IAEA-TECDOC-1007
Directory cyclotronsof used radionuclidefor production in Member States
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Industrial Applications and Chemistry Section International Atomic Energy Agency Wagramer Strasse5 0 10 x Bo O P A-1400 Vienna, Austria
DIRECTORY OF CYCLOTRONS USED FOR RADIONUCLIDE PRODUCTION IN MEMBER STATES IAEA, VIENNA, 1998 IAEA-TECDOC-1007 ISSN 1011-4289
©IAEA, 1998
Printed by the IAEA in Austria March 1998 FOREWORD
directore Th f cyclotronyo s use radionuclidr dfo e productio updatn e databasa th s ni f eo n eo cyclotrons that was compiled by the IAEA in 1983.
The need for the directory of cyclotrons was identified in November 1996 by a consultants group. A questionnaire was then prepared and distributed to all institutions in Member States known to the IAEA to have a cyclotron, or that were identified to be in the process of installing a cyclotron.
The directory was prepared from the information contained in the replies to the questionnaire. The data were compiled into a uniform format for individual entries. In some instances, institutions questione th l t repldial dno o yt s containe questionnairee th n di .
The directory includes most of the cyclotrons in the world that are used at least in part for radionuclide production, because institutione mosth f o t s responded. Replies were generaln i , t no , received from institutions that have cyclotrons dedicated to physics and/or material science activities.
e directorTh s compile yIAEA'e wa th y db s Industrial Application Chemistrd an s y Section, Divisio Physicanof Chemicaand l l Sciences IAEThe . gratefuAis personall to l s that co-operatedand responded to the questionnaire and to those persons who further assisted in this effort by identificatio contacy ke f no t person institutionse th t sa .
Informatio existinn o n g facilitie t includeno s d planne an thin i d w s dne directory n o d an , cyclotron installations to be used for radionuclide production, may be forwarded to the Industrial Applications and Chemistry Section. EDITORIAL NOTE
In preparing this publication for press, staff of the IAEA have made up the pages from the original manuscripts as submitted by the authors. The views expressed do not necessarily reflect IAEA, the thosegovernments the of nominatingthe of Member nominatingStatesthe or organizations. Throughout textthe names Memberof States retainedare theyas were when textthe was compiled. The use of particular designations of countries or territories does not imply any judgement by publisher,the legalthe IAEA,to the status as suchof countries territories,or of their authorities and institutions or of the delimitation of their boundaries. The mention of names of specific companies or products (whether or not indicated as registered) does not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement or recommendation on the pan of the IAEA. CONTENTS
INTRODUCTION...... 7 .
ARGENTINA...... 21 AUSTRALIA...... 25 BELGIUM...... 31 BRAZIL...... 47 CANADA...... 3 5 . CHINA...... 67 CZECH REPUBLIC...... 77 DENMARK...... 79 EGYPT...... 83 FINLAND...... 85 FRANCE...... 91 GERMANY...... 99 HUNGARY...... 139 INDIA...... 141 INDONESIA...... 143 IRAN, ISLAMIC REPUBLIC OF ...... 145 ISRAEL...... 147 ITALY...... 149 JAPAN...... 161 KAZAKSTAN...... 227 KOREA, REPUBLIC OF...... 229 NETHERLANDS ...... 235 NORWAY...... 249 POLAND...... 251 ROMANIA...... 255 RUSSIAN FEDERATION...... 257 SAUDI ARABIA...... 265 SOUTH AFRICA...... 267 SPAIN ...... 269 SWEDEN ...... 273 SWITZERLAND...... 275 SYRIAN ARAB REPUBLIC...... 281 UNITED KJNGDOM...... 283 UNITED STATES OF AMERICA ...... 301
SAMPL QUESTIONNAIRE...... 43F EO 3 INTRODUCTION
The directory of cyclotrons used for radionuclide production is an update of the data base on cyclotrons compiles thawa t Internationae th 198n di y 3b l Atomic Energy Agency directore Th . y contains technical, utilizatio d administrativan n e information supplief e IAEo th s Aa o t d October 1997.
The directory was prepared through information collected by questionnaires sent to institutions that either have a cyclotron, or that were identified to be in the process of installation of a cyclotron.
The director consideres yi includo dt e cyclotron e mosth f worlo te th f dso tha usee ar tleast da t in part for radionuclide production because most of the institutions responded. Replies were not received froinstitutiono mtw s that pioneere developmene th n di f cyclotroo t n radionuclides, certain commercial interests, and some of the new facilities that have recently purchased a cyclotron but have not begun the installation. The questionnaire was, in general, not completed by institutions that have cyclotrons dedicated to physics and/or material science activities. Certain of the institutions constructing superconducting cyclotron r medicafo s nuclead an l r physics applications responded even though not yet involved in radionuclide production initiatives.
The directory is organised by alphabetical listing of the Member States. There are individual entrie r eacfo s h cyclotron eve r institutionfo n s having more thae cyclotronon n e namesTh . , title/position of the persons listed in position [2] in the entries for individual countries were taken directly from the answers in the questionnaires.
The directory contains 206 entries for cyclotrons operating in 34 Member States. The largest concentration of cyclotrons for radionuclide production are located in the United States of America (66), Japan (33) and Germany (22). The largest number of cyclotrons for a single country is the United States of America. However, taken collectively there are the 48 cyclotrons located in the European Union countries that are used for medical radionuclide production. It is not surprising that cyclotrow ne e th n installation e distributear s d throughou e Membeth t r States generaln I . , newly developing a cyclotrocountrie r fo t nop s acceleratin meeo t nationae th V t gMe protonl5 >1 o t s interes multipurposa r fo t e cyclotro supplo nt y both SPET (single photon emission tomographyd )an industrial radionuclides within the country, and PET (positron emission tomography) radionuclides for local needs.
There are a significant number of entries for commercial based cyclotrons. Some of the companies provided detail production so n statistics, whereas others indicated requestee somth f eo d informatio proprietys nwa compane On . y having fou morr o r e cyclotrons decline commento dt s i t I . noteworthy to mention that several institutions commit excess beam time for either solid target irradiations for companies, or act as a distribution center of radiochemicals or radiopharmaceuticals to customers in the region of the cyclotron facility.
The expansion in number of cyclotrons during the last decade has been driven by the advent of advance medican i s l imaging instrumentation (PET, SPE mord Tan eemissio V recentlKe 1 ny51 tomography); introductio usef no r friendly compact medical cyclotrons from several companies that manufacture cyclotrons; and recent decisions that I5O-oxygen PET studies in Japan, and I8F-FDG PET studies in Germany are eligible for reimbursement by government or insurance companies.
A emerging tren integrato t s denergi w lo ea y cyclotro emissiod nan n tomography into medical imaging corporations formed by physicians in private practice. Another factor contributing to the sale f cyclotronso introductioe th s i s PETNee th f no t concep f distributioo t f positrono n emitting radiopharmaceuticals from a central cyclotron to satellite hospitals that have the imaging technology and the patients. The satellite approach is cost-effective because it is not necessary for every medical imaging centee cyclotroth operato n t a sourcr s ow n a f t short-livei eo e d radiopharmaceuticals. 18F-FDG is gaining widespread clinical acceptance. Fluorine-18 has a 110 minute half life. Nitrogen- 13 with a half life of 10 minutes in the radiopharmaceutical form as 13N-Ammonia is commercially availabl majow fe a r citiesn ei .
Figur depict1 e numbee sth f cyclotrono r s use radionuclidr dfo e production yeae th f o rd an , installation projectioe Th . installationr nfo s underwa 199n yi bases 8i d upon information suppliey db respondents and by companies that manufacturer cyclotrons.
72 74 76 78 80 82 84 86 88 90 92 94 96 98 Yea f Installatioro n
FIG. Number1. of cyclotrons installed soldor between 1972 1998.and
Tabl eI summarize characteristice sth cyclotrone th f so s thapresentle ar t y manufacturey db nin ) differene(9 t companies interestins i t I . not o gt trendnumbee e eth th n si particlef o r , beam energy of the installed cyclotron, as well as the contemporary trend in characteristics of the cyclotrons.
The IAEA is aware of 36 cyclotron facilities that are in the process of installation during 1997- 1999 facilitiew .ne e identifiee Somar th s f o e d with individual entries. However,e otheth f o r institutions currently introducin technologe gth y identifiee preferreb o t t dno formall t thiya s time. The type cyclotronf so s installationchosew ne r seee nfo b nn frosca m oldese TablTh . etI operating cyclotron was commissioned in 1948 at the University of Birmingham, UK. TABLE I. STATISTICS CONCERNING CYCLOTRONS
Number of Cyclotrons Company Model Description Operational Being installed
CTI, Inc. RDS111 1 1 MeV ff 5 10 RDS 112 1 1 MeV HT 22 1
EBCO TECHNOLOGIES
2 T I V Me 3 1 TR13 1 TR19 T I V 10-1Me 9 0 " TR19/D V Me 99 5- \ H V 10-1Me 9 TR30 15-32 MeV H* 1 1 " TR3D V 0Me 5 1 , H~ V 15-3Me 2
D.V. EFREMOV INSTITUTE
2 3 d V Me 0 1 , p V Me MGC-28 1 0
GENERAL ELECTRIC (GE)
PETtrace 16.5 MeV H", 8.4 MeV D" 8 3
ION BEAM APPLICATIONS s.a. (IBA)
CYCLONE 3 3.8 MeV d 0 4 CYCLONE 10/5 10 MeV HT, 5 MeV D" 1 2 4 7 ' D V Me 9 , CYCLONH' V Me 8 E1 18/9 6 4 V Me 8 CYCLON1 + E18 CYCLONE 30 15-30 MeV H\ 15 MeV D' 16 1 3 1 p V Me 0 CYCLON24 5 E23
JAPAN STEEL WORKS LTD. (JSW)
4 d V Me 8 , p V Me 6 1 BC168 BC1710 17MeVp, lOMeVd 8 1 " D V Me 0 1 , IT V BC20Me 0 2 1 ON BC2211 22 MeV p, 11 MeV d 1 BC3015 30 MeV p, ISMeVd 1
OXFORD INSTRUMENTS LTD.
3 7 " H V Me 2 1 OSCAR Isotrace (Superconducting) TABLE I. (CONT.) STATISTICS CONCERNING CYCLOTRONS
Numbe Cyclotronf ro s Company Model Description Operational Being installed
SCANDITRONIX MEDICAB LA
MC17 17.2MeVp,8.3MeV6 1 d 12MeV3He,16.5MeV4He MC30 30 MeV p, 15 MeV d 1 2 MC32NI ' D 8-1, V H" 15-3 6Me V 2Me 11-23 MeV 3He, 15-31 MeV 'Tie 8 MC40 D , 5-2V 10-4H 0V Me 0Me 3HeV 13-5e ,Me 10-43"H V 0Me MC50 18-52 MeV H, 9-25 MeV D 2 24-6 3HeV e ,7 Me 18-5 "H V 0Me MC60 50 MeV p 1 K130 1 6-9H',10-6 V D 0 Me V 5Me 16-17 3HeV ,3 Me 20-13 'TiV e0Me
SUMITOMO HEAVY INDUSTRIES LTD. (Sffl)
CYPRIS 325 16 MeV p, 8 MeV d 2 1 6 d V Me 0 1 , CYPRIS37p V Me 6 1 0 2 6 d V Me 0 1 , H' V Me 8 1 H 8 M1 HM12 12 MeV p, 6 MeV d 0 1 480 AVF 30 MeV p 1 AVF 680 40 MeV p 1 AVF 715 50 MeV p 1 AW 750 70 MeV p 2 AVF 930 90MeVp,35MeVd(K=110) 2 1 140= K ( ) p V Me 0 1008 W A 0 1 400= RinK ( ) , gp CyclotroV Me 0 n40 400 Ring Cyclotron 240 MeV p, (K = 540) 1 540 C 235 240 MeV ff 1
directore Th y doe t specificallsno y cite entrie cyclotronr sfo s thausee r protoar t dfo n therapy, althoug institutionw fe ha s indicated involvemen thin i t s application. Typically proton therapy nanoamper 4 proton V o t 2 Me t 0 sa require 24 eo t currents0 s7 . Therefore vere beaw th ylo mo t e du , currents therefore cyclotrons dedicated to proton therapy are not suitable for medical radioisotope production.
The questionnaires identified 39 radionuclides as being of clinical, commercial and research interest This includes 5 generator systems. Table II provides a definition of the priorities for cyclotron produced radionuclides.
The driving force for new cyclotron installations is the production of positron emitting radiopharmaceuticals for PET. However, it is significant to note that there are four cyclotrons
10 presently dedicated to production of' Pd, and that two additional cyclotrons have been ordered for production of the radionuclide which is used in brachotherapy for treatment of prostate cancer.
TABLE II. PRIORITIES FOR PRODUCTION OF CYCLOTRON RADIONUCLIDES
Application Radionuclide
PETandSllKeVSPET
Emphasis on: UC, 13N. 15O, 18F Emerging "Cu, 124I Research Interest 38K, 45Ti, 62Zn / 62Cu, 73Se, 75Br, 76Br, 82mRb, 94mTc
SPET Clinical 67Ga, M1In, I23I, 201T1
Therapeutic "Cu, 67Cu, 103Pd, 186Re, 211At
Standards and Sources ^Na, 57Co, 139Ce
Commercial -Medical 18F, 67Ga, 81R 81m/ b Kr, 103Pd, 123Xe/123I,201Pb/201Tl Emerging 124I Various 22Na, 57Co, 88Y
7 10 28 48 75 87 87m 93 Others Be, C, Mg1 V? Se, Y / Y, Mo,
11 Tabl I summarizeeII expectee th s d production yield (mCi f syntheti)o c precursorT PE f o s radiopharmaceuticals with the range of commonly used proton and deuteron energies and irradiation
recommendes a A u 5 manufacture3 e o th t y du b 0 varioue 2 ath t f o r s cyclotrons. Fluorine-18 FDG)(I8 , Oxygen-15 (Water, Oxygen, Butano Carbod an l n Monoxide), Carbon-11 (Acetate, Methionine), and Nitrogen-13 (Ammonia) are the most widely used positron emitting radiopharmaceuticals. Essentially all PET centers regularly produce ' FDG for clinical use. In additio a significann t numbe f centeo r C labelleU r d alse specifian us do F ligand18 c r fo s neuroreceptor studies. These include: I8F-DOPA, I8F-Altanserin nC-Raclopride, llC-Flumazenil, UC-WAY 100635, HC-SCH 23390, etc. Many research orientatied institutions have radiochemists developin a widg e rang f radiopharmaceuticalo e d labelean s d compound r diagnosifo r s o d an s monitoring treatments of various diseases.
TABLE III. EXPECTED PRODUCTION YIELD (mCi SYNTHETIF )O C PRECURSORT PE F SO RADIOPHARMACEUTICALS WITH SELECTED PROTON AND DEUTERON ENERGIES AND RECOMMENDES A A u IRRADIATIO 5 3 MANUFACTURE E o t TH u Y 0 D2 B T NA E TH F RO VARIOUS CYCLOTRONS*
Precursor 16 -18 MeV proton 9-10 MeV proton 12-13MeV proton 8-9 MeV deuteron 4-5 MeV deuteron
1] C02 2800 1000 1500 "CO 1400 350 1000 "CH3I 700 350 1250 nCNH 1200 250 750 U I5NH3 450 100 200 o2 1200 >150 per minute 1000 15OC 700 minutr pe e5 7 > 500 15OCO 700 > 150 per minute 500 15 OH2 1000 200 750 i«p- 800 >500 700 "FF 300
*Note: There are cyclotron gas targets available the are routinely operated at 25 to 50 uA for I5productiod Oan . c " f no
Ther reporte ear s that: 1n hou2 protonA r(1V irradiatio ) singl wita Me A n 2 u sh o 1 e5 6 recirculatin t na 98%> ( O ) 2 H g target yields > 4 Ci of 18F- Fluoride; I8 (2) The simultaneous irradiation of two targets of H2 O (> 98%) with a 18 MeV cyclotron can produce > 5 Ci of F-Fluoride.
12 Nuclear Data
The questionnaire requested information concerning the user's requirements for nuclear data. Statistics are given in Table IV. Nineteen percent (19%) of the respondents indicated that they were engage nuclean di r reaction cross section measurements respondentf . o Ove% 50 r s identified that they used reaction cross section data, thick target yields decad an , y data.
TABL DETERMINATIORESPONS. E EIV TH D QUESTIONNAIRAN O EF T O E NUS E TH N EO OF NUCLEAR DAT CYCLOTROT AA N FACILITIES engageu yo e nuclean di Ar r reaction cross section measurements? % 19 Yes No 69% No Response 12 %
Which typ nucleaf eo useu r datyo ? o ad % 1 5 s Ye Reaction Cross Sections No 13% No Response 36 %
Thick Target Yields Yes 52 % 13% No No Response% 36
Decay Data Yes 57 % No 8% No Response 35%
13 LIS CYCLOTRONF TO COUNTRY SB Y ENTRY, LOCATIOD NAN MODE CYCLOTROF LO EACT NA H INSTITUTION
Entry Location Model
ARGENTINA ARG-1 Comision Nacional De Energia Atomica (CNEA) CP-42 ARG-2 Fundacion Escuel Medicine ad a Nuclear 2 11 S RD
AUSTRALIA AUL-1 Peter MacCallum Cancer Institute AUL-2 Austin & Repatriation Medical Centre Cyclone 10/5 AUL-3 Australian Nuclear Science & Technology Organization Cyclon0 e3
BELGIUM BEL-1 Erasme Hospital Cyclon0 e3 BEL-2 VRJJE Universiteit Brussel CGR-560 BEL-3 MNS Nordion, S.A. Cyclon0 e3 BEL-4 University of Gent CGR-Me0 V52 BEL-5 U. Z. Gasthuisberg Cyclone 10/5 BEL-6 Universit Liege ed e CGR-Me0 V52 BEL-7 Universite Catholiqu Louvaie ed n Cyclone 30 BEL-8 Universite Catholique de Louvain Cyclone
BRAZIL BRA-1 Institut Engenharie ed a Nuclear CV-28 BRA-2 Institut Pesquisae ed s Energetica Nuclearese s CV-28 BRA-3 Institut Pesquisae ed s Energetica Nuclearese s Cyclone-30
CANADA CAN-1 TRIUMF CP42 CAN-2 TRIUMF TR30 CAN-3 TRIUMF TRIUMF CAN-4 TRIUMF PET Programme TR13 CAN-5 McMaster University CAN-6 Clarke Institut Psychiatrf eo y MC-17 CAN-7 Montreal Neurological Institute Cyclone 18/9
CHINA CPR-1 China Institute of Atomic Energy Cyclon0 e3 CPR-2 Beijing Normal University CS30 CPR-3 Beijing Normal University CS22 CPR-4 Zibo Wanjie Hospital PETTrace CPR-5 Shanghai Institut Nucleaf eo r Research Cyclon0 e3
CZECH REPUBLIC CZR-1 Nuclear Physics Institute U-120M
DENMARK DEN-1 PET Centre PETTrace DEN-2 University Hospital of Copenhagen MC 32-NI
14 EGYPT EGY-1 Nuclear Research Centre MGC-20
FINLAND FIN-1 Universit Helsinkf yo i Cyclone 10/5 FIN-2 Turku PET Centre MGC-20 FIN-3 Turku PET Centre Cyclone 3
FRANCE FRA-1 Centre d'Exploration et de Recherche Medicales Cypris 325 Emissior pa Positrone nd s (CERMEP) FRA-2 Centre Antoine Lacassagne FRA-3 Centre National de la Recherche Scientifique FRA-4 Service Hospitalier Frederic Joliot CGR-MeV 520
GERMANY GFR-1 Rheinisch-Westfalische Technische Hochschule RDS 111 GFR-2 Zentralklini Berkd kBa a GmbH 1 11 S RD GFR-3 Universitatsklinik der Ruhr-Universitat Bochum Cyclone 18/9 GFR-4 Forschungszentrum Rossendorf U-120 GFR-5 Forschungszentrum Rossendorf Cyclone 18/9 GFR-6 Institute for Medical Radiation Physics CV28 GFR-7 J.W. Goethe University Cyclone 18/9 GFR-8 Euro-PETGmbH PETTrace GFR-9 UKE-Cyclotron 140/TV GFR-10 Medizinische Hochschule Hannover (MHH) MC35 GFR-11 German Cancer Research Centre (DFKZ) MC32NI GFR-12 Forschungszentrum Jiilich GmbH BC1710 GFR-13 Forschungszentrum Jiilich GmbH PETTrace GFR-14 Forschungszentrum Jiilich GmbH CV28 GFR-15 Forschungszentrum Karlsruhe (FZK) CP42H GFR-16 Forschungszentrum Karlsruhe (FZK) AEG GFR-17 Max-Planck-Institut fur Neurologische Forschung MC 16 GFR-18 Technischen Universitat Miinchen RDS 112 GFR-19 Universitatsklinikum Tubingen (UKT) PETTrace GFR-20 University Hospitam lUl Cyclone 18/9
HUNGARY HUN-1 Institut Nucleaf eo r Researce th f ho MGC 20E Hungarian Academy of Sciences INDIA IND-1 Variable Energy Cyclotron Centre (VECC) VECC
INDONESIA INS-1 National Atomic Energy Agency, BATAN CS30
IRAN IRA-1 Nuclear Research Centre for Agriculture Cyclon0 e3 and Medicine (NRCAM) ISRAEL ISR-1 Hadassah University Hospital Cyclone 18/9
15 ITALY ITA-1 European Commission, ISPRA MC-40 Raffael. S . H e ITA-Institut2 e RDS112 ITA-3 Istituto Nazional Studio l r Cura l Tumorei pe o e ade i (INT) MC 17E ITA-4 Consiglio Nazionale delle Ricerche MC17 ITA-5 Universit Padovi ad a RDS 112 ITA-6 CNR Institute of Clinical Physiology PETTrace
JAPAN JPN-1 National Institute for Longevity Sciences HM-18 JPN-2 Research Institute for Brain and Blood Vessels Akita BC-168 JPN-3 National Institut Radiologicaf eo l Sciences HM-18 JPN-4 National Institut Radiologicaf eo l Sciences AVF-930 JPN-5 Daiichi Radioisotope Laboratories, Ltd. MC-40 JPN-6 Daiichi Radioisotope Laboratories, Ltd. Cyclone 30 JPN-7 Nihon Medi-Physic . LtdsCo . Chiba Facility 480P JPN-8 Nihon Medi-Physics Co. Ltd. Chiba Facility 75V 0P JPN-9 Kyushu University BC 1710 JPN-10 Fukui Medical University OSCAR5 JPN-11 Japan Atomic Energy Research Institiute CGR-Me0 V93 JPN-12 Gunma University School of Medicine BC 1700 JPN-13 Nikko Memorial Hospital RDS 111 JPN-14 Nihon Medi-Physics Co. Ltd. Hyogo Facility Cyclon0 e3 JPN-15 Nihon Medi-Physic . LtdsCo . Hyogo Facility Cyclone 30 JPN-16 Hyogo Institute for Aging Brain & Cognitive Disorders OSCAR-2 JPN-17 National Research Institut Metalr efo s BC 1710 JPN-18 Kanazawa Cardiovascular Hospital BC 1710 JPN-19 Nishina Memorial Cyclotron Centre MCY 1750 JPN-20 Nishijin Hospital BC 1710 JPN-21 Kyoto University Hospital Cypri5 s32 JPN-22 Nagoya City Rehabilitation Centre Cypri0 s37 JPN-23 Nagoya University School of Medicine BC2211 JPN-24 Osaka City University Medical School Hospital OSCAR SCC12P JPN-25 Institut Bifunctionar efo l Research HM18 JPN-26 National Cardiovascular Centre Cypri0 s37 JPN-27 Hokkaido University Hospital JPN-28 Tohohu University, (CYRIC) F AV 0 68 JPN-29 University of Tokyo Cypri0 s37 JPN-3 0 Tokyo Metropolitian Institute of Gerontology Cypris 370 JPN-31 National Centre of Neurology and Psychiatry OSCARP 12 C SC , JPN- 32 International Medical Centr Japaf eo n 20IOC B N JPN-33 fflMEDIC Imaging Centre at Lake Yamanaka HM 18
KAZAKSTAN KAZ-1 Institute of Nuclear Physics U150
KOREA, REPUBLIC OF ROK-1 Seoul National University Hospital TR-13 ROK-2 Korea Cancer Centre Hospital (KCCH) MC50 ROK-3 Samsung Medical Centre PETTrace
NETHERLANDS NET-1 Vrije Universiteit Cyclone 18/9 NET-2 Vrije Universiteit AVF NET-3 Eindhoven University of Technology (TUE) AVF
16 NET-4 Eindhoven Universit Technologf yo y (TUE) ILEC NET-5 Groningen University Hospital MC17F NET-6 Mallinckrondt Medical B.V. MCI7F NET-7 Malhnckrondt Medical B.V. Cyclon0 e3
NORWAY NOR-1 Universit Oslf yo o MC35
POLAND POL-1 Henryk Niewodniczanski Institut Physicf eo s AIC-144 POL-2 Warsaw University AVF
ROMANIA ROM-1 National Institute for Research & Development U-120 for Nuclear Physic Engineerins& gHon- a Hulubei
RUSSIAN FEDERATION RUS-1 Bakoulev Scientific Centr Cardiovascular efo r Surgery RDS-11 RUS-2 Cyclotro . LtdnCo . U-150-1 RUS-3 Institute of the Human Brain MC-17 . KhlopiG . V nRUS- Radiu4 m Institute MGC20
SAUDI ARAB REPUBLIC SAU-1 King Faisal Specialist Hospital and Research Center CS30
SOUTH AFRICA SAP-1 National Accelerator Centre (NAC) NAC
SPAIN SPA-1 Centr ComplutensT ePE e OSCAR SPA-2 Clmica Universitana de Navarra Cyclone 18/9
SWEDEN SWE-1 Uppsala University MC17
SWITZERLAND SWI-1 University Hospital Geneva Cyclone 18/9 SWI-2 Paul Scherrer Institute (PSI) Phillips SWI-3 University Hospital Zurich PETTrace
SYRIAN ARAB REPUBLIC SYR-1 Atomic Energy Commission of Syria (AECS) Cyclone 30
UNITED KINGDOM UK-1 University of Aberdeen CS-30 UK-2 University of Aberdeen 1 11 S RD UK-3 Universite Th Birminghaf yo m Nuffiel" 60 d UK-4 The University of Birmingham Radial Ridge UK-5 Wolfson Brain Imaging Centre PETTrace UK-6 MRC Cyclotron Unit MC40 MARKI I UK-7 MRC Cyclotron Unit 3D UK-8 St. Thomas Hospital 2 11 S RD UK-9 Douglas Cyclotron Unit MC-62
17 UNITED STATES OF AMERICA USA-1 Good Samaritan Hospital RDS 112 USA-2 Lawrence Berkeley National Labotratory RDS111 USA-3 Crocker Nuclear Laboratory 76" USA-4 Universit California-Irvinf yo e MC17 USA-5 Universit Californif yo Angeles Lo t aa s RDS 112 USA-6 Universit Californif yo Angeles Lo t aa s RDS 112 USA-7 University of Southern California RDS 111 USA-8 PET-Net/VAPaloAlto 2 11 S RD USA-9 Northern Californi ImaginT aPE g Centre 2 11 S RD USA-10 Yale UniversitCentrT PE eA (115AV y / ) RDS 112 USA-11 Mount Sinai Medical Centre CS-30 USA-12 St. Joseph's Hospital 2 11 S RD USA-13 Emory Universit CentrT yPE e 2 11 S RD US A-14 Theragenics Corporation Cyclone 18+ US A-15 Theragenics Corporation Cyclon+ e18 US A-16 Theragenics Corporation Cyclon+ e18 US A-17 Theragenics Corporation Cyclon+ e18 US A-18 The Queens Medical Centre RDS 111 USA-19 Medi-Physics, Inc. MC-40 USA-20 Medi-Physics, Inc. PV-750 USA-21 Medi-Physics, Inc. MC-40 USA-22 PET-Net-Chicago RDS 112 USA-23 Methodist Medical Centre of Illinois 2 11 S RD USA-24 Indiana University Cyclotron Facility K200 USA-25 Indiana University Cyclotron Facility K16 USA-26 Indiana University Hospital RDS-112 USA-27 Universit Iowf yo a MC-17F USA-28 Massachusetts General Hospital MC-1F 7 USA-29 Johns Hopkins Medical Institutions RNP-16 USA-30 National Institute of Drug Abuse (NIDA) RDS 111 USA-31 National Institute of Health CS30 USA-32 National Institute of Health JSW-1710 USA-33 University of Michingan CS-30 USA-34 Gershenson Radiation Oncology Centre KlOO-Harper USA- 35 Children's Hospita Michigaf o l n RDS-112 USA-36 National Superconducting Cyclotron Laboratory Superconducting USA-37 National Superconducting Cyclotron Laboratory Superconducting USA-38 William Beaumont Hospital RDS-112 USA-39 VA Medical Centre (1 IP) MC-40 USA-40 Saint Louis University Hospital RDS 112 USA-41 Creighton University 2 11 S RD USA-42 Medi-Physics, Inc. CS-22 USA-43 Medi-Physics, Inc. Cyclon0 e3 USA-44 Columbia Presbyterian Medical Centre RDS 112 USA-45 North Shore University Hospital MC-17F USA-46 State Universit Yorw Buffalt kNe a f yo o Cyclone 30 USA-47 Memorial Sloan-Kettering Cancer Centre CS-15 USA-48 Brookhaven National Laboratory 60" USA-49 Brookhaven National Laboratory JSW 1710 USA-50 Carolinas Medical Center RDS 112 USA-51 Duke University Medical Centre CS-30 USA-52 Bowman Gray Schoo Medicinf lo e RDS 112 Chrise USA-5Th t Hospita3 l RDS 112
18 USA-54 Case Western Reserve Universit d yan MC-17 University Hospitals of Cleveland 2 11 S USA-5RD 5 Kettering Medical Centre USA-56 Universit Pennsylvanif yo a BC3015 USA-52 11 S 7 RD Universit Pittsburf yo FacilitT PE g y USA-58 2 Universit11 S RD Tennessf yo e Medical Centre USA-59 Vanderbilt University RDS 112 Ridgk USA-6Oa e Nationa0 l Laboratory K=100 USA-61 Texas A & M Cyclotron Institute K500 USA-62 University of Texas Health Centre at Houston MC-40 USA-63 Universit Texaf yo sF Researc17 C M h Imaging Centre USA-64 Universit Washingtof yo n Medical Centre MC-50 USA-65 West Virginia University PET Centre PETTrace USA-66 University of Wisconsin RDS 112
KEXT PAOE(S) !cf t BLANK 19 ARGENTINA ARG-1
[1] Institute: Comision National Energiade Atomica (CNEA) Postal Address: Avenida del Libertador 8250 1429 Buenos Aires
Telephone: 54-1-3798150 Fax/E-mail: 54-1-4800615
[2] Person in-charge: Lie. Carmelo Rocco (Title/Position) Head of the Facility
Other senior staff: Roberta Strangis Eduardo Haro
[3] Typ cyclotronf eo : Isochronous, NegativeIon Manufacturer: The Cyclotron Corporation Model: CP-42
installationf Yearo ) (i : : 1994 majoy an (11 f ro ) reconstruction:
] [4 Particle beams available:
*H ^ * *e ; *He Dual Beams
Beam energies/Range 25 to 40 (MeV) Typical currentt in s (UA) Employet ex d 100 (HA)
Hours per week machine is in operation (excluding maintenance): The Cyclotron is not in routine operationyet
Hours per week employed in radionuclide production:
Hour weer spe k machine maintenance:
Additional application cyclotrone th f so : Investigation
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
21 ] [5 Radionuclides produced:
Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
[6] Radionuclides planned to be produced m the near future: , T 1 20 T ^ 3 18,-,67 FIII12 , T Ga, In, /„ 77
[7] Major radiopharmaceuticals produced: 20177 routine production planned from1997y Ma
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san
medicas I [9] l research/diagnosis carriesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . r[10a reactio] n cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sYe sections Thics kYe target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
22 ARGENTINA ARG-2
[1] Institute: Fundacion Escuela Medicinade Nuclear Postal Address: Garibaldi - Mendoza 405
Telephone: 54-61-201615 Fax/E-mail: 54-61-203288
[2] Person in-charge: Eng. Enrique R. Noya (Title/Position)
Other senior staff: Fernando Spigatini Norma Acosta
[3] Type of cyclotron: Isochronous, NegativeIon Manufacturer: CTI Model: KDS112
Year: (i) of installation: 1997 not finished (ii) of any major reconstruction:
[4] Particle beams available:
*H *K *He "He Dual Beams
Beam energies/Range 11 (MeV) Typical currents int 50 (uA) Employet ex d (HA)
Hours per week machine is in operation (excluding maintenance): Installation underway
Hour weer spe k employe radionuclidn di e production:
Hours per week machine maintenance:
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
23 ] [5 Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h
[61 Radionuclides planne producee b o dneat e th rn d i future : "C, 13N, 150.V '
[7] Major radiopharmaceuticals produced:
supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, whic oftenw h ho one ?d san
[9] Is medical research/diagnosis carried out on site/off site? On site
If on site, indicate imaging devices available number
*511KeVSPET Yes * Gamma camera Yes * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) Yes
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections No Thick target yields No o N Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
24 AUSTRALIA AUL-1
[1] Institute: Peter MacCallum Cancer Institute Postal Address: 12 Cathedral Place East Melbourne, VIC 3002
Telephone: 61-3-96561852 Fax/E-mail: 61 -3-96561826; rhicks@petermac. unimelb. edu. au
[2] Person-in-charge: RodneyDr. Hicks (Title/Position) Director of Nuclear Medicine & PET
Other senior staff: Peter Eu David Binns
[3] Type of cyclotron: In negotiation - planning & site development in progress Manufacturer: Model:
Year: (i) of installation: 1998 planned majoy an (ii f r)o reconstruction:
[4] Particle beams available:
*H *H "He "He Dud Beams
Beam energies/Range (MeV) Typical currents int (HA) Employet ex d (»iA)
Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway
Hours per week employed in radionuclide production:
Hour weer spe k machine maintenance:
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
25 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
[6] Radionuclides planned to be produced in the near future: "C. 18F, 124I
[7] Major radiopharmaceuticals produced: F-FDG F-Fluoride C-Acetate C-Methionine
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Planned for other3 insitutions
[9] Is medical research/diagnosis carried out on site/off site? Yes, on site
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ?
26 AUSTRALIA AUL-2
[1] Institute: Austin Repatriation& Medical Centre Postal Address: Studley Road Heidelberg, VIC 3084
Telephone: 61-3-94963995 Fax/E-mail: 61-3-945 76605; htd@austin. unimelb. edu. au
[2] Person in-charge: Dr. Henri Tochon-Danguy (Title/Position) Senior Radiochemist
Other senior staff: Marcus Cook John Sachinidis
] [3 Typ cyclotronf eo : Negative Ion Accelerator Manufacturer: IBA Model: Cyclone 10/5
Year: (i) of installation: 1992 (ii) of any major reconstruction: 1996 (new ion-sources)
[4] Particle beams available:
*H "•*: i * , • - . 'VfH 'He «He Dual Beams Beam energies/Range 10 5 (MeV) Typical currents int 50 20 (HA) Employed ext (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance)2 1 :
Hour weer spe k employe radionuclidn di 2 1 e production:
Hours per week machine maintenance: 4
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
27 [5] Radionuclides produced:
Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch
"C "N 32 weekper 6 "C02 or "CH4 li N '°o 4 weekper 4 "NH4OH n I4 o N GBq/min.4 week5per "02 and "CO2 IS p lts H2 O (95) 32 week4per enriched water recovery
[6] Radionuclides planned to be produced in the near future:
[7] Major radiopharmaceuticals produced: I8F-FDG, '*F-FMISO 1!C-SCH 23390, "C-Flumazenil N-Ammonia 15 I5 0-02, 0-CO2, 0-H2O
[8] supplu Doyo y radionuclides/radiopharmaceutical otheo st r institutions? Yes If yes, which ones and how often? !8F-FDG three time per week 18F-FMISO once weeka
[9] medicas I l research/diagnosis carriesite/ofn o t dou f site? On site
siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) 6 * Positron Emission Tomography (PET) 1 engageu yo e nuclean di Ar r. [10reactioa ] n cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sYe sections Thick target yields No Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
28 AUSTRALIA AUL-3
[I] Institute: Australian Nuclear Science Technology& Postal Address: Organization (ANSTO) Radiopharmaceuticals Division, Operations New Illawarra LucasRd, Heights Private Mail Bag 1 Menai, 2234NSW
Telephone: 61-2-9565 7600 Fax/E-mail: 61-2-9565 7676
[2] Person in-charge: C.R. Jamieson (Title/Position) Operations Manager
Other senior staff: Arnott,D. WatersD. P. Barnes, P. Lam
[3] Type of cyclotron: Negative Ion Manufacturer: IBA Model: Cyclone 30
installationf Yearo ) (i : : 1991 majoy an f r(ii o reconstruction) : Commissioning beamw ne o rooms,otw f 1997
[4] Particle beams available:
4 s ' « < , , . : "MoJnr. -,'j' •">'« i^B. *He He Dual Beams Beam energies/Range 15-30 yes (MeV) Typical currentt in s 400/50 (uA) Employed ext 400/50 (uA) solid/PET targets
Hour weer spe k machin operation i s ei n (excluding maintenance): 100 +
Hours per week employed in radionuclide production: 100 +
Hours per week machine maintenance: 8
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others: Investigative work into separation ofCu isotopes from Ga process effluent
29 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C '% 40 (BOB) week3per "N H20>° 20 (EOB) 2 per month "0 H20'° (ppm) 20 (EOB) studies/year6 >«F Hi*O (96%) 65 (EOB) week6per 6/Ga °*Z« (97%) 90 1 per week '"I lAXe 40 1 per week Nordion process zu'Tl (96%)™Tl 70 3 per week
[61 Radionuclides planned to be produced in the near future: "'ln,'03Pd
[7] Major radiopharmaceuticals produced: Vrz~JUiUij /,-,Garr, , 123,I, 201-.77 BulkD , ,radiochemicals I8 !3 5 F-FDG, N-Ammonia, H2' O Radiopharmaceuticals 11CHJ
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Radionuclides as for (7) supplied to Radiopharmaceuticals Division Operations furtherfor processing radiopharmaceuticalto saleand and distribution (one to two weekly batches of each) radiopharmaceutical to Royal Prince Alfred Hospital, Sydney PET facility (5 days per week), and to other local hospitals (I8F-FDG) (one day per week). Expected increase this year to four times per week commercial for 18F-FDG within Sydney
[9] Is medical research/diagnosis carried out on site/off site? Off site
If on site, indicate imaging devices available number
KeVSPE1 51 * T 7 * Gamma camera 2 Singl* e Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 1 engageu yo [10e nuclea]n dAr i a. r reaction cross-section measurements? Yes b. Which type of nuclear data do you use?
Reaction cross sections Yes Thics kYe target yields s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ?
30 BELGIUM BEL-1
[1] Institute: Erasme Hospital Postal Address: Scan/BiomedicalPET Cyclotron Unit Brussels Free University 808 Route de Lennik B-1070 Brussels
Telephone: 32-2-5554711 Fax/E-mail: 32-2-5554701; [email protected]
[2] Person in-charge: Dr. Serge Goldman (Tide/Position)
Other senior staff: Ph. Damhaut; M. Monclus VanJ. Naemen; MulleneersE.
[3] Type of cyclotron: NegativeIon Manufacturer: IBA Model: Cyclone30
Year: (i) of installation: 1990 majoy an f r(ii o reconstruction) :
[4] Particle beams available:
l a , *H *Be «fle Dual Beams
Beam energies/Range 15-30 (MeV) Typical currents int (HA) Employed ext max: 50 (\iA) (HA) 30 (\iA) on target (typically employed)
Hours per week machine is in operation (excluding maintenance): 75
Hours per week employed in radionuclide production: 15
Hours per week machine maintenance: 4
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
31 [5] Radionuclides produced:
Radionnclide Target Activity (GBq) Frequency Comments Produced Material per batch (enrichment)
"C N2 /0,5% O2 2 2 per week IJ N H2O/EtoH) 37 10 per week "NHS producedin li target o H2'°0 6.5 year50per H^O producedin target ISp S H2' O (>95%) 25 week4per enriched water not recovered
[6] Radionuclides planne producee b o dneat e th r n di future :
[7] Major radiopharmaceuticals produced: !8F-FDG, '*F-Altanrain, 6-'SF-Fluoro-L-DOPA 13 + I5 C-Methionine," N-NH4 , O-H2O
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often?
medicas I [9] l research/diagnosi siten O s carriesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . [10ra reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use?
Reaction croso sN sections Thico kN target yields Decay data No
[11] Does your institute accept IAEA research fellows for training/experience? Yes
32 BELGIUM BEL-2
[1] Institute: VRIJE Universiteit Brussel Postal Address: Eenheid Cyclotron Laarbeeklaan 103 B-1090 Brussels
Telephone: 32-2-4774864 Fax/E-mail: 32-2-4 774855; pvdwink@vucy. vub. ac. be
[2] Person in-charge: Prof. A. Hermanne; Prof. P. Van den Winkel (Title/Position)
Other senior staff:
[3] Type of cyclotron: AYR Manufacturer: CGR France Model: 560
Year: (i) of installation: 1983 (ii) of any major reconstruction:
[4] Particle beams available:
! Cidw,H,v§S5'.«*i &$%$£, JjjJ2V"f?IT , "He ''He Dual Beams *, '*'* ^c^'f^r^ 2llt?L ' ^sy^f" ° ! Beam energies/Range 5-42 70-27 20-43 (MeV) Typical currentt in s 300 300 45 (»iA) Employed ext 100 100 15 (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 30
Hours per week employed in radionuclide production: 20
Hour weer spe k machine maintenance: 3
Additional applications of the cyclotron: Photonics
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
33 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "Mz Al 0.4MBq 2 per month "Br As WMBq month1per *"Pb/""Tl "UiTl(97.5%) 3700/370 week1per CEPE electrolysis for 77 recovery
] [6 Radionuclides planne producee b o neade t th rn di future :
[7] Major radiopharmaceuticals produced: NaCl201% 9 7n 7i 28'Mg in 9% NaCl
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? "f * Mg in 9% NaCl (2 times per month) 201 Tl in 9% NaCl (1 per week) 77Br in As-pellets (1 per month) medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site
siten Ifo , indicate imaging devices available number
*511KeVSPET I * Gamma camera 3 * Single Photon Tomography (SPET) 2 * Positron Emission Tomography (PET) 1
[10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Yes Thick target yields Yes o N Decay data
[11] Does your institute accept IAEA research fellow training/experiencer fo s ? Yes
34 BELGIUM BEL-3
[1] Institute: MDS Nordion S.A. Postal Address: Zone Industrielle B-6220 Fleurus
Telephone: 32-10-829211 Fax/E-mail: 32-10-829696
[2] Person in-charge: Dr. Claude Pirarat (Title/Position) Manager, Radiochemical Production
Other senior staff:
] [3 Typ cyclotronf eo : Isochronous Cyclotron If Manufacturer: ISA Model: Cyclone30
Year: (i) of installation: 7992 (n) of any major reconstruction:
] [4 Particle beams available:
*'•"'- *He iHe Dual Beams 1 ^xJ^S^ '^sMiSfffiiSr* SKjSF*| ^ • : ™ •^w^-' u S ^IjlEvlp "J." ^* S \ , , ' - 3 Beam energies/Range 15-30 (MeV) Typical currents mt 400 (uA) Employed ext 400 (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance)0 16 :
Hours per week employed in radionuchde production: 160
8 Hour weer spe k machine maintenance:
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
35 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch U,j '^Xe (>99.9%) 100-250 week4per neededas Mljl «ujl (>97%) 150-300 week5per neededas
] [6 Radionuclides planne producee b o dneat e th r n di future :
[7] Major radiopharmaceuticals produced: 201 Tl, 123I, ™I-MIBG, 123IHippuran-Injectable 67Ga (from bulk produced @ NDS Nordion Vancouver (BC Canada) supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes Bulk 201Tl - Europe, North & South America 1231, 20ITl - Europe (OEM manufacturing) medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Offsite
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sYe sections Thics kYe target yields s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
36 BELGIUM BEL-4
] [1 Institute: Institute of Nuclear Sciences Postal Address: University of Gent Proeftuinstraat86 B-9000 Gent
Telephone: 32-9-2646616 Fax/E-mail: 32-9-2646699; karelstrijckmans@rug. ac. be
[2] Person in-charge: KarelDr. Strijckmans (Title/Position) Research Director
Other senior staff: Patrick Goethals
[3] Type of cyclotron: Isochronous Manufacturer: CGR-MeV (France) Model: 520
installationf Yearo ) (i : : 1977 (ii) of any major reconstruction: 1982
] [4 Particle beams available:
vir *"*'- " r S ^ • ? 'ESjj- 4 ,;•*»•: -?;.- H §.,& ^H f *He He Dual Beams £*£\ * Beam energies/Range 2.5 - 24 14.5- 3 6-32 10-29 nd(14,5)+Be (MeV) Typical currentt in s (HA) Employed ext 20 20 1 1 (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 66
Hours per week employed in radionuclide production: 11-17
Hour weer spe k machine maintenance: 1
Additional applications of the cyclotron: Charged particle and fast neutron activation analysis (CPAA, FNAA) for trace element analysis; Production of customized calibration sources tracersdevelopmentthe and for of chemical preconcentration separationand procedures; Particle induced X-ray emission analysis (PIXE)for trace element analysis; Thin layer activation (TLA)for wear studies, Fast neutron beam dosimetry
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
37 [5] Radionuclides produced:
Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch
"C N2 (not) 60 1-2weekper "0 N2 (not) GBq/min4 1-2 per week on-line >yF Jii H2O (97%) 10 1-2 per week enriched water recovery "Co (not)Fe 0.1 1 per -week a'Rbf'mKr (nat)Kr 0.4 2 per week
[6] Radionuclides planned to be produced in the near future:
[7] Major radiopharmaceuticals produced: !55 15 I5 ' O2, C O2, C O 11 C-TdR, C-methoxyprogabidic acid i8F-Fluoride 55Co2+, 8lRb^lmKr
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes 81 Rb/*lmKr generator, 2 per week
medicas I [9] l research/diagnosi siten O s carriesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurementso N ? b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sYe sections Thics kYe target yields Decay data Yes
[11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ?
38 BELGIUM BEL-5
[1] Institute: U.Z. Gasthuisberg Postal Address: Nuclear Medicine Herestraat 49 B-3000Leuven
Telephone: 32-16-343714 Fax/E-mail: 32-16-343 759; guybormans@ UZ. kuleuven.be ac.
[2] Person in-charge: Prof. Guy Bormans; Prof. L. Mortelmans (Title/Position) Radiopharmacy;PET Head Centre ofPET
Other senior staff: J. Nuyts
[3] Typ cyclotronf eo : Negative Ion Manufacturer: IBA Model: Cyclone 10/5
installationf Yearo ) (i : : 1991 (ii) of any major reconstruction:
[4] Particle beams available:
"Hjs^il .-svr-'-^S. JHe 4He Dual Beams "•*•:d , ; -•« .- ^si.-es Beam energies/Range 10 5 (MeV) Typical currents int 20 10 (HA) Employed ext 20 10 (HA)
Hours per week machine is in operation (excluding maintenance): 15-20
Hours per week employed in radionuclide production: 15-20
Hours per week machine maintenance: 1 daymonthper
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
39 [5] Radionuclides produced:
Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C ""'N 20 5 per week "N na'H^O 1 week3per na "0 'N2 5 2 per week >« S F H2' 0 (97%) 25 10 per week enriched H2 0 recovery
[6] Radionuclides planned to be produced in the near future:
] [7 Major radiopharmaceuticals produced: F-FDG N-Ammonia O-Water C-Acetate
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? I'ft F-FDG otherto centres casein of problems with their F-FDG IK production (~ 30/year)
medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera 4 * Single Photon Tomography (SPET) 5 Positro* n Emission Tomography (PET) 1 (second camera end 1997) engageu yo e nuclean dAr i r. [10 a reactio] n cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
40 BELGIUM BEL-6
[1] Institute: Universite de Liege Postal Address: Centre de Recherches du Cyclotron Sort Tilman B-4000 Liege
Telephone: 32-4-3663687 Fax/E-mail: 32-4-3662946; luxen@pet. crc. ulg. ac. be
[2] Person in-charge: A. Luxen (Title/Position) Director
Other senior staff: C. Brihaye; G. Del Fiore; C. Lemair; A. Plenevaux Aerts;J. Salmon;E. MaquetP.
[3] Typ cyclotronf eo : Manufacturer: CGR MeV Model: 520
Year: (i) of installation: 1972 (ii) of any major reconstruction: Will replacedbe 1998in
[4] Particle beams available: : ' • **H""" ' a-. 4- !, .y ito • ' 'He *fle Dual Beams
Beam energies/Range 6-23 6-10 (MeV) Typical currentt in s (HA) Employet ex d 15 15 (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 45
Hour weer spe k employe radionuclidn di e production: 30
Hour weer spe k machine maintenance: 15
Additional application cyclotrone th f so : PIXE PET radioisotopes production
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
41 [5] Radionuchdes produced:
Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq) per batch "C 2000mCi 4 per week "CHJ n N2 o N2 100mCi week60per H,"0 U !i N H2O 150mCi 2 per week NH4* ISp e JS H2' O (96%) 1500 mCi weekper 6 Enriched H2 0 recovery
[6] Radionuchdes planne producee b o neade t th r n di future '
[7] Major radiopharmaceuticals produced: ISIff F-FDG, ISI SF-DOPA,f IfsfF-Tyrosine, !SIDF-Altansenne C-Methiomne, C-Flumazeml, 13 I5 N-Ammoma, H2 O
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions^ Yes If yes, which ones and how often? 18F-FDG, every mCi, hospital1 120 day,to
[9] Is medical research/diagnosis earned out on site/off site? On site
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph/ y (PET) engageu yo e nuclean di Ar r a reactio[10] n cross-section measurements9 No b Which type of nuclear data do you use?
Reaction cross sYe sections Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience'' Yes
42 BELGIUM BEL-7
[1] Institute: Universite Catholique de Louvain Postal Address: Centre de Recherches du Cyclotron 2, Chemin du Cyclotron B-1348 Louvain-la-Neuve
Telephone: 32-10-472998 Fax/E-mail: 32-10-452183
[2] Person in-charge: Dr. Michel Cogneau (Title/Position)
Other senior staff: G. Ryckewaert M. Loiselet
[3] Type of cyclotron: Isochronous - Negative Ion (H) Manufacturer: IBA Model: Cyclone (Prototype)30
installationf Yearo ) (i : : 1987 (li) of any major reconstruction:
[4] Particle beams available:
IjT "t ,, Dual Beams "• '-S+.X,?* ' • - Ifle :_ 'He
Beam energies/Range 15-30 (MeV) Typical currentt m s 20 - 350 (uA) Employed ext 20 - 250 (uA)
Hours per week machine is in operation (excluding maintenance): 50
Hour weer spe k employe radionuclidn di e production: 50
Hour weer spe k machine maintenance: 4
Additional application cyclotrone th f so : Production of radioactive beams,ion post-accelerated with CYCLONE
Radio therapy/Activation Analysis/Radiobiology/Physics: Physics
Others: Nuclear Physics Nuclearand Astrophysics
43 [5] Radionuchdes produced'
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C na'N 40 2 per week naI "N H2 0 4 3 per week n na o '02 10 x 0.3GBq 2 per week batch >* F H2'*O (96%) 10 4-5 per week enriched H^O recovery st>Y s °Sr CO3 (92%) 1 week1per target recovered
] [6 Radionuchdes planne producee b o neade t th rn di future :
] [7 Major radiopharmaceuticals produced: !8F-FDG I! l! !I C-COC-Accetate,2, CO, C- C-Palmitate,'' "C-Thymidme N-Ammoma 15O-Oxygen,ISO-Water, 'sO-Carbon Monoxide, I5O-Carbon dioxide
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions9 Yes If yes, which ones and how often? 18T-FDG 3 Hospitals occasionally Hospitals2 weekly
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site? Yes
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean di Ar r. reactioa [10] n cross-section measurements? Yes b Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Yes Thics Ye k target yields Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
44 BELGIUM BEL-8
] [1 Institute: Universite Catholique Louvainde Postal Address: Centre de Recherches du Cyclotron Chemin2, Cyclotrondu B-1348 Louvain-la-Neuve
Telephone: 32-10-472998 Fax/E-mail: 32-10-452183
[2] Person in-charge: RyckewaertIr.G. (Title/Position) Director
Other senior staff: M. Loiselet Michel Cogneau
[3] Typ cyclotronf eo : Isochronous Multiparticle Variable Energy Manufacturer: ThomsonCSF - Model: Cyclone
installationf Yearo ) (i : : 1969-1972 (ii) of any major reconstruction:
[4] Particle beams available:
! ;! s-p8ffS*±r"S;Sr:^ ;S';' F?l^J7 ':;3ft ^™«^^E^S^5iipL^;.*.v;,>,;:;i;K ..,: ;lHe~:v Dual Beams •£&i-]--%&£S*i.i3J§ IPlpisy^^ii;*; '• :.'^iiyy;;-:< Beam energies/Range 20-85 10-55 15145 - 20-110 (MeV) Typical currentt in s 30 20 5 20 (HA) Employed ext 20 JO 5 10 (HA)
Hours per week machine is in operation (excluding maintenance): 150 av.
Hour weer spe k employe radionuclidn di e production: av.8
Hour weer spe k machine maintenance: av. 4
Additional applications of the cyclotron: Nuclear Physics and Astrophysics, Neutron Therapy, Applied Physics
Radiotherapy/Activation Analysis/Radiobiology/Physics: Radiotherapy, Physics
Others: Nuclear Physics and Nuclear Astrophysics
45 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "MX Al(l 00%) 20MBq month1per "Fe Mn (100%) 0,2-2 week1per V4 VJ V6~, 1C Mo (not) 0,1-0,01 1 per month
[6] Radionuchdes planne producee b o dneae t th r n di future : 85Sr
[7] Major radiopharmaceuticals produced: 52Fed, supplu yo o y D radionuchdes/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? Sporadically - To 2 Centres
[9] Is medical research/diagnosis earned out on site/off site? Yes
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomograph1 y (PET) engageu yo e nuclean dAr i . r[10a reactio] n cross-section measurementss Ye ? b. Which type of nuclear data do you use?
Reaction cross sections Yes Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
46 BRAZIL BRA-1
[1] Institute: Institute de Engenharia Nuclear Postal Address: Caixa Postal 68550, 2, Chemin du Cyclotron Rio de Janeiro
Telephone: 55-21-5604113 ext. 2184 Fax/E-mail: 55-21-5902692
[2] Person in-charge: Sergio Chaves Cabral (Title/Position) Head of Physics Department
Other senior staff: MariaAna Silveira Braghirolli; Jackson QueirozL. de Britto; Miguel Angela Valle Bastos; Luiz Claudio Martins Aleixo
[3] Typ cyclotronf eo : Multiparticle, Variable Energy, Isochronous Manufacturer: The Cyclotron Corporation Model: CV-28
Year: (i) of installation: 1974 (ii) of any major reconstruction: 1985
[4] Particle beams available:
** -•V~! 1H JHe ~ tHe Dual Beams • .3*^.". rv2 ; ,.--:"; «: •> • . ', *Hf" > S fV Beam energies/Range 2-24 4-14 36 6- 8-28 (MeV) Typical currents int (uA) Employet ex d 20-30 20-40 2-10 3-40 (UA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 24 hours*/40 hours**
Hours per week employed in radionuclide production: 8 hours/30 hours**
Hours per week machine maintenance: 8
Additional application cyclotrone th f so : Nuclear data measurements, Charge particle activation analysis, Studies of radiation damage materialsin
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others: productionThe * stoppedwas October 1995, rebuildto every ancillary system (air conditioning and ventilation system, filters, power supplies etc.) ** The production will start October 1997. thisAt time productionthe of 12willI target. Xe production4 The via be will week startper in withGBq 7 3 1997 increasing to 165 GBq per week in 2000.
47 ] [5 Radionuchdes produced
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h *Mj* U4Te (96%) 755 1 per week
] [6 Radionuchdes plannehdes planned producee b neao de t th rn di futur e >23'23IviaIvia' 24I24Xe(37GBqAXe (37 GBq/week)** 18is>8 18 la ' ' F-FDG H2 via GBq/week)** O(37 68 GBq/week)**Znvia (12 6^Ga
[7] Major radiopharmaceuticals produced
supplu yo o y D radionuchdes/radiopharmaceutical ] [8 otheo st r institutions9 Yes If yes, which ones and how often9 Once a week to 3 hospitals in Rio de Janeiro
medicas I [9] l research/diagnosis carriesite/ofn o t dou f site9 Offsite
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a Are you engaged in nuclear reaction cross-section measurements9 Yes b Which type of nuclear data do you use9
Reaction cross sYe sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience9 Yes
48 BRAZIL BRA-2
[I] Institute: Institute Pesquisasde Energeticas Nuclearese Postal Address: Caixa Postal 11049 Pinheiros, CEP 05422-970 Sao Paulo
Telephone: 55-11-8169000 55-11-8169275 Fax/E-mail: 55-11-2123546 55-11-8169186
[2] Person in-charge: Wanderley Limade (Title/Position) Head, Industrial Applications Department Person in-charge: C. Pagano Goncalves Silvada (Title/Position) Head, Radioisotope Department
Other senior staff: Sumair Gouveia de Araujo; Valdir Sciani Lucia Ana PinheiroV. Lima; HouiWo Ling Wang; Margarida Enoshita Otomo; Jair Mengatti; Jodo Alberto Osso Jr.
[3] Typ cyclotronf eo : Isochronous, Compact, variable Energy Manufacturer: The cyclotron corporation Model: CV-28
installationf Yearo ) (i : : 1981 majoy an (ii f r) o reconstruction :
[4] Particle beams available:
'H *a *He
Hours per week machine is in operation (excluding maintenance): 10
Hour weer spe k employe radionucliddn i e production: 8
Hours per week machine maintenance: 5
Additional application cyclotrone th f so : Research calibrationon sources, Excitation Junctions Activation Analysis, Nuclear Reactions
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
49 [5] Radionuclides produced:
Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq) per batch >* F H2'*O (96%) tracer not routinely optimization for routine production "Co na'Ni Metal 230 not routinely '"In aa'Cd electroplated. tracer optimization routinefor production 124™ ,~. '"I TeO2 3700 1-2 per week reirradiated
[61 Radionuclides planned to be produced in the near future: !8F, "'In
[7] Major radiopharmaceuticals produced: 18F-FDG (planned)
supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? Hospitals medicaland centres: once weeka
medicas I ] l[9 research/diagnosio N s carriesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomograph1 y (PET) engageu yo e nuclean dAr i r. [10a reactio] n cross-section measurements? b. Which type of nuclear data do you use?
Reaction cross sections Yes Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
50 BRAZIL BRA-3
[1] Institute: Institute de Pesquisas Energeticas e Nucleares Postal Address: Travessa400 R. Cidade Universitdria 05508-900 Sao Paulo
Telephone: 55-11-8169275 55-11-8169000 Fax/E-mail: 55-11-8169186 55-11-2123546
[2] Person in-charge: Wanderley de Lima (Title/Position) Head, Industrial Applications Department Person in-charge: C. Pagano Convolves da Silva (Title/Position) Head, Radioisotope Department
Other senior staff: Sumair Gouveia Araujo;de Valdir Sciani Ana Lucia V. Pinheiro Lima; Wo Houi Ling Wang; Margarida Enoshita Otomo; Jair Mengatti; Joao Alberto OssoJr.
] [3 Typ cyclotronf eo : Fixed field, Fixed frequency Manufacturer: IBA Model: Cyclone-30
installationf Yearo ) (i : : 1998 (ii) of any major reconstruction:
[4] Particle beams available:
*$&j& ^.gajjM-fa! " ' ipc Baal Beams ' ^ «-£§$% * » * *• *'* Beam energies/Range 15-30 (MeV) Typical currentt in s up to 350 (uA) Employed ext ± up to 350 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): Planned40
Hour weer spe k employe radionuclidn di e production: 30
Hour weer spe k machine maintenance: 8
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
51 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
[61 Radionuchdes planned to be produced in the near future: <8F,123I, 67Ga,"!In,201Tl
[7] Major radiopharmaceuticals produced.
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often?
[9] Is medical research/diagnosis earned out on site/off site9 No
siten o f ,I indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? b Which type of nuclear data do you use 7 Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
52 CANADA CAN-1
[1] Institute: TRIUMF Postal Address: 4004 WesbrookMall Vancouver, BC Canada V6T 2A3
Telephone: 1-604-2221047 Fax/E-mail: 1-604-2221074
[2] Person in-charge: Dr. Nigel StevensonR. (Title/Position)
Other senior staff: R. Van Den Elzen
[3] Type of cyclotron: ff /Sector-focused Manufacturer: The Cyclotron Corporation Model: CP42
Year: (i) of installation: 1980 may reconstructionr an jo f (iio ) : 1991
] [4 Particle beams available:
*fl j -- ffc*-\ iHe "He Dual Beams , J""si Beam energies/Range 15-42 (MeV) Typical currents int 250 (HA) Employet ex d 250 (uA)
Hours per week machine is in operation (excluding maintenance): 756
Hours per week employed in radionuclide production: 756
Hours per week machine maintenance: 12
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
53 ] [5 Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
"N H2O 4 per week for PET '*F na'Ne 4 per week for PET "Co "Ni 0/Ga oaZn 5 per week "'In luCd 6 per week !2il u*Xe MlTl -""77 week3per
[6] Radionuchdes planned to be produced m the near future:
[7] Major radiopharmaceuticals produced: 123I Based Radiopharmaceuticals
supplu yo o y D radionuchdes/radiopharmaceutical ] [8 otheo t s s r institutionsYe 9 If yes, whic oftenw h ho one ?d san TRIUMFproduces radionuclides NordwnMDS for MDS Nordion supplieris radiochemicalsofthe
medicas I [9] l research/diagnosis earne site/ofn o t dou f site?
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a Are you engaged m nuclear reaction cross-section measurements? No b Which type of nuclear data do you use 9 Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience?
54 CANADA CAN-2
[1] Institute: TRIUMF Postal Address: 4004 WesbrookMall Vancouver,BC Canada V6T2A3
Telephone: 1-604-2221047 Fax/E-mail: 1-604-2221074
[2] Person in-charge: Dr. Nigel R. Stevenson (Title/Position)
Other senior staff: R. Van Den Elzen
[3] Type of cyclotron: K /Sector-focused Manufacturer: EBCO Model: TR30
Year: (i) of installation: 1990 (ii) of any major reconstruction: 1995
[4] Particle beams available:
*H *H 'He 'He Dual Beams
Beam energies/Range 75-50 yes (MeV) Typical currentt in s 2x350 (uA) Employet ex d 2x350 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 156
Hours per week employed in radionuclide production: 156
Hours per week machine maintenance: 12
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
55 ] [5 Radionuclides produced
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Co "Ni 0/Ga MZn '"In luCd '•SI u*Xe MITl *"Tl
[6] Radionuclides planned to be produced in the near future
[7] Major radiopharmaceuticals produced 123 BasedI Radiopharmaceuticals
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions7 Yes If yes, which ones and how often"? TRIUMF supplies NordionMDS with irradiated target materials MDS Nordion is supplier of radiochemicals
medicas I ] l[9 research/diagnosio N s earnesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engagedu yo e nuclean Ar i r a reactio[10] n cross-section measurementso N 9 b Which typ nucleaf eo useu r datyo 7 o ad
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience9
56 CANADA CAN-3
[1] Institute: TRIUMF Postal Address: 4004 WesbrookMall Vancouver, BC Canada V6T2A3
Telephone: 1-604-2221047 Fax/E-mail: 1-604-2221074
[2] Person in-charge: Nigel Dr. StevensonR. (Title/Position) (for radionuclideproduction MeV)470 at
Other senior staff: ElzenDen Van R.
[3] Typ cyclotronf eo : ff /Sector-focused MeV 520 Manufacturer: TRIUMF Model:
installationf Yearo ) (i : : 1962 (ii) of any major reconstruction: 1997
[4] Particle beams available:
'H *R "He "He Dual Beams
Beam energies/Range 70520 - (MeV) Typical currentt in s 150 (HA) Employet ex d 140 nA@ (HA) 470 MeV
Hour r weespe k machin operation i s ei n (excluding maintenance)0 13 :
Hours per week employed in radionuclide production: ~I20
Hours per week machine maintenance: 24
Additional applications of the cyclotron: Scientific Research
Radiotherapy/Activation Analysis/Radiobiology/Physics: Proton Therapy
Others:
57 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Sr/"Rb na'Mo 2-4 per month MeV 470 «-Sr^Rb na'Rb monthper 2-4 70MeV
[6] Radionuchdes planned to be produced in the near future: ZnO targets to produce 67Cu at 470 MeV
] [7 Major radiopharmaceuticals produced:
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Srr Rb to MDS Nordion. MDS Nordion is supplier of radiochemicals
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engagedu yo e nuclean Ar i r. a [10reactio] n cross-section measurementss Ye ? b. Which type of nuclear data do you use?
Reaction cross sYe sections Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience?
58 CANADA CAN-4
] [1 Institute: TRIUMF PET Programme Postal Address: 4004 Wesbrook Mall Vancouver,BC Canada V6T2A3
Telephone: 1-604-2221047 Fax/E-mail: 1-604-2221074
] [2 Person in-charge: Mr. Ken Buckley, Project Engineer (Title/Position)
Other senior staff: Tom Ruth
] [3 Typ cyclotronf eo : Negative Ion, Sector-focused Manufacturer: EBCO Model: TR13
Year: (i) of installation: 1994 majoy an f (iir o reconstruction) :
] [4 Particle beams available:
'H 2H "He *He Dual Beams
Beam energies/Range 13-19 yes (MeV) Typical currentt in s 100 circulating,uA (uA) 50 (uA) per side extracted Employed ext 20-30 typicallyuA (HA) used targeton
Hours per week machine is in operation (excluding maintenance): 35
Hour weer spe k employe radionuclidn di e production: 75
Hour weer spe k machine maintenance: 2.5
Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
59 [5] Radionuclides produced:
Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 'Be 'Li 37MBq 1 per week "C N2 + 10%H7 20 10 per week as "C-CH4 >* S F (>90%)H^O 5 1 per week enriched H2' O recovered >
[6] Radionuclides planne producee b neao de t th r n dfuturei :
] [7 Major radiopharmaceuticals produced: I8F-FDG, '*F-DOPA, C-Safoperse, C-Raclopride, C-Tetrabenazine, C-Methylphenidate, "C-Schering 23390, "C-6-FMT
supplu yo o y D radionuclides/radiopharmaceutical[8] otheo t s r institutions? Yes If yes, whic oftenw h ho one ?d san is F-FDGweekper 1
[9] Is medical research/diagnosis carried out on site/off site? On site On campus 2.5 km from cyclotron
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Yes Thics kYe target yields s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
60 CANADA CAN-5
[I] Institute: McMaster University Postal Address: Radiology and Nuclear Medicine 1200 Main St. West, Hamilton, ON Canada L8N3Z5
Telephone: 1-905-5212100 ext. 5671 Fax/E-mail: 1-905-5461125
[2] Person in-charge: Prof. Gunter Firnau (Title/Position) Radiochemist
Other senior staff: Roman Chirakal Jia Juen Chen
[3] Type of cyclotron: RDS-112 Manufacturer: CTI Model:
Year: (i) of installation: 1990 a18, (ii) of any major reconstruction: Implementation of' F-F2 Target
[4] Particle beams available:
*H ^ JHe "He Dual Beams
Beam energies/Range ;; (MeV) Typical currentt in s (uA) Employet ex d 40 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 6
Hour weer spe k employe radionuclidn di e production: 6
Hour weer spe k machine maintenance: 2
Additional applications of the cyclotron: Production of positron emitting radionuclides supportto 3 PET-scanners for clinical PET and clinical research; and development of novel radiopharmaceuticalsPET for
Radiotherapy/Activation Analysis/Radiobiology/Physics:
61 [5] Radionuchdes produced'
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch l "CC02 *N2+l%O2 55 week3per for organic. Synthesis IJ + NNH4 H2"0 75 week5per for heart sudies used Has 2 '*Oin 15 !5 0 02 N2+2 5% O2 5 week6per brain activation studies "r a S H2' O (96%) 22 weekper 7 enriched H2 O recovery 19 ls /tf^ FF2 O-gas (98%) 13 2 per week U2-gas is recovered
[61 Radionuchdes planned to be produced in the near future: 94mTc, W3Pd
[7] Major radiopharmaceuticals produced: F-Fluoromisoimidazol, F-FDG, F-Fluorodopamine6- 6- F-Fluoro-L-DOPA, 6- F-Fluoro-L-meta-tyrosme, F-Fluoroprophyl-spiperome N-Ammonia C-S-20098, "C-Acetate 'O- Water
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san i p Ottawatransportto FDG car of by mCi 30 ± week 2per 300
[9] Is medical research/diagnosis earned out on site/off site? On site If on site, indicate imaging devices available number
*511KeVSPET Gamm* a camera 3 * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2 engageu yo e nucleaAr n di ra reactio[10] n cross-section measurements? No b Which type of nuclear data do you use?
Reaction cross sYe sections Thics kYe target yields Decay data Yes
[11] Does your institute accept IAEA research fellow training/experiencer sfo 9 Yes
62 CANADA CAN-6
[1] Institute: Clarke Institute of Psychiatry Postal Address: College250 Street Toronto,ON Canada M5T1R8
Telephone: 1-416-9794651 Fax/E-mail: 1-416-9794656
[2] Person in-charge: SylvainDr. Houle (Title/Position) Head, CentrePET
Other senior staff: Alan Wilson;A. Jean SilvaDa
[3] Type of cyclotron: Fixed Energy Isochronous Manufacturer: Scanditronix Model: MC-17
Year: (i) of installation: 7997 (ii) of any major reconstruction:
[4] Particle beams available:
'H ZH JHe "He Dual Beams
Beam energies/Range 17 5.5 (MeV) Typical currentt in s 15-60 20-25 (uA) Employet ex d 10-40 10-12 (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance)5 2 - 0 2 :
Hours per week employed in radionuclide production: 20 - 22
3 2- Hour weer spe k machine maintenance: additional one week maintenance per year
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics: Others:
63 ] [5 Radionuchdes produced:
Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C I4N 40 5 per week n o <4N n/a week10per on line production* >«F S H2' 0 (50-97%) 4 4 per week enriched water recovery lineOn continuous* production activationfor studies
] [6 Radionuchdes planne producee b o dneae t th rd m future :
] [7 Major radiopharmaceuticals produced: !5O-Water, !8F-FDG, '8F-Setoperone "C-Raclopride, "C-SCH23390, "C-RTI32
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No If yes, which ones and how often7
[9] Is medical research/diagnosis carried out on site/off site?
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience?
64 CANADA CAN-7
[1] Institute: Montreal Neurological Institute Postal Address: McGill University 3801 University Street Montreal, Quebec Canada H3A2BA
Telephone: 1-514-3988526 Fax/E-mail: mirko@pet. mni.mcgill.ca
] [2 Person in-charge: Prof. Mirko Diksic (Title/Position)
Other senior staff: Dean Jolly
[3] Typ cyclotronf eo : NegativeIon Manufacturer: IBA Model: Cyclone 18/9
installationf Yearo ) (i : : 1993 (ii) of any major reconstruction:
] [4 Particle beams available:
'H *H 'He 'He Dual Beams
Beam energies/Range 18 9 yes (MeV) Typical currentt in s 100 60 (HA) Employed ext 30-40 20 (HA)
Hours per week machine is in operation (excluding maintenance): 20-30
Hours per week employed in radionuclide production: 20-30
Hours per week machine maintenance: 2-3
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
65 [5] Radionuchdes produced
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "CO, 22 10 per week n "N2 o '% 07-2 week40per 18 £• H,'aO (96%) 7 2-3 per week '*FF, "Ne 11 2-3 per week
] [6 Radionuchdes planne producee b o dneae t th rn d i future .
[7] Major radiopharmaceuticals produced: I8F-FDG, lSF-DOPA, "C-RO 15-1788, "C-Deprenyl, "C-a -methyl-L-trypotophan, "C-PK-11195, 11C Bensotropme supplu yo o y D radionuchdes/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often"?
[9] Is medical research/diagnosis earned out on site/off site9 On site siten o f ,I indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2
engageu yo e nuclean dAr i [10 r a reactio] n cross-section measurements'7 No b Which type of nuclear data do you use9
Reaction cross sYe sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience9 Yes
66 CHINA CPR-1
[1] Institute: China Institute of Atomic Energy Postal Address: (99)275 P.O. Box 102413 Beijing
Telephone: 86-01-69358090 Fax/E-mail: 86-01-69357195
[2] Person in-charge: Li Da Kang (Title/Position)
Other senior staff: Zhao Zhi;Gui Zhao Zhen Shen Heng;Lu; de XiangXie He; Gian XuShu
] [3 Typ cyclotronf eo : NegativeIon Manufacturer: IBA Model: Cyclone30
installationf Yearo ) (i : : 1995 majoy an (iif ro ) reconstruction:
[4] Particle beams available:
. "V^gj. ^ _;,•«4, • *He,io • "Safe Dual Beams v_ % Beam energies/Range 15-30 (MeV) Typical currentt in s (uA) Employet ex d 100 ~ 220 GtA)
Hours per week machine is in operation (excluding maintenance): 4 days per week
Hours per week employed in radionuclide production: days 4 weekper
Hours per week machine maintenance: day1 weekper
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
67 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 18p HfO (96%) 14.8 2 per week as'sFDG >'Co ^Ni (>99%) 37 1 per week enrichedNi recovery 6/Ga HOI'7Zn 15 1 per week MGe "°'Ga Alloy 1.85 few '"In cd nat cdor j 11 / j 15 week1per (>96%) ->UITI natrpi 3 1 per week
[6] Radionuchdes planned to be produced in the near future: I23I, >S6Re
[7] Major radiopharmaceuticals produced: 67Ga,Tl, 201 IS'F-FDG
[8] Do you supply radionuchdes/radiopharmaceuticals otheo t s r institutionsYe ? If yes, which ones and how often? monthper 1 57USA Co to
[9] Is medical research/diagnosis earned out on site/off site? Off site On campus 2 5 km from cyclotron
siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2
[10] Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections Yes Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellow training/experience'r fo s ' Yes
68 CHINA CPR-2
[1] Institute: Beijing Normal University Postal Address: Beijing Cyclotron Produced Radiopharmaceutical Laboratory Institute of Applied Chemistry 100875 Beijing
Telephone: 86-01-62207786, 62208396 Fax/E-mail: 86-01-62200567; [email protected]
[2] Person in-charge: Liu Li Bo (Title/Position) Professor ofRadiochemistry, Dean
Other senior staff: Huang ZhengXing; Prof. Liu Zheng Hao; Zhang Hui Xing; Chen Ru Yi; Tang Zhi Gang
] [3 Typ cyclotronf eo : Positive Ion Manufacturer: TCC Model: CS-30
Year: (i) of installation: 1986 majoy an f (iiro )reconstruction :
[4] Particle beams available:
'H *H 'He "He Dual Beams
Beam energies/Range 26 12 30 24 (MeV) Typical currents int 250 (uA) Employed ext 100 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance)5 2 :
Hour weer spe k employe radionuclidn di 0 2 e production:
Hours per week machine maintenance: 4
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
69 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Co natZn 8 1 per week 0/Ga nat Zn 74 1 per week '"In natCd 3 7 week1per
] [6 Radionuchdes planne producee b o dneat e th r n di future :
] [7 Major radiopharmaceuticals produced: Ga-Citrate inIn-Chloride
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? If yes, whic oftenw h ho one ?d san 57Co Instituteto of Atomic Energy Beijingin 67 Ga Hospitalsto Beijingin
[9] Is medical research/diagnosis earned out on site/off site? No
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Yes Thics kYe target yields s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience? No
70 CHINA CPR-3
[1] Institute: Beijing Normal University Postal Address: Beijing Cyclotron Produced Radiopharmaceutical Laboratory Institute of Applied Chemistry 100875 Beijing
Telephone: 86-01-62207786, 62208396 Fax/E-mail: 86-01-62200567; [email protected]
[2] Person in-charge: Liu Li Bo (Title/Position) Professor ofRadiochemistry, Dean
Other senior staff: Huang Zheng Xing; Prof. ZhengLiu Hao; Zhang Hui Xing; Chen Ru Yi; Tang Zhi Gang
[3] Typ cyclotronf eo : Positive Ion Manufacturer: TCC Model: CS-22
Year: (i) of installation: 1997 (ii) of any major reconstruction: Donated by UCLA
[4] Particle beams available:
4 'H *EL "He He Dual Beams
Beam energies/Range 22 (MeV) Typical currentt in s 100 (uA) Employet ex d 50 (uA)
Hours per week machine is in operation (excluding maintenance):
Hours per week employed in radionuclide production:
Hours per week machine maintenance:
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
71 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
] [6 Radionuchdes planne producee b neao de t th rn di future : I!C, 13N,15 0,V '
[7] Major radiopharmaceuticals produced:
supplu yo o y D radionuchdes/radiopharmaceutical[8] otheo st r institutions? No If yes, whic oftenw h ho one ?d san
medicas I ] l[9 research/diagnosis earnesite/ofn o t dou f site?
siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b Which type of nuclear data do you use?
Reaction cross sYe sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo o N ?
72 CHINA CPR-4
[1] Institute: Zibo Wanjie Hospital Postal Address: Boshan, Zibo Shandong
Telephone: 86-533-4650000 8730 Fax/E-mail: 86-533-4650830
[2] Person in-charge: Sun Qiyin (Title/Position)
Other senior staff: Wang Ming Fang; Zhao Jun; Wang Chongqing; Li Jiamin; Song Shuqiang
[3] Typ cyclotronf eo : NegativeIon Manufacturer: GE Model: PETTRACE
Year: (i) of installation: 1995 (ii) of any major reconstruction:
[4] Particle beams available:
*H *H ^He 4He Dual Beams
Beam energies/Range 16.5 (MeV) Typical currentt in s (UA) Employed ext 20-30 (UA)
Hour weer spe k machin operation i s ei n (excluding maintenance)6 :
Hours per week employed in radionuclide production: 5
Hours per week machine maintenance: 7
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
73 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 6 "N H2' 0 3 7-5.5 weekper 6 Iyp S H2' O (98%) 75 4 per week enriched !S H2 0 recovery
[6] Radionuchdes planned to be produced m the near future: 11C, 150, S2Rb
[7] Major radiopharmaceuticals produced: F-FDG N-Ammoma supplu yo o y D radionuchdes/radiopharmaceutical[8] otheo st r institutions? No yesf I , whic oftenw h ho one ?d san
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site? Off site
If on site, indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 7
[10] a. Are you engaged m nuclear reaction cross-section measurements7 Yes b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sYe sections Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
74 CHINA CPR-5
[1] Institute: Shanghai Institute of Nuclear Research Postal Address: P.O. Box 800-204 201800 Shanghai
Telephone: 86-21-59553634 Fax/E-mail: 86-21-59552509; [email protected]
[2] Person in-charge: Prof. Wang Yongxian (Title/Position) Director
Other senior staff: Fang Fasheng; Li Jiamin; Song Shuqiang
[3] Type of cyclotron: NegativeIon Manufacturer: IBA Model: Cyclone 30
Year: (i) of installation: 1996 majoy an (ii f r) o reconstruction:
[4] Particle beams available:
1H 4H 3He "He Dual Beams
Beam energies/Range 15-30 (MeV) Typical currentt in s >2mA (uA) Employed ext 400 (HA)
Hours per week machine is in operation (excluding maintenance): 60
Hours per week employed in radionuclide production: 60
Hours per week machine maintenance: 24
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others: Neutron therapy
75 [5] Radionuchdes produced
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 0/Ga Zn (natural) 31 week2per U u Sj *Te (92%) 21 2 per week enriched ~ Te recovery -'"'77 77 (natural) 13 2 per week
[61 Radionuchdes planne producee b o dt neae th rn d i future - II1In,T 57Co,^ 109^,Cd, 68^,Ge
[7] Major radiopharmaceuticals produced 67 Ga-citrate injection 201 77- chloride injection ''^I-Sodium iodide injection
[8] supplu Doyo y radionuchdes/radiopharmaceutical otheo st r institutions? Yes If yes, which ones and how often? To hospitals Shanghaiin vicinity,its weekper and 2
[9] Is medical research/diagnosis earned out on site/off site? Off site
siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i [10r a reactio] n cross-section measurements7 No b Which type of nuclear data do you use?
Reaction cross sections Yes Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experience'r fo s 7 Yes
76 CZECH REPUBLIC CZR-1
[1] Institute: Nuclear Physics Institute Postal Address: Rez near Prague 25068z Re
Telephone: 420-2-66173613 Fax/E-mail: 420-2-6857003; [email protected]
[2] Person in-charge: Ing. Jan §tursa (Title/Position) Head Cyclotron ofthe Division
Other senior staff:
] [3 Typ cyclotronf eo : Isochronous Cyclotron Manufacturer: JINR Dubna, Russia Model: U-120M
Year: (i) of installation: 1977 First beam (n) of any major reconstruction: 1992 Axial injection
[4] Particle beams available:
ri&fe .'4 Dual Beams
^\ -fS-jjft. ££**•"£** r - * * # *• , ^ ^""- T? Beam energies/Range 13-37 12-20 23-54 24-40 (MeV) Typical currentt m s 20 H 90 40 40 (uA) + H 90 Employet ex d 5 5 5 5 (uA) 20
Hour weer spe k machin operation i s ei n (excluding maintenance): 22
Hour weer spe k employe radionuclidn di e production: 14
Hours per week machine maintenance: 8
Additional application cyclotrone th f so : Nuclear Spectroscopy Nuclear Reactions Radiobiology Solid State Physics
Radiotherapy/Activation Analysis/Radiobiology/Physics:
77 [5] Radionuchdes produced'
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 0/Ga MZn (99%) 9 1 per week '"In luCd(98%) 9 1 per month MITl MiTl (98%) 8 1 per week
[6] Radionuchdes planne producee b o neade t th rn di future : 1 Of-r" generator K 8 1 KT-i bl- r 81 m-rr ,
[7] Major radiopharmaceuticals produced:
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Nuclear Research Institute pic,z Re Czech Republic irradiated targets for production 67 Ga 1 per week r weekpe 201 1 77 111In 1 per month (not regularly) medicas I [9] l research/diagnosis earnesite/ofn o t dou f site? Off site
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use?
Reaction croso sN sections Thick target yields No o N Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo o N ?
78 DENMARK DEN-1
[1] Institute: CentrePET Postal Address: Arhus University Hospital Norrebrogade44 VK-8000 Arhus
Telephone: 45-89-493033 Fax/E-mail: 45-89-493020; [email protected]
[2] Person in-charge: Prof. Albert Gjedde (Title/Position)
Other senior staff: Antony Gee, Soren Hansen
[3 ] Typ cyclotronf eo : Negative Ion, Self shielding Manufacturer: GE Model: PETTrace
installationf Yearo ) (i : : 1993 majoy an f r(iio reconstruction) :
[4] Particle beams available:
..-, .$H£,'-r3| • iHe ^He Dual Beams ; *? '- : ": "'H •** Beam energies/Range 16.5 8.4 yes (MeV) Typical currentt in s (HA) Employet ex d 40 40 40 (HA)
Hours per week machine is in operation (excluding maintenance): 55
Hour weer spe k employe radionuclidn di e production: 20
Hours per week machine maintenance: 5
Additional application cyclotrone th f so : Short-lived radionuclides 13N,"C, 15 O, ISFfor production tracers ofPET
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
79 ] [5 Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch l4 "C N2+100ppmO2 >85 10 per week "N week10per n H2'°0 >18 o "N2 >74 20 per week ISp S H2' O (20-95%) >59 3 per week enriched water recovery lil r- FJ 2% (0 + Ne >13 1 per week
[6] Radionuchdes planned to be produced m the near future.
[7] Major radiopharmaceuticals produced: I8F-DOPA, ™F-FDG, !8F,! *F-fi-Fluorophenylalamne, I5O-Butanol C-Methamphetamme, C-Venlafaxme, C-Raclopnde, C-Methiomne, C-NS2214 many other traces
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions7 No If yes, whic oftenw h ho one 9d san
[9] Is medical research/diagnosis earned out on site/off site9 On site
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph7 y (PET)
[10] a Are you engaged m nuclear reaction cross-section measurements9 No b Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience9 Yes
80 DENMARK DEN-2
] [1 Institute: University Hospital of Copenhagen Postal Address: Cyclotron Unit, 3982PET KF and Blegdamsvej 9 DK-2100 Copenhagen
Telephone: 45-35-453896 Fax/E-mail: 45-35-453898; [email protected] rh.
[2] Person in-charge: Mikael Jensen (Title/Position) Physicist in Chief
Other senior staff: Peter Larsen
] [3 Typ cyclotronf eo : Negative Ion, Sector-focused Manufacturer: Scanditronix Model: 32-NIMC
installationf Yearo ) (i : : 1992 majoy an f (iir o reconstruction) :
[4] Particle beams available:
4 to r |£:'• ** "He He Dual Beams Beam energies/Range 16-33 8-16 16-32 yes (MeV) Typical currentt in s 80 (uA) Employet ex d 1-100 1-00 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 30
Hour weer spe k employe radionuclidn di e production: 30
Hour weer spe k machine maintenance: 2
Additional application cyclotrone th f so : Testing of radiation resistance of space programme components variousfor sattelites
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
81 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N-> 80 1-2 per week 1 "N H2' 0 4 5-10 per week na "0 'N2 on-lineGBq 1-2 1-2 per week s'Rb na'Kr 5-10 3 per week """Cd '™Pd 400 MBq 2 per month
] [6 Radionuchdes planne producee b o dneat e th r dm future : 10C
[7] Major radiopharmaceuticals produced: generatorsKr m - ventilationsRb for scintigraphy !8F-FDG i tj F-Dihydrotestosterone N-Ammoma lsO-Water, 15O-Oxygen, !5C-Carbon monoxide
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No yesf I , whic oftenw h ho one ?d san Hospitals and research institutions in the major Copenhagen area
[9] Is medical research/diagnosis earned out on site/off site? Medical research is carried out both on site and off site
siten o f ,I indicate imaging devices available number
KeVSPE1 *51 T Gamm* a camera Yes * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r dat?yo o ad
Reaction cross sections Yes Thics kYe target yields s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
82 EGYPT EGY-1
] [1 Institute: Nuclear Research Centre Postal Address: Atomic Energy Authority Postal Code 13759 Cairo
Telephone: 202-4690840 Fax/E-mail:
] [2 Person in-charge: Prof. M.N.H. Comsan (Title/Position) Chairman
Other senior staff: Z.A. Saleh; M.S. Adbel-Azim; M.A. Aly; A.H. Azzam; M.A. Moustafa
[3] Type of cyclotron: AVF Manufacturer: NIIEFA Model: MGC-20
Year: (i) of installation: 1997 majoy an f r o reconstruction(li) :
] [4 Particle beams available: 5 J****gfl^;\ s lL", V '- ^He.:V' "He Dual Beams • ". s "Pirtsfl^jl . "jgjSV-" P%:" , - Beam energies/Range 5-18 3-10 8-24 6-20 (MeV) Typical currentt m s 200 200 50 50 (uA) Employed ext 50 50 25 25 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): The machine underis installation
Hours per week employed in radionuclide production:
Hours per week machine maintenance:
Additional application cyclotrone th f so : Fast Neutron Research Materials Analysis Nuclear Analytical Techniques
Radiotherapy/Activation Analysis/Radiobiology/Physics: Nuclear Data Bank
Others:
83 [5] Radionuchdes produced (asplanned)
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 0/Ga 0/Zn (95%) weekper 2 '"In '"Cd(95%) 1 per week Ui '"I TeO2 (95%) 3 per week
[6] Radionuchdes planned to be produced m the near future
] [7 Major radiopharmaceuticals produced 67Ga - Gallium Citrate In - Indium Chloride 123 SodiumI- Iodide
9 [8] supplu Doyo y radionuchdes/radiopharmaceutical otheo st r institutions Yes If yes, whic oftenw h ho one 9d san hospitalsHopefullyTwo other and yes research institutions
[9] Is medical research/diagnosis earned out on site/off site9 Medical research carriedis both siteout off on and site
siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a Are you engaged in nuclear reaction cross-section measurements9 Yes b Which type of nuclear data do you use9
Reaction cross sections Yes Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer fo s 9 Yes
84 FINLAND FIN-1
[1] Institute: University of Helsinki Postal Address- Laboratory ofRadiochemicals, PL55 FIN-00014 Helsinki
Telephone. 358-919140133 Fax/E-mail 358-91911; esko karttunen@helsinh fl
[2] Person m-charge. Esko Karttunen (Title/Position)
Other senior staff
[3] Typ cyclotrof eo n Manufacturer: IBA Model: Cyclone 10/5
Year (i) of installation- 1997 (planned for October) (n) of any major reconstruction:
[4] Particle beams available-
, *Be Dual Beams :%,;* A&„ H * • -i »*&& 3 : Beam energies/Range 10 5 (MeV) Typical currentt m s 80 40 (HA) Employed ext (MA)
Hour weer spe k machin operation i s ei n (excluding maintenance) Installation underway
Hours per week employed in radionuchde production
Hour weer spe k machine maintenance:
Additional applications of the cyclotron
Radiotherapy/Activation Analysis/Radiobiology/Physics
Others
85 [5] Radionuchdes produced:
Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
] [6 Radionuchdes planne producee b o dneae t th rd m future :
[7] Major radiopharmaceuticals produced:
supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? If yes, whic oftenw h ho one ?d san
medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site?
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nucleadm Ar r. [10 a reactio] n cross-section measurements? b. Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for trammg/expenence?
86 FINLAND FIN-2
[1] Institute: Turku PET Centre Postal Address: Accelerator Laboratory Abo Akademi, Porthansgatan 3 FIN-20500 Turku
Telephone: 358-2-2654 608 Fax/E-mail: 358-2-2654912; [email protected]
[2] Person in-charge: Sven-JohanDr. Heselius (Title/Position) Director
Other senior staff: OlofSolin; Jorgen Bergman; Jan-OlofLill; UlfHdllsten; Stefen Johansson; Erkki Stenvall; OlofErikssonPer
] [3 Typ cyclotronf eo : AVF Manufacturer: D. V. Efremov Institute Model: MGC-20
installationf Yearo ) (i : : 1974 (ii) of any major reconstruction:
] [4 Particle beams available:
'H *K 'He 'He Dual Beams
Beam energies/Range 3-20 6-10.5 9-28 12-21 (MeV) Typical currentt in s 300 300 80 80 (uA) Employeext d 30 30 20 20 (HA)
Hours per week machine is in operation (excluding maintenance): 42
Hour weer spe k employe radionuclidn di e production: 32
Hours per week machine maintenance: 8
Additional applications of the cyclotron: Atomic physics research Particle Induced X-ray Emission (PIXE) analysis Particle Induced Gamma Emission (PIGE) analysis Nuclear Reaction Analysis (NRA) Radiotherapy/Activation Analysis/Radiobiology/Physics:
87 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
"C N2 + 0.1%O2 37 10-15 batches/week ISp IS H2 0 37 3-6 (>94%) batches/week 4JK 998%)(99 Ar 20MBq 4 batches/year
[6] Radionuchdes planne producee b o dneat e th r n di future : <3N, 76Br
[7] Major radiopharmaceuticals produced: 1SF-FDG, '*F-6-Fluoro-L-Dopa 18F-FTHA I8F-CFT '8F-Fluonde "C-CFT, "C-MHED, "C-FLB457, "C-NMSP, "C-Flumazeml "C-NNC756, "C-Methionine, "C-Raclopride supplu yo o y D radionuchdes/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? K, 4 batches/year '"F-FDG, batches/month2
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site? On site
siten Ifo , indicate imaging devices available number
*511KeVSPET 2 * Gamma camera 4 Singl* e Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 2
[10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use?
Reaction cross sections Yes Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
88 FINLAND FIN-3
[1] Institute: Turku PET Centre Postal Address: Kiinamyllynkatu 4-8 FIN-20520 Turku
Telephone: 358-2-2611860 Fax/E-mail: 358-2-2318191; [email protected]
[2] Person in-charge: Hannu Sipila (Title/Position)
Other senior staff: Mika Teras; Kalevi Eklund Kari Lindberg
[3 ] Typ cyclotronf eo : Positive Ion H Manufacturer: IBAsa Model: Cyclone3
Year: (i) of installation: 1992 (ii) of any major reconstruction:
] [4 Particle beams available:
*H *K JHe "He Dual Beams
Beam 3.8 energies/Range (MeV) Typical currents int 80 - 100 (uA) Employed ext 50-60 (uA)
Hours per week machine is in operation (excluding maintenance): 10
Hours per week employed in radionuclide production: 10
Hours per week machine maintenance: 8 hours/month
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others: Blood flow in human tissue
89 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch n t*\T o N2 0.3-5 GBq/mm week4per
[6] Radionuchdes planne producee b o dneae t th rn di future :
[7] Major radiopharmaceuticals produced- I5O- Water O-Carbon Monoxide !5O-Oxygen
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No If yes, which ones and how often?
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site? On site
If on site, indicate imaging devices available number
*511 KeVSPET 2 Gamm* a camera 4 * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? No b. Which type of nuclear data do you use?
Reaction croso sN sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
90 FRANCE FRA-1
[1] Institute: Centre d'Exploration et de Recherche Medicales par Emission de Positrons (CERMEP) Postal Address: Cyclotron Biomedical Lyonde Boulevard59 Pinel F-69003 Lyon
Telephone: 33-4-72688600 Fax/E-mail: 33-4-72688610
[2] Person in-charge: Dr. D. Le Bars (Title/Position) Head of Radiochemistry
Other senior staff: G. Galy; LandaisP. D. Comar
[3] Type of cyclotron: Positive Ion Manufacturer: CGR-MeV Model: Cypris 325
Year: (i) of installation: 1987 (ii) of any major reconstruction:
[4] Particle beams available:
, „; - -£4.IUT ,-, dtf&&$$&2»!iu.f.-!JSfc«aSs^nr , -, ,|He „; "He Baal Beams ~*v«- *i>
Hour weer spe k machin operation i s ei n (excluding maintenance):
Hour weer spe k employe radionuclidn di e production:
Hours per week machine maintenance:
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
91 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C "W 75 weekper 5 "N month1per n "0 2.8 o 14N continuous 4 per week 33 MBqper injection >* IS F H2 O (95%) 20 4 per week enriched H2 O recovery
[6] Radionuchdes planne producee b o dneat e th r dm future :
[7] Major radiopharmaceuticals produced. O- Water and clinical gases C-Methionine," !1C-Acetate, !lC-Flumazenil, "C-Raclopride, I!C-MHED N-Ammoma I8F-FDG, 18F-Fluoro-L-DOPA
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san ft I F-FDG per/monthweekper one one to medicas I ] [9 l research/diagnosi siten O s earnesite/ofn o t dou f site?
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2
[10] a. Are you engaged in nuclear reaction cross-section measurements9 No b Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience?
92 FRANCE FRA-2
[1] Institute: Centre Antoine Lacassagne Postal Address: Laboratoire Cyclotrondu 227 Avenue de la Lanterne F-06200Nice
Telephone: 33-4-92031070 Fax/E-mail: 33-4-92031095
[2] Person in-charge: Dr. Pierre Mandrillon (Title/Position) Head of Cyclotron Laboratory
Other senior staff: N. Fietier
[3] Type of cyclotron: Compact Isochronous - Negative Ions Manufacturer: Cente antoine Lacassagne Model:
installationf Yearo ) (i : : 1990 (ii) of any major reconstruction:
[4] Particle beams available:
•a j *H ^He *He Dual Beams
Beam energies/Range 50 -65 25-32 (MeV) Typical currentt in s 40 20 (uA) Employed ext 40 20 (uA)
Hours per week machine is in operation (excluding maintenance): 8
Hour r weespe k employe radionuclidn di e production: notstartedyet
Hour weer spe k machine maintenance: 2
Additional applications of the cyclotron:
Radiotherapy/Activation Analysis/Radiobiology/Physics: Radiotherapy
Others:
93 [5] Radionuchdes produced
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
[6] Radionuchdes planned to be produced in the near future 1818F0(p,by n)for ISF-FDG
[7] Major radiopharmaceuticals produced Plan beginto 1998in
supplu yo o yD radionuchdes/radiopharmaceutical[8] otheo st r institutions''' If yes, which ones and how often9
medicas I [9] l research/diagnosis earnesite/ofn o t dou f site9 If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i ra [10reactio] n cross-section measurements9 b Which type of nuclear data do you use 9 Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for trammg/expenence9 Yes
94 FRANCE FRA-3
[1] Institute: Centre National Recherchela de Scientifique Postal Address: Centre d"Etudes et de Recherches Par Irradiation (CNRS-CERI) Feroleriela de 3arue F-45071 Orleans Cedex2
Telephone: 33-2-38255410 Fax/E-mail: 33-2-386302 71; [email protected]
[2] Person in-charge: G. Blondiaux (Title/Position) Director of the CERI
Other senior staff: G. Gain
[3] Type of cyclotron: Isochronous Manufacturer: CGRMeV Model:
installationf Yearo ) (i : : 1974 majoy an f ro reconstruction(ii) :
[4] Particle beams available:
*H *H *He "He Dual Beams
Beam energies/Range 5-35 5-25 10-60 10-50 (MeV) Typical currents int 70 40 40 (UA) Employed ext 40 40 (HA)
Hours per week machine is in operation (excluding maintenance): 64
Hours per week employed in radionuclide production: 10-12
Hours per week machine maintenance: 8
Additional application cyclotrone th f so : Charged particle and fast neutron activation analysis Production of defects in semi-conductors
Radiotherapy/Activation Analysis/Radiobiology/Physics: hours ofthe 25% Neutron therapy Material characterization Irradiation of electronic devices with neutrons (10l2/cm2/s) Analytical applications 17% of the hours Actinide irradiations 25% of the hours
95 [5] Radionuchdes produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch aimKr "Kr 0,2 2 per week 2 x 30 mm 2MU "*Th 2 per week 5hr ^Pu -"u 2 per week 5hr
[6] Radionuchdes planned to be produced in the near future:
[7] Major radiopharmaceuticals produced:
[8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san
[9] Is medical research/diagnosis earned out on site/off site? On site
If on site, indicate imaging devices available number
*511 KeVSPET * Gamma camera 7 Singl* e Photon Tomography (SPET) Positro* n Emission Tomography (PET) engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No b Which type of nuclear data do you use7
Reaction cross sections Yes Thics kYe target yields Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
96 FRANCE FRA-4
[1] Institute: Service Hospitaller Frederic Joliot Postal Address: C.E.A. Direction Sciencesdes Vivantdu 4, Place du General Leclerc F-91406 Orsay
Telephone: 33-1-69867704 Fax/E-mail: 33-1-69807768; [email protected]
[2] Person in-charge: C. Crouzel (Title/Position)
Other senior staff: F. Dolle; RoedaD. M. Ponchant; LochC.
] [3 Type cyclotronf o : Compact Cyclotron (variable energy) Manufacturer: CGR-MeV Model: 520
Year: (i) of installation: 1975 majoy an (iif r o )reconstruction : 1996 1997&
] [4 Particle beams available:
'H *H "He *He Dual Beams
Beam energies/Range 20 14.5 30 29 (MeV) Typical currents int (uA) Employed ext 30 30 15-20 15-20 (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): 25-30
Hours per week employed in radionuclide production: 25-30
6 Hour weer spe k machine maintenance:
Additional applications of the cyclotron:
Radiotherapy/ Activation Analysis/Radiobiology/Physics:
Others:
97 [5] Radionuclides produced:
Radionuctide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch weekper 5-10 n"C "N 40 o 5-8 per week JSp na'Ne 10 2 per week «F ,o0 3-4 2-4 per week >«p H2'*0 30 3-5weekper enriched 8 H2' 0 recovery /0Br na'As MBq 400 week2per
[6] Radionuclides planned to be produced in the near future:
[7] Major radiopharmaceuticals produced: 18F-FDG, '*F-DOPA, I8F-Oligonudides, l8F-Spiperone "C-Flumazenyl, "C-MQNB, 7lC-CGP I5O-Water Br-FLB,
[8] supplu Doyo y radionuclides/radiopharmaceutical otheo st r institutions? Yes If yes, which ones and how often? We shall supply IKF-FDG of hospitals to thisend the by year with helpthe ofds-Bio (ORIS-Industry)
[9] Is medical research/diagnosis carried out on site/off site? On site
If on site, indicate imaging devices available number
*511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 3 engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
98 GERMANY GFR-1
[1] Institute: Rheinisch- Westfalische Technische Hochschule Postal Address: Klinikfuer Nuklearmedizin Universitaetsklinikum D-52057 Aachen
Telephone: 49-241-8088740/1 Fax/E-mail: 49-241-8888520
[2] Person in-charge: Univ. Prof. Dr.med. BullU. (Title/Position)
Other senior staff: B. Mueller
[3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDSlll
Year: (i) of installation: 1997/1998 (ii) of any major reconstruction:
[4] Particle beams available: - *%r "i tlD. '., KH ^ **• ^He "He Dual Beams ,*.'. Beam energies/Range 11 yes (MeV) Typical currents int (HA) Employet ex d (uA)
Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway
Hour weer spe k employe radionuclidn di e production:
Hours per week machine maintenance:
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
99 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) frequency Comments Produced (enrichment) batcr pe h
"0 "N+ 1%O2 74 (purity 99.999%)
] [6 Radionuclides planne producee b o dneat e th rn di future :
[7] Major radiopharmaceuticals produced: (planned)
'5O-Water
supplu [8]yo o y D radionuclides/radiopharmaceutical otheo st r institutions? No If yes, whic oftenw h ho one ?d san
[9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellows for training/experience?
100 GERMANY GFR-2
[1] Institute: Zentralklinik Bad Berka GmbH Postal Address: PET Centre Robert Koch Allee 9 D-99437 BerkaBad
Telephone: 49-364-5850 Fax/E-mail: 49-364-5842180; [email protected]
[2] Person in-charge: Prof. Richard BaumP. (Title/Position)
Other senior staff:
[3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS111
Year: (i) of installation: 1997 (ii) of any major reconstruction:
[4] Particle beams available:
AH *n JHe *He Dual Beams
Beam energies/Range 11 yes (MeV) Typical currents int (HA) Employed ext (HA)
Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway
Hour weer spe k employe radionuclidn di e production:
Hour weer spe k machine maintenance:
Additional application cyclotrone th f so :
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
101 ] [5 Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
[61 Radionuclides planned to be produced in the near future: !3N,"C, /l/3/C/ F 15O, t *
[7] Major radiopharmaceuticals produced: (planned) 18F-FDG, 'fN-Ammonium, C-Acetate 1}O-Water/gas. !'C-Methionine
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? This is planned for 1998
[9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number
*511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sections Thick target yields Decay data
[11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes
102 GERMANY GFR-3
[I] Institute: Universitdtsklinik Ruhr-Universitatder Bochum Postal Address: Herz und Diabeteszentrum NRW Georgstrasse 11 D-32545 Bad Oeynhausen
Telephone: 49-5731-971865 Fax/E-mail: 49-5731-971862
[2] Person in-charge: Prof. Gunawan Notohamiprodjo (Title/Position) Director, Institutfur Biophysik, Radiopharmazie und Nuklearmedizin
Other senior staff: Petra Gerken; Sytse Zijlstra
[3] Type of cyclotron: Negative Ion Manufacturer: IBA Model: Cyclone 18/9
Year: (i) of installation: 7994 (ii) of any major reconstruction:
] [4 Particle beams available:
'H *H *He "He Dual Beams
Beam energies/Range 18 9 yes (MeV) Typical currents int 20 25 (uA) Employed ext 20 20 (uA)
Hours per week machine is in operation (excluding maintenance): 20
Hour weer spe k employe radionuclidn di e production: 20
Hour weer spe k machine maintenance: 2 days monthper
Additional application cyclotrone th f so :
Radiotherapy/ Activation Analysis/Radiobiology/Physics:
Others:
103 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h IJ N H2O+Ethanol 4 36 per week n"C N2+02 7 5 per week o N2 37 week1per ISp S H2' O (>98%) 15-45 week5per
[6] Radionuclides planne producee b o dneat e th r n di future :
[7] Major radiopharmaceuticals produced: 18F-FDG, lgFTHA !3N-Ammonia "C-Acetate, C-Methionine," "C-Carazolol >5 O-Water, !5O-Butanol
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? I8FDG, I8Fluoride every day
[9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number
*511KeVSPET 1 * Gamma camera 2 * Single Photon Tomography (SPET) 2 * Positron Emission Tomography (PET) 1
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use?
Reaction cross sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
104 GERMANY GFR-4
[1] Institute: Forschungszentrum Rossendorf Postal Address: Central Department AcceleratorsNew P.O. Box 510119 D-01314 Dresden
Telephone: 49-351 2603283 Fax/E-mail: 49-351-2603690
[2] Person in-charge: Dr. Hartmut Guratzch (Title/Position) Head of Department
Other senior staff: Hartmut Buttig Rudolf Bruckner
[3] Type of cyclotron: U-120 Manufacturer: NIIEFA PetersburgSt. Model:
installationf Yearo ) (i : : 1958 majoy an f ro (iireconstruction) : 1989
[4] Particle beams available:
'H *H JHe "He Dual Beams
Beam energies/Range "/ 14 28 (MeV) 7 Typical currents int (uA) Employed ext 50 50 20 (uA)
Hours per week machine is in operation (excluding maintenance): 50
Hour weer spe k employe radionuclidn di e production: 10
Hours per week machine maintenance: 5
Additional application cyclotrone th f so : Radiochemistry Thin Layer Activation
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others:
105 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "7i na'Sc a/yf/mSr na'Rb VJMo na'Zr '"At na'Bi
[6] Radionuclides planned to be produced in the near future:
[7] Major radiopharmaceuticals produced:
supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? External application ofradionuclid.es generally
[9] Is medical research/diagnosis carried out on site/off site? No siten Ifo , indicate imaging devices available number
*511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET)
[10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r dat?yo o ad
Reaction cross sYe sections Thick target yields Yes s Ye Decay data
[11] Does your institute accept IAEA research fellows for training/experience? Yes
106 GERMANY GFR-5
[1] Institute: Forschungszentrum Rossendorf Postal Address: Institutfur Bioanorganische und Radiopharmazische Chemie P.O.510119Box D-01314 Dresden
Telephone: 49-351 2603170 Fax/E-mail: 49-351-2603232; [email protected]
[2] Person in-charge: Prof. Habil B. Johannsen (Title/Position) Director of the Institute
Other senior staff: J. Steinbach; St. Preusche
[3] Typ cyclotronf eo : Negative Ion Manufacturer: IBA Model: Cyclone 18/9
Year: (i) of installation: 1994/96 majory an (iif o )reconstruction :
[4] Particle beams available: *H ** 'He 'He Dual Beams Beam energies/Range 18 9 yes (MeV) Typical currentt in s 50 30 (uA) Employet ex d 25 15 20 (HA)
Hours per week machine is in operation (excluding maintenance): 15
Hours per week employed in radionuclide production: 15
Hours per week machine maintenance: 2-3
Additional applications of the cyclotron: educationFor purposes
Radiotherapy/Activation Analysis/Radiobiology/Physics:
Others: OnlyPET for educationFor purposes scientific research concentratedis to development ofradiotracer labelling and radiotracer development. Targetry development highfor current water target progressin is
107 [5] Radionuclides produced:
Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch
"C N2 +0.5%O2 0.5-80 "F H^O (97%) 20-90 weekr pe 5 3- activity dependson request ISp u ' Ne +0,2%F2 4-12 2 per week mainlyfor research
[6] Radionuclides planned to be produced in the near future: I5O, 13N depending on medical requirements
[7] Major radiopharmaceuticals produced: 1SF-FDG, ™F-Altanserin I8F-DOPA, l8F-16-Fluorestradiol "C-McNeil5652-Z
[8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 18F-FDG 3 per week
[9] Is medical research/diagnosis carried out on site/off site? Yes
siten Ifo , indicate imaging devices available number
*511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 7
[10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad
Reaction cross sYe sections Thick target yields Yes Decay data Yes
[11] Does your institute accept IAEA research fellows for training/experience? Yes
108 GERMANY GFR-6
[I] Institute: Institute for Medical Radiation Physics Postal Address: Hufelandstrasse 55 D-4 5147 Essen
Telephone: 49-201-7234170 Fax/E-mail: 49-201-7235965
[2] Person in-charge: Prof. J. Rassow (Title/Position)
Other senior staff: G. Hudepohl St. Preusche
[3 ] Type of cyclotron: Positive Ion, Sector-focused Manufacturer: The Cyclotron Corporation Model: CV28
installationf Yearo ) (i : : 1975 (ii) of any major reconstruction:
[4] Particle beams available:
*H ' ' ;-- *H 'He Beam energies/Range 24 14 36 28 (MeV) Typical currentt in s 120 120 80 *80 (UA) Employed ext <90 <80 £30 <30 (uA) (30) Hours per week machine is in operation (excluding maintenance): 40 Hours per week employed in radionuclide production: 24 Hour weer spe k machine maintenance: 4 Additional application cyclotrone th f so : Neutron therapy Dosimetry Radiobiology Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 109 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N <10 week4per "0 MN <1.5 GBq/min 2 per week >*F "0 <20 2 per week enriched water recovery '"I '"Te <55 2 per week enriched Te '"I '"Te <0.37Bq 2 per week [6] Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: 15O- Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 18F-FDG 3 per week medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera Yes Singl* e Photon Tomography (SPET) Yes * Positron Emission Tomography (PET) Yes engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurementso N ? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 110 GERMANY GFR-7 [1] Institute: J. W. Goethe University Postal Address: Clinic of Nuclear Medicine Theodor-Stern-Kal7 D-60590 Frankfurt Telephone: 49-69-63015459 Fax/E-mail: [email protected] [2] Person in-charge: Prof.Nor G. (Title/Position) Director Other senior staff: U. W. Scherer ] [3 Typ cyclotronf eo : Negative / D~ PT Ion Manufacturer: IBA Model: Cyclone 18/9 Year: (i) of installation: 1998 (ii) of any major reconstruction: [4] Particle beams available: lfl *H 'He "He Dual Beams Beam energies/Range 18 9 (MeV) Typical currents int (HA) Employet ex d (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 111 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b neao de t th rn di future : 15!8F,0,"C, '*N, "mTc, 68Ga [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? If yes, whic oftenw h ho one ?d san medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET 7 Gamm* a camera 2 * Single Photon Tomography (SPET) 1 Positro* n Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections No Thico kN target yields o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 112 GERMANY GFR-8 [1] Institute: Euro-PETGmbH Postal Address: Hugstetlerstrasse55 D-79106 Freiburg Telephone: 49-761-2709201 Fax/E-mail: 49-761-2709200 ] [2 Person in-charge: Prof. Dr. med. Peter Reuland (Title/Position) Other senior staff: [3] Typ cyclotronf eo : Negative Ion Manufacturer: GE Model: PETTrace installationf Yearo ) (i : : 1996 majoy an (iif r o )reconstruction : [4] Particle beams available: J 4 'H ** He He Dual Beams Beam energies/Range 16.4 8.2 yes (MeV) Typical currentt in s (uA) Employed ext (MA) Hours per week machine is in operation (excluding maintenance): 25 Hours per week employed in radionuclide production: 20 Hour weer spe k machine maintenance: 2 Additional application cyclotrone th f so : Only production of radiopharmaceuticals Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 113 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 'JN 10-20 week8per >« e F H2' O (98%) 50-70 week10per [6] Radionuclides planned to be produced in the near future: "C-Carbon Monoxide, "C-Carbon Dioxide !5O-Water, '5O-Carbon Monoxide, C15-Oxygen [1] Major radiopharmaceuticals produced: I8F-FDG 10per week N-Ammonia 8 per week weekper 5 10 F-Fluoride •* supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Planned If yes, whic oftenw h ho one ?d san Not at the moment, but in future [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET1 ) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 114 GERMANY GFR-9 [1] Institute: UKE-Cydotron Postal Address: Luruper Chaussee 149 D-22761 Hamburg Telephone: 49-40-89982968 Fax/E-mail: 49-40-89982960 [2] Person in-charge: BrunoDr. Nebeling (Title/Position) Other senior staff: Uve Kirchner [3] Typ cyclotronf eo : Isochronous Manufacturer: Philips Model: 140/IV Year: (i) of installation: 1968 (ii) of any major reconstruction: [4] Particle beams available: 'H *H "He 4He Dual Beams Beam energies/Range 4-30 2-16 6-42 6-36 (MeV) Typical currents int 120 (uA) Employet ex d 15-25 (HA) Hours per week machine is in operation (excluding maintenance): 10-20 Hours per week employed in radionuclide production: 10-20 0 2 - 0 1 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 115 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C 2 O 5% N+ 2 GBq 50 1-4weekper ISp [61 Radionuclides planne producee b o dneae t th rn di future : 2"At,aGe [7] Major radiopharmaceuticals produced: 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? F-Fluoride ^F-FDG Daily from Tuesday Fridayto medicas I ] l[9 research/diagnosi siten O s carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomograph/ y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 116 GERMANY GFR-10 [1] Institute: Medizinische Hochschule Hannover (MHH) Postal Address: Abteilung Nuklearmedizin and Spezielle Biophysik D-30623 Hannover Telephone: 49-511-5325606, 3085 Fax/E-mail: 49-511-5322315 [2] Person in-charge: HelmekeDr. (Title/Position) Head Cyclotron ofthe Group Other senior staff: G.-J. Meyer [3] Type of cyclotron: Isochronous, Variable energy Manufacturer: Scanditronix Model: MC35 Year: (i) of installation: 1976/77 majoy an f ro (iireconstruction) : [4] Particle beams available: 'H *& *He "He Dual Beams Beam energies/Range 7.535 - 3.8-18 5.6-47 7.5 - 35 (MeV) Typical currents int (uA) Employed ext 65 65 30 30 (uA) Hours per week machine is in operation (excluding maintenance): including20 stand-by Hour weer spe k employe radionuclidn di e production: including8 stand-by Hours per week machine maintenance: 3 including stand-by Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 117 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2+5%2 O 26 year40per li N H2O 4- 5mmol 4 190yearper ethanol n o Nj+J%2 O 4 170 per year >« F 96%^(> HO 2 17.5 350 per year >* F Ne+0.1%F2 4.5 3 50 per year [6] Radionuclides planne producee b o dneat e th rn di future : ] [7 Major radiopharmaceuticals produced: 11C-Methionine, C-Acetate 15O-Water 13N-Ammonia !8F-FDG, lsF-Fluorouracil [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? On site If on site, indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i . r a reactio[10] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 118 GERMANY GFR-11 [1] Institute: German Cancer Research Centre (DKFZ) Postal Address: Im Neuenheimer Feld 280 D-69120 Heidelberg Telephone: 49-6221-422550-3 Fax/E-mail: 49-6221 422572 [2] Person in-charge: Gerd Wolber (Title/Position) Head of the Cyclotron Group Other senior staff: Wolfgang Maier-Borst Franz Oberdorfer [3] Type of cyclotron: Isochronous, Negative Ion Manufacturer: Scanditronix Model: 32NIMC installationf Yearo ) (i : : 1992 (ii) of any major reconstruction: [4] Particle beams available: ZH 'H - -r , /He *He Dual Beams " ? - " <, & •£ *. Beam energies/Range 16-32 8.5-16 (MeV) Typical currentt m s 100 100 (uA) Employed ext 20-30 20 (uA) Hours per week machine is in operation (excluding maintenance): 50 Hours per week employed in radionuclide production: 40 Hour weer spe k machine maintenance: 5 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Radiobiology, Physics Others: The Department is a long-standing WHO Reference Institute Nuclearfor Medicine 119 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N 37 5 -6 per week "0 14N 0.7 per 0.5 h day 2-3per weekper day 4 "F e JS H2' O (98%) 12 weekper 5 enriched H2 O recovery "F-F-, '"Ne 0,7 weekper 3 s'Rb "Kr 2.2 week2per enriched^Kr recovery [61 Radionuclides planne producee b o dneat e th rn di future : 4 5. 6 . 8r 75 , Br , Ge , [7] Major radiopharmaceuticals produced: I8F-FDG, '*F-6-F-DOPA,. ™F-5-Fluorouracil 15O-Water "C:C: "C-Carbon"C-Cc Monooxidem "C-C.arbon dioxide, "C-AIB, "c -Acetate, "C-Ethanol C-DTIC, "C-Sch 23390 supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes. whic oftenw h ho one ?d san Generator: Rb-Kr- 81 2times week Centre,1 per to I8F-DOPA: times2 week centres2 per to Capacity of the system has been designed to supply extra mural regional centresPET medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511 KeVSPET 1 * Gamma camera * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 120 GERMANY GFR-12 [1] Institute: Forschungszentrum Jiilich GmbH Postal Address: Institutfur Nuklearchemie D-52425 Jiilich Telephone: 49-2461-614141 Fax/E-mail: 49-2461-612535 [2] Person in-charge: Prof. H.H. Coenen (Title/Position) Other senior staff: S.M. Qaim; GailR. HamacherK. [3] Type of cyclotron: Baby Cyclotron Manufacturer: Japan Steel Works Model: BC1710 Year: (i) of installation: 1987 majoy an (iif ro )reconstruction : [4] Particle beams available: *H ZH 3He "He Dual Beams Beam energies/Range 17 10 (MeV) Typical currentt in s (HA) Employed ext 30 20 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 35 Hour weer spe k employe radionuclidn di e production: 35 Hour weer spe k machine maintenance: 5 Additional applications of the cyclotron: Radiopharmaceutical development Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 121 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N2gas 60 week4per "N H2O 15 2 per week ,Sp a H2' O (96%) 50 5 per week enriched H^O recovery ] [6 Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: I8F-FDG, )8F-Fatty acids C-Acetate, 11C-Methionine N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes yesf I , whic oftenw h ho one ?d san 18FDG daily to several clinics [9] Is medical research/diagnosis carried out on site/off site? Both If on site, indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomograph; y (SPET) * Positron Emission Tomography (PET) 2 engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thico kN target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 122 GERMANY GFR-13 [1] Institute: Forschungszentrum Jiilich GmbH Postal Address: Institutfur Nuklearchemie D-52425 Jiilich Telephone: 49-2461-614141 Fax/E-mail: 49-2461-612535 [2] Person in-charge: Prof. H.H. Coenen (Title/Position) Other senior staff: M. Holschbach ] [3 Typ cyclotronf eo : Fixed energy, two particle Manufacturer: GE Model: PETTrace Year: (i) of installation: 1997 majoy an (iif r o )reconstruction : [4] Particle beams available: *H ^ 3He "He Dual Beams Beam energies/Range 8.4 (MeV) Typical currents int (uA) Employet ex d 30 (uA) Hours per week machine is in operation (excluding maintenance): Cyclotron operation is just beginning Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 123 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "0 N2gas 60 daily [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: !5O-nbutanol, 15O-Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? The machine will be extensively used for patient studies with O- labelled compounds medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site siten o ,f I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 124 GERMANY GFR-14 [1] Institute: Forschungszentrum Jiilich GmbH Postal Address: Institutfur Nuklearchemie D-52425 Jiilich Telephone: 49-2461-614141 Fax/E-mail: 49-2461-612535 [2] Person in-charge: DworschakF. Dr. (Title/Position) Other senior staff: H.H. Coenen S.M. Qaim [3] Typ cyclotronf eo : Variable Energy Compact Manufacturer: The Cyclotron Corporation Model: CV28 Year: (i) of installation: 1976 (ii) of any major reconstruction: 1986, 1991, 1997 [4] Particle beams available: 4H 11 *He "He Dual Beams Beam energies/Range 6-24 3-14 15-36 10-28 (MeV) Typical currentt in s 100 100 100 100 (HA) Employed ext 30 20 15 20 (HA) Hours per week machine is in operation (excluding maintenance): 56 Hours per week employed in radionuclide production: 28 Hour weer spe k machine maintenance: 7 Additional applications of the cyclotron: Materials research Activation analysis Neutron induced reactions Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 125 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) frequency Comments Produced (enrichment) batcr pe h n o W? (gas) 60 2 per week >* IS F Ne 15 1 per week FF2 JSK KC1 400 on demand "Se Cu3As 150 on demand s'mRb s'Krgas(90%) 400 on demand so y w SrCo3 (95%) 400 on demand target recovery V4m V4 Tc MoO3(97%) 1 on demand target recovery Ui '"I TeO2 (> 96%) 150 I per fortnight dry distillation I4/ 4 Gd '* Sm203 (95%) 400 on demand target recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 15butanoln O - supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? On collaborative basis to several institutions [9] Is medical research/diagnosis carried out on site/off site? Both siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) 7 Positro* n Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields No s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 126 GERMANY GFR-15 [1] Institute: Forschungszentrum Karlsruhe (FZK) Postal Address: Cyclotron Laboratory P.O. Box 3640 D-76Q21 Karlsruhe Telephone: 49-7247-822433 Fax/E-mail: 49-7247-823156 [2] Person in-charge: Dr. H. Schweickert (Title/Position) Director, Cyclotron Laboratory Other senior staff: V. Bechtold FehsenfeldP. ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: CP42H installationf Yearo ) (i : : 1984 (ii) of any major reconstruction: [4] Particle beams available: 'H ZH "He 4He Dual Beams Beam energies/Range 15-42 (MeV) Typical currentt in s 200 (HA) Employet ex d 200 (HA) Hours per week machine is in operation (excluding maintenance): 70 Hour weer spe k employe radionuclidn di e production: 50 Hour weer spe k machine maintenance: Routine maintenance over Christmas only Additional application cyclotrone th f so : Activation of machine parts for wear studies Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 127 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Rb a'Kr (99%) 20 5 per week U,j U4Xe (99%) 40 5 per week ultra pureI [6] Radionuclides planne producee b do neat e th rn d i future : 225 226Ac2n) via Ra (p, ] [7 Major radiopharmaceuticals produced: 18\F-FDG, 123 [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 3 Pharmaceutical companies 12 Hospitals [9] Is medical research/diagnosis carried out on site/off site? No siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . ra reactio[10] n cross-section measurements? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Seldom Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 128 GERMANY GFR-16 [I] Institute: Forschungszentrum Karlsruhe (FZK) Postal Address: Cyclotron Laboratory P.O. Box 3640 D-76021 Karlsruhe Telephone: 49-7247-822433 Fax/E-mail: 49-7247-823156 [2] Person in-charge: Dr. H. Schweickert (Title/Position) Director, Cyclotron Laboratory Other senior staff: V. Bechtold; P. Fehsenfeld [3] Typ cyclotronf eo : Positive Ion Manufacturer: AEG Model: installationf Yearo ) (i : : 1964 majoy an (ii f r) o reconstruction: [4] Particle beams available: *H H 1 : ., *He "He Dual Beams Beam energies/Range 52 104 (MeV) Typical currentt in s 40 50 (HA) Employet ex d 20 25 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Routine maintenance over Christmas only Additional applications of the cyclotron: Activation of machine parts for wear studies Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 129 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 3 Pharmaceutical companies 12 Hospitals medicas I ] l[9 research/diagnosio N s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Seldom Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 130 GERMANY GFR-17 [1] Institute: Max-Planck-Institut Neurologischefur Forschung Postal Address: Gleueler Strasse 50 D-50931 Koln Telephone: 49-221-4726-0 Fax/E-mail: [2] Person in-charge: Prof. Wolf-Dieter Heiss (Title/Position) Director Other senior staff: Klaus Weinhard [3] Typ cyclotronf eo : Baby Cyclotron Manufacturer: Scanditronix Model: MC16 Year: (i) of installation: 1987 (ii) of any major reconstruction: ] [4 Particle beams available: 'H *H 'He *He Dual Beams Beam energies/Range 17 8.5 (MeV) Typical currents int 50 (uA) Employed ext 25 (UA) Hours per week machine is in operation (excluding maintenance): 15 Hour weer spe k employe radionuclidn di 5 1 e production: 4 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 131 [5] Radionuclides produced: Radionuctide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N 55 8 per week "0 MN 10 50 per week >«F "Ne 11 6 per week [6] Radionuclides planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: 18F-FDG, ™F~DOPA 15 15 15 15 O-H2O, O-Carbon Monoxide,. O-Carbon Dioxide,, O-Butanol "C-Methionine, !'C-Radopride, " C-Flumazenil supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean di Ar r. a reactio[10] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections No Thico kN target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? 132 GERMANY GFR-18 [1] Institute: Technischen Universitdt Miinchen Postal Address: Nuklearmedizinische Klinik PolHdinikund Ismaningerstr. 22 D-81675 Miinchen Telephone: 49-89-414045862970 Fax/E-mail: 49-89-4140 4841 [2] Person in-charge: Prof. M. Schwaiger (Title/Position) Other senior staff: Stocklin;G. Herz;M. ReidelG. H.J. Wester, Watzlowik,P. I Wolf [3] Type of cyclotron: Negative Ion Compact Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1993 majoy an (ii f r)o reconstruction: ] [4 Particle beams available: 1H *H JHe "He Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int (UA) Employet ex d 20-40 (uA) Hours per week machine is in operation (excluding maintenance): 9 Hour weer spe k employe radionuclidn di 9 e production: 2 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 133 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C na'N, 52 weekper 5 na n"N 'H,0 5.2 10 per week o '% (99%) 18.5 36 per week '«p a H2' O (96%) 37 week5per enriched water recovered [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG "C-Flumazenil, "C-Methionine, "C-Hydroxyephedrin, "C-Acetate N-Ammonia I5O-Water supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? isT-FDG Monday Friday- [9] Is medical research/diagnosis carried out on site/off site? On site, Research, Diagnosis If on site, indicate imaging devices available number *511KeVSPET 1 Gamm* a camera 4 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r dat?yo o ad Reaction cross sections Yes Thick target yields Yes o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 134 GERMANY GFR-19 [1] Institute: Universitdtsklinikum Tubingen (UKT) Postal Address: Interdisciplinary CentrePET Department of Nuclear Medicine Rontgenweg 15 D-72076 Tubingen Telephone: 49-7071-2987443 Fax/E-mail: 49-7071-296554 [2] Person in-charge: Prof. H.-Jurgen Machulla; Prof. BaresR. (Title/Position) Section ofRadiopharmazie; Director of Nuclear Medicine Other senior staff: [3] Typ cyclotronf eo : Negative Ion Manufacturer: GE Model: PETTrace installationf Yearo ) (i : : 1995 (ii) of any major reconstruction: [4] Particle beams available: *H "H "He *He Dual Beams Beam energies/Range 16.5 ± 0.1 8.2 ± 0.2 (MeV) Typical currents int 40 40 (HA) Employed ext 35 35 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 20 Hours per week employed in radionuclide production: 20 Hours per week machine maintenance: 0.5 Additional applications of the cyclotron: Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 135 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2+0.5% O2 40 week3per "c N2+0.5% O2 6 10 per week "N H2'°0 2 2 per week "0 N2+l% O2 6 4 per week "p H2'*O 20 5 per week S >«F H2' O 5 5 per week [61 Radionuclides planne producee b o dneae t th rn di future : 124*86y [7] Major radiopharmaceuticals produced: 2-'SF-FDG, 3-I8F-FDG, ISF-Fluoromisonidazole, I8F-Fluoroacetate 1!C-labelled Amphetamine derivates, "C-Ritalin, "C-Methionine, " C-Raclopride, C-Thymidine, C-O-Me-Glucose 15O- Water N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 18F-FDG once in two weeks medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511 KeVSPET * Gamma camera 5 Singl* e Photon Tomography (SPET) 3 Positro* n Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction croso sN sections Thick target yields No Decay data Yes [11] Does your institute accept IAEA research fellows for training/experiience? 136 GERMANY GFR-20 ] [1 Institute: University Hospital Ulm Postal Address: Department of Nuclear Medicine Robert-Koch-Strasse8 D-89081 Ulm Telephone: 49-731-5024981 Fax/E-mail: 49-731-5024512 [2] Person in-charge: Prof. S.N. Reske (Title/Position) Other senior staff: K. Grillenberger [3] Type of cyclotron: Negative Ion Manufacturer: IBA Model: Cyclone 18/9 installationf Yearo ) (i : : 1995 majoy an f r(ii o reconstruction) : [4] Particle beams available: ...... ^ . *H *He "He Dual Beams Beam energies/Range 18 9 yes (MeV) Typical currents int (uA) Employet ex d (uA) Hour weer spe k machin operation i s ei n (excluding maintenance)days)4 ( 5 1 ~ : Hour weer spe k employe days)4 radionuclid( n di 5 1 ~ e production: 5 ~ Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analy sis/Radiobiology/Phy sics: Others: 137 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C '% -50 1-2weekper "N H2"0 ~ i*? 1-2weekper "0 "N, -10 - 1 per -week ISr? 1*2 "Ne+0.2%2 F -10 weekper 1 - [6] Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: 18F-FDG, '*F-Fluoride C-Methionine N-Cisplatin [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 2 engageu yo [10e nuclean d]Ar i a. r reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 138 HUNGARY HUN-1 [1] Institute: Institute of Nuclear Research of the Postal Address: Hungarian Academy of Sciences P.O. Box 51 H-4001 Debrecen Telephone: 36-52-417266 Fax/E-mail: 36-52-416181 [2] Person in-charge: F. Tdrkdnyi; L. Tron (Title/Position) Head of Cyclotron Department; Head Centre ofPET Other senior staff: Kormany;Z. Kovacs;P. SzucsZ. L. Ando; F. Szelecsenyi, T. Marian; G. Horvath [3] Typ cyclotronf eo : Compact Isochronous Cyclotron Manufacturer: NIIEFA Russia Model: MGC20E Year: (i) of installation: 1985 (n) of any major reconstruction: 1997 [4] Particle beams available: '^IttHhfflj N -S e iH , e Dual Beams • >£&. Hour weer spe k machin operation i s ei n (excluding maintenance)4 9 : Hours per week employed in radionuclide production: 28 (56 every second week) Hours per week machine maintenance: 5 Additional application cyclotrone th f so : Neutron source (radiobiology, radiation hardness test, neutron activation, Thin Layer Activation (TLA), wear measurements, activation analysis (charged particle) Basic nuclear physics (in beam nuclear spectroscopy, astrophysical nuclear reactions) Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 139 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N 12 4 per week "0 I4N 10 20 per week "F S (97%)O 2 H 25 4 per week enriched H2' O recovery 6/Ga °'Zn (99%) 10 week1per enriched Zn recovery JJJI !^Te (95%) 6 1 per week enriched u*Te recovery [6] Radionuclides planned to be produced in the near future: N-Ammonia 15O-Water "C-Flumezinil inIn-DTPA '23I-mIBG, ml-lomazine ] [7 Major radiopharmaceuticals produced: 18F-FDG IS O-Butanol C-Methionine, C-Chlorostyryl caffeine, Ga-citric acid Na123I [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Na 123I - every 2 weeks 67Ga citric- acid every- weeks2 [9] Is medical research/diagnosis carried out on site/off site? Both siten Ifo , indicate imaging devices available number *511KeVSPET 1 Gamm* a camera 2 Singl* e Photon Tomography (SPET) I * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 140 INDIA IND-1 ] [1 Institute: Variable Energy Cyclotron Centre (VECC) Postal Address: 1/AF, Bidhan Nagar Calcutta 700 064 Telephone: 91-33-3371230 Fax/E-mail: 91-33-3346871 [2] Person in-charge: B.C.Dr. Sinha (Title/Position) Director Other senior staff: ] [3 Typ cyclotronf eo : Sector-focused Cyclotron (pole diametercm) 224 Manufacturer: VEC Centre Model: Individual design Year: (i) of installation: 1997 majoy an f (iiro )reconstruction : 7997 [4] Particle beams available: J ^, H vsr§SfflBt-'*«i-L*• - : - !He :• %e Dual Beams ' • '-$ ^f^3:"jr jff~ ?•; -J*' ™*~ ,£ * ' %?'• ' ™ "%. * ^.^^«Hl»**^-?',^ -^*^ *" Beam energies/Range 6.30 12.30 25.80 (MeV) Typical currents int 200 200 200 (uA) Employed ext 20 20 20 (MA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 16 : Hour weer spe k employe radionuclidn di 4 2 e production: 8 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Activation Analysis/Radiobiology/Physics Others: Nuclear Chemistry 141 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch <* S F H2' 0 5 no fixed recovered schedule enriched water 6'Ga natCu 8 once a week for R&D work at present '"In ""Ag1 8 no fixed schedule [6] Radionuclides planned to be produced in the near future: 201Tl [7] Major radiopharmaceuticals produced: 167Ga-Gallium citrate 111In-Indium chloride 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Regional Radiation Medicine Centre, Thakurpukur, Calcutta - weekly Radiation Medicine Centre, Mumbai - monthly medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurements? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 142 INDONESIA INS-1 [1] Institute: National Atomic Energy Agency, BAT AN Postal Address: PPR-Batan Kawasan Puspiptek Serpong 15310 Indonesia Telephone: 21-7563141 Fax/E-mail: 21-7560928 ] [2 Person in-charge: Silakhuddin (Title/Position) Head of Cyclotron Division Other senior staff: Tonny Heryanto; Budi Tarigan [3] Type of cyclotron: Positive Ion Cyclotron Manufacturer: CTI Model: CS30 installationf Yearo ) (i : : 1990 (ii) of any major reconstruction: 1995, modified to negative ion by IB A ] [4 Particle beams available: ^?"?a •„>r-:-'"«Ekv-- ,,.atTT, t - . - '.•10* ^e Dual Beams ** jv'~.*«a ,%.,-,: vapgs ••„• ' - 3 "\-: * f" ">• ;./-. :*>! '" ':?'. j"' >V * - "" Beam energies/Range 24-27 (MeV) Typical currentt in s 100 (HA) Employed ext 65 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 6 Hour weer spe k machine maintenance: 2 Additional applications of the cyclotron: We have a plan to use the cyclotron for charged particle activation analysis Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 143 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch ""77 «,JTI 13 sometimes [6] Radionuclides planne producee b neao de t th r n di future : We would like produceto I. 123, Unfortunately have we experts no facility and [7] Major radiopharmaceuticals produced: 77 chloride supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st rs institutionsYe ? If yes, which ones and how often? Sometimes depends on demand. The problem is on marketing, because we have no duty for the marketing. This is the duty of another division. medicas I ] l[9 research/diagnosio N s carrie site/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 144 IRAN, ISLAMIC REPUBLIF CO IRA-1 [1] Institute: Nuclear Research Centre for Agriculture Postal Address: and Medicine (NRCAM) P.O.31585-4395Box Karaj Telephone: 98-21-545747 Fax/E-mail: 98-261-411105 [2] Person in-charge: Prof. S.M. Haji-Saeid (Title/Position) Vice President ofAEOI & Director of Cyclotron Accelerator Department Other senior staff: H. Afarideh; Satari; Partovi; Rafii;Akbari, Shafiei [3] Typ cyclotronf eo : NegativeIon Manufacturer: ISA, Belgium Model: Cyclone 30 installationf Yearo ) (i : : 1995 (ii) of any major reconstruction: [4] Particle beams available: XH *H 'He "He Dual Beams Beam energies/Range 15-30 7-75 yes (MeV) Typical currents int (uA) Employet ex d 500 150 175 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 20-25 Hours per week employed in radionuclide production: 12-17 Hour weer spe k machine maintenance: 5 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 145 [5] Radionuclides produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch 0/Ga MZnO (98%) 0.1 weektwo 1per enrichedZn M recovery '"In na'Cd 0.5 weektwo 1per -""77 2(JiTl (98%) 0.037 -weekper 1 enriched ™*Tl recovery [6] Radionuclides planned to be produced in the near future: Sim'Kr - Rb generator ISF-FDG. 123, ] [7 Major radiopharmaceuticals produced: 2011\-Thallous Chloride 67Ga-Gallium Chloride III In-Indium Chloride supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? nuclearToall medicine centre countrythe in once weeka [9] Is medical research/diagnosis carried out on site/off site? Off site Presently off site, but in the near future will be on site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) * Dual head gamma camera with coincidence possibly [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 146 ISRAEL ISR-1 [I] Institute: Hadassah University Hospital Postal Address: Kiryat Hadassah P.O.B. 12000 11-91 120 Jerusalem Telephone: 972-2-6777931 Fax/E-mail: 972-2-6421203; [email protected] [2] Person in-charge: EyalDr. Mishani (Title/Position) Other senior staff: ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: IBA Model: Cyclone 18/9 installationf Yearo ) (i : : 1997 majoy an (ii f ro ) reconstruction: [4] Particle beams available: I *i:'-- ." '^•'4-Ty '~^"~; J; da|P2&f fcil-SS • ^RA " ': •4prA - -V Dual Beams ...flT', - ""* - - : . . - T• H ~", , . , *s- Beam 75 9 yes energies/Range (MeV) Typical currentt in s (UA) Employet ex d (uA) Hours per week machine is in operation (excluding maintenance): approx. 10 Hour weer spe k employe radionuclidn di e production: 10 Hour weer spe k machine maintenance: 4-5 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 147 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b o neade t th rn d i future : o 15 "c, [7] Major radiopharmaceuticals produced: 18'F-FDG N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Planned yesf I , whic oftenw h ho one ?d san We plan supplyto radionuclides nearthe futurein medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomographs Ye y (PET) engageu yo e nuclean di Ar r. a reactio[10] n cross-section measurements? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 148 ITALY ITA-1 [1] Institute: European Commission Postal Address: 1-21020 Ispra(VA) Telephone: 784385332 39 Fax/E-mail: 39 332 785281; [email protected] [2] Person in-charge: M. F. Strousnjder (Title/Position) Section Head Other senior staff: Bruenoni,C. Haanappel,C. A. SunderloetterV. D. J. [3] Typ cyclotronf eo : Variable Energy PositiveIon Manufacturer: Scanditronix Model: MC-40 installationf Yearo ) (i : : 1980 (ii) of any major reconstruction: [4] Particle beams available: 3 r JsfeatHJ^'B •*•% 11,,,'JO.ITc"C *%-,;i " ~; rrr-x^ff^,--:•"' lHe«-- •-T• Dnal Beams •U-: »Misi#.»-,*. r.: ?!!!;:^; Beam energies/Range 10-39 5-19 70-39 (MeV) Typical currentt in s 120 100 60 (uA) Employed ext 60 60 30 (uA) Hours per week machine is in operation (excluding maintenance): 25 Hour weer spe k employe radionucliddn i e production: 8 Hour weer spe k machine maintenance: 4 Additional applications of the cyclotron: Materials Research Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Significant investments are underway to support new activities 149 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h //J7 '"Xe 80 upto 2-3 per week [6] Radionuclides planne producee b o dneat e th rn di future : other radionuclidesand 18 PET F ] [7 Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, whic oftenw h ho one ?d san times3 weekto per up I medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? Offsite If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomography (PET) engageu yo e nuclean dAr i r. [10 a reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 150 ITALY ITA-2 ] [1 Institute: H.S. Raffaele Institute Postal Address: Centro Cyclotron/PET Via Olgettina, 60 1-20132 Milano Telephone: 39-2-2153056 or 26432716 Fax/E-mail: 39-2-2640390; fazio@mednuc. hsr.it [2] Person in-charge: Prof. Ferruccio Fazio (Title/Position) Other senior staff: Francesco Perugini; Sergio Todde Mario Matarrese; Assunta Carpinelli ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1988 (ii) of any major reconstruction: [4] Particle beams available: 4H •*• >-^E: 'He *He Dual Beams Beam energies/Range /; (MeV) Typical currents int 100 (uA) Employet ex d 20-40 (uA) Hours per week machine is in operation (excluding maintenance): 31 Hours per week employed in radionuclide production: 21 8 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 151 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 14 "C N2 +l% O2 75 10 per week research tests "N H2'°O + ethanol 7.5 week1per (<1%) n I3 o N2 (99+%) 0.8 week48per activation studies a >«F H2' O (96+%) 14 week4per yes [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: 18F-FDG, '*F-FESP 15 I5 O-Butanol, O-H2O C-Flumazenil, m-Hydroxy- C-efedrine N-Ammonia supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET 7 * Gamma camera 3 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 7 [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections No Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 152 ITALY ITA-3 [1] Institute: Istituto Nazionaleper lo Studio e la Cura Postal Address: dei Tumori (INI) Via Venezian1 1-20133 Milano Telephone: 39-2-2390220791 Fax/E-mail: 39-2-2367874 ] [2 Person in-charge: BombardieriE. Dr. (Title/Position) Director of Nuclear Medicine Department Other senior staff: F. Crippa; Pascali;C. DeciseD. A. Bogni; V. De Sanctis; C. Chiesa [3] Type of cyclotron: Positive Ion Manufacturer: Scanditronix Model: MC17E Year: (i) of installation: 1995 (ii) of any major reconstruction: 1995 ] [4 Particle beams available: 'H ZB 'He *He Dual Beams Beam energies/Range 77.2 8.6 (MeV) Typical currentt in s 50 50 (uA) Employet ex d (uA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 5 Hours per week machine maintenance: 5 Additional application cyclotrone th f so : Our PET/Cyclotron facility is totally devoted to clinical research diagnosticand activity fieldthe in of oncology Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 153 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch ie "F H2 O (96%) 77 4 per week enriched water recovered [6] Radionuclides planne producee b o dneat e th rn d i future : "c [7] Major radiopharmaceuticals produced: F-FDG F-Fluoride supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 4 * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . [10ra reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experience?r sfo Yes 154 ITALY ITA-4 [1] Institute: Consiglio Nazionale delle Ricerche Postal Address: Institute Pascale (CNR) ViaSemmolaM. 1-80131 Napoli Telephone: 39-81-5903528/527 Fax/E-mail: 39-81-5465797 [2] Person in-charge: Prof. Marco Salvatore (Title/Position) Other senior staff: Mariarosaria Panico; Gian Franco Antonello Green [3] Type of cyclotron: PositiveIon Manufacturer: Scanditronix Model: MC17 Year: (i) of installation: 1991 (li) of any major reconstruction: [4] Particle beams available: *H H * , - :? JHe 4He Dual Beams Beam energies/Range 17 5.5 (MeV) Typical currentt in s 75 50 (HA) Employet ex d 50 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 40 Hour weer spe k employe radionuclidn di e production: 15 Hours per week machine maintenance: 25 Additional application cyclotrone th f so : Diagnostic Radiotherapy/Activation Analysis/Radiobiology/Physics: Activation Analysis/Radiobiology Others: 155 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 (99.9999%) 18 8 per week I0 "N H2 0 3 2 per week "F S H2' O (96%) 50 week4per enriched water recovered «F Neon + 0.3% F2 "F-F2 [6] Radionuclides planned to be produced in the near future: I5 5 OforH2 0 11 "CHCfor 3I [7] Major radiopharmaceuticals produced: F-Fluoride 'F-FDG N-Ammonia C-Acetate [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 156 ITALY ITA-5 [1] Institute: Universita di Padova Postal Address: Medicina Nucleare Centra- PET Ospedaliero Castelfranco Veneto Via Ospedale18 No. 1-31033 Padova Telephone: 39-42-3732435 Fax/E-mail: 39-42-3732426 [2] Person in-charge: Prof. Giorgio Ferlin (Title/Position) Other senior staff: AlbertoFim [3 ] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDSI12 installationf Yearo ) (i : : 1994 (ii) of any major reconstruction: [4] Particle beams available: ITI ; 4He , *He Dual Beams JUl i 'ta f.x iintert^t , H '" ]$ p : ^SBK;,*, Beam JO - 8.5 energies/Range (MeV) Typical currents int 100 (uA) Employet ex d 20-30 (uA) Hours per week machine is in operation (excluding maintenance): « 75 Hours per week employed in radionuclide production: « 7 3 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 157 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GSBq)per batch "C "N+02 1 per month "N ~ 7 week8-10per n H^O + ethanol o I3N n ru r ~7pe 10 run per month 18f? a H2' O > 96% -22 5 x week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: \F-FDG 'N-Ammonia C-Acetate O Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511 KeVSPET 7 arriving * Gamma camera 1 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 7 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 158 ITALY 1TA-6 [1] Institute: CNR Insitute of Clinical Physiology Postal Address: Consiglio Nazionale delle Ricerche (CNR) Via Savi n. 8 1-56126 Pisa Telephone: 39-50-583254 Fax/E-mail: 39-50-553461; salvador@po. ifc.pi. cnr. it [2] Person in-charge: Piero SalvadoriA. (Title/Position) Head of Cyclotron and Radiopharmaceutical Chemistry Department Other senior staff: Luca;Di Petroni;L. D. RivaA. S. Antongiovanni; Cantini;A. PollM. [3] Type of cyclotron: NegativeIon Manufacturer: GE Model: PETTrace installationf Yearo ) (i : : 1996 majoy an (ii f r )o reconstruction : [4] Particle beams available: ; .% , H ' Beam energies/Range 16.4 8.5 (MeV) Typical currents int 75 max 60 max (uA) Employed ext 35 40 (uA) Hour weer spe k machin operatiom s ei n (excluding maintenance): 40 Hour weer spe k employe radionuclidn di e production: 30 Hours per week machine maintenance: 5 Additional applications of the cyclotron: Targetry (new targets for radionuclide production) Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Dosimetry (irradiation of new dosimetric material) 159 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C ^N2 + 0.5%O2 10 week5per radiopharmaceutical development "N H2'°0 3.7 8-12 per week n !0 o "N+ 02 2 3.7 week8per 4 administrationsper patient [6] Radionuclides planned to be produced in the near future: 124 I 123, 64Cu [1] Major radiopharmaceuticals produced: T-FDG N-Ammonia 'O-Water supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? 3 Centres upon request or monthly starting fall 1997 medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . ra [10 reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 160 JAPAN JPN-1 [1] Institute: National Institute Longevityfor Sciences Postal Address: Gengo, Morioka,Obu Aichi474 Telephone: 81-562-462311 Fax/E-mail: 81-562-445651; [email protected] [2] Person in-charge: Dr. Kengo Ito (Title/Position) Other senior staff: Kentaro Hatano; Takashi Kato [3] Typ cyclotronf eo : Negative Ion Acceleration A VF Cyclotron Manufacturer: Sumitomo Heavy Industries Model: HM-18 installationf Yearo ) (i : : 1995 (ii) of any major reconstruction: [4] Particle beams available: , •ftp»IT;. ••.->••«^£ 5'^fiH *'-*;. 1He : iHe Dual Beams Beam energies/Range 75 9 (MeV) Typical currentt in s 50 (UA) Employet dex -75 -25 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 5-6 Hour weer spe k employe radionuclidn di e production: 5-6 Hour weer spe k machine maintenance: I Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 161 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 53 3 per week "0 N2+23%Co 0.3 GBq/minx 2 per week 5-10min "F IS H2 O (98%) 9 1 per week enriched water recovery >*F Ne + 0.3%F2 12 week1per [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: F-FDG 'F-FDOPA supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET / * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomograph1 y (PET) engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 162 JAPAN JPN-2 [1] Institute: Research Institute for Brain and Blood Vessels Akita Postal Address: 6-10 Senshu-Kubota-machi Akita City Telephone: 81-188-330115 Fax/E-mail: 81-188-332104 [2] Person in-charge: Kazuhiro Takahashi; [email protected] (Title/Position) Other senior staff: [3] Typ cyclotronf eo : Baby Cyclotron Manufacturer: Japan Steel Works Model: BC-168 installationf Yearo ) (i : : 1983 majoy an (ii f r )o reconstruction : [4] Particle beams available: H * -,_• 2H 'He 'He Dual Beams Beam energies/Range 16 8 (MeV) Typical currents int 40 30 (HA) Employed ext (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 16 Hours per week employed in radionuclide production: 10 Hours per week machine maintenance: 2 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 163 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N3 week2per l> 0 "N2 week20per M «F Ne 1 per week ] [6 Radionuclides planne producee b o neade t th rn di future : 18O (p, n) I8F [7] Major radiopharmaceuticals produced: 18F-FDG "C-Methionine, "C-NMSP, "C-3NMPB supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 164 JAPAN JPN-3 [1] Institute: National Institute of Radiological Sciences Postal Address: Division of Advanced Technology for Medical Imaging Anagawa 4-9-1, Inage-ku CMba-shi 263 Telephone: 81-43-2512111 Fax/E-mail: 81-43-2876146 [2] Person in-charge: Kazutoshi Suzuki (Title/Position) Head Other senior staff: Toshiaki Irie; Kiyoshi Fukushi Terushi Haradahira ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: Sumitomo Heavy Industries Model: HM-18 Year: (i) of installation: 1994 (ii) of any major reconstruction: [4] Particle beams available: 'H * *a jHe «He Dual Beams Beam energies/Range 18 10 (MeV) Typical currentt in s 10 10 (UA) Employet ex d 20 (UA) Hours per week machine is in operation (excluding maintenance): 37 Hour weer spe k employe radionuclidn di e production: 20 Hour weer spe k machine maintenance: 6 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 165 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (G§«j)per batch "C Ni 10-40 ~ 20 per week receptor ligand "TV H2O 3-10 10 -12 per "NH3, labelling n week o N2(+O20.01%) 3-10 1 per week H2"0 ISp e H2' O (20%,5%) 1-10 2 per week enriched water recovery [6] Radionuclides planned to be produced in the near future: f8s~\O (p,/ n)\ ^5 Fj-> [7] Major radiopharmaceuticals produced: 18F-FDG C-Methionine' "C-NMSP, "C-SCH23390, "C-15Ro-1788 N-Ammonia O-Water supplu yo o yD [8radionuclides/radiopharmaceurical] otheo st r institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 3 engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurementss Ye ? b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 166 JAPAN JPN-4 [1] Institute: National Institute of Radiological Sciences Postal Address: Division of Advanced Technology for Medical Imaging Anagawa 4-9-1, Inage-ku Chiba-shi263 Telephone: 81-43-2512111 Fax/E-mail: 81-43-2876146 [2] Person in-charge: Kazutoshi Suzuki (Title/Position) Head Other senior staff: Toshiaki Irie; Kiyoshi Fukushi Terushi Haradahira [3] Type of cyclotron: A VF multi-particle Manufacturer: Thomson CSF Model: AVF-930 Year: (i) of installation: 1973 majoy an (ii f r)o reconstruction: [4] Particle beams available: H * ..'* ; 7* !*EL *He *He Dual Beams Beam energies/Range 90 55 145 no (MeV) Typical currents int (MA) Employed ext 5 20 2 10 (UA) Hours per week machine is in operation (excluding maintenance): 35 Hour r weespe k employe radionuclidn di e production: 10 Hour weer spe k machine maintenance: 8 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 167 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h U C N3 10-40 ~ 20 per week receptor ligand U N H2O 3-10 10 ~ 12 per week "NHi, labelling "0 N2(+O20.01%) 3-10 ' week1per H2"0 IS-r, S r (20%,H^O 5%) 1-10 2 per week enriched H2' O recovery a KK " 'Ar 0.5-1 weekper 2-3 ""'Ar (p. 3n) "Fe "Mn 0.1-0.2 3}Mn (p.4n) USj r u Nal, *^* [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: "C-Methionine, "C-NMSP, ^'C-lSRo-1788, "C-SCH23390 I5O- Water 52Fe-citrate 123I-Hippuric acid, 123I-Adsterol 18F-FDG N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? siten Ifo , indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 168 JAPAN JPN-5 ] [1 Institute: Daiichi Radioisotope Laboratories, Ltd. Postal Address: 453-1 Shimookura Matsuo-machi Sanbu-gun Chiba 289-15 Telephone: 81-479-864721 Fax/E-mail: 81-479-863642 [2] Person in-charge: Mr. Takehiro Okuda (Title/Position) Manager, Cyclotron Engineering Section Other senior staff: Yasuharu Sato [3] Type of cyclotron: FFAG Manufacturer: Scanditronix Model: MC-40 installationf Yearo ) (i : : 1984 (ii) of any major reconstruction: [4] Particle beams available: 1H *H "He 'He Dual Beams Beam energies/Range 30 (MeV) Typical currentt in s 180 (MA) Employed ext (uA) Hours per week machine is in operation (excluding maintenance): 720 Hour weer spe k employe radionuclidn di e production: 120 Hours per week machine maintenance: 8 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 169 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch zu'Pb /("77 (100%) -7000 10 per week enriched MiTl recovery [6] Radionuclides planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: 201Tl - Thallium Chloride supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? siten Ifo , indicate imaging devices available number *511 KeVSPET * Gamma camera Singl* e Photon Tomograph7 y (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 170 JAPAN JPN-6 ] [1 Institute: Daiichi Radioisotope Laboratories, Ltd. Postal Address: 453-1 Shimookura Matsuo-machi Sanbu-gun Chiba 289-15 Telephone: 81-479-864721 Fax/E-mail: 81-479-863642 [2] Person in-charge: Mr. Takehiro Okuda (Title/Position) Manager, Cyclotron Engineering Section Other senior staff: Yasuharu Sato ] [3 Typ cyclotronf eo : AVF Manufacturer: IBA Model: Cyclone30 installationf Yearo ) (i : : 1991 (ii) of any major reconstruction: [4] Particle beams available: 'H *R JHe *He Dual Beams Beam energies/Range 30 yes (MeV) Typical currents int 200 350 (HA) Employet ex d (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 120 Hours per week employed in radionuclide production: 120 Hours per week machine maintenance: 8 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 171 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) frequency Comments Produced (enrichment) per batch 6/Ga MZ« (100%) -1000 weekper 2 enriched Zn recovery Uil U4Xe (100%) -100 5 per week enriched Xe recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: (57|Ga - Gallium citrate 123 / -MYOMIBG' [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) engageu yo e nuclean di Ar r. reactio[10a ] n cross-section measurementso N ? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 172 JAPAN JPN-7 [1] Institute: Nihon Medi-Physics Co. Ltd. Chiba Facility Postal Address: 3-1 Kitasode, Sodegaura City Chiba Pref., 299-02 Telephone: 81-438-634771 Fax/E-mail: 81-438-633306 [2] Person in-charge: Toshio Iguti (Title/Position) Manager of Technical Section 1 Other senior staff: Yasuharu Sato [3] Type of cyclotron: AVF Manufacturer: Sumitomo Heavy Industries, Ltd. Model: 480P Year: (i) of installation: 1985 majoy an f r(iio reconstruction) : [4] Particle beams available: A H & * ; V *He *He Dual Beams Beam energies/Range 30 (MeV) Typical currents int 200 (uA) Employed ext 80 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 110 Hour weer spe k employe radionuclidn di e production: 105 Hours per week machine maintenance: 30 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 173 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch te >«F H, O (97%) 750 (EOB) 7 per week °'Ga °*Zn (97%) 500 (EOB) weekper 2-3 s'Rb *'Kr (99%) 40 (EOB) week1per Uil U4Xe (99%) 15 (EOS) 1-2weekper [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: Ga-citrate [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Hospitals in Japan, everyday [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 7 * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 174 JAPAN JPN-8 [1] Institute: Nihon Medi-Physics Co. Ltd. Chiba Facility Postal Address: Kitasode,3-1 Sodegaura City Chiba Pref., 299-02 Telephone: 81-438-634771 Fax/E-mail: 81-438-633306 [2] Person in-charge: Toshio Iguti (Title/Position) Manager Technicalof Section1 Other senior staff: [3 ] Typ cyclotronf eo : AVF Manufacturer: Sumitomo Heavy Industries, Ltd. Model: 750 PV installationf Yearo ) (i : : 1986 (ii) of any major reconstruction: ] [4 Particle beams available: *H *H 'He iHe Dual Beams Beam energies/Range 25-70 (MeV) Typical currentt in s 200 (MA) Employet dex 100 at 25 MeV (UA) MeV 70 Oat 5 Hour weer spe k machin operation i s ei n (excluding maintenance)0 11 : Hours per week employed in radionuclide production: 705 Hours per week machine maintenance: 30 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 175 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch •« S F H2' O (97%) (BOB)0 75 week7per e!Rb a'Kr (99%) (EOB)40 week1per '"I '"Xe (99%) (EOS)15 1-2weekper «"Tl ""Tl (96%) 300 (EOS) weekper 2 [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Hospitals in Japan, everyday medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? siten o f , I indicate imaging devices available number *511KeVSPET 7 Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . [10r a reactio] n cross-section measurementso N ? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 176 JAPAN JPN-9 [1] Institute: Kyushu University Postal Address: Department of Radiology Faculty of Medicine Maidashi 3-1-1 Fukuoka 812-82 Telephone: 81-92-6425788 Fax/E-mail: 81-92-6425833 [2] Person in-charge: Yasuo Kuwabara (Title/Position) Chief in Nuclear Medicine Section Other senior staff: Masayuki Sasaki; Isuyoshi Yoshida Toshimitsu Fukumura [3 ] Type of cyclotron: AVF Manufacturer: JSW Model: BC1710 installationf Yearo ) (i : : 1983 majoy an f r(ii o reconstruction) : ] [4 Particle beams available: XH *R *He *He Dual Beams Beam energies/Range 17 10 (MeV) Typical currentt in s 20-30 30 (uA) Employed ext (uA) Hours per week machine is in operation (excluding maintenance): Hour weer spe k employe radionuclidn di e production: 5 Hours per week machine maintenance: 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 111 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C 87 2 per week n "N o "N 60 1 per week "F MNe 25 1 per week ISp a H2' O (96.9) 37 week1per ] [6 Radionuclides planne producee b o neade t th rn d i future : [7] Major radiopharmaceuticals produced: 15O-Water, !5O-Oxygen, '5O-CarbonMonoxide, '5O-Carbon Dioxide "C-Methionine, '' C-Raclopride, "C-NMPB 18F-FDG, !8F-DOPA supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomographs Ye y (PET) engageu yo e nuclean di Ar r[10. a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 178 JAPAN JPN-10 [1] Institute: Fukui Medical University Postal Address: Biomedical Imaging Research Centre 23 Shimoaizuki, Matsuoka-cho Fukui 910-11 Telephone: SI-776-613111 Fax/E-mail: 81-776-618137; [email protected] [2] Person in-charge: Prof. Yoshiharu Yonekura (Title/Position) Other senior staff: Norihiro Sadato; Akira Yokoyama Yasuhisa Fujibayashi [3] Type of cyclotron: Superconducting, Negative Ion Manufacturer: Oxford Model: OSCAR5 Year: (i) of installation: 1994 (ii) of any major reconstruction: [4] Particle beams available: *H V.'rf|l *H *He *He Dual Beams Beam energies/Range 12 (MeV) Typical currents int ("A) Employed ext 50 (uA) Hours per week machine is in operation (excluding maintenance): 20 Hours per week employed in radionuclide production: 15 Hour weer spe k machine maintenance: 3 Additional applications of the cyclotron: Radiotherapy/Activation Analy sis/Radiobiology/Phy sics: Others: 179 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h 14 "C N2 (95%) 15 month1per "N Hi'°O (100%) 6 1 per week n h o N2 (95%) 2.6 week1per >«F a H2' O (50%) 37 week2per enriched water recovery ] [6 Radionuclides planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: 18'F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No yesf I , whic oftenw h ho one ?d san medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera 2 Singl* e Photon Tomography (SPET) I * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 180 JAPAN JPN-11 [1] Institute: Japan Atomic Energy Research Institute (JAERI) Postal Address: 1233 Watanuki, Takasaki Gunma 370-12 Telephone: 81-273-46-9677 Fax/E-mail: 81-273-469690 ] [2 Person in-charge: T.SekineDr. (Title/Position) Principal Scientist Other senior staff: Noriko Ishikoka WatanabeS. ] [3 Typ cyclotronf eo : AVFCyclotron, K-110 Manufacturer: Sumitomo Heavy Industries Model: CGR-MeV930 installationf Yearo ) (i : : 1990 (ii) of any major reconstruction: ] [4 Particle beams available: 'H *H *He *He Dual Beams Beam energies/Range 10-90 10-50 100 20 ~ (MeV) Typical currents int UA Employet ex d 5 20 5 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 92 Hours per week employed in radionuclide production: 5 Hour weer spe k machine maintenance: 5 Additional application cyclotrone th f so : Materials science space nuclearfor and fusion Production of functional materials Biotechnology, Radiation chemistry Radiotherapy/ Acti vation Analy sis/Radiobiology/Phy sics: Radiobiology, Physics Others: Radionuclides used studiesfor of plant physiology 181 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N, MBq 37 I per week JJ tl N H2 O lOOMBq I per week '"O depleted water 18 p S H2' O (99.3%) MBq 600 1 per month IS p H20 lOOMBq 2 per month uvCe occasional 'y°Re lst>W(97%) MBq 7 3 year3per enriched lst>W recovery [6] Radionuclides planne producee b o dneat e th rn d i future : 48 V. 62Znf2Cu [7] Major radiopharmaceuticals produced: supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, whic oftenw h ho one ?d san Possible,Re once suppliedand we Ce [9] Is medical research/diagnosis carried out on site/off site? No siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 182 JAPAN JPN-12 [1] Institute: Gunma University School of Medicine Postal Address: 39-15 Showa-machi 3-chome Maebashi-shi Gunma-ken 371 Telephone: 81-27-2208661 Fax/E-mail: [2] Person in-charge: Prof. Keigo Endo (Title/Position) Chairman Other senior staff: Tomio Inoue; Kunio Matsubara Katsumi Tomiyoshi [3] Typ cyclotronf eo : Baby Cyclotron Manufacturer: Japan Steel Works Ltd. Model: BC1700 Year: (i) of installation: 1983 (ii) of any major reconstruction: [4] Particle beams available: J *H ,, *R He *He Dual Beams Beam energies/Range 18 10 (MeV) Typical currents int 30 30 (uA) Employed ext (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 15 Hours per week employed in radionuclide production: 2 Hours per week machine maintenance: 3 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 183 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N2 2 weekper 2 UN '"0 4 weekper 2 '=0 I4N 10 week2per >*p ia H2 O (50%) 4 week3per '«F Ne/F2 2 week2per [61 Radionuclides planned to be produced in the near future: 186Re,!86W(p,n)186Re [7] Major radiopharmaceuticals produced: 18F-FDG, 18F-oMT N-Ammonia 15O-Water nC-Met [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) 7 * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 184 JAPAN JPN-13 [1] Institute: Nikko Memorial Hospital Postal Address: 1-5-13 Shintomicho, Muroran Hokkaido051 Telephone: 81-143-241331 Fax/E-mail: 81-143-241064 [2] Person m-charge: Masahiro Shinohara (Title/Position) Department of Radiology Other senior staff: Hideki Itoh; Hiroyuki Nozaki; Masashi Yamaguchi [3] Type of cyclotron: Deep Valley Fixed Energy Proton Cyclotron Manufacturer: CTI Model: 111 RDS installationf Yearo ) (i : : February, 1998 (planned) (ii) of any major reconstruction: [4] Particle beams available: 'H *H *He *He Dual Beams Beam energies/Range 11 (MeV) Typical currents int 40 (HA) Employet ex d 40 (ttA) Hours per week machine is in operation (excluding maintenance): 48 Planned Installation underway Hours per week employed in radionuclide production: 48 Hours per week machine maintenance: 2 Additional applications of the cyclotron: Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: The installation of the RDS 111 cyclotron shall begin in December, 1997, and PET diagnosis is expected to start in February, 1998. 185 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "N H2O 15 week1per "0 "N2 (99.999%) 7.4 week3per a "F H2' O (98%) 12 4 per week ] [6 Radionuclides planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: isT-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which oftenw ho one ?d san medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections No Thick target yields No s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 186 JAPAN JPN-14 [1] Institute: Nihon Medi-Physics Ltd.Co. Hyogo Facility Postal Address: Techno9-1 Park, Sanda City Hyogo Pref., 669-13 Telephone: 81-795-684771 Fax/E-mail: 81-795-683071 [2] Person in-charge: Shigeaki Kataoka (Title/Position) Manager of Technical Section 1 Other senior staff: [3 ] Type of cyclotron: Fixed field, fixed frequency, accelerating If ions Manufacturer: IBA s.a Model: Cyclone 30 • installationf Yearo ) (i : : 1990 majoy an (iif ro )reconstruction : ] [4 Particle beams available: *H : /H *He *He Dual Beams Beam energies/Range 16-30 (MeV) Typical currents int (uA) Employed ext 330 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 725 Hour weer spe k employe radionuclidn di e production: 725 Hours per week machine maintenance: 72 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 187 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequeucy Comments Produced (enrichment) batcr pe h *'Rb "Kr (99%) 80 (EOB) 1 per week '"In l"Cd(97%) (EOB)180 1-2 per week usl U4Xe (99%) 750 (EOS) 2-3weekper ""77 MiTl (97%) 300 (EOS) 2-3per week [6] Radionuclides planned to be produced in the near future: is [7] Major radiopharmaceuticals produced: 20!"na r 3I-IMP, 'I-BMIPP [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes yesf I , whic oftenw h ho one ?d san Hospitals Japan,in everyday [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurementso N ? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 188 JAPAN JPN-15 [1] Institute: Nihon Medi-Physics Ltd.Co. Hyogo Facility Postal Address: 9-1 Techno Park, Sanda City Hyogo Pref., 669-13 Telephone: 81-795-684771 Fax/E-mail: 81-795-683071 [2] Person in-charge: ShigeaJd Kataoka (Title/Position) Manager Technicalof SectionI Other senior staff: [3] Type of cyclotron: Fixed field, fixed frequency, accelerating ionsIT Manufacturer: IBA s.a Model: Cyclone 30 installationf Yearo ) (i : : 1992 (ii) of any major reconstruction: ] [4 Particle beams available: *H I; 3B *He "He Dual Beams - :,p•IV jT'1"' Beam energies/Range 15-30 (MeV) Typical currentt m s (MA) Employet ex d 360 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 125 Hour weer spe k employe radionuclidn di e production: 125 Hour weer spe k machine maintenance: 12 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 189 [5] Radionuclides produced: Radionoclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h *'Rb S2Kr (99%) 80 (BOB) 1 per week '"In luCd(97%) (EOB)180 1 per 2 weeks '"I U4Xe (99%) 750 (EOS) 2-3 per week JUI J.T /yJ77 (97%) 300 (EOS) 2-3 per week [6] Radionuclides planne producee b o neade t th rn di future : is [7] Major radiopharmaceuticals produced: 201 TICl 123I-IMP, 123I-BMIPP [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Hospitals in Japan, everyday [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nucleadn Ar i [10. r a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r dat?yo o ad Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 190 JAPAN JPN-16 [1] Institute: Hyogo Institute for Aging Brain & Cognitive Postal Address: Disorders 520 Saisho-ko, Himeji Hyogo670 Telephone: 81-792-955511 Fax/E-mail: 81-792-958199; [email protected] [2] Person in-charge: Dr. Kazunari Ishii (Title/Position) Director of PET Section Other senior staff: Masahiro Susaki Toru Kida [3] Type of cyclotron: Superconducting Negative CyclotronIon Manufacturer: Oxford Model: OSCAR-2 installationf Year:o ) (i : 1992 majoy an (iif r o )reconstruction : [4] Particle beams available: *H *H "He "He Dual Beams Beam energies/Range 12 (MeV) Typical currentt in s 50 (UA) Employet ex d 50 (UA) Hour weer spe k machin operation i s ei n (excluding maintenance)4 ~ 3 : Hours per week employed in radionuclide production: 3 Hours per week machine maintenance: 1 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 191 [5] Radionuclides produced: Radiouuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 14 "C N2 (99.9999%) 37 2 per week addition2 1%O n I3 o N2 (99.8%) 56 20 per week 15% CO2 addition ISp 1S H2 0 (50%) 15 2 per week enriched H2'*O recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: I8F-FDG 15O-Carbon Monoxide, 15O-Water, '5O-Carbon Dioxide 15O-Oxygen [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san medicas I [9] l research/diagnosi siten O s carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . [10ra reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sYe sections Thico kN target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 192 JAPAN JPN-17 [1] Institute: National Research Institute for Metals Postal Address: 1-2-1 Sengen, Tsukuba Ibaraki 305 Telephone: 81-298-592014 Fax/E-mail: 81-298-592014; [email protected] [2] Person in-charge: Johsei Nagakawa (Title/Position) Group Leader Other senior staff: Norikazu Yamamoto; Yoshiharu Murase; Toshimitsu Fukuzawa ] [3 Typ cyclotronf eo : A VF Cyclotron (fixed energy) Manufacturer: The Japan Steel Works Ltd. Model: BC1710 Year: (i) of installation: 1986 (ii) of any major reconstruction: ] [4 Particle beams available: '? *R *He "He Dual Beams Beam energies/Range 4.25/17 10 26 20 (MeV) Typical currentt in s 50 50 30 30 (MA) Employed ext 30 30 15 15 (uA) (max.50) (max. 50) (max. 20) (max.20) Hours per week machine is in operation (excluding maintenance): 50 Hours per week employed in radionuclide production: 20 Hour weer spe k machine maintenance: 3 Additional application cyclotrone th f so : It is dedicated only to the materials science research (in situ and post-irradiation measurements, etc.) No RIproduction in intended Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: The cyclotron and 2 target chambers are all in a single room 193 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b neao de t th rn d i future : [7] Major radiopharmaceuticals produced: supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? No If on site, indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 194 JAPAN JPN-18 [1] Institute: Kanazawa Cardiovascular Hospital Postal Address: Tanaka,16 Ha Kanazawa Ishikawa Telephone: 81-76-2538000 Fax/E-mail: 8]-76-25 30008 [2] Person in-charge: Name providednot (Title/Position) Other senior staff: [3] Type of cyclotron: Baby cyclotron for medical use Manufacturer: The Japan Steel Works Ltd. Model: BC1710 installationf Yearo ) (i : : 1991 (ii) of any major reconstruction: ] [4 Particle beams available: "H t;-!. ^ *He «He Dual Beams t J Beam energies/Range 17 10 (MeV) Typical currentt in s (HA) Employed ext 60 60 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 2 ~ : Hours per week employed in radionuclide production: ~ 4 Hours per week machine maintenance: ~ 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: PET 195 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 (100%) 3.7 3 per week UN 3.7 week1per n H2O o N2 (98%) 3.7 week3per «F Ne (99.5%) 7.4 4 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: isT-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Arengageu eyo nuclean di r reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 196 JAPAN JPN-19 [1] Institute: Nishina Memorial Cyclotron Centre Postal Address: 348-58 Tomegamori, Takizawa Iwate 020-01 Telephone: 81-19-6886071 Fax/E-mail: 81-19-6886072 ] [2 Person in-charge: S. Suzuki (Title/Position) Director Other senior staff: S. Futatsugawa; S. Hatakeyama SeraK. [3] Type cyclotronf o : AVF Manufacturer: Shimadzu Model: MCY1750 Year: (i) of installation: 1989 (ii) of any major reconstruction: ] [4 Particle beams available: *H *H *He "He Dual Beams Beam energies/Range 16.9 8.3 (MeV) Typical currentt in s (uA) Employed ext 30 30 (UA) Hour weer spe k machin operation i s ei n (excluding maintenance): 40 Hours per week employed in radionuclide production: 6 Hour weer spe k machine maintenance: 8 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Proton Induced X-ray Emission (PIXE) 197 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment- ' ) " per batch "C N3 37 2 per week '=0 N2 (O2:0.5%) GBq/min3 week6per IBp (FNe 2:0.4%) 14.5 week1per [6] Radionuclides planned to be produced in the near future: /JN [7] Major radiopharmaceuticals produced: 15O-Oxygen, '5O-Carbon Dioxide, '5O-Carbon Monoxiode, 15O-Water I8F-FDG supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) * Positron Emission Tomograph/ y (PET) engageu yo e nuclean dAr i . ra [10reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 198 JAPAN JPN-20 ] [1 Institute: Nishijin Hospital Postal Address: 1035 Mizomae-cho, Kamigyo-ku Kyoto 602 Telephone: Fax/E-mail: 81-75-4615514 [2] Person in-charge: Takahiro Kanatsuna (Title/Position) President Other senior staff: Takehiko Yagyu; Hitoshi Horii Kazuo Wakita; Ryou Fujii [3] Type of cyclotron: Positive Ion Manufacturer: The Japan Steel Works Ltd. Model: BC1710 installationf Yearo ) (i : : 1985 majoy an (ii f r)o reconstruction: [4] Particle beams available: *H *H "He "He Dual Beams Beam energies/Range 17 10 (MeV) Typical currents int 70-80 extracting ("A) efficiency: (60 65%)- Employet ex d 10-50 (uA) Hours per week machine is in operation (excluding maintenance): 6-10 Hours per week employed in radionuclide production: 6-10 Hour weer spe k machine maintenance: 4-8 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 199 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 (99.999%0 15 1-2 per week continuous 15 !S (CO O2) 2.5% CO2+N2 6 4~6 per week inhalation 0.4 min 15 in GBq •* F 0.15~0.5%F2/Ne 10 1~2 per week 13 n n O ("02, C O) 0.5% O2+N2 11 weekper 4-6 O2 0.6 GBq per batch [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: !5 !5 O~Oxygen,!5 O-Carbon Dioxide,O-Cabon Monoxide 4-18F Fluoro-borono-phenylanine (18FBPA). I8F-DOPA 1-"C -Butyryl-2-polmitoyl glycerol ("C-DAG) I8F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Diagnosis, on site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph7 y (PET) engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 200 JAPAN JPN-21 ] [1 Institute: Kyoto University Hospital Postal Address: Kawahara-cho-54, Shogoin, Sakyo-ku Kyoto 606-01 Telephone: 81-75-7534567 Fax/E-mail: 81-75-7513306; [email protected] [2] Person in-charge: Yasuhiro Magata (Title/Position) Other senior staff: Haruhiro Kitano [3] Typ cyclotronf eo : AVF Manufacturer: Sumitomo Heavy Industry Model: Cypris 325 installationf Yearo ) (i : : 1982 (ii) of any major reconstruction: 1997 - change of electronic circuit [4] Particle beams available: IXT l t •:,. „.spastf - *He "He Dual Beams £t* * *. „ * "%*-i> ••'*&**« "•"-' ,/*v * Beam energies/Range 75 8 (MeV) Typical currents int (HA) Employed ext 35 (HA) Hours per week machine is in operation (excluding maintenance): 20 Hours per week employed in radionuclide production: 20 2 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 201 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N2 25 weekper 2 n"N H2O 10 week1per o N 4 2 per week '«F A S nfo 15 3 per week enriched H2' O recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: "F-FDG N-Ammonia !5O-Water, !SO-Oxygen, 11C-Acetate [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which oftenw ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 202 JAPAN JPN-22 [1] Institute: Nagoya City Rehabilitation Centre Postal Address: Mikanyama,1-2 Yatomi-cho Mizuho-ku Nagoya 467 Telephone: 81-52-8354573 Fax/E-mail: [2] Person in-charge: Akihiko lida (Title/Position) Director Other senior staff: Noriyuki Kato Katsumi Araki [3] Type of cyclotron: AVF Cyclotron Manufacturer: Sumitomo Heavy Industries Model: Cypris370 installationf Yearo ) (i : : 1989 majoy an (iif ro ) reconstruction: [4] Particle beams available: *H vrv*H, *He "He Dual Beams Beam energies/Range 18 JO (MeV) Typical currentt in s -40 -60 (HA) (Deflector) Employed ext -20 25 (uA) Hours per week machine is in operation (excluding maintenance): -10 Hours per week employed in radionuclide production: -6 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 203 ] [5 Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 -30 ~ 1 per week -10 1-2 per week n"0 (2.5%)2 CO N+ 2 o N2 + O2 (0.5%) -10 1-2 per week ISp Ne F+ 2 (5%) -15 ~ 1 per week a >*F H2' O (96%) -30 weekper 0-1 [6] Radionuclides planned to be produced in the near future: 13'N [7] Major radiopharmaceuticals produced: ls !5 O-Oxygen,'5 O-Carbon Monoxie,O-Carbon Dioxide I8F-FDG supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 204 JAPAN JPN-23 [I] Institute: Nagoya University School of Medicine Postal Address: Department of Radiology 65 Tsurumaicho, Showa-ku Nagoya City466 Telephone: 81-52-7442328 Fax/E-mail: 81-52-7442335 ] [2 Person in-charge: Masanori Tadokoro (Title/Position) Other senior staff: Takeo Ishigakt Masanari Nishino [3] Type of cyclotron: Baby Cyclotron Manufacturer: Japan Steel Works Model: BC2211 installationf Yearo ) (i : : 1989 majoy an f (iiro )reconstruction : ] [4 Particle beams available: "H •. . |H *He 'He Dual Beams • * 1 Beam energies/Range 22 11 (MeV) Typical currentt in s 100 100 (HA) Employed ext 60 60 (HA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 6 Hour weer spe k machine maintenance: 3 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 205 [5] Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h n"C N2 100 month1per o N2 100 1 per week "F Ne 16 3 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG O- Water C-Methionine [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosi siten O s carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET 2 Gamm* a camera * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 206 JAPAN JPN-24 [1] Institute: Osaka City University Medical School Hospital Postal Address: 1-5-7 Asahi-machi, Abenoku Osaka City Telephone: 81-6-6452196 Fax/E-mail: 81-6-6460686 [2] Person in-charge: HironobiDr. Ochi (Title/Position) Other senior staff: [3] Type of cyclotron: Compact Superconducting, NegativeIon Manufacturer: Oxford Model: OSCAR SCC12P installationf Yearo ) (i : : 1992 (ii) of any major reconstruction: 1993 [4] Particle beams available: *H *H 'He "He Dual Beams Beam energies/Range 12 (MeV) Typical currentt in s 50 (uA) Employed ext 15-40 (UA) Hours per week machine is in operation (excluding maintenance): « 6 Hour weer spe k employe radionuclidn di 5 3- e production: Hours per week machine maintenance: 1 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 207 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h na "C 'N2 3500MBq 1 per month "N H2O 1500 MBq week1per "0 "N2 2000MBq week2per N enriched [6] Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: 18F-FDG 15 15 5 O-Water,I5 O-Oxygen,O-Carbon Dioxide, O-CarbonMonoxide' N-Ammonia -MethionineC [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san medicas I ] l[9 research/diagnosi siten O s carrie site/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thick target yields No s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 208 JAPAN JPN-25 [1] Institute: Institute for Biofunctional Research Postal Address: 5-7-1 Fujishiro-dai, Suita-shi Osaka565 Telephone: 81-6-8347000 Fax/E-mail: 81-6-8728761 ] [2 Person in-charge: Naoto Hashimoto (Title/Position) Director Other senior staff: Yuji Kuge Koji Tamura [3] Typ cyclotronf eo : AVF Manufacturer: Sumitomo Heavy Industries, Ltd. Model: 18 EM Year: (i) of installation: 1992 majoy an (ii f r) o reconstruction : [4] Particle beams available: *H ?H JHe "He Dual Beams J 1, 4«,;l , Beam energies/Range 18 10 (MeV) Typical currentt in s 15-20 10-15 (uA) Employed ext 25 max 20 max (MA) Hour weer spe k machin operation i s ei n (excluding maintenance): Hour weer spe k employe radionuclidn di e production: 8-10 Hours per week machine maintenance: 10 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 209 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C #2 40-50 1 per month n"N H2'°O+5mMEtOH 1.7 1 per 3 months o N O+ 2 2(0.4%) 7.5 (2-3) x (5-7) ISp IB (0.2%)2 F Ne + 5 1 per week F-F2 [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: >SF-FDG, ™F-Haloperidol "C-l- Octanoic acid, "C-NMSP, "C-Raclopride, "C-Nicergoline l5O-Water, nO-Oxygen, '5O-Carbon Dioxide, ls O-Carbon Monoxide N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? Research, on site Specific to animalPET studies siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean di Ar r[10. reactioa ] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction croso sN sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 210 JAPAN JPN-26 [1] Institute: National Cardiovascular Centre Postal Address: 5-7-1 Fujishirodai, Suita Osaka565 Telephone: 81-6-8335012 Fax/E-mail: 81-6-8727486 [2] Person in-charge: Yoshio Ishida (Title/Position) Director of Nuclear Medicine Other senior staff: Kohei Hayashida; Kazuki Fukuchi Yoshinori Miyake [3] Type of cyclotron: AVF Cyclotron Manufacturer: Sumitomo Heavy Industries Model: Cypris370 installationf Yearo ) (i : : 1989 (ii) of any major reconstruction: [4] Particle beams available: 4H *H 'He *He Dual Beams Beam energies/Range 18 10 (MeV) Typical currents int 15 15 (HA) Employet ex d 20 20 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 9 Hours per week employed in radionuclide production: 7 Hour weer spe k machine maintenance: 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analy sis/Radiobiology/Physics: Others: Positron Emission Tomography Clinicalfor Diagnosis 211 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C "N2 (99.9999%) 56 week2per "C02 n"N Deionization H2O 4.4 week5per "NO,n o "N(99.7%) 12 week2per o2 obtainedO flow irradiation n 2 n o I4N(99.7%) 12 2 per week c o obtained2 O flow irradiation 14 n "0 N(99.7%) 360 week1per H2 O obtained2 O flow irradiation n I4 o N(98%) 12 weekper 2 ^02 obtained CO2 flow irradiation ISp 'uNe (99.8%) 1.5 week1per ISF-FDG [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: I8F-FDG I5O-Water, I5O-Oxygen, '5O-Carbon Dioxide, '5O-Carbon Monoxide N-Ammonia 11C-Acetate supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera * Single Photon Tomography (SPET) 5 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thick target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 212 JAPAN JPN-27 [1] Institute: Hokkaido University Hospital Postal Address: N-15W-7Kita-ku Sapporo 060 Telephone: 81-71-7161161 (ext. 5823) Fax/E-mail: [2] Person in-charge: Nagara Tamaki (Title/Position) Professor Chairmanand Other senior staff: Chietsugu Kato; Toru Shiga [3] Type of cyclotron: decidedNot Manufacturer: Model: Year: (i) of installation: 1998 (ii) of any major reconstruction: ] [4 Particle beams available: *H *H *He "He Dual Beams Beam energies/Range (MeV) Typical currentt in s (HA) Employet ex d (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 213 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera Singl* e Photon Tomography (SPET) 4 Positro* n Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 214 JAPAN JPN-28 [1] Institute: Tohohu University, (CYRIC) Postal Address: Cyclotron and Radioisotope Center (CYRIC) Aramaki, Aoba-ku Sendai980-77 Telephone: 81-217-7798 Fax/E-mail: 81-263-5358; [email protected] [2] Person in-charge: Prof.Iwata;Ren Prof. TatsuoIdo (Title/Position) Other senior staff: [3] Type of cyclotron: A VF Multi-Particle Manufacturer: Sumitomo Heavy Industries Model: 680 AVF Year: (i) of installation: 1977 (ii) of any major reconstruction: [4] Particle beams available: IH r _ *H *Hc *He Dual Beams Beam 40 25 65 50 energies/Range (MeV) Typical currentt in s (uA) Employed ext 15 12 5 5 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 87- 96 Hour weer spe k employe radionuclidn di e production: 16 Hour weer spe k machine maintenance: 12 Additional applications of the cyclotron: Radiotherapy/ Activation Analysis/Radiobiology/Physics: Activation analysis,Physics Others: 215 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C Ni 30 1~3 per week "0 N2 -30 week2per ISp S H2' O (96%) 11 3-4 per week "Mz Al 0.2 MBq 1 per week ] [6 Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: 1SF-FDG, '*F-DOPA C-Methionine, C-Doxepin, C-Nemonapride !5O-Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 3 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 216 JAPAN JPN-29 [1] Institute: University of Tokyo Postal Address: Department of Radiology 7-3-1 Hongo Bunkyo-ku Tokyo113 Telephone: 81-3-38155411 ext. 5129 Fax/E-mail: 81-3-58008678 [2] Person in-charge: Johru Ontoke (Title/Position) Assistant Professor Other senior staff: Toshimitsu Momose ShinyaOku [3] Type of cyclotron: Positive Ion Manufacturer: Sumitomo Heavy Industries, Ltd. Model: Cypris 370 Year: (i) of installation: 1988 (ii) of any major reconstruction: [4] Particle beams available: 1H . - , ^He 4He Dual Beams • •v^ , *k ,' **• - Beam energies/Range 18 10 (MeV) Typical currents int 50 50 (uA) Employed ext (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 32 Hours per week employed in radionuclide production: 32 Hours per week machine maintenance: 8 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Phy sics: Others: 217 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 (99.9999) 2 weekper 2 "N H2O 2 weekper 2 "0 N2(B)+0.5%O2 4 2 per week ISp Ne(B) +5 % F2 2 weekper 2 [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: l3N-Ammonia >5O-Water, I5O-Oxygen, 15O-CarbonMonoxide, 15O-CarbonDioxide C-Methionine,' 1 C-N-Methylspiperone'' 18F-FDG, I8F-DOPA supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten o f , I indicate imaging devices available number *511 KeVSPET 1 * Gamma camera 1 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 218 JAPAN JPN-30 [I] Institute: Tokyo Metropolitan Institute of Gerontology Postal Address: 35-2 Sakaecho Itabashi Tokyo173 Telephone: 81-3-39643241 ext. 3503 Fax/E-mail: 81 -3-35794776; [email protected] [2] Person in-charge: Michio Senda (Title/Position) Head, Positron Medical Centre Other senior staff: Kiichi Ishiwata Hinako Toyama [3] Type of cyclotron: VF,A PositiveIon Manufacturer: Sumitomo Heavy Industries Model: Cypris 370 installationf Yearo ) (i : : 1990 majoy an f ro (iireconstruction) : [4] Particle beams available: '!,£ 'i&Tf- JHe "He Dual Beams 1H 4 |»IMsrtfr>s;'-t :s-, :,; * £»•< Beam energies/Range 18 10 24 18 (MeV) not routinely not routinely used used Typical currents int 30 10-25 (MA) Employed ext (uA) Hours per week machine is in operation (excluding maintenance): 24 Hours per week employed in radionuclide production: 24 Hours per week machine maintenance: 8 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 219 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Qn 2 (99.9999%)N 73 2 per daymin 20 nA, 30 o N2+O2 (O.5%) 3 GBq/min week1per JO MA "0 N2+CO2 (2.5%) 3 GBq/min week1per 10p.A "F H2*O (96%) 24 week1per fiA,min 15 20 " F Ne+F2 (5%) 30 2 per month 24 tiA, 120 min ] [6 Radionuclides planne producee b o dneat e th r dn i future : 13 \ T [7] Major radiopharmaceuticals produced: 5 15 H O O-Oxygen,'5 O-Carbon' Dioxide,O-Carbon Monoxide 2 C-Methionine, C-N-methylspiperone, C-Flumazenil I8F-FDG, I8F-DOPA [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 1 Singl* e Photon Tomography (SPET) Positro* n Emission Tomography (PET) 2 engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 220 JAPAN JPN-31 [1] Institute: National Centre of Neurology and Psychiatry Postal Address: 4-1-1 Ogawahigashi-cho, 4-Chome, Kodaira Tokyo 187 Telephone: 81-423-412711 Fax/E-mail: 81-423-446745 [2] Person in-charge: Hiroshi Matsuda (Title/Position) Director of Radiological Division Other senior staff: Yutaka Takayama; Satoru Horikoshi Kenichi Ogawa; Masato Kobayashi [3] Type of cyclotron: Superconducting Compact Manufacturer: Oxford Model: OSCAR, SCC12P Year: (i) of installation: 1997 (n) of any major reconstruction: ] [4 Particle beams available: 'H , *H "He *He Dual Beams Beam energies/Range 12 (MeV) Typical currents int (HA) Employet ex d 11.4 (uA) Hours per week machine is in operation (excluding maintenance): Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: 10 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 221 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "0 "N2 (97%)+ 18 continuous O2(1.5%) inhalation >« 1 F H2' O (50%) 20 1-2 per week enriched water recovery [6] Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: !8F-FDG 15O-Water, I5O-Oxygen, O-Carbon5 ' Dioxide, '5O-Carbon Monoxide [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? Research/ diagnosis, on site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 222 JAPAN PN-32 [1] Institute: International Medical Centre of Japan Postal Address: Radiology Department 1-21-1 Toyama, Shinjaku-ku Tokyo162 Telephone: 81-3-32026560 Fax/E-mail: 81-3-32026560; [email protected] ] [2 Person in-charge: ToshihikoDr. Hara (Title/Position) Chief, Nuclear Medicine Other senior staff: Noboru Kosaka [3] Typ cyclotronf eo : NegativeIon Manufacturer: Japan Steel Works Model: BC2010N Year: (i) of installation: 7995 majoy an (iif r o )reconstruction : [4] Particle beams available: 1H •>%. ; "He "He Dual Beams Beam energies/Range 20 10 yes (MeV) Typical currentt in s 33 11 (HA) Employed ext 30 10 (HA) Hours per week machine is in operation (excluding maintenance): 22 Hours per week employed in radionuclide production: 20 Hours per week machine maintenance: 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others. 223 [5] Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N3 14.8 10 per week "N H2O 3.7 2 per week "0 N2 + H2 3.7 week10per ISp S H2' O (> 95%) 7.4 4 per week [6] Radionuclides planned to be produced in the near future: 68Ge, [7] Major radiopharmaceuticals produced: F-FDG C-Choline O-Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) / engageu yo e nuclean dAr i r. [10a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 224 JAPAN JPN-33 [1] Institute: HIMEDIC Imaging Centre Lakeat Yamanaka Postal Address: 562-12 Yanagihara, Hirano Yamanakako-mura, Minamitsuru-gun Yamanashi 401-05 Telephone: 81-555-659135 Fax/E-mail: 81-555-203007 ] [2 Person in-charge: MichiruDr. Ide (Title/Position) Other senior staff: Akira Shotsu; Seiei Yasuda Wakou Takahashi; Shigeharu Takagi [3] Typ cyclotronf eo : AVF Cyclotron Manufacturer: Sumitomo Heavy Industries Ltd. Model: HM18 Year: (i) of installation: 1993 majoy an f r(ii o reconstruction) : ] [4 Particle beams available: L S ; *H *He "He Dual Beams \ -< " -, Beam energies/Range 18 70 (MeV) Typical currentt in s 10 (uA) Employed ext 50 (uA) Hours per week machine is in operation (excluding maintenance): 5 Hours per week employed in radionuclide production: 5 Hours per week machine maintenance: 4 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 225 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N, 5 2 per month "N H2'°0 16 4 per month 14 "0 N0.5%+ 2 2 O 13 1 per month "N2+2.0-2.5%CO2 >* S S F H2' 0 (80%) 16 monthper 5 enriched H2' O recovery ] [6 Radionuclides planne producee b neao de t th r n di future : [7] Major radiopharmaceuticals produced: F-FDG O-Water, I5O-Oxygen, '5 O-Carbon Dioxide, l5O-Carbon Monoxide N-Ammonia C-L-Methionine, C-N-Methyl-spiperone [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph3 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields No Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 226 KAZAKSTAN KAZ-1 [1] Institute: Institute of Nuclear Physics Postal Address: Almaty-480082 Telephone: 7-3272-690433 Fax/E-mail: 7-3272-631207; [email protected] [2] Person in-charge: Prof. Arzumanov Artyom (Title/Position) Head of Accelerator Laboratory Other senior staff: Sychikov Gennadi; Popov Yuri Batischev Viktor [3] Type of cyclotron: Variable Energy Isochronous Cyclotron K=50MeV Manufacturer: Efremov Institute in Leningrad Model: U150 Year: (i) of installation: 1965 majoy an f r o (iireconstruction) : 1972, conversion variableto energy isochronous mode of operation [4] Particle beams available: i -~ - [ ^B f:p,lHe;,,:;> 3Be j Dual Beams •<«• "v*> - • * ^, •J&r4 ;«!s,i.*jk,3« * (- Beam energies/Range 6-30 12-25 75.5 - 62 25-50 no (MeV) Typical currents int 200 200 100 150 (uA) Employet ex d 30 40 15 20 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 50 Hours per week employed in radionuclide production: 20 Hour weer spe k machine maintenance: 3 Additional application cyclotrone th f so : Nuclear Science Research, Radiation Material Science Research Radiotherapy/Activation Analysis/Radiobiology/Physics: Physics Others Typically cyclotronthe -was operated 5600 hours of beam targeton per year Now due to temporary financial difficulties beam time is reduced to 1500 hours per year 227 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 31 Co Ni 0.04 3 per year /y'77 (96%)™Tl 3.7 5 per year enriched™Tl recovery * Small* quantities of236KBq Pu, 237Pu, 238 alsoPuare produced [61 Radionuclides planned to be produced in the near future: , ^ ~ 57Co,~ Ga, Ca [I] Major radiopharmaceuticals produced: Thallium-201 supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st rs institutionsYe ? If yes, whic oftenw h ho one ?d san 20fTl-Thallous chloride times10 1994in times5 1995in 3 times in 1996 [9] Is medical research/diagnosis carried out on site/off site? Off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . ra [10reactio] n cross-section measurementss Ye ? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thics kYe target yields s Ye Decay data [II] Does your institute accept IAEA research fellows for training/experience? Yes 228 KOREA, REPUBLIF CO ROK-1 [1] Institute: Seoul National University Hospital Postal Address: Department of Nuclear Medicine Yungun-Dong,28 Chongro-Ku Seoul 110-744 Telephone: 82-2-7603805 Fax/E-mail: 82-2-7457690; [email protected] [2] Person in-charge: Jae Min Jeong (Title/Position) Director of Cyclotron Radiochemistryand Other senior staff: [3 ] Type of cyclotron: Negative Ion Manufacturer: EBCO Model: TR-13 installationf Yearo ) (i : : 1994 (ii) of any major reconstruction: [4] Particle beams available: 1 *^n* _-^ ' »J**/ . -"*IT? e $ v-£IH7 X)ual Beams 1 J '•iff!tf'l iUlflilll lllllsS3jw%t i * n ' ^ $*• 5 r . Beam energies/Range 13 (MeV) Typical currentt in s (uA) Employet ex d 25 (uA) Hours per week machine is in operation (excluding maintenance): 10 Hours per week employed in radionuclide production: 10 Hour weer spe k machine maintenance: 4 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others 229 ] [5 Radionuclides produced: Radionaclide Target Activity (GBq) Frequency Comments Produced Materia. , l - perfcatc. _ h (enrichment) "C 2 (not) "N 30 1 per month "N month1per n H2O 3 o "N2(97%) 3.7 week1per " 1S Fi H2 O 30 5 per week enriched H^O recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: \F-FDG 'O-Water N-Ammonia C-Acetate supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? If yes, whic oftenw h ho one ?d san medicas I ] l[9 research/diagnosis carrie site/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera 4 * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 1 engageu yo e nuclean di Ar r. a reactio[10] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections No Thick target yields No s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 230 KOREA, REPUBLIF CO ROK-2 ] [1 Institute: Korea Cancer Centre Hospital (KCCH) Postal Address: 215-4 Gongneung-Dong Nowon-Ku Seoul Telephone: 82-2-9742501 Fax/E-mail: 82-2-9753231 [2] Person in-charge: Lim SangDr. Moo (Title/Position) Head, Cyclotron Application Laboratory Other senior staff: Jong Doo Lee; Kwon Soo Chun; Seung Dae Yang Yong Sup Suh; Soon Hyuk Ahn; Jong Seo Chai Dong Hun Lee; Chang Woon Choi, Eun HeeKim [3] Typ cyclotronf eo : AVF Manufacturer: Scanditronix Model: MC50 Year: (i) of installation: 1987 (ii) of any major reconstruction: [4] Particle beams available: *H ;< *B ^He "He Dual Beams ^ '"*•, '' ; Beam energies/Range 50 25 50.5 (MeV) Typical currentt in s 200 (HA) Employet ex d 60 low current low current (uA) Hours per week machine is in operation (excluding maintenance): 40 Hours per week employed in radionuclide production: 20 Hours per week machine maintenance: 6 Additional application cyclotrone th f so : Neutron therapy, Neutron radiography, Thin layer activation Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 231 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq) per batch iSp S H2' O (97%} 20 weekper 3 production test "Cr naty base on demand °'Ga osZn 10 1 per week '"In na'Cd base demandon Uil '"TeO 15 week1per ""77 /W77 10 weekper 1 ] [6 Radionuclides planne producee b o dneat e th rn di future : Fproduction by Ne target High purity I production by Xe target on plan:, 11^C, 45~.Ti, 211At, ,. 186Re,D 124I T [7] Major radiopharmaceuticals produced: 67Ga-citrate Tl-Thallous201 Chloride Na'23I, I23I-mJBG, 18T-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san 20i 23 123 Ga-citrate,67 TICl, Na'I-mIBGI, 1 per week medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera 6 * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . r a [10reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 232 KOREA, REPUBLIC OF ROK-3 [I] Institute: Samsung Medical Centre Postal Address: Department of Nuclear Medicine 50 Ilwon-Dong, Kangnam-Ku Seoul 135-710 Telephone: 82-2-34102621 Fax/E-mail: 82-2-34102639; [email protected] [2] Person in-charge: Dr. Byung-Tae Kim (Title/Position) Chairman Other senior staff: Sang Zun Kim; Kyung Han Lee Yearn Sung Choe; Yong Choi [3] Typ cyclotronf eo : NegativeIon Manufacturer: GE Model: PETtrace Year: (i) of installation: 1994 majoy an f r(iio reconstruction) : [4] Particle beams available: IH *H lie "He Dual Beams "**& Beam energies/Range 16.5 8.4 yes (MeV) Typical currentt in s 75 60 (uA) Employet ex d 25 25 (UA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di 0 1 e production: Hours per week machine maintenance: 3 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 233 ] [5 Radionuclides produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C "N, 37 -weekper 2 n"N H2'°0 5.5 1 per -week o "N, 1.8 week2per e "p H2' O (97%) 45 6 per week enriched 18 H2 0 recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: F-FDG, F-Methylbenzylspiperone 1' C-Methionine N-Ammonia 15O-Water supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET 2 of 5 gamma camera * Gamma camera 5 * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections No Thico kN target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 234 NETHERLANDS NET-1 [1] Institute: Vrije Universiteit Postal Address: BV Cyclotron Vu De Boelelaan 1085c NL-1081 HV Amsterdam Telephone: 31-20-4449123 Fax/E-mail: 31-20-4449128 [2] Person in-charge: Dr.P.J. VanderJagt (Title/Position) General Manager Other senior staff: C. Hoekstra; F. Van Langevelde P.J. VanLenffen [3] Typ cyclotronf eo : Negative Ion Manufacturer: IBA s.a. Model: Cyclone 18/9 installationf Yearo ) (i : : 1997 majoy an (ii f r )o reconstruction : ] [4 Particle beams available: Beam energies/Range 18 (MeV) Typical currentt in s 80 35 (uA) Employet ex d (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 235 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) . per batch [61 Radionuclides planne producee b o dneat e th rn d i future : "F,!3N,*o "c, [7] Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? isF-FDG planned medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera 2 Singl* e Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10 r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 236 NETHERLANDS NET-2 [1] Institute: Vrije Universiteit Postal Address: CyclotronBV Vu DeBoelelaanl085c NL-1081 AmsterdamHV Telephone: 31-20-4449123 Fax/E-mail: 31-20-4449128 [2] Person in-charge: Dr.P.J. VanderJagt (Title/Position) General Manager Other senior staff: C. Hoekstra;F. Van Langevelde P.J. VanLenffen [3] Typ cyclotronf eo : Positive Ion Manufacturer: Philips Model: AVF installationf Yearo ) (i : : 1965 (ii) of any major reconstruction: [4] Particle beams available: . . v liar i. -,,„;!!» H *He Dual Beams ''^?lf fHT-Sfa : ~-• -*Be. J „*,k , ^ lifTi^St " * ?" * " '? Beam energies/Range 6-28 3-16 10-45 6-32 (MeV) Typical currents int 200 (uA) Employed ext 35 15 10 10 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance)5 6 : Hour weer spe k employe radionuclidn di 5 6 e production: Hours per week machine maintenance: 6 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 237 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C >°F 6/Ga °'Zn slmRb a'Kr(>99.8%) U,j 99%)'"Xe(> M'Tl 'u*Tl(>95.5%) [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: I8F-FDG 123I-MIBG, 123I-Iomazenil, 123I-Iodine hippuran, '23I-Sodium iodide 81 Rb-8ImKr generator [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 238 NETHERLANDS NET-3 [1] Institute: Eindhoven University of Technology (TUE) Postal Address: Postbus513 NL-5600 MB Eindhoven Telephone: 31-40-2474048 Fax/E-mail: 31-40-2438060; [email protected] tue.nl ] [2 Person m-charge: R. Queens (Title/Position) Other senior staff: ] [3 Typ cyclotronf eo : AVF Cyclotron Manufacturer: Philips Model: AVF installationf Yearo ) (i : : 1963 majoy an (iif ro ) reconstruction: [4] Particle beams available: 1itH $•' V *H *He "He Dual Beams , * *£4 £.*!• , , Beam energies/Range 3-27 (McV) Typical currents int 100 (HA) Employet ex d 60 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 80 Hour weer spe k employe radionuclidn di e production: 40 Hours per week machine maintenance: 8 Additional application cyclotrone th f so : Element analysis Nuclear physics techniques Radiotherapy/Activation Analysis/Radiobiology/Physics: Others- 239 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [6] Radionuclides planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: Cyclotron company usedthe by Cygene Amersham- b.v. [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes yesf I , whic oftenw h ho one ?d san Through Cygene Amersham- b.v. medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 240 NETHERLANDS NET-4 ] [1 Institute: Eindhoven University of Technology (TUE) Postal Address: Postbus513 NL-5600 EindhovenMB Telephone: 31-40-2474046 Fax/E-mail: [2] Person in-charge: Dr.J.A. VanderHeide (Title/Position) Other senior staff: BotmanM. J.I. H.HagedoornL. [3] Typ cyclotronf eo : 2nd Harmonic dees with harmonic6th dees flattop Manufacturer: Home made Model: ILEC Year: (i) of installation: 1989 (ii) of any major reconstruction: [4] Particle beams available: *H *& JHe «He Dual Beams Beam energies/Range 3 (MeV) Typical currents int (uA) Employed ext 20 (uA) Hours per week machine is in operation (excluding maintenance): 20 Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Microbeam PIXE analysis 241 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] engageu a. yo e nuclean dAr i e yor ureactio engagen cross-sectiod in nuclearn reactiomeasurementsn cro: ? No b. Which typ nucleanucleaf f >eo o e useu useu r datdatyo vo ? ? o o ad d Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 242 NETHERLANDS NET-5 [1] Institute: Groningen University Hospital Postal Address: PET Centre P.O.30.001Box NL-9700 GroningenRB Telephone: 31-50-3613311 Fax/E-mail: 31-50-3611687 [2] Person in-charge: Prof. VaalburgW. (Title/Position) Other senior staff: A. M. J. Paans; P. H. Elsinga [3] Type of cyclotron: AVF Manufacturer: Scanditronix Model: MC17F Year: (i) of installation: 1991 majoy an (iif r o )reconstruction : [4] Particle beams available: IjCf , ^ t . _ __JQ -. *H , ^He "He Dual Beams Beam energies/Range 17 8.5 (MeV) Typical currents int 50 50 (uA) Employed ext 30 50 (uA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 10 Hours per week machine maintenance: 3 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 243 [5] Radionuclides produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C N2+1%O2 21.06 21-22weekper 6 "N H2' O + 1 \iM 8.06 16-17 per -week circulating EtOH target "0 N-, + 1%O2 5.36 22-23 "F (80-96%)H^O 7.85 5-6weekper [6] Radionuclides planned to be produced in the near future: "C, 13N, 150, /rF [7] Major radiopharmaceuticals produced: I8F-FDG, '*F-Fluorocarazolol N-Ammonia nO-Water, 15O-Carbon Monoxide 11 C-Acetate, L-l-nC Tyrosine [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san ? / ? / NO2 / NO} for plant physiology 25 time per year [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Yes * Positron Emission Tomography (PET) Yes [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 244 NETHERLANDS NET-6 [1] Institute: Mallinckrodt Medical B. V. Postal Address: P.O. Box 3 NL-1755 ZG Petten Telephone: 31-224-567890 Fax/E-mail: 31-224-563566 [2] Person m-charge: J.F.J. van der Grift (Title/Position) Executive Director Operations Other senior staff: R.J. Reiff [3] Typ cyclotronf eo : Isochronoms Cyclotron Manufacturer: Philips Model: MC17F installationf Yearo ) (i : : 1966 majoy an f r o reconstruction ) (n : 1996 [4] Particle beams available: ijf sZrr * *» %fc 4L lie Hours per week machine is in operation (excluding maintenance): 100 Hours per week employed in radionuclide production: 100 Hours per week machine maintenance: 24 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology /Physics: Others. 245 ] [5 Radionuclides produced: Radionnclide Target Material Activity(GBq) Frequency Comments Produced (enrichment) per batch 0/Ga °'Zn not published 2 per week '"In lwCd not published 2 per week ""77 ""77 not published daily ] [6 Radionuclides planne producee b neao de t th rn d i future : ] [7 Major radiopharmaceuticals produced: 99Mo 99m- Tc generator Cyclotron products and derivates Labelling compounds [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? yesf I , whic oftenw h ho one ?d san Not published [9] Is medical research/diagnosis carried out on site/off site? Both siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 246 NETHERLANDS NET-7 [1] Institute: Mallinckrodt Medical B V. Postal Address: 3 P.O.Box NL-1755 ZG Petten Telephone: 31-224-567890 Fax/E-mail: 31-224-563566 [2] Person m-charge: J.F.J. van der Grift (Title/Position) Executive Director Operations Other senior staff: R.J. Reiff [3] Type of cyclotron: Negative Ion Manufacturer: IBA Model- Cyclone30 installationf Yearo ) (i : : 1993 majoy an f r o reconstruction ) (n : [4] Particle beams available: ; Ha*^-^~iMa-^ipitJP Irjr^r " "He * : *He Dual •£-:&» " f Beams Beam energies/Range 15-30 yes (MeV) Typical currentt m s (uA) Employet ex d 2x180 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 15 : Hours per week employed in radionuchde production: 150 8 1 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analy sis/Radiobiology/Physics: Others 247 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 0/Ga °8Zn not published week2per s'Rb S2Kr not published week4per '"In "vCd not published 2 per week U*j U4Xe not published week4per «"Tl MJJ not published daily [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: Tc m Mogenerator - Cyclotron products and derivates Labelling compounds [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? If yes, which ones and how often? Not published [9] Is medical research/diagnosis carried out on site/off site? Both If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 248 NORWAY NOR-1 [1] Institute: University of Oslo Postal Address: Department of Physics P.O. Box 1048, Blindern N-0316 Oslo Telephone: 47-22-856460 Fax/E-mail: 47-22-856422 [2] Person in-charge: Prof. Magne Guttorusen (Title/Position) Other senior staff: John Rekstad Svein Messelt [3] Typ cyclotronf eo : Sector focusing Manufacturer: Scanditronix Model: MC35 Year: (i) of installation: 1979 majoy an (ii f r )o reconstruction : [4] Particle beams available: ^f.^Sf-.'J-rr '•X.,: ;|«,fj»?M r ..'/•"jHe-, "He Dual Beams •I'-l-A^f <**£< * "' - >v- Beam energies/Range 35 17 47 35 (MeV) Typical currents int 100 80 10 20 (HA) Employed ext 70 50 5 10 (HA) Hours per week machine is in operation (excluding maintenance): 5 Hour weer spe k employe radionuclidn di e production: 2 Hours per week machine maintenance: 5 Additional applications of the cyclotron: Radiotherapy/Activation Analy sis/Radiobiology/Physics: Others: Nuclear Physics. The cyclotron is mainly devotes to nuclear structure studies using particle gamma coincidence 249 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "'At Bi MBq 400 1 per week [6] Radionuclides planned to be produced in the near future: 18 ] [7 Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? No siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurementso N ? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections No Thick target yields No Decay data No [11] Does your institute accept IAEA research fellows for training/experience? Yes 250 POLAND POL-1 [1] Institute: Henryk Niewodniczanski Institue of Physics Postal Address: Radzikowskiego152 PL-31-341 Krakow Telephone: 48-12-3722 02 Fax/E-mail: 48-12-37 [email protected]; 54 [2] Person in-charge: Dr. Barbara Petelenz (Title/Position) Head Laboratory ofthe of Physical Chemistry Other senior staff: Ewa Ochab; Edmund Bakewicz ] [3 Typ cyclotronf eo : Isochronous, K-factor60 = Manufacturer: This Institute Model: AIC-144 Year: (i) of installation: 1994 (ii) of any major reconstruction: 1997 ] [4 Particle beams available: ^H 'J fH^,__^ , - Hours per week machine is in operation (excluding maintenance): Planned 1998for Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional applications of the cyclotron: In Vitro radiobiological studies Development ofhadron therapy Pilot irradiations of solid targets Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Automated target assembly beingis designed 251 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced . (enrichment) batcr pe h [61 Radionuclides planne producee b o dneat e th rn d i future : Ce In, 67 f~,Ga,I, 123 T T ^ [7] Major radiopharmaceuticals produced: 67Ga-Citrate (planned) supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? Off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurementso N ? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 252 POLAND POL-2 ] [1 Institute: Warsaw University Postal Address: Heavy Laboratory,Ion PasteurauL 5A PL-02-097 Warszawa Telephone: 48-22-65821 20 Fax/E-mail: 48-22-659 2714 [2] Person m-charge: KowrackiProf. hab.Jan Dr. (Title/Position) Other senior staff: Tomasz Czosnyka Jerzy Jastrzebski [3] Type of cyclotron: A VF, 4-sector, 2-dee, 2 m diameter cyclotron Manufacturer: Magnet - Dubna, rest all Polish parts Model: installationf Yearo ) (i : : 1994 majoy an f r(ii o reconstruction) : ECR installation 1997 [4] Particle beams available: *H . M *He "He Dual Beams Beam energies/Range * (MeV) Typical currents int. (HA) Employed external ("A) o - Ar »r A r \ 0 ANe, 4 y ^ / Ne, n O, i f \ N, c MeV/n ~5 * C, after ECR installation Hour weer spe k machin operation i s ei n (excluding maintenance): 100 Hours per week employed in radionuclide production: Hours per week machine maintenance: 24 Additional application cyclotrone th f so : Basic research e.g.,Coulomb excitation, Giant Dipole Resonances In-beam high-spin spectroscopy Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Radioactive decays in He-jet system and isotope separation in-line 253 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [61 Radionuclides planne producee b o dneat e th rn di future : 123I, '"In [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? Planned after the ECR installation [9] Is medical research/diagnosis carried out on site/off site? siten o f , I indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thick target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 254 ROMANIA ROM-1 ] [1 Institute: National Institute for Research & Development for Nuclear Physics & Engineering - Horia Hulubei (INPE-HH) Postal Address: 1 Nuclear Reactor Street RO-76900 Bucharest-Magurele Telephone: 401 7807040/4413 Fax/E-mail: 4209101401 ;[email protected] [2] Person in-charge: Eng. Chem. Dana Voiculescu (Title/Position) Other senior staff: Eugen Ivanov, Dan Plostinaru, Petru Racolta, Bogdan Constrantinescu, Dumitru Catana, Florian Constanti, Liviu Popa-Simil, Mihai Dumitru, Dorin Dudu, Alexand Popa-Nemoiu [3] Typ cyclotronf eo : Classical, variable energy, 60 cm magnetic pole radius Manufacturer: URSS Petrograd- (Leningrad) Model: U-l 20/1956 Year: (i) of installation: 1957/1958 (ii) of any major reconstruction: 7970 development of 7 beam transport lines [4] Particle beams available: • "*TT« - .» : • " '3£^ tl^^afrrr * •> 'gsj^i^^Ktl. „*„_.t , ^ "He Dual **•*"** " ^^ •**"^'$3r£ w *H« : -*^* T "^^S *-2"^!;"« &$&$&. " Beams Beam energies/Range 0.7 - 14 1.4-14 2.1-42 2.8-28 (MeV) Typical currents int. 150 200 100 50 (uA)* Employed external 30 40 1 20 (uA) *We do not know exactly the internal beam because of multiple molecular species present at the final radius (example: If, H-H, H-H-H) Hours per week machine is in operation (excluding maintenance): now 24 < ~ 100 before 1989 Hours per week employed in radionuclide production: 0 Hour weer spe k machine maintenance: >20 Additional application cyclotrone th f so : Elemental analysis (PIXE, PIGE, RBS), Hyperfine interactions (PAC, TDPA, C/D), Fast neutron generation, Thin layer activation (TLA), Charged particle activation analysis (CPAA) Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: Design for positron generation in-line with cyclotron 255 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C ,OB 0.1 experiment1 7955 <«F H,'*0 few GBq week1per weeksfew "Na ^Mz 0.01 1 experiment study "Mn )lCr 0.01 experiments2 study "Fe "mn 1.50 week1per until 1985 0/Ga "Cu 0.1 1 experiment study luyCd >WA* 10MBg_ week1per until 1987 '"I '"Te/h'Sb 0.1 week1per study ] [6 Radionuclides planne producee b neao de t th r n di future : V 123I,T 67~(ja [7] Major radiopharmaceuticals produced: supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st r o institutionsN ? yesf I , whic oftenw h ho one ?d san past preliminaryNote:the the In experiemtns werer made with cooperation of the Colentina Hospital, Department of Nuclear Medicine. wereFe deliveredCdand INPEthe Centre 's to Radioisotopefor Preparatiion where sources were made and sold to non-ferrous mines applications.XRF for medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Off site siten Ifo , indicate imaging devices available number *511KeVSPET 7 Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 256 RUSSIAN FEDERATION RUS-1 [1] Institute: Bakoulev Scientific Centrefor Postal Address: Cardiovascular Surgery Roubevsekoe135 sh 121552 Moscow Telephone' 7-95-2373230 Fax/E-mail 7-95-2372172 [2] Person m-charge: Dr I. P Aslamdis (Title/Position) Head Radiodiagnostics ofthe Laboratory Other senior staff: M. N. Vakhromeyeva DezevyankoP. E. [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS-11 installationf Yearo ) (i : : 1998 (planned) (n) of any major reconstruction: [4] Particle beams available: •Ijtr *rtS 4 ^ P" ••>£ -'* '^^^B.s^^ft• C »••41 % He Dual Beams "•£ ~& 4- - Beam energies/Range 11 (MeV) Typical currents int. (HA) Employed external 50 (HA) Hours per week machine is in operation (excluding maintenance): 32 planned Installation underway Hour weer spe k employe radionuclidn di e production: 32 planned Hours per week machine maintenance: 4 planned Additional applications of the cyclotron Radiotherapy/Activation Analysis/Radiobiology/Physics: Others- PET 257 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch [6] Radionuclides planne producee b o dneae t th rn di future : "C. !3N,15 0 [7] Major radiopharmaceuticals produced: (planned) T-FDG N-Ammonia C-Acetate O- Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Planned If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomograph1 y (PET) engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurementso N ? . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 258 RUSSIAN FEDERATION RUS-2 [I] Institute: Cyclotron Co. Ltd. Postal Address: Bondarebko1 Sq. 249020 Obninsk Telephone: 7-95-2552385 Fax/E-mail: 9-95-2552326 [2] Person in-charge: Prof. N. N. Krasnov (Title/Position) Director General Other senior staff: A. A. Tonomarev Dr. Y. G. Sevastianov [3] Type of cyclotron: Classical Cyclotron Manufacturer: Scientific Institute, Electrophysics, PetersburgSt. Model: U-150-1 installationf Yearo ) (i : : 1963 (ii) of any maj or reconstruction: 1993 [4] Particle beams available: i i 4• ^ , T *J ;,;,a * - ^H. :, e "frjjri* , * o - *HfeT Dual Beams " „ «3>£ * t JVfrtffI f * < - t Beam energies/Range 22-28 22 44 (MeV) Typical currents int. 77350 - 700 400 (uA) Employed external 50 (UA) Hour weer spe k machin operation i s ei n (excluding maintenance): 168 Hour weer spe k employe radionuclidn di e production: 140 Hour weer spe k machine maintenance: 28 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: In 1998 it is planned to begin producing the radionuclides (second)withnew a cyclotron 259 [5] Radionuclides produced: Radionnclide Target Material Activity. , (GBq) „ Frequency Comments Produced (enrichment) per batch "Co JtfM ay ordered orderedas °'Ga osZn f'Zn) " " ™Ge Ga,Ni " •• "Sr Rb u " ysy Sr •• " lw WV a " Cd AK '"In luCd("'Cd) "yCe La 1ViAu Pt *"Tl wn n " [6] Radionuclides planne producee b o dneae t th rn di future : 67 Cu, mPd, I24 [7] Maior radiopharmaceuticals produced: 7 7 , In , 67-Ga lllj 201 T* supplu yo o y D radionuchdes/radiopharmaceutical[8] otheo st r institutions? Yes If yes, whic oftenw h ho one ?d san 139 m 20I 67 68 85 88 109 Co,i? Ga,Ge,Sr,Y,Cd, Ce, Au, Tl medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thick target yields Yes Decay data No [11] Does your institute accept IAEA research fellows for training/experience? Yes 260 RUSSIAN FEDERATION RUS-3 [1] Institute: Institute Human ofthe Brain Postal Address: Pavlov9 Street St. Petersburg 197376 Telephone: 7-812-2342359 Fax/E-mail: 7-812-234234 [email protected]; ru nw. [2] Person in-charge: Name not provided (Title/Position) Other senior staff: Eya Mrsonzhnikav [3 ] Typ cyclotronf eo : Fixed energy, PositiveIon Manufacturer: Scanditronix Model: MC-17 Year: (i) of installation: 1990 majoy an (ii f r)o reconstruction: ] [4 Particle beams available: *H '^ *, IB 'He "He Dnal Beams ' • ,«i;&*,, - Beam energies/Range 17 8.5 44 (MeV) Typical currents int. 18-40 40 400 (HA) Employed external (uA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 9 Hours per week machine maintenance: Additional applications of the cyclotron: Radiochemistry /PET Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 261 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C A^ (high purity) 18i week2per "N underO 2 H 2 H 14 2-3 per week '=0 N2 + 1% O2 7 3-5 per week ISp lts H2 O (96%) 7-11 week2per [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: lfC-Methionine, "C-Pyruvate, "C-Acetate, nC-L-DOPA, 'N- Ammonia O- Water 'F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No yesf I , whic oftenw h ho one ?d san medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Research on site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean dAr i r. a [10reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction croso sN sections Thick target yields Yes o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 262 RUSSIAN FEDERATION RUS-4 ] [1 Institute: KhlopinV.G. Radium Institute Postal Address: 2nd Murinsky AV 28 St. Petersburg 194021 Telephone: 7-812-2476181 Fax/E-mail: 7-812-2378095 [2] Person in-charge: Name providednot (Title/Position) Head of Nuclear Reaction and Nuclear Medicine Laboratory Other senior staff: [3] Typ cyclotronf eo : Manufacturer: Efremov NIIEFA Model: MGC20 Year: (i) of installation: 1988 (ii) of any major reconstruction: [4] Particle beams available: • •« H * H I , , „ *He ^e Dual Beams . - . „ < «,^S ^1SJ?V r ^ Beam energies/Range 2-18 2-10 8-24 Hours per week machine is in operation (excluding maintenance): 30 Hour weer spe k employe radionuclidn di e production: 30 Hours per week machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 263 [5] Radionuchdes produced: Radionuclide Target Materia: l Activity Frequency Comments Produced I (enrichment• : ) (GBq)per batch >* e F H2' O (96%) 50 4 per week enriched H2 O recovery juj '"Te02 10 2 per week [6] Radionuclides planne producee b do neat e th rn d i future : 67Ga, [7] Major radiopharmaceuticals produced: 1- 123 Sodium Iodide, 123I-Ortho-Iodohippurate supplu yo o y D [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? About 20 hospitals twice a week [9] Is medical research/diagnosis carried out on site/off site? Offsite If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 264 SAUDI ARABIA SAU-1 [1] Institute: King Faisal Specialist Hospital and Research Centre Postal Address: P.O. Box 3354 Riyadh 11211 Telephone: 966-1-4647272 ext. 31770 Fax/E-mail: 966-1-4424743; [email protected] [2] Person in-charge: Eng. Edward Daniel Carroll (Title/Position) Head of Cyclotron Operations Other senior staff: Salmon Mohamed Miliebari George Miller [3] Typ cyclotronf eo : Positive ion, A VF, electrostatic extraction Manufacturer: The Cyclotron Corporation Model: CS30 Year: (i) of installation: 1981 (ii) of any major reconstruction: [4] Particle beams available: - •**»»• ," : -• ^^Sjs_ -IHejf"^ l '$*• -. Dual Beams " * 5 *" • » -••*>, j-v-" •>.* "/•> Beam energies/Range 26.5 15 38 29.5 (MeV) Typical currents int. 100 (300) (135) (90) (HA) Employed external 50 (100) (60) (40) (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 40 Hours per week employed in radionuclide production: 38 Hours per week machine maintenance: 5 Additional applications of the cyclotron: Until 1991 werewe able accelerateto other particles. haveWe only protons morefor than years.six Proton currents typicalour are operation.. Others are machine specification. Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Two hours(2) target development 265 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment< ). per batch ISp H2"O, 95+% 25 4 per week "N H2'°O, Nat 7.4 weekper 3 °'Ga MZn, 99+% 25.4 1 per week recoveryZn y'Rb/e""Kr natKr 2.9 5 per week recoveryKr '"I "4Te, 96+% 13.6 week4per u*Te recovery t()l rpj ""77, 97+% 24.9' 1 per week MiTl recovery product, exceptB 77 EO t separationt a a * calculatedB .201 backBO o t [6] Radionuclides planne producee b do neae t th r n di future : 11C, '"In [7] Major radiopharmaceuticals produced: I2:'/- Sodium Iodide (oral and capsules), I23l-Ortho-Iodohippurate, 123I- mlBG I-Iodohippuran Ga-Gallium citrate, Tl-Thallous201 chloride, 18F-FDG 13N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 14 hospitals in Saudi Arabia varies from 4 times a week to 1 time per month 1 hospital Qatar in week per 1 1 center in West Asia 1 per month medicas I ] l[9 research/diagnosi siten O s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? Yes . b Which typ nucleaf eo useu r dat?yo o ad Reaction cross sYe sections Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 266 SOUTH AFRICA SAF-1 [I] Institute: National Accelerator Centre (NAC) Postal Address: P. O. Box 72 Faure 7131 Telephone: 27-21-8433820 Fax/E-mail: 27-21-2721843 [2] Person in-charge: Prof. J. F. Sharpey-Schafer (Title/Position) Director ofNAC Other senior staff: R. Pretorius [3] Type of cyclotron: Separated-sector cyclotron with a solid pole injector cyclotron Manufacturer: NAC Model: Year: (i) of installation: Operation started in December 1986 majoy an (ii f r)o reconstruction: Second injector cyclotron 1994n i [4] Particle beams available: /L"''~3|J^fJl|l |'>;|ailf : J, fl e- ;f;,*He . Dual Beams - 5 ? ~.,a - Beam energies/Range 25-200 50 - 700 50 - 1000 20 - 0 5 (MeV) Typical currents int. 85at66MeV / 1 7 ("A) Employed external 85at66MeV 1 1 7 G*A) Hour weer spe k machin operation i s ei n (excluding maintenance): averagethe 148 on Hours per week employed in radionuclide production: 33 Hours per week machine maintenance: averagethe 20on Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: All of them Others: 267 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch nat "Na MK 9-75 3 - 4 per year 0/Ga natZn 13 1 per week s'Rb/y"nKr na'Kr 1 2 per week '"In natrIn 0.5-1.0 2 per month '"I Nal 11 week1per liyCe na'Pr 10 first production run £01 rrn "a'Tl week1per * at BOB except 77, product at separation calculated back to EOB ] [6 Radionuclides planne producee b o neade t th rn di future : I8F, mPd [7] Major radiopharmaceuticals produced: 1231- Sodium Iodide (oral injection,and capsules), 123I- mlBG, Ga-Gallium citrate 81 Rb/81mKr generator supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st s r institutionsYe ? If yes, which ones and how often? nuclear30 medicine centers Southin Africa, weeklyon basis 1 nuclear medicine department Nambiain DuPont Merck Co Na(22 at 3 - 4 times per year) Amersham International ( Na at 1 -2 times per year) medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 268 SPAIN SPA-1 [1] Institute: Centra PET Complutense Postal Address: C/Manuel Bartolome Cossio 28040 Madrid Telephone: 34-1-53448 96 Fax/E-mail: 34-1-55308 45 ] [2 Person m-charge: JoseDr. Luis Garreras (Title/Position) Other senior staff: [3] Type of cyclotron: Superconducting, negativeion Manufacturer: Oxford Electronics Model: OSCAR Year: (i) of installation: 1995 (n) of any major reconstruction: [4] Particle beams available: •&. inf-s^ss ,.s • j£l ^z. -. & 5He iHe Dual Beams i'*-^:! Jb& *L Beam energies/Range 12 (MeV) Typical currents int. (HA) Employed external 50 (HA) Hours per week machine is in operation (excluding maintenance): 10 Hours per week employed in radionuclide production: 10 Hour weer spe k machine maintenance: 2 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 269 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "N H2'°0 3.7 week2per ISp S H2' O (98%) -50 5 per week [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: N- ammonia !F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? We plan to supply 18F-FDG to other institutions medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? Yes, on site & off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean di Ar r. [10a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 270 SPAIN SPA-2 [1] Institute: Clinica Universitaria de Navarra Postal Address: Apartadp, 4029 31080 Pamplona Telephone: 34-48-172294 Fax/E-mail: 34-48-172294; [email protected] [2] Person in-charge: RichterJ.A. J. M. Marti-Climent (Title/Position) Chief of Nuclear Medicine Physicist Other senior staff: I. Penuelas C. Sanchez [3] Typ cyclotronf eo : Negative Ion, fixed energy Manufacturer: Ion Beam Applications, s.a. Model: Cyclone 18/9 Year: (i) of installation: 1996 (li) of any major reconstruction: [4] Particle beams available: *m ., ... 3H *He 1tte Baal Beams * Beam energies/Range 18 9 yes (MeV) Typical currents int. 15 10 foA) Employed external 15 10 (»iA) Hours per week machine is m operation (excluding maintenance): 3.5 Hours per week employed in radionuclide production: 3.5 Hours per week machine maintenance: 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 271 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch llf "C N 99.999%2 8 3 per week < 0.5%2 O "N H7'°0 1.5 month1per ! "0 *N2 99.99% 8 2 per week <1%O2 tap 1S H2 0 30 5 per week enriched H2'*O recovery [6] Radionuclides planned to be produced in the near future: 18F-F2 ] [7 Major radiopharmaceuticals produced: C-Methionine N-Ammonia O- Water T-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h oneho ?d san ISF-FDG, daily Beginning in September, 1997 [9] Is medical research/diagnosis carried out on site/off site? Both, siteon Diagnosis off site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 272 SWEDEN SWE-1 [1] Institute: Uppsala University Postal Address: PET Centre, UAS S-75185 Uppsala Telephone: 46-18-183381 Fax/E-mail: 46-18-183390; [email protected] ] [2 Person in-charge: Prof. Bengt Langstrom (Title/Position) Other senior staff: Gunnar Antoni; Yvonne Andersson; Mats Bergstrom; KarlJohan Fajth; Goran Westerberg [3] Type of cyclotron: Fixed energy isocronous cyclotron Manufacturer: Scanditronix Model: MC17 Year: (i) of installation: 1991 (ii) of any major reconstruction: ] [4 Particle beams available: • „ ' %T ' '~ ^£$$B&" .- •$. _JJHS<-A ^ ;») Dual Beams ?j?* **j I'li* *si** Beam energies/Range 77 8.5 (MeV) Typical currents int. GiA) Employed external 45 40 GiA) Hours per week machine is in operation (excluding maintenance): -50 Hour weer spe k employe radionuclidn di e production: -30 Hour weer spe k machine maintenance: - 2 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 273 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N, up to 50 ~25weekper n o "N2 lineon ~4 per week >«F a H2' O (80 - 98%) -50 ~3 per week '°Br Cu"Se2 ~1 weekper 2 1- [6] Radionuclides planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: *150 different tracers 1 1 I I II C-Methionine, C-Hydroxytryptophane, C-Raclopride, "C-Acetate, "C-DOPA 15O-Water, 'sO-Carbon Monooxide, I5O-Oxygen, 18F-FDG supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st rs institutionsYe ? If yes, which ones and how often? Beginning September,in 1997 !8F, 76Br [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511 KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomograph2 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction croso sN sections Thick target yields No s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 274 SWITZERLAND SWI-1 [1] Institute: University Hospital Geneva Postal Address: 24, rue Micheli-du-Crest CH-1211 Geneva Telephone: 41-22-3727165 Fax/E-mail: 41-22-3727169 [2] Person in-charge: BeyerProf.J. G. (Title/Position) Other senior staff: Ch. Morel [3] Typ cyclotronf eo : Negative Ion, fixed energy Manufacturer: Ion Beam Applications, s.a. Model: Cyclone 18/9 installationf Yearo ) (i : : 1997 (ii) of any major reconstruction: [4] Particle beams available: •£i'* **^3DT * , , • "Saf ' e , tov - Dual Beams Alltel?w!*^ ^ stti ./-, » ^*- 2 * > £ • « v' fty>r~f-rei' v^.-^r* , «.. IB, '*%(,>* Beam energies/Range 75 9 yes (MeV) Typical currents int. (»iA) Employed external (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 40 planned Installation underway Hours per week employed in radionuclide production: 30 planned Hour weer spe k machine maintenance: 5 planned Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 275 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch [61 Radionuclides planned to be produced in the near future: I3N,C, 64Cu, 67Cu, 86Y, 123I, 124I ] [7 Major radiopharmaceuticals produced: 18F-FDG and others planned supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, whic oftenw h ho one ?d san 18FDG to 8 Centres daily beginning in September, 1997 [9] Is medical research/diagnosis earned out on site/off site? Yes siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera 2 * Single Photon Tomography (SPET) 2 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i r. a [10reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics Ye k target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 276 SWITZERLAND SWI-2 [I] Institute: Paul Scherrer Institute (PSI) Postal Address: CH-5232 Villigen-PSI Telephone: Not provided Fax/E-mail: Not provided [2] Person in-charge: Prof. P. A. Schubiger (Title/Position) Other senior staff: R. Schwarzbach J. Jegge [3] Typ cyclotronf eo : AVF Cyclotron Manufacturer: Phillips Model: installationf Yearo ) (i : : 1974 (ii) of any major reconstruction: [4] Particle beams available: ^^rfJirSt Dual Beams " ••> r "?^;ic^^™*^*' V-Y'lHfc./-"- iHe . • •'- ~{ i Beam energies/Range (MeV) 10-70 10-60 30-150 20-120 Typical currents int. (uA) Employed external 70 10 10 10 (uA) Hours per week machine is in operation (excluding maintenance): Hours per week employed in radionuclide production: 150 hours operationin Hours per week machine maintenance: 18 hours service and set up Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 277 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C N2 37 week2per "0 02 1 12 per week >* e F H2' O (96%) 37 3 per week "Fe Ni 1 month1per <"Cu Zn 1.5 1 per week /0Br KBr 5 2 per month USj Kl 20 2 per month [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 15O-Water "C-Flumazenil, "C-Radopride, '!C-Methionine, "C-Ketamine I8F-FDG, I8F-DOPA, supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? 18F-FDG back-up production hospitals5 to [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomographs Ye y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 278 SWITZERLAND SWI-3 [1] Institute: University Hospital Zurich Postal Address: Raemistrasse. 100 CH-8081 Zurich Telephone: 41-1-2551111 Fax/E-mail: 41-1-2554428; [email protected] [2] Person in-charge: Name not provided (Title/Position) PhD, Radiochemist Other senior staff: [3] Typ cyclotronf eo : Fixed energy, negativeion Manufacturer: General Electric Model: PETTrace Year: (i) of installation: 1994 majoy an (ii f r)o reconstruction: [4] Particle beams available: ,-£•* sdfcw f : ~ ' ~ x ~ > ^He-• 5" Dual 'Beams :S*.:;| L.. ^He-s;^! , > * *S* ~* ; . ,* \ "* *&* * *y WUT*J3s/3£ £gj«£4&,K> Beam energies/Range 16.5 5.5 (MeV) Typical currents int. (HA) Employed external (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 40 Stand-by Hours per week employed in radionuclide production: 20 Beam on target Hour weer spe k machine maintenance: 3 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 279 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C 6 4 per week Nf "N H>hO 5 week10per "0 N2(+02) MBq/min150 weekper 2 for 2-70 hours each <* a F H2' O (97%) 80 week7per enriched water recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuricals produced: N- Ammonia, O- Water C-Flumazenil F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 2 hospitals 1 time per week 3 hospitals 2 times per week [9] Is medical research/diagnosi siten O s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomographs Ye y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 280 SYRIAN ARAB REPUBLIC SYR-1 [1] Institute: Atomic Energy Commission of Syria (AECS) Postal Address: P.O. Box 6091 Damascus Telephone: 963-11-6112289 Fax/E-mail: 963-11-6111926/7 [2] Person in-charge: Dr. Abdul Hamid Al-Reyyes (Title/Position) Other senior staff: [3 ] Type of cyclotron: Negative Ion, variable energy Manufacturer: Ion Beam Applications, s.a. Model: Cyclone 30 installationf Yearo ) (i : : 1998/9 (ii) of any major reconstruction: [4] Particle beams available: ~< -••" %«r ,1 ,4-jHe : Dual Beams Beam energies/Range 75-50 yes (MeV) Typical currents int. (HA) Employed external 350 (uA) Hours per week machine is in operation (excluding maintenance): Installation to begin in 1998 Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional applications of the cyclotron: Radiotherapy/ Activation Analysis/Radiobiology/Physics: Physics Others: 281 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [6] Radionuclides planne producee b o neade t th r n di future : "C, "F. 6?Ga, !23I, 124I, 2*Tl [7] Major radiopharmaceuticals produced: 18F-FDG 67 Ga-citrate 20lTl-chloride Others planned supplu yo o yD radionuclides/radiopharmaceutical ] [8 o st other institutions? Yes, If yes, whic oftenw h ho one ?d san planned medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Research & diagnosis on site If on site, indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) Will availablebe * Positron Emission Tomography (PET) Will be available [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 282 UNITED KINGDOM UK-1 [1] Institute: University of Aberdeen Postal Address: Department ofBiomedical Physics & Bioengineering Foresterhill, Aberdeen, AB25 2ZD Telephone: 44-1224-681818 51155ext Fax/E-mail: 44-1224-685645 [2] Person in-charge: WelchA. Dr. (Title/Position) Director, Aberdeen CentrePET Other senior staff: P. Mikecz; M. Dodd [3] Typ cyclotronf eo : Positive Ion, Fixed Energy Manufacturer: The Cyclotron Corporation Model: CS-30 installationf Yearo ) (i : : 1987 (ii) of any major reconstruction: [4] Particle beams available: :•!$&.,£*£$. "SM/fH ,* 'He 3?e Dual Beams Beam energies/Range 26 75 (MeV) Typical currents int. 100 200 (HA) Employed external JO-20 20 (uA) Hours per week machine is in operation (excluding maintenance): 10 Hours per week employed in radionuclide production: 10 Hour weer spe k machine maintenance: 10 Additional application cyclotrone th f so : Radio therapy/Activation Analysis/Radiobiology/Physics: Others: This cyclotron will stop operationits ofaround 1997.end the It111 will replacedbe RDS a by 283 ] [5 Radionuclides produced: Radionuclide Target Material Activity(GBq) Frequency Comments Produced (enrichment) per batch U "N CH4 1 2 per week "0 "N2 +1%02 1 per week continuous flow ISp v ' Ne + 0.3%F2 3-5 week3per ] [6 Radionuclides planne producee b neao de t th rn di future : [7] Major radiopharmaceuticals produced: 'F-FDG 'N-Ammonia, 'O- Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? Yes, on site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean di Ar [10 r. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 284 UNITED KINGDOM UK-2 [1] Institute: University of Aberdeen Postal Address: Department of Biomedical Physics Bioengineering& Foresterhill, Aberdeen,2ZD AB9 Telephone: 44-1224-681818 ext 51155 Fax/E-mail: 44-1224-685645 [2] Person in-charge: WelchA. Dr. (Title/Position) Director, Aberdeen PET Centre Other senior staff: P. Mikecz; M. Dodd ] [3 Typ cyclotronf eo : Negative Ion, Fixed Energy Manufacturer: CTI Model: RDS111 Year: (i) of installation: 1997 majoy an (ii f r)o reconstruction: [4] Particle beams available: 'H .** *He *He Dual Beams ^ ^ - V | ":- Beam energies/Range 11 (MeV) Typical currents int. 50 (uA) Employed external 35* (HA) Hours per week machine is in operation (excluding maintenance): -20 Hours per week employed in radionuclide production: -20* * Hours per week machine maintenance: «« 5 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: * Planned commence ofto end 1997 the at * Projected values 285 [5] Radionuclides produced: Radioonclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N, 40* U "N CH4 3* n I4 o N2 + 1% 02 3* >* IS F H2 0 5* weekper 4 * Estimated plannedfor operation commenceofto 1997end the at ] [6 Radionuclides planne producee b neao de t th rn d i future : [7] Major radiopharmaceuticals produced: 18F-FDG 13'N-Ammonia 15O-Water 11C-Amino acids [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Yes, on site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomograph1 y (PET) engageu yo e nuclean di Ar r. [10a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 286 UNITED KINGDOM UK-3 [1] Institute: The University of Birmingham Postal Address: School of Physics and Astronomy Edgbaston Birmingham2TT B15 Telephone: 44-121-4144704 Fax/E-mail: 44-121-4144704; [email protected] [2] Person in-charge: Prof. T.D. Beynon (Title/Position) Other senior staff: R.G. Green [3 ] Type of cyclotron: 60" Classical Manufacturer: University of Birmingham Model: Nuffield60" Cyclotron installationf Yearo ) (i : : 1948 (ii) of any major reconstruction: [4] Particle beams available: 1]H *H 'He *He Dual Beams Beam energies/Range 10 20 30 40 (MeV) Typical currents int. 1000 200 100 (HA) Employed external 50 20 30 (HA) *The Nuffield60" Cyclotron oldestthe is running cyclotron Hour weer spe k machin operation i s ei n (excluding maintenance): 110 Hours per week employed in radionuclide production: 110 Hours per week machine maintenance: Variable Additional application cyclotrone th f so : Used only for radioisotope production Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 287 [5] Radionuchdes produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "Na Mg 11 year2per °>Zn Cu 11 2 per year *'Rb NaBr 0.9 46 generators slRb a- ""Kr per week Generator wyCd AK 45 month1per [6] Radionuclides planned to be produced in the near future: As dictated by the market demand [1] Major radiopharmaceuticals produced: 8Im- KrRb 81 Generator supplu [8]yo o y D radionuclides/radiopharmaceutical otheo st r institutions? yesf I , whic oftenw h ho one ?d san Amersham International, monthly 46 Hositals throughout the United Kingdom for medical imaging during 50 weeks yearper medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) Industrial PET [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 288 UNITED KINGDOM UK-4 [1] Institute: The University of Birmingham Postal Address: School of Physics and Astronomy Edgbaston Birmingham B15 2TT Telephone: 44-121-4144704 Fax/E-mail: 44-121-4144704; [email protected] [2] Person in-charge: Prof. T.D. Beynon (Title/Position) Other senior staff: R.G. Green ] [3 Typ cyclotronf eo : Sector3 variable frequency, Pole36" Diameter Manufacturer: University of Birmingham Model: Radial Ridge Cyclotron installationf Yearo ) (i : : 7957 majory an f (iio )reconstruction : ] [4 Particle beams available: J 4 *H *H He He Dual Beams Beam energies/Range 72.5 33 24.5 (MeV) Typical currents int. 800 150 (HA) Employed external 200 50 50 (»iA) Hours per week machine is in operation (excluding maintenance): Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional applications of the cyclotron: Used only for F production Radiotherapy/Activation Analysis/Radiobiology/Phy sics: Others: 289 [5] Radionuclides produced: Radionoclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h >«F H2O 7.5 everyday [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Planned If yes, whic oftenw h ho one ?d san Plan to produce 18F-FDG to supply local hospitals [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 industrial PET [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 290 UNITED KINGDOM UK-5 [1] Institute: Wolfson Brain Imaging Centre Postal Address: Cambridge University Clinical School Box 65 Addenbrooks 's Hospital Cambridge CB22QQ Telephone: 44-1223-331823 Fax/E-mail: jcc24@wbic. cam.ac.uk [2] Person in-charge: Dr. John Clark Prof. John PickardD. (Title/Position) PET Science Director Clinical Director Other senior staff: [3] Typ cyclotronf eo : Negative Ion, Fixed Energy Manufacturer: General Electric Model: PETTrace Year: (i) of installation: 1995 majoy an (iif ro )reconstruction : [4] Particle beams available: IE *m *He "He Dual Beams Beam energies/Range 16.5 8.5 (MeV) Typical currents int. ftiA) Employed external 40 (tiA) Hours per week machine is in operation (excluding maintenance): available hours24 per day depends upon clinical demands Hours per week employed in radionuclide production: Hours per week machine maintenance: ~ 2 Additional applications of the cyclotron: The Wolfson Brain Imaging Centre dedicatedis studythe of to damaged brain neuro-intensive sitedMRI.is the It and usingin PET care environment to provide mininal transfer time for sick patients. Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 291 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C02 "ty up to 110 as required for "CHJ radiosynthesis "0 '•N, as required on-line <* 3 F H2' O(97%/20%) as required yes [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: 18F-FDG O- Water, O-Oxygen, O-Carbon Monoxide a C-radioligands supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511 KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thics Ye k target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 292 UNITED KINGDOM UK-6 [1] Institute: MRC Cyclotron Unit Postal Address: Hammersmith Hospital Ducane Road London W12 ONN Telephone: 44-181-3833775 Fax/E-mail: [2] Person in-charge: Prof. T. Jones (Title/Position) Other senior staff: V. W. Pike; Bruce McKay [3] Typ cyclotronf eo : Positive Ion, Variable Energy Manufacturer: Scanditronix Model: MC 40 MARK II installationf Yearo ) (i : : 1986 majoy an (ii f r )o reconstruction : [4] Particle beams available: • : ' H * * ~ '*Pl*• • ' J JHe *He Dual Beams Beam energies/Range 40 18 53 40 (MeV) Typical currents int. 65 65 30 30 (HA) Employed external 40 (HA) Hour r weespe k machin operation i s ei n (excluding maintenance)0 10 : Hours per week employed in radionuclide production: 100 Hours per week machine maintenance: 6 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Radiotherapy Others: 293 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced ^enrichment) batcr pe h ] "C *N2orN2/H2 regular M "0 N2 daily •*F S H2' 0 regular "Br e'Rb "Kr daily a- ""Kr "Kb Generator //Or '"I [6] Radionuclides planned to be produced in the near future: 94mTc, 64Cu ] [7 Major radiopharmaceuticals produced: Wide rangeF-labelledand ofC !I compounds 15O- Water I8F-FDG, 18F-DOPA, I8FU 11 C-Raclopride, !'C-Deprenyl, S-UC-CGP12177, R-nC-PK11195 "C-Diprenorphine, "C-WAY-100635, "C-RT1-55, "C-Flumazenil, "C-SCH23390, "C-MHED, "C-Thymidine [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Krypton-Sim generators daily 18F-FDG on request I8F-DOPA, request on 18FU miscellaneous isotopes on request [9] Is medical research/diagnosis carried out on site/off site? Yes siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) 4 clinical PET, and 1 animal PET engageu yo e nuclean dAr i . r a reactio[10] n cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experence? Yes 294 UNITED KINGDOM UK-7 [1] Institute: CyclotronMRC Unit Postal Address: Hammersmith Hospital Ducane Road LondonONN W12 Telephone: 44-181-3833775 Fax/E-mail: [2] Person m-charge: Prof T. Jones (Title/Position) Other senior staff: V.Pike,W Bruce McKay [3] Type of cyclotron: Oxygen-15 Generator Manufacturer: Ion Beam Applications,a s Model: 3D Year- (i) of installation: 1991 (n) of any major reconstruction: [4] Particle beams available: 1H P • "Hf » *He Dual Beams " sfi3 j* ^ " '*«•*1 "* ' 3T" ^ Beam energies/Range 3.2 (MeV) Typical currents int. (HA) Employed external (HA) Hours per week machine is in operation (excluding maintenance): 100 Hour weer spe k employe radionuchdn di e production. 100 Hours per week machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 295 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "0 "N2 [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: isO-Water supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 4 Clinical PET, 1 Animal PET engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurements? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 296 UNITED KINGDOM UK-8 [1] Institute: ThomasSt. Hospital Postal Address: The Clinical PET Centre London7EH SE1 Telephone: 44-171-9228068 Fax/E-mail: 44-171-6200790 [2] Person in-charge: MaiseyProf.N. G. (Title/Position) Chairman, Division of Radiological Sciences Other senior staff: Julie Sutcliffe; Paul Halstead Paul Marsden [3] Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 majoy an (li f r o )reconstruction : [4] Particle beams available: >'~ " *W iHe "He Dual Beams * H - ~7- , , *> 3>i r Beam energies/Range // (MeV) Typical currents int. 80 (HA) Employed external 30 (jiA) Hour weer spe k machin operation i s ei n (excluding maintenance)2 1 : Hours per week employed in radionuclide production: 12 Hours per week machine maintenance: 3 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: We maintain cyclotronthe ourselves have contractand no with CTI. We have 2 CPU's for I8FDG production 297 [5] Radionuclides produced: Radionuclide Target Activity (GBq) Frequency Comments Produced Material pertoatch (enrichment) 14\T "C N2 20 10 per week mainly experiments "N H2'°0+ 1.5 2 per week n SOvMEtOH o "N2:02 20 2 per week expensive method e >*F H2' O (96%) 50 weekper 5 high pressure silver target [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG, '*F-Fluoromisonidazole C-Methionine, C- Flumazenil 13N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 5 hospitals each 1 per week medicas I ] l[9 research/diagnosis carrie site/ofn o t dou f site? Research/ diagnosis on site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections No Thick target yields No Decay data No [11] Does your institute accept IAEA research fellows for training/expenence? No 298 UNITED KINGDOM UK-9 [1] Institute: Douglas Cyclotron Unit Postal Address: Clatterbridge for Oncology Bebington, Wirral L63 4JY Telephone: 44-151-3346366 Fax/E-mail: 44-151-3342845; andrzejk@cco. trust, co. uk [2] Person in-charge: AndrzejDr. Kacperek (Title/Position) Head of Cyclotron Unit Other senior staff: B. Marsland [3] Typ cyclotronf eo : A VF, Single Particle, Fixed Energy Manufacturer: Scanditroix Model: MC-62 installationf Yearo ) (i : : majoy an (iif ro )reconstruction : Beamline of proton therapy, 1988 [4] Particle beams available: "(,;:""• ,"*nr *H ,- * s X ' ™ *Efe "He Dual Beams >S w s * v " |tff?;"" * Beam energies/Range 62 nominal (MeV) Typical currents int. up to 50 (HA) Employed external 10 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): av. 6 Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Proton radiotherapy of ocular tumors Radiobiology (proton therapy support) Radiotherapy/ Activation Analysis/Radiobiology/Physics: Physics Research (e.g. Dosimetry) Others: 299 [5] Radionuclides produced: Radhmnclide Target Material Activity (GBq) < Frequency Comments Produced (enrichment) ;i ^HsritoateaiK MCu very small research quantities s'Rb/S!mKr na'Kr 300 mCi 1 per month development lu'Pd very small research quantities "'Ce very small research quantities [6] Radionuclides planned to be produced in the near future: I8F-FDG using !8O-water target, Colongas lived positron emitter brainfor research ] [7 Major radiopharmaceuticals produced: We do not the facilities on site [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 22Na, 57Ni, MCu, IOIPb, >39Ce infrequently to 2 Universities [9] Is medical research/diagnosis carried out on site/off site? Both.Yes siten Ifo , indicate imaging devices available number *511KeVSPET upgrade cameramay y the CCO with double-headed capability Gamm* a camera 1 * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 300 UNITED STATES OF AMERICA USA-1 [1] Institute: Good Samaritan Hospital Postal Address: Net PET Pharmaceutical Services 1111 E.McDowellRd. Phoenix AZ 85006 Telephone: 1-602-2394100 Fax/E-mail: 1-602-2392810 [2] Person in-charge: Tricia Giurlani (Title/Position) PDC Manager Other senior staff: David Stith; StiversJay [3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1990 (ii) of any major reconstruction [4] Particle beams available: AH -fa " • *He 4He Dual Beams .* «- T* J V **<"'-,'' * * Beam energies/Range 77 (MeV) Typical currents int. 40 - 100 (HA) Employed external 20-40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 3 - 5 7 : Hour weer spe k employe radionuclidn di e production: 5-70 Hours per week machine maintenance: 5-70 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 301 [5] Radionuchdes produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C "N, 74 1 per 2 months U nN H2">0 3.7 1-2 per month o "N.-^O,1 39: 7.4 1 patientper ~ 10 runs month <* 8 F H2' O (~ 97%) 15 week5per ] [6 Radionuclides planne producee b neao de t th r n di future : [7] Major radiopharmaceuticals produced: if,F-FDG 13[N - Ammonia, 11C- Methionine liO-Water supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? raF-FDG daily 13N-Ammonia ~ 1 per month medicas I ] l[9 research/diagnosi siten O s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 302 UNITED STATES OF AMERICA USA-2 [1] Institute: Lawrence Berkeley National Laboratory Postal Address: Centre for Functional Imaging Cyclotron1 Road, 55-121MS Berkeley, 94720CA Telephone: 1-510-4864083 Fax/E-mail: 1-510-4864 768; [email protected] [2] Person in-charge: Henry BrocklinDr. Van (Title/Position) Head, Radiopharmaceutical Chemistry Other senior staff: James O 'Neil Thomas BudingerF. [3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS111 installationf Yearo ) (i : : 1995 (ii) of any major reconstruction ] [4 Particle beams available: *H '<;*R ^He "He Dual Beams * *» *•>& tfefe:" i:« Beam energies/Range (MeV) // Typical currents int. (HA) Employed external 10-50 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 5-6 Hour weer spe k employe radionuclidn di e production: 5-6 Hours per week machine maintenance: av. 2 Additional application cyclotrone th f so : Isotope production for use in nuclear science applications, i.e., source injectionfor into LBNL inch- the 88 cyclotron Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 303 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 'Be 'Li /"Li 7 - 2 per year solid target "N H2'"0 + 2 per month SmMEtOH l«p I0 IS 98%)02(> 2 per week 02 ISp a "2 O (> 97%) 3 per week enriched I8 H2 0 recovery [6] Radionuclides planne producee b do neat e th rdn i future : 11C, 150 [7] Major radiopharmaceuticals produced: F-FDG, I8F-Fluoro-meta-tyrosine N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) 1 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i . r a [10reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 304 UNITED STATES OF AMERICA USA-3 [1] Institute: Crocker Nuclear Laboratory Postal Address: University of California, Davis 1 Bainer Drive, Davis, CA 95616 Telephone: 1-916-7521460 Fax/E-mail: 1-916-7520952 [2] Person in-charge: Manuel C. Lagunas-Solar (Title/Position) Senior Radiochemist Other senior staff: Nolan X. Zeng; Carlos M. Castaneda Krystyna Trzepla-Nabaglo; Omar F. Carvacho [3] Typ cyclotronf eo : 76 inch Isochronous Cyclotron Manufacturer: BrobeckW.M. Associates& Model: Year: (i) of installation: 1964-1966 (ii) of any major reconstruction: [4] Particle beams available: *H *& 'He *He Dual Beams Beam energies/Range 4-68 15-45 20-90 16-90 (MeV) Typical currents int (HA) Employed ext 30 40 1 40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 112 Hours per week employed in radionuclide production: 40 hours in 1980-1986; 4-8 hours per week in 1987-1993 Hours per week machine maintenance: -16 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: of All them Others: Food irradiation and conservation 305 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch l *p* ""'Afe 3.0-4.5 2-4weekper i^j* 3.7-7.4 4 per week ™Bi,™Bi na'Pb 180-370MBq year2-4per 123I production performed in 1980-1986 18F production in 1987-1993 [61 Radionuclides planne producee b o dneat e th rn di future : J8p> 205^ 206^67^ [7] Major radiopharmaceuticals produced: 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Benedict Nuclear week Pharmaceuticals,per 4 USA CO, University of California, Irvine, CA, USA 1-2 per week University of California, Berkeley, CA, USA 1-2 per week VA Hospital, Palo Alto CA, USA 1-2 per week National Institute of Health, MD, USA 2-4 per year year2-4 NeoRx Corporation, USA WA, medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Ojfsite If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 306 UNITED STATES OF AMERICA USA-4 [1] Institute: University of California-Irvine Postal Address: Brain Imaging Centre Irvine, 92697CA Telephone: 1-714-8242018 Fax/E-mail: 1-714-8242230; [email protected] [2] Person in-charge: . AhmodA.Dr Najafi (Title/Position) Other senior staff: [3 ] Typ cyclotronf eo : PositiveIon Manufacturer: Scanditronix Model: MC17 Year: (i) of installation: 1988 majoy an (ii f r)o reconstruction: [4] Particle beams available: . - l lf ; IH *He "He Dual Beams -<*.!*" * 1-,** Beam energies/Range 8-10 (MeV) Typical currents int 20 (HA) Employed ext 20 (UA) Hours per week machine is in operation (excluding maintenance): 12 Hours per week employed in radionuclide production: 12 Hours per week machine maintenance: 2-3 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 307 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b o neade t th rn d i future : [7] Major radiopharmaceuticals produced: I8 '*F-DOPA supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) Yes [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 308 UNITED STATES OF AMERICA USA-5 [1] Institute: University of California at Los Angeles Postal Address: Biomedical Cyclotron 10833 Le Conte Avenue Angeles,Los 90095CA Telephone: 1-310-8256231 Fax/E-mail: 1-310-8254517 [2] Person in-charge: N. Satyamurthy (Title/Position) Other senior staff: CookJoe Bernard Amarasekera [3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1990 (ii) of any major reconstruction [4] Particle beams available: *H ! • - SET *He ^He Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int. (HA) Employed external 40 (HA) Hours per week machine is in operation (excluding maintenance): 40 Hour weer spe k employe radionuclidn di 5 2 e production: Hours per week machine maintenance: 2-3 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 309 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch I4 "C N2 55 4 per week "N H2'°0 3 25 per week "0 'V, 74 16 per week <«F HfO (97%) 20 10 per week ,*F '*O2 (97%) 40 4 per week enriched O2 recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: F-FDG, F-Fluorodopa, F-Fluoro-m-tyrosine, 181'eF-Fluoroacyclovir, I8F-Fluoro-ethylspiperone, I8F- WIN "C-WIN, nC-Acetate, "C-Carbon Monoxide, 'N- Ammonia O-Water, 15O-Carbon Monoxide, >5O-Oxygen [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 6 [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections No Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 310 UNITED STATE AMERICF SO A USA-6 [1] Institute: University of California at Los Angeles Postal Address: Biomedical Cyclotron 10833 Le Conte Avenue Angeles,Los 90095CA Telephone: 1-310-8256231 Fax/E-mail: 1-310-8254517 [2] Person in-charge: N. Satyamurthy (Title/Position) Other senior staff: CookJoe Bernard Amarasekera [3 ] Typ cyclotrof eo n: NegativeIon Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1990 majoy an (ii f r) o reconstruction [4] Particle beams available: 'H *n "He *He Dual Beams Beam 11 yes energies/Range (MeV) Typical currents int. (HA) Employed external 40 (HA) Hours per week machine is in operation (excluding maintenance): 40 Hours per week employed in radionuclide production: 25 3 2- Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 311 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) .per baton "C "N, 4 per week 1JN Hj'O week25per A "0 N3 week16per ISp HiSO (97%) 10 per week 1 «F ' 02 (97%) week4per enriched O2 recovery [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG, F-Fluorodopa, F-Fluoro-m-tyrosine, I8F-Fluoroacydovir, 18F-Fluoro-ethylspiperone, 18F- WIN "C-WIN, "C-Acetate, "C-Carbon Monoxide, N- Ammonia I5O-Water, 15O-Carbon Monoxide, I5O-Oxygen [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 6 engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 312 UNITED STATES OF AMERICA USA-7 [1] Institute: University of Southern California Postal Address: Pablo,1510n 0 Sa 35 # Angeles,Los 90033CA Telephone: 1-213-3421166 Fax/E-mail: 1-213-3425778; [email protected] [2] Person in-charge: Dr. Peter S. Conti (Title/Position) Director, PET Imaging & Radiological Resources Other senior staff: James R. Boding; Miar Alauddin; John Fissikis; Keith Higa; Betty Ku [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS111 Year: (i) of installation: 1990 (ii) of any major reconstruction [4] Particle beams available: * ft ~ • n I *& : ^He "He Dual Beams ,/ ,^ t , tf -- V-^jJ Beam energies/Range 11 (MeV) Typical currents int. 150 (HA) Employed external 20-40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 2 : Hours per week employed in radionuclide production: 75 Hours per week machine maintenance: 3 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 313 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N, 16.5 1 per month H O/EtOH 1.7 n"N 2 monthper 3 /}*T o N2 11.2 4 per month >« a y F H2' O (96%) 35 weekper 5 H2 O not recovered " IS F "02 15 monthper 1 F-F2 ] [6 Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: 'fp-FDG, 5O-Water, >5O-Oxygen, 15O-Carbon Monoxide, 15O-Carbon Dioxide 13N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? 18F-FDG daily [9] Is medical research/diagnosis carried out on site/off site? Both on & off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i . r[10a reactio] n cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thick target yields No Decay data No [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 314 UNITED STATES OF AMERICA USA-8 [1] Institute: PETNet / AltoVA Pah Postal Address: Nuclear Medicine Service (115) 3801 Miranda Ave Palo Alto, CA 94304 Telephone: 1-650-4962540 Fax/E-mail: 1-650-4962590 [2] Person in-charge: HenryDr. PadgettC. (Title/Position) Manager Other senior staff: Dave Wilson ] [3 Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1996 majoy an f (iir o )reconstructio n [4] Particle beams available: "H : /, «H JHe "He Dual Beams H". K* • s^s&i! s r • Beam energies/Range (MeV) 11 Typical currents int. (liA) Employed external 25-40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 5-15 Hour weer spe k employe radionuclidn di e production: 5-15 Hours per week machine maintenance: ~0 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: commericala Weare supplier 315 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 1J "AT H2O + EtOH ~j? ~ 0.5 per week As NH3 e •«F H2' O (97%) 3.7 weekper 2-3 As'*F a «F H2'*O (97%) 29-37 5 - 10 per week H2' O not recovered [6] Radionuclides planned to be produced in the near future: 15o [7] Major radiopharmaceuticals produced: T-FDG N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? 2-3 per week [9] Is medical research/diagnosis carried out on site/off site? Yes,siteOn If on site, indicate imaging devices available number *511KeVSPET 1 Gamm* a camera * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i r. [10 a reactio] n cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 316 UNITED STATE AMERICF SO A USA-9 ] [1 Institute: Northern California PET Imaging Centre Postal Address: 3195FolsomBlvd. Sacramento, 95816CA Telephone: 1-916-4556073 Fax/E-mail: [2] Person in-charge: Diana Tribey (Title/Position) Manager Other senior staff: Mason Jones [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1992 (ii) of any major reconstruction [4] Particle beams available: IH ; • -*m *He "He Dual Beams Beam energies/Range yes (MeV) 11 Typical currents int. (HA) Employed external 20-40 (HA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di 0 1 e production: 2 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 317 [5] Radionuchdes produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C "N 27 1 per year UN H O/EtOH n 2 ~ 3 1 per month o "N ~ 7 month1per S IS «F H2' 0 24 week10per H2 Onot recovered ] [6 Radionuchdes planne producee b o dneae t th rn di future : [7] Major radiopharmaceuticals produced: F-FDG N-Ammonia O-Water supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes yesf I , whic oftenw h ho one ?d san 18F-FDG monthper 1 [9] Is medical research/diagnosis carried out on site/off site? On site siten o f , I indicate imaging devices available number *511KeVSPET 1 * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 318 UNITED STATES OF AMERICA USA-10 [1] Institute: Yale University / VA PET Centre (115A) Postal Address: Campbell950 Avenue West Haven, CT06516 Telephone: 1-203-9374884 Fax/E-mail: garg@biomed. med-yale.edu [2] Person in-charge: Pradeep Garg (Title/Position) Director, Radiopharmaceutical Chemistry Other senior staff: [3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1990-91 majoy an (ii f r)o reconstructio n ] [4 Particle beams available: *He *He Dual Beams r *' * , r::C^\ !» V ?k'',j*-*$fy***-f ' " _ Beam energies/Range 11 (MeV) Typical currents int. (jiA) Employed external (»iA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 4 - 0 3 : Hours per week employed in radionuclide production: ~ 4 - 5 Hours per week machine maintenance: 0-10 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 319 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C 33 weekper 2-3 R&D n"N LI 10-20 weekper o I3N 4.4 6-20 per week <« S a F H2' O (>96%) 16.7 5 - 7 per week H2' O not recovered [6] Radionuclides planne producee b o neadt e th r n di future : [7] Major radiopharmaceuticals produced: F-FDG, F-Altanserine, -para-FluorobenzylguanidinesF I3N-Ammonia '5O-Water supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET 2 Gamm* a camera multiple * Single Photon Tomography (SPET) multiple * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections No Thico kN target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 320 UNITED STATES OF AMERICA USA-11 [I] Institute: Mount Sinai Medical Centre Postal Address: 4300 Alton Road Miami Beach, FL-33140 Telephone: 1-305-6742465 Fax/E-mail: 1-305-6742428 [2] Person in-charge: ThomasDr. SootheE. (Title/Position) Director, Cyclotron/Radiochemistry Other senior staff: Mike Plitnikes; Patricia Smith Manny Tavana [3] Type of cyclotron: PositiveIon Manufacturer: The Cyclotron Corporation Model: CS-30 Year: (i) of installation: 7972 (ii) of any major reconstruction: [4] Particle beams available: ''Jfc«., M ^H *He "He Dual Beams ijv Beam energies/Range Proprietary (MeV) Typical currents int (HA) Employed ext (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): Proprietary Hours per week employed in radionuclide production: Proprietary Hours per week machine maintenance: Proprietary Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Phy sics: Others: 321 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h 0/Ga oeZn Proprietary '"In luCd Proprietary ""77 ™n Proprietary ] [6 Radionuclides planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? K7Ga-chloride 111 In-chloride 201 Tl-chloride world wide medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 322 UNITED STATES OF AMERICA USA-12 [1] Institute: Joseph'sSt. Hospital Postal Address: 3003 Dr. Martin Luther King Jr. Blvd. Tampa, 33607FL Telephone: 1-813-8765620 Fax/E-mail: [2] Person in-charge: John Mother (Title/Position) Other senior staff: Kathie Krista, Mike Mosley John 'ConnenO [3 ] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1989 (ii) of any major reconstruction: ] [4 Particle beams available: 1ET •' *SL *He "He Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int (uA) Employet ex d 20-40 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 10 Hours per week employed in radionuclide production: 10 Hours per week machine maintenance: 2 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Phy sics: Others: 323 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "F Ja H2 O (97%) 16-27 5 per week ] [6 Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: 18T-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes yesf I , whic oftenw h ho one ?d san 18F-FDG 5 days per week medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 324 UNITED STATES OF AMERICA USA-13 [1] Institute: Emory University CentrePET Postal Address: 1364 Clifton Road Atlanta, GA 30322 Telephone: Fax/E-mail: 1-404-7127930 [2] Person in-charge: Mark Goodman (Title/Position) Other senior staff: Ronald Crowe ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1992 majoy an (iif r o )reconstructio n [4] Particle beams available: "He Dual Beams -;IH 3^ , . , *R* Beam energies/Range 11 yes (MeV) Typical currents int. (jiA) Employed external 20-40 (HA) Hours per week machine is in operation (excluding maintenance): 30 Hours per week employed in radionuclide production: 4 ~ Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 325 [5] Radionuclides produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch JSp "0, 8-10 week1per '«F-F3 "0 "N ~ 7 4-5 per week !SF S H2' O (97%) ~ 5 5 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: isT-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosi siten O s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomograph2 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 326 UNITED STATE AMERICF SO A USA-14 [1] Institute: Theragenics Corporation Postal Address: 5325 Oakbrook Parkway Norcross, GA 30093 Telephone: Fax/E-mail: 1-770-3818447 [2] Person in-charge: Tony Longo (Title/Position) Cyclotron Facility Manager Other senior staff: Tom West; Ty Robin; Joe Rodgers; J. Hwung [3] Typ cyclotronf eo : Negative Ion Manufacturer: ISA Model: Cyclone 18+ installationf Yearo ) (i : : 1992 majoy an (iif r o )reconstructio n [4] Particle beams available: Jta -.rf - ^ ' 'dJUt .v^Sg|fi ^ ''-,-•; ^ :: *B* Dual Seams " 1,4 Beam energies/Range 18 (MeV) Typical currents int. various (HA) Employed external n/a (HA) Hours per week machine is in operation (excluding maintenance): 144 to 168 Hours per week employed in radionuclide production: Hours per week machine maintenance: Typical 0-36 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 327 [5] Radionuchdes produced: Radionuclide Target Material Activit y (GBq) frequency Comments Produced (enrichment) -spgrlwtoaf•,ws,,^™ . i. » 5 IV3Pd Rh 10 to 60 1 per -week [6] Radionuchdes planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: 103Pd, Brachytherapy [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Medical; Typical 1 to 10 per month per client medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Some research on site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 328 UNITED STATES OF AMERICA USA-15 [1] Institute: Theragenics Corporation Postal Address: 5325 Oakbrook Parkway Norcross, GA 30093 Telephone: Fax/E-mail: 1-770-3818447 [2] Person in-charge: Tony Longo (Title/Position) Cyclotron Facility Manager Other senior staff: Tom West; Ty Robin; Joe Rodgers; J. Hwung [3] Typ cyclotronf eo : NegativeIon Manufacturer: IBA Model: Cyclone18+ Year: (i) of installation: 1994 (ii) of any major reconstruction [4] Particle beams available: * •; la *He iBe Dual Beams $>*'•-* Beam energies/Range 18 (MeV) Typical currents int. various (|1A) Employed external n/a (^A) Hours per week machine is in operation (excluding maintenance): 144 to 168 Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Typical 0-36 Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 329 [5] Radionuclides produced: Radionnclide Target Material Activity(GBq) Frequency Comments Produced (enrichment£ ) . perliatch iu*pd Rh 10 to 60 weekper 1 [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 103Pd, Brachytherapy supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, whic oftenw h ho one ?d san Medical; Typical 1 to 10 per month per client medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Some research on site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 330 UNITED STATE AMERICF SO A USA-16 [1] Institute: Theragenics Corporation Postal Address: 5325 Oakbrook Parkway Norcross, GA 30093 Telephone: Fax/E-mail: 1-770-381 8447 [2] Person in-charge: Tony Longo (Title/Position) Cyclotron Facility Manager Other senior staff: West; Robin;Tom Ty Rodgers;Joe HwungJ. [3] Typ cyclotronf eo : Negative Ion Manufacturer: IBA Model: Cyclone 18+ installationf Yearo ) (i : : 1996 majoy an (iif r o )reconstructio n [4] Particle beams available: l *'x H• *¥*!, j^a • --• ^He "He Dual Beams ^ 'SS "'".>'l- Beam energies/Range 18 (MeV) Typical currents int. various (HA) Employed external N/A (HA) Hour weer spe k machin operation i s ei n (excludin8 g maintenance)16 o t 4 14 : Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Typical 0-36 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 331 [5] Radionuclides produced: Radionaclide Target Material Activity (GBqr )pe Frequency Comments Produced (enrichment) batch t(JiPd Rh 60 10to 1 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 103Pd, Brachytherapy supplu yo o y D radionuclides/radiopharmaceutical[8] otheo t s r institutions? Yes yesf I , whic oftenw h ho one ?d san Medical; month per clientTypical10 per to 1 medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Some research on site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 332 UNITED STATE AMERICF SO A USA-17 [1] Institute: Theragenics Corporation Postal Address: 5325 Oakbrook Parkway Norcross, 30093GA Telephone: Fax/E-mail: 1-770-381 8447 [2] Person in-charge: Tony Longo (Title/Position) Cyclotron Facility Manager Other senior staff: Tom West; Ty Robin; Joe Rodgers, HwungJ. ] [3 Typ cyclotronf eo : NegativeIon Manufacturer: IBA Model: Cyclone18+ Year: (i) of installation: 1996 majory an (iif o )reconstructio n ] [4 Particle beams available: IH ,,::;* •• , *He ti Beam energies/P%ange 18 (MeV) Typical currents int. various (HA) Employed external N/A (HA) Hour weer spe k machin operation i s ei n (excludin8 g 16 maintenance) o t 4 14 : Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Typical 0-36 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 333 [5] Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ""Pd Rh 10 to 60 1 per week ] [6 Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: 103Pd, Brachytherapy [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Medical; Typical 1 to 10 per month per client medicas I ] l[9 research/diagnosis carrie site/ofn o t dou f site? Some research on site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 334 UNITED STATES OF AMERICA USA-18 [1] Institute: The Queens Medical Centre Postal Address: 1301 Punchbowl Street Honolulu, HI 96813 Telephone: 1-808-5377500 Fax/E-mail: 1-808-5377812; [email protected] [2] Person in-charge: Patrick McGuigan (Title/Position) Other senior staff: Nancy Chun ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS111 installationf Yearo ) (i : : 1998 majory an (lif o )reconstructio n [4] Particle beams available: H » " : ~ T "I £&*^Jo-Sf>%i ,^.rj - JSB *pM-. * i. f • ^e:; "He Dual Beams • - Y^j *( r , * * ' M ' Beam energies/Range (MeV) 11 Yes Typical currents int. (HA) Employed external (HA) Hours per week machine is in operation (excluding maintenance): Installation underway Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 335 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [6] Radionuclides planned to be produced in the near future: 18 [7] Major radiopharmaceuticals produced: Planned 18"'F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Planned If yes, whic oftenw h ho one ?d san Plan to supply 18FDGfor 511 KeVSPET at other medical Centres [9] Is medical research/diagnosis carrie site/ofn o t dou f site? Yes siten Ifo , indicate imaging devices available number KeVSPE1 51 * T Gamm* a camera 1 * Single Photon Tomography (SPET) 6 * Positron Emission Tomography (PET) 32 ring prototype engageu yo e nuclean di Ar r. a reactio[10] n cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 336 UNITED STATES OF AMERICA USA-19 [I] Institute: Medi-Physics, Inc. Postal Address: Amersham Healthcare 3350 Ridge Avenue Arlington Heights, 60004IL Telephone: 1-847-3988400 Fax/E-mail: [2] Person in-charge: Thomas Springer (Title/Position) Director of Operations Other senior staff: Brian Cams [3 ] Typ cyclotronf eo : Positive Ion, Variable Energy Manufacturer: Scanditronix Model: MC-40 installationf Yearo ) (i : : 1979 majoy an (iif ro ) reconstruction [4] Particle beams available: 'f^i^Xf, :", * y ^pSEI*^ T s s* m *,» "T-1 "'.,Si"3 , .\ *He - *He Dual Beams ^ *•* ^K°4 * % Beam energies/Range (MeV) Proprietary Typical currents int. (HA) Employed external (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): Proprietary information Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 337 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h Proprietary information [6] Radionuclides planne producee b o dneae t th rn d i future : Proprietary Information [7] Major radiopharmaceuticals produced: In 1, I 201- 1, ,123r 111, [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san Proprietary Information [9] Is medical research/diagnosis carried out on site/off site? No siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 338 UNITED STATES OF AMERICA USA-20 [1] Institute: Medi-Physics, Inc. Postal Address: Amersham Healthcare 3350. Ridge Avenue Arlington Heights, IL 60004 Telephone: 1-847-3988400 Fax/E-mail: [2] Person in-charge: Thomas Springer (Title/Position) Director of Operations Other senior staff: Brian Cams [3] Typ cyclotronf eo : Positive Ion, Variable Energy Manufacturer: SumitomoCGR & Model: PV-750 Year: (i) of installation: 1986 (ii) of any major reconstruction [4] Particle beams available: *H .:*. ^ *He *He Dual Beams Beam energies/Range Proprietary (MeV) Typical currents int. (HA) Employed external (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): Proprietary Information Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 339 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h Proprietary information ] [6 Radionuclides planne producee b o dneat e th r n di future : Proprietary Information [7] Major radiopharmaceuticals produced: 201 ~>n!23 tn, i, "'in/??/// [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Proprietary Information [9] Is medical research/diagnosis carried out on site/off site? Wo siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 340 UNITED STATE AMERICF SO A USA-21 [1] Institute: Medi-Physics, Inc. Postal Address: Amersham Healthcare 3350 Ridge Avenue Arlington Heights, IL 60004 Telephone: 1-847-3988400 Fax/E-mail: [2] Person in-charge: Thomas Springer (Title/Position) Director of Operations Other senior staff: Brian Cams [3] Type of cyclotron: Positive Ion, Variable Energy Manufacturer: Scanditronix Model: MC-40 Year: (i) of installation: 7979 (ii) of any major reconstruction [4] Particle beams available: IT•HT * ->~j "He Dual Beams r '« f-j-*J ** ' *H« •i - i A, •• B Beam energies/Range Proprietary (MeV) Typical currents int. GiA) Employed external (uA) Hours per week machine is in operation (excluding maintenance): Proprietary information Hours per week employed in radionuclide production: Hours per week machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 341 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch Proprietary information [6] Radionuclides planned to be produced in the near future: Proprietary Information \T\ Major radiopharmaceuticals produced: 2o,n mL y,1/n [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Proprietary Information [9] Is medical research/diagnosis carried out on site/off site? No siten o ,f I indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 342 UNITED STATES OF AMERICA USA-22 [I] Institute: Net Chicago- PET Postal Address: 200 E. Howard Street No: 240 DesPlaines,IL60018 Telephone: 1-847-2971322 Fax/E-mail: [2] Person in-charge: Russ Greenberg (Title/Position) Manager Other senior staff: Clyde Cole [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1995 (ii) of any major reconstruction [4] Particle beams available: *H• ;«:*:J^ *H ^fc "He Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int. (HA) Employed external 20-40 (uA) Hours per week machine is in operation (excluding maintenance): 10 Hour weer spe k employe radionuclidn di 0 1 e production: 1 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 343 ] [5 Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment r )batcpe h~ e "F H2' O (97%) -20 weekper 5 ] [6 Radionuclides planne producee b o neade t th rn d i future : ] [7 Major radiopharmaceuticals produced: 18T-FDG supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? 18T-FDG 5 times weekper medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 344 UNITED STATES OF AMERICA USA-23 [I] Institute: Methodist Medical Centre of Illinois Postal Address: 112 Crescent, Peoria Illinois 61606 Telephone: 1-309-6724191 Fax/E-mail: [2] Person in-charge: Danny Bingham (Title/Position) Manager Other senior staff: Brenda Shields [3] Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 7990 (ii) of any major reconstruction [4] Particle beams available: " •"'• w l 4 **• !._;»« .-If-'f^H ^Bfe He Dual Beams w tj& ' ' ^ * 3*I f Beam energies/Range 11 yes (MeV) Typical currents int. (HA) Employed external 20-40 GiA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 2 : Hours per week employed in radionuclide production: 20 5 0. Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 345 [5] Radionuclides produced: Radionuclide Target Materia: l Activity (GBq) Frequency Comments Produced (enrichineiit) : perHafcliJ:"" ' J "N ' c week1per <* F H2"0 weekper 5 [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 18T-FDG 5 per week medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 346 UNITED STATE AMERICF SO A USA-24 [1] Institute: Indiana University Cyclotron Facility Postal Address: 2401 Milo SampsonB. Lane Bloomington, IN 47408 Telephone: 1-812-8559365 Fax/E-mail: 1-812-8556645; @iucf.indiana.edu [2] Person in-charge: Dr. John M. Cameron (Title/Position) Director Other senior staff: M. Wedekind; W. Jacobs J. Collins [3] Type of cyclotron: Separated Sector Manufacturer: In-house Model: K200 installationf Yearo ) (i : : 1975 (ii) of any major reconstruction: [4] Particle beams available: JOT - - ; «TT- '**rrjdL 'HMM&e Dnal Beams Beam energies/Range 200 90 270 (MeV) Typical currents int 20 (uA) Employed ext 5 (HA) Hours per week machine is in operation (excluding maintenance): 160 Hours per week employed in radionuclide production: Occasionally Hour weer spe k machine maintenance: 8 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Injector to Cooled Beam Storage Ring 347 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch [6] Radionuclides planned to be produced in the near future: 124 [7] Maj or radiopharmaceuticals produced: Produced off-site supplu yo o yD radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? Indiana University Medical School, Department of Medicine medicas I ] l[9 research/diagnosis carrie site/ofn o t dou f site? Off site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurementss Ye ? . b Which typ nucleaf eo useu r dat?yo o ad Reaction cross sections Yes Thics kYe target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 348 UNITED STATES OF AMERICA USA-25 [1] Institute: Indiana University Cyclotron Facility Postal Address: 2401 Milo B. Sampson Lane Bloomington, IN47408 Telephone: 1-812-8559365 Fax/E-mail: 1-812-8556645; @iucf.indiana.edu [2] Person in-charge: Dr. John M. Cameron (Title/Position) Director Other senior staff: Wedekind;M. JacobsW. J. Collins [3 ] Type of cyclotron: Separated Sector Manufacturer: In-house Model: K16 Year: (i) of installation: 1972 majoy an f r(ii o reconstruction) : [4] Particle beams available: *nr ~*TVJi , JOL -- c £ '^ *He Ifie Dual _ $ Beams Beam energies/Range 3-16 (MeV) Typical currentt m s 50 (nA) Employet ex d 10 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 160 Hour weer spe k employe radionuchdn di e production: Occasionally Hour weer spe k machine maintenance: 8 Additional applications of the cyclotron: Injector to K200 Cyclotron Radiotherapy/Activation Analysis/Radiobiology/Physics: Others. 349 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 'Be 'Li various occasionally research [6] Radionuclides planne producee b o dneae t th rn di future : ] [7 Major radiopharmaceuticals produced: Produced off-site supplu yo o y D [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? Indiana University Medical School Purdue University medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Offsite siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i . r[10a reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 350 UNITED STATES OF AMERICA USA-26 [1] Institute: Indiana University Hospital Postal Address: 550 N. University Blvd. (UH 0028) Indianapolis 46202IN Telephone: 1-317-2743412 Fax/E-mail: 1-317-2743475 [2] Person in-charge: Bruce H. Mock (Title/Position) Associate Professor of Radiology Other senior staff: Gary Hutchias; G. Keith Mulholland [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS-112 Year: (i) of installation: 1992 (ii) of any major reconstruction: [4] Particle beams available: H H 'He ''He Baal Beams . * :-m r- " Beam energies/Range 11 yes (MeV) Typical currentt in s n/a (uA) Employet ex d 20-40 (HA) Hours per week machine is in operation (excluding maintenance): 50 Hour weer spe k employe radionuclidn di e production: 75 Hour weer spe k machine maintenance: 5 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 351 [5] Radionuclides produced: Radionuclide Target Material Artivity(GBq) Frequency Comments Produced (enrichment) batcr pe h "C "N, 35 week15per n"N H2O 2 4 per week o "N2 (>98%) 8 week20per ISp- H?SO (>90%) 21 8 per week ] [6 Radionuclides planne producee b neao de t th rn di future : [7] Major radiopharmaceuticals produced: 18F-FDG "C-Acetate, "C-Hydroxy Ephedrine !5O-Water 13N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? If yes, which ones and how often? 18F-Fluoride 1-10 times per month [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET 2 * Gamma camera 4 * Single Photon Tomography (SPET) 9 Positro* n Emission Tomography (PET) 2 engageu yo e nuclean dAr i [10 r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 352 UNITED STATE AMERICF SO A USA-27 [1] Institute: University of Iowa Postal Address: PET Imaging Centre Iowa City, 52242IA Telephone: 1-319-3564100 Fax/E-mail: 1-319-3536512; richard-hichwa@uiowa. edu ] [2 Person in-charge: Prof. Richard HichwaD. (Title/Position) Director Other senior staff: G. Leonard Watkins; Laura Boles Ponto Mark T. Madsen [3] Type of cyclotron: Positive Ion, Sector-focused, Resistive Magnet Manufacturer: Scanditronix Model: MC-17F installationf Yearo ) (i : : 1990 (ii) of any major reconstruction: Redesign of software display controland Replacement of manual operations with fully automated functions [4] Particle beams available: : -- *H •' v ;^ ->: 'He .h*He , Dual Beams • .« Beam energies/Range 18 (fixed7.3 (MeV) energy) Typical currents int 1-70 1-70 (uA) Employet ex d 25-50 10-15 (HA) 100 max 100 max Hour weer spe k machin operation i s ei n (excluding maintenance)0 4 > : Hours per week employed in radionuclide production: 20 - 30 Hours per week machine maintenance: < 1 target maintenance yearper 1 Additional applications of the cyclotron: We produce radioactive sources for various detector experiments in conjunction with the high energy physics group Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 353 [5] Radionuclides produced: Radionuclide Target Material Activity-' Frequency Comments Produced (enrichment) (GBq)per batch 14 n"C N2 (+0.1 %Oi) 92.5 1-2weekper o "N, (+1%O2) 7.4 5-7 per week <* a F H2 O (97%) 22 5 per week H2' O recovered 4Sy na'Ti 0.37 1 per week PIN sourceto replace f&Ge] in tomograph [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: I8F-FDG I5O-Oxygen 15O-Water, 15O-Carbon Monoxide, ISO-Carbon Dioxide "C-Methionine, "C-Acetate, " C-Carbon Monoxide, "C-Carbon Dioxide, C- receptor ligands of various types [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? Not at present. We are considering delivery of ' F-FDG to other hospitals. Much depends positivea on financial analysis of this operation, and PDA (US federal government food and drug administration) approval ofFDGfor routine clinical imaging [9] Is medical research/diagnosis carried out on site/off site? Medical These activities occur siteon research/ diagnosis siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thics kYe target yields o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 354 UNITED STATES OF AMERICA USA-28 [I] Institute: Massachusetts General Hospital Postal Address: Department of Radiology Boston, MA 02114 Telephone: 1-617-7268336 Fax/E-mail: 1-617-7265123; [email protected] [2] Person in-charge: John CorreiaA. (Title/Position) Other senior staff: John Babich; Eli Livni Alan Fishman [3] Typ cyclotronf eo : Positive Ion Manufacturer: Scanditronix Model: MC-17F installationf Yearo ) (i : : 1989 (ii) of any major reconstruction: Older Allis Chalmers Cyclotron Replaced in 1989 [4] Particle beams available: lfl 1H" "He "He Dual Beams L. •-.*".'* ,- : Beam energies/Range 18 8.5 (MeV) Typical currents int (uA) Employet ex d 15-50 (uA) Hours per week machine is in operation (excluding maintenance): 40 Hours per week employed in radionuclide production: 34 6 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others 355 [5] Radionuclides produced: Radionuclide Target Material Activity [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG !3 IS I3 N2F , N-Ammonia I5O- Water, l5O-Oxygen, '5O-Carbon Dioxide C receptor ligands 18Preceptor ligands [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? Yes,On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 356 UNITED STATES OF AMERICA USA-29 [1] Institute: Johns Hopkins Medical Institutions Postal Address: Division of Nuclear Medicine PET Center 600 North Wolfe Street, Tower Bl-167 Baltimore, MD 21287-0816 Telephone: 1-410-9552916 Fax/E-mail: 1-410-9550691; robert-dannals@tracer. nm.jhu.edu [2] Person in-charge: RobertDr. DannalsF. (Title/Position) Other senior staff: Hoyden T. Raven; John L. Musachio William MathewsB. [3] Typ cyclotronf eo : Positive Ion Manufacturer: Scanditronix Model: RNP-16 installationf Yearo ) (i : : 1981 majoy an (ii f r) o reconstruction : [4] Particle beams available: *H *K *He "He Dual Beams Beam energies/Range 16 \ 8 (MeV) Typical currentt in s 100 50 (UA) Employed ext 50 25 (HA) Hours per week machine is in operation (excluding maintenance): 60 Hours per week employed in radionuclide production: 20 Hours per week machine maintenance: 4 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 357 ] [5 Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch I4 n"C N 40 5 per day o "N/02 8 10 per week >«F 8 2 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: "C-Carfertanil, "C-McN5652, "C-Raclopride, "C-WIN 35,428 15 O water 18FFDG supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? Yes If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) 5 * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 358 UNITED STATE AMERICF SO A USA-30 [1] Institute: National Institute of Drug Abuse (NIDA) Postal Address: Brain Imaging Centre 5500 Nathan Shock Drive Baltimore, 21224MD Telephone: 1-410-5502911 Fax/E-mail: 1-410-5501441/5502914 [2] Person in-charge: EdytheDr. LondonD. (Title/Position) Director Other senior staff: Jonathan Links; Andrew Horti; Lloyd Weyl; Varughese Kurian; Morgan Stratton; Jeffrey Banta [3] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS111 installationf Yearo ) (i : : 1997 majoy an (ii f r) o reconstructio n [4] Particle beams available: * ; £ . H * '•'•r-'-^ar. -... *me "He Daal Beams Beam energies/Range ;/ (MeV) Typical currents int. (uA) Employed external 50 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): Installation underway Hours per week employed in radionuclide production: Hours per week machine maintenance: Additional application cyclotrone th f so : Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: Radiochemistry labs under construction 359 [5] Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch Jt> "C "N2+ 2.5% O3 "0 "AM- 2.5% '"Oj "F H2 O (>96%) i»P Ia 02 (96%) ] [6 Radionuclides planne producee b neao de t th r n di future : listedAs above [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 360 UNITED STATE AMERICF SO A USA-31 [1] Institute: National Institute of Health Postal Address: Bldg. 10, Rm 1C401, MSC1180 Bethesda, 20892MD Telephone: 1-301-4960345 Fax/E-mail: 1-301-4023521; paul@nmdhst. nih.govcc. [2] Person in-charge: William Eckelman (Title/Position) ChiefDepartmentPET Other senior staff: Paul PlascjakS. [3] Type of cyclotron: Fixed Energy Compact Manufacturer: The Cyclotron Corporation Model: CS30 Year: (i) of installation: 1985 majoy an (ii f r)o reconstruction: [4] Particle beams available: ' [ jB «?7 "He *He Dual Beams '": :,-;*"•! Beam energies/Range 26.5 14.8 38.1 29.6 (MeV) Typical currentt in s 200 300 135 90 (HA) Employed ext 60 100 60 40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 72 6 days per week Hours per week employed in radionuclide production: hours5 3 r radionuclide~ fo production Hour weer spe k machine maintenance: 4 Additional applications of the cyclotron: Cyclotrons used primarily radionuclidePET for production Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 361 [5] Radionuclides produced: Radionnclide Target Activity (GBq) 7 Frequency Comments Produced Material batcr pe h (enrichment) "C ^2 3-75 2-6 per week "N H2O 1-2 3-5 per week '=0 N2 ~ 1/min day per 2-3 ISp Ne 1-15 2-5 per week «F "O (95%) 15-30 2-3 per week '"At Bi 0.5-1.5 weekper 3 ~ [6] Radionuclides planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: 15O-Water *F-DOPA, I8F-FPrTZTP, ISF-FDG 13N-Ammonia 1' C-Raclopride, 6-'8F-Cydofoxy, "C-Palmitic Acid, C-Arachidonic" acid supplu yo o y D [8radionuclides/radiopharmaceutical] otheo st r institutions? yesf I , whic oftenw h oneho ?d san 18FDG provided centreweek1 per to 1 [9] Is medical research/diagnosis carried out on site/off site? Yes Research/ diagnosis on site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomograph3 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 362 UNITED STATES OF AMERICA USA-32 [I] Institute: National Institute of Health Postal Address: Bldg. 10, Rm 1C401, MSC1180 Bethesda, 20892MD Telephone: 1-301-4960345 Fax/E-mail: 1-301-4023521; [email protected] [2] Person in-charge: William Eckelman (Title/Position) Chief,DepartmentPET Other senior staff: Paul S. Plascjak [3] Type of cyclotron: Fixed Energy Compact Manufacturer: Japan Steel Works Ltd. Model: JSW-1710 Year: (i) of installation: 1985 (ii) of any major reconstruction: [4] Particle beams available: 1H *He *He Dual Beams ** Beam energies/Range 77.5 9.8 (MeV) Typical currents int 150 150 (HA) Employed ext 50 50 (UA) Hour weer spe k machin operation i s ei n (excluding maintenance): 72 6 days per week Hours per week employed in radionuclide production: -35 Hour weer spe k machine maintenance: 4 Additional applications of the cyclotron: Cyclotrons used primarily for PET radionuclide production Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 363 [5] Radionuchdes produced: Radionuclide Target Material Comments Produced »^* fV C 3-75 2-6weekper N H20 1-2 3-5 per week 0 ~ 1/min 2-3 per day Ne 1-15 2-5weekper 15-30 2-3weekper [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: !5O-Water 6-'8F-DOPA, 6-'8F-dopamine, 18F-FPrTZTP, I8F-FDG N-Ammonia C-Raclopride, 6-'18aF-Cyclofoxy, 11"C-Palmitic Acid, 11,"C-Arachidonic acid supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? If yes, whic oftenw h ho one ?d san 18FFDG provided centre1 weekto per 1 medicas I [9] l research/diagnosi siten O s carriesite/ofn o t dou f site? siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 3 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? No 364 UNITED STATE AMERICF SO A USA-33 [1] Institute: University of Michigan Postal Address: 3480 Kresge III Arbor, Ann 48109-0552MI Telephone: 1-313-7639244 Fax/E-mail: 1-313-7640288 [2] Person in-charge: Prof. Michael KilbournR. (Title/Position) Director, ChemistryPET Other senior staff: RobertDr. Koeppe Mr. James Moskwa [3] Typ cyclotronf eo : Medical Manufacturer: The Cyclotron Corporation Model: CS-30 installationf Yearo ) (i : : 1982 (n) of any major reconstruction: [4] Particle beams available: in "> *•:• H i. %r *He "He Dual Beams , , -i fev-s;r*^ „.,. .^Jkfc.tw^.1 - Beam energies/Range 26.0 75.0 38.0 30.0 (MeV) Typical currents int 200 300 100 90 (uA) Employet ex d 30 30 50 40 (nA) Hours per week machine is in operation (excluding maintenance): 15 Hours per week employed in radionuclide production: 12 4 Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 365 [5] Radionuchdes produced: Radionuclide Target Material ..-&*** Frequency Comments Produced ('-t«MStital!*SBft.I| !|?j(S6f«i)|»r •X":iatd» "C "tf, 90 25 per week n"N "0 12 weekper 10 > o '60 12 weekper 30 > >«F S H2' O (90-97%) 15 5 per week "Zn Zn < 1 weekper 2 [6] Radionuchdes planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18 j ''' C-Epinephrine, C-Pseudophedrine," C-Dihydiotetabenazine" 1'C-Acetate, C-N-methylpiperidinylbenzilate,'' ''C-Cartentanil "C-Flumazenil (FMZ), flC-Raclopride, '' C-Hydroxyephedrine (HED) 15O-Water I3N-Ammonia [8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis earned out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 3 [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 366 UNITED STATES OF AMERICA USA-34 [I] Institute: Gershenson Radiation Oncology Centre Postal Address: Harper Hospital Wayneand State University 3990 JohnR Detroit, MI 48201 Telephone: 1-313-7452487 Fax/E-mail: 1-313- 7452314; maughanr@kci. wayne. edu [2] Person m-charge: Dr. Richard L. Maughan (Title/Position) Other senior staff: [3] Type of cyclotron: MeVDeuteron50 Superconducting Cyclotron Manufacturer: Michigan State University Model: KlOO-Harper installationf Yearo ) (i : : 1990 majoy an (ii f r) o reconstruction : [4] Particle beams available: 1H ", : ^H *He *He Dual Beams ,r i Beam energies/Range 48.5 (MeV) Typical currentt in s 15 (uA) Employet ex d internal Be (uA) • target Hour weer spe k machin operation i s ei n (excluding maintenance): -60 Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: scheduledno maintenance during day Additional application cyclotrone th f so : Radiotherapy Neutrons- Radiobiology and Physics studies for neutron radiation therapy boronand neutron capture enhanced fast neutron therapy Radiotherapy/Activation Analysis/Radiobiology/Physics: We are making neutron spectrum measurements Others: 367 ] [5 Radionuclides produced: Radionnclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosio N s carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean di Ar r[10. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 368 UNITED STATE AMERICF SO A USA-35 ] [1 Institute: Childrens Hospital of Michigan Postal Address: CenterPET 3901 Beaubien Blvd. Detroit, MI 48201 Telephone: 1-313-9932618 Fax/E-mail: 1-313-9933845; [email protected] [2] Person in-charge: Dr. Harry T. Chugani (Title/Position) Director, CenterPET Other senior staff: Thomas Mangner,J. Otto Muzik, Diane Chugani, Marcel DiCarli, Dulak Chakraborty [3 ] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS-112 Year: (i) of installation: 1993 (ii) of any major reconstruction: [4] Particle beams available: *H *H 'He "He Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int 100 (HA) Employed ext 20-40 (UA) Hour weer spe k machin operation i s ei n (excluding maintenance)0 4 : Hour weer spe k employe radionuclid4 n di 2 - 0 2 e production: 4 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: 369 [5] Radionuclides produced: Radionaclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch "C "N2+l%'°02 60 5-10 per week "N H2'"0 1-2.5 5-10weekper n JO o "N2 (99%) + O2 1-3.5 10-15 weekper <* S F H2' 0 23 4-5 per week [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: '°F-FDG I5O-Water I3N-Ammonia "C-Acetate, " C-Flumazenil, '' C-m-Hydroxyephedrine (RED), 2- n C-Thymidine, "C-a-Methyl-L-Tryptophane [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No yesf I , whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? No If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera Singl* e Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 370 UNITED STATES OF AMERICA USA-36 ] [1 Institute: National Superconducting Cyclotron Laboratory Postal Address: Michigan State University South Shaw Lane EastLansing, MI 48824-1321 Telephone: 1-517-3559671 Fax/E-mail: 1-517-3535967 [2] Person in-charge: Dr. C.-K. Gelbke (Title/Position) Director Other senior staff: Peter S. Miller [3] Type of cyclotron: Superconducting Magnet Cyclotron Manufacturer: In-house Model: installationf Yearo ) (i : : 1977-1981 majoy an (iif ro ) reconstruction: 1996-1998 [4] Particle beams available: *16O MeV/nucleon,4+15 >29Xe22+ 10 MeV/nucleon examplefor 1JH 1H ^Be *He Dual Beams Beam energies/Range (MeV) Typical currents int (HA) Employet ex d (uA) * Bending limit 520q2/A2 MeV/nucleon Focusing limit 160 q/A MeV/nucleon Hours per week machine is in operation (excluding maintenance): Under reconstruction Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Injectior 1200to Cyclotron Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 371 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: Radiopharmaceutical Production plannednot is supplu yo o y D [8radionuclides/radiopharmaceutical] otheo st r institutions? No If yes, whic oftenw h ho one ?d san medicas I [9] l research/diagnosis carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 372 UNITED STATE AMERICF SO A USA-37 [1] Institute: National Superconducting Cyclotron Laboratory Postal Address: Michigan State University South Shaw Lane EastLansing, 48824-1321MI Telephone: 1-517-3559671 Fax/E-mail: 1-517-3535967 [2] Person in-charge: Dr. C.-K. Gelbke (Title/Position) Director Other senior staff: Peter MillerS. [3] Typ cyclotronf eo : Superconducting Magnet Cyclotron Manufacturer: In-house Model: Year: (i) of installation: 1980-1987 majoy an f (iir o reconstruction) : 1996-1998 [4] Particle beams available: * Any stable isotope A>2 , -.'i,%T ,'AySn : - «^^^' ^" s J lifjteflli f-s. afe J *He Dual Beams %•« « *. , *EiS~||O < £j* ~ r f " i ^flw~ • j PJf^NiKrTp' 'i Beam energies/Range (MeV) Typical currents int (uA) Employet ex d (uA) * Bending limit 1200 q2/A2 MeV/nucleon Focusing limit 400 q/A MeV/nucleon Hour weer spe k machin operation i s ei n (excluding maintenance)6 15 : Hours per week employed in radionuclide production: 2 1 Hour weer spe k machine maintenance: Additional applications of the cyclotron: Production of radioactive nuclear beams nuclearby fragmentation process Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 373 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "Li(700MeV) Be 2500 part./sec 2VMg(1300MeV) Be part./sec3.5 4UCl (2200 MeV) Be 1.6x1part/sec06 [6] Radionuclides planned to be produced in the near future: 36Ca, 56Ni [7] Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? We supply beams ofradionudides users,to many from other institutions [9] Is medical research/diagnosis carried out on site/off site? If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean di Ar [10r. a reactio] n cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 374 UNITED STATE AMERICF SO A USA-38 [I] Institute: William Beaumont Hospital Postal Address: 3601 West] Mile3 Road Royal Oak, MI 48083 Telephone: 1-248-5511211 Fax/E-mail: 1-248-5510768 [2] Person m-charge: Dr. Ram B. Sharma (Title/Position) Other senior staff: [3] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 (ii) of any major reconstruction ] [4 Particle beams available: ^ert ,.j $?.;* - 'Be *He Dual Beams f * •/,1 Beam energies/Range 11 yes (MeV) Typical currents int. 20-40 (uA) Employed external 20-40 (uA) Hours per week machine is in operation (excluding maintenance): 10 -15 Hour weer spe k employe radionuclidn d5 i -1 0 1 e production: Hours per week machine maintenance: 2-4 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 375 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) .per batch "C "N, 10 0-2 per week U H nN MeOH+ O 2 1 weekper 10 5- o "N2:02 (39:1) 7 weekper 5 1 10- ie >«F H2 O (97) 16 week5per [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: F-FDG ]N-Ammonia C-Acetate O- Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number 1 *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomograph/ y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo o N ? 376 UNITED STATE AMERICF SO A USA-39 [I] Institute: VA Medical Centre (IIP) Postal Address: 1 Veterans Drive Minneapolis, MN 55417 Telephone: 1-612-7252230 Fax/E-mail: 1-612-725-2068 [2] Person in-charge: Dr. D. Rottenberg (Title/Position) Director Other senior staff: Munawwar Sajjad; Rashid Syed Carroll Arnett; E. Akgun [3] Type of cyclotron: Positive Ion Manufacturer: Scanditronix Model: MC-40 Year: (i) of installation: 1985 (ii) of any major reconstruction: [4] Particle beams available: ', , ,*qr Vfe- •&• >tf «t |>3Q. ' -t --• <&&, "He Dual Beams •f-"*^*ldssls"i -IT ^. _\ :, - " ' Beam energies/Range 40 20 (MeV) Typical currentt in s (uA) Employed ext 25 35 (uA) Hours per week machine is in operation (excluding maintenance): 32 Hours per week employed in radionuclide production: 32 Hours per week machine maintenance: 6 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 377 [5] Radionuclides produced: Radionnclide Target Material ^Activity Frequency Comments Produced (enrichment) (GBq)per batch "C '% 11.0 / per week "N H2'°0 2.0 4 per "week A "0 N3 18.5 50 per week y IS "F H2' O (97%) 15.0 weel4per H2 0 recovered JU\r '«F Ne 11.0 1 per week [6] Radionuclides planne producee b neao de t th rn d i future : [7] Major radiopharmaceuticals produced: I8F-FDG, F-DOPA, I8F-Fluorobenzytrozomicol N-Ammonia 'O-water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? yesf I , whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged m nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 378 UNITED STATE AMERICF SO A USA-40 [1] Institute: Saint Louis University Hospital Postal Address: PET Imaging Department 3635 Vista Avenue Louis, St. 63110MO Telephone: 1-314-5778801 Fax/E-mail: 1-314-2685486 [2] Person m-charge: Dr. Ranajit K. Bera (Title/Position) Assistant Professor Other senior staff: Val Lowe; James W. Fletcher [3] Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 majoy an (iif r o )reconstructio n [4] Particle beams available: *H ^H 'He «He Dual Beams &>*••-• Beam energies/Range 11 (MeV) Typical currents int. ("A) Employed external 20-40 GiA) Hours per week machine is in operation (excluding maintenance): 36 Hour weer spe k employe radionuclidn di 3 1 e production: 5 1. Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 379 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h li "N c ; week4per 1JC Recovered "0 "N2 10 4 per month •«F S y H2' O (>95%) 30 8-10 weekper H2' O Recovery [6] Radionuclides planned to be produced in the near future: "c [1] Major radiopharmaceuticals produced: F-FDG, O-Water 'N- Ammonia supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 380 UNITED STATES OF AMERICA USA-41 [1] Institute: Creighton University Postal Address: PET Center 901 Dorcas Street Omaha, 88106NE Telephone: 1-403-3464181 Fax/E-mail: [2] Person in-charge: Marc Wrichelt (Title/Position) Manager Other senior staff: Steve Torres [3] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1989 (ii) of any major reconstruction: [4] Particle beams available: *H '• *H *He 'fce Dual Beams Beam energies/Range 11 yes (MeV) Typical currents int (uA) Employet ex d 20-40 (uA) Hours per week machine is in operation (excluding maintenance): Hour weer spe k employe radionuclidn di e production: Hours per week machine maintenance: Additional application cyclotrone th f so : P^adiotherapy/Activation Analysis/Radiobiology/Physics: Others: 381 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) • iper batch ISp JS H2 O 13 5 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: 18F-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? 18F-FDG medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 382 UNITED STATE AMERICF SO A USA-42 [1] Institute: Medi-Physics, Inc. Postal Address: Amersham Healthcare 900 Durham Ave. South Plainfield, NJ 07080 Telephone: 1-908-7570500 Fax/E-mail: [2] Person in-charge: Gordon Glass (Title/Position) Site Administration Manager Other senior staff: William McClain [3] Type of cyclotron: Positive Ion, Azimuthally Varying Field, Isochronous Manufacturer: The Cyclotron Corporation Model: CS-22 installationf Yearo ) (i : : 7973 (ii) of any major reconstruction [4] Particle beams available: *H .asj- C3JJS la* "He Dual Beams <{* >>,> £"£?T **! Beam energies/Range Proprietary (MeV) Typical currents int. (jiA) Employed external (uA) Hours per week machine is in operation (excluding maintenance): Proprietary information Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 383 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch Proprietary information [6] Radionuclides planned to be produced in the near future: Proprietary Information [7] Major radiopharmaceuticals produced: 6iGa 20!Tl 8IRb supplu yo o y D radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes yesf I , whic oftenw h ho one ?d san Proprietary Information [9] Is medical research/diagnosis carried out on site/off site? No siten o f , I indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 384 UNITED STATES OF AMERICA USA-43 [1] Institute: Medi-Physics,Inc. Postal Address: Amersham Healthcare 900 Durham Avenue South Plainfield, 07080NJ Telephone: 1-908-7570500 Fax/E-mail: [2] Person in-charge: Gordon Glass (Title/Position) Site Administration Manager Other senior staff: Willian McClain [3 ] Type of cyclotron: Negative Ion, Fixed Field, Fixed Frequency Variable Energy Manufacturer: IBA Model: Cyclone 30 installationf Yearo ) (i : : 1989 (ii) of any major reconstruction ] [4 Particle beams available: *H * > >.3tt "He %e Dual Beams Beam energies/Range Proprietary (MeV) Typical currents int. (uA) Employed external (HA) Hours per week machine is in operation (excluding maintenance): Proprietary information Hours per week employed in radionuclide production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analy sis/Radiobiology/Physics: Others: 385 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Freqaency Comments Produced (enrichment) per batch proprietary information [6] Radionuclides planne producee b o dneat e th r n di future : Proprietary Information [7] Major radiopharmaceuticals produced: 67--Ga, 20, Rb [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Proprietary Information [9] Is medical research/diagnosis carried out on site/off site? No siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 386 UNITED STATES OF AMERICA USA-44 [1] Institute: Columbia Presbyterian Medical Centre Postal Address: Milstein Hospital Building 622 W. 168th Street New York, NY 10032 Telephone: 1-212-3058815 Fax/E-mail: [2] Person in-charge: Jerry Strugala (Title/Position) Manager Other senior staff: Tom Boland; Michael Sanfilippo [3 ] Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1992 majory an (ii f ) o reconstruction ] [4 Particle beams available: IH J j-?"-•• - ;•'• ,1 nHr *Efe Hours per week machine is in operation (excluding maintenance): 25 Hours per week employed in radionuclide production: 25 Hours per week machine maintenance: ~ 1 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 387 [5] Radionuclides produced: Radionuclide Target Material Activity ,, Frequency Comments Produced (enrichment) | -igSttgdqat ,i.i s*s.lWfei* • ! !• v w l "C "N 37 5-7 per week "N H2O/EtOH -2.2 week1per "0 "N -7.4 15 per week >« S F H2' O (97%) -30 week2per [6] Radionuclides planne producee b o neade t th rn di future : [7] Major radiopharmaceuticals produced: F-FDG N-Ammonia C-Methionine O-Water supplu yo o yD [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? 18FFDG to 15 external institutions 5 times per week [9] Is medical research/diagnosis carried out on site/off site? Both If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph1 y (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 388 UNITED STATE AMERICF SO A USA-45 [1] Institute: North Shore University Hospital Postal Address: Research Department Cyclotron- /PETFacility Community350 Drive Manhasett,NY11021 Telephone: 1-516-5621055 Fax/E-mail: 1-516-5621120; [email protected] [2] Person m-charge: Dr. RobertJ. Dahl (Title/Position) Other senior staff: Thomas Chaly [3] Typ cyclotronf eo : Positive Ion Manufacturer: Scanditronix Model: MC-17F Year: (i) of installation: 7957 (ii) of any major reconstruction [4] Particle beams available: *H :, ^[ *He *He Dual Beams , 4- Beam energies/Range 17.5 5.75 77.5 (MeV) Planned Typical currents int. 180 180 (HA) Employed external 30-40 30-40 (HA) Hours per week machine is in operation (excluding maintenance) target: on 20 av. Hour weer spe k employe radionuclidn di e production: av.20 Hour weer spe k machine maintenance: 4 plus 2\veeks each year for periodic maintanence Additional application cyclotrone th f so : Radionuclide Production Development Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 389 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N2 + 0.1%O2 50 week2per "N H2'"O (natural) 2-3 occasionally "0 N2 + 1%H2 run 15per 2 per week " F H%) 2 '*O(96 33 week4per recoveredHO 2 ISp Ne 0.3%F+ 2 11 week1per >*F-F2 [6] Radionuclides planne producee b o neade t th rn d i future : [7] Major radiopharmaceuticals produced: 1SFDG, I8F-6-FDOPA,'8F-$-CIT, 1SF-OMD, 18F-Dopamine, C-Raclopride 'O-Water N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, whic oftenw h ho one ?d san Only to research collaborators with continuing joint projects [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gramma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a reactio[10] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 390 UNITED STATE AMERICF SO A USA-46 [1] Institute: State University of New York at Buffalo Postal Address: Department of Nuclear Medicine 105 Parker Hall 3435 Main Street Buffalo, 14214-3007NY Telephone: 1-716-8385889 Fax/E-mail: 1-716-8384918; fred@nucmed. buffalo,edu [2] Person in-charge: Robert E. Ackerhalt (Title/Position) Chairman & Director of the Cyclotron Facility Other senior staff: Michael HakaS. [3] Type of cyclotron: NegativeIon Manufacturer: IBA Model: Cyclone30 installationf Yearo ) (i : : 7992 (ii) of any major reconstruction: [4] Particle beams available: *H *H 'He «He Dual Beams f i t uf t. c 1 *. Beam energies/Range 15-30 (MeV) Typical currentt in s 0-450 (uA) Employet ex d (HA) Hours per week machine is in operation (excluding maintenance): 8 typical /164 available Hour r weespe k employe radionuclidn di e production: 8 typical Hour weer spe k machine maintenance: ~4 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: PET Isotopes 391 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N2 118 1 per week "N H2'°0(I) 7.5 - 15 1-2 per week in target "0 H2'°0(g) 23 1-2 per week each run = 7 doses >« S F H2' O (96%) 23 4-5 per week enriched water recovery "Cu, "Zn OJ'"Cu 966 weekper I [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: F-FDG N-Ammonia O- Water O-Carbon Dioxide [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, whic oftenw h ho one ?d san 'F-FDGVA daily N Ammonia weekly 'F-FDG MFH-3-4 times/week Roswell Iper week Biomedical Research weekper 1-2 medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Off site siten Ifo , indicate imaging devices available number *511KeVSPET 1 Gamm* a camera 15 * Single Photon Tomography (SPET) 22 * Positron Emission Tomography (PET) 3 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 392 UNITED STATE AMERICF SO A USA-47 [1] Institute: Memorial Sloan-Kettering Cancer Centre Postal Address: 1275 York Avenue New York, NY10021 Telephone: 1-212-6397398 Fax/E-mail: 1-212-7173263 ] [2 Person in-charge: Ronald Finn (Title/Position) Director, Cyclotron Facility Other senior staff: Yiauchung Sheh Vincent Bui [3] Type of cyclotron: Isochronous, Aximuthally Varying-Field, PositiveIon Manufacturer: The Cyclotron Corporation Model: CS-15 Year: (i) of installation: 1967 majoy an f ro reconstruction) (n : 1988-90, replacement of main magnet coils; replacement of target station ] [4 Particle beams available: JH ', J J^~% , *B* Dual Beams < "rf j| K '„!*"? ^ r«" Beam energies/Range 14.7 7.9 23.2 15.0 (MeV) Typical currents mt > 100 > 125 > 120 > 100 (uA) Employed ext 15-20 20-30 5-15 10 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 4 days Hours per week employed m radionuclide production: Research clinical days3/1 Hour weer spe k machine maintenance: 0.5 day Additional applications of the cyclotron: Nuclear medicine support and research Radiotherapy/Activation Analysis/Radiobiology/Physics: Others. 393 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h "C N2 7.4 1-2weekper "0 N2 0.1 0.5 day per week "F (96%)HfO 7.4 4-6 per week °°Ga "lZn (90%0 as required «(>Y e°Sr (95%) as required [61 Radionuclides planned to be produced in the near future: 94mTc,V 48 [7] Major radiopharmaceuticals produced: \F-FDG 'O- Water C-Methionine Numerous radiolabelled monoclonal antibodies supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? Collaborative research programmes only [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET 1MCD * Gamma camera 2 * Single Photon Tomography (SPET) 5 (+MCD) * Positron Emission Tomography (PET) 1 engageu yo e nuclean dAr i [10. r a reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 394 UNITED STATES OF AMERICA USA-48 [1] Institute: Brookhaven National Laboratory Postal Address: Chemistry Department, Bldg. 901 Upton, 11973NY Telephone: 1-516-344-4397 Fax/E-mail: 1-516-344-7902; [email protected] [2] Person in-charge: Dr. J.S. Fowler A.P.Dr. Wolf (Title/Position) Co-Director Co-Director Other senior staff: [3] Typ cyclotronf eo : Positive Ion Manufacturer: BNL Model: 60" Year: (i) of installation: 1960 (ii) of any major reconstruction: [4] Particle beams available: ?i?ff.*'?,^Js , ..,„ .,„ , & 4*lNte<'«'*t «, 3H£;>>k %« Dual Beams .,,VI , ,J l^-fa" * I , i s ^* Beam energies/Range 34 23 56 46 (MeV) Typical currentt in s 300 300 200 200 (uA) Employed ext 25 20 10 10 (uA) Hours per week machine is in operation (excluding maintenance): 1500 fiA-h on target in 1994 Hours per week employed in radionuclide production: Hours per week machine maintenance: Additional application cyclotrone th f so : Development 5% IsotopePET Production5% Radiotherapy/Activation Analysis/Radiobiology/Physics : Others: Basic research 95% in house / 5% external 395 [5] Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? If yes, whic oftenw h ho one ?d san medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 396 UNITED STATE AMERICF SO A USA-49 [1] Institute: Brookhaven National Laboratory Postal Address: Chemistry Department, Bldg.901 Upton, 1973mi Telephone: 1-516-344-4397 Fax/E-mail: 1-516-344-7902; [email protected] [2] Person in-charge: J.S.Dr. Fowler A.P.Dr. Wolf (Title/Position) Co-Director Co-Director Other senior staff: [3] Type of cyclotron: Positive Ion Manufacturer: JSW Model: 1710 Year: (i) of installation: 1982 majoy an (lif ro )reconstruction : [4] Particle beams available: B ^*H *H x -A {. P SO. 'He 'He Dual Beams * * < I Beam energies/Range 17 10 (MeV) Typical currentt in s 60 50 GiA) Employet ex d 40 30 (MA) Hour weer spe k machin operation i s ei n (excluding maintenance): 6000fiA-h targeton 1994in Hour r weespe k employe radionuclidn di e production: Hours per week machine maintenance: Additional applications of the cyclotron: PETIsotope proudction95% Basic research 5% Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: Basic research in house 100% Applied programme in house 100% 397 ] [5 Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) batcr pe h ] [6 Radionuclides planne producee b o dneae t th rn d i future : [7] Major radiopharmaceuticals produced: [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? If yes, which ones and how often? [9] Is medical research/diagnosis carried out on site/off site? siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? 398 UNITED STATES OF AMERICA USA-50 [I] Institute: Carolinas Medical Center Postal Address: 32861Box O. P. CharlottenNC 28232 Telephone: 3555910704 1 Fax/E-mail: 35536291-704 ] [2 Person m-charge: Dr. Edward Easton (Title/Position) Medical Director Other senior staff: Ronald D. Borchert, David M. Coates, Michael Johnson, Andy McKusick, Kevin Larcher ] [3 Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 (n) of any major reconstruction [4] Particle beams available: J *H J ?''.^ - He "He Dual Beams Beam energies/Range 11 (MeV) Typical currents int. 10-40 (fiA) Employed external 20-40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 10 Hour weer spe k employe radionuclidn di e production: 10 Hour weer spe k machine maintenance: 3 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 399 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) frequency Comments Produced (enrichment) batcr pe h "N H2'°0 2 2 per week S «F H2' O (97-98%) 30 5 per week [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: !8F-FDG, '*F-Fluoride 13N-Ammonia supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Planned yesf I , whic oftenw h ho one ?d san medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Diagnosis On site If on site, indicate imaging devices available number *511KeVSPET / * Gamma camera * Single Photon Tomography (SPET) Positro* n Emission Tomograph7 y (PET) engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo ? No 400 UNITED STATES OF AMERICA USA-51 [1] Institute: Duke University Medical Centre Postal Address: Department of Radiology 3808,Box Durham, NC 27710 Telephone: 1-919-6847708 Fax/E-mail: 1-919-6847121; [email protected] [2] Person in-charge: Dr. Bruce Wieland Dr. Michael Zalutsky (Title/Position) Director, Cyclotron Professor Other senior staff: ] [3 Typ cyclotronf eo : Isochronous Fixed Field, PositiveIon Manufacturer: The Cyclotron Corporation Model: CS-30 Year: (i) of installation: 1985 majory an (iif o )reconstruction : ] [4 Particle beams available: *te *H "He *«« Baal Beams Beam energies/Range 27.6 14 28.3 (MeV) Typical currents int 120 120 100 (UA) Employet ex d 70 70 50 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 32 Hours per week employed in radionuclide production: 32 Hour weer spe k machine maintenance: 8 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 401 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "V '"Te02 0.1 week4per '"At na'Bi 1 1 per week internal target ] [6 Radionuclides planne producee b o dneat e th rn d i future : ] [7 Major radiopharmaceuticals produced: 18T-FDG 211At-labelled antibodies [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosi siten O s carrie site/ofn o t dou f site? If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections No Thics kYe target yields o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 402 UNITED STATE AMERICF SO A USA-52 [I] Institute: Bowman Gray School of Medicine Postal Address: Medical Centre Blvd Winston-Salem, NC 27157 Telephone: 1- 910-7167461 Fax/E-mail: [2] Person in-charge: Dr. Richard L. Witcofski (Title/Position) Director Other senior staff: Richard Ehrenkaufer Henry Chilian [3] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 majoy an (ii f r)o reconstruction [4] Particle beams available: *'. .. ,,.?H "He *He Dual Beams Beam energies/Range ;; yes (MeV) Typical currents int. (uA) Employed external 40 (HA) Hours per week machine is in operation (excluding maintenance): 15 Hour weer spe k employe radionuchdn di e production: 15 Hours per week machine maintenance: 1 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 403 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch 14N 37 n"C week1per o I3N 7 6 per week a lts «F H2' O (96%) 40 7 per week H2 O Recovered ] [6 Radionuclides planne producee b o dneat e th rn di future : [7] Major radiopharmaceuticals produced: F-FDG C- Methionine 'O-Water supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? Yes If yes, which ones and how often? 18F-FDG Daily We will supply otherto institutions beginning June,in 1997. medicas I ] l[9 research/diagnosis carrie site/ofn o t dou f site? Research& diagnosis on site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 404 UNITED STATE AMERICF SO A USA-53 [I] Institute: The Christ Hospital Postal Address: 2139 Auburn Avenue Cincinnati, 45219OH Telephone- 1-513-3698833 Fax/E-mail: [email protected] com [2] Person m-charge: Thomas G. Kemme (Title/Position) Manager Other senior staff Carla PembertonC. [3] Typ cyclotronf eo : NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 (n) of any major reconstruction [4] Particle beams available: IHr i , *He 'He Dual Beams :?T'* Beam energies/Range 11 yes (MeV) Typical currents int. Employed external 5-40 40- <50 OiA) Hours per week machine is in operation (excluding maintenance): 40 Hours per week employed in radionuchde production: Hours per week machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 405 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced ^enrichment) per batch l "C *N3 +2.5%O2 6 / -2 per month EOS ( "N H2 O5mMEtOti+ 1 ~ 2 per week S >«F H2' 0 25 4 per -week ] [6 Radionuclides planne producee b neao de t th r n di future : [7] Major radiopharmaceuticals produced: 18T-FDG 13N-Ammonia 11C-Acetate [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No Not presentat If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? Diagnosis siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera 6 * Single Photon Tomography (SPET) 3 * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a [10reactio] n cross-section measurements? No . b Which typ nucleaf eo useu r datyo ? o ad Reaction croso sN sections Thico kN target yields o N Decay data [11] Does your institute accept IAEA research fellows for training/experience? No 406 UNITED STATES OF AMERICA USA-54 [1] Institute: Case Western Reserve University Postal Address: and University Hospitals of Cleveland Division of Radiology 11100 Euclid Avenue Cleveland, OH 44139 Telephone: 1-216-8447350 Fax/E-mail: msb5@po. cwru.edu [2] Person in-charge: Marc Berridge (Title/Position) Associate Professor Other senior staff: Zheng; Lei VoelkerKen [3] Typ cyclotronf eo : Scanditronix Manufacturer: Model: MC-17 Year: (i) of installation: 7955 majoy an f (iir o reconstruction) : [4] Particle beams available: •J*T .s. »&. \ jJnrr * f • . >^He.,, . . "He Dual Beams . . "«• i? ; ; "fk " ' ,^ ^ * j ? TV ( Beam energies/Range 17 8 (MeV) Typical currentt in s (uA) Employet dex 30 40 (HA) Hour weer spe k machin operation i s ei n (excluding maintenance): 25 Hours per week employed in radionuclide production: 25 Hours per week machine maintenance: av. 6 (some weeks, none) Additional application cyclotrone th f so : radionuclidePET production exclusively Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 407 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch a "C " 'N2 75 week10per various synthetic products IJN na'//,0 31 variable 5-35per week n na o 'N2 25 15 per week <* S a F H2' 0 33 week6per H2' O recovery [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: supplu yo o yD radionuclides/radiopharmaceutical ] [8 otheo st r institutions? Yes If yes, which ones and how often? Radionuclides/radiochemicals (not radiopharmaceuticals) 18F- Fluoride 13'N-Ammonia 18, - FDG medicas I ] l[9 research/diagnosis carriesite/ofn o t dou f site? Yes If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera 2 * Single Photon Tomography (SPET) 3 Positro* n Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? 408 UNITED STATES OF AMERICA USA-55 [I] Institute: Kettering Medical Centre Postal Address: Department of Nuclear Medicine and PET 3535 Southern Blvd Kettering, OH 45429 Telephone: 1-937-296 7211 Fax/E-mail: 1-937-296 4265 [2] Person m-charge: Dr. Joseph Mantil (Title/Position) Other senior staff: [3] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1989 majoy an (iif ro )reconstructio n [4] Particle beams available: l m j -~, SB Baal Beams £ Hours per week machine is in operation (excluding maintenance): 12 Hour weer spe k employe radionuclidn di e production: 12 Hours per week machine maintenance: 1 Additional application cyclotrone th f so : Radiotherapy/Activation Analy sis/Radiobiology/Phy sics: Others: 409 ] [5 Radionuclides produced: Radionndide Target Material Activtty(GBq) Frequency Comments Produced (enrichment) pertoatch "C "N, 22 2 per week "N H2O 1.8 2 per week /3»r "0 N2 3.7 0.385 weekper ISp 1S H2 O (96%) 11-22 5 per week [6] Radionuclides planne producee b o dneat e th r n dfuturei : [7] Major radiopharmaceuticals produced: I8F-FDG C-Methionine '5O-Water 13N-Ammonia [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) / [10] a. Are you engaged in nuclear reaction cross-section measurements? No . b Which typ nucleaf eo useu r dat?yo o ad Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/expenencer sfo o N ? 410 UNITED STATE AMERICF SO A USA-56 [1] Institute: University of Pennsylvania Postal Address: Department of Radiology 1 Silverstein Philadelphia, 19104PA Telephone: 1-215-6627552 Fax/E-mail: 1-215-6627551; [email protected] [2] Person in-charge: CarlosDr. Gonzalez Lepera (Title/Position) Facility Manager Other senior staff: Harry White [3] Typ cyclotronf eo : PositiveIon Manufacturer: Japan Steel Works Model: BC3015 installationf Yearo ) (i : : 1986 majoy an f (iiro )reconstructio n ] [4 Particle beams available: i-Br ?, Hours per week machine is in operation (excluding maintenance): 75 Hour weer spe k employe radionuclidn di e production: 12 Hours per week machine maintenance: 8 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 411 [5] Radionuclides produced: Radionndide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C Ni (100% VHP) 25 weekper 3 IJ N H2O (natural) 4 weekper 2 + EtOH n n o "N2 (95%) 1.5minuteper 3 per week H2 O + 5%H, continousflow " e S F H2' O (97%) 40 week4per H2' O not recovered "Na '""Mg 0.04 year1per calibration source [6] Radionuclides planne producee b neao de t th rn di future : 55Co 89'Zr [7] Major radiopharmaceuticals produced: F-FDG N-Ammonia C-Flumazenil O- Water [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) 7 * Positron Emission Tomography (PET) 2 engageu yo e nuclean dAr i . r[10 a reactio] n cross-section measurements? Yes b. Which typ nucleaf eo useu r datyo ? o ad Reaction cross sections Yes Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? Yes 412 UNITED STATE AMERICF SO A USA-57 [1] Institute: University ofPittsburg FacilityPET Postal Address: Presbyterian University Hospital, B-932 Lotlrop200 Street Pittsburg, 15213PA Telephone: 1-412-6470736 Fax/E-mail: 1-412-6470700; [email protected] [2] Person in-charge: Prof. Chet Mathis Prof. David Townsend (Title/Position) Co-Director FacilityPET Co-Director FacilityPET Other senior staff: [3 ] Type of cyclotron: NegativeIon Manufacturer: CTI Model: RDS112 installationf Yearo ) (i : : 1991 majoy an (iif r o )reconstructio n ] [4 Particle beams available: i_, , ^,.5,, , ~*ji . - ' « ,¥ , *He Dual Beams " ^ipLi i Hour weer spe k machin operation i s ei n (excluding maintenance): -40 Hour weer spe k employe radionuclidn di e production: -40 Hours per week machine maintenance: ~5 Additional application cyclotrone th f so : Production of PET radionuclides Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 413 [5] Radionuclides produced: Radionnclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch > "C " N+1%O2 -37 -30 per week "N H '°O +EtOH n 2 -10 weekper -10 o "N+1%O2 -20 -80 per week "F H2'*O(96%) -25 -10 per week [6] Radionuclides planned to be produced in the near future: additionalNo [7] Major radiopharmaceuticals produced: 18F-FDG, ™F-Altanserin 5 I5 H2' 0, 0-02, N-Ammonia "C-Methionine, nC-SCH23390, "C-Raclopride, "C-WAY100635, "C-Flumazenil, "C-MCN5652X, "C-MDL100907, "C-SR46349B supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? medicas I ] l[9 research/diagnosi siten O s carriesite/ofn o t dou f site? siten o ,f I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 3 engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurementso N ? b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 414 UNITED STATES OF AMERICA USA-58 ] [1 Institute: University ofTennesse Medical Centre Postal Address: Department of Radiology /PET 1924 Alcoa Highway Knoxville 37920TN Telephone: 1-423- 5449700 Fax/E-mail: 1-423-5448883; Longford@scanner. hasp. utk.edu [2] Person in-charge: Dr. G. T. Smith (Title/Position) Director, ClinicalPET Other senior staff: Hubner;F. Kabalka; W. K. G. LangfordD. C.P. ] [3 Typ cyclotronf eo : Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1987 majoy an (iif r o )reconstructio n [4] Particle beams available: J - %ffs--**r ,; r>< w-||$3< £384jKriii;«ls™5 " ' ""1"s!"^ll , Beam energies/Range /; (MeV) Typical currents int. (uA) Employed external 20-40 (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): -15 Hours per week employed in radionuclide production: -15 Hour weer spe k machine maintenance: -3 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 415 ] [5 Radionuclides produced: Radionaclide Target Material Activity (GBq) Frequency Comments Produced (enrichment) per batch "C "N2 ; '°O2 (99:1) 45 2 per month UN HyO IvMEtOH+ 1-2 weekper 20 - 0 "0 '*N, (>95%) 45 1-2 per year >«F 98%)(. HfO 25 weekper 6 5- '« lf F O2 (> 98%) 20 monthper 2 ] [6 Radionuclides planne producee b o neadt e th rn d i future : ] [7 Major radiopharmaceuticals produced: 13N- Ammonia 18, 90% of our work ISF-DOPA, I8F-Borono-2-fluoro-L-phenylalanine 11 C- 1-Aminocyclobutane carboxylic acid, "C- Acetate, C- D,L-Tryptophan, C- Methionine [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san We intend to become a distribution centre forF-FDG I8 nextmonthsinthe 2-3 [9] Is medical research/diagnosis carried out on site/off site? On site If on site, indicate imaging devices available number *511KeVSPET Gamm* a camera 7 * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 2 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Thick target yields Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? Yes 416 UNITED STATE AMERICF SO A USA-59 [1] Institute: Vanderbilt University Postal Address: Radiology Department Nashville, TN37232-6315 Telephone: 1-615-3437511 Fax/E-mail: 1-615-3436531 [2] Person in-charge: RonaldDr. ManningG. (Title/Position) Other senior staff: JeffClauton; Dominique Delbeke; Robert Kessler [3] Type of cyclotron: Negative Ion Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1989 (ii) of any major reconstruction [4] Particle beams available: 1 ,1 Iff H • :* • ^ ,- «B* Dual Beams ",~ life::%; -• - Beam energies/Range 11 (MeV) Typical currents int. 80 (HA) Employed external (uA) Hour weer spe k machin operation i s ei n (excluding maintenance): 25 Hour weer spe k employe radionuclidn di e production: 25 Hour weer spe k machine maintenance: 20 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 417 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced (enrichment} peftatch "C "N, 40 week5per n"N H2'"0 36 1 per week o '*N2 50 weekper I /Sp. a H2' O 55 week15per [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: F-FDG 'N- Ammonia supplu yo o y D [8radionuclides/radiopharmaceutical] otheo st r institutions? Yes If yes, which ones and how often? PETNet Site Several 15 Customers > [9] Is medical research/diagnosis carried out on site/off site? Both If on site, indicate imaging devices available number *511KeVSPET 1 * Gamma camera * Single Photon Tomography (SPET) 4 * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections No Thick target yields No o N Decay data [11] Does your institute accept IAEA research fellows for training/expenence? No 418 UNITED STATE AMERICF SO A USA-60 [1] Institute- Oak Ridge National Laboratory Postal Address: BLDG 6000, 6368MS Oak Ridge TN 37831-6368 Telephone: 1-423-5744111 Fax/E-mail: 1-423-5741268 [2] Person m-charge: B.A. Tatum (Title/Position) Engineering Manager Other senior staff. S. W. Mosko [3] Type of cyclotron: K=100 Isochronous Manufacturer: ORNL Model: installationf Yearo ) (i : : 1960 (n) of any major reconstruction: ] [4 Particle beams available. f t H »ji U.^H , *m* * "^He Dual Beams T&-~' Beam energies/Range <60 <40 (MeV) Typical currents mt < 100 <200 (UA) Employet ex d <50 <100 (uA) Hours per week machine is in operation (excluding maintenance)- 20 Hours per week employed in radionuclide production Hours per week machine maintenance: 40 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others 419 [5] Radionuchdes produced: Radionnclide Target Material Activity j ; frequency Comments Produced (enrichment) (GBq) per " : batch [6] Radionuchdes planned to be produced in the near future: [7] Major radiopharmaceuticals produced: supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions7 No If yes, which ones and how often? [9] Is medical research/diagnosis earned out on site/off site? No siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera Singl* e Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i r. a [10reactio] n cross-section measurementss Ye ? b. Which type of nuclear data do you use9 Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for trammg/expenence? No 420 UNITED STATES OF AMERICA USA-61 ] [1 Institute: Texas A&M Cyclotron Institute Postal Address: Texas A&M University College Station, 77843-3366TX Telephone: 1-409-8451411 Fax/E-mail: 1-409-8451899; [email protected] ] [2 Person in-charge: J.B. Natowitz (Title/Position) Director Other senior staff: D. May; F. Abegglen [3 ] Typ cyclotronf eo : Superconducting SourcewithECR Manufacturer: TAMU Model: K500 Year: (i) of installation: 1989 majoy an f ro (iireconstruction) : [4] Particle beams available: taJBL,- <..*{,•:><•=. « % *He "He Dual Beams ; „ -,J, *§• 1:.'.'^ t ' £.-*,-i Beam energies/Range 60 120 130 240 (MeV) Typical currents mt (uA) Employet ex d 0.2 0.1 0.2 0.1 (uA) Hours per week machine is in operation (excluding maintenance): 160 Hour weer spe k employe radionuclidn di e production: Hour weer spe k machine maintenance: Additional applications of the cyclotron: Radiotherapy/Activation Analy sis/Radiobiology/Phy sics: Others: Protons, deuterons, alphas, 6Li, '°B, I2C, I4N, I620O,Neand can be run at 67 MeV/nucleon. For ions equal to or larger than lowermassthe 10, energy limit MeV/nucleon.2 is 421 ] [5 Radionuclides produced: Radionuclide ^Freqnency Comments Produced : perbatch ; (enrichment) ] [6 Radionuclides planne producee b o dneat e th rn d i future : [7] Major radiopharmaceuticals produced: [8] Do you supply radionuchdes/radiopharmaceuticals to other institutions? No If yes, whic oftenw h ho one ?d san [9] Is medical research/diagnosis earned out on site/off site? No If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes . b Which typ nucleaf eo useu r datyo ? o ad Reaction cross sYe sections Thick target yields No Decay data Yes [11] Does your institute accept IAEA research fellow training/experiencer sfo s Ye ? 422 UNITED STATES OF AMERICA USA-62 [I] Institute: University Texasof Health Centre Houstonat Postal Address: 6431 Fannin Street, Houston, 77030TX Telephone: 7-773-5007755 Fax/E-mail: 3-5077 -7 0 7777; [email protected]. uth. tmc.u ed [2] Person in-charge: Leonard A. Bolomey (Title/Position) Executive Director Other senior staff: Frank R. Dobbs [3] Type of cyclotron: Variable Energy Isochronous Manufacturer: Scanditronix Model: MC-40 Year: (i) of installation: 7953 (ii) of any major reconstruction: [4] Particle beams available: In- « -s "He Dnal Beams , M . -. 'jj^,;-;^H "He Beam energies/Range 8-40 4-20 5-50 8-40 (MeV) Typical currents int 400 400 700 100 (uA) Employed ext 75 75 50 50 (uA) Hours per week machine is in operation (excluding maintenance): 35 Hour weer spe k employe radionuclidn di e production: 35 Hours per week machine maintenance: <4 Additional applications of the cyclotron: Radiotherapy/ Activation Analysis/Radiobiology/Physics: Others: 423 [5] Radionuclides produced: Radionnclide I. Target Activity (GBq) Frequency Comments Produced *:: batcr pe h (enrichment) "N H2O 1.8 10 per week "0 3.7 week1per w N2 z« natCu 12 week1per "'Ga oaZn 370 1 per week enriched MZn reocovery '"In luCd 370 1 per week enriched '"Cd recovery 1/y w na'Ta 18.5 week1per [6] Radionuclides planne producee b o dneae t th rn di future : 57Co,K 38 [7] Maj or radiopharmaceuticals produced: nF-FDG [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes If yes, which ones and how often? Columbia Hospital Medicalat Cityweekper Dallas4 Dallas, TX Presbyterian Hospital of Dallas Dallas, TX 1 per week University Texasof Medical Branch month per 1 Galveston, TX Hermann Hospital Houston, TX 12 per week Mount Sinai Medical Centre Miamiweekper 1 Beach, FL [9] Is medical research/diagnosis carried out on site/off site? On site siten Ifo , indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sYe sections Thics kYe target yields s Ye Decay data [11] Does your institute accept IAEA research fellows for training/expenence? 424 UNITED STATES OF AMERICA USA-63 [1] Institute: University of Texas Research Imaging Centre Postal Address: Health Science Centre, San Antonia 7703 Floyd Curl Drive Antonio,San 78284TX Telephone: 1-210-567-8190 Fax/E-mail: 1-2 JO-5678152; [email protected] [2] Person in-charge: Dr. Peter Fox (Title/Position) Director Other senior staff: Paul Jerabbk [3] Type of cyclotron: Fixed Energy, Isochronous, Positive Ion Manufacturer: Scanditronix Model: MC17F installationf Yearo ) (i : : 1991 (ii) of any major reconstruction: ] [4 Particle beams available: «f, l" s 1:* ;;;.' "Be ! ' " "He Dual Beams * OJt " t*£t$4 v»- i v 3, Beam energies/Range 17.2 8.6 (MeV) Typical currentt in s <10 <10 (UA) Employed ext 10-50 10-40 (HA) Hours per week machine is in operation (excluding maintenance): 3-5 Hour weer spe k employe radionuclidn di 5 3- e production: Hours per week machine maintenance: 1 Additional applications of the cyclotron: Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 425 [5] Radionuclides produced: Radionuclide Target Material Activity (GBq) Frequency Comments Produced "" (enrichiiteBi:) rd%wrttarteii .,', "C N2+ 0.5% O2 7.4 - 92-5 ~ 20 per year n"N H2O 3.7-7.4 ~ 20 per year o N2+l%2 O 14.8-18.5 40-50 '« F Ne+l%F2 13 "F-F2 <* lls F H2 O (>95%) 18.5 - 22 1-3-weekper [6] Radionuclides planne producee b o dneat e th r n dfuturei : [7] Major radiopharmaceuticals produced: F-FDG O-Water N-Ammonia "C-Acetate. "C-Methionine supplu yo o y D radionuclides/radiopharmaceutical[8] otheo st r institutions? No If yes, which ones and how often? We do not currently supply radionuclides / radiopharmaceuticals to other institutions. However, planningare we to distribute !8F-FDG in thefutute (1998). medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 7 engageu yo e nuclean dAr i [10r. a reactio] n cross-section measurements? No b. Which type of nuclear data do you use? Reaction croso sN sections Thick target yields No Decay data No [11] Does your institute accept IAEA research fellows for training/experience? Yes 426 UNITED STATE AMERICF SO A USA-64 [1] Institute: University of Washington Medical Centre Postal Address: Department of Radiation Oncology Box 356043, Room NN-136 1959PacificNE Street Seattle, WA 98195-6043 Telephone: 1-206-5484136 Fax/E-mail: 1 -206-5486218; risler@radonc. Washington, edu [2] Person in-charge: Dr. Ruedi Risler (Title/Position) Senior Cyclotron Engineer Other senior staff: Kenneth KrohnA. Jeanne A. Link [3] Type of cyclotron: Compact Room Temperature Cyclotron Manufacturer: Scanditronix Model: MC-50 installationf Yearo ) (i : : 1983/84 (ii) of any major reconstruction: ] [4 Particle beams available: f^s^&Ute^r-- 4s , s2^***^ ^"g V ^--f iBfe ^ lEfo Dnal Beams : ' 5" %isj-- '- afFtl|jff?!'>>3*"K*3r Beam energies/Range 25-57 75-25 27-35 30-48 (MeV) Typical currentt in s (HA) Employet ex d 70 50 2 0.75 (HA) Hours per week machine is in operation (excluding maintenance): 40 Hour weer spe k employe radionuclidn di e production: 1.5 Hour weer spe k machine maintenance: 8 Additional applications of the cyclotron: Primary use is for neutron therapy Radiotherapy/Activation Analysis/Radiobiology/Physics: Others.- Production radionuclides ofPET 427 [5] Radionuclides produced: Radionnclide Target Material Activity(GBq) Frequency Comments Produced fenrichmeiity per batch n"C N2 30 - 100 10 per week o 02 12 weekper 2 "f 1S S H2 O (>95%) 15 6 per week H2' O recovery iyNe "Ne 10 week2per flow through target [6] Radionuclides planned to be produced in the near future: 87V [7] Major radiopharmaceuticals produced: F-FDG, F-Fluoromisonidazole, F-Fluoroetanidazole, I8F-Fluoroestradiol, I8F-FLT * * C-1-D-Glucose, 11,C-Thymididne, C-meta-Hydorxyephedrine, C-CGP12177, "C-Carbon Dioxide, "C-Methane 15O-Water, 15O-Oxygen [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? No If yes, which ones and how often? medicas I [9] l research/diagnosis carriesite/ofn o t dou f site? On site siten Ifo , indicate imaging devices available number *511KeVSPET Gamm* a camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) engageu yo e nuclean dAr i [10. ra reactio] n cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sections Yes Thics kYe target yields Decay data Yes [11] Does your institute accept IAEA research fellows for training/experience? Yes 428 UNITED STATES OF AMERICA USA-65 [1] Institute: West Virginia University CentrePET Postal Address: 9236,P.O.Box Morgantown WV26506-9236 Telephone: 1-304-2937798 Fax/E-mail: 1-304-293 7142; smazza@wvuhsd. hsc. wvu.edu ] [2 Person m-charge: Dr. Naresh C. Gupta (Title/Position) Director Other senior staff: Samuel M. Mazza Raymond R. Raylman [3] Typ cyclotronf eo : Negative Ion, Dual Beam Manufacturer: General Electric Model: PETTrace installationf Yearo ) (i : : 1995 majoy an (ii f r) o reconstruction : [4] Particle beams available: • '-•" If* "He "He Dual Beams ** s?H$g ^ i •W-^V~ , M,O *~ Beam energies/Range 16.5 8.5 yes (MeV) Typical currentt in s (uA) Employed ext 20 10 (uA) Hours per week machine is m operation (excluding maintenance): 5 Hours per week employed in radionuclide production: 5 Hours per week machine maintenance: 7 Additional application cyclotrone th f so : Radiotherapy/Activation Analysis/Radiobiology/Physics: Others: 429 [5] Radionuclides produced: Radionuclide Target Material Activity Frequency Comments Produced (enrichment) (GBq)per batch n"N H2O 3 per week o N2 Irregularly •« 1S F H2 O (97%) week5per [6] Radionuclides planned to be produced in the near future: ] [7 Major radiopharmaceuticals produced: F-FDG N-Ammonia O-Water suppl[8u ]yo o y D radionuclides/radiopharmaceutical otheo st r institutions? Yes If yes, which ones and how often? FFluoride, Irregularly 10F-FDG Planned [9] medicas I l research/diagnosis earnesite/ofn o t dou f site? On site siten o f , I indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) 1 [10] a. Are you engaged in nuclear reaction cross-section measurements? No b. Which type of nuclear data do you use? Reaction cross sections Yes Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellows for training/experience? 430 UNITED STATES OF AMERICA USA-66 [1] Institute: University Wisconsinof Postal Address: Medical Physics Department 1530MSC 1300 University Avenue Madison, WI53706 Telephone: 1-6082631024 Fax/E-mail: 1-608 2633910 [2] Person in-charge: NickelsProf.J. R. (Title/Position) Other senior staff: Andrew Roberts, Onofre deJesus [3] Typ cyclotronf eo : Negative Ion, Isochronous Manufacturer: CTI Model: RDS112 Year: (i) of installation: 1986 majoy an (iif r o )reconstructio n [4] Particle beams available: •'-,: ^H® , Dual Beams '• :,^i% Beam energies/Range 11 yes (MeV) Typical currents int. (uA) Employed external 50 Hours per week machine is in operation (excluding maintenance): ~8 Hours per week employed in radionuclide production: ~ 8 Hour weer spe k machine maintenance: ~ 1 Additional application cyclotrone th f so : Irradiating cardiac stents, Teaching, Target Development Radiotherapy/Activation Analysis/Radiobiology/Physics: Fast neutron activation analysis Others: 431 [5] Radionuclides produced: Radionnclide I'arget Material Activity(GBq) Frdjufincy Comments Produced (enrichment) ; per batch "C 1VB (99.9%) 4 Occassionally Steady-state 14\r "C N2 ~ 4 Occasionally "N H 2SvMEtOHO+ ~4 0 - 20 per week "0 Ni 100 Occasionally "Mn, JOCo 316 Stainless Steel kBq 400 Occassionally Radioactive stents wCu natNi MBq 200 Occassionally natMo 200 MBq Occassionally ISp 9 e H2' O (96%) 20-60 3 per week H2' O Recovered [6] Radionuclides planned to be produced in the near future: [7] Major radiopharmaceuticals produced: N- Ammonia I8F-FDG, I8F-DOPA, I8F-FTHA, ISF-meta-Tyrosine, 18F-Fluoromethane, 18F-MISO, ~dozena F-labelledto anesthetics 94mTc-BATO, 94mTc-MIBI, 94mTc-BSM-194,796 [8] Do you supply radionuclides/radiopharmaceuticals to other institutions? yesf I , whic oftenw h ho one ?d san [9] Is medical research/diagnosis carried out on site/off site? Both If on site, indicate imaging devices available number *511KeVSPET * Gamma camera * Single Photon Tomography (SPET) * Positron Emission Tomography (PET) [10] a. Are you engaged in nuclear reaction cross-section measurements? Yes b. Which type of nuclear data do you use? Reaction cross sYe sections Thick target yields Yes s Ye Decay data [11] Does your institute accept IAEA research fellow training/experiencer sfo ? 432 SAMPL QUESTIONNAIRF EO E QUESTIONNAIRE ON CYCLOTRON RADIONUCLIDE PRODUCTION Pleas( equestionnaire filon l cyclotror epe returd nan y n______b ) _ (1) INSTITUTE: ...... COUNTRY PostalAddress:...... -...... Fax/E-mail...... ...... Telephone ...... (2) PERSON IN-CHARGE (Title/Position). OTHER SENIOR STAFF...... (3) Type of Cyclotron ...... Manufacturer ...... Model installatiof o Yea ) (i r n ...... (ii) of any major reconstruction ...... (4) PARTICLE BEAMS AVAILABLE 'H 2H 3He 4He Dual beams Beam energies/Range (MeV) Typical currents int employed ext Hour weer spe k machin operation i es i n (excluding maintenance) Hoursperweekemployed inradionuclideproduction ...... Hours per week machine maintenance ...... 433 Additional application cyclotrone th f so : Radiotherapy/Activation analysis/Radiobiology/Physics Others ...... (5) Radionuclides produced Radionuclide Target Activity Frequency Comments Produced Material (GBq) (enrichment) per batch « IS F H2 O (96%) SO GBq 4 per week Enriched water recovery (6) Radionuclides planne producee b neao e dt th rn di future . (7) Major radiopharmaceuticals produced. 434 (8) Do you supply radionuclides/radiopharmaceuticals to other institutions? Yes/No. If yes, which ones and how often ? medicas (9I ) l research/diagnosis carriesite/ofn o t dou f site If on site, indicate imaging devices available number (* Delete where not applicable) * 511 KeV SPET...... * Single photon tomography (SPET). * Gamma camera...... *Positrontomography(PET)...... engageu yo e nuclean di Ar (10 . ra )reactio n cross-section measurements? (Yes/No) b. Which typ f nucleaeo useu r datyo ? o ad Reaction cross sections (Yes/No) Thick taret yields (Yes/No) Decay data (Yes/No) (11) Other comments: 435 (12) Does your Institute accept IAEA research fellow training/experiencer sfo ? Yes/No (13) Name of person completing questionnaire. Date. PLEASE RETURN THIS FOR: MTO Dr. Hernan Vera Ruiz Head, Industrial Applications and Chemistry Section International Atomic Energy Agency 0 10 P.Ox Bo . A-1400 Vienna, AUSTRIA 2061 [Telephon 3 0 21748+4 . ]eNo [Fax No. +43 1 20607] [E Mail: [email protected]] 436