HAPVIDA PARTICIPAÇÕES E INVESTIMENTOS S.A. CNPJ 05.197.443/0001-38 NIRE 233.000.392-71 MATERIAL FACT ACQUISITION OF EQUITY INTERESTS HAPVIDA PARTICIPAÇÕES E INVESTIMENTOS S.A. (B3:HAPV3) (Hapvida or Company) in compliance with current regulations, hereby informs its shareholders and the market in general that is has entered into two instruments involving the acquisition of equity interests in health entities in the Southeast and Northeast regions of Brazil (Transactions), in line with its national expansion, consolidation strategy and increased vertical integration efforts. SOUTHEAST – SÃO PAULO The Company entered into a binding proposal with the board of the Grupo HB Saúde for the acquisition of up to 100% of the group, which should be submitted for approval at their shareholders' meeting. The Grupo HB Saúde of São José do Rio Preto (SP) is composed of the following entities: H.B. Saúde S/A, H.B. Saúde Prestação de Serviços Médicos Ltda., Centro Integrado de Atendimento Ltda. and HB Saúde Centro de Diagnóstico Ltda. (Grupo HB Saúde and HBS TRANSACTION, respectively). The Grupo HB Saúde, which had annual revenues of R$310 million in 2020, is composed of one healthcare operator, the HBS Mirassol Hospital, eight outpatient units, one children's clinic, clinical and diagnostic centers, preventive and occupational medicine facilities and oncology center, all located mainly in the municipalities of São José do Rio Preto and Mirassol, in the countryside of São Paulo state. The operator of Grupo HB Saúde has a portfolio of around 128,000 beneficiaries of health plans with 67% of corporate plans and MCR of 75% in 2020 and 89% in 2019. The operator also has 24,500 beneficiaries of dental plans. The HBS Mirassol hospital currently has 31 beds, 6 of which are ICU beds. The health region that includes, in addition to São José do Rio Preto, Barretos, Fernandópolis, Votuporanga, Catanduva, Araçatuba, Três Lagoas and Uberaba, has a population of 3.8 million inhabitants and about 1.1 million beneficiaries of private health plans. The HBS TRANSACTION is synergic from a geographic and operational standpoint as the city of São José do Rio Preto is located approximately 200 km from Ribeirão Preto and Uberaba, cities with operations acquired and recently integrated by Hapvida. In the region where Grupo HB Saúde operates, Hapvida already has around 110,000 beneficiaries in health plans. The acquisition price, including some properties and excluding net cash, will be R$450.0 million for all the shares. The acquisition of Grupo HB Saúde is another important step in the strategy of growth and market share gain in the state of São Paulo and expanding the potential for vertical growth in the region. The implementation of the purchase and sale operation provided in the HBS TRANSACTION is subject to the fulfillment of suspensive conditions, including its approval at an extraordinary general meeting to be called by HB Saúde by their shareholders holding at least 50% plus one HB Saúde share. The HBS TRANSACTION is subject to the successful negotiation of the respective contractual acquisition instruments and their respective formalizations, which also involves the satisfactory conduct of legal, accounting and operational due diligence procedures. It will be submitted for consideration and approval by the regulatory bodies (Cade and ANS). NORTHEAST – BAHIA Additionally, the Company, through its wholly owned subsidiary Ultra Som Serviços Médicos S.A., signed an agreement for the purchase and sale of quotas and other covenants for the acquisition of 100% of the voting capital of Cetro - Centro Especializado em Traumatologia Reabilitação e Ortopedia Ltda. (Hospital-Dia Cetro and CETRO TRANSACTION, respectively). The Hospital-Dia Cetro, located in Alagoinhas (BA), Northeast region of the country, currently has 12 active beds and capacity for up to 16 beds, in addition to 10 doctors' offices, 2 emergency care rooms and 2 operating rooms. The Company will make investments to expand and modernize its infrastructure and upgrade machinery and equipment. The acquisition price, which includes the property’s land of 3,100 square meters and 2,000 thousand square meters of constructed area, was set at R$25.0 million. The CETRO TRANSACTION is synergic from a geographical and operational point of view, since the city of Alagoinhas is located close to Salvador, Lauro de Freitas, Camaçari and Feira de Santana, cities that already have Hapvida operations with around 348 thousand beneficiaries in health insurance. The acquisition of Hospital- Dia Cetro will not only verticalize the hospital care of the existing portfolio in Alagoinhas, with around 7,000 beneficiaries, but will also support Hapvida's organic growth plan in the short term. Finally, the Company clarifies that these Transactions will not generate withdrawal rights, pursuant to applicable law. Fortaleza, Ceará, July 7, 2021 MAURICIO TEIXEIRA Chief Financial and Investor Relations Officer .