Guidelines for Management of Neurogenic Bowel Dysfunction in Individuals with Central Neurological Conditions
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Positive Cases in Suspected Cauda Equina Syndrome
Edinburgh Research Explorer The clinical features and outcome of scan-negative and scan- positive cases in suspected cauda equina syndrome Citation for published version: Hoeritzauer, I, Pronin, S, Carson, A, Statham, P, Demetriades, AK & Stone, J 2018, 'The clinical features and outcome of scan-negative and scan-positive cases in suspected cauda equina syndrome: a retrospective study of 276 patients', Journal of Neurology, vol. 265, no. 12. https://doi.org/10.1007/s00415- 018-9078-2 Digital Object Identifier (DOI): 10.1007/s00415-018-9078-2 Link: Link to publication record in Edinburgh Research Explorer Document Version: Publisher's PDF, also known as Version of record Published In: Journal of Neurology Publisher Rights Statement: This is an open access article distributed under the terms of the Creative Commons CC BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 04. Oct. 2021 Journal of Neurology (2018) 265:2916–2926 https://doi.org/10.1007/s00415-018-9078-2 ORIGINAL COMMUNICATION The clinical features and outcome of scan-negative and scan-positive cases in suspected cauda equina syndrome: a retrospective study of 276 patients Ingrid Hoeritzauer1,2,5 · Savva Pronin1,5 · Alan Carson1,2,3 · Patrick Statham2,4,5 · Andreas K. -
Cardiovascular Collapse Following Succinylcholine in a Paraplegic Patient
ParajJleg£a (I973), II, 199-204 CARDIOVASCULAR COLLAPSE FOLLOWING SUCCINYLCHOLINE IN A PARAPLEGIC PATIENT By J. C. SNOW,! M.D., B. J. KRIPKE, M.D. , G. P. SESSIONS, M.D. and A. J. FINCK, M.D. University Hospital, Boston, DeKalb General Hospital, Decatur, Georgia, and Boston University School of Medicine, Boston, Massachusetts 02118 INTRODUCTION SEVERAL reports have been presented that have discussed cardiovascular collapse following the intravenous infusion of succinylcholine in patients with burns, massive trauma,tetanus, spinal cord injury, brain injury,upper or lower motor neuron disease,and uraemia with increased serum potassium. The purpose of this article is to report a spinal cord injured patient who developed cardiac arrest following administration of succinylcholine, possibly due to succinylcholine-induced hyperkalaemia. The anaesthesia management during the course of subsequent surgical procedure proved to be uneventful. CASE REPORT On 7 December 1971, a 20-year-old white man was admitted to the hospital after he fell 50 feet from a scaffold to the ground. He was reported to have been in good health until this accident. His legs and outstretched hands absorbed the major impact. No loss of consciousness was reported at any time. Neurologic examination revealed absent function of muscle groups in the distribution distal to L4, including the sacral segments. There were contractions of both quadriceps muscles in the adductors of the legs. The legs were held in flexion with no evidence of function in his hip abductors, extensors, knee flexors or anything below his knee. He had intact sensation over the entire thigh and medial calf. He had no apparent abdominal or cremasteric reflexes, no knee or ankle jerks, no Babinski responses, and no sacral sparing. -
The American Society of Colon and Rectal Surgeons' Clinical Practice
CLINICAL PRACTICE GUIDELINES The American Society of Colon and Rectal Surgeons’ Clinical Practice Guideline for the Evaluation and Management of Constipation Ian M. Paquette, M.D. • Madhulika Varma, M.D. • Charles Ternent, M.D. Genevieve Melton-Meaux, M.D. • Janice F. Rafferty, M.D. • Daniel Feingold, M.D. Scott R. Steele, M.D. he American Society of Colon and Rectal Surgeons for functional constipation include at least 2 of the fol- is dedicated to assuring high-quality patient care lowing symptoms during ≥25% of defecations: straining, Tby advancing the science, prevention, and manage- lumpy or hard stools, sensation of incomplete evacuation, ment of disorders and diseases of the colon, rectum, and sensation of anorectal obstruction or blockage, relying on anus. The Clinical Practice Guidelines Committee is com- manual maneuvers to promote defecation, and having less posed of Society members who are chosen because they than 3 unassisted bowel movements per week.7,8 These cri- XXX have demonstrated expertise in the specialty of colon and teria include constipation related to the 3 common sub- rectal surgery. This committee was created to lead inter- types: colonic inertia or slow transit constipation, normal national efforts in defining quality care for conditions re- transit constipation, and pelvic floor or defecation dys- lated to the colon, rectum, and anus. This is accompanied function. However, in reality, many patients demonstrate by developing Clinical Practice Guidelines based on the symptoms attributable to more than 1 constipation sub- best available evidence. These guidelines are inclusive and type and to constipation-predominant IBS, as well. The not prescriptive. -
A Cauda Equina Syndrome in a Patient Treated with Oral Anticoagulants
Paraplegia 32 (1994) 277-280 © 1994 International Medical Society of Paraplegia A cauda equina syndrome in a patient treated with oral anticoagulants. Case report l l l 2 l J Willems MD, A Anne MD, P Herregods MD, R Klaes MD, R Chappel MD 1 Department of Physical Medicine and Rehabilitation, 2 Department of Neurosurgery, A.z. Middelheim, Lindendreef 1, B-2020 Antwerp, Belgium. The authors report a patient who was on oral anticoagulants because of mitral valve disease and who developed paraplegia from subarachnoid bleeding involv ing the cauda equina. The differential diagnosis, investigations and treatment of the cauda equina syndrome are described. Keywords: cauda equina syndrome; anticoagulants; subarachnoid haemorrhage; mitral valve disease. Case report A 32 year old woman from Chile presented with a complete paraplegia. She claimed that the paraplegia had developed progressively over 8 months. Initially she had paraesthesiae in her feet, followed by progressive paresis of both legs, beginning distally, over a period of 3 months. Two months after the onset of illness she complained of bladder incontinence. There was no history of trauma or low back pain. Clinical examination in our hospital revealed a flaccid paraplegia at L1 level, and loss of sensation from the groins to the feet, including saddle anaesthesia. The knee and ankle jerks were absent. The anal sphincter was atonic. She had an indwelling urethral catheter, and she was faecally incontinent. Myelography and a CT scan were carried out, and a space-occupying lesion at the level of T12-L4 (Figs 1, 2) was defined. Surgical ex ploration was done to determine the cause. -
On Lumbar Disc Herniation – Aspects of Outcome After Surgical Treatment
From the Dept. of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institutet and the Dept. of Clinical Science and Education, Södersjukhuset, Karolinska Institutet Stockholm Sweden On Lumbar Disc Herniation – Aspects of outcome after surgical treatment Peter Elkan Stockholm 2017 1 The frontpage picture is published with license from: Zephyr/Science Photo Library/IBL http://www.sciencephoto.com/ All previously published papers were reproduced with permission from the publisher. Published by Karolinska Institutet. Printed by E-PRINT © Peter Elkan, 2017 ISBN 978-91-7676-712-2 2 Institutionen för klinisk vetenskap, intervention och teknik, Enheten för ortopedi och bioteknologi, Karolinska Institutet On Lumbar Disc Herniation – Aspects of outcome after surgical treatment AKADEMISK AVHANDLING som för avläggande av medicine doktorsexamen vid Karolinska Institutet offentligen försvaras i Aulan, 6 tr, Södersjukhuset Sjukhusbacken 10, Stockholm Fredag 19 maj, kl 09:00 Av Peter Elkan Handledare Opponent Docent Paul Gerdhem Enheten för ortopedi Docent Bengt Sandén Institutionen för och bioteknologi Institutionen för klinisk kirurgiska vetenskaper vetenskap, intervention och teknik Uppsala Universitet Karolinska Institutet Bihandledare Betygsnämnd Professor Sari Ponzer Institutionen för klinisk Professor Olle Svensson Institutionen för forskning och utbildning, Södersjukhuset kirurgi och perioperativ vetenskap Karolinska institutet Umeå Universitet Med dr Ulric Willers Institutionen för klinisk Professor Lars Weidenhielm Institutionen för forskning och utbildning, Södersjukhuset molekylär medicin och kirurgi Karolinska institutet Karolinska Institutet Adj. professor Rune Hedlund Institutionen för Docent Gunnar Ordeberg Institutionen för kliniska vetenskaper kirurgiska vetenskaper Sahlgrenska Akademin Uppsala Universitet Stockholm 2017 3 4 To my dear family, all patients suffering from sciatic pain and all patients who have contributed with data in this project. -
Guidelines for the Use of Rectal Irrigation
CV 412N professional:Layout 1 03/03/2009 10:57 Page 1 Guidelines for the use of Rectal Irrigation (Healthcare Professionals) CV 412N professional:Layout 1 03/03/2009 10:57 Page 2 CV 412N professional:Layout 1 03/03/2009 10:57 Page 3 Preface Dear Colleague It is always a little daunting introducing a new procedure into your clinical practice. There are always questions and some uncertainties. For this reason the bowel continence team at St Mark's Hospital have decided to share their guidelines on rectal irrigation with others. There is too much re-inventing of wheels in today's health service. We are not claiming that this is the last word on irrigation: there is always room for flexibility and adaptation. With experience, our practice may well change and develop over years to come. But for now, this is our clinical practice, which we are happy for you to use and adapt. Feedback or comments would be most welcome. Christine Norton. Burdett Professor of Gastrointestinal Nursing St Marks Hospital, London March 2009 SUPPORTED BY © St Mark's Hospital Continence Service 2009 CV 412N professional:Layout 1 03/03/2009 10:57 Page 4 Background Faecal incontinence is a common health problem, affecting over 1% of community-dwelling adults (1;2). Chronic constipation may affect 3-5% of the population depending on the definition used (3). Most patients will respond to lifestyle modifications (such as dietary modifications), medication (constipating or laxatives as appropriate) and behavioural methods such as pelvic floor muscle training or biofeedback (3;4). But for the minority who do not respond, symptoms may impose severe ongoing restrictions on quality of life. -
Bowel Management When Taking Pain Or Other Constipating Medicine
Bowel Management When Taking Pain or Other Constipating Medicine How Medicines Affect Bowel Function Pain medication and some chemotherapy and anti-nausea medicines commonly cause severe constipation. They affect the digestive system by: Slowing down the movement of body waste (stool) in the large bowel (colon). Removing more water than normal from the colon. Preventing Constipation Before taking opioid pain medicine or beginning chemotherapy, it is a good idea to clean out your colon by taking laxatives of your choice. If you have not had a bowel movement for five or more days, ask your nurse for advice on how to pass a large amount of stool from your colon. After beginning treatment, you can prevent constipation by regularly taking stimulant laxatives and stool softeners. These will counteract the effects of the constipating medicines. For example, Senna (a stimulant laxative) helps move stool down in the colon and docusate sodium (a stool softener) helps soften it by keeping water in the stool. Brand names of combination stimulant laxatives and stool softeners are Senna-S® and Senokot-S®. The ‘S’ is the stool softener of these products. You can safely take up to eight Senokot-S or Senna-S pills in generic form per day. Start at the dose advised by your nurse. Gradually increase the dosage until you have soft-formed stools on a regular basis. Do not exceed 500 milligrams (mg) of docusate sodium per day if you are taking the stool softener separate from Senokot-S or Senna-S generic. Stool softeners, stimulant laxatives and combination products can be purchased without a prescription at drug and grocery stores. -
Non-Traumatic Rupture of the Ligamentum Flavum With
Interdisciplinary Neurosurgery 16 (2019) 51–53 Contents lists available at ScienceDirect Interdisciplinary Neurosurgery journal homepage: www.elsevier.com/locate/inat Case Reports & Case Series Non-traumatic rupture of the ligamentum flavum with symptomatic ☆ spontaneous lumbar epidural hematoma: A case report T ⁎ Ashwin G. Ramayya (MD, PhD)a, ,1, Alejandro Carrasquilla (BS)c,1, Frederick L. Hitti (MD, PhD)a, Peter J. Madsen (MD)a, Jayesh P. Thawani (MD)a, Kimberly Imbesi (MD)b, Michael Trotter (MD)b, David K. Kung (MD)a, James Schuster (MD, PhD)a a Department of Neurosurgery, The University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19103, United States b Department of Emergency Medicine, The University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19103, United States c Perelman School of Medicine, The University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19103, United States ARTICLE INFO ABSTRACT Keywords: We present a case of a healthy 31 year-old male plumber who presented to the emergency room with acute onset Ligamentum flavum rupture back pain that acutely developed after simply bending over. He developed radiculopathy and cauda equina Epidural hematoma syndrome over a period of hours. An MRI demonstrated an acute lumbar epidural hematoma and a disruption of Cauda equina syndrome the ligamentum flavum, suggesting that he may have torn the ligament with lumbar flexion. The patient was Back pain taken to the operating room for an emergent lumbar decompression and recovered full neurological function post-operatively. To our knowledge, this is the first report of a spontaneous symptomatic lumbar epidural he- matoma resulting from a non-traumatic ligamentum flavum rupture. -
Exponential Increase in Stool Crosslinking Is Mirrored in Systemic Inflammation and Associated to Fecal Acetate and Methionine
H OH metabolites OH Article The Importance of Objective Stool Classification in Fecal 1H-NMR Metabolomics: Exponential Increase in Stool Crosslinking Is Mirrored in Systemic Inflammation and Associated to Fecal Acetate and Methionine Leon Deutsch 1 and Blaz Stres 1,2,3,4,* 1 Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia; [email protected] 2 Faculty of Civil and Geodetic Engineering, University of Ljubljana, Jamova 2, SI-1000 Ljubljana, Slovenia 3 Department of Automation, Jožef Stefan Institute, Biocybernetics and Robotics, Jamova 39, SI-1000 Ljubljana, Slovenia 4 Department of Microbiology, University of Innsbruck, Technikerstrasse 25d, A-6020 Innsbruck, Austria * Correspondence: [email protected]; Tel.: +386-41-567-633 Abstract: Past studies strongly connected stool consistency—as measured by Bristol Stool Scale (BSS)—with microbial gene richness and intestinal inflammation, colonic transit time and metabolome characteristics that are of clinical relevance in numerous gastro intestinal conditions. While retention time, defecation rate, BSS but not water activity have been shown to account for BSS-associated Citation: Deutsch, L.; Stres, B. The inflammatory effects, the potential correlation with the strength of a gel in the context of intestinal Importance of Objective Stool forces, abrasion, mucus imprinting, fecal pore clogging remains unexplored as a shaping factor for Classification in Fecal 1H-NMR intestinal inflammation and has yet to be determined. Our study introduced a minimal pressure ap- Metabolomics: Exponential Increase proach (MP) by probe indentation as measure of stool material crosslinking in fecal samples. Results in Stool Crosslinking Is Mirrored in reported here were obtained from 170 samples collected in two independent projects, including males Systemic Inflammation and and females, covering a wide span of moisture contents and BSS. -