice with biologics and published guidelines which made recommendations in this speech.

CHIU Yu-Hsun 101A (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 17:30 Session: FOCUS SESSION ON NOSE BEAUTIFICATION BOUNDARY BETWEEN NON-SURGICAL & SURGICAL NASAL AUGMENTATION (I) Asian rhinoplasty is augmentation rather than reduction. The nasal dorsum is augmented, and the tip definition is enhanced in most cases. We performed surgical rhinoplasty using autologous cartilages with or without alloplastic materials. Medical or injection rhinoplasty is one alternative method for enhancing the shape of Asian nose. The use of fillers in this purpose becomes very popular nowadays because of the improvement of safety and effectiveness. Through this lecture, I would like to discuss about 1. the basic anatomy for my preferred technique 2. the technical details of my method of rhinoplasty 3. the limitation and complication of filler and surgical rhinoplasty

CHO Yung-Tsu 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: URTICARIA AND PRURITUS (LECTURES IN MANDARIN) WHAT'S NEW IN CHRONIC URTICARIA? Chronic urticaria is by no means an easily controlled disease. It affects almost every aspect of patients' life. In addition to drug compliance of patients with chronic urticaria, treating physicians' better understandings of the pathogenesis and treatment modalities are important to deal with the disease. With the increasing evidence to support the use of anti-IgE treatment in managing chronic urticaria, treatment guidelines and consensus have been updated accordingly. In addition, with the increasing usage of anti-IgE treatment and subsequent analytic studies, more and more details of chronic urticaria have been discovered in these years. In this talk, I will discuss the new treatment suggestions of chronic urticaria and also mention the new advances in the pathogenesis of the disease.

CHO Yung-Tsu 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS EMERGING BIOLOGICS IN ATOPIC DERMATITIS Atopic dermatitis is a complex disease and can affect all age groups of patients. Patients with atopic dermatitis usually suffer from relapsing itchy skin eruptions years after years which may cause great impacts on their daily life. Conventional treatments can relieve discomforts and improve quality of life in most of the patients. However, in those of severe diseases, the effects of conventional treatments are usually inadequate. Many factors involve in the pathogenesis of atopic dermatitis, including Th2, Th1, Th17, Th22 cytokines, alarmins, and IgE. These factors are potential therapeutic targets in the management of atopic dermatitis. In this talk, I will present current advances of these emerging biologics in atopic dermatitis and I will also discuss the current weakness and problems of these treatment modalities. With such progress, a new era of atopic dermatitis management is coming in the near future. It is an opportunity and also a challenge for treating physicians. CHRISTIE Andrew R. 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? INFUSION OF ACTIVE SUBSTANCES WITH MICRO-NEEDLING : CREATING PROCEDURAL SAFETY With progressive popularity in aesthetic medicine, automated micro-needling creates thousands of puncture channels into the skin, delivered by small, solid needles. Traditionally used to treat a large variety of aesthetic indications such as atrophic scars and rhytids, microscopic wounds produce a powerful stimulus that initiates regenerative wound healing. More recent innovations however have seen the development of automated micro-needling as a catalyst, above and beyond traditional injections, for the delivery of drugs and active substances into the skin. Whilst micro-needling has often capitalised on the hope of creating dermal infusion of aqueous solutions, recent studies have confirmed that automated micro-needling, in fact serves as a highly effective delivery system with greater infusion potential than topical application or injection techniques with hollow needles. The consequent risk of granulatomous reaction increases substantially when substances of high molecular mass are introduced into the skin. Furthermore, the infusion of topical products into the dermis, risks the facilitation of immunogenic particles whilst increasing the potential of localised hypersensitivity and nodules. Understanding and assessing the molecular weight, formulation and purity of drugs and active substances becomes an essential for patient safety, when undergoing an automated micro-needling procedure. In a safe working environment, the combination therapy of micro-needling with the infusion of active substances, significantly enhances positive patient results. Indications including hyperpigmentation, acne and alopecia may effortlessly be treated on all Fitzpatrick skin types and ethnicities.

CHRISTIE Andrew R. 201EF (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA MICRO-NEEDLING & MELASMA - DELIVERING INNOVATIVE AND EFFECTIVE PATIENT SOLUTIONS Statistically, treatment of unwanted hyperpigmentation is the second most common reason patients seek an aesthetic medical solution. Melasma is a hormone-triggered and ultraviolet radiation activated form of hyperpigmentation that appears as bilateral facial macules. It is argued to be the most challenging type of hyperpigmentation to treat - there is a high risk of the condition becoming worse. As pigment-producing melanocytes are highly sensitive to heat and collateral damage created by keratinocyte thermolysis, micro-needling delivers innovative and successful results, whilst respecting melanocyte integrity. A corrective cascade is activated by the release of regulatory growth factors for fast and impressive outcomes. Treatment with micro-needling is suitable for all Fitzpatrick skin types and ethnicities. Results may be apparent after just two procedures with some studies reporting 100% success rate with positive patient response. Combination therapies with micro-needling, including the infusion of active tyrosinase-inhibiting agents (including some mesotherapy and keratolytic chemical peels), deliver even greater treatment versatility and results. Patient commitment to the daily topical application of pigment-sedatives and a high protection sunscreen enable further long-term management of this chronic, recalcitrant skin condition.

CHU Chia-Yu 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: FROM BENCH TO BEDSIDE (LECTURES IN MANDARIN) WHY DERMATOLOGISTS SHOULD DO BASIC RESEARCH? Basic research in medicine can be defined as research with the purpose of unravelling simple elementary biological facts. It needs not have the purpose of applying the resulting knowledge to a clinical problem. As a matter of fact, in basic research we never know in advance whether there will be any application, or if there is any, when it will come or to what it will apply. Basic research is inconceivable without experimentation because simplification of complicated natural phenomena requires establishment of arbitrarily chosen conditions. All diseases represent disturbances of normal functions. Thorough understanding of the nature of a morbid process is inconceivable without the understanding of the function which is disturbed. We shall not understand seborrhea, acne vulgaris or xerosis of the skin without studying the normal function of sebaceous glands; or, keratinization anomalies without investigating the physiological process of keratinization; or, the role of bacteria in skin diseases without a thorough knowledge of the bacterial flora of normal skin under different conditions; or, the influence of nutritional factors without knowing the effects of excess and deficiency of these factors on normal skin; or, malignant tumors without understanding the factors regulating normal cell division; or, finally, the influence of emotional factors on skin diseases without studying the physiological nerve impulses going from the cerebral cortex to the skin. SID presidential address (Rothman, 1949) Rothman S. Basic research in dermatology. J Invest Dermatol. 1949; 13:165-70. CHU Chia-Yu 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS ATOPIC DERMATITIS GUIDELINE UPDATE Management of atopic dermatitis (AD) must consider the individual clinical variability of the disease. This talk will include review of different guidelines and recommendations for the management of AD. Basic therapy is focused on treatment of disturbed barrier function by hydrating and lubricating topical treatment, besides further avoidance of specific and unspecific provocation factors. Psychosomatic counselling is recommended especially in stress-induced exacerbations. Therapeutic patient education is recommended for children and adult patients. Topical anti-inflammatory treatment based on corticosteroids and calcineurin inhibitors is used for flare management and for proactive therapy for long-term control. Topical corticosteroids remain the mainstay of therapy, whereas tacrolimus and pimecrolimus are preferred in sensitive skin areas and for long-term use. Topical phosphodiesterase inhibitors may be a treatment alternative when available. Adjuvant therapy includes UV irradiation, preferably with UVB 311 nm or UVA1. Pruritus is targeted with the majority of the recommended therapies, but some patients may need additional antipruritic therapy. Systemic immunosuppressive treatments for AD include cyclosporine, methotrexate, azathioprine and mycophenolic acid, especially for severe refractory cases. Biologicals targeting the T helper 2 pathway such as dupilumab may be a safe and effective, disease-modifying alternative when available. Oral drugs such as JAK inhibitors and histamine 4 receptor antagonists are in development. Microbial colonization and superinfection may cause disease exacerbation and can require additional antimicrobial treatment.

CHUANG Celina Ying-Yen 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ACNE AND ROSACEA FORUM PHOTODYNAMIC THERAPY FOR INFLAMMATORY ACNE TREATMENT Photodynamic therapy (PDT) is a modality fo acne treatment by activating molecules that could absorb light, producing single oxygen species, reversibly damages sebaceous cells, and eventually destroying bacteria. Significant levels of photosensitizing porphyrins will accumulate in skin after aminolevuninic acid (ALA) or methylaminolevulinate (MAL) is applied. After topical application of photosensitizer, a build up of PpIX concentration is higher in acne lesions and sebaceous glands than in surrounding tissue. Following light activation of the photosensitizer, a photodynamic reaction that kills the pathogenic bacteria and damages sebaceous glands is induced.

Patients with inflammatory acne is able to achieve significant improvement with three-session treatment course. Topical 20% ALA pulse red light, although effective, with is associated with significant side effects and discomfort. Similar effects can be achieved with lower concentration of ALA, but with much lower risk of side effects. The knowledge of PDT will provide physician another effective treatment modality for acne patients when other treatments have failed or have not offered substantial improvements.

CHUANG Celina Ying-Yen 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ACNE AND ROSACEA FORUM ACNE WITH DEMODICOSIS: CLINICAL OBSERVATION AND MANAGEMENT Despite clinicians usually deny the association between Demodex infestation and acne vulgarism, it has been proved otherwise in some clinical practices. Contradictory conclusions are also reached among scientific publications between their associations. Sebaceous hyperplasia in acne vulgaris may facilitates the development of Demodex mite. While high Demodex confirms a diagnosis of papulopustular rosacea, it does not exclude the presence of another dermatosis. In daily practice, the clinical diagnosis of demodicosis with acne vulgarism is not always straightforward: clinical signs are suggested by non-specific features, such as follicular scales, redness, sensitives skin, pruritus, on top of signs and symptoms of acne vulgaris. Demodicosis, papulopustular rosacea and acne vulgarism may belong to one big disease entity. This indicates that when regular treatments for acne vulgarism are ineffective, examination of Demodex mites and necessary acaricidal therapies should be considered.

CHUNG Wen-Hung 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: FROM BENCH TO BEDSIDE (LECTURES IN MANDARIN) APPLICATION OF WHOLE GENOME SEQUENCING IN CLINICAL PRACTICES Patients with inherited skin diseases are often difficult diagnostic challenges in dermatology. The conventional hunt for the underlying molecular pathology may involve candidate gene screening or linkage analysis. Recent technical advances in DNA sequencing have rapidly facilitated important progress in genomic medicine. Notably, next-generation sequencing (NGS) allows a more comprehensive approach to diagnosing inherited diseases, with potential savings of both time and cost. Since next-generation sequencing introduction into mainstream research in 2009, more and more reports have been published on the use of NGS in genetic disorders, including inherited skin diseases. The presentation highlights the value of whole-exome/genome sequencing, in combination with bioinformatics analysis, in determining the precise molecular pathology and clinical diagnosis in patients with genetic skin disorders. The recent development of NGS makes dermatology exciting a great possibility for discovering genes responsible for variable skin disease, better understanding complex molecular pathways, and eventually developing targeted therapy or disease prevention strategy.

CHUNG Kee Yang 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) RISK FACTORS FOR RECURRENCE IN ASIAN LOCALIZED MELANOMA Although predicting recurrence is important for localized melanoma, there is lack of study for investigating prognostic risk factors of recurrence in localized melanoma in Asian patients, with predominant acral melanomas. This is a retrospective study to find out risk factors of recurrence in localized melanoma in Asian patients. In this retrospective study, cutaneous melanoma patients visited and followed-up for more than 6 months at the department of dermatology in Severance hospital from 2000 to 2018, without evidence of nodal or distant metastasis, were reviewed. A total of 340 patients diagnosed with cutaneous melanoma and staged as melanoma in situ, stage I or II at Severance Hospital were reviewed. Acral melanoma (70.3%, 239/340) was the most predominant subtype. Among them, 92 patients (27.1%) showed recurrence after primary melanoma removal (29 local recurrences, 49 regional metastases and 28 distant metastases). Male sex (p=0.030) and Breslow thickness >1mm (p=0.008) were correlated with increased risk of recurrence. Tumor mitotic rate higher than 4/10HPFs was related with higher distant metastasis (p=0.048). Breslow thickness >2.5mm in males and >4mm in females showed higher predictive value for recurrence compared to traditional stage IIB and IIC. (RR 4.947 vs 3.689, HR 3.743 vs 2.972) In Asian localized cutaneous melanoma, male sex and Breslow thickness are the two most important prognostic factors for recurrence. We also found that different cutoff values in Breslow thickness according to sex (male 2.5mm, female 4mm) may apply for better prognostic predictability in our patients.

CHUNG Kee Yang 101A (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS SURGICAL ANATOMY OF THE EYELIDS AND TECHNIQUES FOR ANTIAGING Eyelids are the most important structures in the cosmetic surgery of the eye. Upper eyelid consists of 4 layers at the tarsus level and 8 layers (7 in Caucasians) in the supra-tarsal orbital septum level. The 4 layers of the tarsus level are skin and subcutaneous fat, orbicularis oculis muscle, tarsus, and conjunctiva. Skin and subcutaneous fat, orbicularis oculis muscle, sub-muscular layer, orbital septum, orbital fat, levator palpebrae superioris, Müller's muscle and conjunctiva constitute the supra-tarsal level. Lots of factors have to considered when performing rejuvenating blepharoplasty. Patient's age, degree of elasticity of the eyelids, appearance of the patient at younger age and overall aging feature of the patient are some of the factors when pre-operative evaluation is being done. Taking these factors into account, lower blepharoplasty can be done by cutaneous approach or conjunctival approach. Lasers with wavelengths that target fat can be used to coagulate the orbital fat in younger individuals instead of doing open surgeries. These lasers can be used to correct for any asymmetry of the orbital fat pads after open surgeries.

D'ALESSIO Patrizia 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING NUTRITION AND COSMECEUTICALS DELAYING SKIN AGING Introduction Bio-molecules contained in food have the capacity to induce important epigenetic shifts in several aging processes, such as the extension of DNA methylation and de-methylation rates. The consequences of metabolic and neuro-immune regulations are particularly visible in the modifications of skin physical and aesthetic qualities, but deeply correspond to a global change in governance of the whole body. Also, based on personalized and precision medicine, nutrition has generated nutrigenomics, surmising that a possible match of individual genetic variables and molecular food components would be possible. Yet, it seems that food intake is even more interesting when it is able to modify or sustain microbiota functions. Still, food not only contains bio-active molecules, but also anti-cancer, immune-stimulating and anti-inflammatory components. Apprehended by medicinal chemistry, these can be introduced as innovative nutraceutics and cosmeceutics acting on the many functions sustaining a radiant and elastic skin. Preclinical and clinical studies The orange-peel-derived terpene d-Limonene, probably through its metabolite, perillyl alcohol (POH), has been reported to have tissue-repair properties. In pre-clinical studies. d-Limonene and POH demonstrate significant anti-inflammatory effects in murine dermal inflammation and wound-healing. The decreased systemic cytokine production, inhibition of endothelial P-selectin expression and neo-vascularization induced by these terpenic compounds contribute to their healing effects on the epidermal barrier. Preliminary results have been obtained in observational studies conducted by administering orange peel extract (OPE) in a number of human conditions, from stretch marks to intermediate psoriasis. Results Besides its medical properties, d-limonene contained in OPE Capsules and Brumes, has been shown to display remarkable rejuvenating properties of the skin. Several human studies have been performed on volunteer women aged between 53 and 69 years old treated with OPE for 29 days administered as a mist prepared using the patented Wpe/Ultradrops® technology. Facial wrinkles were assessed with the Quantirides® software by micro-relief analysis of silicone imprints of predefined crow's foot areas performed with Silflo®. The number, length, mean depth and total surface of wrinkles, before and after treatment, showed a significant decrease of the number, length and surface of wrinkles (p Discussion Acting on nutrition, several goals of a successful anti-aging strategy can be achieved. A number of nutritional interventions are profoundly anti-inflammatory. Curcumin, resveratrol, polyphenols or AISA OPE should be daily companions of a per se balanced diet. The pleomorphic actions of these natural compounds can find applications in such diverse fields as wound repair, psoriasis treatment, and skin cancer cure or prevention. Their active molecules have also well been described for anti-cancer effects. Moreover, the respect of circadian rhythms in food intake induces a fine-tuning between central and peripheral oscillations, guaranteeing an optimum uptake of precious micro-nutrients from food. In conclusion, skin anti-aging treatment plans should involve a constant control of inflammation through nutrition and nutraceutics/psychobiotics/cosmeceutics, composing a new lifestyle.

D'ALESSIO Patrizia 101A (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: REGENERATIVE MEDICINE, CELL THERAPIES & MICROBIOME SKIN AND GUT MICROBIOTA INTERACTIONS RELEVANT FOR AESTHETICS MEDICINE Introduction Skin modifications in the course of time are the visible aspect of changes occurring deep within the body, at the systemic level, dealing with interactions between all organs and governing the global phenomenon of aging. Subtle changes in elasticity, smoothness and radiance of the skin surface are increasingly visible over years of exposure to external challenges and inner toxins, including delicate dysregulations. The link between inner and outer challenges has been identified and attention is paid to nutrition, detoxification and the pivotal role of the microbiota, in gut and on skin. The skin / gut microbiota continuum consists in bacterial communities « providing us with traits that we had not had to evolve on our own" (Thurnbaugh et al, 2007). They limit the proliferation of pathogens, produce microbial antibiotics, participate to food degradation and assimilation and limit the access of antigens to epithelial cells. The specific composition of the skin microbial communities supports local immunity and re-inforces the skin barrier function. Epidermal keratinocytes have the potential to affect cutaneous microbiota by producing antimicrobial peptides. Maintenance of the skin's microbiota is crucial in taming the consequences of the exposure to external challenges and inner toxins. In the gut, the microbiota selected by food intake contributes to the signaling between food components traveling in the lumen and the underlying mucosal immune system, protected by a thick mucus layer. Microbiota in the gut has also been identified in recent years to play a pivotal role of in regulating the "Leaky Gut syndrome" and its consequent rupture of tolerance exacerbated through stress-induced overexposure to glucocorticoids.

Preclinical and clinical studies on skin barrier and gut microbiota Several studies indicate that stress induces barrier disruption and leads to premature senescence. This seems particularly true in the skin, richly innervated and vascularized. Human and animal epidermal and dermal endothelial cells were studied for the expression of adhesion molecules, elicited either by pro-inflammatory cytokines or by mechanical stressors. In several gut models, from in vitro enterocytes cultures to rodents and human studies, the link between modifications of the intestinal microbiota upon anti-inflammatory treatment has been demonstrated. The barrier function is concomitantly modified, which testifies about the analogy between the protection provided by skin and gut microbiota. Results Preservation of the skin's resident flora is thought to be an effective way to maintain "normal" skin functions. Skin reacts to pro-inflammatory and / or mechanical stresses by enhancing repair processes associated to an intense neo vascularization. Our results show that its intensity can nonetheless be modulated. The visible result is a less intense repair activity and restoration of a more youthful skin. In the gut the alteration of microbiota strains (Clostridii vs coliforms) induced by anti-inflammatory treatment is associated to a concomitant barrier restoration, preventing generalization of the inflammatory process to the whole body.

Discussion In skin and gut, the protective barriers associated to a positive microflora function counteract the inflammation induced by stress, toxins and infections. Finely-tuned local microbiota interacts with and enhance the adaptive immune system. As in the gut, in the skin microflora, barrier function and immune system are closely interdependent and federated. A number of nutritional interventions are profoundly anti-inflammatory. Psychobiotics (a combination of pro- and prebiotics) have been shown to counteract the consequences of the stress-induced "leaky gut" through the production of short-chain fatty acids (SCFA). Oral administration of probiotic bacteria may represent a novel approach to protect the skin's immune system against UV radiation and that accelerated aging of the skin.

DECANGCHON Francis 101A (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS FACIAL FAT GRAFTING : HOW I DO IT Face fat transfers are a great way to restore a refreshed appearance in a quick and painless way, under local anesthesia with very minimal downtime. Facial creases such as laugh lines, smile lines and crow's feet result when underlying tissues that keep our skin looking youthful and plumped up begin to break down. To correct these defects, fat can be removed from the abdomen, thighs or other areas and transferred by injection to areas of the face.

Fat grafting involves harvesting fat from one part of the body, washing/purifying it, and carefully re-injecting it with specially designed needles/cannulas into areas requiring augmentation and enhancement. The procedure may need to be repeated several times to achieve the desired result. Unlike dermal fillers that are made from synthetic products, fat injections do not pose a possibility of an allergic reaction because the fat tissue is taken from your own body. Likewise, fat transfers can be used in larger volumes to fill larger defects. Above all, fat injections are a natural type of surgical enhancement, as well as containing small population of regenerating adipose stem cells.

As an added benefit, donor fat can be taken from trouble areas elsewhere on your body. Fat injected into areas requiring volume enhancement produces safe, long-lasting, and natural-appearing results as volume is replaced to tissues where fat is diminished. While fat injections do not stop the aging process, facial augmentation with human fat may help delay the need for more invasive procedures, such as a face lift, forehead/eyebrow lift or other types of surgery. Fat injections are also a beneficial addition to other cosmetic surgical procedures.

DECANGCHON Francis 201EF (LEVEL 2) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: ART & SCIENCE FOR THREAD-LIFTS (II): THREADS IN COMBINATION TREATMENT NON-SURGICAL THREAD RHINOPLASTY: TIPS & PEARLS A nose is considered "perfect' when it blends in well with your other facial features. Many Asians have ill-defined noses which lacks height and projection. Non-surgical nose thread lift treatment addresses this problem. PDO threads are inserted horizontally into the nose bridge and vertically into the nose tip. The threads act as a scaffolding structure which helps to contour and shape the nose to the desired state.

Non-surgical nose thread lift uses absorbable threads made of polydioxanone (PDO) that are 100% bio-compatible with the human body. Thanks to medical technology breakthrough in recent years, a "nose job" no longer means having to undergo a surgical procedure. A 30-minute non-surgical nose thread-lift is all you need to get a more defined, lifted nose. The embedded threads will completely dissolve after 6 to 8 months after the treatment. However, the nose will stay in its lifted position for another 8 to 12 months.

If the treatment is repeated about 9 to 12 months after the initial treatment, you can expect the result to be longer-lasting. With regular stimulation and production of collagen in the nose, some permanent lifting can be seen. Nose thread lift treatment are done by inserting a blunt cannula to achieve the desired height and projection. The risk of blindness from non-surgical thread lift is almost non-existent. DECANGCHON Francis 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: ULTIMATE FEMININE REJUVENATION DESIGNER BARBIE VAGINA: HOW TO ACHIEVE BETTER RESULTS More and more women are undergoing cosmetic genital surgery and the most popular of these procedures is labiaplasty, also known as "designer vaginal" surgery. This procedure involves the reduction of the vaginal lips, known as the labia, so the labia do not protrude. Women who have had greater exposure to images of vaginas in the media are more likely to consider labiaplasty. Women have become much more concerned about the appearance of their genitalia. In 2015, more than 95,000 women worldwide underwent the procedure, according to data from the International Society of Aesthetic Plastic Surgery (ISAPS). Labiaplasty as a cosmetic procedure focused on improving the appearance of the female genitalia will be discussed. Labiaplasty often focuses on the labia minora (inner labia), labia majora (outer labia), the clitoral hood, or a combination of areas. The sudden surge of popularity of Labiaplasty will be discussed as one of the fastest-growing plastic surgery procedures and reasons why it is popular. Approaches to achieve better outcomes and results will be presented. The preferred approach of the author will likewise be discussed, including advantages and disadvantages as well. Possible complications of the surgical procedure will be discussed as well. Labiaplasty is an increasingly popular procedure with high satisfactions rates, although the definition of labial hypertrophy and indications for surgery remain debated. Several techniques are available to accomplish labial reduction, and future studies are needed to establish practices optimizing patient care.

DECANGCHON Francis 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS FACIAL AND SUBMENTAL LIPOLYSS THERAPIES USING ALPHA 1-GLYCEROPHOSPHOCHOLINE (GPC) Through the years we have witnessed the appearance of several injection therapies which were introduced for the treatment of localized fat both in the abdomen, flanks, thighs, and most especially the face. Patients' interest in therapies to sculpt their bodies to make them more aesthetically acceptable, to enhance their self-esteem and increase their confidence level has dramatically increased in the recent past.

Mesotherapy, using a mixture of many pharmacological agents, has been in the forefront of all these lipolytic procedures to sculpt the face and body. One of the most commonly used drug, PPC (phosphatidylcholine), a phospholipid is used not only to stimulate the regeneration of hepatocytes, but has also an active role in destroying cell membranes of adipocytes, also causing inflammation and swelling that results in the contraction of the subcutaneous tissues which help break down fat and reduce the adipose tissues in vivo.

As a result of certain concerns regarding its side effects and complications, production of PPC had stopped since about 2 years ago, but a chemically similar pharmacological product, was introduced as an alternative lipolytic agent. This drug is alpha L-glycerophosphocholine (GPC), a natural phospholipid containing choline.

The combination of alpha L-glycerophosphocholine (GPC), lidocaine 2% and Normal Saline Solution when injected into the subcutaneous fat cause adipocyte breakdown hence abdominal and facial lipolysis are noted. The use of L-carnitine as the medication of mesotherapy for the reduction of the localized fat in unwanted areas in combination with Choline alfoscerate was added to the combination of these different pharmacological agents and it was shown to have synergistic effects. These pharmacological agents being used as lipolytic agents on the face and body parts have been positively observed to have a short downtime, the least adverse reactions, possibly hypoallergenic and most of all effectively dissolves facial fat, and the effect on the injected area is instantaneous or almost immediate results are observed when injected to the area to be treated even with just a small amount of the lipolytic agents

Therefore it is the conclusion of the author that alpha L-glycerophosphocholine (GPC) is an ideal lipolytic agent among the different injection therapies and mesotherapy medications available in the market now that would give us better fat dissolution results, is reproducible and without the notorious side effects and complications of other fat dissolving pharmacological agents.  

GRAZIANO Antonio 101A (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: REGENERATIVE MEDICINE, CELL THERAPIES & MICROBIOME FROM STEM CELLS TO TISSUE ENGINEERING: REALITY VERSUS THEORY Stem cells therapy aims to replace damaged or aged cells with healthy functioning cells in congenital defects, tissue injuries, autoimmune disorders, and neurogenic degenerative diseases. Among various types of stem cells, adult stem cells (i.e., tissue-specific stem cells) commit to becoming the functional cells from their tissue of origin. The stem cell therapy is mainly based on the use of Mesenchymal Stem Cells (MSCs) which are multipotent adult stem cells with unique biological properties. Several in vitro studies and preclinical animal models reported that MSCs are promising for cell therapy showing the ability to home to sites of inflammation after tissue injury, to differentiate into various cell types and secrete multiple bioactive molecules capable of stimulating recovery of injured cells by inhibiting inflammation by a paracrine effect. MSCs also show the lack of immunogenicity and have the ability to exert immunomodulatory functions. Today, many pathological conditions are treated with MSCs, such as ischemic cardiovascular diseases, critical limb ischemia, bone and cartilage regeneration or neural diseases. Tissue engineering is emerging as an interdisciplinary field in biomedical engineering that aims to repair diseased or damaged tissues or organs through the combined use of scaffolds and biologic mediators, such as for example stem cells and growth factors providing a new tool in the field of regenerative medicine. An example is represented by bioengineered skin substitutes which not only repair the wounds, but also have various supplements, such as growth factors, antibiotics and anti-inflammatory drugs which eventually fasten the wound healing process. In summary, here we present an overview of the current applications of both these approaches in the regenerative medicine.

GUEVARA Bryan 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: UPDATES IN DERMATOPATHOLOGY (LECTURES IN MANDARIN) TROPICAL AND MARINE DERMATOLOGY: WHAT LIES BENEATH? Asia has an abundance of natural coastal and marine scenery that is world-renowned for its beauty - from the pristine, white beaches of Palawan in the Philippines, to the sparkling shores of Hualien county in Taiwan. As the beauty of these seaside gems is attracting more attention from locals and tourists alike, dermatologists are encountering more cases of peculiar skin infections, unusual dermatoses, as well as atypical bites and stings from creatures inhabiting these waters. What are the evolutionary defence mechanisms displayed by these creatures, which result in these unfamiliar presentations? And how is climate change relevant? We will seek answers to these questions during our exploration of what lies beneath the skin (and seas) in terms of tropical and marine dermatoses. An understanding of these principles combined with guidance from dermatopathology will help clinicians unlock some of the mysteries of these fascinating cases of the deep, to better direct their management and make the unfamiliar familiar.

HSIAO Cheng-Hsiang 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: UPDATES IN DERMATOPATHOLOGY (LECTURES IN MANDARIN) HISTOLOGIC MIMICS OF BASAL CELL CARCINOMA Basal cell carcinoma (BCC) is the most common cutaneous malignancy. Histologically, BCC is characterized by the aggregations of monotonous basaloid cells with scant cytoplasm and focal peripheral palisading. The tumor nests are usually surrounded by fibromyxoid stroma with retraction of the tumor islands from the stroma. In most time, the diagnosis of BCC is usually straightforward. However, BCC can display a variety of growth patterns and overlap with many other skin tumors, including benign follicular neoplasms, such as trichoblastoma, trichoepithelioma and basaloid follicular hamartoma etc; sebaceous neoplasms including sebaceoma and sebaceous carcinoma. Occasionally, BCC may also present with adenoid structures and confused with eccrine or apocrine neoplasms such as adenoid cystic carcinoma and microcystic adnexal carcinoma etc. In the lecture, we will briefly review the histological variants of BCC and discuss the differential diagnosis between BCC variants and their mimics.

HSIAO Jack 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 15:00 Session: TELEDERMATOLOGY (LECTURES IN MANDARIN) THE NEW TELEMEDICINE LAWS AND ITS IMPACT TO TELEDERMATOLOGY PRACTICES IN TAIWAN The emergence of telemedicine and telehealth in recent decades and the increased adoption by private practices, hospitals, and healthcare groups has triggered an explosion in telemedicine-related legislation. In July 2018, Taiwan has passed the first telemedicine bill to regulate telemedicine and telecare schemes. HCC Healthcare Group and Taipei Medical University was among the first institutions to be accredited by both Minister of Health and Welfare and New Taipei City Department of Health, to conduct telemedicine practices under the new regulations, and teledermatology was the first initiate launched. We will discuss the new telemedicine laws and how it enforce a harmonization of standards for professional conduct deemed essential for healthcare delivery, and online prescribing regulations specifically ones that involved scheduled medications or those used for chronic disease or symptom managements, the government also mandates an in-person physical exam in order to legally prescribe medications to a patient over telemedicine. Impacts of the laws on teledermatology and patient-physician relationship, as well as patient's rights, telemedicine security and privacy issues, will be addressed.

HUANG Jeff Chen-Chieh 102 (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: STIMULATING INJECTABLES: WHAT'S NEW? COLLAGEN STIMULATORS: WHERE ARE WE AND HOW DO WE CHOOSE? How do you define a filler or a collagen stimulator? It's even more confusing now that hyaluronic acid (HA) has been reported to stimulate neo-collagenesis by mechanically stretching fibroblasts. What's the difference between a filler and a collagen stimulator? And how does it affect your choice when it comes to different indications or subgroups of patients? In this talk, we are going through the spectrum of foreign body reaction to different injectables (HA, PLLA, PCL, CaHA, PMMA, etc.). Histologic clues and macroscopic evidences will be presented. Understanding the mechanism will help us better select from our inventory when facing different clinical scenarios.

HUANG Jeff Chen-Chieh PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: SHOWCASE OF INJECTABLES: MIDFACE & NOSE - LIVE DEMO NOSE INJECTION IN ASIAN PATIENT Blunt nasal tip with upward rotation and recessed columella is usually considered a surgical indication. Filling the columella can forward the projection to some degree, but it can also turn up the nasal tip further, showing even more nostrils. Injection directly into the nasal tip can make some improvement; however, this is generally considered a dangerous area, particularly with needle injection. In this demo, we are going to tackle this difficulty with a special technique that Dr. Jeff Huang invented. This technique involves pre-treatment evaluation, proper selection of filling material and entry point, and proficiency in cannula use.

HUANG Jeff Chen-Chieh 101A (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 17:30 Session: FOCUS SESSION ON NOSE BEAUTIFICATION SHORT NOSE WITH UPWARD TIP PROJECTION: HOW DO I MANAGE IT? Asian noses are usually shorter and flatter. Filler rhinoplasty occupies a significant portion among our daily practice. Blunt nasal tip with upward rotation and recessed columella is probably the most difficult clinical scenario, and is usually considered as an indication for surgical rhinoplasty. In the talk, Dr. Jeff Huang is going to show a technique (J technique) that he invented to tackle this difficulty. This technique involves pre-treatment evaluation, proper selection of filling material and entry point, and proficiency in cannula use

HUANG Ching-Yu 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES NON-SURGICAL THERAPY FOR INGROWN NAIL AND PINCER NAIL Ingrown nail and pincer nail are commonly encountered diseases in dermatology clinic. In this session, I would like to share my experience of applying therapies other than surgery for correcting these conditions. HUANG Patrick Po-Han 101A (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: EXPERT'S ADVICES ON REJUVENATION DIFFERENT EMPLOYMENTS OF FOCUSED ULTRASOUND TO DIFFERENT AGING MORPHOTYPES IN ASIANS Employment of focused ultrasound greatly change and improve our non-surgical aesthetic treatment practices, especially in Asians. Our skin is thicker and delayed aging. We have thicker and more compact dermis which resists the formation of fine wrinkles and dynamic wrinkles. Asians have wider and rounder faces, but flatter midface. When we doing procedures to correct deficits, the facial structure differences will make the treatment different from what you use in Caucasians. For this talk, a new classification is proposed to show how I evaluate and treat patients in my practice.

Remember, we still have so many ways to solve aging problems. The layered anti-aging approach model to minimize risk, to reduce downtime and, most importantly, to maximize anti-aging effects was proposed in my lectures in IMCAS 3 years ago. Making very good use of these anti-aging methods, depending on the demands of patients and evaluations by dermatologists, we will offer the best of mono or combined therapy for our patients. Focused ultrasound is just only one of the important devices to tighten the deeper part of the skin.

HUANG Patrick Po-Han 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (LECTURES IN MANDARIN) WHY MINIMAL TOXIN DOSING? Botulinum toxin type A remains the most popular nonsurgical aesthetic treatment worldwide. Deciding the dosage of botulinumtoxin type A (BoNTA) to achieve cosmetic improvement is very important. However, a natural look dosage and long last effective dosing are different. In my practice, we adopted the patient-demand based satisfaction model (PBS): a lower initial dose followed by touch-up in 1 month.

Lower doses of botulinum toxin are appropriate for the many Asians who have a lower muscle mass and less hyperdynamic activity than Caucasians. The current trend for administering lower doses of botulinum toxin to most facial muscles, due to its marked responsiveness, is magnified in Asians. Minimal botulinum toxin dosing to meet PBS is not only to define the natural look dosage in Asians but also confirm the difference between the real-world use in East Asians and Caucasians-based guidelines and consensuses.

HUANG Yu-Chen 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES THE CLINICAL APPLICATION OF NAIL BRACE ACCORDING TO DIFFERENT TYPES AND CHARATERISTICS OF INGROWN NAILS Ingrown toenails cause pain, swelling, and paronychia, which interfere with patients' daily activities. Nail brace application is a new, effective, noninvasive approach for treating ingrown nails. Based on different characteristics, ingrown toenails could be divided into acute inflamed (AI) types and chronic dystrophic (CD) types. The treatment course and response are different according to the type and severity. Excellent results were more rapidly achieved in AI-type ingrown toenails; however, patients tended to be more easily irritated by the hook of the nail brace. In CD-type ingrown toenails, although it required longer treatment duration, nail brace application served as a good treatment option to relieve pain and achieve good cosmetic outcomes. The recurrence rate is around 7-10% after nail brace treatment. Maintenance nail brace therapy may be needed in patients who have higher risk of recurrence.

HUANG Yu-Ming 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ACNE AND ROSACEA FORUM TOPICAL IVERMECTIN: A NEW HOPE, A NEW CHALLENGE Rosacea is a chronic, relapsing disease with negative psychosocial impacts. Ivermectin 1% cream has shown its effectiveness in treating papulopustular rosacea in many different studies, and it is also effective for the clinical treatment of other types of rosacea with an overgrowth of Demodex mites. This emerging therapy has not only shown the importance of Demodex mites in the pathogenesis of rosacea, but has also changed and simplified the traditional therapies for difficult and challenging cases. Regular assessments of the number of Demodex mites before and after treatment can help doctors to decide the length of treatment course, monitor and predict the treatment response, and choose the proper combination of therapeutic modalities when single-agent treatment with topical ivermectin cream becomes less effective. For the patients without an increased number of Demodex, it seems that topical ivermectin cream can still relieve the symptoms of rosacea via additional mechanisms other than eradication of Demodex mites. This promising agent brings hope to patients suffering from the disease by relief of inflammation and improvement of skin texture, but may also result in some new problems, such as disruption of the balance of the skin microbiome. We must face some unexpected challenges which we have never encountered before.

HUANG Ching-Hsin 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: PHOTOMEDICINE CLINICAL EVIDENCES AND BENEFITS OF PICOSECOND LASER FOR MELASMA TREATMENT Clinically, melasma is a challenge benign pigmented disorder for treatment, especially in patients of dark skin type. Recently, several lasers have been proposed as treatment options for melasma. The novel picosecond laser, theoretically, is an ideal laser for selective photothermal melanolysis. In addition, the specific lens of picosecond laser may also provide an alternative treatment option. In this session, current clinical evidences and possible mechanisms in the treatment of melasma by picosecond laser will be reviewed. We would also like to share the treatment tips and experiences in Taiwan.

HUANG Hui-Peng 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (LECTURES IN MANDARIN) HOW TO PREDICT THE IMPORTANCE OF DEMODEX IN PATIENTS WITH ROSACEA? It has been studied that Demodex mites are higher in patients with rosacea than in the controls. Demodex might trigger inflammatory responses in rosacea through the chitin exoskeleton, resident bacteria or mechanical micro-abrasion with the mouth parts and claws. Furthermore, Demodex might cause large pores, fine white follicular plugs and orange skin-like appearance that are not the phenotype of rosacea. The importance of Demodex in patients with rosacea might be predicted based on a high density and the presence of features of demodicosis.

HUI Rosaline Chung-Yee 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: SNAPSHOTS OF RECENT ADVANCES IN SKIN THERAPEUTICS ADVANCES IN SKIN THERAPEUTICS: ACNE AND ROSACEA Acne and rosacea are common skin diseases, with multifactorial pathology. Several advances have taken place in the past decade in the research field, encompassing pathogenesis and development of new therapeutic interventions. The conventional approach for both diseases involves the use of topical therapy to treat inflammatory lesions in combination, when needed, with a systemic or topical antibiotic. An important issue in the management is the need to reduce antibiotic usage due to the increasing problem of bacterial resistance. Novel treatment options are now available for treatment of rosacea: topical alpha adrenergic agonist for rosacea-related erythema, topical ivermectin for inflammatory lesion

HUI Rosaline Chung-Yee 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: PEDIATRIC DERMATOLOGY CURRENT SYSTEMIC THERAPIES FOR PEDIATRIC ATOPIC DERMATITIS Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects children and adults. Until recently, the only approved systemic treatment option was systemic steroids, which are not recommended and are commonly associated with disease rebound. Many severe patients go untreated. In this session, currently available systemic options will be discussed, including off-label immunosuppressants and newly approved dupilumab, highlighting adverse effects and useful screens before prescription.

JUNG Wonsug PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: ANATOMY FOR AESTHETIC TREATMENTS: ANALYSIS WITH TIPS & PEARLS FOR INJECTABLES AND THREADS ANATOMY FOR AESTHETIC TREATMENTS: MIDFACE In this talk, the anatomy of midface, including nasolabial fold, Listow's space, and vascular anatomy of the nose, will be discussed.

JUNG Wonsug PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: ANATOMY FOR AESTHETIC TREATMENTS: ANALYSIS WITH TIPS & PEARLS FOR INJECTABLES AND THREADS ANATOMY FOR AESTHETIC TREATMENTS: UPPER FACE - PERIORBITAL REGION In this talk, the anatomy of periorbital region, including orbicularis ocluli muscle, orbicularis retaining ligament, orbital septum, deep fats, tear trough ligament, will be explained.

KAO Chao-Hsing 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 12:00 to 13:00 Session: VITILIGO (LECTURES IN MANDARIN) AUTOLOGOUS REGENERATIVE THERAPIES IN SEGMENTAL VITILIGO- RETROSPECT AND PROSPECT Segmental vitiligo (SV) is an acquired unilateral depigmentary disorder resulting from loss of functional melanocytes. The distribution may totally or partially match a cutaneous segment. Autologous regenerative therapies in SV include various phototherapies (UVA, PUVA, UVB, NB-UVB, He-Ne laser, red LED and other laser), surgical grafting, and platelet-rich plasma (PRP) intradermal injecton. In photobiomodulation therapy it promote ○1marginal repigmentation (perilesional melanocyte migration and proliferation), and ○2perifollicular repigmentation including:(a) differentiation of melanocyte stem cells in bulge of hair follicle, (b) immature melanoblast migration in outer root sheath of hair follicle, (c) differentiated melanoblast melanogenesis and migration. Patients with vitiligo are considered good candidates for surgical transplant depending on ○1limited extent( Contrary to generalized vitiligo, the survival of transplanted melanocytes is more predictable in SV. The autologous surgical transplanting include: (a)punch grafting(tissue graft),(b) epidermal blister grafting, (c) ultrathin epidermal sheet grafting, (d) cellular grafting (autologous epidermal cell suspension or pure cultured melanocytes). In surgical grafting, the survival, proliferation, and migration of living transplanted melanocytes are predictable. Autologous platelet-rich plasma (PRP) intradermal injection in combination with phototherapy or topical therapy is proposed to be a promising treatment.

KENCANAWATI Anne Carolina 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM ADIPOSE MESENCHYMAL STEM CELL FOR WOUND HEALING OF FACIAL SCAR Mesenchymal Stem Cell (MSC) has been found a new therapy for wound healing (facial scars), which is these cells are able to improve skin wound healing (facial scars) efficiencies by treating and preventing scar formation. We use Adipose tissue-derived MSCs which has biological advantages in the proliferative capacity, secreted proteins (basic fibroblast growth factor, interferon-y, and insulin-like growth factor -1), and immunomodulatory effects rather than bone marrow-derived MSCs. Adipose tissue-derived MSCs (AMSC) isolated from liposuction aspirates and must be stored in Cryo tank (liquid nitrogen) under the temperature of under -196 °C to stop the cell cycle process. AMSCs are widely available and abundant in cells, compared with the number of stem cells in 100 ml of bone marrow, 300 times as many AMSCs can be obtained from 100 g of fat tissue. We use AMSCs by injecting around the wound (facial scars area) and the result of all the process, it could reduce the scar formation.

KIM Hong-Seok 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? FUNCTIONAL RELATIONSHIP BETWEEN SKIN BARRIER AND COSMETICS If we drop a drop of water on our skin, it is not easily absorbed. The surface of the skin is covered with a fairly strong barrier so that even the water molecules can not easily pass through the skin, which prevents external substances from entering the skin easily while protecting the constituents of our bodies from the harsh environment. The stratum corneum is 10~20μm thick and embedded in intercellular space. The lipid located between the keratinocytes plays a role in preventing moisture loss by allowing the keratinocyte to be firmly bonded to each other. The skin barrier in the stratum corneum can be likened to brick (keratinocyte) and cement (intercellular lipid). The lipid located between the keratinocytes is called "intercellular lipid" because it is located between the cells. It is a lipid-soluble moisturizing factor mainly composed of ceramide, cholesterol and free fatty acid. As the epidermis differentiates, the protein in the cytoplasm, profilaggrin, is converted into filaggrin and finally decomposed into amino acids. As a result, the water-soluble moisturizing factor whose main component is the amino acid in the keratinocyte is called 'natural moisturizing factor (NMF)' I call it. The combination of the two makes it possible to maintain proper moisture on the skin and form a strong barrier from the outside, which is called the skin barrier.

Damaged or lack of natural moisturizing cells or intercellular membranes leads to increased water loss through the skin, resulting in dry skin as a whole. No matter how dry the surrounding environment is, there is the power to maintain moisture in the skin, but if the dry condition persists, the ability to retain moisture no longer disappears, eventually the skin barrier will collapse. This damaged skin barrier is prone to considerable irritation to small irritation, so it is essential to keep it healthy and healthy at all times. As the dam breaks up, it takes a long time to repair and restore it, but it is only a moment before the skin barrier breaks down. Just as skin that is built firmly does not collapse, so does skin. While it is important to avoid harmful ingredients, it is essential that you maintain good basic moisturizing care for your skin's tight skin barrier.

The skin usually has the power to pull moisture and the power to block it not to evaporate. The cosmetics we use are a combination of ingredients that pull moisture into the skin and prevents the moisture thus caught from evaporating. Cosmetics can play an important role in maintaining moisture in the skin because they have the same characteristics as the function of the skin. Knowing the intercellular lipid and natural moisturizing factors makes it easier to understand the ingredients and principles of moisturizers in cosmetics. I want to talk about the experiences of the lecturer on how to study and approach cosmetics through this lecture.

KIM Hong-Seok 101A (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: COSMECEUTICALS: WHAT'S NEW IN SKIN CARE ? HOW TO PRESCRIBE MOISTURIZERS ACCORDING TO SKIN TYPES Many people tend to use cosmetics that are used by celebrities, or suddenly when fashion-conscious products are released. So, despite the good skin condition, regardless of the type of skin indiscreetly using cosmetics, the skin condition is worse. Moreover, we have used cosmetics that others like, but have experienced problems . Just as we can not wear clothes when we buy clothes without considering the size and color because the clothes are just beautiful, cosmetics also have no effects if we do not consider our skin type. If we use the right cosmetics to suit our skin type, we can improve our skin without causing less problem, so the copy called 'I changed cosmetics only, my skin has changed everything' is not wrong. After all, it is important to use 'different' cosmetics for each other 'skin' type.

For example, 40/F

Her skin condition was not so bad as usual. She was always envious of her friends because she looked skinny and had tiny pores and looked young. However, a few days ago, her face began to get a little tingling, drier than before, she began to apply plenty of moisturizing creams. However, her face was getting red without improvement, and after when she woke up, her skin began to occur multiple acne lesions suddenly.

It may be due to the sudden drying of the surrounding environment or the habit of over-cleansing, it has damaged by intercellular lipid and NMFs, and skin barriers have damaged. Then, finally, the acne lesion began to rise as the skin barrier collapsed; it would be a chain reaction. Her skin type is dryness (D), sensitivity (S), non-pigmented (N), and tightness (T).

For dry and sensitive skin types (DS), there is a lack of water itself. It is also recommended to use humectants and occlusives together because the skin makes dehydrated due to lack of lipids that do not lose moisture from the skin.

KO William Wei-Chih 101A (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: EXPERT'S ADVICES ON REJUVENATION HOW TO OPTIMIZE COMBINED TREATMENT EFFECTS OF FACIAL SKIN TIGHTENING WITH INJECTABLES BY AGE SEGMENTATION Facial aging is a dynamic process involving the aging of soft-tissue and even bony structures. Epidermal thinning and the decrease in collagen and elastin cause skin to lose its elasticity. Fat atrophy, coupled with gravity and muscle over-contraction, leads to wrinkling and the formation of dynamic and static lines. These factors contribute to the formation of facial folds and the sagging appearance of aged facial skin. To reverse the aging signs, the rejuvenation strategies should be made according to the target sign. Combination therapy of injectables and non-invasive skin tightening devices offer satisfactory results and acceptable downtime. During the talk, I will share the tools and tips of this combination therapy by age segmentation.

KONTUREK Peter C. 101A (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: REGENERATIVE MEDICINE, CELL THERAPIES & MICROBIOME FECAL MICROBIOTA TRANSFER 2019: WHAT'S NEXT ? Fecal microbiota transplantation (FMT) is an administration of fecal solution from a healthy donor into the gut of a recipient to cure a specific dysbiosis-related disease. Multiple studies, including our own, demonstrated that FMT is a very effective in treating recurrent Clostridium difficile infection (CDI) with a reported success rates up to 90%. FMT is currently tested as a therapeutic option for a multiple diseases beyond Clostridium difficile. An important area of interest for FMT is the treatment of inflammatory bowel disease (IBD). Recently, the first randomized controlled trials exploring the use of FMT for treatment of IBD were published. The results are promising, but many questions remain unanswered in terms of donor selection, preparation of FMT and route of treatment (foregut, hindgut, or a combination). FMT appears to be a promising option to treat functional gastrointestinal disorders, especially irritable bowel syndrome (IBS). A recently published randomized trial demonstrated that 60% of patients treated with FMT via colonoscopy showed a significant clinical improvement. Interestingly, an another randomized study using encapsulated FMT applied by upper GI tract showed only the alteration of the gut microbiota but no significant clinical improvement. Further studies are required to clarify the role of FMT in the treatment of IBS. New emerging indications for FMT include eradication of the intestinal colonization by multidrug-resistant pathogens, autologous FMT for reconstitution of post-antibiotic gut microbiome, therapy of hepatic encephalopathy and nonalcoholic steatohepatitis (NASH) In summary, the restoration of gut microbiota by FMT holds promise that this method may be effective in the treatment of infectious, inflammatory and functional disorders of gastrointestinal tract.

KUO Hsiao-Ling 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 08:30 to 09:30 Session: INTERFACE BETWEEN RHEUMATOLOGY AND DERMATOLOGY (LECTURES IN MANDARIN) DERMA LUPUS OVERLAPS Timely and accurate recognition of collagen vascular diseases as lupus or dermatomyositis ,and implementation of effective screening and referral processes forpatients suspected of having such disease, remain a challenge for many physicians. The result, too often, is unnecessary testing and referrals, and in some cases unnecessary anxiety for physicians, patients, and parents. Physicians have to learn to recognize the common clinical symptoms and signs of systemic lupus erythematosus, dermatomyositis, and their distinction from common infectious mimics. We also have to learn to recognize the testing that can clarify the likelihood of whether a patient has a rheumatic disease, including the limited utility of early serologic testing for autoantibodies. LAI David Ying Ching 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING PREVENTIVE ONCOLOGY IN ANTIAGING MEDICINE PRACTICE Benign & malignant growth are common in antiaging medicine practice. While no clear cut evidence of HRT in cancer induction, the possibility of hormone therapy being contributory in neoplastic progression can not be rules out. Recent studies showed that multinodular thyroid that frequently seen in clinic, are in fact occult malignancy in 8 to 23 % of cases in post thyroidectomy specimens. The management of this risk in antiaging patient with thyroid nodules will be discussed.

LAI Feng-Jie 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: PHOTOMEDICINE PHOTOCHEMISTRY IN THE SERVICE OF DERMATOLOGY Photodynamic therapy (PDT) is a modern, non-invasive therapeutic method used for the destruction of various cells and tissues. The combined use of a photosensitizing agent, light of specific wavelength and dioxygen for the treatment of diseases was first discovered more than one hundred years ago, but application as a routine method is still limited. The development of modern PDT since the beginning of the twentieth century is briefly portrayed. The underlying mechanisms of phototoxicity are explained, and the requirements for ideal photosensitizers (PS) are underlined. Selected PS are introduced and examples of some of the many attempts made at the optimization of PDT by developing new PS with improved chemical and phototoxic properties, with emphasis on cutaneous lesions are reviewed.

LAI Po-Ju 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: WHEN AND HOW TO USE BIOLOGIC AND SMALL MOLECULE THERAPIES (LECTURES IN MANDARIN) EMERGING THERAPY-SMALL MOLECULE DRUG IN DERMATOLOGY Dermatology is entering an exciting area with new, targeted immune-modulating medication for treating a variety of dermatologic disease including psoriasis, atopic dermatitis, alopecia areata and other chronic inflammatory skin disease. In recent decade, because of more clearly understanding of disease pathogenesis and cytokine signaling cascades, biologics which we are familiar with are used to treating multiple dermatologic diseases. Besides, there is another new class, small molecule drugs , which has drawn our attention in these 5 years. Small molecule drugs (inf 1 kDa) have bioavailability with oral administration and easily cross the epidermal barrier through topical application. Their target is intracellular. Within the intracellular space, they can inhibit their target signaling pathway by modulating nuclear transcription. From this lecture, the audience can learn the mechanism and development of small molecule drug and get the latest information about this new generation of drugs.

LEE Geun Soo 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES GRADATIONALLY APPROCHED STRATEGY FOR VARIOUS ENLARGED OR CLOGGED PORE TREATMENT BASED ON EBD Visible enlarged pores or sebum clogged pores are regarded as an annoying issue, especially for young people. It is very common feature on seborrheic area of the face. A lot of lasers, radiofrequency, mocrodermabrasion and other enrgy based devices has been used for pore size reduction and pore cleaning. Genetic predisposition, sex, aging, chronic ultraviolet exposure, cosmetics, and amount of sebum excretion are known related factors for enlarged pores. The treatment strategy for enlarged or clogged pores should be selected depends on cause and skin condition of each patients. So, it has to be correct decreased elasticity of peri-pore tussue, increased sebum production inside of pore, and sebum clogging on the surface of pore. Topical retinoic acids or chemical peelings can be applied as supplimentary treatment for enlarged pores, but for skin rejuvenating effect of EBD is important to improve the elasticity of pore surroundings. LEE Geun Soo 101A (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:30 Session: TOP CLINICAL CASES: INTERACTIVE DISCUSSION PIGMENTARY DISORDERS All the involved procedures of pre-treatment care, treatment parallel care, and post-treatment care are important to get optimal results. Recently many doctors insist early intervention of scar treatment is necessary to reduce scars. The treatment response against pigmented lesions is very diverse according to distribution pattern, lesion depth, or color.

LEE Mei-Ching 201EF (LEVEL 2) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: EMERGING ENERGY- BASED DEVICES: PICOSECOND LASERS - WHERE ARE WE NOW THE ROLE OF PICOSECOND LASER IN MELASMA TREATMENT Melasma has a high prevalence rate in Asia women, primarily in child-bearing women. There are many treatments of melasma, includes topical agents, oral pills, chemical agents, laser and light therapies, etc, but it is a recalcitrant pigmentation disorder that there is no single cure modality now. In recent years, the picosecond laser becomes more and more popular for melasma treatment in Asia. But only very few studies were reported until now. Is the picosecond laser really safer and more effective than other modalities in melasma treatment?

LEYLEK Ozgur 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: ULTIMATE FEMININE REJUVENATION FUNCTIONAL VALUE OF PERINEAL BODY IN FEMALE SEXUALITY - INTROITAL TONGUE For years, many scientists studied to explain how female sexuality works. Nowadays, we certainly know that the female sexuality depends on multiple factors both phsycologic and physiologic. And we understood that the perineal body becomes more important for sexual satisfaction in both males and females then before in time. Many studies showed that pressure on the perineal body increases the sexual pleasure and satisfaction. In this individual study, we chose the women from the patients who applied to our clinic with complaints of sexual pleasure and satisfaction deficiency. We injected a combined cross-linked Hyaluronic Acid into the mucosa of the posterior wall of vagina in a special shape that we call it INTROITAL TONGUEá´¿ . With this application, we aimed both magnifying the pressure on the perineal body during the sexual intercourse and tightening the introitus mechanically. We evaluated the subjects before and 3 weeks after applications with FSFI (Female Sexual Function Index) and a basic 5 Points Likert Scale. Most of the women declerated an increasing sexual pleasure and satisfaction with a shortening of time to get orgasmic end. We determined an acceptable improvement at FSFI and the 5 Points Likert Scale after the application. And we surprisingly noticed that the male partners of these women notified that they have an increased pleasure during the sexual intercourse especially in classical missionary position. In conclussion; although various kind of filler application techniques have been done to increase sexual pleasure and satisfaction till today, it is seen in our study that effectiveness of the INTROITAL TONGUEá´¿ is uncontrovertible. And although we need further studies with larger series, we hope that the INTROITAL TONGUEá´¿ will be a new alternative technique of injecting fillers intravaginally to increase the female sexual pleasure and satisfaction.

LEYLEK Ozgur 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: ULTIMATE FEMININE REJUVENATION INTRAVAGINAL THREAD PROCEDURES FOR REJUVENATION, TIGHTENING (VTT-L/ VTT-C) AND STRESS URINARY INCONTINENCE (PUTL) There are many kind of threads are used in aesthetic medicine. Development in their production technology made their fields of usage more wider than before. Recently, threads entered the cosmetic gynecology as a new field. In our study, we aimed to show the efficiency of COG (barbed) for rejuvenation, tightening and lifting of vaginal mucosa. We chose the subjects from the patients who applied to our clinic for sexual pleasure deficiency related to vaginal relaxation and we excluded the others who had POP (Pelvic Organ Prolapsus) or/and other systemic contraindications. Under the local anesthesia, we inserted the threads into the vaginal mucosa by our two new techniques, VTT-Lá´¿ (Vaginal Thread Tightening-Longitudinal) and VTT-Cá´¿ (Vaginal Thread Tightening-Circular). All patients were evaluated by FSFI scoring (Female Sexual Function Index) and by 5 Points Likert Scale for the patient satisfaction before and after the procedure. We also used COG threads by our other technique, PuTLá´¿ (PeriUrethral Thread Lifting) for SUI and evaluated the results with a micturition diary. We determined that vaginal COG applications tighten the vagina by mucosal thickening with biological and mechanical effects. As a result, we found an acceptable difference between before and after scoring of the validated questionaries and most of the patients declerated the results good / very good. Although there isn't any published study about intravaginal COG thread applications in literature yet and we could not have enough number of patients, most of the women included in our study declerated that they were satisfied from the results. We believe that intravaginal thread applications can be an alternative to other non-surgical or surgical vaginal tightening and therapeutic SUI methods in future.

LI Chien-Nien 102 (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: PITFALLS TO AVOID IN AESTHETIC PROCEDURES MANAGEMENT OF DERMAL FILLER COMPLICATIONS: COMMON AND SEVERE ADVERSE EVENTS In this session, the speaker would go through some common and serious adverse effects of dermal filler injection. Focusing on the latest consensus of about how to use hyaluronidase (in HA related intravascular events) and the possible solutions of non-degradable fillers.

LI Jack Yu-Chuan 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 15:00 Session: TELEDERMATOLOGY (LECTURES IN MANDARIN) TELEDERMATOLOGY IN TAIWAN, WHERE TO BEGIN? With newly passing law of telemedicine in Taiwan, it sudden seems possible that a dermatology consultation session can be more than just face-to-face. A well-planned teledermatology process is now feasible within the limit of the law and may even be reimbursable in the future. But besides the hassle of the law and reimbursement, what are the possible technologies and models that can make a routine teledermatology possible in Taiwan? The speakers will provide their experience in implementing a teledermatology setting for chronic care patients and a step-by-step process of where to begin this endeavor.

LIANG Ben Chung-Pin 201EF (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ART & SCIENCE FOR THREAD-LIFT (I) SUBZYGOMATIC THREAD LIFTING- DIRECT METHOD TO TREAT SAGGING BUCCAL FAT PAD Thread lifting in the aesthetic field has become more and more popular in recent years. Quill®, V-lock®, Silhouette instalift®, Stratafix® PDS plus and Miracle® thread are available in absorbable suture products for thread lifting in Taiwan. Suture lifting has not only let physicians give an immediate, directional, line contouring effect of the face, but also, the suture can stimulate an inflammatory response that leads to collagen regeneration. In the development of the suture lifting technique, subcutaneous layer of the skin is recommended for thread administration, owing to the rejuvenation effect and safety consideration. However, "subcutaneous" thread lifting may lead to widening ofthe face when dealing with the lower face, and difficulty in correcting "perioral fat" due to descending deep buccal fat pad. The technique of sub-zygomatic thread lifting could resolve the issue above and is relatively safe.

LIAO Yi-Hua 201EF (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA MELASMA: AN UP-TO-DATE COMPREHENSIVE REVIEW AND THE APPLICATION OF IN VIVO IMAGING Melasma is a common acquired chronic disorder of symmetrical hyperpigmentation, occurring most commonly on the face. Melasma predominantly affects women with Fitzpatrick skin phototypes III and IV and often lasts for decades after pregnancy, leading to considerable embarrassment and emotional distress. The major etiological factors of melasma include genetic factors, UV or visible light exposure, hormone and vascular factors. The treatment of melasma remains a challenge. Numerous treatment options, including topical agents, chemical peels, oral medications and energy-based treatments have been exploited without predictive and satisfactory outcomes. The measurement of epidermal melanin content, the number and activation status of melanocytes, and dermal melanophages can provide important histopathologic information to evaluate the severity of melasma. In vivo harmonic generation microscopy (HGM) can provide a non-invasive method of skin optical biopsy. We examined melasma lesions before and after treatment of triple combination cream and low-fluence 1064-nm Q-switched Nd:YAG laser by in vivo HGM. The results showed decreased amount of epidermal melanin, but increased number of dermal melanophages and increased melanocytic dendriticity after treatment, which may imply the possibility of future relapse of melasma.

LIAO Yi-Hua 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) TARGETED THERAPY FOR MALIGNANT MELANOMA About 70% of patients with cutaneous melanoma harbor mutations on key signaling oncogenes. These oncogenic mutations, which are associated with melanoma cell proliferation, cell cycle progression, and malignant phenotype, can be used as targets for melanoma therapy. Among them, the mitogen-activated protein (MAP) kinase signaling pathway is the most important signaling pathway related to melanomagenesis and its progression. Approximately 50-60% of superficial spreading melanomas and 16% of acral lentiginous melanomas harbor a mutation in the BRAF gene that leads to constitutive activation of downstream signaling through the MAP kinase pathway. Despite the excellent progression-free survival (PFS) and overall survival (OS) from BRAF kinase inhibitors in patients with metastatic melanoma harboring a BRAF V600 mutation, the average duration of the response was short due to the rapid development of multiple mechanisms of resistance. The combination therapy with MEK inhibitors is an excellent strategy to circumvent drug resistance. The combination of BRAF/MEK inhibitors with chemotherapy, radiotherapy, immunotherapies, or other targeted therapies may offer long-term control of melanoma in the future.

LIM Ting Song 101A (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: EXPERT'S ADVICES ON REJUVENATION PARADIGM SHIFT IN DERMAL FILLERS USE: MOVING AWAY FROM VOLUME BASED INJECTIONS (VBI) Hyaluronic acid (HA) fillers have gained popularity as the basic entry to facial rejuvenation. The current trend in HA filler delivery is mostly relied on multiple point injections, using large volume, aiming for both immediate volume increment and lifting. However, such practice often ignore the short term as well as long term consequences, such as implant diffusion, migration, inflammatory reaction as well as facial contour distortion leading to facial overfilled syndrome (FOS). Hence, a more improved, efficient method using minute amount of HA fillers via minimal entry points is warranted.

We look into the dangers of current practices with fillers, which solely relied on the volume effect. We termed it "Volume Based Injection" (VBI), where the results depends on the volume of the products injected. We recommend that such approach should be revised to a more considerate and efficient way to deliver dermal fillers. Approaches that use very small amount of fillers with different rheological properties at strategic areas, in several different layers of the soft tissues is most favourable. Such technique should achieve satisfactory volume correction devoid of complications.

LIM Ting Song 101A (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:30 Session: TOP CLINICAL CASES: INTERACTIVE DISCUSSION INJECTABLES Interesting cases to be revealed.

LIM Ting Song 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS ICE-FIRE FOR BETTER BODY CONTOURING In recent year, body aesthetic has gained popularity in the industry. Many non-invasive fat reduction devices have surfaced in the market, boosting the adoption of non-surgical fat reduction procedures over others. Cryolipolysis using technology developed from Harvard University made a groundbreaking change in how we perceived body contouring. It is later joined by Thermolipolysis technologies based on radiofrequency (RF) and lasers. However, each technology has its strength as well as weaknesses. But combining the strength of each technology, overcoming their weaknesses, could lead to more consistent efficacious treatment for body contouring and minimizing possible complications.

LIN Liang-Chen 102 (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: STIMULATING INJECTABLES: WHAT'S NEW? SIMPLIFIED STEP-BY-STEP INJECTABLE PLLA TREATMENT (4S TREATMENT) STRATEGY WITH CANNULAS FOR ANTI-AGING The establishment of accurate assessment for patient need and treatment plan for injectable PLLA is sometimes difficult due to following reason:1. Treatment needs 1-3 months to achieve desire result (hard to predict by treatment area and amount.) 2. The Characteristics of injectable PLLA is watery, the injection technique can't easily standardize. Here I will share the Simplified Step-by-Step Treatment of injectable PLLA with cannula to help establishing predictable result and optimizing treatment plan for the patient's need.

LIN Chia-Chi 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) IMMUNOTHERAPY IN MALIGNANT MELANOMA Over the past 10 years, increased biological understanding and access to innovative therapeutic substances have transformed advanced cutaneous melanoma into a prototype for testing checkpoint-modulating agents, which has increased hope for long-term tumor containment and a potential cure. These expectations have been substantiated by clinical success with antibodies that block PD-1 and CTLA-4.

LIN Yi-Ting 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: URTICARIA AND PRURITUS (LECTURES IN MANDARIN) INFINITE ITCH IN CHRONIC URTICARIA: PROGRESS TOWARD PATHOGENESIS AND TREATMENT Infinite itch in chronic urticaria: Progress toward pathogenesis and treatment Chronic spontaneous urticaria (CSU) is defined as the appearance of evanescent wheals, angioedema, or both, for at least 6 weeks. CSU is associated with intense pruritus and poor quality of life. Patients have higher odds of reporting mental health problems, such as depression, anxiety, and sleep difficulty. Clinicians commonly face the difficulty assessing the "true" disease severity in these patients. The assessment of the activity and course of the disease along with the response to several treatments in CSU are based purely on the patient's medical history and the use of the patient-reported outcomes. Some patients may still suffer from severe pruritus even when wheals become rare on themselves. Recently, several reports have suggested that certain parameters could be considered as potential disease-related biomarkers. Moreover, with the advent of such biomarkers, newer biologic agents are coming forth to revolutionize the management of this potential refractory disease and the protracted itch. Understanding the mechanisms of action and therapeutic effectiveness of the latest agents for the management of antihistamine-refractory CSU could have an important impact on the management and follow-up of patients with CSU.

LIN Yi-Ting 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS MANAGING ATOPIC DERMATITIS: DIFFERENCES BETWEEN ADULTS AND CHILDREN Atopic dermatitis (AD) can present very differently in adults than in children. The differential diagnosis of atopic dermatitis is much broader in adults than the pediatric cases. Patients may also report adult-onset skin disease. Diagnosis can be difficult or controversial in some cases in spite of available diagnostic criteria listing in the guidelines. Adults with AD are usually severe and greatly affected by the disease. We should pay attention to the non-dermatologic comorbidities, especially the mental health problems in these adult atopic dermatitis patients, such as anxiety and depression. Symptoms of anxiety and depression may improved with adequate treatment of atopic dermatitis signs and symptoms, and vice versa. Recent development of new target therapies has been a game-changer in the management of moderate-to-severe atopic dermatitis.

LIN Jeng-Hsien 201EF (LEVEL 2) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: EMERGING ENERGY- BASED DEVICES: PICOSECOND LASERS - WHERE ARE WE NOW IS FRACTIONAL FOCUSED PICOSECOND LASER NECESSARY FOR MELASMA TREATMENT ? A HISTOLOGICAL STUDY Melasma is a difficult pigmentary disease for its frequent recurrence and resistance to treatment. Multiple possible etiologies were involved in the pathogenesis. Besides topical and oral medications, laser toning with Q-switched lasers become one of the powerful weapons to fight melasmain for more than 10 years. However, complications such as mottled dyspigmentation can take place because the nanosecond lasers may be lethal to melanocytes.

The picosecond laser is a novel treatment modality for pigment removal. The short pulse duration in the picosecond domain is able to exert more photomechanical than photothermal effect, resulting in stronger power to fracture the melanin with less chance of side effects such as post-inflammatory hyperpigmentation.

The picosecond lasers have been used to treat melasma in some studies. However, there is still no universal protocol to treat melasma perfectly. By the way, there has been no detailed histological study of the picosecond laser to optimize the parameters for melasma.

We did an in vivo histological study of the fractional 532nm and 1064nm handpieces with serial fluences. In 532nm wavelength, there is a threshold above which laser-induced optical breakdown (LIOB) can take place. This finding suggests that in melasma, fluence below the LIOB threshold may be safer for melasma treatment in that melanin from the ruptured keratinocytes by LIOB may drop into the dermis through the defective basement membrane, which is one of the pathomechanism of melasma.

LU Sophie Pei-Hsuan 101A (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: DERMATOLOGIC & COSMETIC SURGERY: COMPREHENSIVE AND CONCISE METHODS FOR IMPROVING YOUR RESULTS PAN-FACIAL REJUVENATION WITH LIPOSCULPTURE, FAT GRAFTING AND THREAD LIFT Facial sculpting is achieved by a combination of procedures, ranging from non-invasive, minimally-invasive to invasive procedures. For soft tissue sculpting, increase and decrease in volume must be balanced in different area of face. In the talk, I will discuss about soft tissue augmentation, facial liposuction, and thread lift. Nanofat grafting and stromal vascular fraction injection will be covered to enhance facial rejuvenation. In addition, a novel idea of "Composite Layering Thread Lift" will be introduced to increase the performance of thread lift.

LU Chun-Wei 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: DRUG REACTION (DRUG ALLERGY & CANCER TREATMENT-RELATED SKIN REACTION) MANAGEMENT OF EGFR INHIBITORS INDUCED NAIL DISORDERS Inhibition of the epidermal growth factor receptor (EGFR) pathway has recently been used as a form of treatment for advanced solid organ malignancies such as non-small-cell lung, head and neck, pancreatic, and colon cancers. Treatment of non-small-cell lung cancer by targeting the EGFR pathway has become a standard practice for patients with an EGFR mutation. Nonetheless, adverse events such as acneiform rash, , photosensitivity, and paronychia commonly occur after the use of EGFR inhibitors.1 Due to the fact that such adverse dermatological events may affect patients' quality of life (QoL) and compliance with EGFR inhibitors, many strategies have been suggested by experts to manage these events. Paronychia is an inflammatory process involving the soft tissues around the nails of the fingers and toes. It most commonly occurs on first digits and has been reported to be found in about 15% to 20% of patients treated with EGFR inhibitors. Unlike common chronic paronychia, most of the paronychia in patients receiving EGFR inhibitor therapy involves large -like lesions. The granulation tissues cause the periungual area to become very painful and to bleed easily. At present, there is no efficient, non-invasive, and pain-relieving treatment for high grade paronychia with pyogenic granuloma-like lesions. The condition can only be treated with potent topical steroids, topical or systemic antibiotics, aqueous silver nitrate, topical trichloroacetic acid, antiseptic soaks, and sometimes, even partial nail plate avulsion is required depending on the severity of the symptoms. However, a treatment such as nail plate avulsion causes severe tenderness and decreases a patient's QoL. A temporary dose reduction in EGFR inhibitors is also recommended for severe paronychia to alleviate this adverse effect, but a dose reduction can also reduce the efficacy of the cancer treatment. In this talk, I will provide you a better way to reduce the pain and avoid paronychia induced EGFR inhibitors dose reduction or drug shifting.

LU Chun-Wei 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: DRUG REACTION (DRUG ALLERGY & CANCER TREATMENT-RELATED SKIN REACTION) MANAGEMENT OF EGFR INHIBITORS INDUCED NAIL DISORDERS Inhibition of the epidermal growth factor receptor (EGFR) pathway has recently been used as a form of treatment for advanced solid organ malignancies such as non-small-cell lung, head and neck, pancreatic, and colon cancers. Treatment of non-small-cell lung cancer by targeting the EGFR pathway has become a standard practice for patients with an EGFR mutation. Nonetheless, adverse events such as acneiform rash, stomatitis, photosensitivity, and paronychia commonly occur after the use of EGFR inhibitors.1 Due to the fact that such adverse dermatological events may affect patients' quality of life (QoL) and compliance with EGFR inhibitors, many strategies have been suggested by experts to manage these events. Paronychia is an inflammatory process involving the soft tissues around the nails of the fingers and toes. It most commonly occurs on first digits and has been reported to be found in about 15% to 20% of patients treated with EGFR inhibitors. Unlike common chronic paronychia, most of the paronychia in patients receiving EGFR inhibitor therapy involves large pyogenic granuloma-like lesions. The granulation tissues cause the periungual area to become very painful and to bleed easily. At present, there is no efficient, non-invasive, and pain-relieving treatment for high grade paronychia with pyogenic granuloma-like lesions. The condition can only be treated with potent topical steroids, topical or systemic antibiotics, aqueous silver nitrate, topical trichloroacetic acid, antiseptic soaks, and sometimes, even partial nail plate avulsion is required depending on the severity of the symptoms. However, a treatment such as nail plate avulsion causes severe tenderness and decreases a patient's QoL. A temporary dose reduction in EGFR inhibitors is also recommended for severe paronychia to alleviate this adverse effect, but a dose reduction can also reduce the efficacy of the cancer treatment. In this talk, I will provide you a better way to reduce the pain and avoid paronychia induced EGFR inhibitors dose reduction or drug shifting.

LU Po-Hsuan 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ACNE AND ROSACEA FORUM THE CLINICAL EVALUATION AND THE TREATMENT OF POST-ADOLSCENT ACNE IN WOMEN Women with post-adolescent acne have acne primarily involving face and undergone standard acne treatments without success. A survey of adult postmenopausal women who failed standard acne treatments shows features suggesting hyperandrogenism, such as acne distribution on the lower face area. We tend to of describe the correlation facial distribution of acne by the objective method, acne lesions counts to assist diagnosis. In women with post-adolescent acne, the severity of acne has not been well quantified, and an acne lesion count is objective measure of acne severity. By quantifying severity of acne, we would like to examine the clinical feature of women with post-adolescent acne to establish etiologic factor which will merit further investigation. This group of women with treatment-resistant, late-onset, or persistent acne may seek complementary and alternative medicine.

MANUSKIATTI Woraphong 201EF (LEVEL 2) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: EMERGING ENERGY- BASED DEVICES: PICOSECOND LASERS - WHERE ARE WE NOW PICO TONING: A GAME CHANGER IN FACIAL REJUVENATION "Laser toning'' using low fluence, large spot size, multiple passed Q-switched 1,064nm Nd:YAG laser has gained much popularity in Asian countries for non-ablative skin rejuvenation, skin brightening, and the treatment of melasma. An attractive aspect of non-ablative skin rejuvenation is the relatively lower risk of complications and downtime compared with ablative skin resurfacing. It has therefore gained much popularity among Asians with mild to moderate degree of photoaging. Laser toning involves the use of a large spot size, low fluence, multiple-passed QS 1,064nm Nd:YAG laser (e.g., 6-8mm spot size, 1.6-3.5 J/cm2) to achieve the clinical endpoint of mild erythema. The procedure is often performed every 1-2 weeks for a course of several weeks to even months. Although laser toning is commonly performed, its efficacy for skin rejuvenation and melasma has only been documented in a few clinical studies. In addition, the development of hypopigmentation and depigmentation after a series of laser toning with low fluence QS 1,064nm Nd:YAG laser is a common adverse effect that is a major drawback of this treatment technique. Picosecond laser represent a novel technology in the treatment of unwanted pigmented lesions. Laser toning using picosecond laser has been applied for skin rejuvenation, dyspigmentation and scars. Its efficacy and side effect will be shared and discussed.

MANUSKIATTI Woraphong 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES NECK REJUVENATION USING A FRACTIONAL RADIOFREQUENCY DEVICE Demand for noninvasive procedure to correct the of the unattractive feature of an aging neck is increasing because of the popularity of aesthetic medicine. However, data on the safety and efficacy of noninvasive procedures for treatment of aging neck skin in the dark-skinned patients are limited. Safety and efficacy of a fractional radiofrequency microneedle system for the treatment of aging neck skin in Asians will be shared and discussed.

MANUSKIATTI Woraphong 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM FRACTIONAL PICOSECOND LASER FOR TREATMENT OF ATROPHIC ACNE SCAR Background: Fractional 1,064-nm picosecond-domain laser has recently been applied for treatment of atrophic scars and given encouraging results. However, data on the safety and efficacy of this procedure in the dark-skinned patients are limited. Objective: This prospective, self-controlled study was conducted to evaluate the safety and efficacy of a 1,064-nm picosecond laser coupled with micro lens array (MLA) for the treatment of atrophic acne scars in Asians. Study Design/Materials and Methods: Twenty-six subjects of skin type IV and V with atrophic acne scars were enrolled. All subjects were treated on the six-monthly sessions with a 1,064-nm picosecond laser (spot size of 8 mm, fluence of 1.0 J/cm2, repetition rate of 10 Hz) in combination with the MLA device for an average of 3 passes. Objective (measurement of scar volume using 3D photography and skin roughness analysis using ultraviolet A-light video camera) and subjective (clinical evaluation by two blinded dermatologists) assessments were obtained at baseline and at 1, 3, and 6 months after the final treatment. Results: At the 6-month follow-up, 53.8% of the subjects were rated as having at least 50% improvement of the scars. The rate of improvement has significantly increased from the 1-month follow-up to the 6-month follow-up (P = 0.013). At the 6-month follow-up, the scar volume (P = 0.024) and the skin roughness (P = .001) have significantly improved, in comparison with the baseline. Mild postinflammatory hyperpigmentation (PIH) was observed in 15% of the subjects. All PIH was temporary and resolved on an average of 4 weeks. Conclusions: The 1,064-nm picosecond laser with MLA is a safe therapeutic alternative for the treatment of atrophic acne scars in dark-skinned individuals.

MARINI Leonardo 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES LED PHOTO-BIOMODULATION AND CARBOXYTHERAPY IN NON SCARRING ALOPECIA Variable forms of hair-loss affect the majority of the population worldwide inducing patients to seek medical attention with the aim of identifying possible effective treatments. IR(840-nm) and Red (633-nm) LED photo-biomodulation is rapidly gaining popularity among patients. This treatment is able to temporarily improve all three forms of alopecia: AGA - Androgenic Alopecia; AA - Alopecia areata; CIA - Chemoteraphy-induced alopecia through mobilization of stem cells out of their hypoxic niches + inducing their differentiation and proliferation. Low dose photo-biomodulation therapy is based on non-ionizing, non-thermal bio-photonic irradiation of exposed tissues. It has proven effective in alleviating pain and inflammation and promoting wound-healing and/or tissue regeneration. This form of treatment was discovered by accident during an experimental study performed at Semmelweis University (Hungaryby Prof. Endre Mester ) in 1967. He was trying to reproduce a successful oncologic treatment with a 695-nm laser in rats as performed by Prof. Paul McGuff in Boston (US). Unfortunately his laser source was not as powerful as the one used in the US and the experiment failed but non completely, because he observed thicker and denser hairs and rapid wound healing on irradiated rats. Selected Red and IR wavelengths can be absorbed by cytochrome C oxidase and porphirins contained in mitochondria increasing ATP, inducing production of ROS, and stimulate cell signalling and gene transcription. Currently LED photo-biomodulation is currently used in anti-aging, wound healing, tissue regeneration, acne treatment, melasma treatment, PIH treatment, rosacea treatment, and hair growth treatment protocols. A large body of literature confirmed the effectiveness of LED photo-biomodulation in non-scarring forms of alopecia. Carbon-dioxide therapy commonly known as carboxytherapy refers to the administration of CO2 with therapeutic purposes. Its first use was reported in 1932 in France when it was successfully used percutaneously to treat peripheral arteriopathy and venous ulcers. Modern techniques involve intradermal or subdermal injections of small volumes of heated CO2 with the purpose of activating tissue oxygenation through a direct/indirect action on the microcirculation. A recent publication on a sample of 40 AA and 40 AGA patients confirmed the efficacy of this treatment in temporary improving hair density in treated areas. The sequential combination of LED photo-biomodilation and carboxytherapy can achieve positive synergistic effects on treated tissue further improving early and late clinical results.

MARINI Leonardo 101A (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: EXPERT'S ADVICES ON REJUVENATION IR LASER PHOTOTHERMAL TISSUE PRE-CONDITIONING BEFORE HA FILLERS HELPS TO OPTIMIZE AND PROLONG THEIR CLINICAL EFFECT Short and long-pulse 1064-nm IR laser irradiations have proven effective in inducing prolonged photo-thermal biologic stimulation in living tissues. Temperatures up to 44-46°C applied for relatively short amounts of time to skin and subcutaneous tissue have proven effective in increasing pro-collagen I and III production, activating HSP-70, increasing TIMP and decreasing MMPs. All these actions constitute important factors in preventing and improving the complex biologic alterations of tissue aging. HA fillers are currently the mainstay of facial and extra-facial bio-remodelling and bio-stimulation treatments. It is well known that HA can provide a much better and more efficient bio-matrix to living cells, optimizing their overall activity. Short term 1064-nm laser-induced temperature pre-conditioning of skin and subcutaneous tissue is able to improve the biological "ground" where HA fillers are to be injected. Photo-thermal tissue "priming" will induce a better biological acceptance, integration, and long-term persistence of HA fillers, preparing cells and extracellular tissue to better interact with HA microstructure, optimizing their volumizing and bio-stimulating effects.

MARINI Leonardo PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 08:30 to 09:10 Session: RECENT UPDATES AND TRENDS IN AESTHETIC REGENERATIVE MEDICINE & SURGERY WHAT'S NEW IN ENERGY-BASED DEVICES Medical technologies continue to evolve producing surprising clinical effects on human tissues. More treatment options have become progressively available in the last few years achieving variable degrees of success in many different medical fields and particularly in Dermatology. Better and safer treatments showed to improve skin colour uniformity, textural and functional harmonization, and body contour selectively interacting with subcutaneous fat. Innovative microwave systems producing 2.45GHz emissions are able to effectively interact with tissue water and subcutaneous adipocytes through a biophysical process identified as "dielectric heating". Concentrating this form of energy at different depths can generate effective dermal tightening reactions as well as a selective redistribution of subcutaneous fat. It could be a valuable alternative for body reshaping and cellulite treatments. High-intensity focused electromagnetic technology (HIFEM) is a non-invasive treatment option used to strengthen striated muscles through secondary electric currents generated by rapidly changing magnetic fields. Secondary electric currents are responsible for selectively depolarizing motor neurons inducing muscles to contract independently to brain activity. Contraction reaches supramaximal levels since muscle fibres do not have time to relax between two consecutive stimuli. HIFEM penetrates deeply into treated tissue and affects deeper motor neurons. 15%-16% increase in abdominal muscle thickness associated to hyperplasia and hypertrophy has been observed. This strategy has been used to non-invasively improve the contour of abdominal and gluteal regions. HIFEM has been reported effective in reducing subcutaneous fat layers up to 19% while 92% increase of apoptotic index of the adipocytes has been observed in pigs 8 hours after HIFEM exposure. HIFEM can therefor set a new treatment paradigm in body reshaping. Coming to lasers and light devices, innovative fractional applications of advanced 1064-nm QS nano/picosecond systems seem to effectively contribute to achieve better and safer results in treating pigmented skin lesions and remodelling/rejuvenating the skin. Dual laser platforms able to emit long-pulse 1064-nm and 755-nm wavelengths, either independently or variably combined, seem to set a new paradigm in advanced light-assisted epilation. Ablative and non ablative RF have been able to consolidate their validity in treating a large number of skin alterations. HIFU systems have shown to tighten dermal and sub-dermal layers through controlled pinpoint thermal necrosis of target tissue even if maximum attention should be given at avoiding dangerous motor-nerve facial nerve zones. Combination strategies using innovative technologies and old time-honoured treatments can further contribute to improve achievable clinical results.

MARINI Leonardo 201EF (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: UPDATES IN VASCULAR TREATMENT RESISTANT PWS: NEW TREATMENT APPROACH Laser treatment of resistant PWS has been always a challenge even for the most advanced laser experts. Dermal textural changes induced by previous laser and light treatments can negatively interfere with effective penetration of hemoglobin-specific wavelengths into deeper dermal layers. Reduced optical density of hemoglobin pigments within pre-treated affected vessels and their deeper location within dermal structures require higher fluences and larger spot sizes. Neo-vascularization triggered by inflammatory cytokines (VEGF - ANG-TIE2) is the main culprit of post-laser PWS "recurrence" rates. Very often a sort of "stalemate" is inevitably reached where little or no progression in PWS clearing is observed in spite of innumerable laser/light treatments. Trying to move beyond this clinical stalemate by "pressing" even the most advanced and powerful conventional laser and light systems to their limits might expose patients to unnecessary complications and side effects without achieving significant clinical improvements. We thought to take advantage of non-selective ablative and non-ablative fractional technologies (Frac-Sclero) to overcome these obstacles. The rationale on which we based our innovative approach is the "normalization" of tissue treated with this kind of laser delivery systems, able to generate new extracellular matrix components as well as new nerve structures. Since a new etiology has been recently proposed to explain the development and evolution of PWSs - alteration of vessels innervation by autonomous nerve endings - providing a "normalization" of these important regulatory structures might induce a sort of permanent improvement of these complex vascular alterations. The depth of laser-induced micro thermal zones (MTZ) can be easily tailored to reach all dermal layers where abnormal vessels may be located. A spatially controlled "non-specific" micro-columnar tissue coagulation can offer the opportunity to photo-thermally destroy all microstructures within laser paths including abnormal vessels irrespective of dermal depths. This approach can also be combined with one or two passes of hemoglobin-specific laser and light sources during the same treatment session. Clinical results are very promising and possibly we have found a new strategy to safely move beyond a previously unsurpassable clinical stalemate. More studies will be necessary to validate this innovative treatment approach before giving new hope to all PWS patients.

MARINI Leonardo 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS ADVANCED PHOTO-THERMAL LASER LAYERING TECHNIQUES AND LOW CONCENTRATION TCA PEELS TISSUE PRIMING BEFORE HA INJECTION FOR STRETCHMARKS Stretchmarks are common skin abnormalities affecting both sexes and races. Their clinical and microscopic appearance reminds dermal scars with variable degree of dermal atrophy induced by stretching forces acting on weakened connective tissue as observed in puberty, pregnancy, obesity, Cushing's syndrome and prolonged corticosteroid therapies. Body builders might also develop stretchmarks as a consequence of overstretching normal skin by rapid volumetric expansion of muscle masses and intense physical excercise. Dermal cells respond to hormonal, metabolic, tensile load by specific feed-back mechanisms according to intrinsic mechano-biologic behaviours able to transduce stretching information into biochemical signals shifting synthetic activities of cytochines affecting also the extracellular matrix. Lesions evolve through various stages in time: from acute alterations, described as striae rubrae in lighter photogenetic skin individuals and striae nigrae in darker photogenetic skin patients, to mature lesions known as striae albae in fair skin phototypes and striae caerulae in darker skin phototypes. Many different invasive and non-invasive treatment options have been proposed to improve the clinical aspects of stretchmarks addressing their length, width, depth, and colour with variable degrees of success. Early lesions usually respond better than mature alterations. Combination strategies seem to induce more consistent results than single therapies. It has been proven that controlled thermal and photo-acoustic stimulation of dermal-epidermal cell populations can induce the synthesis of procollagen type III and type I, besides production of HSPs, MMPs and TIMMPs. Keratinocytes play a crucial role in enhancing collagen production by dermal fibroblasts. When properly "stressed" by superficial chemical peels, they give way to a cytochine-dependend loop of complex paracrine effects. Modern reticulated HA formulations are excellent bio-volumizing and bio-stimulating fillers which, when performed regularly, contribute to achieve a naturally balanced anti-aging effect on skin and subcutaneous tissues. The sequential combination of QS nano/picosecond 1064-nm Nd:YAG laser deep photo-acoustic toning followed by long-pulse Nd:YAG 1064-nm deep photo-thermal fibroblast bio-stimuation and, in selected cases, QS nano/picosecond 532-nm superficial photo-acustic toning, 2940-nm Er:YAG AFR and/or 1550-nm NAFR followed by an "ultrafast" 15% TCA chemical peel combined with properly diluted reticulated HA fillers have proven effective in significantly improving the clinical and functional aspects of stretchmarks during the various stages of their evolution. MARINI Leonardo 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM COMBINATION TREATMENTS FOR ACNE SCARS Acne is a very common, potentially scarring skin disease. Acne needs to be properly treated in time to prevent scar formation. When scarring is observed, strategies to improve the many different clinical aspects of this highly undesirable complication are among of the most challenging treatments a dermatologist is asked to perform. The many faces of inflammatory acne associated with the extreme variability of their clinical expressions might generate a similarly vast array of scars presenting with different characteristics in different anatomical areas. Numerous classifications of post-acne scars have been proposed to help dermatologists to properly assess them before planning appropriate treatment strategies. Classically four major types of depressed scars and two types of raised scars can be recognized. To add further complexity, every affected anatomical body area can show variable combinations of different types of scars, each with different size, depth, and thickness. All corrective strategies aim at restoring as much as possible skin colour and texture, volume, and natural tissue elasticity. Different acne scars require different corrective approaches making combination strategies the best option. Topical pharmacological/cosmeceutical treatments associated with tailored low dose p.o. isotretinoin are necessary to stabilize active inflammatory acne alterations. Low level LED photo-biomodulation, specific PDT regimes, advanced bio-photonic treatments, long pulse 1064-nm Nd:YAG photo-thermal modification of skin microbiome, ablative and non-ablative fractional lasers and RF sources can be proposed few weeks after subcision and local infiltrations of HA. Personalized low calories, lactose- and sugar-poor diets should be also implemented. Surgical excision of selected hypotrophic scars and properly positioned sub-dermal autologous dermal grafts can be also considered in specific cases. Post-treatment skin care regimes are also quite important to optimize wound healing as well as minimizing potential collateral side-effects and complications. How to choose the right timing to schedule successful combination treatment strategies is not an easy exercise. Proper training to identify and implement effective sequential treatment combinations is absolutely essential to achieve successful post-acne scar correction.

MARTIN Druanne 101A (LEVEL 1) Sunday, May 12, 2019 - from 12:30 to 13:00 Session: RISING STARS FORUM BEST PRACTICE FOR PUBLISHING A SCHOLARLY ARTICLE This presentation will provide an overview of best practices when publishing a scholarly article, including what top journals are looking for in scholarly papers, understanding open access, getting through the submission and peer review stages to acceptance, and where to find effective help as an author. Attendees will leave this session with practical guidelines to be a successful scholarly author.

MENDEZ ESPANA Mauricio 201EF (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA TOPICAL AND ORAL COMBINATION THERAPY WITH TRANEXAMIC ACID IN MELASMA TREATMENT Melasma is a pathology nowadays with a high index of incidence and prevalence, it is understood as a chronic inflammatory disease of the skin in which the patient has episodes of exacerbation and also of diminution thereof.

Today there are various treatments for melasma for its reduction, in this case tranexamic acid and its role in inhibiting prostaglandins

Methods The physiopathology that melasma has is very specific at the same time very difficult to treat where various factors are involved such as hormonal activity, UV rays, increase in actvity of tyrosinase and melanosomes formation which do not lead to this hyperpigmentation. We must always recognize the types of melasma and hyperpigmentation that we are treating, since we must distinguish between solar lentigines, vascular melasmas and different entities that cause this damage to the skin

Nowadays, the use of oral supplementation based on superoxide dismutase, as well as tranexamic acid, play an important role in the treatment thereof.

Just like we should know the different types of depigmenting groups that we found Phenols: hydroquinone, arbutines, resorcinols Carboxylic acids: tranexamic / azalaic acid Others: Kojic Acid all with some degree of action towards tyrosinase directly, others with action on copper and others with action on prostaglandins PGD2

Protocol:

650 mg tranexamic acid tablets 1 time a day orally for 4 to 6 months Tranexamic acid peeling: every 4th week Topic: Kligman formula Sunscreen orally sunscreen 4 times a day 50FPS

Results As results in the patients, there was a marked improvement of the treatment with a dual therapy, combination of treatment based on topical and oral combination of sunscreen as antioxidants and oral supplementation

MENDEZ ESPANA Mauricio 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS EFFICACY IN THE TREATMENT OF EDEMATOUS-FIBROESCLEROTIC PANICULOPATHY WITH RECOMBINANT ENZYMES BY PBSERUM Introduction Edematous-Fibroesclerotic paniculopathy (EFEP) is one of several pathologies in which we can observe in our practice and one of the main reasons also of the same As we already know well the paniculopathy is a disease which has many generation risk factors, so today we have different types of products, material and technology that is oriented towards the treatment of it, either to avoid , prevent or eliminate the disease Nowadays, the use of low molecular weight recombinant lipolytic enzymes has been very successful in the treatment of this pathology. Methods and Materials PBSerum recombinant enzymes are obtained through biotechnology where genetic material is extracted from various bacteria by means of plasmids, from which we obtain Lipase, Collagenase and Hyaluronidase. With this we will make a cocktail for its preparation combining these enzymes obtained The preparation consists basically of 4cc of NaCl 0.9% with 1cc of Lidocaine 1 or 2%, well we do the reconstitution for the application of the same product Knowing the pathophysiology of the creation of EFEP we can see how the injected low- molecular-weight enzymatic drug for the destruction of this malformed collagen, the drainage of the liquid stasis that keep patients in addition to the decrease of the adipose panniculus, given that These three sets are the factors of dermal cellulite visualization Results The protocol of performance of each session will vary between each patient, ie it is a 100% individualized treatment, the degree of improvement of the paniculopathy is very noticeable, favorable and with excellent results

MIYATA Nariaki 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES MY PEARLS IN REJUVENATION TREATMENT BY USING EBD-DEFINE THE LIMITS AND POTENTIAL Nowadays, there are various energy based devices in our aesthetic medical field. Some patients think they can rejuvenate dramatically. In reality, it's not available to achieve equivalent efficacy compared with the surgical procedure. What is actual efficacy of device treatment? Is it a magic wand? Efficacy of device treatment is tightening and remodeling dermal/ subdermal tissue. To get youthful appearance, it is not enough. We should consider about laxity, atrophy and various changes of structure with aging. To improve atrophic change of each component, it's necessary to combine other procedure such as filler and thread. We should define the limit of treatments by using devices. Then, we can find the potential. And as you know, Japanese patients are very conservative. They don't prefer to be performed invasive procedures. They hate needle puncture and high dose of fillers. Moreover, some patients demand the result that their husbands cannot notice. There are various demands and we should respond well to patients' needs. How to decrease the number of filler syringe, threads, and shots of device? I will show you my pearls of rejuvenation treatments using devices and combination procedure. MOEY Christie 201EF (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA COMBINATION TREATMENT OF 755NM ALEXANDRITE PICOSECOND LASER AND MICRONEEDLE PULSED RADIOFREQUENCY IN TREATING RECALCITRANT MELASMA Melasma is one of the major skin concerns in the Asian population. Majority of aesthetic and dermatology centres of this region manage melasma on a daily basis. Managing melasma has always been challenging. There are various treatments available with inconsistent outcomes. For the past decade, Q-Switched technology has been the treatment of choice for pigmentary disorder. Increasing the fluence or the number of passes increases the heat load in the targeted tissue resulting in enhanced efficacy but also a higher rate of complications such as post inflammatory hyperpigmentation (PIH) and hypopigmentation especially in the darker skin type (Fitzpatrick skin types III-V). 755nm Alexandrite picosecond technology with shorter pulse durations can reduce the unwanted thermal side effects, increasing the safety when dealing with darker skin types. Histologically, melasma lesions show higher degrees of ultraviolet induced damage, basal membrane disruptions as well as increase vascularity. Recent studies have highlighted the importance of reducing the vascular endothelial growth factor (VEGF) and strengthening of the basement membrane to improve treatments outcome. We explore the safety and efficacy of combining 755nm Alexandrite picosecond laser and Microneedle Pulsed Radiofrequency in treating pigmentary disorder especially recalcitrant melasma of darker skin type population.

NADELA Rosalina 201EF (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: FOCUS SESSION ON PIGMENTATION: MANAGING MELASMA CHEMICAL PEELS AND MELASMA: WHAT WORKS? Melasma appears as light to dark brown or brown-gray patches with irregular borders primarily on the face. Its pathogenesis is not fully understood but several triggers have been associated- sun exposure, family history, use of oral contraceptive peels and pregnancy. Treatment remains a challenge and the practice of chemical peels still provides a useful and effective management tool. Updates and experience on the kinds of peels safe for the Asian skintype will be presented.

NG Chau-Yee 101A (LEVEL 1) Sunday, May 12, 2019 - from 12:30 to 13:00 Session: RISING STARS FORUM VITILIGO TREATMENT: IS THERE MORE THAT WE CAN DO? Vitiligo is common, disfiguring pigment disorder that negatively affects patient's self-esteem and quality of life. The treatment of vitiligo is challenging due to the complexity course of the disease. This session will summarize recent advances in the treatment of vitiligo including medical, light devices and surgical approach.

NG Chau-Yee 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM SCAR WARS: KELOID SURGERY Keloid is the most aesthetically disfiguring and functionally debilitating form of scar that remains a clinical challenge. Conventional intralesional keloid injection can often cause stretching scars with slow improvement and some even reported worsening of keloid. This session will provide useful surgical and injection tips in the treatment of ear keloid.

NOVAKOV Aleksandra 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: ULTIMATE FEMININE REJUVENATION NON-ABLATIVE ERBIUM LASER TREATMENT FOR FEMALE SUI Background Stress urinary incontinence (SUI) is a common cause of urinary incontinence and is affecting large number of women influencing significantly their quality of life. There is a large range of therapies for SUI from lifestyle/behavioral modification to surgical interventions, and these therapies differ in terms of both effectiveness and risk. However, current treatment options raised some concerns regarding safety and efficacy and there was a quest for new treatment options. Several years ago vaginal laser therapy was offered as a minimally invasive treatment option for SUI. The purpose of this study was to evaluate long term efficacy and safety of erbium laser treatment for female stress urinary incontinence (SUI). Methods In this single center prospective study in the period from April 2014 to January 2016 we performed ErYAG laser thermo-therapy on a number of female patients having SUI. ICIQ-UI as well as ISI by Klovning were used for assessment of SUI. Patients received two laser sessions with 4-6 weeks interval. Patients' satisfaction was measured with 10 point numerical scale. Follow-ups were performed at 1, 3, 12 and 18 months. Long term follow-ups were performed via telephone interviews during which aside of ICIQ-UI and patients' satisfaction additional questionnaire was used to assess the duration of SUI improvement and patients' readiness to repeat the treatment. Adverse events were registered at every follow-up. Results 132 patients with SUI were included in this study. Average age was 50.3 yrs (range 23-75) and parity 1.9 (range 0-4). Average score on ICIQ-UI before the treatment was 11.8 and at the 3 months FU 3.7, (improvement of 8.1 point). At 3 months FU 39.2% of patients were dry and 96.9% of patients improved their ICIQ score. All reported adverse effects were mild and transient. 75% of patients have the full effect lasting at least 12 months and 24% at least 18 months. Average duration of full effect was 13.0 months. 85% of patients were not disappointed when the symptoms started to come back. 97% of patients was satisfied with treatment (average score at 18 months was 7.9/10; 68% with grades 8-10 and 41% with 10/10). 98% of patients would repeat the therapy. Conclusions Erbium laser treatment showed efficacy in improvement of female SUI with no major adverse effects noted. Patients' discomfort during the treatment was minimal and satisfaction very high.

NOVAKOV Aleksandra 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: ULTIMATE FEMININE REJUVENATION FEMININE REJUVENATION AND SAFETY OF ENERGY BASED DEVICES Background Non-surgical feminine rejuvenation is one of the fastest growing segments on the energy based devices (EBD) market offering applications in rather wide range of indications, from treatment of vaginal laxity to urinary incontinence, genitourinary syndrome of menopause, pelvic organ prolapses, lichen sclerosus and others. In spite of many clinical studies executed and published, showing good results and very low level of adverse effects, there are still a lot of doubts and criticism considering clinical evidence of efficacy and safety of these treatments. Recently FDA issued a warning to some manufacturers, healthcare providers and patients about these treatments warning them that most of claimed procedures are not yet FDA cleared as well as that these treatments could be associated with some serious side effects. In this paper we are analyzing the safety of EDB for Feminine Rejuvenation. Methods Energy based devices used for Feminine Rejuvenation are mostly lasers and radiofrequency devices, but there are also a few high intensity ultrasound devices present on this market. We analyzed the mechanisms of action of these three types of EBD, claimed depths of penetration and range of medical indications. An overview of EBD and published clinical studies is given with reported adverse effects. Also, a worldwide survey among the users of non-ablative erbium laser technology was conducted with the aim to establish the safety and efficacy of intra-vaginal use of this technology. The questionnaires asking about the number of patients treated, the adverse effects registered and the level of patients satisfactions with the treatments outcomes were distributed to the large number of users. Results More than 40 different EBD were identified to offer feminine rejuvenation applications. Just two of them have a large base of published clinical studies, next 5-6 EBD have a few clinical studies done and published, while the large majority so far doesn't have any clinical validation of their technology. Data from the published studies showed that there were no serious adverse effects reported. Also, the preliminary results of the still on-going survey of non-ablative erbium intra-vaginal laser are showing very low number of adverse effects reported and all of the reported adverse effects were mild and temporary. Conclusions The most of the EBD on the Feminine Rejuvenation market don't have clinically validated safety of their devices, however a two of them, being on the market for almost ten years and having large body of evidence in many published studies are showing very high safety profile and also very good efficacy in selected indications. PATHAK Surajit 101A (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: REGENERATIVE MEDICINE, CELL THERAPIES & MICROBIOME IMPACT OF MESENCHYMAL STEM CELLS DERIVED CULTURE MEDIUM IN SKIN CELLS AGING: AN APPROACH TO USE LABORATORY RESEARCH IN CLINICS FOR SKIN CELL REJUVENATION Stem cells in tissues typically exhibit tissue-specific differentiation patterns, and their capacity to balance quiescence with proliferative activity appears to be critical for their survival and maintenance of suitable physiological and regenerative responses. In the context of these studies, we have focused on the role of conditioned medium derived from human umbilical cord-mesenchymal stem cells in modulating the fate of skin cells to stem cell-like cells. We have recently found that this conversion of keratinocytes into stem cell-like cells is an intermittent step and the continuous treatment of these cells by conditioned medium tend to form cell strap and adipocyte lineages. Formation of collagen straps in between the cells helps to communicate with each other and to acquire specific lineage commitment. Continuous treatment of skin cells by conditioned medium traverse them towards adipocytic lineages. Complete metabolomic profiling of the conditioned medium has been achieved in our lab and probably it will help us to identify the different molecules present in conditioned medium which would pave the way through synthesize new commercial molecules may be use in reducing skin aging.

PENG Peter Hsien-Li 201EF (LEVEL 2) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: ART & SCIENCE FOR THREAD-LIFTS (II): THREADS IN COMBINATION TREATMENT THREAD LIFT AND FILLER INJECTION COMBINATION TREATMENT There are many signs of an aging face, such as volume loss, depression, wrinkles, folds, laxity, sagging, irregular pigmentations, and changes in skin texture. Many studies have shown these aging signs to be related to degenerative changes in all five layers of the face: bony remodeling, deep fat volume loss, ligament and SMAS laxity, downward repositioning of superficial fat pads, skin laxity, loss of elasticity, and dyschromia formation.

Combination treatment is one of the trend for minimal invasive approach to aging face and beutification of the face. The two major ageing components of sagging and volume deficiency can be address by threads lift and filler injection synergisticly.

In this presentation, I will focus on rational approach, sequence and techniques of thread lifting and filler injection procedures for facial rejuvenation and beautification.

PENG Peter Hsien-Li PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 08:30 to 09:10 Session: RECENT UPDATES AND TRENDS IN AESTHETIC REGENERATIVE MEDICINE & SURGERY WHAT'S NEW IN INJECTABLES Aging signs over the the face can be divided to four categories: volume loss (bone or fat) , sagging (SMAS, retaining ligaments, skin) , wrinkles (static and dynamic), and skin pigmentation changes.

Injectables have gained and maintained its popularity since its introduction more than one decade ago. Its advantages include immediate and long lasting results, minimal-invasive procedures, and minimal downtime.

There are many kinds of injectable fillers on the market, which makes their selection of high importance. Even HA products within a single brand can differ in their properties and intended indications. There are some publications about the rheologic properties of HA filler, which could be useful for clinicians who utilize this treatment method.

In recent years, injectable fillers are no longer used solely for volumization, but also for reshaping purposes, with "lifting", skin rejuvenation, and hydration effects. Myomodulation effects have also been identified recently.

In this talk, I will present updates and new advances in injectables from the last three years.

PENG Peter Hsien-Li 201EF (LEVEL 2) Sunday, May 12, 2019 - from 09:30 to 10:30 Session: EMERGING ENERGY- BASED DEVICES: PICOSECOND LASERS - WHERE ARE WE NOW COMBINED PICOSECOND 532/1064NM AND Q-SWITCHED 694NM LASER IN ASIANS Pigmented lesions are one of the most concern skin problems among Asians. One comparison study about ageing face between Japanese and French women showed that wrinkles occurred earlier in French but pigmentary changes more obviously seen in Japanese women. And the culture difference also contribute to the motivation to treat the pigmented lesions.

Besides the epidermal pigments such as freckles and solar lentigines, the dermal pigments of Ota nevus or Hori's nevus were much common in Asian population compare with Caucasians. The prevalence of melasma also more common in Asian. The Asian skin are more prone to have postinflamatory hyperpigmentation after skin inflammation such as acne , atopic dermatitis or trauma.

The pigmentary lesions response to Q-switched lasers between Caucasian and Asian have one basic difference in the view of postinflamatory hyperpigmentation rate after laser treatment.

These kinds of epidermal pigments , dermal pigments, melasma and hyperpigmentation almost always combined appear on the patient's face which made the laser treatment more difficult.

On the other side, acne is one of the most common skin diseases seen in dermatological practices all over the world. In colored populations, acne scars and pigmentary sequelae can affect more than 50% of the population.

The fractional picosecond 1064/532 nm laser may induce new collagen formation and then have rejuvenation effect which can be used for rejuvenation and treating acne scars.

In this session, I will present the clinical experience and treatment strategy by using Q-Switched Ruby and Picosecond Nd:YAG 532/1064 nm laser for pigmented lesions and acne scars treatment on Asian skin

PENG Peter Hsien-Li 102 (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: PITFALLS TO AVOID IN AESTHETIC PROCEDURES HOW TO PREVENT BIZZARE FILLER FACE: PRINCIPLE AND STRATEGY In recent years, injectables have become more and more popular around the world. According to the yearly survey of American Society for Aesthetic Plastic Surgery, botox injection is the most popular aesthetic procedure, followed by the filler injections.

Large doses of botox injection may induce a "frozen" face. In addition, different types of filler injections may lead to "bizarre overfilling filler face".

In this talk, I will present the possible causes of "bizzare overfilling filler face" and ways to prevent this kind of iatrogenic conditions.

RAVICHANDRAN Simon PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: SHOWCASE OF INJECTABLES: UPPER FACE - LIVE DEMO FOREHEAD INJECTION DEMONSTRATION Using our understanding of the anatomy of the deep and superficial forehead compartments, we can demonstrate the technique for a safe and effective forehead volumisation. The demonstration shows the technique to enter the deep fat compartments with a cannula and safely deposit volumising dermal filler.

ROJANAMATIN Jinda PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 12:00 to 13:00 Session: SHOWCASE OF INJECTABLES: MIDFACE & NOSE NASOLABIAL FOLD, NOT JUST A SIMPLE FOLD Nasolabial folds are the creases that run from the edges of the nose to the sides of the mouth. The main reason these folds appear to deepen with age is because of the loss of foundation underneath the mid-face and under- eye area, also known as the "base of the face." As the foundation beneath this mid-face area wears away, the skin in this area, particularly the cheek, begins to sag downward over the nasolabial fold, creating a shadowy effect that makes the crease more apparent. The most common factor in the deepening of nasolabial folds is age and natural foundation loss (base loss). In addition to aging, the appearance of nasolabial folds may be caused by excessive weight loss or tooth loss, which leads to bone loss. Additionally, smoking can be a major accelerant in the appearance of nasolabial folds.

SAMIZADEH Souphiyeh PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: ANATOMY FOR AESTHETIC TREATMENTS: ANALYSIS WITH TIPS & PEARLS FOR INJECTABLES AND THREADS PERIORAL AND NECK ANATOMY FOR NON-SURGICAL ENHANCEMENT AND BEAUTIFICATION Enhancement, rejuvenation and beautification of the perioral region can be very challenging. There are skeletal as well as soft tissue factors that affect the soft tissue morphology and appearance of this area. Understanding of perioral anatomy, the pattern of the vasculature, the importance of muscular balance and the local muscular integrations can aid practitioners in treatment planning and optimal treatment delivery.

SAMIZADEH Souphiyeh PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SHOWCASE OF INJECTABLES: LOWER FACE & NECK - LIVE DEMO LIVE DEMONSTRATION 2: LIPS Nonsurgical lip enhancement using dermal fillers is a very popular procedure. The trend of enlarged lips has been popularised by media and social media. The lips have considerable aesthetic and functional importance, in addition to having a complex anatomy. Serious complications including vascular compromise or occlusion leading to cutaneous necrosis and blindness can occur as the result of lip enhancement using dermal fillers. Therefore, aesthetic practitioners require an in-depth understanding of the anatomy and vasculature of the lips and the perioral area prior to providing lip enhancement using dermal fillers. Analysis of the literature revealed that the labial arteries display high variability with respect to path (distribution), presence, and location. Increasing the volume of lips through injections of dermal filler needs to be undertaken with caution, and awareness of the anatomical variation in artery location and path is a crucial concept that is mandatory knowledge when injecting the lips.

SEO Suk Bae 201EF (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 13:00 Session: EMERGING ENERGY-BASED DEVICES INTRADERMAL DELIVERY OF INJECTABLE PLLA WITH MICRONEEDLE RF FOR ACNE SCARRING Atrophic acne scarring may be one of the most stressful problems among dermatologic patients. Various treatments such as fractional laser, laser peel, chemical peels, surgical excision, dermabrasion, and tissue augmentation with fillers, have been used for the treatment of acne scarring. However, treatment of atrophic scars is not easy. Even with the all available procedures, outcomes may vary depending on patient's skin condition and physician's skill. Different treatments often come with a long down time and post inflammatory hyperpigmentation. It's hard to expect an excellent outcome every time. Needle RF has been shown to enhance collagen remodeling in the dermis. PLLA is a well known rejuvenation material. My new method is the intradermal delivery of injectable PLLA with microneedle RF. I used sonication to make the PLLA safe for injecting in the intradermal area. I also used a specially designed drug delivery instrument with needle RF. Through my presentation, I will show the excellent results of my combination treatment.

SHAH Falguni PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 09:25 to 10:30 Session: SHOWCASE OF INJECTABLES: UPPER FACE PERIORBITAL REJUVENATION BY COMBINING VARIOUS TECHNIQUES: A 'HOLISTIC' APPROACH Beauty is not just in the eyes of the beholder but also in the eyes of the holder. "Eyes' are probably the most important feature which contributes to beauty but it is also known that the "periorbital' region is where ageing initiates. Through this talk, I would want the delegates to understand, how to treat the entire area including the brows, periorbital melanosis, forehead contour and tear trough. Combining neuromodulators and hyaluronic acid (injectables), epidermal peels, "Q' switch laser and microblading of the brows and cosmeceuticals to give the desired results. Further, before the use of injectables for the tear trough, I will also stress on the need of sound knowledge of vascular anatomy, as the internal and external carotid system are connected.

SHEEN Yi-Shuan 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) MELANOMA: EPIDEMIOLOGY, DIAGNOSIS AND OUTCOMES Cutaneous melanoma is the most aggressive skin neoplasm. Once melanoma has spread, this type of cancer rapidly becomes life-threatening. The incidence of cutaneous melanoma has continuously increased during the last decade. Cutaneous melanoma is a relatively common malignancy in the Western countries, especially among populations with lighter skin color. This condition, however, seems to have a rather different disease pattern among Asians. In Caucasian populations, the major subtype of melanoma is superficial spreading melanoma. By contrast, acral melanomas, which constitute a small proportion of melanomas in Caucasians, are the most prevalent melanoma subtypes among Asians. Compared to Caucasians, the melanomas of the Taiwanese patients were usually diagnosed at a late stage and resulted in a lower survival rate. Due to better understanding and higher awareness of both patients and physicians, the survival rates of melanoma patients in Taiwan have improved dramatically in the last 40 years. Generally, approximately 70% of melanomas are diagnosed using clinical inspection by a dermatologist; with dermoscopy, this detection proportion can be increased to up to 90%. After the histopathological diagnosis of an invasive melanoma is made, examination of the regional lymph-node basin should be done. In case of any evidence for metastasis, radiographic imaging should be done to exclude distant metastatic spread. Melanoma among Asians remains poorly understood. Our studies represent epidemiologic and clinical features of Taiwan and there is a clear distinction in the clinical patterns between Asians and Whites.

SOFRA Xanya 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING SEXUAL ANTI-AGING: SAFE METHODS TO BOOST ENERGY AND SEXUAL PERFORMANCE IN OLD AGE Aging is associated with a number of medical conditions likely to impair sexual performance. Recent research indicates that only 56% of married women older than 60 (compared to 75% of men) are sexually active. Aging is associated with decreased metabolism, increased visceral fat deposits, hair loss, decreased mobility, increased incidence of body aches and impaired self-confidence leading to marital dissatisfaction, conflicts or apathy. The decline in thyroid Hormones results in Depressive symptoms that add on to low self-esteem, self-blame and discontent.

Sexual Dysfunction is quite prominent among Diabetics. Owiredu WCBA et al (2017) examined 130 diabetic males with impotence and premature ejaculation and 116 Diabetic females who displayed non sexuality or avoidance and infrequency. The study's conclusion was that ageing and longer time of the disease in Diabetics reduces sexual quality of life.

The decrease in testosterone levels is also one of the causes eectile dysfunction and low sexual desire. No association between was found for a testosterone/estradiol imbalance affecting erectile function and sexual desire. (Castello-Porcar AM, Martinez-Jabaloyas JM, (2016). Therefore, estrodiol may not be a testing necessity in sexual aging

Vaginal Rejuvenation. In women estrogen decline leads to loss of subcutaneous tissue from the mons pubis, atrophy of labia majora and shortening and loss of elasticity of the vaginal barrel. Collagen and elastic content decreases by 30% to 50%. The reduction of vaginal thickness of the epithelium from 8-10 layers to 3-4 leads to bleeding and burning sensations during intercourse. Loss in the Lactobacillus species and lactic acid and increased vaginal pH affect the microbial population leading to increased bacterial infections. Laser and radiofrequency methods of vaginal rejuvenation create scar tissue ultimately reducing sensation for women. A recent clinical study with 25 subjects who received vaginal rejuvenation treatment with a non trauma signalling technology combining both motor nerve signalling and skin repair signalling reports increased sexual contact, increased sexual desire, sensation and satisfaction during intercourse and significantly increased frequency from an average of once in three months to once weekly. Additionally women reported a significant reduction in bacterial infections.

Another clinical study with 12 subjects indicated an increase in both sexual desire and activity and an ability to sustain sexual intercourse longer with men who were subjected to two hours of effortless exercise three times a week (Barnard, 2013). There is substantial evidence from a number of studies including a study with 350 subjects that the technology separates RBCs acting like a natural blood thinner (like a natural Viagra) in both men and women ( and Weiss, 2010). Increased blood flow signifies better transport of oxygen, antibodies and waste products to the liver and kidneys serving as a crucial component of Lymphatic Drainage Overall, the technology is designed to act as a very powerful detoxification method. A number of studies (Dacu al 2016, Textbook of Modern Toxicology Hodgson 2004)) have concluded that toxicity interferes with the entire endocrinological system, compromising metabolism and sex hormone synthesis. Hence the increased sexuality as the result of detoxification

Physical activity maintained throughout life is associated with lower incidence and prevalence of chronic diseases such as cancer, diabetes and cardiovascular and coronary heart diseases [Myers et al 2002, Booth at al. 2000]. Recent studies suggest that physical exercise also enhances cognitive functions and protects against dementia (Larson et al 2004 and others). However older individuals have difficulty exercising due to weight, muscle and nerve pains or disinterest. Effortless Exercise motor nerve resonance inducing endorphin & hormone release that balances endocrinological system and elevates mood. Technology detoxes and separates RBCs while utilizing fat as an energy source to build muscle mass. An experimental study with 19 subjects receiving 12 treatments (Ballot and Weiss 2012) reported statistically significant reduction of visceral fat, muscle mass increase and increased concentrations of T3 and DHEA. Subjects reported a boost of energy and sexuality and less susceptibility to common colds after treatment. A follow up study with 8 subjects reported a statistically significant increase in Testosterone concentrations. Testosterone decline has been associated with depressed mood which is a suppressant of sexual appetite

A recent study by Dr Nuris Lampe on 14 diabetic neuropathy patients using signalling technology reported a 98% of pain relief and increased foot mobiity. Another recent clinical study by Elaine Wong revealed hair growth on two aged patients who received signalling technology on areas of hair loss

The Psychological component cannot be neglected. Effortless exercise can be combined with natural rejuvenation methods and short term psychotherapy that focus on: 1. Introducing the individual to himself / herself. Approving himself / herself appreciating his /her strengths while accepting his / her weaknesses 2. Freeing oneself from the stickiness of the past, putting his / her attachments, resentments and losses in his / her museam and moving on 3. Learning how to turn adversity into advantage by looking out for opportunities and grabbing them as they come. 4. Utilize his / her character flaws in a productive manner and to his / her advantage. Ex. Utilize the Obsessive compulsive Disorder that compels one to wash their hands for over 5 hours and translate neurosis into work ethic thus fulfilling work duties in the most thorough and detail oriented manner that can ensure professional success (without sticking on each detail)

SOFRA Xanya 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING HEALTH AND FITNESS BY COMBATING HORMONAL DECLINE, COMPROMISED METABOLISM, AND TOXICITY We age because the biochemical processes that sustain life generate toxins that cause damage which accumulates despite endogenous repair. Toxicity interferes with the entire endocrinological system leading to a resistance in losing weight. (Dacu al 2016, Textbook of Modern Toxicology Hodgson 2004.) The decline of metabolic hormones in ageing causes a reduced resting metabolic rate (calories burned when the body is at rest), leading to weight gain and low-grade inflammation.

Sex hormones strongly influence body fat distribution and adipocyte differentiation. Estrogens and testosterone differentially affect adipocyte physiology leading to Obesity-associated hypotestosteronemia in males. (Liziano and Guzman 2014) Estrogens deficiency enhances metabolic dysfunction in women. (Carr 2003S)

Compromised metabolism results in increased visceral deposits signifying elevated toxicity since adipocytes store toxins. Blood carrying visceral fat cells, stuffed with excess triglycerides, take free fatty acids into the liver, pancreas & other organs causing dysfunction, impairing regulation of insulin & cholesterol. Fatty liver is enlarged by visceral fat invading it and rendering it ineffective in tis normal functioning.

A recent systematic review and meta-analysis including 2.8 million people and 270,000 deaths reported increased overall mortality only in those with extreme obesity (BMI > 35 kg m−2, hazard ratio (HR) 1.29, 95% confidence interval (Fui et al, 2014)

The deleterious effects of obesity can be counterbalanced by exercise. C-reactive protein concentration for participants who engaged in physical activity were 0.53 (95% confidence interval =0.40-0.71) for vigorous exercise, 0.85 (0.70-1.02) for moderate exercise, & 0.98 (0.78-1.23) for light exercise, during a 30 day period, compared with participants who did not engage in any leisure-time physical activity.

However, most aged and overweight individuals have difficulty exercising or cannot exercise due to medical reasons. Clinical studies conducted under medical supervision (Pollock, Badami, Barnard, Lampe, Balot, Weiss and others) have shown that a London University technology inducing effortless exercise serves as a solution for such individuals. Effortless exercise offers an 8 seconds full contraction that involves the co-coordination of large muscle groups (e.g. abdomen, buttocks, chest, legs, arms) working together, simulating strenuous exercise. This is a very different process from muscle stimulators' multiple bursts of electrical current that continuously twitch uncoordinated individual muscles. Muscle stimulators have been widely criticized by research for increased muscle cells apoptosis as a result of trapped calcium resulting to a pause in ATP production. (Pinton et al 2008 and others)

Goldspink et al (1991) found that effortless exercise technology produces rapid hypertrophy, reflecting changes in gene expression (detected by analysing the RNA). This expression involved skeletal genes that are associated with overload, stretch and physical exercise implying a kinsmanship between effortless exercise and physical activity. A study with 8 subjects receiving 6 treatments of effortless exercise within 3 weeks showed a significant decrease in BMI, body fat and an increase in muscle mass when compared to six weeks of physical exercise (Weiss, 2011). A follow up study (Ballot and Weiss 2012) that offered 12 effortless exercise treatments to 19 subjects found a statistically significant reduction of visceral and subcutaneous fat and a statistically significant increase of muscle mass in magnetic resonance imaging slides (MRIs).

Effortless exercise was originally built in London University in 1994 for Multiple Sclerosis after a 17 years research by the co-inventor of the first Pacemaker. Since then there have 24 upgrades, with the latest upgrade (Virtual Gym Unique II) being launched in August 2018. During treatment, voltage drives motor nerve blueprint copies through the skin to the central nervous system (a process similar to needle-less vaccination). Motor nerve excitation spreads throughout the CNS (like a domino effect), reaching the brain and inducing the release of hormones whose metabolites utilize adipocyte contents as an energy source to increase muscle mass. Hormonal concentration increases (T3, IGF-1, DHEA and Testosterone) have been shown by a number of medical doctors conducting clinical studies (Pollock, Barnard, Lampe, Gizerski, Badami, Ali, and others).

In a nutshell the crucial requirements for effortless exercise to work are: 1. Signalling compatibility with motor nerve signals. CNS discards all signals that are incompatible with its signalling network. 2. Resonance between incoming motor nerve blueprint signals and biological motor nerve signals resulting in lightening waves of motor nerve signals that spread via the CNS network reaching the brain to trigger hormonal release.

The technology employs original handmade mechanisms that safely reach visceral fat while inducing a powerful detoxification by specific complex signalling waveforms that target the lymphatic system. Lymphatic drainage is further reinforced by the experimentally observed phenomenon of RBC's separation (RBCs carry waste products to the liver and kidneys for their eventual excretion). The additional benefit of blood separation results in a more efficient oxygen and nutrients transport for cellular nourishment and survival, as well as antibodies to their sites of action, ultimately strengthening the immune system.

STANKOVIC Nenad 201EF (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ART & SCIENCE FOR THREAD-LIFT (I) COMPLICATIONS FROM ABSORBABLE THREADS FOLLOWING THREAD-LIFT FOR FACIAL REJUVENATION Nowadays, thread lifting is favoured as a minimally invasive alternative to surgical lifting. Absorbable suspension sutures are the first minimally invasive, entirely absorbable treatment option for tissue repositioning and recontouring that can be performed under local anaesthesia and which demands very little patient downtime. But some complications are reported and include thread disruption, thread migration, cutaneous exposure, and skin dimpling. Thread removal and reimplantation of additional threads was occasionally required.

STANKOVIC Nenad 201EF (LEVEL 2) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: ART & SCIENCE FOR THREAD-LIFT (I) ANATOMIC AND MECHANICAL CONSIDERATIONS IN FACIAL THREAD-LIFT WITH ABSORBABLE THREADS

The aging process often affects the face in a predictable way. The changes occur in every tissue layer from the skin to the bony skeletal support. It can vary depending on a person's ethnicity and a variety of other intrinsic and extrinsic factors such as photoaging, smoking, and genetics. Several predicable changes to the midface occur during the aging process. Speciﬕcally, the lower eyelid cheek junction changes as the midface begins to descend and the lower lid structures stretch and weaken. The exposure of the infraorbital rim is a hallmark of this process. While conventional nonsurgical procedures are not sufﬕcient for improving excess skin or decreased laxity, direct surgical lifting provides a sufﬕcient mechanical force for instant and durable lifting effects. However, surgical lifting requires extensive and meticulous dissection of the superﬕcial muscular aponeurotic system and involves a signiﬕcant recovery period. Various modiﬕcations of the technique have been introduced to simplify the procedure for both patient and the practitioner. Nowadays, thread lifting is favoured as a minimally invasive alternative to surgical lifting. Absorbable suspension sutures are the first minimally invasive, entirely absorbable treatment option for tissue repositioning and recontouring that can be performed under local anaesthesia and which demands very little patient downtime When choosing an appropriate thread material, the following qualities are decisive: enough tensile strength for tissue anchorage and durability.

STANKOVIC Nenad 102 (LEVEL 1) Saturday, May 11, 2019 - from 17:30 to 18:00 Session: PATIENT MANAGEMENT HOW CAN WE IMPROVE CONSULTATION TECHNIQUE WITH NLP (NEURO-LINGUISTIC PROGRAMMING) ? How can we improve consultation technique with NLP (Neuro-Linguistic Programming)?

The consultation remains central to medical practice. In couple of first minutes we need to develop sufficient rapport to delve into another person's world, understand their viewpoint and define not only their problem but bring our expertise to bear in agreeing a management plan acceptable to both parties. This is a big ask, requiring considerable skill to do well. We rely on our natural ability to communicate and hope that medical doctors have a natural talent to do it. Yet most of us are surrounded in our own lives by examples of poor communication, whether it is with patients, staff, juniors, friends, spouses, children, other relatives, or neighbors.

Human communication is straightforward only when others think like us, and we often assume they do. In reality we think as differently inside our minds, as we look in appearance on the outside. All the factors that affect the way we look (age, sex, genetics, health, history, culture, beliefs and mood) affect the way we think.

Neurolinguistic programming (NLP) was born from observing the structure of human thinking and communication in therapeutic situations, providing great insight into this process and how change can be most economically achieved.

STANKOVIC Nenad 102 (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: BODY CONTOURING CURRENT & FUTURE TRENDS CLINICAL BENEFIT OF USING A MULTIFRACTIONAL ER: YAG LASER COMBINED WITH A 15% TCA PLUS AHAS FOR THE TREATMENT OF STRIAE DISTENSAE Clinical benefit of using a multifractional Er:YAG laser combined with a 15% TCA plus AHAs for the treatment of striae distensae

Introduction: Striae distensae are an extremely common, therapeutically challenging form of dermal scarring. Risk factors have been reported but much remains to be understood about their epidemiology, diagnosis and treatment. Striae distensae occur in pregnancy, puberty and obesity as well as in numerous medical conditions and following therapeutic interventions. Proposed etiological mechanisms relate to hormones, physical stretch and structural alterations to the integument. Striae distensae affects patients both physically and psychologically. Various modalities have been used for the treatment of post-acne scarring like topical creams, chemical peels, microdermabrasion, fractional and non-fractional lasers. The possibility to perform multifractional ablation of the epidermis before applying a mixture of 15% TCA (Trichloroacetic acid) and AHAs (Alpha hydroxy acids) on Striae distensae to induce cosmetic improvement, was evaluated.

Objective: The aim of this study was to evaluate the efficacy and safety of using a multifractional Er:YAG laser combined with a 15% TCA plus AHAs in for the treatment of Striae distensae

Materials & Methods: Multifractional ablation of the epidermis into the superficial dermis by Er:YAG laser until points of blood are seen. This technology induces also the generation of acoustic waves to stimulate tissue regeneration. Immediately after 1 coat of the peeling TCA 15% plus AHAs is applied, uniform frosting appears. After that, an anti-inflammatory and healing cream is applied on the treated area. Four sessions are performed with 4 weeks in between each session. Improvement was assessed by the physician using photographs before and after treatment, and patient feedback after the fourth treatment.

Results: Based on the analysis the before/after photographs, there was significant improvement in superficial and moderately deep Striae distensae as well as improvement in skin texture. Prolonged but transient redness was observed in most patients. However, no significant adverse effects such as prolonged pigmentary changes or scarring were noted.

Conclusions: Treatment of Striae distensae with the Multifractional ablation of the epidermis into the superficial dermis using Er:YAG laser and 15% TCA plus AHAs is a safe, minimally invasive, efficacious, and effective office procedure with minimal downtime. STANKOVIC Nenad 101A (LEVEL 1) Sunday, May 12, 2019 - from 17:30 to 18:00 Session: PRACTICE MARKETING 9 WAYS TO MARKET YOUR MEDICAL PRACTICE WITH SOCIAL MEDIA: A DOCTOR'S GUIDE Social media can be intimidating to many physicians. But the truth is, it can also be a huge, cheap marketing asset. Consider that just having a Facebook and Instagram profile for your practice can improve your search results online. Social media is also ripe with opportunity for patient engagement and spreading the word about your medical practice online. Whether you're starting a new practice or just looking to expand your patient base, social media should be part of your practice marketing strategy.

SUN Pei-Lun 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 08:30 to 10:30 Session: UPDATES IN MOLECULAR DIAGNOSIS AND NON-INVASIVE SKIN DIAGNOSTIC TOOLS APPLICATION OF MOLECULAR TOOLS IN CLINICAL MYCOLOGY Polymerase chain reaction (PCR)-based techniques are the main molecular tools used in the diagnosis of fungal infections. When combined with DNA sequencing, it can also be used for the identification of the fungal pathogen. Rapid diagnosis of fungal infection can be achieved by direct extraction of fungal DNA from clinical sample followed by PCR alone or combined with sequencing. For cases with only pathological diagnosis, the DNA also can be extracted from formalin-fixed and paraffin-embedded tissue to identify the causative agents. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-ToF MS) is a proteomic-based identification tool that is now widely used in the identification of bacteria and yeasts. More and more reports support its application in the identification of moulds. Molecular tools also can be applied in epidemiology to trace the infection source and investigate outbreaks.

SUN Pei-Lun 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: FROM BENCH TO BEDSIDE (LECTURES IN MANDARIN) FUNGAL BARCODING: THE ROLE OF MOLECULAR IDENTIFICATION OF FUNGAL PATHOGENS IN CLINICAL PRACTICE Along with the extensive use of molecular phylogeny analysis, fungal taxonomy has undergone major changes in recent years, moving towards a polyphasic approach that combines mycology, ecology, and phylogenetic characteristics. The identification of pathogenic fungi has also evolved from using morphological and biological features to methods combining DNA sequence information. In this talk, I will share how does this work in clinical settings.

SUN Pei-Lun 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SKIN INFECTIION AND SEXUALLY TRANSMITTED DISEASES (LECTURES IN MANDARIN) UPDATES IN THE SKIN MYCOLOGY In this presentation, several topics will be addressed: (1) zoonotic dermatophytosis (2) subcutaneous fungal infections (3)" tinea incognito"—steroid modified tinea, and (4) tinea capitis—an unsolved problem. The epidemiology of fungal infections in Taiwan is difficult to figure out because the fungal pathogens are not properly isolated and identified in most cases. A TDA-based initiative on this issue is urgently needed.

TING Sze-Wen 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SKIN INFECTIION AND SEXUALLY TRANSMITTED DISEASES (LECTURES IN MANDARIN) RE-EMERGING SYPHILIS: AN OLD BUT CLOSE FRIEND Syphilis is a sexually transmitted disease caused by the spirochaete Treponema pallidum subspecies pallidum. It was first described in 1905 and still affects at least 11 million people worldwide every year. It can be transmitted by oral, anal and genital sexual contact, vertically during pregnancy or by blood transfusion.

Due to the inability to culture the organism and the limitations of direct microscopy, serologic testing is the mainstay of laboratory diagnosis. Although the typical clinical presentation is well known to many dermatologists, there is still great variety of clinical manifestation especially in immunocompromised patients. Combination of highly suspicion to subtle clinical signs and proper interpretation of serology test result is crucial to correct diagnosis of syphilis and prevention of further spreading.

As for treatment, penicillin G is considered the first-line therapy for all stages of syphilis. Alternative regimen is only reserved for non-pregnant patients with no evidence of central nervous system involvement. For pregnant women or patients with neurosyphilis, penicillin G remains the only effective treatment option.

In this section, we will review the clinical manifestation of syphilis, including typical and atypical ones, important diseases to be listed on the differential diagnosis and pitfalls in the diagnosis and management. Hopefully to refresh our skills in defeating this re-emerging treat to public health.

TSAI Ren-Yeu 201EF (LEVEL 2) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: HAIR & NAILS FORUM: LATEST UPDATES IN HAIR REGENERATION & NAIL DISEASES ANDROGENIC ALOPECIA: UPDATES Topical minoxidil and oral finasteride are the two only FDA-approved drugs for the treatment of androgenetic alopecia. A new oral medication-Dutasteride was approved by Korea and Japan FDA 9 and 3 years ago respectively. This dual 5-alpha reductase inhibitor was approved by Taiwan FDA in November 2017. From our preliminary clinical experience, outcomes in terms of clinical efficacy and side effects are compatible with reports in the literature. Another emerging treatment is platelet rich plasma, which is promising but in need of more clinical evidence.

TSAI Ren-Yeu 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: NEW INSIGHT AND DISCOVERY IN CLINICAL PRACTICES (LECTURES IN MANDARIN) WHY I DON'T DO ND-YAG LASER SWEEPING The reasons that I do not perform laser toning are: 1. Lack of a strong theoretical basis 2. Non-specific therapy 3. Modest clinical outcomes 4. Many patients who have presented with complications

TSAI Ya-Chu 201ABC (LEVEL 2) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: PSORIASIS PSORIASIS TREATMENT: INTERLEUKIN AND ANTI-INTERLEUKIN Psoriasis is a chronic immune-mediated inflammatory disease. Anti-interleukin (IL) therapies have emerged as a major treatment for patients with moderate-to-severe psoriasis. Currently, IL-17/IL-23 pathways are identified as playing the key roles in the immunopathogenesis of psoriasis, but numerous other cytokines are also involved in the pathway. We reviewed the up-to-date results of pivotal clinical trials targeting the interleukins used for the treatment of psoriasis, including IL-1, IL-2, IL-6, IL-8, IL-10, IL-12, IL-17, IL-20, IL-22, IL-23, IL-36 and bispecific biologics IL-17A/tumor necrosis factor alpha (TNF-a). Cytokines involved in the circuits of psoriasis inflammation without ongoing clinical trials are also mentioned (IL-9, IL-13, IL-15, IL-16, IL-18, IL-19, IL-21, IL-24, IL-27, IL-33, IL-35, IL-37, and IL-38). TSENG Fang-Wen PLENARY HALL (LEVEL 3) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: MALE VS FEMALE: BEAUTIFICATION BETWEEN MALE AND FEMALE IN 21ST CENTURY ( LIVE SHOW) PRACTICAL PEARLS ON HOW TO MAKE MALE PATIENTS MORE HANDSOME (INSTEAD OF PRETTIER) WITH INJECTABLES Although the number of male patients is rising in the aesthetic clinics, physicians are less familiar with the needs of men. The preferred image of men is different from women, the facial curves should be more angulated and not as rounded. That's why TSENGit's easier Fang-Wento rejuvenate female patients with volumizing fillers while male patients can PLENARYbe easily over-filled. HALL The (LEVEL speaker will3) Saturday,share with the May audience 11, 2019 in each - fromareas of11:00 men's to face 13:00 how to inject to strengthen/ maintain the masculine features. Session: MALE VS FEMALE: BEAUTIFICATION BETWEEN MALE AND FEMALE IN 21ST CENTURY ( LIVE TSENG Fang-Wen SHOW) PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 09:25 to 10:30 PRACTICAL PEARLS ON HOW TO MAKE MALE PATIENTS MORE HANDSOME (INSTEAD OF PRETTIER) WITHSession: INJECTABLES SHOWCASE OF INJECTABLES: UPPER FACE Although the number of male patients is rising in the aesthetic clinics, physicians are less familiar with the needs of men. The FILLERpreferred CONTOURING image of men is FORdifferent FOREHEADS from women, OF the DIFFERENT facial curves shouldSHAPES be more angulated and not as rounded. That's why it's easier to rejuvenate female patients with volumizing fillers while male patients can be easily over-filled. The speaker will shareForehead with theaugmentation audience in is each one areas of the of men'smost commonlyface how to performed inject to strengthen/ filler procedures maintain in the Asia, masculine although features. it had long been overlooked in western culture until recently. However there is still a paucity of discussions in forehead filler contouring in congresses and literatures. Forehead filler contouring is effective in both rejuvenation and beautification of the patients. A successful treatment starts with a proper aesthetic design, tailored to the needs of each individual patient who may present different shapes of the forehead. The speaker will share with the audience how to treat foreheads of different width, different TSENG Fang-Wen PLENARY HALL (LEVEL 3) Sunday,prominences May of bony 12, landmarks,2019 - from different 09:25 distribution to 10:30 of depressions, also take into consideration the sexual dimorphism. Session: SHOWCASE OF INJECTABLES: UPPER FACE TSENG Fang-Wen PLENARY HALL (LEVEL 3) FILLERSunday, CONTOURING May 12, 2019 FOR - from FOREHEADS 16:30 to 18:00OF DIFFERENT SHAPES Session:Forehead augmentation is one of the most commonly performed filler procedures in Asia, although it had long been SHOWCASEoverlooked in western OF INJECTABLES: culture until recently. LOWER However FACE there &is NECKstill a paucity - LIVE of DEMOdiscussions in forehead filler contouring in congresses and literatures. Forehead filler contouring is effective in both rejuvenation and beautification of the patients. A HORIZONTALsuccessful treatment NECK starts WRINKLES: with a proper AN aestheticEFFECTIVE design, & DURABLEtailored to the SOLUTION needs of each individual patient who may present different shapes of the forehead. The speaker will share with the audience how to treat foreheads of different width, different prominencesThe speaker willof bony demonstrate landmarks, how different to treat distributionthe horizontal of depressions, neck wrinkles. also take into consideration the sexual dimorphism.

TSENG Han-Chi TSENG Fang-Wen 103PLENARY (MANDARIN) HALL (LEVEL 1)3) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SHOWCASESKIN INFECTIION OF INJECTABLES: AND SEXUALLY LOWER TRANSMITTED FACE & NECK DISEASES - LIVE DEMO(LECTURES IN MANDARIN) HORIZONTALCUTANEOUS PROTOTHECOSISNECK WRINKLES: AN EFFECTIVE & DURABLE SOLUTION TheProtothecosis speaker will is andemonstrate uncommon how infection to treat caused the horizontal by the achlorophyllic neck wrinkles. algae found more commonly in tropical areas. Only a limited number of cases have been reported. We retrospectively identified 20 pathology-confirmed cases of cutaneous protothecosis based on skin biopsies in two tertiary medical centres in Taiwan from 1997 to 2015. The age of the patients at the time of diagnosis ranged from 48 to 85 years (mean age of 74 years). All lesions developed on the limbs. Twelve (60%) patients had adrenal insufficiency, but no patients had active malignancy at diagnosis. Interestingly, four TSENG Han-Chi 103 (MANDARIN) (LEVEL 1) Sunday,(20%) patients May had 12, concurrent 2019 - fromscabies 16:30 infestation. to 18:00 Clinically, most lesions were erythematous plaques studded with punctate ulcers. Nineteen (95%) cases were successfully treated with itraconazole for 14-148 days with only one case of recurrence. Concomitant scabies should be suspected if pruritus is recalcitrant despite itraconazole treatment. Session:Conclusion Despite its rarity, cutaneous protothecosis has become more significant due to an increased prevalence of SKINimmunocompromised INFECTIION individuals. AND SEXUALLY Steroid overuse TRANSMITTED or iatrogenic adrenalDISEASES insufficiency (LECTURES predisposes IN individualsMANDARIN) to high risk infections. Neglecting the disease leads to a chronic and incurable state. Protothecosis should be suspected in chronic CUTANEOUSeczematous and PROTOTHECOSIS ulcerative plaques on the limbs refractory to conventional antibacterial and antiviral treatments, especially in patients with adrenal insufficiency. Clinical suspicion should be confirmed by skin biopsies, and confirmed cases can be Protothecosis is an uncommon infection caused by the achlorophyllic algae found more commonly in successfully treated with itraconazole. tropical areas. Only a limited number of cases have been reported. We retrospectively identified 20 pathology-confirmed cases of cutaneous protothecosis based on skin biopsies in two tertiary medical centres in Taiwan from 1997 to 2015. The age of the patients at the time of diagnosis ranged from 48 to 85 years (mean age of 74 years). All lesions developed on the limbs. Twelve (60%) patients had adrenal insufficiency, but no patients had active malignancy at diagnosis. Interestingly, four (20%) patients had concurrent scabies infestation. Clinically, most lesions were erythematous plaques studded with punctate ulcers. Nineteen (95%) cases were successfully treated with itraconazole for 14-148 days with only one case of recurrence. Concomitant scabies should be suspected if pruritus is recalcitrant despite itraconazole treatment. Conclusion Despite its rarity, cutaneous protothecosis has become more significant due to an increased prevalence of immunocompromised individuals. Steroid overuse or iatrogenic adrenal insufficiency predisposes individuals to high risk infections. Neglecting the disease leads to a chronic and incurable state. Protothecosis should be suspected in chronic eczematous and ulcerative plaques on the limbs refractory to conventional antibacterial and antiviral treatments, especially in patients with adrenal insufficiency. Clinical suspicion should be confirmed by skin biopsies, and confirmed cases can be successfully treated with itraconazole. TSENG Yu-Ju 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SKIN INFECTIION AND SEXUALLY TRANSMITTED DISEASES (LECTURES IN MANDARIN) CUTANEOUS NONTUBERCULOUS MYCOBACTERIAL INFECTIONS Non-tuberculous mycobacteria(NTM) is a group of bacilli other than Mycobacterium tuberculosis or Mycobacterium leprae, which resides in a variety of environmental habitats including water, soil, and drinking water supplying systems. Cutaneous NTM infection is rare but it often challenges the physicians because of the diversity of cutaneous manifestations. The aim of this talk is to provide you a brief review on cutaneous NTM infection and to update you about what's new in managing cutaneous NTM infection.

TU Wei-Ting 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 15:00 to 16:00 Session: UPDATES IN GENODERMATOSES (LECTURES IN MANDARIN) DIAGNOSIS OF INHERITED EPIDERMOLYSIS BULLOSA IN TAIWAN Inherited epidermolysis bullosa (EB) comprises a group of rare genetic disorders that affect approximately 500,000 people across the world and about 500 patients in Taiwan. Clinically, all forms of EB are characterized by variable degrees of trauma-induced fragility of the skin and mucosae, blister formation, and abnormal wound healing. EB is caused by mutations in at least 20 distinct genes that encode various structural and signaling proteins at the dermal-epidermal junction and within the epidermis. Due to the complex clinical manifestations and the variety of genetic mutations of EB, correct disease classification is often difficult. The genetic mutations of most Taiwanese EB patients also remain unknown, posing significant difficulty in genetic counseling and conducting clinical research. In this session, I will talk about our approach to the diagnosis of EB, including clinical evaluation and laboratory tests, as well as our current project of genotyping Taiwanese EB patients and the preliminary results.

VAN EIJK Tom PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 09:25 to 10:30 Session: SHOWCASE OF INJECTABLES: UPPER FACE FOUR DIMENSIONAL REJUVENATION OF THE LOWER EYELID USING HYALURONIC ACID Periorbital cosmetic filler injections to rejuvenate or "freshen' the appearance of the lower eyelids are popular due to the fact that the treatment is less intensive in comparison to surgical procedures. The area around the eye however seems to be one of the most challenging. Dissatisfactory results such as the Tyndall Effect are quite common due to the transparency of this thin skin. Important in understanding what the effect of the hyaluronic acid injection will be is the notion that the cosmetic/physical effect of the injection is not only depending on the gel properties but also depending on the tissue in which it is injected. When injected in sub dermal (fat) tissue, the hyaluronic acid with act as a "filler substance' hence adding volume, whereas the same gel injected in the dermis will increase the stiffness of the skin as in the Fern Pattern Technique. Furthermore, dermal injections of hyaluronic acid will cause collagen formation. It is suggested to both fill underneath the skin and repeat these intradermal injections after a few months in order to allow the fibroblasts to produce collagen in order to enhance the outcome of the next intradermal treatment.

VAN EIJK Tom PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: SHOWCASE OF INJECTABLES: UPPER FACE - LIVE DEMO "HOW DO YOU TREAT A ...?"; CAUSE AND EFFECT, DIAGNOSE BEFORE TREATMENT, ANALYSIS BEFORE INJECTING. Ever so often aesthetic treatments tend to be categorized by the anatomical zone which is addressed ("How do you treat a frown?"). In the process of training injectors this doesn't increase the understanding of the biological phenomena indicative of aging nor the understanding of logical therapies to deal with them. VAN EIJK Tom 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM NON-SURGICAL IMPROVEMENT OF CLEFT LIP SCARS; SUBCISION-ISOLATING-FILLING-STRENGTHENING

Scars are characterized by variation in tissue strength, making them distinctive within normal tissue. In exploring ways to improve the aesthetics of scars dermal fillers can play an important role. The various properties of hyaluronic acid enable us to use this gel in several ways within one patient, within one scar.

VIZINTIN Zdenko 102 (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 13:00

Session: ULTIMATE FEMININE REJUVENATION

FEMININE REJUVENATION AND SAFETY OF ENERGY BASED DEVICES Background Non-surgical feminine rejuvenation is one of the fastest growing segments on the energy based devices (EBD) market offering applications in rather wide range of indications, from treatment of vaginal laxity to urinary incontinence, genitourinary syndrome of menopause, pelvic organ prolapses, lichen sclerosus and others. In spite of many clinical studies executed and published, showing good results and very low level of adverse effects, there are still a lot of doubts and criticism considering clinical evidence of efficacy and safety of these treatments. Recently FDA issued a warning to some manufacturers, healthcare providers and patients about these treatments warning them that most of claimed procedures are not yet FDA cleared as well as that these treatments could be associated with some serious side effects. In this paper we are analyzing the safety of EDB for Feminine Rejuvenation. Methods Energy based devices used for Feminine Rejuvenation are mostly lasers and radiofrequency devices, but there are also a few high intensity ultrasound devices present on this market. We analyzed the mechanisms of action of these three types of EBD, claimed depths of penetration and range of medical indications. An overview of EBD and published clinical studies is given with reported adverse effects. Also, a worldwide survey among the users of non-ablative erbium laser technology was conducted with the aim to establish the safety and efficacy of intra-vaginal use of this technology. The questionnaires asking about the number of patients treated, the adverse effects registered and the level of patients satisfactions with the treatments outcomes were distributed to the large number of users. Results More than 40 different EBD were identified to offer feminine rejuvenation applications. Just two of them have a large base of published clinical studies, next 5-6 EBD have a few clinical studies done and published, while the large majority so far doesn't have any clinical validation of their technology. Data from the published studies showed that there were no serious adverse effects reported. Also, the preliminary results of the still on-going survey of non-ablative erbium intra-vaginal laser are showing very low number of adverse effects reported and all of the reported adverse effects were mild and temporary. Conclusions The most of the EBD on the Feminine Rejuvenation market don't have clinically validated safety of their devices, however a two of them, being on the market for almost ten years and having large body of evidence in many published studies are showing very high safety profile and also very good efficacy in selected indications.

WANG Chao-Chin 201EF (LEVEL 2) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: ART & SCIENCE FOR THREAD-LIFTS (II): THREADS IN COMBINATION TREATMENT THE DUAL LIFT TECHNIQUE: RESTORING THE LOWER FACE CURVATURE IN ASIAN WITH OPTIMAL COMBINATION OF COG THREADS AND SOFT TISSUE FILLERS Knowing the ethnic differences of beauty I the key to successful facial reshaping. The author proposed the "Dual Lift Technique", which is an anatomy-based lifting procedure with optimal combination of cog threads and soft tissue fillers, for restoring the lower face curvature in young to middle aged Asian female. A step-by-step video demonstration will be presented. And the optimal indication and limitation of the procedure will also be discussed. WANG Yen-Jen 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: UPDATES IN THE MANAGEMENT OF SKIN MALIGNANCY (LECTURES IN MANDARIN) COMBINE NEGATIVE PRESSURE WOUND THERAPY AND EPIDERMAL GRAFTING FOR WOUNDS AFTER EXCISION OF ACRAL MELANOMA After excision of acral melanoma, a large and deep wound is left. Reconstruction with flap and/or graft right after the surgery is often the standard of treatment. However, a bulky flap can impair walking and other functions; grafts can only be applied on non-weight bearing area and eventually leave a hyperpigmented arophic scar. Patients needs to be admitted for at least 2 weeks and the scars are cosmetically undesirable. In our practice, after acral melanoma removed by slow Mohs micrographic surgery, we covered the wound with an artificial dermis. Negative pressure wound therapy(NPWT) proceeds after removal of artificial dermis and full granulation tissue growth often takes place after one month of NPWT. Epidermal grafts harvested from the thigh were transferred onto the wound and fixed with NPWT for another 2 weeks. Complete epithelialization occurs 1 month after epidermal grafting. The foot contour was well preserved; scars are both functionally and cometically excellent.

WANG Jen-Yu 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 08:30 to 10:30 Session: UPDATES IN MOLECULAR DIAGNOSIS AND NON-INVASIVE SKIN DIAGNOSTIC TOOLS APPLICATION OF ULTRASOUND IN DERMATOLOGY For lesions deep in the dermis, subcutis, fascia, muscle, and periosteum level, ultrasound imaging would help evaluating the structure, vasculature, and size of the lesion. This non-invasive imaging modality provides relevant insights to the diagnosis of lesions, and assists the therapeutic/cosmetic/surgical procedures.

WANG Jann-Yuan 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SKIN INFECTIION AND SEXUALLY TRANSMITTED DISEASES (LECTURES IN MANDARIN) LATENT TB PROPHYLAXIS Patients under biological agents, especially TNF-alpha blockers, have a significantly higher risk of developing active TB (both pulmonary and extra-pulmonary diseases). With modern rifapentine-based regimen consisting of weekly high-dose (15mg/kg/dose) isoniazid and rifapentine for 12 doses (3HP), the duration of treatment can be shorted into less than 3 months. Evidences so far show that 3HP have a high completion rate (89.4%), a lower hepatotoxicity risk (1.5%), but a high risk of flu-like symptoms (40.9%) and systemic drug reaction (3.8%).

WEI Lin-Hung 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SKIN INFECTIION AND SEXUALLY TRANSMITTED DISEASES (LECTURES IN MANDARIN) HPV VACCINATION PROGRAM Cervical cancer is the third most common cause of cancer in women around the world and remains the greatest cause of age-weighted years of life lost in the developing world. In Taiwan, statistics published by the Ministry of Health and Welfare indicate that cervical cancer is the fourth most common cancer among women, with over 4,000 suffering from the disease each year. Human Papilloma Virus (HPV) infection is the most prevalent sexually transmitted infection worldwide, and persistent HPV infection would lead to cervical cancer. Two HPV serotypes, HPV- 16 and HPV-18, are found in nearly 70 % of cervical cancers. Prophylactic HPV vaccines have been available since 2006 and have shown 90 % efficacy in preventing HPV type 16- and 18-associated high-grade cervical lesions. Despite the proven safety and efficacy of HPV vaccine, there remain several issues that impede its routine use, especially in low and middle-income countries These include public understanding that vaccination of a healthy person reduces the risk of that person contracting the disease, ease of access to vaccination, previous immunization experience, and parental concern over the sexual implications of HPV vaccination. Recently, the national health service of Taiwan announced that HPV vaccinations will be mandatory for girls entering junior high school across the country in 2019. We will provide an overview of the establishment and implementation of current HPV vaccination programs.

WENG Hao-Jui 103 (MANDARIN) (LEVEL 1) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: URTICARIA AND PRURITUS (LECTURES IN MANDARIN) THE PATHOGENESIS OF PRURITUS Pruritus is a prevalent symptom in dermatological disorders. It has been defined as an "unpleasant sensation that elicits the desire or reflex to scratch" by Samuel Hafenreffer, a German physician. It is an inevitable symptom to many disorders, including dermatological, neurological, psychogenic, systematic, and psychiatric diseases. Herein we will give a brief update on the recent discovery as well as crucial developments on the pathogenesis of pruritus.

WONG Sky Tin-Hau 102 (LEVEL 1) Saturday, May 11, 2019 - from 11:00 to 13:00 Session: STIMULATING INJECTABLES: WHAT'S NEW? A NEW DEVELOPMENT OF INJECTABLE POLYLATIC ACID (PLA) AND CLINICAL EXPERIENCE SHARING PLA is a useful biostimulator or great potential. The functionality of this material highly depends on the microstructure of the manufactured architecture. This can revolutionize the effect and indication. This presentation summarizes the new generation PLA in terms of the architectural advancement, benefit, functional and preliminary clinical outcome of the product.

WONG Sky Tin-Hau 201EF (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: UPDATES IN VASCULAR TREATMENT VARICOSE VEIN MANAGEMENT: MINIMALLY INVASIVE TREATMENTS VS SURGERY Varicose vein is a common pathological condition of general population. It is estimated around 10-25% of our population has various degree of varicose veins. The severity is stratified into different degree. Thanks to the advance in health consciousness of the public and screening procedures, more and more patients detect the condition at early stage, making minimally invasive treatments (MIT) possible and easy to perform. It is mainly divided into cutaneous treatment and intra-vascular treatment. This presentation dissects different aspects of the MIT.

WU Yu-Hung 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 08:30 to 10:30 Session: UPDATES IN DERMATOPATHOLOGY (LECTURES IN MANDARIN) MANY FACES OF CUTANEOUS LUPUS ERYTHEMATOSUS There are many cutaneous manifestation of lupus erythematosus (LE). In 1982, the American College of Rheumatology (ACR) proposed the diagnostic criteria for systemic lupus erythematosus (SLE) and revised in 1997. The ACR criteria was well-accepted and used for many years in the diagnosis of SLE. However, there are other skin diseases which may fit the ACR criteria (4 or more of 11 criteria) but are not SLE. Some patients with distinct skin and pathological presentations, such as bullous LE, subacute cutaneous LE, tumid LE, chilblain LE, lupus panniculitis, are not included in the ACR criteria. Therefore, a new Systemic Lupus International Collaborating Clinics Classification Criteria (SLICC) was proposed in 2012. In the new criteria, many variants of cutaneous LE were included in the definition of acute/subacute/chronic LE. Although many of these cutaneous LEs may not progress into SLE, they are still important and required correct diagnosis and appropriate management. The diagnosis of cutaneous LE predominantly relies on histopathology and immunofluorescence. Many patients of cutaneous LE have negative blood tests and is very different from SLE. In this lecture, we will introduce many different clinical presentations, various histopathological findings, and the importance of immunofluorescence in cutaneous LE. YANG Ching-Sheng PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 12:00 to 13:00 Session: SHOWCASE OF INJECTABLES: MIDFACE & NOSE THE DIFFICULT-TO-CORRECT DEPRESSIONS IN MID-FACE: MECHANISM AND MANAGEMENT Facial contouring by noninvasive method is always the hot topic in our clinical practice. With the knowledge of facial anatomy rising, we realized more about physiologic aging process, for example, the fat compartment aging change. Now, physicians can restore the face more effectively and naturally. However, there are still some problem cannot be solved perfectly. Especially the depressed area over mid and lower face junction. Some complication might arise if we overfill these depressed areas. There are not so much article discussing describing and explain the mechanism behind there depressed areas. Basing on the experience from facial lift, thread life and cadaver dissection, we try to form the hypothesis of mechanism in these difficult treat areas. Dividing the lateral face into anterior middle and posterior part by lateral canthus and anterior border of masseter muscle, the mechanism behind each of them is so different. Most of these areas come from structural problem which cannot be easily solved by filling material. The anterior one might associate with the ligament. The middle depression is due to fat dropping and herniation. The posterior depression come mainly from the location of parotid glands. We also reviewed the MRI images of 63 patients with at least 4 years interval apart, try to prove our hypothesis. There scientific data might help us know better about the facial aging change and avoid complication in our clinical practice.

YANG Jason Chih-Hsun 103 (MANDARIN) (LEVEL 1) Saturday, May 11, 2019 - from 16:30 to 18:00 Session: PRACTICAL DERMATOSCOPY (LECTURES IN MANDARIN) DERMATOSCOPIC PEARLS FOR THE PRIVATE-PRACTICE DERMATOLOGISTS By providing polarized magnification, dermoscopy improves the diagnostic accuracy in the clinical evaluation of pigmented skin lesions, but it is also enhance visualization of of vascular structures of nonpigmented skin disorders, including tumors but also inflammatory and infectious diseases. Similar to the impact of the otoscope, ophthalmoscope and stethoscope in improving the bedside diagnosis of ear, eye and heart conditions, the dermatoscope is anticipated to become an essential bedside tool for all the private-practice dermatologists.

YANG Chin-Yi 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS UPDATE ON SYSTEMIC THERAPIES FOR MANAGING MODERATE TO SEVERE ATOPIC DERMATITIS Patients with atopic dermatitis (AD) who do not adequately respond to topical therapy and phototherapy often need systemic immunomodulatory treatment to control their symptoms. Conventional systemic agents, such as cyclosporin, azathioprine, and methotrexate, have been used for decades, but there are concerns about their safety profile in long term use. The introduction of dupilumab in 2017 marked a major advance in systemic therapy for AD. Several other biologic agents and "small molecules" with varying mechanisms of action are in phase 2 or 3 development. Due to heterogeneous clinical phenotype of AD ,further work is required before the promise of a therapeutic revolution becomes reality.

YONEI Yoshikazu 101A (LEVEL 1) Saturday, May 11, 2019 - from 14:00 to 16:00 Session: CUTTING EDGE IN ANTI-AGING: STRESS, LED, HEALTHY AGING LET'S REDUCE GLYCATIVE STRESS, A RISK FACTOR FOR SKIN AGING Background: Glycation occurs when aldehydes, derived from reducing sugar (i.e., glucose, fructose) and alcohol, combines with a protein in a non-enzymatic reaction producing glycated proteins, finally forming body wastes called "advanced glycation end products (AGEs)". Furthermore, AGEs, not only deposited in the tissue, may also bind to a specific receptor called "RAGE (receptor for AGEs), followed by stimulating cellular signal pathways, inducing inflammatory cytokine production and causing inflammatory damages in skin and other tissues. Glycative stress is a risk factor of skin aging, i.e., loss of elasticity, yellowish change. Furthermore, AGEs stimulate pigment cells, thus enhancing melanin production which may cause melanin spots. It is meaningful to reduce glycative stress in order to keep young and healthy skin. Method: Four steps reducing the glycative stress are as follows; a) Prevention of glucose spikes b) Prevention of AGE formation c) Breaking AGEs d) Reducing AGEs/RAGE signal Results: Transient spikes in blood glucose concentration, like post prandial hyperglycemia, is called "glucose spices" which induce the production of various types of aldehyde, where the exposed aldehyde group (-CHO) of open-linear form glucose reacts with a chain-reaction behavior. We call this phenomenon "aldehyde sparks". Eating habits that reduce glucose spikes are to eat slowly, chew food well, eat breakfast, choose foods that do not raise blood sugar rapidly (i.e. foods with a low glycemic index). Supplementation of dietary fiber or a-glucosidase inhibitors is also effective. We can prevent AGE formation by a variety of active compounds derived from food. AGE generation was inhibited by extracts from tea (Camellia sinensis), Japanese persimmon leaf (Diospyros kaki), banabá (Lagerstroemia speciosa), kuma bamboo (Sasa veitchii), Chinese blackberry (Rubus suavissimus), and mixed herb of Roman chamomile (Anthemis nobilis), hawthorn berry (Crataegus laevigata, syn. C. oxyacantha), dokudami (Houttuynia cordata), and grape leaf (Vitis vinifera). One of our clinical studies showed that the 3-month oral treatment of the mixed herb ameliorate the skin elasticity. AGE breaking compounds are also available. Our study revealed that melatonin and extracts of pomegranate, water chenut (Trapa bispinosa Roxb.), rosemary (Rosmarinus officinalis), noni (Morinda citrifolia), and kuromoji (Lindera umbellata) can cleave the a-diketone structure of AGEs. Melanin production is markedly elevated when pigment cells are stimulated by AGEs. This reaction can be ameliorated by iridoids derived from extracts of noni, olive leaf or Japanese cornel (Cornus officinalis). There still are limited information regarding to compounds which control AGEs/RAGE signal. In our experiment, TNFa production from RAW264.7 macrophage cells was significantly elevated 3 hours after adding AGEs (CML-HSA) to the medium. Pretreatment with extracts of water chestnut, banabá, Chinese blackberry and persimmon leaf inhibited the TNFa production by 14.6%-22.7%. Conclusion: Glycative stress can be reduced through an appropriate diet, lifestyle. Intake of anti-glycation materials, inhibiting AGE formation and/or breaking AGEs, also may be useful in order to keep our skin young and beautiful.

YU Peter Yu 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 16:00 Session: ATOPIC DERMATITIS HOLISTIC MANAGEMENT OF ATOPIC DERMATITIS: FIRSTHAND EXPERIENCE FROM A DERMATOLOGIST WITH ATOPIC DERMATITIS Management of atopic dermatitis requires multidisciplinary approach aside from medical intervention. As an atopic dermatitis patient himself, the speaker would like to share his down-to-earth firsthand experience of dealing with atopic dermatitis with emphasis on environmental influences, including but not limited to clothing, air pollution, emollients, cleansing, probiotics and perspiration.

YU Peter Yu 201ABC (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: PEDIATRIC DERMATOLOGY PEDIATRIC DERMATOLOGY IN BRIEF: FROM A TO Z Pediatric dermatology is an emerging subspecialty of dermatology. This lecture would provide a brief introduction to some rather common but easily overlooked pediatric dermatology diseases to dermatologist who would like to catch a glimpse of this interesting field.

ZABNENKOVA Olga PLENARY HALL (LEVEL 3) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: SHOWCASE OF INJECTABLES: LOWER FACE & NECK PRECISE JAWLINE FOR YOUNG AND MATURE PATIENTS The chin plays an important role of entire facial appearance and also is the main structure that create precise jawline One of the signs of proportional, balanced faces are high cheekbones and a slightly protruding chin. A small, poorly developed chin is usually caused by congenital defects of the structure of the lower jaw, at least - post-traumatic or postoperative consequences. Restoring volume can significantly change the appearance of a person. About the small chin and say in that case, if its size and form do not match the proportions of the forehead, nose and cheekbones. The shape of the chin depends on the position of the lateral angle of the lower jaw and is determined by the severity of the "chin triangle" - protrusion in front of the chin area. It is believed that the ideal height of the chin is equal to half the height of the lower 1/3 of the face. The jawline should be sharp but smoothly contoured. In older patients, there is thinning and atrophy of soft tissues, loss of bone tissue (in particular, between the lateral parts of the lower jaw and chin), may appear forward-jaw furrow. In this case, chin plastic is necessary to improve the configuration of the lower jaw and give the face a more youthful appearance.

ZABNENKOVA Olga 201EF (LEVEL 2) Sunday, May 12, 2019 - from 16:30 to 18:00 Session: SCAR FORUM KELOIDS, HYPERTROPHIC AND ATROPHIC SCARS. WHAT'S NEW IN TREATMENT TECHNOLOGIES Introduction Scars are an inevitable and natural part of the healing process for most dermal wounds - they are a normal consequence of the body's physiological healing response. Most scars do not produce poor cosmetic or functional results. The original scar tissue is gradually replaced during the end phase of healing resulting in a reduction in redness, elevation and firm consistency of the tissue to produce a flat, soft, pale scar that is level with the adjacent skin. If, however, the delicate balance is not achieved during the healing process, the resulting scar may display abnormalities. Such types of abnormal scars are hypertrophic, keloid and atrophic scars. Various options are available for the treatment of keloid and hypertrophic scars including: surgical revision, laser surgery, steroid therapy, pressure garments, silicone gel sheets. BoTN in scar treatment is a new approach, which efficiently helps to reduce scar growing Chemical peels, laser resurfacing are most prevalent methods of treatment. Anyway new technique such as RF, subsission, filler & collagen injections can dramatically improve skin resurfacing

Material 10 males & femals with keloids & hypertrophic scars 25 femals & males with postacne atrophic scars

Сonclusion BoTN is a new trend in keloid scars treatment. It efficiently helps to reduce growing and itching of keloids scars. Also can be used as a preventive methods for keloids formation RF technique is a new approach in postacne scars treatment. HA and collagen filler injections can be recommended for treatment deep atrophic scars Abstracts Industry Sponsored Symposia ABSTRACTS INDUSTRY SPONSORED SYMPOSIA

ARKESTEIJN Walter NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 13:00 to 14:00 Session: MYGUARD - LUNCH SYMPOSIUM FACIAL APPEARANCE: CAPTURING THE REJUVENATION EFFECTS OF TREATMENTS IN BEFORE-AND-AFTER PICTURES WITH THE OBSERV® Human skin, and in particular the facial skin, has a strong aesthetic and social relevance. Making the facial skin appear beautiful has always been the primary goal in cosmetology and aesthetic medicine. The perception of beauty is strongly driven by human instinct; therefore, humans have underdeveloped the analytical ability to interpret and understand how different facial features contribute to the overall appearance of a person. Apparent physical facial attributes such as wrinkles, pigmentation spots and sagging skin are often easily identified, but features that are perceived subconsciously and which are more delicate and subtle are difficult to pinpoint and therefore remain unnoticed. However, it is exactly these delicate and hardly noticeable facial appearance features that are extremely valuable for the instinctual perception of beauty and are therefore key areas of interest for cosmetic interventions, both in cosmetology and in the aesthetic medicine industry.

Visualising these delicate features of the skin is challenging. Current conventional clinical imaging systems lack the sensitivity to adequately capture what the well-developed human perception process picks up instinctively. Subtle cosmetic treatment benefits are therefore hardly detectable on photos taken with conventional clinical photography systems. The OBSERV® sets itself apart from conventional clinical imaging systems as it is especially developed to capture exactly the delicate facial skin features that are relevant for the perception of beauty. The OBSERV® is equipped with a multimodal illumination system, which exposes the facial skin to a sequence of different light modes, and a camera system that observes the skin through various filters. As a result, different features and depths of the skin are alternately highlighted in such a way that they become more distinctly visible from other visual features of the skin. In turn, even the slightest and most subtle treatment benefits and appearance changes are revealed.

BERMAN Dror Dean NORTH LOUNGE (LEVEL 3) Sunday, May 12, 2019 - from 12:00 to 13:00 Session: WOH MEDICAL CROMA PHARMA : A FAMILY OWNED COMPANY THAT TREATS YOU AS FAMILY Founded in 1976, Croma-Pharma GmbH (Croma) is an Austrian family-owned company that specialises in the industrial production of hyaluronic acid syringes for the fields of medical aesthetics, ophthalmology and orthopaedics. Croma's Managing Director, Andreas Prinz explain" we are creating a strong global HA filler brand that stands for comprehensive quality, reliability and medical effectiveness."

CHUANG Celina Ying-Yen 201D (LEVEL 2) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: QUANTA SYSTEM TREATING ASIAN PIGMENTATIONS: MY RECIPE Treating complicated Asian pigmentary lesions is always a challenge. The pigmentary skin lesions in Asian is always a combination of superficial lentigo, macular seborrheic keratosis, melasma, or post-inflammatory hyperpigmentation. Thus, combining different wavelengths to target different types of pigmentary lesions located at different levels of the dermis is able to achieve normalized and rejuvenated skin in short number of sessions. GRAZIANO Antonio NORTH LOUNGE (LEVEL 3) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: RENAISSE AN INNOVATIVE REGENERATIVE TREATMENT : DERMIS MICRO-GRAFTING IN THE MANAGEMENT OF ANDROGENETIC ALOPECIA Background: Androgenetic alopecia (AGA) is a hereditary androgen-dependent, progressive thinning of scalp hair affecting 60-70% of the adult population worldwide. Pharmacological treatment offers moderate results and hair transplantation represents the only permanent treatment option, even if it requires a fairly invasive surgical procedure. The Rigenera® procedure is a clinical approach to obtain autologous micrografts ready to use and able to promote derma and bone regeneration, as already reported in previous studies. Aim: to demonstrate the efficacy and safety of micrografts obtained by Rigenera® procedure in the treatment of AGA performing a clinical and histological evaluation. To make this, one hundred patients were treated with autologous micrografts and clinically evaluated after 4, 6 and 12 months from treatment. Scalp dermoscopy and histological analysis were performed to assess the hair growth and histological appearance of the scalp. Results: Hair growth and density were improved at all indicated times showing an increase of total hair count and density with an increase and reduction of anagen and telogen phase, respectively. Scalp dermoscopic analysis also showed an improvement of hair density and histological analysis showed a clear amelioration of the scalp, development of new hair follicles and a beginning of cuticle formation. Conclusion: Autologous micrografts improve the hair growth and density suggesting their use in the AGA treatment.

HO Wilson 201D (LEVEL 2) Saturday, May 11, 2019 - from 10:00 to 13:00 Session: MERZ FULL FACE CONSIDERATIONS FOR INCOBOTULINUMTOXIN-A INJECTION Bont-A injection has been performed for decades, and injection techniques has been refined continuously as anatomical knowledge increases. On the other hand, incobotulinumtoxin-A is a botulinum toxi which is free of complexing protein, with proven efficacy and safety profile while minimising the risk of neutralising antibodies to core toxin formation. In this session, the speaker will share his vast experience in assessing individual facial contractions, and how we would do a treatment plan for his cases using incobotulinumtoxin-A.

HSU Che-Hao NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 13:00 to 14:00 Session: MYGUARD - LUNCH SYMPOSIUM THE USE OF OBSERV® TO EVALUATE MELASMA Melasma is a common, acquired, symmetric hypermelanosis characterized by irregular light to dark brown macules and patches among patients with darker skin types. Several clinical patterns of melasma have been described and melasma can also be further classified based on a Wood lamp examination to help identify the location of the pigment. Besides, increased vascularization in melasma lesions participates in the hyperpigmentation observed clinically. Melasma is a complex disorder having the hallmarks of a photoaging skin disease. Given the difficulty of appreciating disease in those with more subtle findings, we use the OBSERV® to evaluate melasma .

HUANG Hui-Peng 102 (LEVEL 1) Sunday, May 12, 2019 - from 09:30 to 11:00 Session: GALDERMA THE ROLE OF THE DERMATOLOGIST IN OCULAR DEMODICOSIS: A CLINICAL CHALLENGE Demodex spp. are common ectoparasites of the human facial skin. In the eye, D. folliculorum is found in the lash follicle, whereas D. brevis burrows deep into the lash's sebaceous gland and the meibomian gland. Cylindrical dandruff is pathognomonic of ocular D. folliculorum infestation. D. brevis has been linked to meibomian gland dysfunction, hordeolum and chalazion. Ocular demodicosis is really a clinical challenge to a dermatologist. Here we present 18 patients with ocular demodicosis. The clinical presentation, treatment and outcome will be discussed.

HWANG Chian-Yaw 201D (LEVEL 2) Sunday, May 12, 2019 - from 12:30 to 13:00 Session: COLLAMATRIX CLINICAL EXPERIENCE WITH PICOSECOND 595 NM LASER AND HEXA FRACTIONAL HANDPIECE Picosecond lasers have already been applied in the field of dermatology and cosmetic medicine for years. Its application was focusing on tattoo removal, managing pigmentary disorders, and treating scars. The mostly used wavelength for these indications are 755nm, 532nm, and 1064nm.

Lasers with 595nm wavelength is not unfamiliar to dermatologists. Dye laser with 595nm wavelength has been used to treat vascular lesions including flushing and rosacea. Q-switched 595nm Nd:YAG laser also has similar effect. 595nm picosecond laser also shows promising results when being used to treat vascular lesions.

Fractional lens array (HEXA handpiece) can create focal high fluence region separated by low fluence background. Once exceeds the threshold of laser-induced optical breakdown (LIOB), it will cause intra-epidermal vacuole formation, which leads to dermal remodeling. A carefully selected parameter can provide satisfactory result with short down time.

KING Walter 201D (LEVEL 2) Sunday, May 12, 2019 - from 10:00 to 10:30 Session: SOLTA THE LATEST ADVANCEMENTS: EXPERT'S EXPERIENCE FOR NON-INVASIVE TIGHTENING DEVICE -THERMAGE FLX We have used monopolar radiofrequency (Thermage) for skin tightening since 2003 starting with the first generation machine (Thermage Cool TC).

The 4th generation machine Thermage FLX was launched in Hong Kong in November 2017. The new machine is 25% faster with new treatment tip (Total Tip 4.0) which covers 35% larger surface area. New technology (ACCUREP) offers real time tuning with each pulse to account for variations in total impedance in order to deliver constant energy from one treatment site to the next. There are also improved patient and user experience for more comfortable treatment on the face and body plus ergonomically designed lighter handpiece to lower user fatigue. e.g. The 16cm2 body tip now has vibration for distraction to reduce discomfort..

Between December 2017 and April 2018, we have used the new 4th generation Thermage to treat 65 patients over the eyelids (29 patients), the face (55 patients), the whole neck (19 patients) and the abdomen (4 patients). Their age ranges from 29 to 77 and the mean age is 49. The male to female ratio is 1:5.5. The mean treatment duration for the eyelid tip (0.25cm², 450 shots) is 27 minutes, the face tip (4.0cm², 600 shots) is 38 minutes, the face and neck tip (4.0cm² 900 shots) is 50 minutes and for the body tip (16cm², 500 shots) is 85 minutes.

In our early experience with Thermage FLX, the new machine is faster with good doctor and patient satisfaction. There was no complication recorded.

LAM Phoebe Kar Wai 201D (LEVEL 2) Saturday, May 11, 2019 - from 15:00 to 16:00 Session: CLOVERS MEDTECH THE INSIDE ART OF SILHOUETTE INSTALIFT Absorbable suspension sutures (Silhouette Instalift) are composed of poly-L-acid/ poly lactide-co-glycolide (PLA/PLGA) bidirectional cones, which involves one entry and two exit points. When properly performed in the correct anatomical plane, not only the risks of infrequent complications (e.g. dimpling, edema), discomfort and downtime associated with this treatment are minimized. Excellent repositioning of descended tissue along the line of vector direction with secondary tissue regeneration and volumisation can be achieved with these suspension devices. Dependent upon the amount of facial ptosis and laxity, targeted treatment area, multiple sutures placement maximize treatment outcome and patient satisfaction. Tissue lifting and repositioning effect can be observed immediately following insertion of suspension devices, but results generally peaked after 5-6 months and maintained for 18 months to 24 months. Patient selection, the fine balancing of the patients' need and expectations are crucial in attaining optimal results. Other treatments e.g. Botox, dermal fillers and energy devices can be combined with suspension devices for a comprehensive total facial rejuvenation.

LI Chien-Nien 201D (LEVEL 2) Sunday, May 12, 2019 - from 13:00 to 13:30 Session: COLLAMATRIX- LUNCH SYMPOSIUM ALTERNATIVE APPLICATIONS IN PICOSECOND-LASER SCAR TREATMENT: MINI SPOT-SIZED MLA AND STACKING TECHNIQUE Picosecond laser with MLA (Micro-lens-array) has generally been used in the field of facial rejuvenation and scar treatment. In the first part of this session, the speaker will introduce the Mini-spot sized MLA handpiece (Mini-Hexa handpiece) of Picocare system and discuss about the suitable indications for Mini-spot sized MLA. Stacking technique, proposed by some physicians, indicates multiple continuous shots of fractional picosecond laser in the same treating area. Some physicians believe that this method performs better in the treatment of acne scar. The speaker will share some histologic pictures after stacking techniques (after MLA) and discuss about the possible mechanisms of neocollagenesis.

LIANG Ben Chung-Pin NORTH LOUNGE (LEVEL 3) Sunday, May 12, 2019 - from 12:00 to 13:00 Session: WOH MEDICAL HOW TO TREAT UPPER AND LOWER "SUNKEN EYES" WITH PRINCESS FILLER Periorbital rejuvenation is always a tough question. Superficial injection of subdermal filler for tear trough and sunken upper eyelid might easily result in an unpleasant outcome, such as blue hues due to Tyndall effect and irregularity. I suggest deep layer injection with "middle to low" molecular weight hyaluronic acid filler, ex. Princess filler, for correcting periorbital sunken eyes. For tear trough, periosteum and retaining ligament aim to refill. Upper sunken eyes and upper retro-orbital septum fat are the targets to treat.

LIU Li-Lin NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 13:00 to 14:00 Session: MYGUARD - LUNCH SYMPOSIUM CLINICAL APPLICATION OF OBSERV® TO REVEAL SUBTLE FACIAL TREATMENT EFFECTS Many skin conditions that surface in time, originate from the deeper skin layers and are difficult to diagnose with the naked eye. OBSERV® exposes those conditions by skin fluorescence and polarized light illumination technologies.

The benefits of a skin diagnosis with the OBSERV®: - Innovation in professional skin examinations - Full face visual contrast of skin fluorescences and pigmentation disorders - Clinical image system that reveals skin aging symptoms - Before and after photography to track treatment progress - iPad extensions for image capture and consultation

MARINI Leonardo NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 11:30 to 12:00 Session: SCIENTIS THE CLINICALLY PROVEN SUPERIOR BENEFITS / RISKS BALANCE OF CYSTEAMINE COMPARED TO KLIGMAN'S FORMULA Kligman formula remains to date the dermatologists' treatment of choice for melasma, yet side effects and draw-backs are significant: ochronosis, skin atrophy, irritation, photosensitivity and post inflammatory hyperpigmentation. Cysteamine is a natural molecule synthesized in human cells, and has a long history of safe use in human. Topical cysteamine was shown to have a significant depigmenting activity in 1960's and to be significantly more potent than hydroquinone in animal studies. Only recently, cysteamine was managed to be stabilized for use in topical products. It was shown to be significantly effective for the treatment of melasma in 2 double-blind, placebo-controlled randomized trials

Methods & Results: In a new study, the efficacy of Kligman's formula was compared with cysteamine in a group of 50 patients with epidermal melasma using MASI score and patients questionnaire. Four months of treatment with cysteamine or the Kligmans formula showed that the MASI scores were reduced in both groups. Cysteamine was more effective in reducing the MASI score at both evaluation points at 8 and 16 week, although the difference was not statistically significant. Cysteamine was significantly better tolerated than the Kligman's formula by patients. Sporadic cases are now being reported indicating that melasma patients who are resistant to Kligman's formula can show a significant therapeutic response to cysteamine.

Discussion: Cysteamine is at least as effective as the Kligman's formula. Cysteamine is a safe molecule with anti-mutagenic, anti-carcinogenic and anti-melanoma activities. The high efficacy of cysteamine as well as its high safety profile in contrast to Kligman's formula makes it a very promising alternative for the treatment of melasma.

MIYATA Nariaki 201D (LEVEL 2) Sunday, May 12, 2019 - from 13:30 to 14:00 Session: PICOWAY - LUNCH SYMPOSIUM DAWN OF A NEW ERA -NEW CONCEPT AND HANDPIECE OF TRIPLE WAVELENGTH PICOSECOND LASER FOR FULL FACE TREATMENT Picosecond laser became widely used in our field. It has proven better outcomes and minimal complications for pigmentation removal. Nowadays, many physicians use picosecond laser devices. However, in our daily practice, not only Q-switched lasers, but also long pulse lasers and IPL are very useful still now. Sometime, we cannot find the advantage of picosecond laser. Picosecond laser is newfangled. However, is it useful in reality? For Asians, picosecond laser need more evolution and expanded utilization. Patients require us to remove wrinkle, hair pore, scar, etc. with minimum down time. We need new concept for developing our procedures. Now is dawn of a new era. In technological aspect, I will show ideal wavelength, pulse duration, and innovative fractional handpiece of picosecond laser.

PENG Peter Hsien-Li NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 09:30 to 10:30 Session: CANDELA- TOTAL TREATMENT SOLUTION FOR SKIN REJUVENATION FRACTIONAL RF MIRCONEEDLING DEVICE FOR TREATING BODY SKIN LAXITY AND CELLULITE The skin is the biggest organ of the human body. The loss of elasticity and sagging is one of the main signs of aging, which can involve skins on any area of the body.

Many devices can provide beneficial effects on skin laxity through stimulation of the dermal collagen formation . The fractional microneeding RF can precisely target dermal tissue with the effect of new collagen, hyaluronic acid, and elastin fiber stimulation. This approach is designed to increase clinical efficacy and decrease possible side effects.

In this session, I will present the clinical experience and tips for better clinical results for body treatments with the fractional microneedling RF device.

PENG Peter Hsien-Li 201D (LEVEL 2) Sunday, May 12, 2019 - from 15:00 to 16:00 Session: LUMENIS LASER SKIN RESURFACING TREATMENT OUTCOME OF ACNE SCARS, SCARS, AND WRINKLES IN ASIANS WITH ULTRAPULSE CO2 LASER Acne is one of the most common-encountered diseases in dermatological practices all over the world. In non-Caucasian populations, scars and pigmentary sequelae can affect more than 50% of acne patients.

Fractional lasers first appeared about 15 years ago, and have since become the gold standard for acne scar treatment in non-Caucasian skin types. However, deeper atrophic acne scars - such as the ice pick or deep boxcar types, or scars with fibrotic bands in the deep dermis exceeding the approachable depth of many fractional lasers - require more penetrative approaches through precisely targeted fractional CO2 lasers.

Fractional CO2 lasers are also considered to be the gold standard for wrinkle reduction in Caucasian patients, though its use is limited in wrinkle treatments in Asians due to a higher incidence of Post-inflamatory hyperpigmentation (PIH). High powered fractional CO2 lasers are also reported to have positive effect on traumatic or burn scars.

In this session, I will present my clinical experiences in treating scars and wrinkles in Asian patients, and discuss steps to prevent side effects such as PIH.

SERRANO Gabriel NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 11:00 to 11:30 Session: SESDERMA THE NEW EDGE THERAPY IN THE MELASMA & SKIN REJUVENATION Microneedling is currently one of the best-known regenerative treatments, commonly used in dermatology and cosmetic surgery, not only to improve skin quality but as a coadjuvant therapy of melasma. Its mechanism of action is based on the stimulation of growth factors. Microneedling, changes the electric membrane potential and important amounts of growth factors are released by epidermic queratinocytes of the basal layer, such as: TGF-ß1, TGF-ß3, VEGF, EGF, IL-1, Follistatin (Fibroblast growth factor), TIMP2 (tissue inhibitor of metalloproteinases), TIMP 9, HGH, GM-CSF and so on. Microneedling restores the intercellular communication: the cellular cross-talk, balances the skin cytokine-ratio (inflammation vs non inflammation), increases the absortion of active ingredients and stimulates the synthesis of collagen fibres. It allows a broad range of indications, used alone or associated with other therapies such as chemical peels, lasers, dermal fillers, threads and PRP (platellet rich plasma).

TSENG Jonathan Te-Peng 201D (LEVEL 2) Sunday, May 12, 2019 - from 11:00 to 12:00 Session: UGINTECH IMPROVEMENT OF PERIORBITAL WRINKLES TREATMENT WITH 2 MM HIGH INTENSITY FOCUSED ULTRASOUND (ULTRAFORMER III) Microfocused ultrasound (MFU) is a unique technology to skin laxity. Over the past several years, the efficacy and safety of the device utilizing MFU have been well documented. By converting focused acoustic energy to heat, this device creates microcoagulative zones that induce inflammatory wound response. The most recent 2mm (5Mhz) high intensity focused ultrasound was introduced by ultraformer III delivers energy in an even safer and effective way for the treatment especially in periorbital region.

TSENG Jonathan Te-Peng NORTH LOUNGE (LEVEL 3) Sunday, May 12, 2019 - from 14:00 to 15:00 Session: RENAISSE REGENERATIVE TREATMENT OF ANDROGENETIC ALOPECIA WITH MICROGRAFTS: CLINICAL EXPERIENCE WITH TAIWANESE PATIENTS Androgenetic alopecia (AGA) is most commonly seen hair loss disorder. Although AGA is considered as relatively minor dermatological condition, however, cosmetic concerns lead certain amount of patients to seek treatment. The primary pharmacologic therapies for AGA are topical minoxidil and oral finasteride. Hair restoration surgery can also result in cosmetic improvement. Platelet-rich plasma severed as a regenerative modality has also shown some benefit. Recently, a new innovative regenerative treatment by using Micro-grafting technique from the occipital scalp in the management of AGA has proved its efficacy.

VIZINTIN Zdenko NORTH LOUNGE (LEVEL 3) Saturday, May 11, 2019 - from 14:00 to 15:00 Session: FOTONA: TREATMENT OF PIGMENTATIONS USING STARWALKER AND FRACTAT NEW APPROACH TO THE LASER TREATMENT OF PIGMENTATIONS AND TATTOOS Q-switched lasers are golden standard for removal of pigmentations and tattoos. Recently a novel technology for these applications was presented combining several modalities like are pico and nano second pulses, full spots and fractional micro spots. Combination of these modalities is enabling quicker and better clearance of tattoos and pigments with less adverse effects and with some additional beneficial features. This lecture will present this new technology and its first clinical results. Sponsors & Exhibitors Exhibitors

PLATINIUM SPONSORS

SILVER SPONSORS

A I Q AE+ Solution Incres Aesthetics Laboratory Co Quanta System SPA ACL Biomedical INNOAESTHETICS Allergan Institute Hyalual Switzerland R Ammon International Inc Renaisse Medicare Co Ltd Apyx Medical J Aromase Jeisys S ARTAS Robotic Hair Restoration System Jilin Folialux Bio-Tech Co Ltd Scientis APAC Pte. Ltd Jing Fung Sciton B Johnson & Johnson Sesderma Baush & Lomb Jtrue SNJ Co Ltd Beautycom Spirit Scientific Co Ltd Bionet RE. O. L STARNIC BP Biotechnology L'OrŽal Taiwan Sunmax Biotech Leader Book C Life Science T Candela Lumenis TBMS Clovers Medtech The Hydrafacial Company Collamatrix M Transverse Industries Co Ltd Medytox Taiwan D Menarini Taiwan U Denso Scientific Merz Aesthetics Ugintech Corporation Dermacare Meta Biomed Ultra V Deutarium Miradry Ushio Diamond Biotechnology Mona Frema DMK Para-Medical Skin Revision Myguard Co Ltd V Dynamic Medical Technologies Mylan Taiwan V8 Laser Vidivicy PTE Ltd F N Fotona Neoasia Taiwan W Woh Medical G O GAIA Genomics Opatra Ltd Y GAIE Yi Cheng Biotech Galderma Taiwan P Yungshin Pharma Phoenix Medical Taiwan Proprietary Limited H PINE BM Z Ho-Chi Medical Book Power Sapling Co Ltd Zero Gravity Skin PSET Biomed Corporation

9f, No. 102, Sec. 2, Roosevelt ALLERGAN Booth A49 Road Contact: Ms Jessy LIAO 10084 TAIPEI [email protected] Taiwan www.Allergan.com

A Bold, Global Pharmaceutical Company

Allergan plc (NYSE: AGN), headquartered in Dublin, Ireland, is a bold, global pharmaceutical company. Allergan is focused on developing, manufacturing and commercializing branded pharmaceutical, device, biologic, surgical and regenerative medicine products for patients around the world.

Allergan markets a portfolio of leading brands and best-in-class products for the central nervous system, eye care, medical aesthetics and dermatology, gastroenterology, women's health, urology and anti-infective therapeutic categories.

Allergan's Social Contract with Patients

Open Science

Allergan is an industry leader in Open Science, the Company's R&D model, which defines our approach to identifying and developing game-changing ideas and innovation for better patient care. This approach has led to Allergan building one of the broadest development pipelines in the pharmaceutical industry.

2f-2, No.12, Tien-mu West AMMON INTERNATIONAL INC Booth A21 Road Contact: Ms Ling Chen Shih-lin Dist., Phone: +886 228762691 Taipei Cell: +886 228762692 Taiwan [email protected] www.ipretty-amelia.com

Amelia Signature Collagen Hydrating Skincare Dermatologist-Recommended Formula ISO22716 CGMP Production Facility Highly effective Perfectly Gentle The best gift from nature- fish collagen peptide replenishes, rejuvenates, repairs, and restores your skin. With fish collagen peptide as the core ingredient of all Amelia skincare products, each product is dermatologist recommended and formulated WITHOUT silicones, dye, synthetic fragrances, mineral oils, or parabens. A collection that is as effective as it is safe, suiting all skin types, even sensitive skin

11f, No. 102, Sec.4 Civic BAUSCH & LOMB Booth C15 Boulevard Contact: Ms Selin CHEN 10690 TAIPEI Phone: +886 281619254 Taiwan Cell: +886 935618339 [email protected] www.bausch.com.tw/

Bausch + Lomb, a division of Bausch Health Companies Inc., (NYSE:BHC) (TSX:BHC), is solely dedicated to protecting and enhancing the gift of sight for millions of people around the world - from the moment of birth through every phase of life. Our mission is simple yet powerful: Helping you see better to live better.

The company is one of the best-known and most respected healthcare brands in the world, offering the widest and finest range of eye health products including contact lenses and lens care products, pharmaceuticals, intraocular lenses and other eye surgery products.

Our highest priority is the well-being of the people we serve. By listening to our customers and patients, by constantly honing our innovation edge, by executing with integrity and excellence, we strive to earn the trust of our partners and stakeholders.

Over the last 165 years, Bausch + Lomb has become a global hallmark for innovation and quality. Our talented and motivated colleagues work relentlessly to invent new materials, engineer new technologies, and ultimately bring new innovations to help people see better to live better.

We Market Three Broad Categories Of Products

Vision Care: Our contact lens offerings span the entire spectrum of wearing modalities and include such well-known brand names as ULTRA, Biotrue ONEday, PureVision, SofLens, Boston and Optima. Our lens care products include Biotrue and renu brand of chemical disinfectants for soft contact lenses as well as the Boston line of products for cleaning GP contact lenses.

Pharmaceuticals: Our products treat a wide range of eye conditions including glaucoma, eye allergies, conjunctivitis, dry eye and retinal diseases. We offer proprietary and generic medicines available by prescription, over-the-counter eye drops and other medications. Our line of proprietary Rx products includes the antibacterial eye drops Besivance, the steroid eye drops Lotemax, Alrex, and Zylet, and, Retisert and Vitrasert to treat retinal diseases. Outside the U.S., the non-selective beta blocker, Carteol; Minims, preservative-free, single-dose drops; and Liposic ointment for dry eye. Leading OTC products include the Ocuvite and PreserVision brands of ocular vitamins, Soothe dry eye drops, and Alaway allergy drops.

Cataract and Vitreoretinal Surgery: We offer a full suite of products including intraocular lenses and delivery systems featuring the Crystalens, SofPort and Akreos brands of IOLs, the Stellaris and Millennium lines of phacoemulsification equipment, and other surgical instruments and devices, including the Storz line of instruments.

No. 186, Section 2, Taiwan BEAUTYCOM Booth C20 Boulevard, Contact: Mr Jason ZHANG West District Phone: +886 423268080 40354 TAICHUNG [email protected] Taiwan www.beautynology.com

Beautycom technology Co., Ltd. was established in 1995, mainly introduce medical equipment and medical beauty supplies of well-known brands in European, Korea, and from other countries. Our products include Bistool Silicone facial implant from Korea, PUREFORM Gore-Tex facial implant from the United States, Korust UTIMS A1 ultrasound machine and PDO suture from European, all the medical equipment are approved by the Food and Drug Administration (TFDA) for medical equipment class IIregistration. In response of extend our market share of target market within the variety medical beauty market, we steadily increase our competitiveness and enforce to progress forward for accomplishing customer needs. Apparently, our customers are covering all he different major chain. Around 1000 Medical/beauty clinics in Taiwan are using our TFDA approved medical equipment, and our service quality standard does not be allowed to make any mistake in medical science technology. We indeed believe to satisfy Specialists' requirement is our main power of constantly momentum for moving forward.

Catic Plaza, Bda BEIJING JIAMEIDAOHE WELLNESS Booth C18 B-1402 MANAGEMENT CO., LTD Contact: Ms Ada LIU 100176 BEIJING Phone: +86 1067883887 China [email protected] www.dmk-cn.com

Beijing JiaMeiDaoHe Health Management Co., Ltd is the exclusive distributor of US imported brand, DMK, in the region of Mainland China, Taiwan, HongKong, and Maucau. DMK is the leading Para-Medical Skin Revision system which was created by the scientific visionary Danné Montague-King, DMK offers skin revision programs for all ages, skin conditions and ethnicities in more than 25 countries utilizing DMK products and treatments.

No.28, Ln. 36, Xinhu 1st Rd., BIONET RE.O. Booth A44 Neihu Dist., Taipei Contact: Ms Gwen LIN Taipei Phone: +886 0227951777#1574 Taiwan Cell: +886 0988390541 [email protected] www.reo.asia

BIONET Corp. was established in 1999 as the pioneer company in the field of stem cell applications in Taiwan. BIONET has focused in "Stem Cell Therapy", "Genetic Testing" and "Skin care". In 2017, RE.O open flagship store, located in Taipei's east district. RE.O continues to drive growth in distribution channels and seeks collaborations with beauty clinics and hospitals; in the meanwhile, expands its business through overseas sales channels.

5115 Ulmerton Road BOVIE MEDICAL CORPORATION Booth C14 33760 CLEARWATER Contact: Mrs Linda SCHOEMAN Florida [email protected] United States

ApyxTM Medical, the innovative rising star in the field of advanced energy, emerges from the renowned leader in medical device manufacturing, Bovie® Medical. Apyx Medical is poised to be a solution focused company in the cosmetic surgery market and the broader medical technology sector and endeavors to provide unique and creative solutions for the ever-changing needs of its physician customers and their patients.

No.57, Xing'ai Rd. BP BIOTECHNOLOGY Booth A19 11494 TAIPEI Contact: Ms Nancy KUO Taiwan Phone: +886 227939255 [email protected] www.bpbiotech.com.tw

BP Biotechnology was established in 2014 by a group of experts with over 10 years experience for developing sales strategies and marketing plans in Aesthetic industry. In order to stands at forefront in the industry, BP is keen to seize opportunities for business cooperation and to create an uncontested market strategies. It is the mission of BP Biotechnology dedicates to providing exceptional quality, value and service to our clients and customers.

17f-5, No.75, Sec. 1, Xintai 5th CLOVERS MEDTECH Booth C11 Road Contact: Ms Shinee Chang Xizhi Dist Phone: +886 2-86981098 221 NEW TAIPEI Cell: +886 913251896 Taiwan [email protected]

Clovers Medical Technology (Hong Kong) Ltd. was founded in 2015, mainly engaged in high-end medical aesthetic and medical products sales, now we are Greater China exclusive distributor of SILHOUETTE and ELLANSÉ®; from 2018, there are more brands will join our product line, especially biodegradable materials.

Our management team has more than 20 years of experience, strict selection of excellent products, is committed to market expansion and customer service, determined to become all pharmaceutical and medical equipment manufacturers' best strategic partner in the Greater China region.We uphold the integrity, quality, quality service and innovative spirit, to pursuit sustainable business growth; to internal, we care every employee's talent and provide a good working environment, learning opportunities and develop people to their full abilities. Company and employees with the development and success, to win-win situation.

26f, No.105, Sec. 2, Dunhua S. COLLAMATRIX Booth C23 Rd., Da-an Dist., Contact: Ms Lia CHUNG 106 TAIPEI CITY Phone: +886 2-2796-8096 Taiwan Fax: +886 2-2796-8028 [email protected] www.collamatrix.net

Collamatrix's R&D team is committed to developing biomedical materials (e.g., collagen, hyaluronic acid, bioceramics, and synthetic polymers) and applying them to various medical domains such as soft/hard tissue repair and filling. Collamatrix has received multiple awards for R&D achievements by the Department of Industrial Technology and the Ministry of Economic Affairs.

Collamatrix manufactures high-end biomedical materials and products by its own production technologies as well as internationally certified facilities and processes. Its standard production plants have been certified by ISO 13485 and GMP in Taiwan. The brands and products developed by Collamatrix that are already under mass production include CollaWound wound care products, CollaDental dental care products, and DermaFiller subcutaneous implants. Collamatrix's own series of products have been approved for sales successively.

No 232, Sec 3 Bade Road DENSO SCIENTIFIC Booth A42 10 Fl Contact: Ms Yongxu QIU 105 TAIPEI Phone: +886 02-25785932 Taiwan [email protected] www.denso-scientific.com

No. 88-5, Minquan Road DERMACARE Booth C1 Xindian District Contact: Mr Eric LI 23141 NEW TAIPEI Phone: +886 2-22186331 Taiwan [email protected] www.dermacare.com.tw

Rue De Bruxelles 10a DEUTARIUM Booth A33 B-1470 GENAPPE Contact: Pr Jacques DUBOIS Belgium Phone: +32 0478465369 [email protected]

Deutarium Belgium is a company that specialises in the creation and production of top-of-the-line products for dermatological and cosmetic use.

Rejuvenating Products

Clarifying and Depigmenting Products

Detoxifying and Hydrating Products

Founded in 2006 , Cosmetic Consultancy (R&D), Product development - own brand since 2015, Target : SPA, Dermatologists, Luxury Beauty shops

Production 100% Europe, Wallonia Belgium.

We draw inspiration from nature, from its beauty and its balance.

Our line of products may be used on all types of skin, from adolescence to old age, on both light and dark skin tones.

No. 145, 11 Fl, South Fuxing DIAMOND BIOTECHNOLOGY Booth A51 Road, Sec 2 Contact: Ms Yijun PAN 106 TAIPEI Phone: +886 227553320 Taiwan [email protected] www.diamond-biotechnology.tw/

No. 872, Jhongheng Rd DYNAMIC MEDICAL TECHNOLOGIES Booth C19 4f-1 Contact: Mrs Jessie Chiu New Taipei City Phone: +886 222217733 23586 JHONGHE CITY [email protected] Taiwan www.dmttw.com.tw/

Dynamic Medical Technologies Inc. (DMT) the market leader in the sale, maintenance and integrated marketing of aesthetic lasers and light-based equipment in Taiwan, was established in 2003. Headquartered in Taipei, DMT has four branch offices in Taiwan and three subsidiaries in Hong Kong, Guangzhou, and Beijing. DMT has been helping customers capitalize on the growing opportunities in the aesthetic laser sector by introducing novel equipment, providing excellent maintenance and marketing support. The marketing and service team of DMT is three times larger than its closest competitors. With their talent and dedication to offering the best, they have earned a distinguished reputation from both suppliers and customers. To have sustainable development with every customer, DMT makes an all-out effort to support customers in terms of customized marketing, aesthetician training and clinical operation consultation. We place great value in customer relationships and spare no expense to ensure...

Stegne 7 FOTONA Booth C6 1000 LJUBLJANA Contact: Ms Teja Mejak ARBI Slovenia Phone: +386 15009100 [email protected] www.fotona.com

Fotona is a world-leading medical laser company recognized for its innovative, award-winning laser systems for applications in aesthetics & dermatology, dentistry, surgery and gynecology. Fotona's global distribution network spans across more than 60 countries, ensuring comprehensive support and service for Fotona laser users, including clinical training, workshops and practical hands-on demonstrations. By establishing the Laser and Health Academy, Fotona has partnered with world-leading clinical experts to provide medical practitioners with a platform for continuing their professional growth. When you choose Fotona, you choose a company committed to designing, manufacturing and delivering: The highest performance, best made laser systems in the world.

-- GAIA Booth C33 Taipei Contact: Mr Vito HSU Taiwan [email protected]

813 No.226, Chongsin Rd GAIE Booth C9 Zuoying District Contact: Mr Huizhen LIU 80247 KAOHSIUNG Phone: +886 07-345-0040 Taiwan [email protected] www.gaie.com.tw

Managment Concept

To import high-quality and effective health care and cosmetic products and provide consumers with a "healthy, beautiful and active" life

Strategic Alliance

As a foundation for multi-channel, marketing, distribution, agent and private brand, with the major international suppliers to form a "network of international strategic alliances", the use of innovative marketing, information integration and collaboration strategies to meet customer needs .

G.A.I.E. Recommendation

The current focuses are on health care, cosmetic and biotechnology. More recently, we are join venturing with the top domestic biotech research groups to develop new products. The new product lines are to focus on human health.

Future Prospects

1. Strategic alliances with international partners in information sharing.

2. Turn the company-driven marketing to customers-driven marketing

3. Strengthen customer relationship, professional marketing plan designed for

4-6, 9f, No. 17 Sec. 1, Chengde GALDERMA TAIWAN Booth A9 Rd., Contact: Ms Nemea CHANG Datong Dist Phone: +886 2-2555-8850x202 103 TAIPEI CITY [email protected] Taiwan www.galderma.com

For over 35 years, Galderma has been partnering with healthcare professionals and academia across the globe to find new solutions to skin issues and deliver safe and efficient quality treatments to meet the skin health needs of people throughout their lifetime.

As the medical solutions business within Nestlé Skin Health, Galderma provides prescription drugs and aesthetic solutions, going beyond treating skin problems to also protect and enhance healthy skin, treat compromised skin and rejuvenate aging skin.

Today, dermatology is receiving a growing amount of recognition and attention. As we are living longer, caring for our skin as we age is also becoming increasingly important. Galderma is spearheading this change in the world's outlook on skin health.

As a focused dermatology company right from the start, Galderma is committed to the healthcare community, providing education and training programs as well as ongoing support to healthcare professionals throughout their career, to enable them to remain at the forefront of their field. To find out more about how Galderma engages with the dermatology community, click here.

Today, Galderma's extensive medical portfolio is available in 100 countries and treats a range of dermatological conditions including: acne, rosacea, nail mycosis, psoriasis & steroid-responsive dermatoses, pigmentary disorders, skin cancer and medical solutions for skin senescence (to find out more about Skin Conditions, click here).

Galderma medical brands include Epiduo, Differin, Mirvaso, Soolantra, Oracea, Loceryl, Metvix, Azzalure/Dysport, Restylane and Emervel (to view these brands, click here).

2277 Redondo Ave. HYDRAFACIAL MD® - EDGE SYSTEMS CORP. Booth C2 90755 SIGNAL HILL Contact: Joanna Ochoa California Phone: +1 5625970102 United States Fax: +1 5625970148 [email protected] www.edgeforlife.com

Edge Systems' premier device is the HydraFacial MD® skin solution based hydradermabrasion system, ranked one level above IPL. The HydraFacial MD® uses patented HydroPeel® tips to resurface the skin while introducing skin-enhancing solutions.

No. 147, Section 2, Jianguo INCRES AESTHETICS LABORATORY CO Booth C31 North Road, Contact: Ms Ching YANG Zhongshan District Phone: +886 225182351 10477 TAIPEI [email protected] Taiwan

500m East Of The Intersection JILIN FOLIALUX BIO-TECH CO LTD Booth C21 Of Contact: Ms Maggie LIU Xinggong Road And Haier Phone: +86 43189530967 Street Cell: +86 18626652504 Kuancheng District [email protected] 130000 CHANGCHUN www.folialux.com CITY,JILIN PROVINCE China

Changchun Foliaplast Bio-tech Co., Ltd(FOLIAPLAST) was established on March 28, 2015 and devoted to the research and development of biomedical materials and high-end medical devices. The company is base in Changchun and has four branch companies spread in the middle and south of China.

Jilin Folialux Bio-tech Co., Ltd. is a subsidiary of FOLIAPLAST, specializing in the design, synthesis, characterization, modification and processing of polymer materials and the production of their finished products to meet the needs of different customers. The polymer materials contain "The Fourth Generation Biomedical Materials": Poly(L-lactide), Poly(D-lactide), Poly(DL-lactide), Poly(?-caprolactone) and their copolymers such as PLGA, PDLGA, PLCL, PEG-PLLA, PEG-PDLLA, PEG-PLGA, PEG-PDLGA etc. With the good biocompatibility and biodegradability, our products are widely used for medical device applications such as absorbable sutures, orthopedic implants, cardiovascular devices, tissue regeneration, scaffolds as well as drug delivery, 3D printing, cosmetics etc.

The company pays attention to the introduction and cultivation of talents, and has established a high-quality, high-efficiency professional research team. The core team's professional background covers the fields of polymer synthesis chemistry, polymer processing, chemical engineering, and basic medicine. There are more than 60 formal employees, including 4 doctors and 6 masters. More than 80% of the staff own bachelor degree. The company has successfully developed a number of independent intellectual property products and established a reasonable research product line for the company's future development, and created good social benefits.

The company independently invested in the construction of Changchun ten thousand level laboratory, and also has the strategic partners: Raw Materials R&D Laboratory of Beijing Chemical Technology University, the Medical Material R&D Laboratory of Shanghai Donghua University, and Bioengineering Laboratory of Xi'an Jiaotong University.

We firmly believe that "quality is the basic guarantee for maintaining customer loyalty." The GMP and ISO13485 quality systems are the only standards we use to ensure the reliability and stability of our products. At present, our products have covered more than 20 countries from Asia, Europe, South America, North America and Africa.

We are committed to extending our regenerative medicine career from poly-l-lactic acid raw materials to medical devices, pharmaceuticals, plastic surgery, cosmetics and 3D printing, and give you our best service and products with our professionalism and enthusiasm.

1f., No.2, Aly. 2, Ln. 132, Leli JING FUNG Booth B24 3rd St Contact: Mr Kevin WANG Anle Dist Phone: +886 02-2432-2020 205 KEELUNG [email protected] Taiwan

-- JOHNSON & JOHNSON MEDICAL Booth B17 Taipei Contact: Ms Carol LIN Taiwan Phone: +886 27328345#765 Cell: +886 917238580 [email protected]

At Johnson & Johnson, we believe good health is the foundation of vibrant lives, thriving communities and forward progress. That's why for more than 130 years, we have aimed to keep people well at every age and every stage of life. Today, as the world's largest and most broadly based healthcare company, we are committed to using our reach and size for good. We strive to improve access and affordability, create healthier communities, and put a healthy mind, body and environment within reach of everyone, everywhere.

Every day, our more than 130,000 employees across the world are blending heart, science and ingenuity to profoundly change the trajectory of health for humanity.

4f., 319, Sec. 2, Tun Hwa S. Rd JOHNSON & JOHNSON TAIWAN LTD. Booth A11 106 TAIPEI Contact: Ms Cola LIAO Taiwan Phone: +886 2-27379803 Cell: +886 928517776 [email protected] www.jnj.com/

At Johnson & Johnson, we believe good health is the foundation of vibrant lives, thriving communities and forward progress. That's why for more than 130 years, we have aimed to keep people well at every age and every stage of life.

Today, as the world's largest and most broadly based healthcare company, we are committed to using our reach and size for good. We strive to improve access and affordability, create healthier communities, and put a healthy mind, body and environment within reach of everyone, everywhere.

10f.no.677, Mingcheng 3rd Rd., JTRUE Booth C40 Gushan Dist Contact: Ms Yajing CHEN 80453 KAOHSIUNG Phone: +886 75550408 Taiwan Fax: +886 75550409 Cell: +886 988318880 [email protected] www.jtruemed.com.tw

J-True Medical was founded in 2010, Our Head Office is located in Gushan District of Kaohsiung City, and branches in Taipei and Taichung . We focuses on actively developing and introducing new, valued products for facial plastic surgery. Obtaining the right to act as an agent for foreign medical equipment products and providing the latest training courses. The most important for us that aiming at product diversification and technological upgrading.

Over the years, J-True Medical has been deeply developing the field of professional sales and services of domestic medical equipments.

Current Product Line and Service: • Facial Plasty Surgery and reconstruction devices/ Exclusive Agent of Silhouette Sutures 360 Cone Sutures PureForm - Pre-shape 100% PTFE implants Nasal/Paranasal/Chin Surgiform100% ePTFE sheet implant Sun Medical sillicone implant Forehead/Temple/nasal/Paranasal/Chin • Training Courses provide 1. Rhinoplasty Workshop. 2. Silhouette Sutures Workshop. 3. Cooperating with Korean clinics to organize rhinoplasty courses and workshop.

第一支核准用於 中度至重度異位性皮膚炎 成人患者的生物製劑 22f, 7, Xinyi Road, Section 5 LOREAL-ACTIVE COSMETICS DIVISION Booth C3 Taipei 101 Tower Contact: Mr Kevin HSIEH 101 TAIPEI Phone: +886 2-81016000 ext5947 Taiwan Cell: +886 926842007 [email protected] WWW.LOREAL.COM.TW

CERAVE BEFORE CERAVE, a growing body of evidence had suggested that many dermatologic skin concerns are associated with a decreased level of ceramides in skin. During this time, MVE controlled release technology was exclusive to topical prescription products. IN 2005, CeraVe's dermatologists developed a line of skincare products CONTROL based on 3 essential ceramides and MVE Technology to help restore skin barrier function, and sustain long-term moisturisation with just one use. IN 2006, CeraVe was born with the launch of three core products: Moisturizing 眼見為憑 Cream, Moisturizing Lotion and Hydrating Cleanser TODAY, CeraVe offers over a range of products delivering therapeutic skincare for all and the continued promise of developing products with the expertise of dermatologists. PRODUCT OVERVIEW Ceramide loss is associated with numerous skin concerns, which is why CeraVe is positioned to address a variety of skin indications, including skin barrier disfunction, with a variety of gentle-yet-effective cleansers, creams, lotions, and facial moisturizers. 1. CLEANSERS CeraVe cleansers are free of soap, parabens, fragrance, and are allergy-tested and non-comedogenic. 2. FACIAL MOISTURISERS Barrier-building facial moisturizers go beyond recovery to protect and help optimize the look and feel of skin. 3. CREAMS & LOTIONS In formulas ranging from lightweight to nourishing, CeraVe supplies essential hydration with a comfortable texture suitable for every skin type. La Roche-Posay. Committed to dermatology. La Roche-Posay is committed to making dermatological skin care accessible to those who need it, by partnering with dermatologists from the development to the recommendation of our skin care products. We are committed to offering highly effective products that can be NOW AVAILABLE tolerated by even sensitive skin to improve the quality of life of anyone with skin concerns. A unique formulation charter Deep-rooted in dermatological heritage, La Roche-Posay skin care products are developed according to a strict formulation charter to combine safety and efficacy. • Proven effective ingredients, recognized by dermatologists • With soothing antioxidant thermal spring water • Ingredients strictly selected to be compliant with sensitive skin • Allergy-tested, non comedogenic skin care • Tested on sensitive skin • With packaging designed 有 效 且 持 續 改 善: to minimize possible contamination • Quality guaranteed by use-by date. We make sure that these criteria are met by strictly testing our products with some of the industry's most demanding protocols. Today, La Roche-Posay is •病灶面積和嚴重程度1,2 recommended by over 25,000 dermatologists worldwide and sold in over 50 countries. Our Commitment DISCOVER 1 LA ROCHE-POSAY'S 4 COMMITMENTS: • Recommended by over 25,000 Dermatologists worldwide. • Our •搔癢程度 Mission: A Better Life for Sensitive Skin. • La Roche-Posay Thermal Water from France. • Stringently formulated for safety. 長 期 耐 受 性 資 料: 333 Jilong Road LUMENIS Booth C17 1003 Contact: Ms Jennie LIU •52週時因不良事件引起的中止率低於安慰劑1 Bld 10 [email protected] 110 TAIPEI www.lumenis.com 使用前詳閱說明書警語及注意事項 Taiwan 【品名】杜避炎注射劑300毫克 (DUPIXENT solution for injection 300mg) 【包 裝】DUPIXENT (dupilumab)注射劑為澄清至淡乳白色、無色至淡黃色的溶液,其包裝為附有或不附有針頭防護套的單劑量預填注射器。 每支附有或不附有針 頭防護套的單劑量預填注射器內含DUPIXENT 300 mg的2 mL溶 液。DUPIXENT 的紙盒包裝內含2支附有針頭防護套的預填注射器或2支預填注射器。 【適應症】DUPIXENT可用於治療中度至重度異位性皮膚炎且對局部處方治療控制不 佳 或不 適 合 使 用該 療 法 的成 人 患者。DUPIXENT可併用或不併用局部皮質類固醇治療。 【劑量】DUPIXENT以皮下注射給藥。DUPIXENT於成人病患的建議劑量為一劑起始劑量600 毫克 (300 毫 克 注 射 兩 劑 ),接 著以 300 毫克隔週(every other week)注 射 一次。DUPIXENT可併用或不併用局部皮質類固醇治療。亦可使用局部鈣調神經磷酸酶抑制劑(topical calcineurin inhibitors),但應限用於臉部、頸部、腹股溝及會陰部等特殊患部。若漏打一次劑量,應指示病人在漏打劑量 後的7天內補行注射,之後則按照原有時程給藥。若漏打的劑量沒有在7天內注射,則病人應依照原有時程等到下次劑量再給藥。 【禁忌】DUPIXENT 禁用於已知對dupilumab 或其任何賦形劑過敏的病患[見仿單警語及注意事項]。 【警 語及注意事項】 1. 過敏反應: 臨床試驗中接受DUPIXENT治療之受試者的過敏反應發生率低於1%,這些過敏反應包括全身性蕁麻疹、血清疾病(serum sickness)或類血清疾病反應(serum sickness-like reaction)。出現血清疾病或類血清 疾病反應的2名受試者被認為與高效價之dupilumab抗體有關[見不良反應 (6.2)]。若出現臨床上重大過敏反應,DUPIXENT應停藥並給予適當治療[見仿單不良反應]。2. 結膜炎和角膜炎: 接受DUPIXENT治療的受試者有較高的結膜炎和角 膜炎發生率。結膜炎為最常被通報的眼睛疾患。大多數出現結膜炎的受試者其結膜炎在治療期間痊癒或逐漸康復[見仿單不良反應]。在為期16週 的 單 藥 治 療 試 驗 中,DUPIXENT治療組的角膜炎發生率<1% (每100受試者-年有1名)而安慰 劑組為0% (每100受試者-年有0名)。在一項 為 期 52週給予DUPIXENT+局部皮質類固醇(TCS)治療的試驗中,角膜炎發生率於DUPIXENT+ TCS治療組為4% (每100受試者-年有12名 ),安 慰 劑 + TCS治療組為0% (每100受試者-年有0名)。 Lumenis is a global leader in the field of minimally-invasive clinical solutions for the Surgical, Ophthalmology and 大多數出現角膜炎的受試者其角膜炎在治療期間痊癒或逐漸康復[見仿單不良反應]。請告知患者,當眼睛出現新的症狀或原有症狀惡化時,應告訴醫護人員。3. 同時患有氣喘: DUPIXENT用於治療氣喘的安全性和療效尚未建立。應告知 併有氣喘的患者,在尚未諮詢醫師前,不得擅自調整或停止氣喘治療。4. 寄生蟲 (蠕蟲) 感染: 在DUPIXENT的臨床試驗中排除已知有蠕蟲感染的患者,因此DUPIXENT是否會影響對抗蠕蟲感染的免疫反應尚不清楚。 【與其他藥物交互 Aesthetic markets, and is a world-renowned expert in developing and commercializing innovative energy-based 作用】 1. 活性疫苗: 接受DUPIXENT治療的患者應避免接種活菌疫苗。 2. 非活性疫苗: 有一項試驗為針對異位性皮膚炎受試者,在接受dupilumab 300 mg每週一次(為建議給藥頻率的2倍)共治療16週的情況下,給予疫苗接種並進行免 疫 反 應 評 估。受 試 者在 接 受 dupilumab治療12週後,接種減量破傷風白喉非細胞性百日咳混合疫苗 (Tdap) (AdacelR)及流行性腦脊髓膜炎疫苗(多醣體型) (Menomune R)。 4週後對破傷風類毒素及血清群C腦脊髓膜炎雙球菌多糖體進行 technologies, including Laser, Intense Pulsed Light (IPL) and Radio-Frequency (RF). 抗 體 反 應 評 估。Dupilumab治療組及安慰劑組受試者對破傷風疫苗及流行性腦脊髓膜炎疫苗(多醣體型)的抗體反應類似。至於對AdacelR及Menomune R疫苗之其他活性成分的免疫反應則未做過評估。) 3. 與細胞色素P450受質之交互作 用: Dupilumab對midazolam(經由CYP3A4代 謝 )、warfarin(經由CYP2C9代謝)、omeprazole(經由CYP2C19代 謝 )、metoprolol(經由CYP2D6代謝)及caffeine(經由CYP1A2代謝)藥動學所造成的影響,已在一項含12-13位異位性皮膚炎患者的試 驗中評估(皮下注射起始劑量600毫 克,接 續 每 周 300毫 克,共 六 周 )。AUC無臨床顯著改變。最大的影響是metoprolol(CYP2D6),增 加 29%的AUC。 【懷孕或授乳】懷孕:尚無DUPIXENT使用於懷孕婦女之相關數據,因此無法提供任何與藥 For years, Lumenis' ground-breaking products have redefined medical treatments and have set numerous 物相關之風險資料。授乳:當考量哺乳對嬰兒發育及健康的益處時,應同時考慮母親對DUPIXENT之 臨 床 需 求,以 及 DUPIXENT或母親的潛在病況對吸吮母乳的幼兒可能造成的任何不良影響。 【不良反應】 過敏反應、結膜炎和角膜炎、 注射部位反應、口腔皰疹、眼睛癢、其他單純皰疹病毒感染其他不常見之不良反應請詳閱藥品仿單。 【過量】DUPIXENT過量無特定的療法。當過量發生時,應監測病患是否出現任何不良反應的徵兆或症狀,並立刻給予適當的症狀性治 technological and clinical gold-standards. Lumenis has successfully created solutions for previously untreatable 療。 【藥理學特性】 Dupilumab是一種IgG4人 類 單 株 抗 體,它 能 專 一 性 地 結 合 於 介 白 素 -4 (IL-4)及介白素-13 (IL-13)受體複合體上的IL-4Rα次 單 位,進 而 抑 制 介 白 素 -4 (IL-4)及介白素-13 (IL-13)的 訊 息傳 遞。Dupilumab可藉由與第I類受體 conditions, as well as designed advanced technologies that have revolutionized existing treatment methods in each 結合而抑制IL-4訊息傳遞,以及藉由與第II類受體結合而同時抑制IL-4及IL 13之 訊 息傳 遞。Dupilumab阻斷介白素-4 α受體(IL-4Rα)可抑制IL-4 及IL-13細胞激素所誘發之反應,包括釋放促發炎細胞激素 (proinflammatory cytokines)、趨 化 素 (chemokines)及免疫球蛋白E (IgE)。ATC code: D11AH05 and every one of the sectors we operate in. 藥品許可證字號:衛部菌疫輸字第001082號 北市衛藥廣字第107100363 Our drive for innovation stems from an uncompromising commitment to improving the health and well-being of our 製 造 廠:Sanofi Winthrop Industrie (1051 Boulevard Industriel, 76580 Le Trait, France) Cook Pharmica LLC (1300 South Patterson Drive, Bloomington, IN 47403 USA) patients; addressing new and growing needs of aging populations; and in offering medical professionals cutting-edge 簡 易 仿 單 版 本日期:20180719 solutions that fit seamlessly into the health-economics environment of the 21st century. References: 1. DUPIXENT 產品仿單 2. Blauvelt A et al. Lancet.2017;389(10086):2287-2303.doi:10.1016/S0140-6736(17)31191-1.

賽諾菲股份有限公司 台北市11010松仁路3號7樓 電話: (02) 2176-5588

© 2018 Sanofi and Regeneron Pharmaceuticals, Inc. All Rights Reserved. SATW.DUP.18.11.0380 (11/18) 第一支核准用於中度至重度異位性皮膚炎 成人患者的生物製劑 CONTROL 眼見為憑

NOW AVAILABLE

有 效 且 持 續 改 善: •病灶面積和嚴重程度1,2 •搔癢程度1

長 期 耐 受 性 資 料: •52週時因不良事件引起的中止率低於安慰劑1

使用前詳閱說明書警語及注意事項 【品名】杜避炎注射劑300毫克 (DUPIXENT solution for injection 300mg) 【包 裝】DUPIXENT (dupilumab)注射劑為澄清至淡乳白色、無色至淡黃色的溶液,其包裝為附有或不附有針頭防護套的單劑量預填注射器。 每支附有或不附有針 頭防護套的單劑量預填注射器內含DUPIXENT 300 mg的2 mL溶 液。DUPIXENT 的紙盒包裝內含2支附有針頭防護套的預填注射器或2支預填注射器。 【適應症】DUPIXENT可用於治療中度至重度異位性皮膚炎且對局部處方治療控制不 佳 或不 適 合 使 用該 療 法 的成 人 患者。DUPIXENT可併用或不併用局部皮質類固醇治療。 【劑量】DUPIXENT以皮下注射給藥。DUPIXENT於成人病患的建議劑量為一劑起始劑量600 毫克 (300 毫 克 注 射 兩 劑 ),接 著以 300 毫克隔週(every other week)注 射 一次。DUPIXENT可併用或不併用局部皮質類固醇治療。亦可使用局部鈣調神經磷酸酶抑制劑(topical calcineurin inhibitors),但應限用於臉部、頸部、腹股溝及會陰部等特殊患部。若漏打一次劑量,應指示病人在漏打劑量 後的7天內補行注射,之後則按照原有時程給藥。若漏打的劑量沒有在7天內注射,則病人應依照原有時程等到下次劑量再給藥。 【禁忌】DUPIXENT 禁用於已知對dupilumab 或其任何賦形劑過敏的病患[見仿單警語及注意事項]。 【警 語及注意事項】 1. 過敏反應: 臨床試驗中接受DUPIXENT治療之受試者的過敏反應發生率低於1%,這些過敏反應包括全身性蕁麻疹、血清疾病(serum sickness)或類血清疾病反應(serum sickness-like reaction)。出現血清疾病或類血清 疾病反應的2名受試者被認為與高效價之dupilumab抗體有關[見不良反應 (6.2)]。若出現臨床上重大過敏反應,DUPIXENT應停藥並給予適當治療[見仿單不良反應]。2. 結膜炎和角膜炎: 接受DUPIXENT治療的受試者有較高的結膜炎和角 膜炎發生率。結膜炎為最常被通報的眼睛疾患。大多數出現結膜炎的受試者其結膜炎在治療期間痊癒或逐漸康復[見仿單不良反應]。在為期16週 的 單 藥 治 療 試 驗 中,DUPIXENT治療組的角膜炎發生率<1% (每100受試者-年有1名)而安慰 劑組為0% (每100受試者-年有0名)。在一項 為 期 52週給予DUPIXENT+局部皮質類固醇(TCS)治療的試驗中,角膜炎發生率於DUPIXENT+ TCS治療組為4% (每100受試者-年有12名 ),安 慰 劑 + TCS治療組為0% (每100受試者-年有0名)。 大多數出現角膜炎的受試者其角膜炎在治療期間痊癒或逐漸康復[見仿單不良反應]。請告知患者,當眼睛出現新的症狀或原有症狀惡化時,應告訴醫護人員。3. 同時患有氣喘: DUPIXENT用於治療氣喘的安全性和療效尚未建立。應告知 併有氣喘的患者,在尚未諮詢醫師前,不得擅自調整或停止氣喘治療。4. 寄生蟲 (蠕蟲) 感染: 在DUPIXENT的臨床試驗中排除已知有蠕蟲感染的患者,因此DUPIXENT是否會影響對抗蠕蟲感染的免疫反應尚不清楚。 【與其他藥物交互 作用】 1. 活性疫苗: 接受DUPIXENT治療的患者應避免接種活菌疫苗。 2. 非活性疫苗: 有一項試驗為針對異位性皮膚炎受試者,在接受dupilumab 300 mg每週一次(為建議給藥頻率的2倍)共治療16週的情況下,給予疫苗接種並進行免 疫 反 應 評 估。受 試 者在 接 受 dupilumab治療12週後,接種減量破傷風白喉非細胞性百日咳混合疫苗 (Tdap) (AdacelR)及流行性腦脊髓膜炎疫苗(多醣體型) (Menomune R)。 4週後對破傷風類毒素及血清群C腦脊髓膜炎雙球菌多糖體進行 抗 體 反 應 評 估。Dupilumab治療組及安慰劑組受試者對破傷風疫苗及流行性腦脊髓膜炎疫苗(多醣體型)的抗體反應類似。至於對AdacelR及Menomune R疫苗之其他活性成分的免疫反應則未做過評估。) 3. 與細胞色素P450受質之交互作 用: Dupilumab對midazolam(經由CYP3A4代 謝 )、warfarin(經由CYP2C9代謝)、omeprazole(經由CYP2C19代 謝 )、metoprolol(經由CYP2D6代謝)及caffeine(經由CYP1A2代謝)藥動學所造成的影響,已在一項含12-13位異位性皮膚炎患者的試 驗中評估(皮下注射起始劑量600毫 克,接 續 每 周 300毫 克,共 六 周 )。AUC無臨床顯著改變。最大的影響是metoprolol(CYP2D6),增 加 29%的AUC。 【懷孕或授乳】懷孕:尚無DUPIXENT使用於懷孕婦女之相關數據,因此無法提供任何與藥 物相關之風險資料。授乳:當考量哺乳對嬰兒發育及健康的益處時,應同時考慮母親對DUPIXENT之 臨 床 需 求,以 及 DUPIXENT或母親的潛在病況對吸吮母乳的幼兒可能造成的任何不良影響。 【不良反應】 過敏反應、結膜炎和角膜炎、 注射部位反應、口腔皰疹、眼睛癢、其他單純皰疹病毒感染其他不常見之不良反應請詳閱藥品仿單。 【過量】DUPIXENT過量無特定的療法。當過量發生時,應監測病患是否出現任何不良反應的徵兆或症狀,並立刻給予適當的症狀性治 療。 【藥理學特性】 Dupilumab是一種IgG4人 類 單 株 抗 體,它 能 專 一 性 地 結 合 於 介 白 素 -4 (IL-4)及介白素-13 (IL-13)受體複合體上的IL-4Rα次 單 位,進 而 抑 制 介 白 素 -4 (IL-4)及介白素-13 (IL-13)的 訊 息傳 遞。Dupilumab可藉由與第I類受體 結合而抑制IL-4訊息傳遞,以及藉由與第II類受體結合而同時抑制IL-4及IL 13之 訊 息傳 遞。Dupilumab阻斷介白素-4 α受體(IL-4Rα)可抑制IL-4 及IL-13細胞激素所誘發之反應,包括釋放促發炎細胞激素 (proinflammatory cytokines)、趨 化 素 (chemokines)及免疫球蛋白E (IgE)。ATC code: D11AH05

藥品許可證字號:衛部菌疫輸字第001082號 北市衛藥廣字第107100363 製 造 廠:Sanofi Winthrop Industrie (1051 Boulevard Industriel, 76580 Le Trait, France) Cook Pharmica LLC (1300 South Patterson Drive, Bloomington, IN 47403 USA) 簡 易 仿 單 版 本日期:20180719

References: 1. DUPIXENT 產品仿單 2. Blauvelt A et al. Lancet.2017;389(10086):2287-2303.doi:10.1016/S0140-6736(17)31191-1.

賽諾菲股份有限公司 台北市11010松仁路3號7樓 電話: (02) 2176-5588

© 2018 Sanofi and Regeneron Pharmaceuticals, Inc. All Rights Reserved. SATW.DUP.18.11.0380 (11/18) 12f-1, No. 293-1, Zhongshan MACROHI CO LTD Booth A15 Rd. Contact: Ms Ting-Yu CHEN Banqiao Dist., Phone: +886 2-8952-1800 ext229 22065 NEW TAIPEI Cell: +886 912888643 Taiwan [email protected] www.aromase.com.tw

Aromase's founder, Eric Chen was raised to believe that there is always a solution for any problem, especially when it comes to scalp and hair. This belief was put to the test when he noticed his father was suffering seborrheic-dermatitis caused by certain chemical ingredients, and he couldn't find anything in the market that could help him improve his condition. For this reason, Eric decided to start studying herbal ingredients and their effects, hoping he could help his father as well as all others who were being affected by chemicals. Growing up and throughout the course of his studies, he noticed a big gap in the hair care industry, scalp care. After joining in his great-grandfather's footstep, him being the third generation in his family dedicated to the hair care industry, he decided to utilize the 60 years' of know-how he inherited to conduct R&D in the hopes of producing a product that could improve any scalp conditions.

At Aromase, we offer a range of treatments that help improve the overall condition of your scalp with lasting results, giving you both healthy hair and a healthy scalp. At Aromase, we conduct the necessary research to find out what the market needs and what solution we can offer before we start developing our products, intending to not just offer a solution but a better quality of life as well.

872 Jhongjheng Rd MEDYTOX TAIWAN Booth C7 4f-1 Contact: Ms Tina LIN Taipei County Phone: +886 22217733 235 JHONGHE [email protected] Taiwan

Medytox, a global biopharmaceutical company, is at the forefront of efforts to build a better future with ceaseless R&D.

Since the launch of botulinum toxin type A Meditoxin® in 2006 (trade name: Neuronox®, Siax®, Botulift®, Cunox®, Acebloc® and Meditoxin®), Medytox has shown a dramatic growth. Medytox reached nearly 40% of market share in Korea since 2009 and is expected to increase even further with various indications being included. The global botulinum toxin market continues to grow and is expected to further expand to not only medical aesthetics market but also therapeutic market. Medytox is stunning the world with high market share in the global botulinum market. With the goal of penetrating to the US and Europe, we plan to exceed 10% of the market share in the global market along with the launch of the currently developing new type botulinum toxin products. In the future, Medytox will grow as the leader of the biopharmaceutical industry by challenging ourselves with passion for the global market.

17f., No.65, Sec.2, Dunhua S. MENARINI TAIWAN Booth A46 Rd Contact: Mr Ashton WANG DAAN DIST Phone: +886 2 2708 1863 #73 106 TAIPEI [email protected] Taiwan www.menariniapac.com

Menarini Asia-Pacific is part of the world's largest Italian biopharmaceutical company - Menarini Group which was founded 1886 and has over 16,000 employees in more than 100 countries. Menarini Asia-Pacific's vision is to be a leading provider of important healthcare brands to improve the lives of people in the region. Menarini Asia-Pacific operates across the entire commercial value chain, from clinical development, regulatory approval and product launch to lifecycle management with a diverse portfolio of proprietary and partnered brands in key therapeutic fields, including Consumer Health, Dermatology, Primary Care, Allergy/Respiratory, Cardiovascular, Oncology/Specialty Care and Men's Health.

270 Osong Soengmyeong 1-ro META BIOMED Booth C12 Osong-eup Heungdeok-gu Contact: Mr Jason LEE Cheongju-si Phone: +82 26933952 - CHUNGCHEONG BUK-DO Cell: +82 69337525 South Korea [email protected] www.meta-biomed.com

Since its foundation in 1990 as a manufacturer of medical devices to contribute to the development of health&medical industry, META-BIOMED CO., LTD., has manufactured excellent products such as not only biodegradable surgical sutures but also dental products through sustained R&D and are exporting such products to over 80 countries including the USA and Europe creativity and challenge.

445 Indio Way MIRAMAR LABS Booth A10 94085 SUNNYVALE Contact: Stella Zervos California Phone: +1 4089408700 United States Fax: +1 4089408795 Cell: +1 7274822124 [email protected] www.miradry.com

miraDry® The Sweat Stops Here.TM miraDry® is the only FDA cleared, non-invasive procedure for the immediate and lasting reduction of underarm sweat. miraDry permanently destroys sweat and odor glands while protecting the surrounding tissue. miraDry continues to deliver one of the highest patient satisfaction ratings of all aesthetic procedures.

Rm. B1, 13f., No.502, Jiuru 1st MONA FREMA Booth A22 Rd., Sanmin Dist., Contact: Ms Meizi YANG 807 KAOHSIUNG Phone: +886 073864799 Taiwan Fax: +886 073864808 Cell: +886 0926824248 [email protected] monafrema.com.tw

Derma-Xpert : Skin-care Guardian

Love.Hope.Proud

Infant Safety Standard, Zero Skin Burden Former leading cosmeceutical brand Mona Frem'a from Lovaty Bio-Tech Aesthetics Corporation established in 1999, Derma-Xpert is born regarding to providing Asian sensitive skin users to become a skin-care guardian brand.

Derma-Xpert continuously focus on high-end formula in a professional skin-caring perspective, offering high-effective dedicated skin-care products for all users.

Most state-of-the-art equipment and complies with the strictest ISO 22716 GMP certification, we adapt nearly 100% medical-used multi-layer deionized pure water to decrease preservative application and eliminates impurities of water to lower skin stimulus.

All products certified infant-application safety standard without any controversial ingredients and alcohol in formula.

We are widely promoted and recommended in most dermatological clinics, medical aesthetics centers and hospitals.

3f.-2, No.146, MYGUARD CO., LTD Booth A26 Wenxing Rd., Guishan Contact: Ms Kelly HSIEH 33377 TAOYUAN Phone: +886 3-3270080 Taiwan Cell: +886 972147227 [email protected] www.myguard.com

MYGUARD Co., Ltd. possesses over 20 years of professional experience and is committed to the development of novel cosmetic and beauty care technology over the long term. MYGUARD not only has a long-term partnership with global cosmetic brands and medical dermatology institutes, but acts as the agent and develops skin & hair diagnostic systems and optical instruments to evaluate the needs of the customers and provide professional services.

Compared to traditional diagnostic system, MYGUARD introduces innovative technology into aesthetic medicine and cosmetology by combining the application of mobile devices, so you could skip complicated steps and create an interactive relation with customers.

The three core values of MYGUARD:

INNOVATION: Compared to traditional models, MYGUARD is committed to the development of skin & hair diagnostic systems in the application of novel innovative technology.

MOBILE: By combining the mobile devices, customers can keep track of their health information and benefit from multivariate services and consultations in real-time.

BEAUTY: Create your exclusive skin health plans so that "The beauty of tomorrow is visible today"!

Minquan East Road, No. MYLAN TAIWAN Neihu District, Section 6, Contact: Ms Sky LIU 114 TAIPEI Phone: +886 266031688 Taiwan [email protected] www.mylan.com.tw

5f, No. 58, Singjhong Rd NEOASIA LTD. Booth A31 Neihu Dist. Contact: Ms.Peng-Yu-Li 11469 TAIPEI Phone: +886 2-87917778 #5102 Taiwan Cell: +886 988572563 [email protected] www.neoasia.com.tw

NeoAsia Ltd. is a leading company in medical aesthetics industry of Taiwan. Established in 1993, the company initially devoted itself to acting as a sales agent for cosmeceutical brands NeoStrata and NeoTec, as well as medical aesthetics equipment such as Alma and Deka laser. NeoAsia has also established a Biotech R&D Center and a cosmetics factory with GMP authentication. In recent years, the company has made a successful entry into the biomedical field and gained a reputation in this field.

447 High Road OPATRA LTD Booth A13 N12 0AF LONDON Contact: Mr Efraim SALHOV United Kingdom Cell: +44 07581293831 [email protected] www.opatra.com

At Opatra Advanced Skincare Technologies, we bring together the latest technological leaps and scientific innovations to create potent skincare solutions and dynamic tools that are redefining the beauty industry. As a leading device manufacturer and wholesaler, Opatra recognizes that our remarkable success is a reflection of your happiness with our easy-to-use instruments that help to produce healthy, youthful, and glowing skin. Our most recent breakthrough, DERMISONIC, is a revolutionary anti-aging and skin-repairing device that combines four scientifically-proven treatments—galvanic technology, ultrasound stimulation, LED light therapy, and vibrating massage. Together these treatments work to rejuvenate skin by smoothing out facial wrinkles, tightening facial muscles, boosting blood circulation, and stimulating new skin cell production with one powerful, hand-held machine.

6f, No.243, Sec 1, Fuxing South PHOENIX MEDICAL TAIWAN PROPRIETARY Booth B5 R., LIMITED Contact: Mr Jones Lai Da'an Dist., Phone: +886 2-27015157 10666 TAIPEI Fax: +886 2-27015057 Taiwan Cell: +886 932802619 [email protected]

Phoenix Medical Taiwan Pty Ltd (PMT) is a professional pharmaceutical and medical device distributor which is mainly focusing on skincare area in Taiwan market. PMT is dedicated to work with Dermatologists and Aesthetic surgeons to improve people's skincare management and quality of life. PMT covers entire Taiwan medical centers, Dermatology clinics, Aesthetic clinics, Pediatric clinics and chain pharmacies by full marketing, sales & logistics functions.

PMT is authorized by Good Pharma Dermatology, Singapore to distribute Suu Balm range including Suu Balm Cream, Suu Balm Kids Cream, Suu Balm Wash & Suu Balm Kids Wash in Taiwan market.

If you are interested in Taiwan market or our products, please kindly contact our founder, Mr. Jones Lai through this mail address, [email protected] or mobile number at +886 932 802 619. We are looking forward to providing you our best quality of service.

120-11 Techno 2-ro PINE BM Booth B7 Yuseong-gu Contact: Mr Frank LEE 34029 DAEJEON Phone: +82 427107308 South Korea Cell: +82 1049504589 [email protected] www.pinesutures.com

-- POWER SAPLING CO., LTD Booth A14 114 TAIPEI Contact: Ms Vicky CHEN Taiwan Phone: +886 287518876 Cell: +886 912858250 [email protected] www.skinc.com.tw

#2, Siwei Lane, Zhongzheng PSET BIOMED CORPORATION Booth C30 Road Contact: Ms Emily CHIANG 2-fl, #7 Phone: +886 222230558 231 NEW TAIPEI [email protected] Taiwan

Via Iv Novembre 116 QUANTA SYSTEM SA Booth A29 21058 SOLBIATE OLONA VA Contact: Mr. Paolo Salvadeo Italy Phone: +39 0331376797 Fax: +39 0331367815 [email protected] www.quantasystem.com

Quanta System is a worldwide leading manufacturer of single source and multi-wavelength lasers for Medical and Aesthetic applications. Advanced research and the unrivalled Mixed Technology rank Quanta System in the forefront of the Aesthetic market

2f, No.97 Sec 2 ,dunhua S Rd. RENAISSE MEDICARE CO LTD Booth C22 106 TAIPEI Contact: Mr Henry FAN Taiwan Phone: +886 277111080 Fax: +886 277117288 Cell: +886 955991266 [email protected] www.renaisse.com.tw

A Renaisse Group Renaisse Medicare's head office is in Taipei city. Our branch office is in Hong Kong, Shen Zhen and Shang Hai. We provide state of the art aesthetic medical solutions including of medical device, comeceuticals, aesthetic devices,... and so on. Unleashing the potential to achieve true beauty and healthy skin is the philosophy that drives Renaisse Medicare. Serving customers from the heart, we take the pride in its relentless pursuit of quality service and clinically-validated products. We keep learning from professionals all over the world and offer a plateform to assist physicians communicate and study with each other internationally. Since inception in 2003, Renaisse Medicare has become a leader in aesthetic medical field in Pan Asia Area.

128 Baytech Drive RESTORATION ROBOTICS, INC. Booth C25 California Contact: Ms Cecilia WONG 95134 SAN JOSE Phone: +1 4088836888 California Cell: +65 81685788 United States [email protected] www.restorationrobotics.com

925 Commercial St SCITON Booth A33 94303 PALO ALTO Contact: Mr. Thomas Beatrous California Phone: +1 6506952900 United States [email protected] www.sciton.com

Sciton is committed to providing best-in-class laser and light solutions for medical professionals who want superior durability, performance and value. Sciton offers high-quality medical devices for laser-assisted lipolysis, fractional and full-coverage skin resurfacing

CLINICAL FACIAL ANATOMY

DISSECTION & & LIVE INJECTION 28 29 AMSTERDAM THE NETHERLANDS COURSE JUNE

SESSION 2019

CFA Summer 2019 is COMPLIANT with the MedTech Europe Code of Ethical Business Practice. Event reference: EMT14562

O R G A N I Z E D I N C O O P E R A T I O N W I T H

Russian State Research Medical University (RSRMU) and the Department of Anatomy and Embryology, Leiden University Medical Center (LUMC) The CFA course is officially approved and endorsed by the Netherlands Society of Plastic Surgery, the Netherlands Society of Aesthetic Plastic Surgery and WWW.EUROMEDICOM.COM The British Association of Aesthetic Plastic Surgeons 7f, No.133, Sec 3, Minsheng E. SESDERMA Booth A27 Rd., Contact: Ms Katie CHEN Songshan District Phone: +886 2-24796794 ext65 Taipei Cell: +886 970568216 Taiwan [email protected] www.sesderma.com.tw/

Founded in 1989 by a team of dermatologists led by Dr. Serrano, Sesderma is a laboratory whose "raison d'être" is the health and well-being of people. This is attained through actively listening to the skin of our patients. Our commitment for innovation and treating skin conditions stems from a passion for solving health problems that originate, not only on the surface, but also in-depth. In this line, we apply NANOTECHNOLOGY for the development of solutions suited to every skin need. Active ingredients are transported in liposomes, extraordinarily small Nano-sized capsules that reach the core of the problem. The result: Highly efficient treatments with great tolerance.

We provide comprehensive treatments for every skin need because solving skin problems for everyone is in our DNA.

Our dermocosmetic products and treatments reach out both skin health and beauty. That is why we have developed two main lines: Sesderma, for the end customer and Mediderma, an exclusive brand aimed at professionals.

Room 408, Block 6, No. 3601 SHANGHAI ENAR BIOTECHNOLOGY CO., LTD Booth A59 Donfang Road Contact: Ms Zhu XUE Pudong Dist Phone: +86 2158889190 00000 SHANGHAI Cell: +86 18583750921 China [email protected]

No. 608, Ace Techno Tower 2, SNJ CO., LTD Booth C41 Digitalro, 31-gil 19 Contact: Mr Silver JUNG 08381 SEOUL Phone: +82 28669005 South Korea Cell: +82 1053767086 [email protected] www.medicalsnj.com

SNJ is a manufacturer for medical and aesthetic device.

It was founded in 1998 and have been supplying medical laser systems after getting certified as a medical device manufacturer from KFDA in 1999. Now we are exporting our products to 20 countries in the world. We have focused ultra-pulse technology for last 19 years so that our CO2 laser system is the best one in Korea and also we are getting good feedbacks from overseas hospitals and doctors. SNJ is small but will be a strong global company for providing new medical and aesthetic solutions by trying to have more clinical studies and better technical researches with our quality laser technology and production experiences.

Section 1, Xintaiwu Road, No SPIRIT SCIENTIFIC CO., LTD Booth C34 99 Contact: Ms Exia WANG Xizhi District Phone: +886 226972122 221 NEW TAIPEI Cell: +886 226972122 Taiwan [email protected] www.sslab.com.tw HOSTING

UNIVERSITY CERTIFICATE ON AESTHETICS 8 -9 OF THE FACE NOVEMBER 2019 _ GRIMALDI FORUM MONACO

UNDER THE HIGH PATRONAGE OF H.S.H. PRINCE ALBERT II OF MONACO

WWW.EUROMEDICOM.COM UNIVERSITY INSTITUTE CERTIFICATE ON AESTHETICS OF THE FACE

AR OF

8 -9-10 NOVEMBER 2019 _ GRIMALDI FORUM MONACO FACUL OF MEDICINE NICE

WWW.EUROMEDICOM.COM --- STARNIC Booth C26 100 TAIPEI Contact: Ms Doris HSU Taiwan Phone: +886 223899929 Cell: +886 912903686 [email protected] www.starone.com.tw/events/3DFacial

1f., No.10, Ln. 31, Sec. 1, SUNMAX BIOTECH Booth A25 Huandong Rd Contact: Ms. Tu Xinshi Dist Phone: +886 6-505-3288#311 744 TAINAN Cell: +886 929086218 Taiwan [email protected] www.sunmaxbiotech.com

Founded in 2001, with technology out of the benchmarking collagen experts from United States, Sunmax has grown into a highly recognized, public-listed biomedical company in Taiwan. With the capability to develop, manufacture and market high standard collagen-base medical devices, Sunmax is dedicated to have more and more patients to benefit from our innovations in the field of regeneration. Product's descriptionï¼Âš FACIALGAINTM is an injectable dermal filler utilizes Sunmax DUO technology to create a professionally administered, injectable treatment for soft tissue deficiencies, especially facial wrinkles. FACIALGAINTM mimics the function of the body's own collagen. The collagen implanted is a well conserved triple helix which is organized in the body as fibrils that bundle into fibers. The crosslinking of collagen molecule with DUO technology creates a 3 dimensional network comply native collagen which acts as skeleton of skin extracellular matrix. These intermolecular crosslinks govern the durability of collagen matrix in the body. The dual effect: Immediate result and collagenogenesis. FACIALGAINTM helps give skin its strength, structure and supporting function thru it mesh like three dimensional matrix. The fibrous mesh integrates contentedly with existed collagen tissue and migration is hardly observed once injected in the defect site. FACIALGAINTM dermal filler is injected into the skin during a minimally invasive procedure with a 27G needle. Injection of the product provides an immediate correction of facial wrinkles.

No 39, Lane 15, Sec 6, TBMS Booth A28 Minquan E Road Contact: Ms Alice RUAN 4f Phone: +886 287926000 Neihu District [email protected] 11466 TAIPEI www.tbms.com.tw Taiwan

No.305 Hua Cheng Rd. TRANSVERSE INDUSTRIES CO., LTD Booth A43 Hsin-chuang Dist. Contact: Ms Connie WANG New Taipei Phone: +886 2-85218692 Taiwan Cell: +886 926345499 [email protected] www.transverse.com/

Transverse now offers an extensive range of ISO13485,CE 0434 and FDA approved laser products which it exports worldwide, particularly targeting the European, U.S. and Asian markets. Its lineup includes laser modules, laser pointers, laser levels, medical health care products and much more. Transverse Industries invests a large amount of capital and manpower in R&D, enabling the company to release new laser products onto the market every three months. A cooperative effort with Taiwan's national research organization, which pooled both financial and personnel resources, has resulted in the development of a green laser module, designed for industrial and medical applications. 3f-1,328,gancheng St. UGINTECH CORPORATION Booth A48 40843 TAICHUNG Contact: Ms May CHANG Taiwan Phone: +886 4-22512375 Cell: +886 422512502 [email protected] www.ugintech.com.tw

ã€Â•CLATUU Freezing Fat Awayã€" Powerful cooling up to -9 ºC, which targets adipocytes to trigger apoptosis naturally in non-invasive, non-surgical, no wound, no pain, and help reduce the fat thickness of treatment. ã€Â•ULTRAFORMER IIIã€" The new technology of high intensity focused ultrasound 4/7MHz 1.5/3/4.5mm Micro Focused Ultrasound & 2 MHz 6/9mm Marco Focused Ultrasound To reinforce the focus on the face deeply, has lifting and tightening effect, can be applied to lift both cheek laxity and tight skin, and achieve tightening effect for floppy jawline, abdomen and thigh. The upgrading function is more complete and comprehensive to meet more needs of patients not only provides precise and effective therapeutic effects, but also makes the process feel more comfortable and satisfying.

#804 Shin-han It Tower ULTRA V Booth A34 19 Sangwon-gil, Seongdong-gu Contact: Mr Semin KIM Seoul Phone: +82 25393450 South Korea [email protected] www.ultrav.co.kr

ULTRA V Co., Ltd. is a company manufacturing and distributing special polydioxanone(PDO), an absorbable thread used in medical applications such as sutures. We are also expanding our enterprise field through handling cosmetic and medical device business. We are diversifying our business by manufacturing and distributing more effectual and safe products through the network from Dermaster Clinic, an aesthetic clinic we hold clinical relationship. The special polydioxanone(PDO) well known for Ultra V-Lifting is the typical brand of Ultra V Co., Ltd. and the use of this product is taking a major step forward through diverse operating techniques. It has the strong advantage for it's simple operation and maximized rejuvenation effect. Ultra V Co., Ltd. is taking the head in developing much more cosmetic products as the leader in aesthetic business. Ultra V Co., Ltd. Lead to product development as a leader in cosmetics and medical devices industry.

8f, No.4, Sec.1, Zhongxiao W. USHIO Booth A16 Rd. Contact: Jian Hua-Jiang Zhongzheng Dist. Phone: +886 2-2312-3358 10041 TAIPEI Cell: +886 963038115 Taiwan [email protected] www.ushio.com.tw

USHIO Inc. was established in 1964. The Biomedical Division consists of the Biomedical BU, which handles medical devices that use light in applications such as skin treatmentï¼ÂˆUV308ï¼Â‰ and blood analysisï¼ÂˆPointreaderï¼Â‰. And we also supply medical skincare products to more than 3000 medical institutions across Japan.

Fl. 10, No. 646, Section 5, V8LASER Booth A58 Chongxin Road Contact: Mr Tim YANG Sanchong District Phone: +886 2 8512-2511#201 241 NEW TAIPEI Cell: +886 905126602 Taiwan [email protected] www.v8laser.com.tw 2019 IC INTERNATIONAL CONGRESS OF AESTHETICD DERMATOLOGY

22-23 NOVEMBER 2019 PRE-CONGRESS 21 NOVEMBER BANGKOK CONVENTION CENTRE AT CENTRALWORLD

ORGANIZED IN COOPERATION WITH THE OFFICIAL DST - DERMATOLOGICAL SOCIETY OF THAILAND

PART OF THE A MWC MONACO IN PARTNERSHIP WITH WWW.EUROMEDICOM.COM 10 Tannery Lane #01-01 VIDIVICY PTE LTD Booth A50 347773 SINGAPORE Contact: Ms Min Min WAH Singapore Phone: +886 978553232 [email protected] www.vidivicy.sg

Vidivicy is an aesthetic medical device distributor headquartered in Singapore with presence in Taiwan and a representative office in Hong Kong.

For over ten years, our senior management of Vidivicy has provided optimal aesthetic solutions, distributing award-winning products from our global suppliers to aestheticians, physicians, beauticians, and patients. We anticipate and respond to changes in patient needs and market demand by expanding our portfolio and sales force.

Vidivicy is also dedicated to improving our clients and markets through extensive education and training. We have hosted numerous seminars, workshops, and exhibitions educating our physicians, beauticians, patients, and consumers on developing trends in the aesthetics market and the appropriate use of state of the art products.

We have built an extensive physician network facilitating the transitioning of numerous physicians from different medical practices into the aesthetician field, firmly establishing us a foothold extending past the aesthetician market and into other medical domains.

No. 298 Ruiguang Road WOH MEDICAL Booth A30 4f-1 Contact: Ms Melissa LIN Neihu Dist Phone: +886 226572968ext246 11491 TAIPEI [email protected] Taiwan www.wohmedical.com

Woh Medical Co., Ltd. Is located in Taipei Neihu Technology Park and presenting several world-renowned brands. Our managers are all well-experienced in this field over decade. Woh Medical are specialized in marketing, distributing, managing of dermal filler hyaluronic acid injector, aesthetic medical devices/consumables, laser/light-based technologies, surgical imaging system, diagnostic system, and cosmetics in Taiwan market. By specialty division, we provide hearty and professional services to our customers. Woh Medical is composed by three business units - Aesthetic Medicine, Laser-based Medicine and Preventive Medicine. For Aesthetic Medicine division, focuses on body contouring devices, dermal filler injector and cosmetics. The majority of Laser-based Medicine division are variety of laser, radio frequency and IPL. For Preventive Medicine we provide surgical imaging system, ultrasound diagnostic system and intra-articular hyaluronic injector and so on. Our purpose is to deliver an excellent experience in our service. To achieve so, we carefully choose and introduce cutting-age products from Asia, Europe and the United State. By launching and boosting brand awareness of these products, we turn our values into customers' competitive advantage. This make Woh Medical become doctors favorite partner. The core philosophy of Woh Medical: "Innovation, Integrity and Sustainable Operation". To keep up with rapid development of the market and stay competitive, we wish to achieve "the Best marketing Team in Medical field". By creating the needs and provide the best services to our clients consistently and through our strong connection between original equipment manufacturer and the customers, we established a full supply chain for prolong competition advantage and create all kinds of new opportunities of medical market in Taiwan.

.rm.2, 4f, No.936 ,sec. 4, YI CHENG BIOTECH Booth C5 Taiwan Blvd Contact: Mr.Dickson Hsieh Xitun Dist Phone: +886 4-24628876 407 TAICHUNG Cell: +886 927802009 Taiwan [email protected]

We are a young company founded in 2014. Established by a group of professional engineers and sales people with more than 10 years Of Medical aesthetic device sales, marketing and service experience. We have passion, professionality, vitality and Innovation. We keep our growth year by year . 1191 Sec.1 Chungshan Rd. YUNGSHIN PHARM IND. CO. LTD Booth A47 Tachia Contact: Ms Pei-chun Chen 43744 TAICHUNG Phone: +886 4-26875100 ext562 Taiwan Cell: +886 97888357 [email protected] www.ysp.com.tw

Yung Shin Pharmaceutical - A decent guardian of health From a Pharmacy store in the early 60's, we have grown into a mid-sized global pharmaceutical firm with wide-spread footprints and GMP compliance (US, EU, Japan, Canada, and Australia). Yung Shin an unique company with diverse capabilities in R&D, manufacturing and marketing, serves as a great candidate for partnership in both manufacturing and marketing.

940 Lincoln Rd #307 ZERO GRAVITY SKIN Booth C13 33139 MIAMI BEACH Contact: Ms Miya SHOSHAN Florida Cell: +1 972547002364 United States [email protected]

ZERO GRAVITY was founded with one principle in mind: to develop and deliver the safest and most effective anti-aging facial products to consumers across the globe. Zero Gravity is proud to be a prolific leader in the aesthetic devices market.

ZERO GRAVITY is committed to produce the most effective system of LED light therapy (light emitting diodes) for facial skin rejuvenation in the industry. Backed by medical science but specifically modified to allow for aesthetic-only treatments, the sophisticated science behind infrared light therapy is supported by many leading board-certified dermatologists and plastic surgeons across the globe.

PerfectioTM is an FDA-cleared Class II medical device.

& BOOTH NUMBERS

AE+ SOLUTION B18 MENARINI TAIWAN A45

ACL BIOMEDICAL B17 MERZ AESTHETICS C10

ALLERGAN A49 META BIOMED C12

AMMON INTERNATIONAL INC A21 MIRADRY A10

APYX MEDICAL C14 MONA FREMA A22

AROMASE A15 MYGUARD CO LTD A26

BAUSCH & LOMB C15 NEOASIA TAIWAN A31

BEAUTYCOM C20 OPATRA LTD A13

BIONET RE.O. A44 PINE BM B7

BP BIOTECHNOLOGY A19 POWER SAPLING CO., LTD A14

CLOVERS MEDTECH C11 QUANTA SYSTEM SPA A29

COLLAMATRIX C23 RENAISSE MEDICARE CO LTD C22

DENSO SCIENTIFIC A42 SCIENTIS APAC PTE LTD B25

DERMACARE C1 SCITON A33

DMK PARA-MEDICAL SKIN REVISION C18 SESDERMA A27

DYNAMIC MEDICAL TECHNOLOGIES C19 SNJ CO., LTD C41

FOTONA C6 SPIRIT SCIENTIFIC CO., LTD C34

GAIA GENOMICS C33 STARNIC C26

GAIE C9 SUNMAX BIOTECH A25

GALDERMA TAIWAN A9 TBMS A28

HO-CHI MEDICAL BOOK B4 THE HYDRAFACIAL COMPANY C2

INCRES AESTHETICS LABORATORY CO. C31 TRANSVERSE INDUSTRIES CO., LTD A43

INNOAESTHETICS A59 UGINTECH CORPORATION A48

INSTITUTE HYALUAL SWITZERLAND A60 ULTRA V A34

JEISYS A52 USHIO A16

JING FUNG B24 V8LASER A58

JOHNSON & JOHNSON A11 VIDIVICY PTE LTD A50

JTRUE C40 WOH MEDICAL A30

LEADER BOOK B3 YI CHENG BIOTECH C5

LIFE SCIENCE A17 YUNGSHIN PHARMA A47

L'OREAL TAIWAN C3 ZERO GRAVITY SKIN C13

LUMENIS C17

OTHER SUPPORTING COMPANIES CANDELA MYLAN TAIWAN LEVEL 1 LEVEL 2 LEVEL 3