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College of Arts and Sciences – FY2017 Research Abstracts ART, GRAPHIC DESIGN and ART HISTORY

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College of Arts and Sciences – FY2017 Research Abstracts ART, GRAPHIC DESIGN and ART HISTORY Fiscal year 2017 research abstracts College of Arts and Sciences – FY2017 Research Abstracts ART, GRAPHIC DESIGN AND ART HISTORY Virile Roots, Generative Earth: Chinese Rhizomes in Florentine Fertility Treatments The project examines Chinese-grown herbal drugs in medical texts and fertility treatments during the late sixteenth-century, focusing on the Chinese root galangal. Sponsor: Villa I Tatti, Harvard University Center for Italian Renaissance Studies PI: Irene Backus Folding and Unfolding the Late Medieval Physician’s Almanac Research in the UK to closely examine the material aspects of numerous fifteenth-century physician’s folding almanacs. Almanacs were not simply a collection of useful texts: they were worn on the body, touched habitually, and manipulated like other scientific instruments. Sponsor: Oklahoma Humanities Council PI: Jennifer Borland Window Gazes: Camera Obscura Photographs from the Doel Reed Center for the Arts Sponsor: Hargis Fellowship, Doel Reed Center for the Arts, Talpa, NM PI: Andy Mattern Oklahoma Visual Arts Fellowship These awards are intended to reward qualified artists with outstanding vision and are chosen by a guest curator from applications submitted by the artists. Sponsor: Oklahoma Visual Arts Coalition (OVAC) PI: Andy Mattern Shelter: A photography project to visualize time spent underground in Oklahoma storm cellars. Gelatin Silver Prints, Various Sizes: 8x10, 11x14, 16x20. Sponsor: Oklahoma Visual Arts Coalition (OVAC) PI: Andy Mattern Waiting: A six-foot rotating color wheel inspired by the cursor that appears when a computer program begins to crash. Archival Pigment Ink Prints and low-speed motor, 72″ x 72″ x 1″ Sponsor: Oklahoma Visual Arts Coalition (OVAC) PI: Andy Mattern Gardiner Gallery Exhibitions Series of exhibitions in the Gardiner Gallery of Art in the Department of Art, Graphic Design and Art History. Sponsor: Oklahoma Arts Council PI: Rebecca Brienen Art, Community, and Salvation in Colonial Mexico Research on the art and visual culture of colonial Mexican confraternities (religious brotherhoods). The aim is two-fold: 1) to better understand the significance of chapels, oratories, sculptures, paintings, and engravings for confraternities and 2) to gauge the importance of colonial corporate piety for the history of art. Book is under contract. Sponsors: Oklahoma State University, Arts and Sciences Research Fellowship (ASR +1) PI: Cristina Cruz González Centering Modernism: J. Jay McVicker and Postwar American Art Centering Modernism takes a close look at the innovative artwork of Oklahoman J. Jay McVicker (American, 1911-2004) in the context of international modernism and the coastalization of American art criticism after the Second World War. Sponsors: National Endowment for the Arts, OSU Research, OSU Library PI: Louise Siddons The Art of Asian Languages The Art of Asian Languages is an exhibition of forty works that explores intersections between art and language in contemporary East Asian culture. In Asia, writing and calligraphy have also led directly to the development of many other forms of art, including book-making, seal carving, and papercuts. The exhibition offers a fresh look at an imaginative and ambitious use of languages in the service of the visual arts. Sponsor: Oklahoma Humanities Council Major Grant for Exhibitions PI: Shaoqian Zhang Rapid Visual Prototype Through Virtual Reality for Graphic Design The visual prototype through virtual reality allowed the graphic design concept to be tested in a cost-effective environment with a 360-degree view of the project before its final production. Sponsor: School of Entrepreneurship, Oklahoma State University PI: Phil Choo Tulsa Artist Fellowship Established by the George Kaiser Family Foundation, the Tulsa Artist Fellowship recruits visual and literary artists to Tulsa, Oklahoma, where they have creative freedom to pursue their craft and contribute to a thriving art community. Sponsor: George Kaiser Foundation PI: Chris Ramsay Pigment and Paint Formulations for Oklahoma Landscapes Sponsors: Sam and Adele Golden Foundation for the Arts, New Berlin, NY and Oklahoma Visual Arts Coalition Education Grant, Oklahoma City, OK PI: Elizabeth Roth CHEMISTRY Derivation of Heteroarotinoid Systems Related to SHetA2 The development of methodology to obtain oxygen- and nitrogen-containing heteroarotinoids for the potential treatment of ovarian cancer was the focus of the project. One main objective was to generate compounds that would have increased water solubility and bind to certain proteins that would induce the cancer cells to die. Sponsor: Stephensen Cancer Center of OUHSC PI/PDs: K. Darrell Berlin, Richard A. Bunce, Field Watts, Krishna Gnanasekaran-Chemistry Studies of Ovarian Cancer The investigation was centered upon the synthesis of pyridine-containing heterocycles for the treatment of ovarian cancer. Several different groups were employed to join together the heterocyclic units in an effort to improve the binding of the compounds to certain proteins in the human body. It was reasoned that binding to selected proteins could result in cancer cells being destroyed. Sponsor: OSU Foundation PI/PDs: K. Darrell Berlin, Richard A. Bunce, Kevin Meraz-Chemistry Chemical Tools for Perturbing Iron Homeostasis in P. aeruginosa This is a collaboration with a group at the University of Kansas, which seeks to exploit a novel vulnerability in Gram-negative bacteria. Bacterioferritin is a protein that stores iron as Fe3+ in the body. A second protein normally binds to the outer surface of this protein and facilitates electron transfer from a third protein to the inner cavity, where Fe3+ is reduced to Fe2+. The resulting Fe2+ provides an energy source for the bacteria. The goal is to develop compounds that will block the binding site on bacterioferritin and prevent this process. Without Fe2+, bacterial cells have no energy source and eventually die. Sponsor: National Institute of Allergy and Infectious Diseases of the NIH PI/PDs: Mario Rivera (KU) and Richard A. Bunce (OSU) Application of Infrared Imaging and Chemometrics to Facilitate the Forensic Examination of Automotive Paints In the forensic examination of automotive paint, laboratories hand-section each layer and present each separated layer to the spectrometer for analysis which is time consuming. In addition, sampling too close to the boundary between adjacent layers is also a problem as it produces an infrared spectrum that is a mixture of two layers. These problems will be addressed by collecting concatenated infrared data from all layers in a single analysis by scanning across the cross-sectioned layers of the paint sample using an infrared imaging microscope. Decatenation of the concatenated IR data is achieved using multivariate curve resolution techniques to obtain a “pure” infrared spectrum of each paint layer. Sponsor: National Institute of Justice PI/PD: Barry K. Lavine Variable Selection for Remedying the Effects of Uncontrolled Variation in Data Driven Predictions This research is aimed at reducing the cost-of-ownership of calibration and classification models that have become increasingly common in process monitoring, quality assurance and quality- by-design applications by studying the ways in which these models fail and by searching for ways to stabilize the modeling. This project is aimed at investigating fundamental issues important to chemical modeling in modern measurement science. Methods for automated identification of the portions of the chemical responses that best model the system will be investigated. The broader impacts of this project include the improvements in efficiency and performance from improved and more reliable chemical models for production and quality assurance. Sponsor: National Science Foundation PI/PD: Barry K. Lavine Development and Validation of High Performance Liquid Chromatography Method for Quantitative Determination of 4-hydroxybenzoate and Related Renal Cell Carcinoma Biomarkers in Human Urine Renal Cell Carcinoma (RCC) is a disease that causes malignant cells to form in tubules of the kidney. RCC, the third most common form of genitourinary cancer, is a disease which is asymptotic in its initial stages. Patients are often diagnosed with RCC at the terminal or metastatic stage. At present, RCC has the highest mortality rate of any urological tumor. To improve the prognosis for patients suffering from RCC, early detection and treatment through the development of a methodology based on analysis of biological fluids (e.g. urine and plasma) for molecular markers characteristic of RCC in its early stages is desirable. An obvious advantage of this approach to cancer prescreening is that urine and plasma samples are inexpensive and readily accessible. A reversed phase liquid chromatographic method will be developed to simultaneously detect and quantify creatinine, quinolinic acid, gentisic acid and 4- hydroxybenzoic acid in urine. These four bio-markers are present in relatively high concentrations in urine. Sponsor: National Institutes of Health (subcontract from University of Central Oklahoma) PI/PD: Barry Lavine (co-PI) Electrochemical and Optical sensors/arrays for Diabetes Diabetes is an emerging epidemic condition worldwide. A recent survey by the American Diabetes Association revealed that nearly 29 million adults and children in the United States had diabetes (8.3 % population), and about 86 million people were estimated to have pre- diabetes (a condition before type-2 diabetes). Challengingly, the presence of ultra-low levels
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