URL: www.sceti.jp/export/ E-mail: [email protected] KB512 For research use only Anti Human CACNB1 Polyclonal Antibody 0

Code No. KB512 Terget CACNB1 Category Transporter Gene ID 782 Primary Source HGNC:1401 Synonyms CAB1; CCHLB1; CACNLB1; MGC41896; CACNB1

[WB] CACNB1 transfected 293T cell lysate Type Polyclonal Antibody Immunogen Recombinant protein of full length Human CACNB1

Raised in Mouse Myeloma - Clone number - Purification Protein A purified 0 Source Mouse Serum Isotype - Cross Reactivity - Label Unlabeled Concentration 0.5 mg/mL Contents（Volume） 50 μg Buffer PBS, pH 7.2 0

Storage Store at - 20 ℃ long term, store at 4 ℃ short term. Avoid repeated freeze-thaw cycles. Application WB ELISA WB IHC ICC - 1.0 - - IP FCM IF Neutralization ---- (μg/mL) 0 Reference 1. Powers P.A., et al. "Skeletal muscle and brain isoforms of a beta-subunit of human voltage-dependent calcium channels are encoded by a single gene." J. Biol. Chem. 267:22967-22972(1992) 2. Collin T., et al. "Molecular cloning of three isoforms of the L-type voltage-dependent calcium channel beta subunit from normal human heart." Circ. Res. 72:1337-1344(1993) 3. Fukuda K., et al. "Cyclic AMP-dependent modulation of N- and Q-type Ca2+ channels expressed in Xenopus oocytes." Neurosci. Lett. 217:13-16(1996) UniPlot Summary //Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. //Subcellular location: Cell membrane › sarcolemma; Peripheral membrane protein; Cytoplasmic side. //Tissue specificity: Expressed in brain, heart and spleen (isoform 1 and 3) and in skeletal muscle (isoform 2). //Sequence similarities Belongs to the calcium channel beta subunit family. Contains 1 SH3 domain.

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